ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A01 compound treatment 94770.0 -286000.0 -1.93 116090.0 -276000.0 -2.0 -2.7772 -0.9999 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A02 compound treatment 81040.0 -299000.0 -2.02 95690.0 -296000.0 -2.14 -2.9473 -0.9996 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A03 compound treatment 223780.0 -157000.0 -1.06 252330.0 -140000.0 -1.01 -1.4635 -0.9997 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A04 compound treatment 281960.0 -98500.0 -0.67 296640.0 -95300.0 -0.69 -0.9587 -0.9998 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A05 compound treatment 170110.0 -210000.0 -1.42 260640.0 -131000.0 -0.95 -1.6774 -0.9809 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A06 compound treatment 165760.0 -215000.0 -1.45 212320.0 -180000.0 -1.3 -1.9455 -0.9985 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A07 compound treatment 149060.0 -231000.0 -1.56 240210.0 -152000.0 -1.1 -1.8825 -0.9851 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A08 compound treatment 251780.0 -129000.0 -0.87 273190.0 -119000.0 -0.86 -1.2229 -1.0 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A09 compound treatment 303460.0 -77000.0 -0.52 248220.0 -144000.0 -1.04 -1.1038 -0.9487 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A10 compound treatment 168160.0 -212000.0 -1.43 184160.0 -208000.0 -1.5 -2.0782 -0.9997 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A11 compound treatment 267940.0 -113000.0 -0.76 217470.0 -175000.0 -1.26 -1.4309 -0.9705 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A12 compound treatment 230310.0 -150000.0 -1.01 230560.0 -161000.0 -1.17 -1.5437 -0.9975 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A13 mock treatment 403630.0 23200.0 0.16 279130.0 -113000.0 -0.82 -0.467 -0.5615 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A14 mock treatment 312660.0 -67800.0 -0.46 347870.0 -44100.0 -0.32 -0.5498 -0.9844 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A15 compound treatment 123840.0 -257000.0 -1.73 136840.0 -255000.0 -1.85 -2.5321 -0.9995 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A16 compound treatment 191930.0 -189000.0 -1.27 202420.0 -190000.0 -1.37 -1.8711 -0.9993 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A17 compound treatment 341800.0 -38700.0 -0.26 353880.0 -38100.0 -0.28 -0.3798 -0.9996 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A18 compound treatment 141330.0 -239000.0 -1.62 157770.0 -234000.0 -1.7 -2.3414 -0.9997 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A19 compound treatment 104220.0 -276000.0 -1.87 109130.0 -283000.0 -2.05 -2.7677 -0.9989 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A20 compound treatment 191970.0 -189000.0 -1.27 204110.0 -188000.0 -1.36 -1.8623 -0.9995 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A21 compound treatment 249600.0 -131000.0 -0.88 255040.0 -137000.0 -0.99 -1.3262 -0.9984 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A22 compound treatment 215010.0 -165000.0 -1.12 243640.0 -148000.0 -1.07 -1.5499 -0.9998 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A23 compound treatment 350040.0 -30400.0 -0.21 252380.0 -140000.0 -1.01 -0.86 -0.8339 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 A24 compound treatment 165210.0 -215000.0 -1.45 187360.0 -205000.0 -1.48 -2.0759 -1.0 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B01 compound treatment 223040.0 -157000.0 -1.06 273140.0 -119000.0 -0.86 -1.3605 -0.9945 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B02 compound treatment 363700.0 -16800.0 -0.11 280230.0 -112000.0 -0.81 -0.6522 -0.7984 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B03 compound treatment 217830.0 -163000.0 -1.1 209530.0 -182000.0 -1.32 -1.711 -0.9958 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B04 compound treatment 286190.0 -94300.0 -0.64 318690.0 -73300.0 -0.53 -0.8256 -0.9959 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B05 compound treatment 187940.0 -193000.0 -1.3 200400.0 -192000.0 -1.39 -1.9005 -0.9995 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B06 compound treatment 344270.0 -36200.0 -0.24 422150.0 30200.0 0.22 -0.0185 -0.0566 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B07 compound treatment 232870.0 -148000.0 -1.0 431270.0 39300.0 0.28 -0.5041 -0.4861 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B08 compound treatment 77400.0 -303000.0 -2.05 127680.0 -264000.0 -1.91 -2.8009 -0.9994 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B09 compound treatment 180120.0 -200000.0 -1.35 229440.0 -163000.0 -1.18 -1.7892 -0.9976 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B10 compound treatment 132580.0 -248000.0 -1.67 249090.0 -143000.0 -1.03 -1.9158 -0.9732 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B11 compound treatment 169670.0 -211000.0 -1.42 159800.0 -232000.0 -1.68 -2.1956 -0.9966 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B12 compound treatment 326520.0 -54000.0 -0.36 366660.0 -25300.0 -0.18 -0.3874 -0.9494 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B13 mock treatment 414170.0 33700.0 0.23 387970.0 -4010.0 -0.03 0.1405 0.612 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B14 mock treatment 381000.0 526.0 0.0 425940.0 34000.0 0.25 0.1763 0.7173 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B15 compound treatment 427000.0 46500.0 0.31 354130.0 -37900.0 -0.27 0.0285 0.0685 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B16 compound treatment 279810.0 -101000.0 -0.68 306680.0 -85300.0 -0.62 -0.9176 -0.9988 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B17 compound treatment 78460.0 -302000.0 -2.04 112580.0 -279000.0 -2.02 -2.8731 -1.0 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B18 compound treatment 259150.0 -121000.0 -0.82 317380.0 -74600.0 -0.54 -0.9615 -0.9795 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B19 compound treatment 192020.0 -188000.0 -1.27 235200.0 -157000.0 -1.13 -1.7029 -0.9984 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B20 compound treatment 198130.0 -182000.0 -1.23 187870.0 -204000.0 -1.48 -1.916 -0.9959 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B21 compound treatment 227460.0 -153000.0 -1.03 321600.0 -70400.0 -0.51 -1.0913 -0.9468 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B22 compound treatment 285280.0 -95200.0 -0.64 326080.0 -65900.0 -0.48 -0.7921 -0.9892 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B23 compound treatment 310840.0 -69600.0 -0.47 210650.0 -181000.0 -1.31 -1.2609 -0.9042 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 B24 compound treatment 185290.0 -195000.0 -1.32 178010.0 -214000.0 -1.55 -2.0278 -0.9968 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C01 compound treatment 58560.0 -322000.0 -2.18 68560.0 -323000.0 -2.34 -3.1935 -0.9993 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C02 compound treatment 119810.0 -261000.0 -1.76 169370.0 -223000.0 -1.61 -2.3849 -0.999 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C03 compound treatment 197140.0 -183000.0 -1.24 257280.0 -135000.0 -0.98 -1.5654 -0.993 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C04 compound treatment 200820.0 -180000.0 -1.21 188520.0 -203000.0 -1.47 -1.8998 -0.9954 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C05 compound treatment 279040.0 -101000.0 -0.69 385280.0 -6700.0 -0.05 -0.5189 -0.7553 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C06 compound treatment 250210.0 -130000.0 -0.88 270760.0 -121000.0 -0.88 -1.2429 -1.0 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C07 compound treatment 286150.0 -94300.0 -0.64 291920.0 -100000.0 -0.72 -0.9628 -0.998 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C08 compound treatment 296240.0 -84200.0 -0.57 286990.0 -105000.0 -0.76 -0.9399 -0.9898 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C09 compound treatment 332320.0 -48200.0 -0.33 311890.0 -80100.0 -0.58 -0.64 -0.9627 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C10 compound treatment 108590.0 -272000.0 -1.84 232580.0 -159000.0 -1.15 -2.1149 -0.9749 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C11 mock treatment 319560.0 -60900.0 -0.41 449060.0 57100.0 0.41 0.0011 0.002 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C12 mock treatment 320280.0 -60200.0 -0.41 363680.0 -28300.0 -0.2 -0.4325 -0.9496 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C13 compound treatment 85710.0 -295000.0 -1.99 121440.0 -271000.0 -1.96 -2.7931 -1.0 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C14 compound treatment 201310.0 -179000.0 -1.21 203070.0 -189000.0 -1.37 -1.823 -0.9982 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C15 mock treatment 325990.0 -54500.0 -0.37 383260.0 -8720.0 -0.06 -0.3049 -0.8164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C16 mock treatment 287530.0 -92900.0 -0.63 353170.0 -38800.0 -0.28 -0.6427 -0.9342 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C17 compound treatment 103150.0 -277000.0 -1.87 140010.0 -252000.0 -1.82 -2.6148 -0.9999 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C18 compound treatment 156160.0 -224000.0 -1.52 193720.0 -198000.0 -1.44 -2.0866 -0.9996 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C19 compound treatment 110400.0 -270000.0 -1.82 142430.0 -250000.0 -1.81 -2.5677 -1.0 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C20 compound treatment 150520.0 -230000.0 -1.55 181220.0 -211000.0 -1.53 -2.1775 -1.0 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C21 compound treatment 320400.0 -60100.0 -0.41 244750.0 -147000.0 -1.07 -1.0406 -0.9125 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C22 compound treatment 223120.0 -157000.0 -1.06 224420.0 -168000.0 -1.21 -1.6095 -0.9978 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C23 compound treatment 366920.0 -13600.0 -0.09 301660.0 -90300.0 -0.65 -0.5271 -0.7984 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 C24 compound treatment 222050.0 -158000.0 -1.07 214530.0 -177000.0 -1.28 -1.6652 -0.9959 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D01 compound treatment 276970.0 -104000.0 -0.7 367600.0 -24400.0 -0.18 -0.6193 -0.8586 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D02 compound treatment 262240.0 -118000.0 -0.8 295910.0 -96100.0 -0.7 -1.0567 -0.9976 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D03 compound treatment 355580.0 -24900.0 -0.17 266470.0 -126000.0 -0.91 -0.7614 -0.824 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D04 compound treatment 177650.0 -203000.0 -1.37 198310.0 -194000.0 -1.4 -1.9604 -0.9999 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D05 compound treatment 155650.0 -225000.0 -1.52 157170.0 -235000.0 -1.7 -2.2761 -0.9984 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D06 compound treatment 99210.0 -281000.0 -1.9 253600.0 -138000.0 -1.0 -2.0521 -0.9552 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D07 compound treatment 322730.0 -57700.0 -0.39 355040.0 -36900.0 -0.27 -0.465 -0.983 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D08 compound treatment 45180.0 -335000.0 -2.27 123230.0 -269000.0 -1.95 -2.9776 -0.9971 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D09 compound treatment 189680.0 -191000.0 -1.29 216320.0 -176000.0 -1.27 -1.8107 -1.0 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D10 compound treatment 377800.0 -2670.0 -0.02 373850.0 -18100.0 -0.13 -0.1056 -0.7969 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D11 mock treatment 438680.0 58200.0 0.39 452540.0 60600.0 0.44 0.5881 0.9985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D12 mock treatment 429600.0 49100.0 0.33 374310.0 -17700.0 -0.13 0.1443 0.4056 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D13 compound treatment 202080.0 -178000.0 -1.21 208520.0 -183000.0 -1.33 -1.7914 -0.9988 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D14 compound treatment 181320.0 -199000.0 -1.35 252710.0 -139000.0 -1.01 -1.6644 -0.9899 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D15 mock treatment 404030.0 23600.0 0.16 379060.0 -12900.0 -0.09 0.0464 0.2514 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D16 mock treatment 408550.0 28100.0 0.19 403040.0 11100.0 0.08 0.1908 0.9264 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D17 compound treatment 360500.0 -20000.0 -0.13 357830.0 -34200.0 -0.25 -0.2702 -0.9595 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D18 compound treatment 320160.0 -60300.0 -0.41 303170.0 -88800.0 -0.64 -0.7428 -0.9758 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D19 compound treatment 359260.0 -21200.0 -0.14 309380.0 -82600.0 -0.6 -0.5242 -0.8525 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D20 compound treatment 252660.0 -128000.0 -0.86 284530.0 -107000.0 -0.78 -1.1607 -0.9986 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D21 compound treatment 190960.0 -190000.0 -1.28 196480.0 -196000.0 -1.42 -1.9062 -0.9988 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D22 compound treatment 230880.0 -150000.0 -1.01 283680.0 -108000.0 -0.78 -1.2691 -0.9921 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D23 compound treatment 165840.0 -215000.0 -1.45 164250.0 -228000.0 -1.65 -2.1912 -0.998 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 D24 compound treatment 142740.0 -238000.0 -1.61 199390.0 -193000.0 -1.39 -2.1217 -0.9975 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E01 mock treatment 308590.0 -71900.0 -0.49 456640.0 64700.0 0.47 -0.0125 -0.0185 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E02 mock treatment 346490.0 -34000.0 -0.23 448990.0 57000.0 0.41 0.1294 0.2741 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E03 compound treatment 229530.0 -151000.0 -1.02 348360.0 -43600.0 -0.32 -0.9445 -0.8846 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E04 compound treatment 134810.0 -246000.0 -1.66 336810.0 -55200.0 -0.4 -1.4561 -0.8529 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E05 compound treatment 403930.0 23500.0 0.16 381560.0 -10400.0 -0.08 0.0587 0.3346 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E06 compound treatment 394640.0 14200.0 0.1 413140.0 21200.0 0.15 0.176 0.9744 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E07 compound treatment 68350.0 -312000.0 -2.11 201470.0 -191000.0 -1.38 -2.4664 -0.9788 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E08 compound treatment 224550.0 -156000.0 -1.05 266800.0 -125000.0 -0.91 -1.3857 -0.9972 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E09 mock treatment 241920.0 -139000.0 -0.94 392200.0 220.0 0.0 -0.6609 -0.7059 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E10 mock treatment 346590.0 -33900.0 -0.23 374010.0 -18000.0 -0.13 -0.2539 -0.9641 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E11 compound treatment 300910.0 -79600.0 -0.54 284400.0 -108000.0 -0.78 -0.9308 -0.9836 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E12 compound treatment 197250.0 -183000.0 -1.24 252640.0 -139000.0 -1.01 -1.5886 -0.9948 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E13 compound treatment 235200.0 -145000.0 -0.98 287130.0 -105000.0 -0.76 -1.2308 -0.9919 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E14 compound treatment 219810.0 -161000.0 -1.09 290180.0 -102000.0 -0.74 -1.2887 -0.9822 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E15 compound treatment 255570.0 -125000.0 -0.84 259050.0 -133000.0 -0.96 -1.2772 -0.9979 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E16 compound treatment 181650.0 -199000.0 -1.34 233880.0 -158000.0 -1.14 -1.7592 -0.9968 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E17 mock treatment 397520.0 17000.0 0.12 402240.0 10300.0 0.07 0.134 0.9775 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E18 mock treatment 321860.0 -58600.0 -0.4 340480.0 -51500.0 -0.37 -0.5437 -0.9995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E19 compound treatment 368080.0 -12400.0 -0.08 347530.0 -44500.0 -0.32 -0.2867 -0.8624 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E20 compound treatment 189800.0 -191000.0 -1.29 229700.0 -162000.0 -1.17 -1.7417 -0.9989 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E21 compound treatment 252750.0 -128000.0 -0.86 349990.0 -42000.0 -0.3 -0.8252 -0.9019 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E22 compound treatment 258250.0 -122000.0 -0.83 230080.0 -162000.0 -1.17 -1.4127 -0.9853 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E23 compound treatment 193520.0 -187000.0 -1.26 218130.0 -174000.0 -1.26 -1.7831 -1.0 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 E24 compound treatment 193690.0 -187000.0 -1.26 205510.0 -186000.0 -1.35 -1.8469 -0.9994 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F01 mock treatment 325960.0 -54500.0 -0.37 408660.0 16700.0 0.12 -0.1751 -0.4517 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F02 mock treatment 401990.0 21500.0 0.15 324830.0 -67200.0 -0.49 -0.2409 -0.4748 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F03 compound treatment 201250.0 -179000.0 -1.21 219880.0 -172000.0 -1.25 -1.7372 -0.9999 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F04 compound treatment 130640.0 -250000.0 -1.69 168000.0 -224000.0 -1.62 -2.3401 -0.9998 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F05 compound treatment 167130.0 -213000.0 -1.44 185230.0 -207000.0 -1.5 -2.0776 -0.9998 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F06 compound treatment 234720.0 -146000.0 -0.98 367360.0 -24600.0 -0.18 -0.8224 -0.8217 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F07 compound treatment 215730.0 -165000.0 -1.11 288160.0 -104000.0 -0.75 -1.3185 -0.9817 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F08 compound treatment 153300.0 -227000.0 -1.53 270460.0 -122000.0 -0.88 -1.7074 -0.9651 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F09 mock treatment 354840.0 -25600.0 -0.17 373070.0 -18900.0 -0.14 -0.2193 -0.9932 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F10 mock treatment 362430.0 -18000.0 -0.12 448560.0 56600.0 0.41 0.2034 0.476 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F11 compound treatment 297060.0 -83400.0 -0.56 250240.0 -142000.0 -1.03 -1.1241 -0.9602 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F12 compound treatment 347330.0 -33100.0 -0.22 352180.0 -39800.0 -0.29 -0.3621 -0.9922 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F13 compound treatment 265390.0 -115000.0 -0.78 250720.0 -141000.0 -1.02 -1.2729 -0.9909 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F14 compound treatment 247520.0 -133000.0 -0.9 232860.0 -159000.0 -1.15 -1.4497 -0.9924 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F15 compound treatment 165570.0 -215000.0 -1.45 143680.0 -248000.0 -1.8 -2.2977 -0.9944 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F16 compound treatment 243480.0 -137000.0 -0.93 240680.0 -151000.0 -1.1 -1.429 -0.9965 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F17 mock treatment 421730.0 41300.0 0.28 385960.0 -6020.0 -0.04 0.1663 0.5894 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F18 mock treatment 413540.0 33100.0 0.22 323250.0 -68700.0 -0.5 -0.1938 -0.3554 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F19 compound treatment 228810.0 -152000.0 -1.02 233950.0 -158000.0 -1.14 -1.5335 -0.9985 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F20 compound treatment 347460.0 -33000.0 -0.22 376170.0 -15800.0 -0.11 -0.2387 -0.9519 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F21 compound treatment 368480.0 -12000.0 -0.08 362030.0 -30000.0 -0.22 -0.2106 -0.9099 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F22 compound treatment 426450.0 46000.0 0.31 284340.0 -108000.0 -0.78 -0.3313 -0.395 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F23 compound treatment 267770.0 -113000.0 -0.76 215360.0 -177000.0 -1.28 -1.4425 -0.9694 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 F24 compound treatment 338340.0 -42100.0 -0.28 256400.0 -136000.0 -0.98 -0.8953 -0.8761 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G01 compound treatment 349070.0 -31400.0 -0.21 282190.0 -110000.0 -0.79 -0.712 -0.8656 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G02 compound treatment 220390.0 -160000.0 -1.08 256890.0 -135000.0 -0.98 -1.4563 -0.9987 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G03 mock treatment 460370.0 79900.0 0.54 361760.0 -30200.0 -0.22 0.227 0.3898 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G04 mock treatment 386500.0 6030.0 0.04 397600.0 5620.0 0.04 0.0576 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G05 compound treatment 310150.0 -70300.0 -0.48 372740.0 -19200.0 -0.14 -0.4345 -0.8775 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G06 compound treatment 272960.0 -108000.0 -0.73 270560.0 -121000.0 -0.88 -1.1352 -0.9955 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G07 compound treatment 267520.0 -113000.0 -0.76 326680.0 -65300.0 -0.47 -0.8739 -0.9735 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G08 compound treatment 308480.0 -72000.0 -0.49 370040.0 -21900.0 -0.16 -0.4563 -0.8917 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G09 compound treatment 367940.0 -12500.0 -0.08 422450.0 30500.0 0.22 0.0961 0.4067 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G10 compound treatment 241780.0 -139000.0 -0.94 333710.0 -58300.0 -0.42 -0.9609 -0.935 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G11 compound treatment 330400.0 -50100.0 -0.34 187840.0 -204000.0 -1.48 -1.2842 -0.8471 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G12 compound treatment 84260.0 -296000.0 -2.0 159600.0 -232000.0 -1.68 -2.6047 -0.9963 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G13 compound treatment 98200.0 -282000.0 -1.91 109370.0 -283000.0 -2.05 -2.7952 -0.9994 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G14 compound treatment 478800.0 98300.0 0.66 369620.0 -22400.0 -0.16 0.3553 0.5196 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G15 compound treatment 508090.0 128000.0 0.86 398480.0 6500.0 0.05 0.643 0.7446 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G16 compound treatment 234720.0 -146000.0 -0.98 250930.0 -141000.0 -1.02 -1.4184 -0.9998 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G17 compound treatment 314400.0 -66100.0 -0.45 360050.0 -31900.0 -0.23 -0.4791 -0.953 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G18 compound treatment 219440.0 -161000.0 -1.09 216710.0 -175000.0 -1.27 -1.6665 -0.9971 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G19 mock treatment 401440.0 21000.0 0.14 362090.0 -29900.0 -0.22 -0.0528 -0.2043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G20 mock treatment 363150.0 -17300.0 -0.12 392250.0 270.0 0.0 -0.0814 -0.6952 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G21 compound treatment 432040.0 51600.0 0.35 443290.0 51300.0 0.37 0.509 0.9995 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G22 compound treatment 130720.0 -250000.0 -1.69 180560.0 -211000.0 -1.53 -2.2755 -0.9988 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G23 compound treatment 247600.0 -133000.0 -0.9 296860.0 -95100.0 -0.69 -1.1217 -0.9914 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 G24 compound treatment 113080.0 -267000.0 -1.81 148020.0 -244000.0 -1.77 -2.5263 -0.9999 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H01 compound treatment 160880.0 -220000.0 -1.48 166960.0 -225000.0 -1.63 -2.201 -0.9989 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H02 compound treatment 214440.0 -166000.0 -1.12 342600.0 -49400.0 -0.36 -1.046 -0.8884 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H03 mock treatment 474580.0 94100.0 0.64 408230.0 16300.0 0.12 0.5328 0.8239 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H04 mock treatment 305920.0 -74600.0 -0.5 473370.0 81400.0 0.59 0.0604 0.0779 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H05 compound treatment 202930.0 -178000.0 -1.2 254890.0 -137000.0 -0.99 -1.55 -0.9956 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H06 compound treatment 290460.0 -90000.0 -0.61 299810.0 -92200.0 -0.67 -0.9019 -0.9989 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H07 compound treatment 242260.0 -138000.0 -0.93 300120.0 -91900.0 -0.66 -1.1306 -0.9861 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H08 compound treatment 291860.0 -88600.0 -0.6 463520.0 71500.0 0.52 -0.0572 -0.0722 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H09 compound treatment 197820.0 -183000.0 -1.23 232610.0 -159000.0 -1.15 -1.6885 -0.9994 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H10 compound treatment 308480.0 -72000.0 -0.49 284670.0 -107000.0 -0.78 -0.8933 -0.9746 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H11 compound treatment 284730.0 -95700.0 -0.65 262720.0 -129000.0 -0.94 -1.1191 -0.9838 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H12 compound treatment 217240.0 -163000.0 -1.1 211740.0 -180000.0 -1.3 -1.7025 -0.9965 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H13 compound treatment 164640.0 -216000.0 -1.46 241990.0 -150000.0 -1.09 -1.799 -0.9894 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H14 compound treatment 114570.0 -266000.0 -1.8 181280.0 -211000.0 -1.53 -2.3489 -0.9967 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H15 compound treatment 142110.0 -238000.0 -1.61 196110.0 -196000.0 -1.42 -2.1415 -0.998 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H16 compound treatment 359580.0 -20900.0 -0.14 295620.0 -96400.0 -0.7 -0.5931 -0.8333 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H17 compound treatment 432090.0 51600.0 0.35 323910.0 -68100.0 -0.49 -0.1018 -0.1687 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H18 compound treatment 362370.0 -18100.0 -0.12 314500.0 -77500.0 -0.56 -0.4831 -0.8415 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H19 mock treatment 289210.0 -91300.0 -0.62 406360.0 14400.0 0.1 -0.3624 -0.5795 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H20 mock treatment 493090.0 113000.0 0.76 358360.0 -33600.0 -0.24 0.366 0.4581 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H21 compound treatment 159970.0 -221000.0 -1.49 167640.0 -224000.0 -1.62 -2.2019 -0.9991 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H22 compound treatment 167230.0 -213000.0 -1.44 294880.0 -97100.0 -0.7 -1.5159 -0.9455 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H23 compound treatment 168380.0 -212000.0 -1.43 179170.0 -213000.0 -1.54 -2.1027 -0.9993 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 H24 compound treatment 142200.0 -238000.0 -1.61 185530.0 -206000.0 -1.49 -2.1952 -0.9993 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I01 compound treatment 262400.0 -118000.0 -0.8 312110.0 -79900.0 -0.58 -0.973 -0.9875 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I02 compound treatment 134320.0 -246000.0 -1.66 179540.0 -212000.0 -1.54 -2.2635 -0.9992 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I03 compound treatment 195290.0 -185000.0 -1.25 214440.0 -178000.0 -1.29 -1.7935 -0.9999 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I04 compound treatment 180270.0 -200000.0 -1.35 285890.0 -106000.0 -0.77 -1.4996 -0.964 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I05 mock treatment 396720.0 16200.0 0.11 508800.0 117000.0 0.85 0.6756 0.7922 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I06 mock treatment 406600.0 26100.0 0.18 470030.0 78100.0 0.56 0.5243 0.8858 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I07 compound treatment 219410.0 -161000.0 -1.09 204200.0 -188000.0 -1.36 -1.7307 -0.9939 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I08 compound treatment 445760.0 65300.0 0.44 298730.0 -93300.0 -0.68 -0.1654 -0.2051 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I09 compound treatment 405630.0 25200.0 0.17 296480.0 -95500.0 -0.69 -0.3686 -0.5178 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I10 compound treatment 252010.0 -128000.0 -0.87 303680.0 -88300.0 -0.64 -1.0658 -0.9887 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I11 compound treatment 347520.0 -33000.0 -0.22 388260.0 -3720.0 -0.03 -0.1765 -0.7869 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I12 compound treatment 173180.0 -207000.0 -1.4 207240.0 -185000.0 -1.34 -1.936 -0.9997 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I13 compound treatment 393820.0 13300.0 0.09 484510.0 92500.0 0.67 0.5374 0.7951 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I14 compound treatment 189400.0 -191000.0 -1.29 266560.0 -125000.0 -0.91 -1.5549 -0.9852 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I15 compound treatment 421880.0 41400.0 0.28 457700.0 65700.0 0.48 0.5342 0.968 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I16 compound treatment 134560.0 -246000.0 -1.66 205640.0 -186000.0 -1.35 -2.1287 -0.9946 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I17 compound treatment 428200.0 47700.0 0.32 406180.0 14200.0 0.1 0.3007 0.8885 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I18 compound treatment 366520.0 -14000.0 -0.09 385470.0 -6510.0 -0.05 -0.1 -0.9486 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I19 compound treatment 229760.0 -151000.0 -1.02 224180.0 -168000.0 -1.21 -1.579 -0.9962 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I20 compound treatment 168290.0 -212000.0 -1.43 198730.0 -193000.0 -1.4 -2.003 -0.9999 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I21 mock treatment 439600.0 59100.0 0.4 439060.0 47100.0 0.34 0.5235 0.9969 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I22 mock treatment 452000.0 71500.0 0.48 339770.0 -52200.0 -0.38 0.0745 0.1214 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I23 compound treatment 235200.0 -145000.0 -0.98 328400.0 -63600.0 -0.46 -1.0195 -0.9404 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 I24 compound treatment 205250.0 -175000.0 -1.18 244250.0 -148000.0 -1.07 -1.5934 -0.9987 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J01 compound treatment 52750.0 -328000.0 -2.21 92320.0 -300000.0 -2.17 -3.0997 -0.9999 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J02 compound treatment 162040.0 -218000.0 -1.48 177840.0 -214000.0 -1.55 -2.1398 -0.9997 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J03 compound treatment 174100.0 -206000.0 -1.39 218160.0 -174000.0 -1.26 -1.8757 -0.9987 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J04 compound treatment 395420.0 14900.0 0.1 405230.0 13300.0 0.1 0.1392 0.9997 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J05 mock treatment 399270.0 18800.0 0.13 324270.0 -67700.0 -0.49 -0.2568 -0.5071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J06 mock treatment 400030.0 19600.0 0.13 242080.0 -150000.0 -1.09 -0.6739 -0.6164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J07 compound treatment 153840.0 -227000.0 -1.53 157050.0 -235000.0 -1.7 -2.2853 -0.9986 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J08 compound treatment 169280.0 -211000.0 -1.43 246660.0 -145000.0 -1.05 -1.7529 -0.9887 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J09 compound treatment 276090.0 -104000.0 -0.71 272690.0 -119000.0 -0.86 -1.1093 -0.995 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J10 compound treatment 209790.0 -171000.0 -1.15 221300.0 -171000.0 -1.24 -1.6892 -0.9994 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J11 compound treatment 169770.0 -211000.0 -1.42 171360.0 -221000.0 -1.6 -2.136 -0.9984 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J12 compound treatment 359300.0 -21200.0 -0.14 502400.0 110000.0 0.8 0.464 0.5715 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J13 compound treatment 93380.0 -287000.0 -1.94 132480.0 -260000.0 -1.88 -2.7 -0.9999 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J14 compound treatment 40420.0 -340000.0 -2.3 82890.0 -309000.0 -2.24 -3.2068 -0.9999 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J15 compound treatment 315130.0 -65300.0 -0.44 394400.0 2420.0 0.02 -0.2998 -0.6785 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J16 compound treatment 336120.0 -44400.0 -0.3 379290.0 -12700.0 -0.09 -0.2769 -0.8833 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J17 compound treatment 343270.0 -37200.0 -0.25 342130.0 -49900.0 -0.36 -0.4329 -0.9844 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J18 compound treatment 44440.0 -336000.0 -2.27 96830.0 -295000.0 -2.14 -3.1163 -0.9995 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J19 compound treatment 299200.0 -81300.0 -0.55 357810.0 -34200.0 -0.25 -0.5632 -0.9351 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J20 compound treatment 137400.0 -243000.0 -1.64 230050.0 -162000.0 -1.17 -1.9902 -0.9863 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J21 mock treatment 350580.0 -29900.0 -0.2 412580.0 20600.0 0.15 -0.0374 -0.1489 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J22 mock treatment 339200.0 -41300.0 -0.28 187790.0 -204000.0 -1.48 -1.2424 -0.8259 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J23 compound treatment 282160.0 -98300.0 -0.66 271520.0 -120000.0 -0.87 -1.0863 -0.991 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 J24 compound treatment 75650.0 -305000.0 -2.06 129410.0 -263000.0 -1.9 -2.8004 -0.9992 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K01 compound treatment 231080.0 -149000.0 -1.01 392860.0 880.0 0.01 -0.7093 -0.7026 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K02 compound treatment 236400.0 -144000.0 -0.97 173010.0 -219000.0 -1.59 -1.8092 -0.9726 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K03 compound treatment 231680.0 -149000.0 -1.01 353570.0 -38400.0 -0.28 -0.9075 -0.87 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K04 compound treatment 166080.0 -214000.0 -1.45 238510.0 -153000.0 -1.11 -1.8099 -0.9914 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K05 compound treatment 272040.0 -108000.0 -0.73 234400.0 -158000.0 -1.14 -1.3247 -0.9771 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K06 compound treatment 178910.0 -202000.0 -1.36 244980.0 -147000.0 -1.06 -1.7155 -0.9925 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K07 mock treatment 282170.0 -98300.0 -0.66 406560.0 14600.0 0.11 -0.395 -0.5874 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K08 mock treatment 434310.0 53800.0 0.36 486440.0 94500.0 0.68 0.7407 0.9564 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K09 compound treatment 329480.0 -51000.0 -0.34 467080.0 75100.0 0.54 0.1408 0.2187 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K10 compound treatment 248080.0 -132000.0 -0.89 346810.0 -45200.0 -0.33 -0.8638 -0.9069 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K11 compound treatment 292730.0 -87700.0 -0.59 260560.0 -131000.0 -0.95 -1.0919 -0.9741 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K12 compound treatment 204130.0 -176000.0 -1.19 452640.0 60700.0 0.44 -0.532 -0.419 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K13 compound treatment 394310.0 13800.0 0.09 422290.0 30300.0 0.22 0.2213 0.9277 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K14 compound treatment 351860.0 -28600.0 -0.19 278410.0 -114000.0 -0.82 -0.718 -0.8502 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K15 mock treatment 274240.0 -106000.0 -0.72 318770.0 -73200.0 -0.53 -0.8823 -0.9889 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K16 mock treatment 495560.0 115000.0 0.78 368660.0 -23300.0 -0.17 0.4305 0.541 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K17 compound treatment 346110.0 -34400.0 -0.23 509490.0 118000.0 0.85 0.4373 0.496 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K18 compound treatment 249560.0 -131000.0 -0.88 306130.0 -85900.0 -0.62 -1.0649 -0.9851 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K19 compound treatment 56590.0 -324000.0 -2.19 119520.0 -272000.0 -1.97 -2.9421 -0.9987 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K20 compound treatment 150290.0 -230000.0 -1.56 200280.0 -192000.0 -1.39 -2.081 -0.9984 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K21 compound treatment 486470.0 106000.0 0.72 427940.0 36000.0 0.26 0.6905 0.9061 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K22 compound treatment 118240.0 -262000.0 -1.77 161600.0 -230000.0 -1.67 -2.4321 -0.9995 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K23 mock treatment 281480.0 -99000.0 -0.67 321340.0 -70600.0 -0.51 -0.8346 -0.9912 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 K24 mock treatment 275300.0 -105000.0 -0.71 323250.0 -68700.0 -0.5 -0.8543 -0.9848 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L01 compound treatment 145280.0 -235000.0 -1.59 160580.0 -231000.0 -1.68 -2.3082 -0.9997 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L02 compound treatment 271400.0 -109000.0 -0.74 209600.0 -182000.0 -1.32 -1.4547 -0.9621 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L03 compound treatment 193250.0 -187000.0 -1.27 251040.0 -141000.0 -1.02 -1.6159 -0.9943 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L04 compound treatment 192180.0 -188000.0 -1.27 237140.0 -155000.0 -1.12 -1.6922 -0.998 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L05 compound treatment 154240.0 -226000.0 -1.53 164820.0 -227000.0 -1.64 -2.2437 -0.9993 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L06 compound treatment 192480.0 -188000.0 -1.27 328490.0 -63500.0 -0.46 -1.2232 -0.9055 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L07 mock treatment 459920.0 79400.0 0.54 413780.0 21800.0 0.16 0.4912 0.8778 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L08 mock treatment 241460.0 -139000.0 -0.94 449920.0 57900.0 0.42 -0.3676 -0.3574 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L09 compound treatment 179300.0 -201000.0 -1.36 468210.0 76200.0 0.55 -0.571 -0.3892 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L10 compound treatment 487730.0 107000.0 0.72 514110.0 122000.0 0.88 1.1376 0.9951 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L11 compound treatment 168530.0 -212000.0 -1.43 240870.0 -151000.0 -1.09 -1.7861 -0.9912 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L12 compound treatment 342020.0 -38500.0 -0.26 265950.0 -126000.0 -0.91 -0.8288 -0.8737 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L13 compound treatment 147070.0 -233000.0 -1.58 239400.0 -153000.0 -1.1 -1.8962 -0.9848 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L14 compound treatment 65510.0 -315000.0 -2.13 186560.0 -205000.0 -1.49 -2.5563 -0.9846 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L15 mock treatment 519930.0 139000.0 0.94 500030.0 108000.0 0.78 1.2194 0.9957 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L16 mock treatment 409030.0 28600.0 0.19 485920.0 93900.0 0.68 0.6173 0.8733 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L17 compound treatment 306280.0 -74200.0 -0.5 236920.0 -155000.0 -1.12 -1.1482 -0.934 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L18 compound treatment 70850.0 -310000.0 -2.09 182560.0 -209000.0 -1.52 -2.5513 -0.9875 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L19 compound treatment 257710.0 -123000.0 -0.83 315750.0 -76200.0 -0.55 -0.9767 -0.9804 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L20 compound treatment 216860.0 -164000.0 -1.11 333610.0 -58400.0 -0.42 -1.0805 -0.913 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L21 compound treatment 227720.0 -153000.0 -1.03 371580.0 -20400.0 -0.15 -0.8343 -0.8001 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L22 compound treatment 163270.0 -217000.0 -1.47 294560.0 -97400.0 -0.71 -1.5364 -0.9436 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L23 mock treatment 361680.0 -18800.0 -0.13 461150.0 69200.0 0.5 0.2643 0.5116 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 L24 mock treatment 335200.0 -45300.0 -0.31 422010.0 30000.0 0.22 -0.0626 -0.1668 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M01 compound treatment 194080.0 -186000.0 -1.26 256400.0 -136000.0 -0.98 -1.5845 -0.9924 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M02 compound treatment 263620.0 -117000.0 -0.79 203440.0 -189000.0 -1.36 -1.5234 -0.9662 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M03 compound treatment 325070.0 -55400.0 -0.37 389220.0 -2760.0 -0.02 -0.2788 -0.7438 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M04 compound treatment 320190.0 -60300.0 -0.41 279840.0 -112000.0 -0.81 -0.862 -0.9491 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M05 compound treatment 252000.0 -128000.0 -0.87 422500.0 30500.0 0.22 -0.4576 -0.5109 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M06 compound treatment 271210.0 -109000.0 -0.74 228860.0 -163000.0 -1.18 -1.357 -0.9744 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M07 compound treatment 402720.0 22200.0 0.15 243680.0 -148000.0 -1.07 -0.6528 -0.6022 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M08 compound treatment 202610.0 -178000.0 -1.2 222300.0 -170000.0 -1.23 -1.7183 -0.9999 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M09 mock treatment 357440.0 -23000.0 -0.16 490960.0 99000.0 0.72 0.3966 0.5409 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M10 mock treatment 493360.0 113000.0 0.76 511920.0 120000.0 0.87 1.1533 0.9979 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M11 compound treatment 438450.0 58000.0 0.39 490610.0 98600.0 0.71 0.7819 0.9601 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M12 compound treatment 173370.0 -207000.0 -1.4 174960.0 -217000.0 -1.57 -2.1004 -0.9983 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M13 mock treatment 427060.0 46600.0 0.31 364400.0 -27600.0 -0.2 0.0814 0.2184 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M14 mock treatment 468800.0 88300.0 0.6 524120.0 132000.0 0.96 1.0984 0.9742 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M15 compound treatment 269820.0 -111000.0 -0.75 341920.0 -50100.0 -0.36 -0.7849 -0.9447 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M16 compound treatment 486240.0 106000.0 0.71 517850.0 126000.0 0.91 1.1496 0.9928 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M17 compound treatment 331170.0 -49300.0 -0.33 397380.0 5400.0 0.04 -0.2079 -0.6199 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M18 compound treatment 224640.0 -156000.0 -1.05 250130.0 -142000.0 -1.03 -1.4706 -0.9999 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M19 compound treatment 410350.0 29900.0 0.2 413600.0 21600.0 0.16 0.2534 0.9921 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M20 compound treatment 342240.0 -38200.0 -0.26 335310.0 -56700.0 -0.41 -0.4728 -0.9752 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M21 compound treatment 391840.0 11400.0 0.08 467630.0 75700.0 0.55 0.4415 0.7985 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M22 compound treatment 317040.0 -63400.0 -0.43 202660.0 -189000.0 -1.37 -1.2721 -0.8859 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M23 compound treatment 9440.0 -371000.0 -2.51 11760.0 -380000.0 -2.75 -3.719 -0.9989 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 M24 compound treatment 131040.0 -249000.0 -1.69 204130.0 -188000.0 -1.36 -2.1533 -0.9943 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N01 compound treatment 173320.0 -207000.0 -1.4 216760.0 -175000.0 -1.27 -1.8866 -0.9988 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N02 compound treatment 232850.0 -148000.0 -1.0 210400.0 -182000.0 -1.31 -1.6348 -0.9907 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N03 compound treatment 161650.0 -219000.0 -1.48 296760.0 -95200.0 -0.69 -1.5329 -0.9397 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N04 compound treatment 328520.0 -52000.0 -0.35 360930.0 -31100.0 -0.22 -0.4072 -0.9768 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N05 compound treatment 183240.0 -197000.0 -1.33 258340.0 -134000.0 -0.97 -1.6264 -0.9876 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N06 compound treatment 358310.0 -22200.0 -0.15 315080.0 -76900.0 -0.56 -0.4995 -0.8665 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N07 compound treatment 133060.0 -247000.0 -1.67 152380.0 -240000.0 -1.73 -2.4085 -0.9998 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N08 compound treatment 58310.0 -322000.0 -2.18 122400.0 -270000.0 -1.95 -2.9191 -0.9985 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N09 mock treatment 303040.0 -77400.0 -0.52 348050.0 -43900.0 -0.32 -0.5948 -0.9715 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N10 mock treatment 515870.0 135000.0 0.91 484100.0 92100.0 0.67 1.1184 0.9879 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N11 compound treatment 157440.0 -223000.0 -1.51 133850.0 -258000.0 -1.87 -2.3869 -0.9943 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N12 compound treatment 243480.0 -137000.0 -0.93 244970.0 -147000.0 -1.06 -1.407 -0.9976 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N13 mock treatment 435040.0 54600.0 0.37 319550.0 -72400.0 -0.52 -0.11 -0.1717 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N14 mock treatment 493450.0 113000.0 0.76 426690.0 34700.0 0.25 0.7174 0.8927 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N15 compound treatment 174300.0 -206000.0 -1.39 171400.0 -221000.0 -1.6 -2.1141 -0.9977 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N16 compound treatment 311090.0 -69400.0 -0.47 293450.0 -98500.0 -0.71 -0.8358 -0.9793 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N17 compound treatment 46240.0 -334000.0 -2.26 57930.0 -334000.0 -2.42 -3.3068 -0.9994 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N18 compound treatment 147360.0 -233000.0 -1.58 238620.0 -153000.0 -1.11 -1.8988 -0.9853 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N19 compound treatment 167250.0 -213000.0 -1.44 201410.0 -191000.0 -1.38 -1.9942 -0.9998 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N20 compound treatment 284190.0 -96300.0 -0.65 217290.0 -175000.0 -1.26 -1.3542 -0.9523 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N21 compound treatment 99840.0 -281000.0 -1.9 147860.0 -244000.0 -1.77 -2.5904 -0.9994 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N22 compound treatment 336170.0 -44300.0 -0.3 267380.0 -125000.0 -0.9 -0.8495 -0.8938 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N23 compound treatment 97310.0 -283000.0 -1.91 103570.0 -288000.0 -2.09 -2.8292 -0.9991 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 N24 compound treatment 130140.0 -250000.0 -1.69 122950.0 -269000.0 -1.95 -2.5731 -0.9975 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O01 compound treatment 203250.0 -177000.0 -1.2 160190.0 -232000.0 -1.68 -2.0332 -0.9863 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O02 compound treatment 95160.0 -285000.0 -1.93 159700.0 -232000.0 -1.68 -2.5521 -0.9977 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O03 compound treatment 138790.0 -242000.0 -1.63 167110.0 -225000.0 -1.63 -2.3058 -1.0 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O04 compound treatment 223950.0 -157000.0 -1.06 193140.0 -199000.0 -1.44 -1.7656 -0.9885 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O05 compound treatment 186280.0 -194000.0 -1.31 189440.0 -203000.0 -1.47 -1.9646 -0.9985 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O06 compound treatment 185960.0 -195000.0 -1.31 219220.0 -173000.0 -1.25 -1.8137 -0.9997 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O07 compound treatment 404960.0 24500.0 0.17 325940.0 -66000.0 -0.48 -0.2211 -0.437 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O08 compound treatment 124090.0 -256000.0 -1.73 138830.0 -253000.0 -1.83 -2.5208 -0.9996 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O09 compound treatment 58580.0 -322000.0 -2.17 113600.0 -278000.0 -2.02 -2.9629 -0.9993 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O10 compound treatment 195360.0 -185000.0 -1.25 208400.0 -184000.0 -1.33 -1.8241 -0.9995 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O11 mock treatment 469930.0 89500.0 0.6 290180.0 -102000.0 -0.74 -0.0937 -0.0983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O12 mock treatment 440640.0 60200.0 0.41 319530.0 -72500.0 -0.52 -0.0834 -0.1257 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O13 compound treatment 242580.0 -138000.0 -0.93 334240.0 -57700.0 -0.42 -0.9544 -0.9346 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O14 compound treatment 220280.0 -160000.0 -1.08 208920.0 -183000.0 -1.33 -1.7024 -0.995 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O15 compound treatment 220540.0 -160000.0 -1.08 311840.0 -80100.0 -0.58 -1.1743 -0.9575 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O16 compound treatment 155580.0 -225000.0 -1.52 197210.0 -195000.0 -1.41 -2.0715 -0.9993 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O17 compound treatment 116370.0 -264000.0 -1.78 195650.0 -196000.0 -1.42 -2.2668 -0.9936 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O18 compound treatment 175010.0 -205000.0 -1.39 185200.0 -207000.0 -1.5 -2.0401 -0.9993 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O19 compound treatment 53330.0 -327000.0 -2.21 59110.0 -333000.0 -2.41 -3.2669 -0.9991 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O20 compound treatment 186790.0 -194000.0 -1.31 180110.0 -212000.0 -1.53 -2.0099 -0.9969 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O21 compound treatment 5090.0 -375000.0 -2.54 8330.0 -384000.0 -2.78 -3.7573 -0.999 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O22 compound treatment 168400.0 -212000.0 -1.43 222050.0 -170000.0 -1.23 -1.8831 -0.9971 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O23 compound treatment 118120.0 -262000.0 -1.77 121180.0 -271000.0 -1.96 -2.6396 -0.9987 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 O24 compound treatment 125060.0 -255000.0 -1.73 158590.0 -233000.0 -1.69 -2.415 -0.9999 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P01 compound treatment 96110.0 -284000.0 -1.92 125490.0 -266000.0 -1.93 -2.7227 -1.0 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P02 compound treatment 8250.0 -372000.0 -2.52 10240.0 -382000.0 -2.76 -3.7324 -0.9989 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P03 compound treatment 74720.0 -306000.0 -2.07 96700.0 -295000.0 -2.14 -2.9723 -0.9999 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P04 compound treatment 22330.0 -358000.0 -2.42 24480.0 -368000.0 -2.66 -3.5923 -0.9989 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P05 compound treatment 33530.0 -347000.0 -2.34 52380.0 -340000.0 -2.46 -3.3959 -0.9997 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P06 compound treatment 52130.0 -328000.0 -2.22 91200.0 -301000.0 -2.18 -3.1084 -1.0 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P07 compound treatment 171140.0 -209000.0 -1.41 145760.0 -246000.0 -1.78 -2.2605 -0.9934 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P08 compound treatment 99690.0 -281000.0 -1.9 149400.0 -243000.0 -1.76 -2.5832 -0.9993 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P09 compound treatment 120340.0 -260000.0 -1.76 135520.0 -256000.0 -1.86 -2.5556 -0.9996 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P10 compound treatment 163790.0 -217000.0 -1.46 186760.0 -205000.0 -1.49 -2.0857 -1.0 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P11 mock treatment 280800.0 -99700.0 -0.67 263950.0 -128000.0 -0.93 -1.1316 -0.9877 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P12 mock treatment 247240.0 -133000.0 -0.9 218930.0 -173000.0 -1.25 -1.5224 -0.9869 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P13 compound treatment 59860.0 -321000.0 -2.17 89330.0 -303000.0 -2.19 -3.081 -1.0 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P14 compound treatment 123570.0 -257000.0 -1.74 153800.0 -238000.0 -1.72 -2.4466 -1.0 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P15 compound treatment 85190.0 -295000.0 -2.0 116070.0 -276000.0 -2.0 -2.8231 -1.0 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P16 compound treatment 200030.0 -180000.0 -1.22 187860.0 -204000.0 -1.48 -1.907 -0.9954 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P17 compound treatment 75520.0 -305000.0 -2.06 109300.0 -283000.0 -2.05 -2.904 -1.0 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P18 compound treatment 153120.0 -227000.0 -1.54 139040.0 -253000.0 -1.83 -2.381 -0.9962 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P19 compound treatment 24540.0 -356000.0 -2.4 45120.0 -347000.0 -2.51 -3.4761 -0.9998 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P20 compound treatment 2490.0 -378000.0 -2.55 4680.0 -387000.0 -2.8 -3.7884 -0.9989 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P21 compound treatment 14160.0 -366000.0 -2.48 28850.0 -363000.0 -2.63 -3.6089 -0.9995 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P22 compound treatment 147260.0 -233000.0 -1.58 186130.0 -206000.0 -1.49 -2.1679 -0.9996 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P23 compound treatment 147240.0 -233000.0 -1.58 164720.0 -227000.0 -1.65 -2.2776 -0.9998 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2093 P24 compound treatment 9620.0 -371000.0 -2.51 45470.0 -347000.0 -2.51 -3.5455 -1.0 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A01 compound treatment 220570.0 -157000.0 -1.06 222590.0 -129000.0 -0.93 -1.4095 -0.9979 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A02 compound treatment 97310.0 -280000.0 -1.89 131170.0 -220000.0 -1.59 -2.4664 -0.9963 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A03 compound treatment 231520.0 -146000.0 -0.99 169760.0 -182000.0 -1.31 -1.6276 -0.99 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A04 compound treatment 241980.0 -136000.0 -0.92 247270.0 -104000.0 -0.75 -1.1809 -0.9953 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A05 compound treatment 321790.0 -55800.0 -0.38 283460.0 -68000.0 -0.49 -0.6143 -0.9913 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A06 compound treatment 261120.0 -116000.0 -0.79 203230.0 -148000.0 -1.07 -1.3149 -0.9884 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A07 compound treatment 276550.0 -101000.0 -0.68 273730.0 -77700.0 -0.56 -0.8803 -0.9954 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A08 compound treatment 255720.0 -122000.0 -0.82 224990.0 -126000.0 -0.92 -1.2293 -0.9986 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A09 compound treatment 338410.0 -39200.0 -0.26 336510.0 -14900.0 -0.11 -0.2634 -0.9218 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A10 compound treatment 227960.0 -150000.0 -1.01 212180.0 -139000.0 -1.01 -1.4275 -1.0 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A11 compound treatment 100600.0 -277000.0 -1.87 115690.0 -236000.0 -1.71 -2.5299 -0.9989 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A12 compound treatment 187370.0 -190000.0 -1.29 184710.0 -167000.0 -1.21 -1.762 -0.9995 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A13 mock treatment 437760.0 60200.0 0.41 319880.0 -31500.0 -0.23 0.1262 0.2705 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A14 mock treatment 280260.0 -97300.0 -0.66 244160.0 -107000.0 -0.78 -1.0139 -0.9966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A15 compound treatment 289860.0 -87700.0 -0.59 257020.0 -94400.0 -0.68 -0.9022 -0.9975 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A16 compound treatment 184220.0 -193000.0 -1.31 169170.0 -182000.0 -1.32 -1.8566 -1.0 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A17 compound treatment 253660.0 -124000.0 -0.84 328540.0 -22900.0 -0.17 -0.7091 -0.8309 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A18 compound treatment 177610.0 -200000.0 -1.35 190520.0 -161000.0 -1.16 -1.7789 -0.9973 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A19 compound treatment 181960.0 -196000.0 -1.32 153810.0 -198000.0 -1.43 -1.946 -0.9992 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A20 compound treatment 215600.0 -162000.0 -1.09 208590.0 -143000.0 -1.03 -1.5049 -0.9996 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A21 compound treatment 236800.0 -141000.0 -0.95 281830.0 -69600.0 -0.5 -1.0287 -0.9558 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A22 compound treatment 275520.0 -102000.0 -0.69 403210.0 51800.0 0.37 -0.2224 -0.2834 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A23 compound treatment 247550.0 -130000.0 -0.88 229030.0 -122000.0 -0.89 -1.2476 -1.0 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 A24 compound treatment 248850.0 -129000.0 -0.87 208000.0 -143000.0 -1.04 -1.3491 -0.9961 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B01 compound treatment 252640.0 -125000.0 -0.84 289490.0 -61900.0 -0.45 -0.9138 -0.9562 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B02 compound treatment 173120.0 -204000.0 -1.38 207860.0 -144000.0 -1.04 -1.7116 -0.9902 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B03 compound treatment 268080.0 -109000.0 -0.74 278330.0 -73100.0 -0.53 -0.8972 -0.9865 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B04 compound treatment 239280.0 -138000.0 -0.93 222280.0 -129000.0 -0.93 -1.3217 -1.0 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B05 compound treatment 356560.0 -21000.0 -0.14 221210.0 -130000.0 -0.94 -0.7668 -0.8045 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B06 compound treatment 184170.0 -193000.0 -1.31 225220.0 -126000.0 -0.91 -1.57 -0.9847 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B07 compound treatment 211870.0 -166000.0 -1.12 290950.0 -60500.0 -0.44 -1.1012 -0.916 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B08 compound treatment 242200.0 -135000.0 -0.91 257130.0 -94300.0 -0.68 -1.1294 -0.9896 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B09 compound treatment 197810.0 -180000.0 -1.21 252550.0 -98900.0 -0.72 -1.3649 -0.9682 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B10 compound treatment 270880.0 -107000.0 -0.72 183690.0 -168000.0 -1.21 -1.3683 -0.969 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B11 compound treatment 153520.0 -224000.0 -1.51 122500.0 -229000.0 -1.66 -2.2422 -0.999 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B12 compound treatment 141850.0 -236000.0 -1.59 145080.0 -206000.0 -1.49 -2.1824 -0.9995 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B13 mock treatment 379530.0 1970.0 0.01 368160.0 16700.0 0.12 0.0951 0.7799 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B14 mock treatment 397280.0 19700.0 0.13 320610.0 -30800.0 -0.22 -0.0635 -0.2444 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B15 compound treatment 323800.0 -53800.0 -0.36 261960.0 -89500.0 -0.65 -0.7148 -0.9627 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B16 compound treatment 131280.0 -246000.0 -1.66 146450.0 -205000.0 -1.48 -2.2259 -0.9984 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B17 compound treatment 336850.0 -40700.0 -0.28 252960.0 -98500.0 -0.71 -0.6985 -0.9143 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B18 compound treatment 104280.0 -273000.0 -1.85 111870.0 -240000.0 -1.73 -2.5319 -0.9995 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B19 compound treatment 139680.0 -238000.0 -1.61 153830.0 -198000.0 -1.43 -2.1479 -0.9983 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B20 compound treatment 158330.0 -219000.0 -1.48 150400.0 -201000.0 -1.46 -2.0764 -1.0 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B21 compound treatment 252800.0 -125000.0 -0.84 240220.0 -111000.0 -0.8 -1.1653 -0.9997 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B22 compound treatment 144680.0 -233000.0 -1.57 133990.0 -217000.0 -1.57 -2.2256 -1.0 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B23 compound treatment 175360.0 -202000.0 -1.37 135080.0 -216000.0 -1.57 -2.0734 -0.9977 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 B24 compound treatment 239570.0 -138000.0 -0.93 259600.0 -91800.0 -0.66 -1.1293 -0.9862 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C01 compound treatment 261760.0 -116000.0 -0.78 289190.0 -62200.0 -0.45 -0.8718 -0.9656 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C02 compound treatment 186610.0 -191000.0 -1.29 179840.0 -172000.0 -1.24 -1.7906 -0.9998 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C03 compound treatment 216000.0 -162000.0 -1.09 266500.0 -84900.0 -0.61 -1.2066 -0.9631 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C04 compound treatment 365890.0 -11700.0 -0.08 295890.0 -55500.0 -0.4 -0.34 -0.83 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C05 compound treatment 315680.0 -61900.0 -0.42 182580.0 -169000.0 -1.22 -1.1599 -0.8979 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C06 compound treatment 232440.0 -145000.0 -0.98 232320.0 -119000.0 -0.86 -1.303 -0.9979 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C07 compound treatment 383520.0 5960.0 0.04 315940.0 -35500.0 -0.26 -0.1531 -0.5891 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C08 compound treatment 448560.0 71000.0 0.48 345540.0 -5880.0 -0.04 0.3091 0.6419 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C09 compound treatment 377080.0 -485.0 0.0 362740.0 11300.0 0.08 0.0557 0.6783 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C10 compound treatment 144120.0 -233000.0 -1.58 137940.0 -213000.0 -1.55 -2.2081 -0.9999 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C11 mock treatment 402690.0 25100.0 0.17 313970.0 -37400.0 -0.27 -0.0716 -0.2239 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C12 mock treatment 420980.0 43400.0 0.29 396580.0 45200.0 0.33 0.4386 0.9985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C13 compound treatment 400090.0 22500.0 0.15 396960.0 45500.0 0.33 0.3408 0.9384 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C14 compound treatment 281160.0 -96400.0 -0.65 247110.0 -104000.0 -0.76 -0.9945 -0.9973 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C15 mock treatment 365290.0 -12300.0 -0.08 370720.0 19300.0 0.14 0.0402 0.2472 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C16 mock treatment 420750.0 43200.0 0.29 334120.0 -17300.0 -0.13 0.1178 0.371 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C17 compound treatment 324970.0 -52600.0 -0.36 263520.0 -87900.0 -0.64 -0.7012 -0.9621 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C18 compound treatment 232800.0 -145000.0 -0.98 227640.0 -124000.0 -0.9 -1.3252 -0.999 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C19 compound treatment 377690.0 125.0 0.0 366650.0 15200.0 0.11 0.0786 0.7125 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C20 compound treatment 180960.0 -197000.0 -1.33 173440.0 -178000.0 -1.29 -1.8503 -0.9999 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C21 compound treatment 297830.0 -79700.0 -0.54 271490.0 -79900.0 -0.58 -0.7901 -0.9994 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C22 compound treatment 334290.0 -43300.0 -0.29 288960.0 -62500.0 -0.45 -0.5264 -0.9778 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C23 compound treatment 281490.0 -96100.0 -0.65 313030.0 -38400.0 -0.28 -0.6555 -0.9283 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 C24 compound treatment 309410.0 -68200.0 -0.46 371060.0 19600.0 0.14 -0.2251 -0.467 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D01 compound treatment 186400.0 -191000.0 -1.29 205120.0 -146000.0 -1.06 -1.6622 -0.9951 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D02 compound treatment 240590.0 -137000.0 -0.93 241200.0 -110000.0 -0.8 -1.2186 -0.9973 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D03 compound treatment 168040.0 -210000.0 -1.42 142090.0 -209000.0 -1.52 -2.0725 -0.9994 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D04 compound treatment 269050.0 -109000.0 -0.73 219730.0 -132000.0 -0.95 -1.1925 -0.9916 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D05 compound treatment 199360.0 -178000.0 -1.2 202150.0 -149000.0 -1.08 -1.6155 -0.9985 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D06 compound treatment 338780.0 -38800.0 -0.26 321970.0 -29400.0 -0.21 -0.336 -0.9947 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D07 compound treatment 257760.0 -120000.0 -0.81 204100.0 -147000.0 -1.07 -1.3265 -0.9908 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D08 compound treatment 285930.0 -91600.0 -0.62 309080.0 -42300.0 -0.31 -0.6545 -0.9474 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D09 compound treatment 340320.0 -37200.0 -0.25 253720.0 -97700.0 -0.71 -0.678 -0.9032 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D10 compound treatment 234130.0 -143000.0 -0.97 213860.0 -138000.0 -1.0 -1.3894 -0.9999 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D11 mock treatment 477240.0 99700.0 0.67 335100.0 -16300.0 -0.12 0.3927 0.5743 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D12 mock treatment 457970.0 80400.0 0.54 420480.0 69100.0 0.5 0.7377 0.9991 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D13 compound treatment 312810.0 -64800.0 -0.44 256760.0 -94700.0 -0.69 -0.7939 -0.9765 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D14 compound treatment 289520.0 -88000.0 -0.59 281920.0 -69500.0 -0.5 -0.7764 -0.9965 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D15 mock treatment 385080.0 7520.0 0.05 360430.0 9010.0 0.07 0.0821 0.9923 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D16 mock treatment 379260.0 1700.0 0.01 398500.0 47100.0 0.34 0.2491 0.7305 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D17 compound treatment 229090.0 -148000.0 -1.0 232640.0 -119000.0 -0.86 -1.3174 -0.9971 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D18 compound treatment 286320.0 -91200.0 -0.62 275040.0 -76400.0 -0.55 -0.8269 -0.9985 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D19 compound treatment 311540.0 -66000.0 -0.45 287490.0 -63900.0 -0.46 -0.6427 -0.9998 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D20 compound treatment 250580.0 -127000.0 -0.86 260880.0 -90500.0 -0.66 -1.0701 -0.9912 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D21 compound treatment 183290.0 -194000.0 -1.31 153120.0 -198000.0 -1.44 -1.9432 -0.999 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D22 compound treatment 281160.0 -96400.0 -0.65 222720.0 -129000.0 -0.93 -1.1194 -0.9847 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D23 compound treatment 271140.0 -106000.0 -0.72 238720.0 -113000.0 -0.82 -1.0853 -0.998 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 D24 compound treatment 48260.0 -329000.0 -2.23 42260.0 -309000.0 -2.24 -3.1558 -1.0 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E01 mock treatment 381490.0 3930.0 0.03 439600.0 88200.0 0.64 0.4701 0.7358 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E02 mock treatment 381930.0 4370.0 0.03 316590.0 -34800.0 -0.25 -0.1574 -0.6201 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E03 compound treatment 254980.0 -123000.0 -0.83 338240.0 -13200.0 -0.1 -0.6531 -0.7834 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E04 compound treatment 285770.0 -91800.0 -0.62 254900.0 -96500.0 -0.7 -0.9326 -0.9982 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E05 compound treatment 321610.0 -56000.0 -0.38 399740.0 48300.0 0.35 -0.02 -0.0388 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E06 compound treatment 271010.0 -107000.0 -0.72 242800.0 -109000.0 -0.79 -1.0651 -0.999 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E07 compound treatment 181170.0 -196000.0 -1.33 165670.0 -186000.0 -1.34 -1.8891 -1.0 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E08 compound treatment 435270.0 57700.0 0.39 282880.0 -68500.0 -0.5 -0.0751 -0.119 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E09 mock treatment 433380.0 55800.0 0.38 384130.0 32700.0 0.24 0.4341 0.9749 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E10 mock treatment 425550.0 48000.0 0.32 340320.0 -11100.0 -0.08 0.1725 0.5163 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E11 compound treatment 286560.0 -91000.0 -0.61 193920.0 -157000.0 -1.14 -1.241 -0.958 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E12 compound treatment 396860.0 19300.0 0.13 352750.0 1330.0 0.01 0.099 0.7574 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E13 compound treatment 336870.0 -40700.0 -0.27 332260.0 -19200.0 -0.14 -0.2925 -0.9498 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E14 compound treatment 386080.0 8520.0 0.06 259330.0 -92100.0 -0.67 -0.4307 -0.6437 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E15 compound treatment 339010.0 -38600.0 -0.26 344390.0 -7030.0 -0.05 -0.2202 -0.8295 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E16 compound treatment 372730.0 -4830.0 -0.03 283890.0 -67500.0 -0.49 -0.3687 -0.7527 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E17 mock treatment 398160.0 20600.0 0.14 289760.0 -61700.0 -0.45 -0.2172 -0.4646 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E18 mock treatment 358490.0 -19100.0 -0.13 371640.0 20200.0 0.15 0.0124 0.0635 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E19 compound treatment 352100.0 -25500.0 -0.17 300130.0 -51300.0 -0.37 -0.3842 -0.9389 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E20 compound treatment 228650.0 -149000.0 -1.01 185340.0 -166000.0 -1.2 -1.5616 -0.9961 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E21 compound treatment 182880.0 -195000.0 -1.32 155220.0 -196000.0 -1.42 -1.9344 -0.9993 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E22 compound treatment 225120.0 -152000.0 -1.03 237340.0 -114000.0 -0.83 -1.3123 -0.994 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E23 compound treatment 256850.0 -121000.0 -0.82 204800.0 -147000.0 -1.06 -1.3272 -0.9915 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 E24 compound treatment 143250.0 -234000.0 -1.58 138240.0 -213000.0 -1.54 -2.2107 -0.9999 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F01 mock treatment 410300.0 32700.0 0.22 186050.0 -165000.0 -1.2 -0.6901 -0.5669 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F02 mock treatment 440270.0 62700.0 0.42 301990.0 -49400.0 -0.36 0.0466 0.084 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F03 compound treatment 226030.0 -152000.0 -1.02 170400.0 -181000.0 -1.31 -1.6506 -0.9926 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F04 compound treatment 215050.0 -163000.0 -1.1 247240.0 -104000.0 -0.75 -1.3097 -0.9832 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F05 compound treatment 345770.0 -31800.0 -0.21 293510.0 -57900.0 -0.42 -0.4483 -0.9518 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F06 compound treatment 250430.0 -127000.0 -0.86 219690.0 -132000.0 -0.95 -1.2817 -0.9986 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F07 compound treatment 140020.0 -238000.0 -1.61 156890.0 -195000.0 -1.41 -2.1307 -0.9979 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F08 compound treatment 259730.0 -118000.0 -0.8 217970.0 -133000.0 -0.97 -1.2461 -0.9954 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F09 mock treatment 420160.0 42600.0 0.29 368170.0 16800.0 0.12 0.2893 0.9262 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F10 mock treatment 468990.0 91400.0 0.62 403300.0 51900.0 0.38 0.7024 0.9715 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F11 compound treatment 260060.0 -118000.0 -0.79 275110.0 -76300.0 -0.55 -0.952 -0.9843 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F12 compound treatment 248010.0 -130000.0 -0.88 262290.0 -89100.0 -0.65 -1.0752 -0.9887 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F13 compound treatment 315730.0 -61800.0 -0.42 253550.0 -97900.0 -0.71 -0.7964 -0.9683 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F14 compound treatment 155720.0 -222000.0 -1.5 109770.0 -242000.0 -1.75 -2.2968 -0.997 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F15 compound treatment 150480.0 -227000.0 -1.53 227730.0 -124000.0 -0.9 -1.7181 -0.9671 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F16 compound treatment 184540.0 -193000.0 -1.3 148340.0 -203000.0 -1.47 -1.9617 -0.9982 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F17 mock treatment 408260.0 30700.0 0.21 206040.0 -145000.0 -1.05 -0.5975 -0.557 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F18 mock treatment 332960.0 -44600.0 -0.3 318100.0 -33300.0 -0.24 -0.3836 -0.9939 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F19 compound treatment 232270.0 -145000.0 -0.98 191040.0 -160000.0 -1.16 -1.5151 -0.9965 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F20 compound treatment 156100.0 -221000.0 -1.5 122020.0 -229000.0 -1.66 -2.2323 -0.9987 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F21 compound treatment 237930.0 -140000.0 -0.94 259610.0 -91800.0 -0.66 -1.1371 -0.9853 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F22 compound treatment 173160.0 -204000.0 -1.38 168420.0 -183000.0 -1.32 -1.9133 -0.9998 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F23 compound treatment 270880.0 -107000.0 -0.72 161920.0 -189000.0 -1.37 -1.4797 -0.9549 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 F24 compound treatment 140010.0 -238000.0 -1.61 122910.0 -229000.0 -1.65 -2.3046 -0.9999 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G01 compound treatment 248580.0 -129000.0 -0.87 366240.0 14800.0 0.11 -0.5404 -0.6154 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G02 compound treatment 450880.0 73300.0 0.5 333920.0 -17500.0 -0.13 0.2607 0.5099 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G03 mock treatment 480410.0 103000.0 0.69 373670.0 22300.0 0.16 0.6053 0.8485 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G04 mock treatment 304180.0 -73400.0 -0.5 209990.0 -141000.0 -1.02 -1.0745 -0.9446 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G05 compound treatment 311040.0 -66500.0 -0.45 483170.0 132000.0 0.95 0.3566 0.3382 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G06 compound treatment 288010.0 -89600.0 -0.61 382610.0 31200.0 0.23 -0.2682 -0.4153 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G07 compound treatment 250530.0 -127000.0 -0.86 381240.0 29800.0 0.22 -0.4543 -0.5133 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G08 compound treatment 433680.0 56100.0 0.38 368020.0 16600.0 0.12 0.3531 0.8877 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G09 compound treatment 323360.0 -54200.0 -0.37 324000.0 -27400.0 -0.2 -0.3993 -0.9586 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G10 compound treatment 287430.0 -90100.0 -0.61 327200.0 -24200.0 -0.18 -0.5546 -0.8751 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G11 compound treatment 367490.0 -10100.0 -0.07 344390.0 -7030.0 -0.05 -0.0841 -0.9897 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G12 compound treatment 284820.0 -92700.0 -0.63 312710.0 -38700.0 -0.28 -0.6412 -0.9341 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G13 compound treatment 500190.0 123000.0 0.83 426240.0 74800.0 0.54 0.9689 0.9788 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G14 compound treatment 361320.0 -16200.0 -0.11 236510.0 -115000.0 -0.83 -0.6658 -0.7935 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G15 compound treatment 367280.0 -10300.0 -0.07 288200.0 -63200.0 -0.46 -0.3727 -0.8053 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G16 compound treatment 288370.0 -89200.0 -0.6 264920.0 -86500.0 -0.63 -0.8689 -0.9998 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G17 compound treatment 378320.0 755.0 0.01 324400.0 -27000.0 -0.2 -0.1347 -0.6884 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G18 compound treatment 300370.0 -77200.0 -0.52 313600.0 -37800.0 -0.27 -0.5624 -0.9547 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G19 mock treatment 363420.0 -14100.0 -0.1 426200.0 74800.0 0.54 0.3152 0.5734 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G20 mock treatment 285250.0 -92300.0 -0.62 331290.0 -20100.0 -0.15 -0.5441 -0.8494 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G21 compound treatment 358920.0 -18600.0 -0.13 357570.0 6150.0 0.04 -0.0576 -0.4309 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G22 compound treatment 348810.0 -28800.0 -0.19 361760.0 10300.0 0.07 -0.0844 -0.4055 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G23 compound treatment 249290.0 -128000.0 -0.87 330150.0 -21300.0 -0.15 -0.7217 -0.8199 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 G24 compound treatment 265680.0 -112000.0 -0.76 337920.0 -13500.0 -0.1 -0.6036 -0.7919 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H01 compound treatment 195150.0 -182000.0 -1.23 187330.0 -164000.0 -1.19 -1.7114 -0.9998 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H02 compound treatment 202430.0 -175000.0 -1.18 189840.0 -162000.0 -1.17 -1.6638 -1.0 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H03 mock treatment 427540.0 50000.0 0.34 235220.0 -116000.0 -0.84 -0.356 -0.3928 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H04 mock treatment 403750.0 26200.0 0.18 359300.0 7880.0 0.06 0.1655 0.8901 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H05 compound treatment 263550.0 -114000.0 -0.77 223570.0 -128000.0 -0.93 -1.1991 -0.9958 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H06 compound treatment 250880.0 -127000.0 -0.86 178720.0 -173000.0 -1.25 -1.4892 -0.9829 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H07 compound treatment 291090.0 -86500.0 -0.58 278640.0 -72800.0 -0.53 -0.7857 -0.9987 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H08 compound treatment 194160.0 -183000.0 -1.24 210240.0 -141000.0 -1.02 -1.5989 -0.9954 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H09 compound treatment 288740.0 -88800.0 -0.6 329680.0 -21700.0 -0.16 -0.5356 -0.8633 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H10 compound treatment 354110.0 -23500.0 -0.16 360080.0 8660.0 0.06 -0.0677 -0.3973 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H11 compound treatment 317560.0 -60000.0 -0.41 170250.0 -181000.0 -1.31 -1.214 -0.8844 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H12 compound treatment 224600.0 -153000.0 -1.03 212570.0 -139000.0 -1.01 -1.4415 -0.9999 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H13 compound treatment 296650.0 -80900.0 -0.55 291470.0 -59900.0 -0.43 -0.6934 -0.9935 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H14 compound treatment 313990.0 -63600.0 -0.43 244450.0 -107000.0 -0.77 -0.8513 -0.9614 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H15 compound treatment 282240.0 -95300.0 -0.64 187360.0 -164000.0 -1.19 -1.2952 -0.9587 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H16 compound treatment 226640.0 -151000.0 -1.02 207910.0 -144000.0 -1.04 -1.4556 -1.0 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H17 compound treatment 353040.0 -24500.0 -0.17 388420.0 37000.0 0.27 0.0722 0.2293 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H18 compound treatment 237880.0 -140000.0 -0.94 167520.0 -184000.0 -1.33 -1.6087 -0.9858 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H19 mock treatment 331360.0 -46200.0 -0.31 329840.0 -21600.0 -0.16 -0.3312 -0.9487 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H20 mock treatment 483880.0 106000.0 0.72 415380.0 64000.0 0.46 0.8354 0.9774 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H21 compound treatment 298140.0 -79400.0 -0.54 236410.0 -115000.0 -0.83 -0.9682 -0.9774 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H22 compound treatment 179480.0 -198000.0 -1.34 147770.0 -204000.0 -1.47 -1.9888 -0.9988 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H23 compound treatment 216600.0 -161000.0 -1.09 174080.0 -177000.0 -1.28 -1.6768 -0.9966 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 H24 compound treatment 229780.0 -148000.0 -1.0 159200.0 -192000.0 -1.39 -1.69 -0.9868 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I01 compound treatment 299640.0 -77900.0 -0.53 186080.0 -165000.0 -1.2 -1.2186 -0.932 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I02 compound treatment 334640.0 -42900.0 -0.29 260330.0 -91100.0 -0.66 -0.6713 -0.932 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I03 compound treatment 320980.0 -56600.0 -0.38 314590.0 -36800.0 -0.27 -0.4588 -0.9845 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I04 compound treatment 167570.0 -210000.0 -1.42 268400.0 -83000.0 -0.6 -1.4282 -0.9269 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I05 mock treatment 352410.0 -25200.0 -0.17 325690.0 -25700.0 -0.19 -0.2519 -0.999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I06 mock treatment 392380.0 14800.0 0.1 407610.0 56200.0 0.41 0.3584 0.8556 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I07 compound treatment 330620.0 -46900.0 -0.32 408160.0 56700.0 0.41 0.0662 0.1275 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I08 compound treatment 458770.0 81200.0 0.55 404170.0 52800.0 0.38 0.658 0.9843 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I09 compound treatment 309220.0 -68300.0 -0.46 348640.0 -2780.0 -0.02 -0.3407 -0.7372 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I10 compound treatment 337990.0 -39600.0 -0.27 327720.0 -23700.0 -0.17 -0.3104 -0.977 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I11 compound treatment 416380.0 38800.0 0.26 319770.0 -31600.0 -0.23 0.0235 0.0674 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I12 compound treatment 233490.0 -144000.0 -0.97 275090.0 -76300.0 -0.55 -1.079 -0.964 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I13 compound treatment 370040.0 -7520.0 -0.05 303360.0 -48100.0 -0.35 -0.2819 -0.8019 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I14 compound treatment 367440.0 -10100.0 -0.07 309890.0 -41500.0 -0.3 -0.2609 -0.8464 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I15 compound treatment 432120.0 54600.0 0.37 221050.0 -130000.0 -0.94 -0.4066 -0.4014 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I16 compound treatment 285760.0 -91800.0 -0.62 257480.0 -93900.0 -0.68 -0.9195 -0.9989 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I17 compound treatment 274300.0 -103000.0 -0.7 195720.0 -156000.0 -1.13 -1.2903 -0.9734 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I18 compound treatment 275200.0 -102000.0 -0.69 203010.0 -148000.0 -1.07 -1.2487 -0.9773 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I19 compound treatment 334210.0 -43400.0 -0.29 400490.0 49100.0 0.36 0.0441 0.0957 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I20 compound treatment 242400.0 -135000.0 -0.91 273970.0 -77400.0 -0.56 -1.0422 -0.9725 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I21 mock treatment 336000.0 -41600.0 -0.28 265060.0 -86400.0 -0.63 -0.6406 -0.9348 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I22 mock treatment 366810.0 -10800.0 -0.07 447210.0 95800.0 0.69 0.439 0.6296 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I23 compound treatment 354320.0 -23200.0 -0.16 294020.0 -57400.0 -0.42 -0.4048 -0.9115 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 I24 compound treatment 282290.0 -95300.0 -0.64 226100.0 -125000.0 -0.91 -1.0967 -0.9859 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J01 compound treatment 185190.0 -192000.0 -1.3 189990.0 -161000.0 -1.17 -1.7454 -0.9986 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J02 compound treatment 152760.0 -225000.0 -1.52 155690.0 -196000.0 -1.42 -2.0759 -0.9994 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J03 compound treatment 204640.0 -173000.0 -1.17 163430.0 -188000.0 -1.36 -1.7884 -0.9971 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J04 compound treatment 183760.0 -194000.0 -1.31 124510.0 -227000.0 -1.64 -2.0874 -0.9937 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J05 mock treatment 318610.0 -59000.0 -0.4 398140.0 46700.0 0.34 -0.0425 -0.0813 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J06 mock treatment 319470.0 -58100.0 -0.39 255130.0 -96300.0 -0.7 -0.7704 -0.9631 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J07 compound treatment 230990.0 -147000.0 -0.99 243860.0 -108000.0 -0.78 -1.2508 -0.9929 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J08 compound treatment 271860.0 -106000.0 -0.71 237410.0 -114000.0 -0.83 -1.0886 -0.9974 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J09 compound treatment 297030.0 -80500.0 -0.54 215120.0 -136000.0 -0.99 -1.0824 -0.9607 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J10 compound treatment 237820.0 -140000.0 -0.94 267040.0 -84400.0 -0.61 -1.0996 -0.9778 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J11 compound treatment 484270.0 107000.0 0.72 250850.0 -101000.0 -0.73 -0.0049 -0.0048 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J12 compound treatment 264910.0 -113000.0 -0.76 221700.0 -130000.0 -0.94 -1.2022 -0.9946 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J13 compound treatment 174560.0 -203000.0 -1.37 174560.0 -177000.0 -1.28 -1.8752 -0.9994 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J14 compound treatment 219920.0 -158000.0 -1.07 171550.0 -180000.0 -1.3 -1.6739 -0.995 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J15 compound treatment 274970.0 -103000.0 -0.69 221340.0 -130000.0 -0.94 -1.156 -0.9887 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J16 compound treatment 306620.0 -70900.0 -0.48 280000.0 -71400.0 -0.52 -0.7045 -0.9993 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J17 compound treatment 219360.0 -158000.0 -1.07 215540.0 -136000.0 -0.98 -1.4514 -0.9991 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J18 compound treatment 259520.0 -118000.0 -0.8 153880.0 -198000.0 -1.43 -1.5751 -0.962 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J19 compound treatment 222370.0 -155000.0 -1.05 206260.0 -145000.0 -1.05 -1.4845 -1.0 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J20 compound treatment 260000.0 -118000.0 -0.79 244240.0 -107000.0 -0.78 -1.1103 -0.9999 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J21 mock treatment 242150.0 -135000.0 -0.91 257790.0 -93600.0 -0.68 -1.1262 -0.9891 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J22 mock treatment 282520.0 -95000.0 -0.64 241690.0 -110000.0 -0.79 -1.0158 -0.9944 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J23 compound treatment 225960.0 -152000.0 -1.02 290830.0 -60600.0 -0.44 -1.0345 -0.9283 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 J24 compound treatment 158800.0 -219000.0 -1.48 172240.0 -179000.0 -1.3 -1.9624 -0.9979 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K01 compound treatment 251200.0 -126000.0 -0.85 231840.0 -120000.0 -0.87 -1.2158 -1.0 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K02 compound treatment 262880.0 -115000.0 -0.77 363520.0 12100.0 0.09 -0.486 -0.6232 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K03 compound treatment 325440.0 -52100.0 -0.35 397090.0 45700.0 0.33 -0.0152 -0.0316 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K04 compound treatment 441170.0 63600.0 0.43 279460.0 -72000.0 -0.52 -0.0644 -0.0954 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K05 compound treatment 202560.0 -175000.0 -1.18 273120.0 -78300.0 -0.57 -1.2369 -0.9433 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K06 compound treatment 244960.0 -133000.0 -0.9 258990.0 -92400.0 -0.67 -1.1067 -0.9897 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K07 mock treatment 348570.0 -29000.0 -0.2 477440.0 126000.0 0.91 0.5066 0.5429 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K08 mock treatment 278250.0 -99300.0 -0.67 457640.0 106000.0 0.77 0.0692 0.0678 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K09 compound treatment 318940.0 -58600.0 -0.4 363310.0 11900.0 0.09 -0.2192 -0.5408 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K10 compound treatment 511040.0 133000.0 0.9 437600.0 86200.0 0.62 1.0789 0.9838 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K11 compound treatment 468750.0 91200.0 0.62 256480.0 -94900.0 -0.69 -0.0503 -0.0545 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K12 compound treatment 395840.0 18300.0 0.12 290140.0 -61300.0 -0.44 -0.2263 -0.4916 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K13 compound treatment 353830.0 -23700.0 -0.16 263450.0 -88000.0 -0.64 -0.5637 -0.8584 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K14 compound treatment 282930.0 -94600.0 -0.64 231090.0 -120000.0 -0.87 -1.0681 -0.9884 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K15 mock treatment 359450.0 -18100.0 -0.12 385330.0 33900.0 0.25 0.0871 0.3173 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K16 mock treatment 343460.0 -34100.0 -0.23 382250.0 30800.0 0.22 -0.0051 -0.0159 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K17 compound treatment 245300.0 -132000.0 -0.89 196930.0 -154000.0 -1.12 -1.4227 -0.9938 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K18 compound treatment 252340.0 -125000.0 -0.85 166140.0 -185000.0 -1.34 -1.5467 -0.9753 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K19 compound treatment 261190.0 -116000.0 -0.79 303610.0 -47800.0 -0.35 -0.8007 -0.932 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K20 compound treatment 305660.0 -71900.0 -0.49 206600.0 -145000.0 -1.05 -1.0848 -0.9389 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K21 compound treatment 273210.0 -104000.0 -0.71 214490.0 -137000.0 -0.99 -1.1995 -0.9861 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K22 compound treatment 359040.0 -18500.0 -0.13 243940.0 -107000.0 -0.78 -0.6386 -0.8104 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K23 mock treatment 337350.0 -40200.0 -0.27 454080.0 103000.0 0.74 0.3334 0.4213 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 K24 mock treatment 419530.0 42000.0 0.28 396070.0 44700.0 0.32 0.4291 0.9979 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L01 compound treatment 307700.0 -69900.0 -0.47 324870.0 -26500.0 -0.19 -0.4697 -0.9215 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L02 compound treatment 150770.0 -227000.0 -1.53 298780.0 -52600.0 -0.38 -1.353 -0.8568 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L03 compound treatment 167090.0 -210000.0 -1.42 255730.0 -95700.0 -0.69 -1.4954 -0.9453 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L04 compound treatment 164050.0 -214000.0 -1.44 176130.0 -175000.0 -1.27 -1.9174 -0.998 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L05 compound treatment 302200.0 -75400.0 -0.51 354470.0 3050.0 0.02 -0.3444 -0.6758 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L06 compound treatment 321620.0 -55900.0 -0.38 351000.0 -415.0 0.0 -0.2694 -0.7127 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L07 mock treatment 334720.0 -42800.0 -0.29 205720.0 -146000.0 -1.05 -0.9505 -0.8691 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L08 mock treatment 439380.0 61800.0 0.42 375240.0 23800.0 0.17 0.4173 0.9235 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L09 compound treatment 223420.0 -154000.0 -1.04 365760.0 14300.0 0.1 -0.663 -0.6335 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L10 compound treatment 268760.0 -109000.0 -0.74 263400.0 -88000.0 -0.64 -0.9704 -0.9975 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L11 compound treatment 236670.0 -141000.0 -0.95 438370.0 87000.0 0.63 -0.2281 -0.1998 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L12 compound treatment 247720.0 -130000.0 -0.88 310940.0 -40500.0 -0.29 -0.8276 -0.8947 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L13 compound treatment 431950.0 54400.0 0.37 291840.0 -59600.0 -0.43 -0.0451 -0.0796 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L14 compound treatment 266840.0 -111000.0 -0.75 210500.0 -141000.0 -1.02 -1.2503 -0.9884 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L15 mock treatment 473610.0 96000.0 0.65 401560.0 50100.0 0.36 0.7156 0.9623 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L16 mock treatment 375840.0 -1720.0 -0.01 466360.0 115000.0 0.83 0.5801 0.6971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L17 compound treatment 198980.0 -179000.0 -1.21 187600.0 -164000.0 -1.19 -1.6918 -1.0 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L18 compound treatment 259480.0 -118000.0 -0.8 300320.0 -51100.0 -0.37 -0.8257 -0.9389 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L19 compound treatment 463680.0 86100.0 0.58 413120.0 61700.0 0.45 0.7273 0.9915 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L20 compound treatment 266030.0 -112000.0 -0.75 287170.0 -64200.0 -0.47 -0.8617 -0.9731 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L21 compound treatment 362080.0 -15500.0 -0.1 375450.0 24000.0 0.17 0.049 0.2416 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L22 compound treatment 272770.0 -105000.0 -0.71 341980.0 -9440.0 -0.07 -0.549 -0.7717 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L23 mock treatment 308930.0 -68600.0 -0.46 385470.0 34100.0 0.25 -0.1536 -0.2925 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 L24 mock treatment 372810.0 -4750.0 -0.03 479720.0 128000.0 0.93 0.634 0.6822 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M01 compound treatment 139720.0 -238000.0 -1.61 240930.0 -110000.0 -0.8 -1.7019 -0.9481 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M02 compound treatment 276430.0 -101000.0 -0.68 298210.0 -53200.0 -0.39 -0.7555 -0.9632 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M03 compound treatment 229860.0 -148000.0 -1.0 130740.0 -221000.0 -1.6 -1.8353 -0.9744 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M04 compound treatment 325980.0 -51600.0 -0.35 417440.0 66000.0 0.48 0.0915 0.1547 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M05 compound treatment 224240.0 -153000.0 -1.04 282240.0 -69200.0 -0.5 -1.0866 -0.9444 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M06 compound treatment 458670.0 81100.0 0.55 359710.0 8290.0 0.06 0.43 0.7799 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M07 compound treatment 227390.0 -150000.0 -1.01 215050.0 -136000.0 -0.99 -1.4155 -0.9999 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M08 compound treatment 208960.0 -169000.0 -1.14 218430.0 -133000.0 -0.96 -1.4863 -0.9965 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M09 mock treatment 462490.0 84900.0 0.57 461820.0 110000.0 0.8 0.9709 0.9868 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M10 mock treatment 528490.0 151000.0 1.02 402260.0 50800.0 0.37 0.9813 0.9052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M11 compound treatment 344210.0 -33400.0 -0.23 272980.0 -78400.0 -0.57 -0.5608 -0.9181 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M12 compound treatment 532320.0 155000.0 1.05 424850.0 73400.0 0.53 1.1153 0.9508 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M13 mock treatment 483700.0 106000.0 0.72 380750.0 29300.0 0.21 0.6572 0.8788 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M14 mock treatment 296900.0 -80700.0 -0.55 242410.0 -109000.0 -0.79 -0.9434 -0.9837 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M15 compound treatment 331080.0 -46500.0 -0.31 293810.0 -57600.0 -0.42 -0.517 -0.9902 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M16 compound treatment 151040.0 -227000.0 -1.53 197920.0 -153000.0 -1.11 -1.868 -0.9876 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M17 compound treatment 233470.0 -144000.0 -0.97 341790.0 -9630.0 -0.07 -0.7377 -0.7558 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M18 compound treatment 294460.0 -83100.0 -0.56 348690.0 -2730.0 -0.02 -0.411 -0.7315 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M19 compound treatment 197130.0 -180000.0 -1.22 328900.0 -22500.0 -0.16 -0.9773 -0.7946 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M20 compound treatment 256770.0 -121000.0 -0.82 417050.0 65600.0 0.48 -0.2412 -0.2554 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M21 compound treatment 273130.0 -104000.0 -0.71 328160.0 -23300.0 -0.17 -0.618 -0.8519 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M22 compound treatment 351860.0 -25700.0 -0.17 233330.0 -118000.0 -0.85 -0.7273 -0.8337 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M23 compound treatment 187650.0 -190000.0 -1.28 326890.0 -24500.0 -0.18 -1.0329 -0.7973 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 M24 compound treatment 337500.0 -40100.0 -0.27 316370.0 -35000.0 -0.25 -0.3708 -0.9995 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N01 compound treatment 325400.0 -52200.0 -0.35 457050.0 106000.0 0.76 0.2915 0.3462 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N02 compound treatment 291460.0 -86100.0 -0.58 383690.0 32300.0 0.23 -0.2462 -0.3927 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N03 compound treatment 298400.0 -79200.0 -0.53 175370.0 -176000.0 -1.27 -1.2794 -0.9257 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N04 compound treatment 425920.0 48400.0 0.33 301860.0 -49600.0 -0.36 -0.0226 -0.0466 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N05 compound treatment 365690.0 -11900.0 -0.08 356430.0 5010.0 0.04 -0.0311 -0.3528 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N06 compound treatment 488480.0 111000.0 0.75 327450.0 -24000.0 -0.17 0.4073 0.5294 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N07 compound treatment 380720.0 3160.0 0.02 269920.0 -81500.0 -0.59 -0.4021 -0.6811 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N08 compound treatment 257920.0 -120000.0 -0.81 249770.0 -102000.0 -0.74 -1.0919 -0.9989 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N09 mock treatment 468370.0 90800.0 0.61 466400.0 115000.0 0.83 1.0224 0.9887 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N10 mock treatment 491260.0 114000.0 0.77 268250.0 -83200.0 -0.6 0.1175 0.1204 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N11 compound treatment 416440.0 38900.0 0.26 326730.0 -24700.0 -0.18 0.0594 0.1869 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N12 compound treatment 362560.0 -15000.0 -0.1 375940.0 24500.0 0.18 0.0538 0.2634 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N13 mock treatment 365890.0 -11700.0 -0.08 407360.0 55900.0 0.4 0.2306 0.5589 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N14 mock treatment 394720.0 17200.0 0.12 411290.0 59900.0 0.43 0.3884 0.8658 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N15 compound treatment 503400.0 126000.0 0.85 395760.0 44300.0 0.32 0.8282 0.9113 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N16 compound treatment 303130.0 -74400.0 -0.5 298800.0 -52600.0 -0.38 -0.625 -0.9906 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N17 compound treatment 414890.0 37300.0 0.25 390660.0 39200.0 0.28 0.3792 0.9982 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N18 compound treatment 225520.0 -152000.0 -1.03 272390.0 -79000.0 -0.57 -1.1309 -0.9618 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N19 compound treatment 297530.0 -80000.0 -0.54 348080.0 -3340.0 -0.02 -0.3995 -0.7379 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N20 compound treatment 217680.0 -160000.0 -1.08 210420.0 -141000.0 -1.02 -1.4856 -0.9996 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N21 compound treatment 281600.0 -96000.0 -0.65 315100.0 -36300.0 -0.26 -0.6444 -0.921 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N22 compound treatment 165760.0 -212000.0 -1.43 179230.0 -172000.0 -1.25 -1.8933 -0.9976 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N23 compound treatment 223040.0 -155000.0 -1.04 264320.0 -87100.0 -0.63 -1.1841 -0.9708 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 N24 compound treatment 317140.0 -60400.0 -0.41 406990.0 55600.0 0.4 -0.0042 -0.0074 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O01 compound treatment 62720.0 -315000.0 -2.13 117310.0 -234000.0 -1.69 -2.7026 -0.9937 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O02 compound treatment 188810.0 -189000.0 -1.28 211320.0 -140000.0 -1.01 -1.6189 -0.9936 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O03 compound treatment 356210.0 -21400.0 -0.14 395620.0 44200.0 0.32 0.1242 0.3539 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O04 compound treatment 388130.0 10600.0 0.07 217280.0 -134000.0 -0.97 -0.6361 -0.6534 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O05 compound treatment 136870.0 -241000.0 -1.63 157330.0 -194000.0 -1.4 -2.1435 -0.9973 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O06 compound treatment 146880.0 -231000.0 -1.56 182490.0 -169000.0 -1.22 -1.9668 -0.9928 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O07 compound treatment 218270.0 -159000.0 -1.08 263070.0 -88300.0 -0.64 -1.2133 -0.9691 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O08 compound treatment 312530.0 -65000.0 -0.44 319790.0 -31600.0 -0.23 -0.4726 -0.9538 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O09 compound treatment 259770.0 -118000.0 -0.8 187150.0 -164000.0 -1.19 -1.4036 -0.9809 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O10 compound treatment 226720.0 -151000.0 -1.02 234420.0 -117000.0 -0.85 -1.3196 -0.9958 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O11 mock treatment 316990.0 -60600.0 -0.41 282140.0 -69300.0 -0.5 -0.644 -0.9949 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O12 mock treatment 195070.0 -182000.0 -1.23 171890.0 -180000.0 -1.3 -1.7909 -0.9997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O13 compound treatment 283010.0 -94600.0 -0.64 224440.0 -127000.0 -0.92 -1.1017 -0.9842 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O14 compound treatment 289470.0 -88100.0 -0.6 187150.0 -164000.0 -1.19 -1.2617 -0.9488 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O15 compound treatment 298300.0 -79300.0 -0.54 199520.0 -152000.0 -1.1 -1.1562 -0.9453 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O16 compound treatment 223410.0 -154000.0 -1.04 148130.0 -203000.0 -1.47 -1.7771 -0.9857 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O17 compound treatment 202820.0 -175000.0 -1.18 206780.0 -145000.0 -1.05 -1.5752 -0.9982 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O18 compound treatment 178010.0 -200000.0 -1.35 212700.0 -139000.0 -1.0 -1.6635 -0.9895 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O19 compound treatment 195220.0 -182000.0 -1.23 193480.0 -158000.0 -1.14 -1.6796 -0.9993 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O20 compound treatment 237380.0 -140000.0 -0.95 219880.0 -132000.0 -0.95 -1.3431 -1.0 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O21 compound treatment 231270.0 -146000.0 -0.99 186330.0 -165000.0 -1.2 -1.544 -0.9956 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O22 compound treatment 85980.0 -292000.0 -1.97 84380.0 -267000.0 -1.93 -2.76 -1.0 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O23 compound treatment 154890.0 -223000.0 -1.5 104070.0 -247000.0 -1.79 -2.33 -0.9963 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 O24 compound treatment 130250.0 -247000.0 -1.67 115140.0 -236000.0 -1.71 -2.391 -0.9999 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P01 compound treatment 145880.0 -232000.0 -1.57 221280.0 -130000.0 -0.94 -1.7731 -0.9705 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P02 compound treatment 182470.0 -195000.0 -1.32 217020.0 -134000.0 -0.97 -1.6201 -0.9888 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P03 compound treatment 252080.0 -125000.0 -0.85 204050.0 -147000.0 -1.07 -1.3539 -0.9935 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P04 compound treatment 205410.0 -172000.0 -1.16 220100.0 -131000.0 -0.95 -1.4947 -0.995 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P05 compound treatment 183270.0 -194000.0 -1.31 257960.0 -93500.0 -0.68 -1.4067 -0.9525 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P06 compound treatment 196180.0 -181000.0 -1.23 206260.0 -145000.0 -1.05 -1.6096 -0.9971 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P07 compound treatment 222240.0 -155000.0 -1.05 191120.0 -160000.0 -1.16 -1.5626 -0.9987 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P08 compound treatment 157170.0 -220000.0 -1.49 146130.0 -205000.0 -1.49 -2.1038 -1.0 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P09 compound treatment 251790.0 -126000.0 -0.85 243360.0 -108000.0 -0.78 -1.154 -0.9991 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P10 compound treatment 222350.0 -155000.0 -1.05 242510.0 -109000.0 -0.79 -1.299 -0.9901 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P11 mock treatment 190910.0 -187000.0 -1.26 170760.0 -181000.0 -1.31 -1.8165 -0.9998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P12 mock treatment 223290.0 -154000.0 -1.04 210570.0 -141000.0 -1.02 -1.458 -0.9999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P13 compound treatment 195650.0 -182000.0 -1.23 215880.0 -136000.0 -0.98 -1.5629 -0.9938 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P14 compound treatment 265120.0 -112000.0 -0.76 260750.0 -90700.0 -0.66 -1.0013 -0.9973 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P15 compound treatment 294450.0 -83100.0 -0.56 241940.0 -109000.0 -0.79 -0.9575 -0.9858 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P16 compound treatment 172350.0 -205000.0 -1.39 185340.0 -166000.0 -1.2 -1.8306 -0.9975 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P17 compound treatment 207160.0 -170000.0 -1.15 137510.0 -214000.0 -1.55 -1.9091 -0.9894 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P18 compound treatment 244180.0 -133000.0 -0.9 192960.0 -158000.0 -1.15 -1.4484 -0.9929 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P19 compound treatment 208000.0 -170000.0 -1.15 209730.0 -142000.0 -1.03 -1.5354 -0.9985 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P20 compound treatment 195730.0 -182000.0 -1.23 181770.0 -170000.0 -1.23 -1.7371 -1.0 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P21 compound treatment 180320.0 -197000.0 -1.33 246050.0 -105000.0 -0.76 -1.4817 -0.9649 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P22 compound treatment 182180.0 -195000.0 -1.32 201810.0 -150000.0 -1.08 -1.6993 -0.9952 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P23 compound treatment 194800.0 -183000.0 -1.23 144500.0 -207000.0 -1.5 -1.9324 -0.9954 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2094 P24 compound treatment 216800.0 -161000.0 -1.09 219220.0 -132000.0 -0.96 -1.4448 -0.998 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A01 compound treatment 310250.0 -43900.0 -0.3 210240.0 -107000.0 -0.77 -0.7569 -0.9135 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A02 compound treatment 275950.0 -78200.0 -0.53 289450.0 -27700.0 -0.2 -0.5153 -0.9117 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A03 compound treatment 291200.0 -63000.0 -0.43 183880.0 -133000.0 -0.96 -0.9828 -0.9324 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A04 compound treatment 222880.0 -131000.0 -0.89 174740.0 -142000.0 -1.03 -1.356 -0.9972 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A05 compound treatment 320170.0 -34000.0 -0.23 230500.0 -86600.0 -0.63 -0.6058 -0.9072 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A06 compound treatment 350470.0 -3700.0 -0.03 328450.0 11300.0 0.08 0.0404 0.4704 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A07 compound treatment 272060.0 -82100.0 -0.55 255000.0 -62100.0 -0.45 -0.7102 -0.9946 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A08 compound treatment 192680.0 -161000.0 -1.09 190750.0 -126000.0 -0.91 -1.4184 -0.9962 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A09 compound treatment 308130.0 -46000.0 -0.31 258080.0 -59000.0 -0.43 -0.5221 -0.9878 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A10 compound treatment 386600.0 32400.0 0.22 216330.0 -101000.0 -0.73 -0.3609 -0.4738 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A11 compound treatment 200810.0 -153000.0 -1.04 196330.0 -121000.0 -0.87 -1.351 -0.9964 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A12 compound treatment 259230.0 -94900.0 -0.64 220350.0 -96800.0 -0.7 -0.9489 -0.999 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A13 mock treatment 253560.0 -101000.0 -0.68 219460.0 -97600.0 -0.71 -0.9805 -0.9998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A14 mock treatment 314930.0 -39200.0 -0.27 348800.0 31700.0 0.23 -0.0253 -0.0721 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A15 compound treatment 355040.0 870.0 0.01 352770.0 35700.0 0.26 0.1867 0.723 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A16 compound treatment 297920.0 -56300.0 -0.38 261920.0 -55200.0 -0.4 -0.5512 -0.9997 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A17 compound treatment 309610.0 -44600.0 -0.3 300220.0 -16900.0 -0.12 -0.2993 -0.9212 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A18 compound treatment 338270.0 -15900.0 -0.11 305010.0 -12100.0 -0.09 -0.1379 -0.9949 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A19 compound treatment 254880.0 -99300.0 -0.67 272700.0 -44400.0 -0.32 -0.7017 -0.9432 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A20 compound treatment 221830.0 -132000.0 -0.89 187950.0 -129000.0 -0.93 -1.2934 -0.9998 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A21 compound treatment 126420.0 -228000.0 -1.54 146980.0 -170000.0 -1.23 -1.959 -0.9939 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A22 compound treatment 296910.0 -57300.0 -0.39 274320.0 -42800.0 -0.31 -0.4926 -0.9939 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A23 compound treatment 331840.0 -22300.0 -0.15 259900.0 -57200.0 -0.41 -0.3995 -0.9064 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 A24 compound treatment 271280.0 -82900.0 -0.56 234100.0 -83000.0 -0.6 -0.8209 -0.9994 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B01 compound treatment 153500.0 -201000.0 -1.36 140200.0 -177000.0 -1.28 -1.8643 -0.9996 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B02 compound treatment 408680.0 54500.0 0.37 396710.0 79600.0 0.58 0.6679 0.9766 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B03 compound treatment 335420.0 -18800.0 -0.13 385650.0 68500.0 0.5 0.2613 0.5102 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B04 compound treatment 309600.0 -44600.0 -0.3 371310.0 54200.0 0.39 0.0645 0.1304 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B05 compound treatment 407160.0 53000.0 0.36 284830.0 -32300.0 -0.23 0.0879 0.2057 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B06 compound treatment 355750.0 1580.0 0.01 247810.0 -69300.0 -0.5 -0.3472 -0.6919 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B07 compound treatment 281680.0 -72500.0 -0.49 323900.0 6790.0 0.05 -0.3116 -0.633 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B08 compound treatment 182360.0 -172000.0 -1.16 187200.0 -130000.0 -0.94 -1.4858 -0.9945 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B09 compound treatment 232120.0 -122000.0 -0.82 241330.0 -75800.0 -0.55 -0.971 -0.9804 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B10 compound treatment 236060.0 -118000.0 -0.8 291700.0 -25400.0 -0.18 -0.6944 -0.8479 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B11 compound treatment 384480.0 30300.0 0.2 336260.0 19200.0 0.14 0.2428 0.9819 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B12 compound treatment 223200.0 -131000.0 -0.88 271630.0 -45500.0 -0.33 -0.8585 -0.9093 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B13 mock treatment 402630.0 48500.0 0.33 227220.0 -89900.0 -0.65 -0.2286 -0.3138 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B14 mock treatment 387450.0 33300.0 0.22 311610.0 -5500.0 -0.04 0.1309 0.573 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B15 compound treatment 352020.0 -2150.0 -0.01 387930.0 70800.0 0.51 0.3522 0.6868 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B16 compound treatment 332870.0 -21300.0 -0.14 388550.0 71400.0 0.52 0.2639 0.4916 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B17 compound treatment 359620.0 5450.0 0.04 316440.0 -669.0 0.0 0.0226 0.6089 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B18 compound treatment 291280.0 -62900.0 -0.42 395330.0 78200.0 0.57 0.0999 0.1411 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B19 compound treatment 156410.0 -198000.0 -1.34 172960.0 -144000.0 -1.04 -1.6827 -0.9925 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B20 compound treatment 311860.0 -42300.0 -0.29 262890.0 -54200.0 -0.39 -0.4797 -0.9879 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B21 compound treatment 249890.0 -104000.0 -0.7 296640.0 -20500.0 -0.15 -0.603 -0.8375 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B22 compound treatment 315970.0 -38200.0 -0.26 278560.0 -38500.0 -0.28 -0.3798 -0.9992 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B23 compound treatment 380640.0 26500.0 0.18 362950.0 45800.0 0.33 0.3611 0.9579 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 B24 compound treatment 336870.0 -17300.0 -0.12 291200.0 -25900.0 -0.19 -0.2153 -0.9741 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C01 compound treatment 360230.0 6060.0 0.04 321830.0 4720.0 0.03 0.0531 0.996 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C02 compound treatment 351130.0 -3040.0 -0.02 286590.0 -30500.0 -0.22 -0.1707 -0.7695 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C03 compound treatment 190320.0 -164000.0 -1.11 188290.0 -129000.0 -0.93 -1.4422 -0.9964 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C04 compound treatment 7270.0 -347000.0 -2.34 8650.0 -308000.0 -2.23 -3.2363 -0.9997 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C05 compound treatment 195600.0 -159000.0 -1.07 209230.0 -108000.0 -0.78 -1.3098 -0.9879 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C06 compound treatment 224340.0 -130000.0 -0.88 249170.0 -67900.0 -0.49 -0.9681 -0.9626 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C07 compound treatment 363610.0 9440.0 0.06 290570.0 -26500.0 -0.19 -0.0907 -0.4483 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C08 compound treatment 159480.0 -195000.0 -1.32 123290.0 -194000.0 -1.4 -1.9223 -0.9995 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C09 compound treatment 252480.0 -102000.0 -0.69 328930.0 11800.0 0.09 -0.4253 -0.6143 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C10 compound treatment 46340.0 -308000.0 -2.08 124440.0 -193000.0 -1.39 -2.457 -0.9811 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C11 mock treatment 265340.0 -88800.0 -0.6 331710.0 14600.0 0.11 -0.3497 -0.5738 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C12 mock treatment 360350.0 6180.0 0.04 370020.0 52900.0 0.38 0.3004 0.7796 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C13 compound treatment 354270.0 99.7 0.0 371520.0 54400.0 0.39 0.279 0.7083 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C14 compound treatment 322560.0 -31600.0 -0.21 323380.0 6270.0 0.05 -0.1189 -0.5446 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C15 mock treatment 328850.0 -25300.0 -0.17 334680.0 17600.0 0.13 -0.031 -0.1456 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C16 mock treatment 339540.0 -14600.0 -0.1 341600.0 24500.0 0.18 0.0555 0.2732 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C17 compound treatment 296040.0 -58100.0 -0.39 271310.0 -45800.0 -0.33 -0.5122 -0.9964 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C18 compound treatment 146160.0 -208000.0 -1.41 167840.0 -149000.0 -1.08 -1.7579 -0.9916 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C19 compound treatment 318010.0 -36200.0 -0.24 273340.0 -43800.0 -0.32 -0.3968 -0.9918 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C20 compound treatment 326090.0 -28100.0 -0.19 261600.0 -55500.0 -0.4 -0.4183 -0.9413 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C21 compound treatment 189870.0 -164000.0 -1.11 252800.0 -64300.0 -0.47 -1.1142 -0.9255 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C22 compound treatment 331100.0 -23100.0 -0.16 311370.0 -5740.0 -0.04 -0.1396 -0.8653 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C23 compound treatment 262570.0 -91600.0 -0.62 234200.0 -82900.0 -0.6 -0.862 -0.9999 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 C24 compound treatment 313850.0 -40300.0 -0.27 244210.0 -72900.0 -0.53 -0.5658 -0.9527 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D01 compound treatment 312030.0 -42100.0 -0.28 248970.0 -68100.0 -0.49 -0.5501 -0.9659 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D02 compound treatment 177330.0 -177000.0 -1.19 167520.0 -150000.0 -1.08 -1.6106 -0.9988 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D03 compound treatment 380550.0 26400.0 0.18 297030.0 -20100.0 -0.15 0.0233 0.1011 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D04 compound treatment 252380.0 -102000.0 -0.69 293230.0 -23900.0 -0.17 -0.6086 -0.8581 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D05 compound treatment 340240.0 -13900.0 -0.09 390460.0 73400.0 0.53 0.3089 0.5728 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D06 compound treatment 172380.0 -182000.0 -1.23 179520.0 -138000.0 -1.0 -1.5728 -0.9946 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D07 compound treatment 400520.0 46300.0 0.31 270880.0 -46200.0 -0.33 -0.0152 -0.0331 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D08 compound treatment 313480.0 -40700.0 -0.27 339300.0 22200.0 0.16 -0.0808 -0.2538 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D09 compound treatment 253960.0 -100000.0 -0.68 261920.0 -55200.0 -0.4 -0.7613 -0.9683 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D10 compound treatment 185890.0 -168000.0 -1.14 180130.0 -137000.0 -0.99 -1.5052 -0.9977 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D11 mock treatment 402930.0 48800.0 0.33 330100.0 13000.0 0.09 0.2995 0.874 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D12 mock treatment 345330.0 -8840.0 -0.06 379240.0 62100.0 0.45 0.2758 0.6079 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D13 compound treatment 339060.0 -15100.0 -0.1 385600.0 68500.0 0.5 0.2784 0.55 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D14 compound treatment 387470.0 33300.0 0.23 315230.0 -1880.0 -0.01 0.1495 0.6632 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D15 mock treatment 383850.0 29700.0 0.2 319540.0 2430.0 0.02 0.1542 0.7662 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D16 mock treatment 387610.0 33400.0 0.23 364640.0 47500.0 0.34 0.4031 0.9792 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D17 compound treatment 421050.0 66900.0 0.45 293530.0 -23600.0 -0.17 0.1988 0.4116 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D18 compound treatment 299750.0 -54400.0 -0.37 279260.0 -37800.0 -0.27 -0.4537 -0.9895 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D19 compound treatment 297140.0 -57000.0 -0.39 294330.0 -22800.0 -0.16 -0.3891 -0.9283 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D20 compound treatment 321920.0 -32300.0 -0.22 275150.0 -42000.0 -0.3 -0.3689 -0.9867 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D21 compound treatment 420230.0 66100.0 0.45 324190.0 7080.0 0.05 0.3519 0.7832 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D22 compound treatment 146200.0 -208000.0 -1.41 148290.0 -169000.0 -1.22 -1.8578 -0.9976 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D23 compound treatment 292100.0 -62100.0 -0.42 286000.0 -31100.0 -0.23 -0.4558 -0.9575 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 D24 compound treatment 140660.0 -214000.0 -1.44 130780.0 -186000.0 -1.35 -1.9739 -0.9994 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E01 mock treatment 356670.0 2500.0 0.02 336860.0 19800.0 0.14 0.113 0.7852 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E02 mock treatment 288000.0 -66200.0 -0.45 400910.0 83800.0 0.61 0.1128 0.1497 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E03 compound treatment 437760.0 83600.0 0.56 262530.0 -54600.0 -0.4 0.12 0.1741 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E04 compound treatment 375890.0 21700.0 0.15 305280.0 -11800.0 -0.09 0.0432 0.2544 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E05 compound treatment 372960.0 18800.0 0.13 372800.0 55700.0 0.4 0.3748 0.8869 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E06 compound treatment 256380.0 -97800.0 -0.66 148010.0 -169000.0 -1.22 -1.3328 -0.9581 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E07 compound treatment 300320.0 -53900.0 -0.36 278400.0 -38700.0 -0.28 -0.4554 -0.9917 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E08 compound treatment 346950.0 -7220.0 -0.05 357760.0 40700.0 0.29 0.1736 0.5819 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E09 mock treatment 305760.0 -48400.0 -0.33 338610.0 21500.0 0.16 -0.1212 -0.3347 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E10 mock treatment 401280.0 47100.0 0.32 388670.0 71600.0 0.52 0.5914 0.9727 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E11 compound treatment 415090.0 60900.0 0.41 376810.0 59700.0 0.43 0.5967 0.9997 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E12 compound treatment 300750.0 -53400.0 -0.36 325280.0 8170.0 0.06 -0.2134 -0.5834 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E13 compound treatment 365700.0 11500.0 0.08 385320.0 68200.0 0.49 0.4042 0.8087 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E14 compound treatment 390720.0 36500.0 0.25 315250.0 -1860.0 -0.01 0.1651 0.6676 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E15 compound treatment 214240.0 -140000.0 -0.95 241960.0 -75100.0 -0.54 -1.0532 -0.9655 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E16 compound treatment 316480.0 -37700.0 -0.25 335940.0 18800.0 0.14 -0.0837 -0.2897 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E17 mock treatment 313600.0 -40600.0 -0.27 357600.0 40500.0 0.29 0.0134 0.0335 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E18 mock treatment 380010.0 25800.0 0.17 267420.0 -49700.0 -0.36 -0.1309 -0.3274 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E19 compound treatment 310050.0 -44100.0 -0.3 321120.0 4010.0 0.03 -0.1903 -0.6352 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E20 compound treatment 267790.0 -86400.0 -0.58 283860.0 -33200.0 -0.24 -0.5829 -0.9233 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E21 compound treatment 329660.0 -24500.0 -0.17 288480.0 -28600.0 -0.21 -0.2636 -0.9938 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E22 compound treatment 374180.0 20000.0 0.14 293920.0 -23200.0 -0.17 -0.0231 -0.1071 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E23 compound treatment 310930.0 -43200.0 -0.29 317880.0 771.0 0.01 -0.2026 -0.6935 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 E24 compound treatment 339130.0 -15000.0 -0.1 330880.0 13800.0 0.1 -0.0014 -0.0096 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F01 mock treatment 421640.0 67500.0 0.46 379680.0 62600.0 0.45 0.6426 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F02 mock treatment 252250.0 -102000.0 -0.69 313040.0 -4070.0 -0.03 -0.5078 -0.7367 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F03 compound treatment 353240.0 -930.0 -0.01 330900.0 13800.0 0.1 0.0661 0.6613 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F04 compound treatment 237620.0 -117000.0 -0.79 199390.0 -118000.0 -0.85 -1.1594 -0.9992 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F05 compound treatment 295710.0 -58500.0 -0.4 262370.0 -54700.0 -0.4 -0.5595 -1.0 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F06 compound treatment 411780.0 57600.0 0.39 333520.0 16400.0 0.12 0.3593 0.8827 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F07 compound treatment 181120.0 -173000.0 -1.17 185120.0 -132000.0 -0.96 -1.5024 -0.995 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F08 compound treatment 235860.0 -118000.0 -0.8 229560.0 -87500.0 -0.63 -1.0134 -0.9934 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F09 mock treatment 266580.0 -87600.0 -0.59 414300.0 97200.0 0.7 0.079 0.0859 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F10 mock treatment 331580.0 -22600.0 -0.15 418100.0 101000.0 0.73 0.409 0.5477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F11 compound treatment 361600.0 7430.0 0.05 245370.0 -71700.0 -0.52 -0.3317 -0.6358 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F12 compound treatment 122240.0 -232000.0 -1.57 187740.0 -129000.0 -0.94 -1.7703 -0.9697 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F13 compound treatment 348330.0 -5840.0 -0.04 369310.0 52200.0 0.38 0.2393 0.6298 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F14 compound treatment 285370.0 -68800.0 -0.46 298020.0 -19100.0 -0.14 -0.4264 -0.8793 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F15 compound treatment 271610.0 -82600.0 -0.56 289520.0 -27600.0 -0.2 -0.5357 -0.9041 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F16 compound treatment 372230.0 18100.0 0.12 345640.0 28500.0 0.21 0.2323 0.9685 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F17 mock treatment 339720.0 -14500.0 -0.1 322890.0 5780.0 0.04 -0.0394 -0.3713 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F18 mock treatment 403260.0 49100.0 0.33 340980.0 23900.0 0.17 0.3567 0.9538 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F19 compound treatment 171370.0 -183000.0 -1.24 210760.0 -106000.0 -0.77 -1.4178 -0.9741 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F20 compound treatment 175800.0 -178000.0 -1.21 190660.0 -126000.0 -0.92 -1.4995 -0.9908 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F21 compound treatment 246660.0 -108000.0 -0.73 214130.0 -103000.0 -0.75 -1.0408 -0.9999 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F22 compound treatment 163550.0 -191000.0 -1.29 143310.0 -174000.0 -1.26 -1.8004 -0.9999 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F23 compound treatment 386400.0 32200.0 0.22 288260.0 -28800.0 -0.21 0.0063 0.0209 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 F24 compound treatment 336640.0 -17500.0 -0.12 250160.0 -66900.0 -0.48 -0.4264 -0.8548 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G01 compound treatment 216220.0 -138000.0 -0.93 271210.0 -45900.0 -0.33 -0.894 -0.9035 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G02 compound treatment 292960.0 -61200.0 -0.41 387760.0 70700.0 0.51 0.0692 0.1052 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G03 mock treatment 365250.0 11100.0 0.07 268320.0 -48800.0 -0.35 -0.1968 -0.5451 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G04 mock treatment 365090.0 10900.0 0.07 311300.0 -5810.0 -0.04 0.0224 0.2642 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G05 compound treatment 383400.0 29200.0 0.2 294880.0 -22200.0 -0.16 0.0259 0.1016 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G06 compound treatment 382210.0 28000.0 0.19 259840.0 -57300.0 -0.41 -0.1592 -0.3492 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G07 compound treatment 271320.0 -82900.0 -0.56 295380.0 -21700.0 -0.16 -0.5071 -0.872 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G08 compound treatment 377770.0 23600.0 0.16 376710.0 59600.0 0.43 0.4178 0.9084 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G09 compound treatment 397360.0 43200.0 0.29 255160.0 -61900.0 -0.45 -0.1107 -0.207 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G10 compound treatment 375320.0 21100.0 0.14 456660.0 140000.0 1.01 0.8154 0.7992 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G11 compound treatment 436980.0 82800.0 0.56 440970.0 124000.0 0.9 1.0297 0.9742 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G12 compound treatment 199800.0 -154000.0 -1.04 193810.0 -123000.0 -0.89 -1.3687 -0.997 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G13 compound treatment 381760.0 27600.0 0.19 347100.0 30000.0 0.22 0.2853 0.9971 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G14 compound treatment 396080.0 41900.0 0.28 308660.0 -8450.0 -0.06 0.157 0.5419 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G15 compound treatment 397680.0 43500.0 0.29 309210.0 -7900.0 -0.06 0.1674 0.5591 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G16 compound treatment 308760.0 -45400.0 -0.31 334280.0 17200.0 0.12 -0.1291 -0.3899 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G17 compound treatment 314350.0 -39800.0 -0.27 270290.0 -46800.0 -0.34 -0.4299 -0.9935 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G18 compound treatment 186690.0 -167000.0 -1.13 164600.0 -153000.0 -1.1 -1.5808 -0.9999 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G19 mock treatment 372270.0 18100.0 0.12 323390.0 6280.0 0.05 0.1186 0.9092 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G20 mock treatment 413830.0 59700.0 0.4 346690.0 29600.0 0.21 0.4365 0.9562 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G21 compound treatment 397860.0 43700.0 0.3 317920.0 811.0 0.01 0.2129 0.721 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G22 compound treatment 383920.0 29700.0 0.2 281320.0 -35800.0 -0.26 -0.0411 -0.1252 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G23 compound treatment 408560.0 54400.0 0.37 288600.0 -28500.0 -0.21 0.1139 0.2703 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 G24 compound treatment 285760.0 -68400.0 -0.46 288260.0 -28800.0 -0.21 -0.4745 -0.9355 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H01 compound treatment 261800.0 -92400.0 -0.62 359770.0 42700.0 0.31 -0.223 -0.3202 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H02 compound treatment 152750.0 -201000.0 -1.36 135590.0 -182000.0 -1.31 -1.8915 -0.9998 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H03 mock treatment 401480.0 47300.0 0.32 329070.0 12000.0 0.09 0.2873 0.8674 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H04 mock treatment 406080.0 51900.0 0.35 371550.0 54400.0 0.39 0.5267 0.9983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H05 compound treatment 221390.0 -133000.0 -0.9 178320.0 -139000.0 -1.0 -1.3448 -0.9984 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H06 compound treatment 186050.0 -168000.0 -1.14 129810.0 -187000.0 -1.36 -1.762 -0.9961 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H07 compound treatment 510190.0 156000.0 1.05 445210.0 128000.0 0.93 1.4011 0.998 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H08 compound treatment 426210.0 72000.0 0.49 189700.0 -127000.0 -0.92 -0.308 -0.2953 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H09 compound treatment 220090.0 -134000.0 -0.91 295930.0 -21200.0 -0.15 -0.749 -0.8152 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H10 compound treatment 326210.0 -28000.0 -0.19 355840.0 38700.0 0.28 0.0647 0.1913 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H11 compound treatment 366490.0 12300.0 0.08 240800.0 -76300.0 -0.55 -0.3317 -0.5938 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H12 compound treatment 314240.0 -39900.0 -0.27 300120.0 -17000.0 -0.12 -0.2777 -0.9367 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H13 compound treatment 406850.0 52700.0 0.36 370290.0 53200.0 0.38 0.5239 0.9992 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H14 compound treatment 372990.0 18800.0 0.13 382560.0 65500.0 0.47 0.4249 0.8662 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H15 compound treatment 330290.0 -23900.0 -0.16 402240.0 85100.0 0.62 0.3217 0.5049 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H16 compound treatment 335110.0 -19100.0 -0.13 354950.0 37800.0 0.27 0.1026 0.3391 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H17 compound treatment 381760.0 27600.0 0.19 396500.0 79400.0 0.57 0.5382 0.8908 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H18 compound treatment 370620.0 16400.0 0.11 333500.0 16400.0 0.12 0.1625 0.9995 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H19 mock treatment 339760.0 -14400.0 -0.1 287470.0 -29600.0 -0.21 -0.2206 -0.9361 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H20 mock treatment 341200.0 -13000.0 -0.09 291140.0 -26000.0 -0.19 -0.1949 -0.9397 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H21 compound treatment 317520.0 -36700.0 -0.25 288390.0 -28700.0 -0.21 -0.3221 -0.9962 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H22 compound treatment 167460.0 -187000.0 -1.26 159590.0 -158000.0 -1.14 -1.6984 -0.9987 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H23 compound treatment 407740.0 53600.0 0.36 221720.0 -95400.0 -0.69 -0.2323 -0.298 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 H24 compound treatment 259890.0 -94300.0 -0.64 197880.0 -119000.0 -0.86 -1.0607 -0.9888 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I01 compound treatment 308030.0 -46100.0 -0.31 305730.0 -11400.0 -0.08 -0.2787 -0.8643 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I02 compound treatment 369180.0 15000.0 0.1 376180.0 59100.0 0.43 0.3741 0.8512 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I03 compound treatment 360340.0 6170.0 0.04 340820.0 23700.0 0.17 0.1508 0.854 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I04 compound treatment 415000.0 60800.0 0.41 311910.0 -5200.0 -0.04 0.264 0.6397 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I05 mock treatment 356340.0 2170.0 0.01 346740.0 29600.0 0.21 0.162 0.7537 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I06 mock treatment 291800.0 -62400.0 -0.42 266620.0 -50500.0 -0.37 -0.5564 -0.9975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I07 compound treatment 289380.0 -64800.0 -0.44 224180.0 -92900.0 -0.67 -0.7852 -0.9783 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I08 compound treatment 340160.0 -14000.0 -0.09 234560.0 -82500.0 -0.6 -0.4895 -0.809 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I09 compound treatment 186340.0 -168000.0 -1.13 183400.0 -134000.0 -0.97 -1.4863 -0.9969 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I10 compound treatment 395680.0 41500.0 0.28 370480.0 53400.0 0.39 0.4715 0.9876 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I11 compound treatment 256380.0 -97800.0 -0.66 356540.0 39400.0 0.29 -0.2654 -0.3687 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I12 compound treatment 248930.0 -105000.0 -0.71 271210.0 -45900.0 -0.33 -0.7378 -0.94 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I13 compound treatment 234850.0 -119000.0 -0.81 392660.0 75600.0 0.55 -0.1834 -0.1882 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I14 compound treatment 298170.0 -56000.0 -0.38 263680.0 -53400.0 -0.39 -0.541 -0.9999 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I15 compound treatment 292640.0 -61500.0 -0.42 325650.0 8540.0 0.06 -0.2503 -0.5954 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I16 compound treatment 247270.0 -107000.0 -0.72 231240.0 -85900.0 -0.62 -0.9503 -0.9972 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I17 compound treatment 354890.0 720.0 0.0 354140.0 37000.0 0.27 0.193 0.7198 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I18 compound treatment 414990.0 60800.0 0.41 300050.0 -17100.0 -0.12 0.2033 0.4737 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I19 compound treatment 328020.0 -26200.0 -0.18 329620.0 12500.0 0.09 -0.0609 -0.3067 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I20 compound treatment 313020.0 -41200.0 -0.28 242400.0 -74700.0 -0.54 -0.579 -0.9522 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I21 mock treatment 382560.0 28400.0 0.19 307250.0 -9860.0 -0.07 0.0852 0.4162 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I22 mock treatment 384280.0 30100.0 0.2 231700.0 -85400.0 -0.62 -0.2933 -0.4507 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I23 compound treatment 370620.0 16400.0 0.11 288330.0 -28800.0 -0.21 -0.0687 -0.291 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 I24 compound treatment 311250.0 -42900.0 -0.29 295160.0 -21900.0 -0.16 -0.3174 -0.9599 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J01 compound treatment 252130.0 -102000.0 -0.69 300930.0 -16200.0 -0.12 -0.5703 -0.8155 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J02 compound treatment 336080.0 -18100.0 -0.12 388750.0 71600.0 0.52 0.2803 0.526 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J03 compound treatment 242110.0 -112000.0 -0.76 173860.0 -143000.0 -1.04 -1.2686 -0.9881 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J04 compound treatment 228590.0 -126000.0 -0.85 275520.0 -41600.0 -0.3 -0.8129 -0.9028 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J05 mock treatment 222880.0 -131000.0 -0.89 226910.0 -90200.0 -0.65 -1.089 -0.9886 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J06 mock treatment 327840.0 -26300.0 -0.18 365280.0 48200.0 0.35 0.1208 0.3085 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J07 compound treatment 143420.0 -211000.0 -1.42 151260.0 -166000.0 -1.2 -1.8559 -0.9964 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J08 compound treatment 142350.0 -212000.0 -1.43 165230.0 -152000.0 -1.1 -1.7895 -0.9915 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J09 compound treatment 189400.0 -165000.0 -1.11 236850.0 -80300.0 -0.58 -1.1981 -0.954 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J10 compound treatment 439640.0 85500.0 0.58 306660.0 -10400.0 -0.08 0.3549 0.6093 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J11 compound treatment 388270.0 34100.0 0.23 267280.0 -49800.0 -0.36 -0.0921 -0.2153 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J12 compound treatment 388650.0 34500.0 0.23 220550.0 -96600.0 -0.7 -0.3295 -0.4472 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J13 compound treatment 109990.0 -244000.0 -1.65 180290.0 -137000.0 -0.99 -1.867 -0.9702 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J14 compound treatment 348720.0 -5450.0 -0.04 292110.0 -25000.0 -0.18 -0.154 -0.8339 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J15 compound treatment 293130.0 -61000.0 -0.41 357360.0 40300.0 0.29 -0.0856 -0.1695 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J16 compound treatment 141340.0 -213000.0 -1.44 152190.0 -165000.0 -1.19 -1.861 -0.9957 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J17 compound treatment 114850.0 -239000.0 -1.62 106670.0 -210000.0 -1.52 -2.2206 -0.9996 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J18 compound treatment 261770.0 -92400.0 -0.62 373450.0 56300.0 0.41 -0.1531 -0.2053 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J19 compound treatment 389040.0 34900.0 0.24 261600.0 -55500.0 -0.4 -0.1175 -0.2523 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J20 compound treatment 384680.0 30500.0 0.21 304240.0 -12900.0 -0.09 0.0799 0.3532 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J21 mock treatment 428210.0 74000.0 0.5 356810.0 39700.0 0.29 0.557 0.9654 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J22 mock treatment 362590.0 8420.0 0.06 361650.0 44500.0 0.32 0.2682 0.8192 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J23 compound treatment 310840.0 -43300.0 -0.29 304490.0 -12600.0 -0.09 -0.2716 -0.8856 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 J24 compound treatment 290260.0 -63900.0 -0.43 247110.0 -70000.0 -0.51 -0.6637 -0.9968 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K01 compound treatment 165490.0 -189000.0 -1.27 176050.0 -141000.0 -1.02 -1.6235 -0.9939 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K02 compound treatment 371080.0 16900.0 0.11 311230.0 -5880.0 -0.04 0.0507 0.4158 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K03 compound treatment 257160.0 -97000.0 -0.66 229620.0 -87500.0 -0.63 -0.9113 -0.9999 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K04 compound treatment 291920.0 -62300.0 -0.42 176910.0 -140000.0 -1.01 -1.0151 -0.924 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K05 compound treatment 150650.0 -204000.0 -1.38 327550.0 10400.0 0.08 -0.9189 -0.6672 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K06 compound treatment 132600.0 -222000.0 -1.5 269920.0 -47200.0 -0.34 -1.3002 -0.8467 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K07 mock treatment 365160.0 11000.0 0.07 315170.0 -1940.0 -0.01 0.0426 0.5635 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K08 mock treatment 241080.0 -113000.0 -0.76 215880.0 -101000.0 -0.73 -1.0585 -0.9998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K09 compound treatment 466720.0 113000.0 0.76 431610.0 115000.0 0.83 1.1238 0.9991 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K10 compound treatment 311860.0 -42300.0 -0.29 432440.0 115000.0 0.83 0.3882 0.4399 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K11 compound treatment 384850.0 30700.0 0.21 279490.0 -37600.0 -0.27 -0.046 -0.1343 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K12 compound treatment 132240.0 -222000.0 -1.5 107840.0 -209000.0 -1.51 -2.1315 -1.0 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K13 compound treatment 302400.0 -51800.0 -0.35 388120.0 71000.0 0.51 0.1161 0.1868 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K14 compound treatment 214610.0 -140000.0 -0.94 219000.0 -98100.0 -0.71 -1.169 -0.9902 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K15 mock treatment 453280.0 99100.0 0.67 267890.0 -49200.0 -0.36 0.2216 0.2921 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K16 mock treatment 466650.0 112000.0 0.76 257840.0 -59300.0 -0.43 0.234 0.2681 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K17 compound treatment 183370.0 -171000.0 -1.15 166580.0 -151000.0 -1.09 -1.5866 -0.9996 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K18 compound treatment 9650.0 -345000.0 -2.33 8800.0 -308000.0 -2.23 -3.2242 -0.9998 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K19 compound treatment 337090.0 -17100.0 -0.12 305180.0 -11900.0 -0.09 -0.1427 -0.9898 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K20 compound treatment 352910.0 -1260.0 -0.01 392980.0 75900.0 0.55 0.3823 0.6961 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K21 compound treatment 390100.0 35900.0 0.24 387550.0 70400.0 0.51 0.5322 0.9424 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K22 compound treatment 452340.0 98200.0 0.66 320280.0 3170.0 0.02 0.4853 0.7311 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K23 mock treatment 364860.0 10700.0 0.07 279050.0 -38100.0 -0.28 -0.1437 -0.5047 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 K24 mock treatment 447520.0 93300.0 0.63 339530.0 22400.0 0.16 0.5608 0.861 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L01 compound treatment 176160.0 -178000.0 -1.2 219710.0 -97400.0 -0.71 -1.3491 -0.9676 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L02 compound treatment 180190.0 -174000.0 -1.18 120600.0 -197000.0 -1.42 -1.8371 -0.9955 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L03 compound treatment 217720.0 -136000.0 -0.92 187150.0 -130000.0 -0.94 -1.3172 -0.9999 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L04 compound treatment 272040.0 -82100.0 -0.55 394610.0 77500.0 0.56 0.0043 0.0055 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L05 compound treatment 212060.0 -142000.0 -0.96 194820.0 -122000.0 -0.89 -1.3049 -0.9992 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L06 compound treatment 179070.0 -175000.0 -1.18 270410.0 -46700.0 -0.34 -1.0756 -0.8742 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L07 mock treatment 222830.0 -131000.0 -0.89 146150.0 -171000.0 -1.24 -1.5026 -0.9867 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L08 mock treatment 430610.0 76400.0 0.52 203790.0 -113000.0 -0.82 -0.2148 -0.2216 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L09 compound treatment 337920.0 -16300.0 -0.11 133640.0 -183000.0 -1.33 -1.0168 -0.763 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L10 compound treatment 454640.0 100000.0 0.68 339360.0 22300.0 0.16 0.5939 0.8513 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L11 compound treatment 242990.0 -111000.0 -0.75 385000.0 67900.0 0.49 -0.1837 -0.2046 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L12 compound treatment 156640.0 -198000.0 -1.33 171680.0 -145000.0 -1.05 -1.6882 -0.9931 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L13 compound treatment 313540.0 -40600.0 -0.27 179760.0 -137000.0 -0.99 -0.8972 -0.8698 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L14 compound treatment 382800.0 28600.0 0.19 308880.0 -8230.0 -0.06 0.0947 0.4677 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L15 mock treatment 394350.0 40200.0 0.27 264920.0 -52200.0 -0.38 -0.0752 -0.1616 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L16 mock treatment 429660.0 75500.0 0.51 390930.0 73800.0 0.53 0.7385 0.9997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L17 compound treatment 481840.0 128000.0 0.86 459480.0 142000.0 1.03 1.3387 0.9961 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L18 compound treatment 176980.0 -177000.0 -1.2 141470.0 -176000.0 -1.27 -1.7456 -0.9995 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L19 compound treatment 354800.0 630.0 0.0 292870.0 -24200.0 -0.18 -0.1211 -0.6898 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L20 compound treatment 420700.0 66500.0 0.45 387700.0 70600.0 0.51 0.6792 0.998 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L21 compound treatment 380750.0 26600.0 0.18 257010.0 -60100.0 -0.44 -0.1806 -0.3838 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L22 compound treatment 453540.0 99400.0 0.67 360820.0 43700.0 0.32 0.6985 0.9411 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L23 mock treatment 418510.0 64300.0 0.43 375380.0 58300.0 0.42 0.6057 0.9999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 L24 mock treatment 359810.0 5640.0 0.04 418340.0 101000.0 0.73 0.5451 0.7429 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M01 compound treatment 318400.0 -35800.0 -0.24 308840.0 -8270.0 -0.06 -0.2132 -0.8564 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M02 compound treatment 205230.0 -149000.0 -1.01 381820.0 64700.0 0.47 -0.3804 -0.3427 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M03 compound treatment 224050.0 -130000.0 -0.88 217050.0 -100000.0 -0.72 -1.1339 -0.9954 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M04 compound treatment 399210.0 45000.0 0.3 459920.0 143000.0 1.03 0.9462 0.878 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M05 compound treatment 145520.0 -209000.0 -1.41 138940.0 -178000.0 -1.29 -1.9089 -0.999 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M06 compound treatment 385610.0 31400.0 0.21 195290.0 -122000.0 -0.88 -0.4733 -0.5218 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M07 compound treatment 252800.0 -101000.0 -0.68 281280.0 -35800.0 -0.26 -0.6677 -0.9117 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M08 compound treatment 412400.0 58200.0 0.39 217410.0 -99700.0 -0.72 -0.2321 -0.2824 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M09 mock treatment 485980.0 132000.0 0.89 382810.0 65700.0 0.48 0.9661 0.9568 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M10 mock treatment 477560.0 123000.0 0.83 421020.0 104000.0 0.75 1.1214 0.9987 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M11 compound treatment 141800.0 -212000.0 -1.43 137470.0 -180000.0 -1.3 -1.9342 -0.9988 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M12 compound treatment 7400.0 -347000.0 -2.34 14240.0 -303000.0 -2.19 -3.2071 -0.9994 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M13 mock treatment 388480.0 34300.0 0.23 403790.0 86700.0 0.63 0.6076 0.9083 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M14 mock treatment 480860.0 127000.0 0.86 335280.0 18200.0 0.13 0.6983 0.8063 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M15 compound treatment 427480.0 73300.0 0.5 290410.0 -26700.0 -0.19 0.2136 0.4017 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M16 compound treatment 466300.0 112000.0 0.76 264720.0 -52400.0 -0.38 0.2676 0.3158 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M17 compound treatment 422810.0 68600.0 0.46 371870.0 54800.0 0.4 0.6083 0.9969 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M18 compound treatment 442960.0 88800.0 0.6 384800.0 67700.0 0.49 0.7707 0.995 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M19 compound treatment 341700.0 -12500.0 -0.08 354840.0 37700.0 0.27 0.1336 0.4672 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M20 compound treatment 378360.0 24200.0 0.16 242770.0 -74300.0 -0.54 -0.2649 -0.4711 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M21 compound treatment 436070.0 81900.0 0.55 291120.0 -26000.0 -0.19 0.2583 0.4419 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M22 compound treatment 408080.0 53900.0 0.36 376810.0 59700.0 0.43 0.5632 0.9964 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M23 compound treatment 449470.0 95300.0 0.64 292390.0 -24700.0 -0.18 0.3288 0.492 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 M24 compound treatment 373120.0 18900.0 0.13 234010.0 -83100.0 -0.6 -0.3348 -0.5444 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N01 compound treatment 223480.0 -131000.0 -0.88 296760.0 -20300.0 -0.15 -0.7286 -0.8138 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N02 compound treatment 420920.0 66700.0 0.45 274900.0 -42200.0 -0.31 0.1029 0.1888 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N03 compound treatment 294240.0 -59900.0 -0.4 326100.0 8990.0 0.07 -0.2403 -0.5859 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N04 compound treatment 157120.0 -197000.0 -1.33 175800.0 -141000.0 -1.02 -1.6648 -0.9915 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N05 compound treatment 299450.0 -54700.0 -0.37 427260.0 110000.0 0.8 0.3024 0.344 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N06 compound treatment 185540.0 -169000.0 -1.14 146050.0 -171000.0 -1.24 -1.6813 -0.9991 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N07 compound treatment 292490.0 -61700.0 -0.42 298720.0 -18400.0 -0.13 -0.3888 -0.8887 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N08 compound treatment 249510.0 -105000.0 -0.71 356750.0 39600.0 0.29 -0.2971 -0.3893 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N09 mock treatment 200020.0 -154000.0 -1.04 269680.0 -47400.0 -0.34 -0.9793 -0.8929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N10 mock treatment 310270.0 -43900.0 -0.3 288180.0 -28900.0 -0.21 -0.3578 -0.9855 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N11 compound treatment 369870.0 15700.0 0.11 339280.0 22200.0 0.16 0.1885 0.9798 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N12 compound treatment 184650.0 -170000.0 -1.15 139120.0 -178000.0 -1.29 -1.721 -0.9983 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N13 mock treatment 460410.0 106000.0 0.72 209380.0 -108000.0 -0.78 -0.0438 -0.0414 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N14 mock treatment 343580.0 -10600.0 -0.07 331860.0 14800.0 0.11 0.0249 0.1938 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N15 compound treatment 52250.0 -302000.0 -2.04 116890.0 -200000.0 -1.45 -2.4674 -0.986 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N16 compound treatment 206850.0 -147000.0 -1.0 200690.0 -116000.0 -0.84 -1.2998 -0.9966 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N17 compound treatment 409920.0 55700.0 0.38 293010.0 -24100.0 -0.17 0.143 0.3445 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N18 compound treatment 224640.0 -130000.0 -0.88 165730.0 -151000.0 -1.1 -1.3937 -0.9938 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N19 compound treatment 391430.0 37300.0 0.25 391680.0 74600.0 0.54 0.5597 0.9397 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N20 compound treatment 172120.0 -182000.0 -1.23 159320.0 -158000.0 -1.14 -1.6775 -0.9993 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N21 compound treatment 316850.0 -37300.0 -0.25 246950.0 -70200.0 -0.51 -0.5374 -0.9478 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N22 compound treatment 326120.0 -28100.0 -0.19 224740.0 -92400.0 -0.67 -0.6068 -0.8731 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N23 compound treatment 319920.0 -34300.0 -0.23 301030.0 -16100.0 -0.12 -0.2459 -0.9494 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 N24 compound treatment 366680.0 12500.0 0.08 237670.0 -79400.0 -0.58 -0.3469 -0.5968 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O01 compound treatment 222420.0 -132000.0 -0.89 180400.0 -137000.0 -0.99 -1.3292 -0.9986 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O02 compound treatment 146030.0 -208000.0 -1.41 126420.0 -191000.0 -1.38 -1.9705 -1.0 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O03 compound treatment 342290.0 -11900.0 -0.08 246800.0 -70300.0 -0.51 -0.4167 -0.8086 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O04 compound treatment 243360.0 -111000.0 -0.75 212170.0 -105000.0 -0.76 -1.0666 -1.0 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O05 compound treatment 396570.0 42400.0 0.29 391540.0 74400.0 0.54 0.5836 0.9563 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O06 compound treatment 232960.0 -121000.0 -0.82 355140.0 38000.0 0.28 -0.3844 -0.4449 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O07 compound treatment 356320.0 2150.0 0.01 253920.0 -63200.0 -0.46 -0.3132 -0.6843 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O08 compound treatment 238730.0 -115000.0 -0.78 178210.0 -139000.0 -1.01 -1.2625 -0.9921 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O09 compound treatment 256860.0 -97300.0 -0.66 230410.0 -86700.0 -0.63 -0.9087 -0.9997 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O10 compound treatment 315970.0 -38200.0 -0.26 241240.0 -75900.0 -0.55 -0.5709 -0.9407 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O11 mock treatment 216990.0 -137000.0 -0.93 350300.0 33200.0 0.24 -0.4855 -0.5071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O12 mock treatment 333620.0 -20600.0 -0.14 220420.0 -96700.0 -0.7 -0.5931 -0.8312 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O13 compound treatment 349400.0 -4770.0 -0.03 298240.0 -18900.0 -0.14 -0.1194 -0.8506 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O14 compound treatment 369810.0 15600.0 0.11 284370.0 -32700.0 -0.24 -0.0929 -0.3578 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O15 compound treatment 126520.0 -228000.0 -1.54 139250.0 -178000.0 -1.29 -1.9981 -0.9961 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O16 compound treatment 321120.0 -33100.0 -0.22 234480.0 -82600.0 -0.6 -0.5809 -0.9098 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O17 compound treatment 228130.0 -126000.0 -0.85 226900.0 -90200.0 -0.65 -1.0639 -0.9914 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O18 compound treatment 224900.0 -129000.0 -0.87 199720.0 -117000.0 -0.85 -1.2185 -0.9999 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O19 compound treatment 266760.0 -87400.0 -0.59 224370.0 -92700.0 -0.67 -0.8923 -0.998 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O20 compound treatment 292650.0 -61500.0 -0.42 263870.0 -53200.0 -0.39 -0.5664 -0.9993 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O21 compound treatment 268480.0 -85700.0 -0.58 227110.0 -90000.0 -0.65 -0.8701 -0.9983 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O22 compound treatment 239150.0 -115000.0 -0.78 336580.0 19500.0 0.14 -0.4499 -0.5696 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O23 compound treatment 321500.0 -32700.0 -0.22 237920.0 -79200.0 -0.57 -0.5614 -0.914 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 O24 compound treatment 259750.0 -94400.0 -0.64 259600.0 -57500.0 -0.42 -0.7455 -0.9786 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P01 compound treatment 342310.0 -11900.0 -0.08 302370.0 -14700.0 -0.11 -0.1321 -0.99 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P02 compound treatment 194770.0 -159000.0 -1.08 282490.0 -34600.0 -0.25 -0.9388 -0.849 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P03 compound treatment 299930.0 -54200.0 -0.37 185290.0 -132000.0 -0.95 -0.9339 -0.9136 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P04 compound treatment 272710.0 -81500.0 -0.55 188580.0 -129000.0 -0.93 -1.0471 -0.9686 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P05 compound treatment 66640.0 -288000.0 -1.94 142680.0 -174000.0 -1.26 -2.2666 -0.9782 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P06 compound treatment 220710.0 -133000.0 -0.9 164990.0 -152000.0 -1.1 -1.4163 -0.9951 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P07 compound treatment 269890.0 -84300.0 -0.57 190670.0 -126000.0 -0.92 -1.0499 -0.9739 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P08 compound treatment 211530.0 -143000.0 -0.96 184540.0 -133000.0 -0.96 -1.3601 -1.0 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P09 compound treatment 192920.0 -161000.0 -1.09 213440.0 -104000.0 -0.75 -1.3011 -0.9834 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P10 compound treatment 199270.0 -155000.0 -1.05 162740.0 -154000.0 -1.12 -1.5302 -0.9995 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P11 mock treatment 210820.0 -143000.0 -0.97 237760.0 -79300.0 -0.57 -1.0911 -0.9689 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P12 mock treatment 169810.0 -184000.0 -1.25 220040.0 -97100.0 -0.7 -1.3777 -0.9633 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P13 compound treatment 211230.0 -143000.0 -0.97 202450.0 -115000.0 -0.83 -1.2698 -0.9972 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P14 compound treatment 89460.0 -265000.0 -1.79 104260.0 -213000.0 -1.54 -2.3542 -0.9972 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P15 compound treatment 223530.0 -131000.0 -0.88 229460.0 -87600.0 -0.63 -1.0728 -0.9869 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P16 compound treatment 220970.0 -133000.0 -0.9 209510.0 -108000.0 -0.78 -1.1872 -0.9974 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P17 compound treatment 232490.0 -122000.0 -0.82 203520.0 -114000.0 -0.82 -1.1628 -1.0 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P18 compound treatment 214570.0 -140000.0 -0.94 199590.0 -118000.0 -0.85 -1.2685 -0.9987 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P19 compound treatment 131230.0 -223000.0 -1.51 129870.0 -187000.0 -1.36 -2.0236 -0.9986 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P20 compound treatment 104930.0 -249000.0 -1.68 121500.0 -196000.0 -1.42 -2.1921 -0.9963 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P21 compound treatment 107860.0 -246000.0 -1.66 113410.0 -204000.0 -1.47 -2.2195 -0.9982 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P22 compound treatment 87080.0 -267000.0 -1.8 90970.0 -226000.0 -1.64 -2.4336 -0.9988 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P23 compound treatment 202620.0 -152000.0 -1.02 159840.0 -157000.0 -1.14 -1.5291 -0.9986 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2095 P24 compound treatment 102720.0 -251000.0 -1.7 89130.0 -228000.0 -1.65 -2.3683 -0.9999 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A01 compound treatment 225010.0 -103000.0 -0.7 378650.0 64300.0 0.47 -0.1637 -0.1953 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A02 compound treatment 354890.0 26700.0 0.18 364610.0 50300.0 0.36 0.3849 0.9477 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A03 compound treatment 105960.0 -222000.0 -1.5 173440.0 -141000.0 -1.02 -1.7829 -0.9823 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A04 compound treatment 274850.0 -53300.0 -0.36 343900.0 29600.0 0.21 -0.1035 -0.247 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A05 compound treatment 275900.0 -52300.0 -0.35 254090.0 -60300.0 -0.44 -0.5582 -0.9945 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A06 compound treatment 172160.0 -156000.0 -1.05 165320.0 -149000.0 -1.08 -1.5082 -0.9999 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A07 compound treatment 148030.0 -180000.0 -1.22 115300.0 -199000.0 -1.44 -1.8795 -0.9965 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A08 compound treatment 324800.0 -3370.0 -0.02 286110.0 -28200.0 -0.2 -0.1606 -0.7812 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A09 compound treatment 300590.0 -27600.0 -0.19 299440.0 -14900.0 -0.11 -0.2081 -0.9662 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A10 compound treatment 305800.0 -22400.0 -0.15 307630.0 -6710.0 -0.05 -0.1413 -0.8896 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A11 compound treatment 335290.0 7120.0 0.05 359000.0 44700.0 0.32 0.2626 0.8034 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A12 compound treatment 379040.0 50900.0 0.34 274340.0 -40000.0 -0.29 0.0383 0.0851 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A13 mock treatment 276800.0 -51400.0 -0.35 296700.0 -17600.0 -0.13 -0.3358 -0.9078 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A14 mock treatment 370210.0 42000.0 0.28 284690.0 -29700.0 -0.21 0.049 0.1377 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A15 compound treatment 241320.0 -86900.0 -0.59 338510.0 24200.0 0.17 -0.2913 -0.4757 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A16 compound treatment 135840.0 -192000.0 -1.3 125340.0 -189000.0 -1.37 -1.8864 -0.9997 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A17 compound treatment 280710.0 -47500.0 -0.32 374510.0 60200.0 0.44 0.0812 0.1501 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A18 compound treatment 154500.0 -174000.0 -1.17 152640.0 -162000.0 -1.17 -1.6575 -1.0 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A19 compound treatment 258720.0 -69500.0 -0.47 331010.0 16700.0 0.12 -0.2465 -0.5088 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A20 compound treatment 254210.0 -74000.0 -0.5 378690.0 64300.0 0.47 -0.024 -0.0352 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A21 compound treatment 210280.0 -118000.0 -0.8 301060.0 -13300.0 -0.1 -0.6313 -0.7868 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A22 compound treatment 246400.0 -81800.0 -0.55 301390.0 -13000.0 -0.09 -0.457 -0.8155 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A23 compound treatment 268360.0 -59800.0 -0.4 275760.0 -38600.0 -0.28 -0.4833 -0.9837 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 A24 compound treatment 287760.0 -40400.0 -0.27 222080.0 -92300.0 -0.67 -0.6654 -0.9221 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B01 compound treatment 318880.0 -9290.0 -0.06 327130.0 12800.0 0.09 0.021 0.1881 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B02 compound treatment 263400.0 -64800.0 -0.44 255460.0 -58900.0 -0.43 -0.6109 -0.9999 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B03 compound treatment 221150.0 -107000.0 -0.72 238120.0 -76200.0 -0.55 -0.9015 -0.9911 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B04 compound treatment 395520.0 67300.0 0.46 334110.0 19800.0 0.14 0.4229 0.8866 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B05 compound treatment 270650.0 -57500.0 -0.39 379520.0 65200.0 0.47 0.0588 0.0961 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B06 compound treatment 239270.0 -88900.0 -0.6 308760.0 -5580.0 -0.04 -0.4534 -0.753 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B07 compound treatment 308740.0 -19400.0 -0.13 365820.0 51500.0 0.37 0.1706 0.4319 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B08 compound treatment 423810.0 95600.0 0.65 351640.0 37300.0 0.27 0.6478 0.925 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B09 compound treatment 385840.0 57700.0 0.39 314360.0 15.2 0.0 0.2756 0.7073 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B10 compound treatment 366560.0 38400.0 0.26 326260.0 11900.0 0.09 0.2444 0.8941 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B11 compound treatment 330680.0 2510.0 0.02 340210.0 25900.0 0.19 0.1444 0.7679 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B12 compound treatment 254400.0 -73800.0 -0.5 278500.0 -35800.0 -0.26 -0.536 -0.9537 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B13 mock treatment 306630.0 -21500.0 -0.15 314160.0 -185.0 0.0 -0.1039 -0.7136 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B14 mock treatment 368920.0 40700.0 0.28 395410.0 81100.0 0.59 0.6096 0.9405 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B15 compound treatment 405140.0 77000.0 0.52 358040.0 43700.0 0.32 0.5914 0.9716 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B16 compound treatment 352430.0 24300.0 0.16 348730.0 34400.0 0.25 0.2919 0.9794 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B17 compound treatment 389130.0 61000.0 0.41 405460.0 91100.0 0.66 0.7576 0.9743 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B18 compound treatment 195740.0 -132000.0 -0.89 123770.0 -191000.0 -1.38 -1.6082 -0.978 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B19 compound treatment 348560.0 20400.0 0.14 330210.0 15900.0 0.11 0.1786 0.9959 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B20 compound treatment 226900.0 -101000.0 -0.68 275750.0 -38600.0 -0.28 -0.6814 -0.9219 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B21 compound treatment 350750.0 22600.0 0.15 334730.0 20400.0 0.15 0.2122 0.9999 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B22 compound treatment 272000.0 -56200.0 -0.38 287940.0 -26400.0 -0.19 -0.4036 -0.9496 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B23 compound treatment 362180.0 34000.0 0.23 396680.0 82300.0 0.6 0.5839 0.9141 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 B24 compound treatment 246130.0 -82000.0 -0.55 358240.0 43900.0 0.32 -0.1673 -0.2618 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C01 compound treatment 306240.0 -21900.0 -0.15 370180.0 55800.0 0.4 0.181 0.4204 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C02 compound treatment 304530.0 -23600.0 -0.16 291310.0 -23000.0 -0.17 -0.2309 -0.9998 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C03 compound treatment 181540.0 -147000.0 -0.99 222430.0 -91900.0 -0.67 -1.1711 -0.9812 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C04 compound treatment 143620.0 -185000.0 -1.25 154460.0 -160000.0 -1.16 -1.7002 -0.9993 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C05 compound treatment 141300.0 -187000.0 -1.26 159430.0 -155000.0 -1.12 -1.6858 -0.9982 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C06 compound treatment 271620.0 -56600.0 -0.38 362440.0 48100.0 0.35 -0.024 -0.0465 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C07 compound treatment 104850.0 -223000.0 -1.51 142630.0 -172000.0 -1.24 -1.946 -0.9954 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C08 compound treatment 288970.0 -39200.0 -0.26 266580.0 -47800.0 -0.35 -0.4318 -0.9913 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C09 compound treatment 199060.0 -129000.0 -0.87 200800.0 -114000.0 -0.82 -1.1981 -0.9996 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C10 compound treatment 315580.0 -12600.0 -0.09 315910.0 1570.0 0.01 -0.0522 -0.6076 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C11 mock treatment 174130.0 -154000.0 -1.04 208990.0 -105000.0 -0.76 -1.2753 -0.9883 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C12 mock treatment 315100.0 -13100.0 -0.09 331370.0 17000.0 0.12 0.0247 0.1627 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C13 compound treatment 344740.0 16600.0 0.11 261170.0 -53200.0 -0.38 -0.193 -0.4816 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C14 compound treatment 285330.0 -42800.0 -0.29 289710.0 -24600.0 -0.18 -0.3308 -0.9729 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C15 mock treatment 316220.0 -12000.0 -0.08 318140.0 3800.0 0.03 -0.0377 -0.4418 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C16 mock treatment 360920.0 32700.0 0.22 331850.0 17500.0 0.13 0.2461 0.965 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C17 compound treatment 326180.0 -1990.0 -0.01 306480.0 -7860.0 -0.06 -0.0498 -0.851 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C18 compound treatment 323410.0 -4760.0 -0.03 277230.0 -37100.0 -0.27 -0.2127 -0.7862 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C19 compound treatment 289180.0 -39000.0 -0.26 310460.0 -3880.0 -0.03 -0.2062 -0.7782 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C20 compound treatment 283420.0 -44800.0 -0.3 356820.0 42500.0 0.31 0.0036 0.0083 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C21 compound treatment 167260.0 -161000.0 -1.09 195680.0 -119000.0 -0.86 -1.3762 -0.9932 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C22 compound treatment 290000.0 -38200.0 -0.26 328480.0 14100.0 0.1 -0.11 -0.3965 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C23 compound treatment 124520.0 -204000.0 -1.38 156740.0 -158000.0 -1.14 -1.7798 -0.9957 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 C24 compound treatment 225310.0 -103000.0 -0.7 284220.0 -30100.0 -0.22 -0.6457 -0.8864 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D01 compound treatment 284760.0 -43400.0 -0.29 382280.0 67900.0 0.49 0.1403 0.245 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D02 compound treatment 90630.0 -238000.0 -1.61 97010.0 -217000.0 -1.57 -2.2474 -1.0 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D03 compound treatment 235610.0 -92600.0 -0.63 295640.0 -18700.0 -0.14 -0.538 -0.8407 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D04 compound treatment 338930.0 10800.0 0.07 282460.0 -31900.0 -0.23 -0.1118 -0.4621 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D05 compound treatment 218270.0 -110000.0 -0.74 262240.0 -52100.0 -0.38 -0.7918 -0.9507 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D06 compound treatment 272690.0 -55500.0 -0.37 360410.0 46100.0 0.33 -0.0293 -0.0584 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D07 compound treatment 312340.0 -15800.0 -0.11 272260.0 -42100.0 -0.3 -0.2911 -0.9015 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D08 compound treatment 220000.0 -108000.0 -0.73 335120.0 20800.0 0.15 -0.4105 -0.5501 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D09 compound treatment 166560.0 -162000.0 -1.09 183680.0 -131000.0 -0.95 -1.441 -0.9974 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D10 compound treatment 406610.0 78400.0 0.53 339040.0 24700.0 0.18 0.5012 0.896 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D11 mock treatment 294940.0 -33200.0 -0.22 331150.0 16800.0 0.12 -0.0728 -0.2849 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D12 mock treatment 290910.0 -37300.0 -0.25 308710.0 -5630.0 -0.04 -0.2069 -0.8111 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D13 compound treatment 307680.0 -20500.0 -0.14 257320.0 -57000.0 -0.41 -0.3898 -0.8953 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D14 compound treatment 292670.0 -35500.0 -0.24 286820.0 -27500.0 -0.2 -0.3105 -0.9957 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D15 mock treatment 441250.0 113000.0 0.76 373160.0 58800.0 0.43 0.8413 0.9619 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D16 mock treatment 382160.0 54000.0 0.36 376000.0 61700.0 0.45 0.5735 0.995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D17 compound treatment 305390.0 -22800.0 -0.15 294300.0 -20000.0 -0.15 -0.2115 -0.9996 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D18 compound treatment 330600.0 2430.0 0.02 338510.0 24200.0 0.17 0.1353 0.77 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D19 compound treatment 269970.0 -58200.0 -0.39 319920.0 5580.0 0.04 -0.2496 -0.6312 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D20 compound treatment 295470.0 -32700.0 -0.22 312800.0 -1540.0 -0.01 -0.1642 -0.7419 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D21 compound treatment 305410.0 -22800.0 -0.15 353520.0 39200.0 0.28 0.0918 0.2844 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D22 compound treatment 268710.0 -59500.0 -0.4 340750.0 26400.0 0.19 -0.149 -0.3348 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D23 compound treatment 284610.0 -43600.0 -0.29 355720.0 41400.0 0.3 0.0036 0.0087 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 D24 compound treatment 113710.0 -214000.0 -1.45 170180.0 -144000.0 -1.04 -1.7626 -0.987 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E01 mock treatment 372240.0 44100.0 0.3 379320.0 65000.0 0.47 0.5431 0.9757 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E02 mock treatment 251740.0 -76400.0 -0.52 412260.0 97900.0 0.71 0.136 0.1551 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E03 compound treatment 101200.0 -227000.0 -1.53 111890.0 -202000.0 -1.47 -2.1207 -0.9997 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E04 compound treatment 139040.0 -189000.0 -1.28 131270.0 -183000.0 -1.33 -1.8408 -0.9998 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E05 compound treatment 282170.0 -46000.0 -0.31 236820.0 -77500.0 -0.56 -0.6166 -0.9612 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E06 compound treatment 337800.0 9630.0 0.07 255750.0 -58600.0 -0.42 -0.2539 -0.5918 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E07 compound treatment 232080.0 -96100.0 -0.65 278600.0 -35700.0 -0.26 -0.6421 -0.9186 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E08 compound treatment 325860.0 -2310.0 -0.02 317670.0 3330.0 0.02 0.006 0.2076 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E09 mock treatment 320220.0 -7950.0 -0.05 275080.0 -39300.0 -0.28 -0.239 -0.8262 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E10 mock treatment 360220.0 32000.0 0.22 404960.0 90600.0 0.66 0.6169 0.8931 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E11 compound treatment 163590.0 -165000.0 -1.11 159520.0 -155000.0 -1.12 -1.5789 -1.0 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E12 compound treatment 368480.0 40300.0 0.27 323890.0 9550.0 0.07 0.2414 0.8593 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E13 compound treatment 156640.0 -172000.0 -1.16 170480.0 -144000.0 -1.04 -1.556 -0.9986 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E14 compound treatment 359410.0 31200.0 0.21 381120.0 66800.0 0.48 0.491 0.931 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E15 compound treatment 320160.0 -8010.0 -0.05 340800.0 26500.0 0.19 0.0971 0.488 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E16 compound treatment 333180.0 5010.0 0.03 383000.0 68700.0 0.5 0.3753 0.7535 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E17 mock treatment 355260.0 27100.0 0.18 295770.0 -18600.0 -0.13 0.0343 0.1512 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E18 mock treatment 307200.0 -21000.0 -0.14 343530.0 29200.0 0.21 0.0492 0.1933 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E19 compound treatment 180450.0 -148000.0 -1.0 180660.0 -134000.0 -0.97 -1.3901 -0.9999 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E20 compound treatment 290430.0 -37700.0 -0.26 302000.0 -12300.0 -0.09 -0.2435 -0.9012 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E21 compound treatment 134400.0 -194000.0 -1.31 110140.0 -204000.0 -1.48 -1.9711 -0.9982 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E22 compound treatment 153600.0 -175000.0 -1.18 139420.0 -175000.0 -1.27 -1.7295 -0.9994 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E23 compound treatment 147520.0 -181000.0 -1.22 128900.0 -185000.0 -1.34 -1.8124 -0.9989 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 E24 compound treatment 137840.0 -190000.0 -1.29 116570.0 -198000.0 -1.43 -1.9217 -0.9986 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F01 mock treatment 422310.0 94100.0 0.64 322940.0 8600.0 0.06 0.4938 0.7726 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F02 mock treatment 292320.0 -35900.0 -0.24 290720.0 -23600.0 -0.17 -0.2922 -0.9855 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F03 compound treatment 257870.0 -70300.0 -0.48 277880.0 -36500.0 -0.26 -0.5226 -0.9615 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F04 compound treatment 398300.0 70100.0 0.47 272260.0 -42100.0 -0.3 0.1196 0.2124 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F05 compound treatment 247200.0 -81000.0 -0.55 286180.0 -28200.0 -0.2 -0.531 -0.9095 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F06 compound treatment 219450.0 -109000.0 -0.73 212320.0 -102000.0 -0.74 -1.0417 -1.0 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F07 compound treatment 415200.0 87000.0 0.59 300080.0 -14300.0 -0.1 0.3428 0.5741 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F08 compound treatment 238560.0 -89600.0 -0.61 229280.0 -85100.0 -0.62 -0.8636 -1.0 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F09 mock treatment 273190.0 -55000.0 -0.37 245380.0 -69000.0 -0.5 -0.6157 -0.9894 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F10 mock treatment 440360.0 112000.0 0.76 340850.0 26500.0 0.19 0.6717 0.859 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F11 compound treatment 283630.0 -44500.0 -0.3 388590.0 74200.0 0.54 0.1672 0.2715 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F12 compound treatment 221400.0 -107000.0 -0.72 284560.0 -29800.0 -0.22 -0.6626 -0.88 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F13 compound treatment 392720.0 64500.0 0.44 371900.0 57600.0 0.42 0.603 0.9997 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F14 compound treatment 370590.0 42400.0 0.29 354500.0 40200.0 0.29 0.4082 1.0 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F15 compound treatment 209280.0 -119000.0 -0.8 181470.0 -133000.0 -0.96 -1.2482 -0.996 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F16 compound treatment 309640.0 -18500.0 -0.13 248840.0 -65500.0 -0.47 -0.4239 -0.8642 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F17 mock treatment 378280.0 50100.0 0.34 387000.0 72700.0 0.53 0.6113 0.9773 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F18 mock treatment 285140.0 -43000.0 -0.29 327680.0 13300.0 0.1 -0.1374 -0.4483 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F19 compound treatment 197380.0 -131000.0 -0.88 161760.0 -153000.0 -1.1 -1.4059 -0.9939 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F20 compound treatment 264400.0 -63800.0 -0.43 291330.0 -23000.0 -0.17 -0.4225 -0.9145 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F21 compound treatment 214190.0 -114000.0 -0.77 227640.0 -86700.0 -0.63 -0.9884 -0.9948 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F22 compound treatment 333770.0 5600.0 0.04 304770.0 -9570.0 -0.07 -0.0223 -0.2822 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F23 compound treatment 273440.0 -54700.0 -0.37 396960.0 82600.0 0.6 0.1614 0.2295 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 F24 compound treatment 261070.0 -67100.0 -0.45 307320.0 -7020.0 -0.05 -0.3566 -0.7815 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G01 compound treatment 190770.0 -137000.0 -0.93 333820.0 19500.0 0.14 -0.5568 -0.5929 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G02 compound treatment 267650.0 -60500.0 -0.41 408130.0 93800.0 0.68 0.1909 0.2408 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G03 mock treatment 394400.0 66200.0 0.45 311570.0 -2770.0 -0.02 0.3022 0.6747 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G04 mock treatment 283000.0 -45200.0 -0.31 321370.0 7030.0 0.05 -0.1799 -0.5813 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G05 compound treatment 107360.0 -221000.0 -1.49 154560.0 -160000.0 -1.16 -1.8729 -0.9921 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G06 compound treatment 142980.0 -185000.0 -1.25 167260.0 -147000.0 -1.06 -1.6377 -0.9968 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G07 compound treatment 133830.0 -194000.0 -1.31 149710.0 -165000.0 -1.19 -1.7713 -0.9988 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G08 compound treatment 156550.0 -172000.0 -1.16 177980.0 -136000.0 -0.99 -1.518 -0.9968 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G09 compound treatment 411150.0 83000.0 0.56 391520.0 77200.0 0.56 0.7915 1.0 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G10 compound treatment 424800.0 96600.0 0.65 447750.0 133000.0 0.97 1.1445 0.9818 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G11 compound treatment 142140.0 -186000.0 -1.26 161290.0 -153000.0 -1.11 -1.6723 -0.998 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G12 compound treatment 274490.0 -53700.0 -0.36 303840.0 -10500.0 -0.08 -0.3103 -0.8371 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G13 compound treatment 386400.0 58200.0 0.39 387930.0 73600.0 0.53 0.6548 0.9889 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G14 compound treatment 336000.0 7830.0 0.05 347310.0 33000.0 0.24 0.2061 0.8433 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G15 compound treatment 349730.0 21600.0 0.15 345860.0 31500.0 0.23 0.2643 0.9765 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G16 compound treatment 159480.0 -169000.0 -1.14 167850.0 -146000.0 -1.06 -1.5559 -0.9993 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G17 compound treatment 318900.0 -9270.0 -0.06 303590.0 -10800.0 -0.08 -0.0994 -0.9942 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G18 compound treatment 172160.0 -156000.0 -1.05 165010.0 -149000.0 -1.08 -1.5098 -0.9999 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G19 mock treatment 338010.0 9840.0 0.07 454720.0 140000.0 1.02 0.7655 0.7517 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G20 mock treatment 301000.0 -27200.0 -0.18 344400.0 30100.0 0.22 0.024 0.0843 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G21 compound treatment 156720.0 -171000.0 -1.16 163530.0 -151000.0 -1.09 -1.5912 -0.9996 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G22 compound treatment 294190.0 -34000.0 -0.23 332590.0 18200.0 0.13 -0.069 -0.2604 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G23 compound treatment 269220.0 -59000.0 -0.4 258950.0 -55400.0 -0.4 -0.5652 -1.0 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 G24 compound treatment 234790.0 -93400.0 -0.63 330140.0 15800.0 0.11 -0.3653 -0.5697 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H01 compound treatment 286680.0 -41500.0 -0.28 263210.0 -51100.0 -0.37 -0.46 -0.9906 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H02 compound treatment 208430.0 -120000.0 -0.81 282470.0 -31900.0 -0.23 -0.7353 -0.8739 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H03 mock treatment 296960.0 -31200.0 -0.21 229280.0 -85100.0 -0.62 -0.5846 -0.8981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H04 mock treatment 221330.0 -107000.0 -0.72 419700.0 105000.0 0.76 0.0288 0.0274 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H05 compound treatment 284670.0 -43500.0 -0.29 283170.0 -31200.0 -0.23 -0.3674 -0.9915 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H06 compound treatment 279200.0 -49000.0 -0.33 217280.0 -97100.0 -0.7 -0.7308 -0.941 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H07 compound treatment 256660.0 -71500.0 -0.48 304530.0 -9810.0 -0.07 -0.3919 -0.8024 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H08 compound treatment 394080.0 65900.0 0.45 341400.0 27100.0 0.2 0.4534 0.9319 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H09 compound treatment 200160.0 -128000.0 -0.86 205150.0 -109000.0 -0.79 -1.1706 -0.999 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H10 compound treatment 243140.0 -85000.0 -0.57 208040.0 -106000.0 -0.77 -0.9504 -0.9896 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H11 compound treatment 319010.0 -9160.0 -0.06 244260.0 -70100.0 -0.51 -0.4025 -0.7876 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H12 compound treatment 273760.0 -54400.0 -0.37 202400.0 -112000.0 -0.81 -0.833 -0.9361 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H13 compound treatment 305990.0 -22200.0 -0.15 383460.0 69100.0 0.5 0.2478 0.4744 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H14 compound treatment 205010.0 -123000.0 -0.83 306450.0 -7890.0 -0.06 -0.6289 -0.7539 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H15 compound treatment 358660.0 30500.0 0.21 357760.0 43400.0 0.31 0.3679 0.979 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H16 compound treatment 275790.0 -52400.0 -0.35 266720.0 -47600.0 -0.34 -0.4941 -0.9999 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H17 compound treatment 332330.0 4160.0 0.03 283040.0 -31300.0 -0.23 -0.1404 -0.6148 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H18 compound treatment 357280.0 29100.0 0.2 264190.0 -50200.0 -0.36 -0.1177 -0.285 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H19 mock treatment 413410.0 85200.0 0.58 318900.0 4560.0 0.03 0.4306 0.7464 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H20 mock treatment 419710.0 91500.0 0.62 385770.0 71400.0 0.52 0.8029 0.996 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H21 compound treatment 203010.0 -125000.0 -0.85 118990.0 -195000.0 -1.41 -1.598 -0.9698 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H22 compound treatment 297930.0 -30200.0 -0.2 419610.0 105000.0 0.76 0.3943 0.4998 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H23 compound treatment 285290.0 -42900.0 -0.29 429720.0 115000.0 0.84 0.3857 0.4363 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 H24 compound treatment 291520.0 -36700.0 -0.25 302150.0 -12200.0 -0.09 -0.2376 -0.9035 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I01 compound treatment 168430.0 -160000.0 -1.08 171170.0 -143000.0 -1.04 -1.4961 -0.9998 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I02 compound treatment 288900.0 -39300.0 -0.27 252830.0 -61500.0 -0.45 -0.5025 -0.9694 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I03 compound treatment 273620.0 -54600.0 -0.37 170510.0 -144000.0 -1.04 -0.9969 -0.9026 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I04 compound treatment 140860.0 -187000.0 -1.27 129700.0 -185000.0 -1.34 -1.8401 -0.9996 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I05 mock treatment 323890.0 -4280.0 -0.03 207570.0 -107000.0 -0.77 -0.567 -0.7331 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I06 mock treatment 405820.0 77600.0 0.52 199040.0 -115000.0 -0.83 -0.2192 -0.2224 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I07 compound treatment 420680.0 92500.0 0.63 398720.0 84400.0 0.61 0.8739 0.9999 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I08 compound treatment 226530.0 -102000.0 -0.69 195360.0 -119000.0 -0.86 -1.0947 -0.9937 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I09 compound treatment 326920.0 -1250.0 -0.01 293120.0 -21200.0 -0.15 -0.1146 -0.745 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I10 compound treatment 170650.0 -158000.0 -1.06 181370.0 -133000.0 -0.96 -1.4333 -0.9987 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I11 compound treatment 439650.0 111000.0 0.75 207200.0 -107000.0 -0.78 -0.0158 -0.0146 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I12 compound treatment 268260.0 -59900.0 -0.4 193120.0 -121000.0 -0.88 -0.9068 -0.9383 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I13 compound treatment 242610.0 -85600.0 -0.58 344000.0 29700.0 0.21 -0.257 -0.4167 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I14 compound treatment 190570.0 -138000.0 -0.93 181020.0 -133000.0 -0.97 -1.3399 -0.9998 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I15 compound treatment 425130.0 97000.0 0.66 287680.0 -26700.0 -0.19 0.3267 0.4784 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I16 compound treatment 350330.0 22200.0 0.15 391320.0 77000.0 0.56 0.4999 0.8664 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I17 compound treatment 364160.0 36000.0 0.24 325930.0 11600.0 0.08 0.2312 0.899 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I18 compound treatment 331590.0 3420.0 0.02 395120.0 80800.0 0.58 0.4298 0.7344 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I19 compound treatment 165920.0 -162000.0 -1.1 195550.0 -119000.0 -0.86 -1.3833 -0.9928 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I20 compound treatment 155760.0 -172000.0 -1.16 164250.0 -150000.0 -1.09 -1.5921 -0.9994 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I21 mock treatment 329600.0 1430.0 0.01 347550.0 33200.0 0.24 0.1768 0.7348 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I22 mock treatment 288000.0 -40200.0 -0.27 315840.0 1500.0 0.01 -0.1843 -0.6784 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I23 compound treatment 304840.0 -23300.0 -0.16 366590.0 52200.0 0.38 0.1559 0.3806 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 I24 compound treatment 276610.0 -51600.0 -0.35 258190.0 -56200.0 -0.41 -0.5338 -0.9971 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J01 compound treatment 9600.0 -319000.0 -2.15 11580.0 -303000.0 -2.19 -3.0718 -1.0 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J02 compound treatment 212120.0 -116000.0 -0.78 267220.0 -47100.0 -0.34 -0.7957 -0.9305 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J03 compound treatment 383040.0 54900.0 0.37 343400.0 29100.0 0.21 0.4109 0.964 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J04 compound treatment 228600.0 -99600.0 -0.67 163260.0 -151000.0 -1.09 -1.2491 -0.9728 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J05 mock treatment 186460.0 -142000.0 -0.96 327520.0 13200.0 0.1 -0.6096 -0.6335 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J06 mock treatment 379860.0 51700.0 0.35 210760.0 -104000.0 -0.75 -0.2833 -0.3425 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J07 compound treatment 407700.0 79500.0 0.54 257940.0 -56400.0 -0.41 0.0912 0.1352 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J08 compound treatment 135440.0 -193000.0 -1.3 261600.0 -52700.0 -0.38 -1.1908 -0.8775 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J09 compound treatment 211050.0 -117000.0 -0.79 224760.0 -89600.0 -0.65 -1.0182 -0.9951 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J10 compound treatment 239300.0 -88900.0 -0.6 215930.0 -98400.0 -0.71 -0.9284 -0.9964 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J11 compound treatment 442580.0 114000.0 0.77 209630.0 -105000.0 -0.76 0.0106 0.0098 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J12 compound treatment 282880.0 -45300.0 -0.31 188810.0 -126000.0 -0.91 -0.859 -0.8958 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J13 compound treatment 281490.0 -46700.0 -0.32 340700.0 26400.0 0.19 -0.0881 -0.2391 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J14 compound treatment 334880.0 6710.0 0.05 299810.0 -14500.0 -0.11 -0.0424 -0.3698 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J15 compound treatment 382810.0 54600.0 0.37 279080.0 -35300.0 -0.26 0.0805 0.1794 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J16 compound treatment 213330.0 -115000.0 -0.78 328830.0 14500.0 0.1 -0.4746 -0.606 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J17 compound treatment 239870.0 -88300.0 -0.6 419540.0 105000.0 0.76 0.1166 0.1205 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J18 compound treatment 406610.0 78400.0 0.53 314490.0 145.0 0.0 0.3755 0.7085 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J19 compound treatment 261620.0 -66600.0 -0.45 384530.0 70200.0 0.51 0.0413 0.0608 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J20 compound treatment 212160.0 -116000.0 -0.78 202490.0 -112000.0 -0.81 -1.1268 -0.9999 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J21 mock treatment 319140.0 -9030.0 -0.06 422720.0 108000.0 0.78 0.5116 0.6501 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J22 mock treatment 282450.0 -45700.0 -0.31 370830.0 56500.0 0.41 0.0707 0.1379 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J23 compound treatment 277280.0 -50900.0 -0.34 359730.0 45400.0 0.33 -0.0109 -0.0228 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 J24 compound treatment 209560.0 -119000.0 -0.8 251040.0 -63300.0 -0.46 -0.8908 -0.9648 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K01 compound treatment 416320.0 88100.0 0.6 176830.0 -138000.0 -1.0 -0.2828 -0.2438 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K02 compound treatment 278560.0 -49600.0 -0.34 181280.0 -133000.0 -0.96 -0.9182 -0.9002 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K03 compound treatment 174560.0 -154000.0 -1.04 330730.0 16400.0 0.12 -0.6501 -0.6223 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K04 compound treatment 206990.0 -121000.0 -0.82 422400.0 108000.0 0.78 -0.0259 -0.0229 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K05 compound treatment 380060.0 51900.0 0.35 210020.0 -104000.0 -0.76 -0.2861 -0.3436 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K06 compound treatment 392390.0 64200.0 0.43 259400.0 -54900.0 -0.4 0.0256 0.0434 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K07 mock treatment 446720.0 119000.0 0.8 242510.0 -71800.0 -0.52 0.1987 0.2081 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K08 mock treatment 268750.0 -59400.0 -0.4 203400.0 -111000.0 -0.8 -0.8518 -0.9487 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K09 compound treatment 257440.0 -70700.0 -0.48 318900.0 4560.0 0.03 -0.3146 -0.6568 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K10 compound treatment 348570.0 20400.0 0.14 347450.0 33100.0 0.24 0.2669 0.9655 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K11 compound treatment 364320.0 36100.0 0.24 246930.0 -67400.0 -0.49 -0.1724 -0.3159 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K12 compound treatment 340910.0 12700.0 0.09 297780.0 -16600.0 -0.12 -0.0239 -0.1622 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K13 compound treatment 253360.0 -74800.0 -0.51 285290.0 -29100.0 -0.21 -0.5062 -0.9245 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K14 compound treatment 392020.0 63800.0 0.43 494480.0 180000.0 1.3 1.2271 0.8934 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K15 mock treatment 276750.0 -51400.0 -0.35 279730.0 -34600.0 -0.25 -0.4229 -0.9871 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K16 mock treatment 333670.0 5500.0 0.04 359720.0 45400.0 0.33 0.2585 0.7821 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K17 compound treatment 415120.0 86900.0 0.59 412570.0 98200.0 0.71 0.9182 0.9955 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K18 compound treatment 535750.0 208000.0 1.4 441870.0 128000.0 0.92 1.6445 0.9794 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K19 compound treatment 176480.0 -152000.0 -1.02 156200.0 -158000.0 -1.14 -1.5343 -0.9985 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K20 compound treatment 450880.0 123000.0 0.83 384670.0 70300.0 0.51 0.9462 0.9726 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K21 compound treatment 300860.0 -27300.0 -0.18 284170.0 -30200.0 -0.22 -0.285 -0.9965 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K22 compound treatment 362920.0 34700.0 0.23 319680.0 5340.0 0.04 0.1933 0.8125 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K23 mock treatment 388670.0 60500.0 0.41 313760.0 -585.0 0.0 0.286 0.6997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 K24 mock treatment 317760.0 -10400.0 -0.07 344890.0 30500.0 0.22 0.1066 0.4594 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L01 compound treatment 299710.0 -28500.0 -0.19 408710.0 94400.0 0.68 0.347 0.489 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L02 compound treatment 264230.0 -63900.0 -0.43 248290.0 -66100.0 -0.48 -0.6436 -0.9987 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L03 compound treatment 192160.0 -136000.0 -0.92 352320.0 38000.0 0.27 -0.4555 -0.4748 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L04 compound treatment 221600.0 -107000.0 -0.72 186630.0 -128000.0 -0.92 -1.1629 -0.9924 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L05 compound treatment 349880.0 21700.0 0.15 167810.0 -147000.0 -1.06 -0.6464 -0.6036 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L06 compound treatment 257360.0 -70800.0 -0.48 192870.0 -121000.0 -0.88 -0.9601 -0.9591 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L07 mock treatment 203810.0 -124000.0 -0.84 215520.0 -98800.0 -0.72 -1.1 -0.9968 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L08 mock treatment 232020.0 -96200.0 -0.65 221600.0 -92700.0 -0.67 -0.9341 -0.9999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L09 compound treatment 299840.0 -28300.0 -0.19 372100.0 57800.0 0.42 0.1603 0.3485 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L10 compound treatment 266520.0 -61700.0 -0.42 184130.0 -130000.0 -0.94 -0.9611 -0.9326 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L11 compound treatment 206720.0 -121000.0 -0.82 262530.0 -51800.0 -0.38 -0.8455 -0.9371 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L12 compound treatment 370030.0 41900.0 0.28 340030.0 25700.0 0.19 0.3315 0.9793 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L13 compound treatment 351320.0 23100.0 0.16 271930.0 -42400.0 -0.31 -0.1065 -0.3092 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L14 compound treatment 253830.0 -74300.0 -0.5 239650.0 -74700.0 -0.54 -0.7375 -0.9993 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L15 mock treatment 423280.0 95100.0 0.64 243250.0 -71100.0 -0.51 0.0905 0.1099 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L16 mock treatment 406500.0 78300.0 0.53 241130.0 -73200.0 -0.53 -5.0E-4 -7.0E-4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L17 compound treatment 103550.0 -225000.0 -1.52 91130.0 -223000.0 -1.62 -2.2158 -0.9995 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L18 compound treatment 425220.0 97000.0 0.66 202630.0 -112000.0 -0.81 -0.1082 -0.1039 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L19 compound treatment 225570.0 -103000.0 -0.69 227710.0 -86600.0 -0.63 -0.9337 -0.9987 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L20 compound treatment 271840.0 -56300.0 -0.38 263520.0 -50800.0 -0.37 -0.5293 -0.9999 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L21 compound treatment 218620.0 -110000.0 -0.74 276520.0 -37800.0 -0.27 -0.717 -0.9085 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L22 compound treatment 240160.0 -88000.0 -0.59 395580.0 81200.0 0.59 -0.0047 -0.0056 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L23 mock treatment 336160.0 7990.0 0.05 427550.0 113000.0 0.82 0.6176 0.752 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 L24 mock treatment 440340.0 112000.0 0.76 442340.0 128000.0 0.93 1.1911 0.995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M01 compound treatment 169550.0 -159000.0 -1.07 383050.0 68700.0 0.5 -0.4062 -0.3438 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M02 compound treatment 152810.0 -175000.0 -1.18 368480.0 54100.0 0.39 -0.5608 -0.4493 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M03 compound treatment 357690.0 29500.0 0.2 216670.0 -97700.0 -0.71 -0.359 -0.4886 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M04 compound treatment 120900.0 -207000.0 -1.4 149650.0 -165000.0 -1.19 -1.8333 -0.9968 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M05 compound treatment 184590.0 -144000.0 -0.97 175410.0 -139000.0 -1.01 -1.3972 -0.9998 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M06 compound treatment 207320.0 -121000.0 -0.82 376230.0 61900.0 0.45 -0.2606 -0.2798 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M07 compound treatment 199240.0 -129000.0 -0.87 120050.0 -194000.0 -1.41 -1.6106 -0.9735 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M08 compound treatment 183840.0 -144000.0 -0.98 140000.0 -174000.0 -1.26 -1.582 -0.9919 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M09 mock treatment 265000.0 -63200.0 -0.43 159810.0 -155000.0 -1.12 -1.0929 -0.9127 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M10 mock treatment 352640.0 24500.0 0.17 432640.0 118000.0 0.86 0.7224 0.8283 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M11 compound treatment 220280.0 -108000.0 -0.73 216500.0 -97800.0 -0.71 -1.0163 -0.9999 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M12 compound treatment 211090.0 -117000.0 -0.79 289770.0 -24600.0 -0.18 -0.6852 -0.845 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M13 mock treatment 387880.0 59700.0 0.4 309400.0 -4940.0 -0.04 0.2599 0.6418 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M14 mock treatment 385530.0 57400.0 0.39 424040.0 110000.0 0.79 0.8355 0.9456 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M15 compound treatment 497600.0 169000.0 1.14 384860.0 70500.0 0.51 1.1704 0.9338 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M16 compound treatment 233730.0 -94400.0 -0.64 252420.0 -61900.0 -0.45 -0.7682 -0.9851 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M17 compound treatment 342410.0 14200.0 0.1 371750.0 57400.0 0.42 0.3619 0.8483 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M18 compound treatment 273810.0 -54400.0 -0.37 320660.0 6320.0 0.05 -0.2274 -0.6144 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M19 compound treatment 180640.0 -148000.0 -1.0 172060.0 -142000.0 -1.03 -1.4332 -0.9999 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M20 compound treatment 266960.0 -61200.0 -0.41 336350.0 22000.0 0.16 -0.1798 -0.4057 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M21 compound treatment 194570.0 -134000.0 -0.9 282130.0 -32200.0 -0.23 -0.8032 -0.8615 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M22 compound treatment 157920.0 -170000.0 -1.15 140660.0 -174000.0 -1.26 -1.7025 -0.999 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M23 compound treatment 133730.0 -194000.0 -1.31 190660.0 -124000.0 -0.9 -1.5621 -0.9825 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 M24 compound treatment 187640.0 -141000.0 -0.95 188420.0 -126000.0 -0.91 -1.316 -0.9998 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N01 compound treatment 313340.0 -14800.0 -0.1 370720.0 56400.0 0.41 0.2177 0.518 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N02 compound treatment 141250.0 -187000.0 -1.26 328110.0 13800.0 0.1 -0.8226 -0.6493 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N03 compound treatment 121030.0 -207000.0 -1.4 172320.0 -142000.0 -1.03 -1.7167 -0.9885 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N04 compound treatment 223140.0 -105000.0 -0.71 203760.0 -111000.0 -0.8 -1.0679 -0.9982 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N05 compound treatment 246420.0 -81800.0 -0.55 212720.0 -102000.0 -0.74 -0.9108 -0.99 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N06 compound treatment 233000.0 -95200.0 -0.64 253490.0 -60900.0 -0.44 -0.7662 -0.983 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N07 compound treatment 323800.0 -4370.0 -0.03 204170.0 -110000.0 -0.8 -0.5849 -0.7328 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N08 compound treatment 292380.0 -35800.0 -0.24 227720.0 -86600.0 -0.63 -0.6144 -0.9142 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N09 mock treatment 413440.0 85300.0 0.58 321350.0 7010.0 0.05 0.4432 0.7664 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N10 mock treatment 298590.0 -29600.0 -0.2 290890.0 -23500.0 -0.17 -0.2614 -0.9967 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N11 compound treatment 285360.0 -42800.0 -0.29 363280.0 48900.0 0.35 0.0459 0.1004 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N12 compound treatment 170190.0 -158000.0 -1.07 375080.0 60700.0 0.44 -0.4439 -0.3845 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N13 mock treatment 319560.0 -8610.0 -0.06 301410.0 -12900.0 -0.09 -0.1074 -0.9738 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N14 mock treatment 357600.0 29400.0 0.2 311330.0 -3010.0 -0.02 0.1252 0.6257 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N15 compound treatment 272240.0 -55900.0 -0.38 206570.0 -108000.0 -0.78 -0.8189 -0.9446 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N16 compound treatment 270570.0 -57600.0 -0.39 224920.0 -89400.0 -0.65 -0.733 -0.9704 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N17 compound treatment 209720.0 -118000.0 -0.8 281510.0 -32800.0 -0.24 -0.734 -0.8791 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N18 compound treatment 412720.0 84500.0 0.57 246960.0 -67400.0 -0.49 0.059 0.0786 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N19 compound treatment 249070.0 -79100.0 -0.53 302470.0 -11900.0 -0.09 -0.4387 -0.8104 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N20 compound treatment 131120.0 -197000.0 -1.33 146630.0 -168000.0 -1.21 -1.8 -0.9989 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N21 compound treatment 139040.0 -189000.0 -1.28 159100.0 -155000.0 -1.12 -1.6983 -0.9979 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N22 compound treatment 228160.0 -100000.0 -0.68 346300.0 32000.0 0.23 -0.3143 -0.44 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N23 compound treatment 203450.0 -125000.0 -0.84 239520.0 -74800.0 -0.54 -0.9789 -0.9772 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 N24 compound treatment 273770.0 -54400.0 -0.37 341220.0 26900.0 0.19 -0.1224 -0.2942 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O01 compound treatment 217170.0 -111000.0 -0.75 286400.0 -27900.0 -0.2 -0.6734 -0.8668 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O02 compound treatment 224600.0 -104000.0 -0.7 340580.0 26200.0 0.19 -0.3606 -0.4972 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O03 compound treatment 80260.0 -248000.0 -1.68 119520.0 -195000.0 -1.41 -2.1817 -0.9963 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O04 compound treatment 266460.0 -61700.0 -0.42 249920.0 -64400.0 -0.47 -0.6246 -0.9984 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O05 compound treatment 127410.0 -201000.0 -1.36 158720.0 -156000.0 -1.13 -1.7558 -0.9957 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O06 compound treatment 242090.0 -86100.0 -0.58 248410.0 -65900.0 -0.48 -0.7488 -0.9952 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O07 compound treatment 112990.0 -215000.0 -1.45 141120.0 -173000.0 -1.25 -1.9148 -0.9973 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O08 compound treatment 117400.0 -211000.0 -1.42 127480.0 -187000.0 -1.35 -1.9635 -0.9997 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O09 compound treatment 233820.0 -94400.0 -0.64 352690.0 38300.0 0.28 -0.2545 -0.366 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O10 compound treatment 270320.0 -57900.0 -0.39 239150.0 -75200.0 -0.54 -0.6613 -0.9868 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O11 mock treatment 321540.0 -6630.0 -0.04 245460.0 -68900.0 -0.5 -0.3843 -0.7676 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O12 mock treatment 297400.0 -30800.0 -0.21 236960.0 -77400.0 -0.56 -0.5431 -0.909 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O13 compound treatment 333550.0 5380.0 0.04 258510.0 -55800.0 -0.4 -0.2601 -0.641 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O14 compound treatment 297880.0 -30300.0 -0.2 262720.0 -51600.0 -0.37 -0.409 -0.9599 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O15 compound treatment 313800.0 -14400.0 -0.1 278320.0 -36000.0 -0.26 -0.2531 -0.9094 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O16 compound treatment 317330.0 -10800.0 -0.07 270270.0 -44100.0 -0.32 -0.2774 -0.8474 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O17 compound treatment 114830.0 -213000.0 -1.44 118620.0 -196000.0 -1.42 -2.0212 -1.0 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O18 compound treatment 163960.0 -164000.0 -1.11 182760.0 -132000.0 -0.95 -1.4581 -0.9971 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O19 compound treatment 146880.0 -181000.0 -1.22 160340.0 -154000.0 -1.11 -1.6545 -0.9989 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O20 compound treatment 285600.0 -42600.0 -0.29 325280.0 10900.0 0.08 -0.1474 -0.4942 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O21 compound treatment 187090.0 -141000.0 -0.95 234910.0 -79400.0 -0.58 -1.0807 -0.9707 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O22 compound treatment 230160.0 -98000.0 -0.66 269160.0 -45200.0 -0.33 -0.6996 -0.9471 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O23 compound treatment 240320.0 -87900.0 -0.59 223520.0 -90800.0 -0.66 -0.8847 -0.9987 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 O24 compound treatment 223630.0 -105000.0 -0.71 287840.0 -26500.0 -0.19 -0.6352 -0.8677 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P01 compound treatment 306080.0 -22100.0 -0.15 301770.0 -12600.0 -0.09 -0.1699 -0.9718 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P02 compound treatment 165460.0 -163000.0 -1.1 213680.0 -101000.0 -0.73 -1.2927 -0.9801 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P03 compound treatment 205730.0 -122000.0 -0.83 269790.0 -44600.0 -0.32 -0.8131 -0.9156 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P04 compound treatment 230180.0 -98000.0 -0.66 216500.0 -97800.0 -0.71 -0.969 -0.9994 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P05 compound treatment 245250.0 -82900.0 -0.56 215920.0 -98400.0 -0.71 -0.9 -0.9929 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P06 compound treatment 176210.0 -152000.0 -1.03 187210.0 -127000.0 -0.92 -1.3768 -0.9985 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P07 compound treatment 152640.0 -176000.0 -1.19 159920.0 -154000.0 -1.12 -1.6291 -0.9996 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P08 compound treatment 257380.0 -70800.0 -0.48 175250.0 -139000.0 -1.01 -1.0502 -0.9421 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P09 compound treatment 171240.0 -157000.0 -1.06 158440.0 -156000.0 -1.13 -1.5478 -0.9995 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P10 compound treatment 188240.0 -140000.0 -0.95 224020.0 -90300.0 -0.65 -1.1309 -0.9838 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P11 mock treatment 192480.0 -136000.0 -0.92 224540.0 -89800.0 -0.65 -1.108 -0.9858 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P12 mock treatment 197390.0 -131000.0 -0.88 241480.0 -72900.0 -0.53 -0.9978 -0.9696 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P13 compound treatment 96520.0 -232000.0 -1.57 74630.0 -240000.0 -1.74 -2.3338 -0.9987 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P14 compound treatment 217000.0 -111000.0 -0.75 185780.0 -129000.0 -0.93 -1.1893 -0.9944 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P15 compound treatment 178280.0 -150000.0 -1.01 159220.0 -155000.0 -1.12 -1.5102 -0.9987 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P16 compound treatment 184390.0 -144000.0 -0.97 186410.0 -128000.0 -0.93 -1.3418 -0.9997 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P17 compound treatment 3210.0 -325000.0 -2.2 4320.0 -310000.0 -2.24 -3.1395 -0.9999 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P18 compound treatment 114570.0 -214000.0 -1.44 112960.0 -201000.0 -1.46 -2.0514 -1.0 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P19 compound treatment 2680.0 -325000.0 -2.2 3330.0 -311000.0 -2.25 -3.1471 -0.9999 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P20 compound treatment 192410.0 -136000.0 -0.92 153670.0 -161000.0 -1.16 -1.4711 -0.9931 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P21 compound treatment 231080.0 -97100.0 -0.66 207040.0 -107000.0 -0.78 -1.0132 -0.9965 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P22 compound treatment 157800.0 -170000.0 -1.15 188250.0 -126000.0 -0.91 -1.4595 -0.9934 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P23 compound treatment 123800.0 -204000.0 -1.38 127730.0 -187000.0 -1.35 -1.9317 -0.9999 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2096 P24 compound treatment 161210.0 -167000.0 -1.13 206130.0 -108000.0 -0.78 -1.3516 -0.9841 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A01 compound treatment 322770.0 -33900.0 -0.23 327840.0 32600.0 0.24 0.005 0.0153 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A02 compound treatment 343790.0 -12900.0 -0.09 337700.0 42500.0 0.31 0.1559 0.4881 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A03 compound treatment 257800.0 -98800.0 -0.67 228720.0 -66500.0 -0.48 -0.8127 -0.9871 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A04 compound treatment 250880.0 -106000.0 -0.71 294080.0 -1150.0 -0.01 -0.5112 -0.7153 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A05 compound treatment 343730.0 -12900.0 -0.09 351880.0 56600.0 0.41 0.2282 0.5444 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A06 compound treatment 32740.0 -324000.0 -2.19 15220.0 -280000.0 -2.03 -2.9809 -0.9993 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A07 compound treatment 316220.0 -40400.0 -0.27 214750.0 -80500.0 -0.58 -0.6051 -0.9404 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A08 compound treatment 356110.0 -539.0 0.0 211040.0 -84200.0 -0.61 -0.4335 -0.7113 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A09 compound treatment 253780.0 -103000.0 -0.7 256270.0 -39000.0 -0.28 -0.6909 -0.9211 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A10 compound treatment 222000.0 -135000.0 -0.91 220060.0 -75200.0 -0.54 -1.0281 -0.9698 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A11 compound treatment 305940.0 -50700.0 -0.34 288580.0 -6650.0 -0.05 -0.2763 -0.7987 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A12 compound treatment 223570.0 -133000.0 -0.9 204930.0 -90300.0 -0.65 -1.0981 -0.9877 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A13 mock treatment 280510.0 -76100.0 -0.51 220160.0 -75100.0 -0.54 -0.7481 -0.9996 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A14 mock treatment 292480.0 -64200.0 -0.43 314530.0 19300.0 0.14 -0.2078 -0.4562 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A15 compound treatment 228000.0 -129000.0 -0.87 207380.0 -87900.0 -0.64 -1.0644 -0.9882 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A16 compound treatment 291520.0 -65100.0 -0.44 263750.0 -31500.0 -0.23 -0.4723 -0.9531 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A17 compound treatment 243310.0 -113000.0 -0.77 201380.0 -93900.0 -0.68 -1.0219 -0.9982 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A18 compound treatment 377280.0 20600.0 0.14 226630.0 -68600.0 -0.5 -0.2526 -0.4897 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A19 compound treatment 305080.0 -51600.0 -0.35 240900.0 -54300.0 -0.39 -0.5245 -0.9982 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A20 compound treatment 289920.0 -66700.0 -0.45 271650.0 -23600.0 -0.17 -0.4395 -0.9117 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A21 compound treatment 283710.0 -72900.0 -0.49 282570.0 -12700.0 -0.09 -0.4133 -0.8245 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A22 compound treatment 249650.0 -107000.0 -0.72 251730.0 -43500.0 -0.31 -0.7339 -0.9307 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A23 compound treatment 224280.0 -132000.0 -0.89 211840.0 -83400.0 -0.6 -1.0593 -0.9817 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 A24 compound treatment 273490.0 -83200.0 -0.56 251200.0 -44000.0 -0.32 -0.6227 -0.9639 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B01 compound treatment 358570.0 1920.0 0.01 352560.0 57300.0 0.41 0.3026 0.7289 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B02 compound treatment 286610.0 -70000.0 -0.47 250260.0 -45000.0 -0.33 -0.5648 -0.9833 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B03 compound treatment 345500.0 -11100.0 -0.08 302020.0 6790.0 0.05 -0.0185 -0.206 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B04 compound treatment 376360.0 19700.0 0.13 334990.0 39800.0 0.29 0.2977 0.9387 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B05 compound treatment 399060.0 42400.0 0.29 351930.0 56700.0 0.41 0.4928 0.9846 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B06 compound treatment 290960.0 -65700.0 -0.44 260510.0 -34700.0 -0.25 -0.4916 -0.9637 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B07 compound treatment 134290.0 -222000.0 -1.5 178640.0 -117000.0 -0.84 -1.6592 -0.9628 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B08 compound treatment 326560.0 -30100.0 -0.2 303950.0 8720.0 0.06 -0.0991 -0.4657 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B09 compound treatment 251690.0 -105000.0 -0.71 258130.0 -37100.0 -0.27 -0.6914 -0.9117 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B10 compound treatment 227140.0 -130000.0 -0.88 218440.0 -76800.0 -0.56 -1.0119 -0.976 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B11 compound treatment 357120.0 471.0 0.0 283260.0 -12000.0 -0.09 -0.059 -0.6807 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B12 compound treatment 374370.0 17700.0 0.12 254020.0 -41200.0 -0.3 -0.1263 -0.3928 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B13 mock treatment 373640.0 17000.0 0.11 220960.0 -74300.0 -0.54 -0.299 -0.5439 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B14 mock treatment 315890.0 -40800.0 -0.28 276650.0 -18600.0 -0.13 -0.2899 -0.9457 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B15 compound treatment 289920.0 -66700.0 -0.45 333200.0 38000.0 0.27 -0.1245 -0.2357 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B16 compound treatment 308740.0 -47900.0 -0.32 244810.0 -50400.0 -0.37 -0.487 -0.9982 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B17 compound treatment 355520.0 -1130.0 -0.01 305050.0 9820.0 0.07 0.0449 0.6276 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B18 compound treatment 117960.0 -239000.0 -1.61 74800.0 -220000.0 -1.6 -2.2687 -1.0 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B19 compound treatment 258530.0 -98100.0 -0.66 286020.0 -9210.0 -0.07 -0.516 -0.7743 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B20 compound treatment 285120.0 -71500.0 -0.48 279110.0 -16100.0 -0.12 -0.4243 -0.8533 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B21 compound treatment 338250.0 -18400.0 -0.12 281720.0 -13500.0 -0.1 -0.1571 -0.993 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B22 compound treatment 272400.0 -84200.0 -0.57 356420.0 61200.0 0.44 -0.0893 -0.1238 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B23 compound treatment 272330.0 -84300.0 -0.57 238560.0 -56700.0 -0.41 -0.693 -0.987 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 B24 compound treatment 278130.0 -78500.0 -0.53 262940.0 -32300.0 -0.23 -0.5404 -0.9322 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C01 compound treatment 327870.0 -28800.0 -0.19 247580.0 -47700.0 -0.34 -0.3814 -0.9632 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C02 compound treatment 240360.0 -116000.0 -0.79 238590.0 -56600.0 -0.41 -0.8455 -0.954 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C03 compound treatment 166770.0 -190000.0 -1.28 185960.0 -109000.0 -0.79 -1.4665 -0.973 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C04 compound treatment 188500.0 -168000.0 -1.14 185820.0 -109000.0 -0.79 -1.3634 -0.9844 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C05 compound treatment 268440.0 -88200.0 -0.6 243900.0 -51300.0 -0.37 -0.6842 -0.9741 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C06 compound treatment 295370.0 -61300.0 -0.41 335890.0 40700.0 0.29 -0.0847 -0.1667 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C07 compound treatment 279860.0 -76800.0 -0.52 281800.0 -13400.0 -0.1 -0.4356 -0.8253 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C08 compound treatment 319740.0 -36900.0 -0.25 298180.0 2950.0 0.02 -0.1613 -0.6443 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C09 compound treatment 235700.0 -121000.0 -0.82 187460.0 -108000.0 -0.78 -1.1295 -0.9997 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C10 compound treatment 285020.0 -71600.0 -0.48 250430.0 -44800.0 -0.32 -0.5716 -0.981 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C11 mock treatment 368440.0 11800.0 0.08 255710.0 -39500.0 -0.29 -0.146 -0.4915 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C12 mock treatment 293720.0 -62900.0 -0.43 273400.0 -21800.0 -0.16 -0.4124 -0.9092 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C13 compound treatment 342720.0 -13900.0 -0.09 233840.0 -61400.0 -0.44 -0.3808 -0.8383 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C14 compound treatment 35270.0 -321000.0 -2.17 19600.0 -276000.0 -2.0 -2.9464 -0.9991 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C15 mock treatment 335760.0 -20900.0 -0.14 314920.0 19700.0 0.14 0.001 0.0048 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C16 mock treatment 359360.0 2710.0 0.02 214290.0 -80900.0 -0.59 -0.4014 -0.6847 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C17 compound treatment 322790.0 -33900.0 -0.23 211940.0 -83300.0 -0.6 -0.5881 -0.912 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C18 compound treatment 347680.0 -8970.0 -0.06 225880.0 -69400.0 -0.5 -0.3979 -0.7867 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C19 compound treatment 289040.0 -67600.0 -0.46 274050.0 -21200.0 -0.15 -0.4315 -0.8954 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C20 compound treatment 9920.0 -347000.0 -2.34 8480.0 -287000.0 -2.08 -3.1244 -0.9982 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C21 compound treatment 168480.0 -188000.0 -1.27 108600.0 -187000.0 -1.35 -1.8544 -0.9995 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C22 compound treatment 282320.0 -74300.0 -0.5 261810.0 -33400.0 -0.24 -0.5262 -0.9439 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C23 compound treatment 252820.0 -104000.0 -0.7 216720.0 -78500.0 -0.57 -0.898 -0.9945 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 C24 compound treatment 312030.0 -44600.0 -0.3 219610.0 -75600.0 -0.55 -0.6003 -0.9605 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D01 compound treatment 416820.0 60200.0 0.41 306080.0 10800.0 0.08 0.343 0.8284 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D02 compound treatment 407300.0 50700.0 0.34 246040.0 -49200.0 -0.36 -0.0098 -0.0199 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D03 compound treatment 258250.0 -98400.0 -0.66 283930.0 -11300.0 -0.08 -0.528 -0.7882 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D04 compound treatment 276670.0 -80000.0 -0.54 226490.0 -68700.0 -0.5 -0.734 -0.9992 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D05 compound treatment 290490.0 -66200.0 -0.45 301680.0 6450.0 0.05 -0.2831 -0.6299 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D06 compound treatment 215050.0 -142000.0 -0.96 257440.0 -37800.0 -0.27 -0.87 -0.8743 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D07 compound treatment 285920.0 -70700.0 -0.48 269410.0 -25800.0 -0.19 -0.4701 -0.9161 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D08 compound treatment 197000.0 -160000.0 -1.08 183630.0 -112000.0 -0.81 -1.334 -0.9899 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D09 compound treatment 226740.0 -130000.0 -0.88 261960.0 -33300.0 -0.24 -0.791 -0.869 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D10 compound treatment 242300.0 -114000.0 -0.77 197780.0 -97500.0 -0.71 -1.0452 -0.999 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D11 mock treatment 351920.0 -4730.0 -0.03 228710.0 -66500.0 -0.48 -0.3631 -0.7524 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D12 mock treatment 315360.0 -41300.0 -0.28 328640.0 33400.0 0.24 -0.0263 -0.0712 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D13 compound treatment 355360.0 -1290.0 -0.01 378090.0 82900.0 0.6 0.418 0.6968 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D14 compound treatment 275610.0 -81000.0 -0.55 363520.0 68300.0 0.49 -0.0376 -0.051 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D15 mock treatment 419120.0 62500.0 0.42 312330.0 17100.0 0.12 0.386 0.8775 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D16 mock treatment 331240.0 -25400.0 -0.17 286250.0 -8980.0 -0.07 -0.1674 -0.9117 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D17 compound treatment 329350.0 -27300.0 -0.18 323700.0 28500.0 0.21 0.0153 0.0553 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D18 compound treatment 325630.0 -31000.0 -0.21 132550.0 -163000.0 -1.18 -0.9809 -0.8201 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D19 compound treatment 289930.0 -66700.0 -0.45 243040.0 -52200.0 -0.38 -0.5859 -0.9961 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D20 compound treatment 305290.0 -51400.0 -0.35 323950.0 28700.0 0.21 -0.0984 -0.2432 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D21 compound treatment 224640.0 -132000.0 -0.89 217310.0 -77900.0 -0.56 -1.0296 -0.9756 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D22 compound treatment 200800.0 -156000.0 -1.05 205610.0 -89600.0 -0.65 -1.2034 -0.9729 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D23 compound treatment 264090.0 -92600.0 -0.63 281630.0 -13600.0 -0.1 -0.5119 -0.8085 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 D24 compound treatment 386670.0 30000.0 0.2 279370.0 -15900.0 -0.11 0.0622 0.267 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E01 mock treatment 428000.0 71400.0 0.48 249160.0 -46100.0 -0.33 0.1051 0.1792 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E02 mock treatment 344180.0 -12500.0 -0.08 261200.0 -34000.0 -0.25 -0.2338 -0.8979 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E03 compound treatment 310800.0 -45800.0 -0.31 312400.0 17200.0 0.12 -0.1312 -0.393 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E04 compound treatment 375750.0 19100.0 0.13 340190.0 45000.0 0.33 0.3214 0.918 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E05 compound treatment 319530.0 -37100.0 -0.25 270010.0 -25200.0 -0.18 -0.3065 -0.9878 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E06 compound treatment 204800.0 -152000.0 -1.03 161960.0 -133000.0 -0.96 -1.4077 -0.9995 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E07 compound treatment 257230.0 -99400.0 -0.67 277310.0 -17900.0 -0.13 -0.5667 -0.8284 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E08 compound treatment 390290.0 33600.0 0.23 322760.0 27500.0 0.2 0.3016 0.9978 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E09 mock treatment 309210.0 -47400.0 -0.32 236830.0 -58400.0 -0.42 -0.5256 -0.9907 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E10 mock treatment 446770.0 90100.0 0.61 317040.0 21800.0 0.16 0.5422 0.8619 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E11 compound treatment 420690.0 64000.0 0.43 221290.0 -73900.0 -0.54 -0.0725 -0.1054 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E12 compound treatment 121960.0 -235000.0 -1.59 84830.0 -210000.0 -1.52 -2.1983 -0.9998 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E13 compound treatment 239800.0 -117000.0 -0.79 306980.0 11700.0 0.09 -0.4982 -0.6273 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E14 compound treatment 89090.0 -268000.0 -1.81 37390.0 -258000.0 -1.87 -2.5982 -0.9999 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E15 compound treatment 292740.0 -63900.0 -0.43 179720.0 -116000.0 -0.84 -0.8966 -0.9527 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E16 compound treatment 336920.0 -19700.0 -0.13 275380.0 -19900.0 -0.14 -0.1959 -0.9993 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E17 mock treatment 353630.0 -3020.0 -0.02 256970.0 -38300.0 -0.28 -0.2103 -0.7571 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E18 mock treatment 419300.0 62700.0 0.42 261920.0 -33300.0 -0.24 0.1288 0.2644 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E19 compound treatment 238850.0 -118000.0 -0.8 195970.0 -99300.0 -0.72 -1.0709 -0.9987 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E20 compound treatment 229930.0 -127000.0 -0.86 224480.0 -70800.0 -0.51 -0.9676 -0.9698 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E21 compound treatment 231080.0 -126000.0 -0.85 176990.0 -118000.0 -0.86 -1.2052 -1.0 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E22 compound treatment 276820.0 -79800.0 -0.54 210100.0 -85100.0 -0.62 -0.8172 -0.9978 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E23 compound treatment 272440.0 -84200.0 -0.57 281810.0 -13400.0 -0.1 -0.471 -0.8161 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 E24 compound treatment 265510.0 -91100.0 -0.62 213790.0 -81400.0 -0.59 -0.8523 -0.9998 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F01 mock treatment 385150.0 28500.0 0.19 268400.0 -26800.0 -0.19 -0.0012 -0.0043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F02 mock treatment 265370.0 -91300.0 -0.62 382770.0 87500.0 0.63 0.012 0.0135 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F03 compound treatment 242670.0 -114000.0 -0.77 248200.0 -47000.0 -0.34 -0.7853 -0.9326 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F04 compound treatment 243720.0 -113000.0 -0.76 250470.0 -44800.0 -0.32 -0.7687 -0.9272 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F05 compound treatment 183040.0 -174000.0 -1.17 172660.0 -123000.0 -0.89 -1.4569 -0.9905 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F06 compound treatment 260800.0 -95800.0 -0.65 273550.0 -21700.0 -0.16 -0.5689 -0.8538 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F07 compound treatment 309300.0 -47300.0 -0.32 344320.0 49100.0 0.36 0.025 0.0524 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F08 compound treatment 280340.0 -76300.0 -0.52 316580.0 21300.0 0.15 -0.2553 -0.4743 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F09 mock treatment 300180.0 -56500.0 -0.38 249880.0 -45400.0 -0.33 -0.5019 -0.9972 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F10 mock treatment 382840.0 26200.0 0.18 254080.0 -41200.0 -0.3 -0.0855 -0.2468 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F11 compound treatment 272850.0 -83800.0 -0.57 188060.0 -107000.0 -0.78 -0.949 -0.988 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F12 compound treatment 157450.0 -199000.0 -1.35 97870.0 -197000.0 -1.43 -1.962 -0.9996 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F13 compound treatment 344930.0 -11700.0 -0.08 241600.0 -53600.0 -0.39 -0.3305 -0.8341 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F14 compound treatment 394580.0 37900.0 0.26 323700.0 28500.0 0.21 0.3269 0.9942 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F15 compound treatment 185790.0 -171000.0 -1.15 255420.0 -39800.0 -0.29 -1.0201 -0.8573 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F16 compound treatment 294240.0 -62400.0 -0.42 275070.0 -20200.0 -0.15 -0.4014 -0.8995 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F17 mock treatment 373370.0 16700.0 0.11 207110.0 -88100.0 -0.64 -0.3712 -0.573 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F18 mock treatment 299730.0 -56900.0 -0.38 248920.0 -46300.0 -0.34 -0.509 -0.9977 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F19 compound treatment 354720.0 -1930.0 -0.01 266820.0 -28400.0 -0.21 -0.1547 -0.7504 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F20 compound treatment 252480.0 -104000.0 -0.7 237710.0 -57500.0 -0.42 -0.7921 -0.9686 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F21 compound treatment 291690.0 -65000.0 -0.44 180450.0 -115000.0 -0.83 -0.8979 -0.9555 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F22 compound treatment 322140.0 -34500.0 -0.23 237950.0 -57300.0 -0.41 -0.4581 -0.9629 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F23 compound treatment 325440.0 -31200.0 -0.21 267910.0 -27300.0 -0.2 -0.289 -0.9995 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 F24 compound treatment 224160.0 -132000.0 -0.9 158470.0 -137000.0 -0.99 -1.3331 -0.9987 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G01 compound treatment 384860.0 28200.0 0.19 367680.0 72400.0 0.52 0.5056 0.9061 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G02 compound treatment 280350.0 -76300.0 -0.52 297440.0 2210.0 0.02 -0.3532 -0.6849 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G03 mock treatment 410450.0 53800.0 0.36 361310.0 66100.0 0.48 0.5953 0.9908 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G04 mock treatment 439130.0 82500.0 0.56 347010.0 51800.0 0.37 0.6591 0.9814 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G05 compound treatment 307460.0 -49200.0 -0.33 289060.0 -6170.0 -0.04 -0.2666 -0.795 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G06 compound treatment 367470.0 10800.0 0.07 397480.0 102000.0 0.74 0.5751 0.7732 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G07 compound treatment 228380.0 -128000.0 -0.87 206450.0 -88800.0 -0.64 -1.0673 -0.9892 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G08 compound treatment 368430.0 11800.0 0.08 321650.0 26400.0 0.19 0.1915 0.9246 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G09 compound treatment 309310.0 -47300.0 -0.32 314880.0 19600.0 0.14 -0.1256 -0.3588 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G10 compound treatment 387000.0 30400.0 0.21 393280.0 98000.0 0.71 0.6469 0.8756 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G11 compound treatment 263770.0 -92900.0 -0.63 247250.0 -48000.0 -0.35 -0.6894 -0.9611 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G12 compound treatment 274370.0 -82300.0 -0.56 228760.0 -66500.0 -0.48 -0.7334 -0.9974 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G13 compound treatment 426560.0 69900.0 0.47 340410.0 45200.0 0.33 0.5653 0.9839 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G14 compound treatment 280360.0 -76300.0 -0.52 175870.0 -119000.0 -0.86 -0.9755 -0.9695 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G15 compound treatment 411520.0 54900.0 0.37 260800.0 -34400.0 -0.25 0.0859 0.1923 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G16 compound treatment 431120.0 74500.0 0.5 311770.0 16500.0 0.12 0.4405 0.8516 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G17 compound treatment 341150.0 -15500.0 -0.1 256180.0 -39100.0 -0.28 -0.274 -0.9087 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G18 compound treatment 332160.0 -24500.0 -0.17 324190.0 29000.0 0.21 0.0312 0.1169 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G19 mock treatment 413380.0 56700.0 0.38 289560.0 -5670.0 -0.04 0.242 0.6277 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G20 mock treatment 276830.0 -79800.0 -0.54 257120.0 -38100.0 -0.28 -0.5765 -0.9516 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G21 compound treatment 267950.0 -88700.0 -0.6 281120.0 -14100.0 -0.1 -0.496 -0.8159 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G22 compound treatment 297340.0 -59300.0 -0.4 246090.0 -49100.0 -0.36 -0.5349 -0.9982 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G23 compound treatment 318360.0 -38300.0 -0.26 241440.0 -53800.0 -0.39 -0.4583 -0.9803 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 G24 compound treatment 227230.0 -129000.0 -0.87 137840.0 -157000.0 -1.14 -1.424 -0.9915 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H01 compound treatment 397540.0 40900.0 0.28 293670.0 -1560.0 -0.01 0.1874 0.6776 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H02 compound treatment 445180.0 88500.0 0.6 345720.0 50500.0 0.37 0.6814 0.9721 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H03 mock treatment 424410.0 67800.0 0.46 367240.0 72000.0 0.52 0.6923 0.9979 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H04 mock treatment 425040.0 68400.0 0.46 379270.0 84000.0 0.61 0.7569 0.9908 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H05 compound treatment 159380.0 -197000.0 -1.33 193150.0 -102000.0 -0.74 -1.465 -0.9613 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H06 compound treatment 423200.0 66600.0 0.45 258750.0 -36500.0 -0.26 0.1312 0.2516 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H07 compound treatment 360160.0 3510.0 0.02 348820.0 53600.0 0.39 0.2911 0.749 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H08 compound treatment 379680.0 23000.0 0.16 169880.0 -125000.0 -0.91 -0.5316 -0.5774 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H09 compound treatment 197670.0 -159000.0 -1.07 217290.0 -77900.0 -0.56 -1.1585 -0.9548 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H10 compound treatment 453810.0 97200.0 0.66 379360.0 84100.0 0.61 0.8948 0.9993 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H11 compound treatment 142580.0 -214000.0 -1.45 179790.0 -115000.0 -0.84 -1.6137 -0.966 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H12 compound treatment 155260.0 -201000.0 -1.36 251930.0 -43300.0 -0.31 -1.1839 -0.8478 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H13 compound treatment 324800.0 -31800.0 -0.22 201330.0 -93900.0 -0.68 -0.6328 -0.8875 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H14 compound treatment 268250.0 -88400.0 -0.6 229790.0 -65400.0 -0.47 -0.7573 -0.9934 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H15 compound treatment 343240.0 -13400.0 -0.09 319300.0 24100.0 0.17 0.0591 0.3011 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H16 compound treatment 304330.0 -52300.0 -0.35 253230.0 -42000.0 -0.3 -0.465 -0.9972 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H17 compound treatment 379680.0 23000.0 0.16 258620.0 -36600.0 -0.27 -0.0774 -0.2517 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H18 compound treatment 348350.0 -8300.0 -0.06 248170.0 -47100.0 -0.34 -0.2806 -0.8126 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H19 mock treatment 428740.0 72100.0 0.49 266240.0 -29000.0 -0.21 0.196 0.3696 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H20 mock treatment 385870.0 29200.0 0.2 271260.0 -24000.0 -0.17 0.0169 0.0643 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H21 compound treatment 300720.0 -55900.0 -0.38 341490.0 46300.0 0.33 -0.0304 -0.0603 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H22 compound treatment 294720.0 -61900.0 -0.42 314080.0 18800.0 0.14 -0.1994 -0.4531 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H23 compound treatment 347390.0 -9260.0 -0.06 265980.0 -29300.0 -0.21 -0.194 -0.8785 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 H24 compound treatment 298360.0 -58300.0 -0.39 245090.0 -50100.0 -0.36 -0.5352 -0.9992 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I01 compound treatment 261760.0 -94900.0 -0.64 276700.0 -18500.0 -0.13 -0.5482 -0.8369 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I02 compound treatment 439570.0 82900.0 0.56 267360.0 -27900.0 -0.2 0.2535 0.4257 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I03 compound treatment 337810.0 -18800.0 -0.13 171480.0 -124000.0 -0.9 -0.7235 -0.7995 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I04 compound treatment 354150.0 -2500.0 -0.02 268800.0 -26400.0 -0.19 -0.1472 -0.7665 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I05 mock treatment 202400.0 -154000.0 -1.04 377180.0 81900.0 0.59 -0.3175 -0.2648 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I06 mock treatment 411750.0 55100.0 0.37 351630.0 56400.0 0.41 0.5519 0.9989 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I07 compound treatment 197520.0 -159000.0 -1.08 275600.0 -19600.0 -0.14 -0.8608 -0.7937 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I08 compound treatment 303040.0 -53600.0 -0.36 187560.0 -108000.0 -0.78 -0.8073 -0.9392 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I09 compound treatment 415360.0 58700.0 0.4 369820.0 74600.0 0.54 0.6623 0.9885 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I10 compound treatment 289620.0 -67000.0 -0.45 321240.0 26000.0 0.19 -0.1871 -0.3815 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I11 compound treatment 413870.0 57200.0 0.39 261850.0 -33400.0 -0.24 0.1025 0.2248 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I12 compound treatment 280380.0 -76300.0 -0.52 169440.0 -126000.0 -0.91 -1.0083 -0.9637 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I13 compound treatment 373600.0 17000.0 0.11 298940.0 3710.0 0.03 0.1 0.8497 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I14 compound treatment 297700.0 -58900.0 -0.4 242180.0 -53100.0 -0.38 -0.5532 -0.9998 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I15 compound treatment 321490.0 -35200.0 -0.24 288270.0 -6960.0 -0.05 -0.2036 -0.8385 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I16 compound treatment 269330.0 -87300.0 -0.59 212760.0 -82500.0 -0.6 -0.8393 -1.0 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I17 compound treatment 316020.0 -40600.0 -0.27 235870.0 -59400.0 -0.43 -0.498 -0.9766 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I18 compound treatment 307790.0 -48900.0 -0.33 311620.0 16400.0 0.12 -0.1496 -0.4263 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I19 compound treatment 354630.0 -2020.0 -0.01 302510.0 7280.0 0.05 0.0276 0.5073 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I20 compound treatment 307790.0 -48900.0 -0.33 335680.0 40400.0 0.29 -0.0264 -0.0598 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I21 mock treatment 405500.0 48900.0 0.33 335100.0 39900.0 0.29 0.4375 0.9978 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I22 mock treatment 356540.0 -109.0 0.0 381970.0 86700.0 0.63 0.4435 0.7063 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I23 compound treatment 267210.0 -89400.0 -0.6 275730.0 -19500.0 -0.14 -0.5272 -0.8494 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 I24 compound treatment 298350.0 -58300.0 -0.39 243300.0 -51900.0 -0.38 -0.5444 -0.9997 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J01 compound treatment 222120.0 -135000.0 -0.91 251360.0 -43900.0 -0.32 -0.8673 -0.9008 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J02 compound treatment 245960.0 -111000.0 -0.75 224600.0 -70600.0 -0.51 -0.8904 -0.9828 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J03 compound treatment 389770.0 33100.0 0.22 346440.0 51200.0 0.37 0.4204 0.9708 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J04 compound treatment 390740.0 34100.0 0.23 242880.0 -52400.0 -0.38 -0.1051 -0.237 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J05 mock treatment 367840.0 11200.0 0.08 222850.0 -72400.0 -0.52 -0.317 -0.5989 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J06 mock treatment 298100.0 -58500.0 -0.4 306110.0 10900.0 0.08 -0.2241 -0.5555 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J07 compound treatment 238180.0 -118000.0 -0.8 338990.0 43800.0 0.32 -0.342 -0.3973 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J08 compound treatment 181280.0 -175000.0 -1.18 216750.0 -78500.0 -0.57 -1.2396 -0.9433 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J09 compound treatment 243750.0 -113000.0 -0.76 160660.0 -135000.0 -0.97 -1.2282 -0.9927 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J10 compound treatment 265450.0 -91200.0 -0.62 284960.0 -10300.0 -0.07 -0.4883 -0.7867 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J11 compound treatment 239710.0 -117000.0 -0.79 153470.0 -142000.0 -1.03 -1.2844 -0.9917 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J12 compound treatment 203520.0 -153000.0 -1.03 85700.0 -210000.0 -1.52 -1.8042 -0.9826 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J13 compound treatment 336750.0 -19900.0 -0.13 223650.0 -71600.0 -0.52 -0.4615 -0.862 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J14 compound treatment 277820.0 -78800.0 -0.53 265070.0 -30200.0 -0.22 -0.531 -0.9225 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J15 compound treatment 246610.0 -110000.0 -0.74 325480.0 30200.0 0.22 -0.3709 -0.4786 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J16 compound treatment 363720.0 7070.0 0.05 302170.0 6940.0 0.05 0.0693 0.9997 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J17 compound treatment 228750.0 -128000.0 -0.86 95440.0 -200000.0 -1.45 -1.6338 -0.9697 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J18 compound treatment 417660.0 61000.0 0.41 301400.0 6170.0 0.04 0.3231 0.7791 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J19 compound treatment 364810.0 8160.0 0.06 247530.0 -47700.0 -0.35 -0.2052 -0.5868 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J20 compound treatment 230580.0 -126000.0 -0.85 201440.0 -93800.0 -0.68 -1.0824 -0.9937 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J21 mock treatment 333050.0 -23600.0 -0.16 260040.0 -35200.0 -0.25 -0.2929 -0.9745 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J22 mock treatment 361850.0 5200.0 0.04 264990.0 -30200.0 -0.22 -0.13 -0.5861 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J23 compound treatment 242610.0 -114000.0 -0.77 248570.0 -46700.0 -0.34 -0.7837 -0.9315 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 J24 compound treatment 255680.0 -101000.0 -0.68 215200.0 -80000.0 -0.58 -0.8921 -0.9967 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K01 compound treatment 217620.0 -139000.0 -0.94 391300.0 96100.0 0.7 -0.1725 -0.1476 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K02 compound treatment 398680.0 42000.0 0.28 285300.0 -9930.0 -0.07 0.15 0.5119 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K03 compound treatment 396800.0 40200.0 0.27 368960.0 73700.0 0.53 0.5692 0.9508 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K04 compound treatment 339590.0 -17100.0 -0.12 232960.0 -62300.0 -0.45 -0.4003 -0.8602 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K05 compound treatment 387880.0 31200.0 0.21 180120.0 -115000.0 -0.83 -0.44 -0.5119 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K06 compound treatment 404850.0 48200.0 0.33 249050.0 -46200.0 -0.33 -0.0061 -0.0131 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K07 mock treatment 378240.0 21600.0 0.15 432320.0 137000.0 0.99 0.8049 0.8024 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K08 mock treatment 231950.0 -125000.0 -0.84 240340.0 -54900.0 -0.4 -0.8768 -0.9412 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K09 compound treatment 244110.0 -113000.0 -0.76 158640.0 -137000.0 -0.99 -1.2369 -0.9916 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K10 compound treatment 126940.0 -230000.0 -1.55 155590.0 -140000.0 -1.01 -1.8123 -0.9784 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K11 compound treatment 445130.0 88500.0 0.6 399400.0 104000.0 0.75 0.9559 0.9934 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K12 compound treatment 410150.0 53500.0 0.36 299470.0 4240.0 0.03 0.2773 0.7643 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K13 compound treatment 243430.0 -113000.0 -0.76 192480.0 -103000.0 -0.74 -1.0669 -0.9999 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K14 compound treatment 403680.0 47000.0 0.32 322500.0 27300.0 0.2 0.3643 0.9738 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K15 mock treatment 316560.0 -40100.0 -0.27 326250.0 31000.0 0.22 -0.0328 -0.0931 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K16 mock treatment 541280.0 185000.0 1.25 304100.0 8870.0 0.06 0.9275 0.7425 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K17 compound treatment 351360.0 -5290.0 -0.04 270530.0 -24700.0 -0.18 -0.1517 -0.832 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K18 compound treatment 281680.0 -75000.0 -0.51 264320.0 -30900.0 -0.22 -0.5164 -0.9325 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K19 compound treatment 323360.0 -33300.0 -0.22 326470.0 31200.0 0.23 8.0E-4 0.0026 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K20 compound treatment 344160.0 -12500.0 -0.08 300810.0 5580.0 0.04 -0.0311 -0.3327 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K21 compound treatment 274950.0 -81700.0 -0.55 230200.0 -65000.0 -0.47 -0.7232 -0.9969 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K22 compound treatment 284820.0 -71800.0 -0.49 238470.0 -56800.0 -0.41 -0.6337 -0.9966 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K23 mock treatment 212580.0 -144000.0 -0.97 217530.0 -77700.0 -0.56 -1.0861 -0.966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 K24 mock treatment 382280.0 25600.0 0.17 335590.0 40400.0 0.29 0.329 0.9688 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L01 compound treatment 283360.0 -73300.0 -0.5 294770.0 -464.0 0.0 -0.3525 -0.7119 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L02 compound treatment 310960.0 -45700.0 -0.31 236020.0 -59200.0 -0.43 -0.5214 -0.987 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L03 compound treatment 18150.0 -338000.0 -2.29 181870.0 -113000.0 -0.82 -2.1976 -0.9044 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L04 compound treatment 289190.0 -67500.0 -0.46 347090.0 51900.0 0.38 -0.0569 -0.0963 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L05 compound treatment 333030.0 -23600.0 -0.16 359920.0 64700.0 0.47 0.2183 0.4412 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L06 compound treatment 269070.0 -87600.0 -0.59 324260.0 29000.0 0.21 -0.2699 -0.4297 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L07 mock treatment 305470.0 -51200.0 -0.35 420810.0 126000.0 0.91 0.3983 0.4095 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L08 mock treatment 423250.0 66600.0 0.45 356820.0 61600.0 0.45 0.6334 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L09 compound treatment 305970.0 -50700.0 -0.34 397630.0 102000.0 0.74 0.282 0.3454 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L10 compound treatment 398310.0 41700.0 0.28 370840.0 75600.0 0.55 0.5861 0.9522 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L11 compound treatment 513280.0 157000.0 1.06 278130.0 -17100.0 -0.12 0.6608 0.6202 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L12 compound treatment 195470.0 -161000.0 -1.09 304830.0 9600.0 0.07 -0.721 -0.6607 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L13 compound treatment 359290.0 2640.0 0.02 317540.0 22300.0 0.16 0.1268 0.7805 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L14 compound treatment 362050.0 5400.0 0.04 363680.0 68400.0 0.5 0.3762 0.7571 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L15 mock treatment 387560.0 30900.0 0.21 275940.0 -19300.0 -0.14 0.0489 0.1947 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L16 mock treatment 276960.0 -79700.0 -0.54 275090.0 -20100.0 -0.15 -0.4838 -0.8674 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L17 compound treatment 388190.0 31500.0 0.21 259310.0 -35900.0 -0.26 -0.0332 -0.0987 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L18 compound treatment 298560.0 -58100.0 -0.39 244510.0 -50700.0 -0.37 -0.5372 -0.9994 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L19 compound treatment 310330.0 -46300.0 -0.31 284640.0 -10600.0 -0.08 -0.2755 -0.8551 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L20 compound treatment 265280.0 -91400.0 -0.62 208430.0 -86800.0 -0.63 -0.8809 -1.0 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L21 compound treatment 381600.0 25000.0 0.17 336660.0 41400.0 0.3 0.3313 0.9629 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L22 compound treatment 281440.0 -75200.0 -0.51 323400.0 28200.0 0.2 -0.2152 -0.3929 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L23 mock treatment 380840.0 24200.0 0.16 230000.0 -65200.0 -0.47 -0.2183 -0.4369 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 L24 mock treatment 407370.0 50700.0 0.34 335370.0 40100.0 0.29 0.4478 0.9966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M01 compound treatment 349470.0 -7180.0 -0.05 304960.0 9730.0 0.07 0.0155 0.1811 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M02 compound treatment 368110.0 11500.0 0.08 317730.0 22500.0 0.16 0.1699 0.9423 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M03 compound treatment 340800.0 -15800.0 -0.11 237080.0 -58200.0 -0.42 -0.3734 -0.8596 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M04 compound treatment 258740.0 -97900.0 -0.66 167970.0 -127000.0 -0.92 -1.1192 -0.9868 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M05 compound treatment 376850.0 20200.0 0.14 389140.0 93900.0 0.68 0.5772 0.8325 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M06 compound treatment 237480.0 -119000.0 -0.81 342800.0 47600.0 0.34 -0.3259 -0.3721 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M07 compound treatment 223910.0 -133000.0 -0.9 182320.0 -113000.0 -0.82 -1.2122 -0.9989 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M08 compound treatment 230660.0 -126000.0 -0.85 284190.0 -11000.0 -0.08 -0.6585 -0.7701 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M09 mock treatment 444660.0 88000.0 0.59 337800.0 42600.0 0.31 0.6384 0.9531 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M10 mock treatment 357570.0 921.0 0.01 314840.0 19600.0 0.14 0.1048 0.7374 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M11 compound treatment 204190.0 -152000.0 -1.03 179240.0 -116000.0 -0.84 -1.3222 -0.9949 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M12 compound treatment 115200.0 -241000.0 -1.63 104640.0 -191000.0 -1.38 -2.1292 -0.9965 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M13 mock treatment 480130.0 123000.0 0.83 387200.0 92000.0 0.67 1.0607 0.9937 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M14 mock treatment 463780.0 107000.0 0.72 263430.0 -31800.0 -0.23 0.3491 0.4595 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M15 compound treatment 387160.0 30500.0 0.21 311840.0 16600.0 0.12 0.2308 0.967 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M16 compound treatment 372210.0 15600.0 0.11 293680.0 -1550.0 -0.01 0.0664 0.6279 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M17 compound treatment 250370.0 -106000.0 -0.72 218880.0 -76400.0 -0.55 -0.8986 -0.9916 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M18 compound treatment 312410.0 -44200.0 -0.3 190730.0 -105000.0 -0.76 -0.7463 -0.9175 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M19 compound treatment 15120.0 -342000.0 -2.31 6680.0 -289000.0 -2.09 -3.1088 -0.9988 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M20 compound treatment 398450.0 41800.0 0.28 377040.0 81800.0 0.59 0.6185 0.9426 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M21 compound treatment 247900.0 -109000.0 -0.73 240450.0 -54800.0 -0.4 -0.8 -0.9581 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M22 compound treatment 260350.0 -96300.0 -0.65 232330.0 -62900.0 -0.46 -0.7821 -0.9848 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M23 compound treatment 333320.0 -23300.0 -0.16 229030.0 -66200.0 -0.48 -0.4503 -0.8926 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 M24 compound treatment 243850.0 -113000.0 -0.76 202910.0 -92300.0 -0.67 -1.0115 -0.9979 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N01 compound treatment 291880.0 -64800.0 -0.44 335950.0 40700.0 0.29 -0.101 -0.1915 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N02 compound treatment 383160.0 26500.0 0.18 321440.0 26200.0 0.19 0.2608 0.9996 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N03 compound treatment 369660.0 13000.0 0.09 400480.0 105000.0 0.76 0.6009 0.7835 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N04 compound treatment 282240.0 -74400.0 -0.5 243720.0 -51500.0 -0.37 -0.6192 -0.9892 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N05 compound treatment 217080.0 -140000.0 -0.94 304850.0 9620.0 0.07 -0.6176 -0.6531 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N06 compound treatment 442370.0 85700.0 0.58 238630.0 -56600.0 -0.41 0.1198 0.1689 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N07 compound treatment 390170.0 33500.0 0.23 288900.0 -6330.0 -0.05 0.1277 0.5528 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N08 compound treatment 231910.0 -125000.0 -0.84 305310.0 10100.0 0.07 -0.5444 -0.6435 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N09 mock treatment 439440.0 82800.0 0.56 320960.0 25700.0 0.19 0.5272 0.8943 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N10 mock treatment 376020.0 19400.0 0.13 335130.0 39900.0 0.29 0.2968 0.9359 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N11 compound treatment 335790.0 -20900.0 -0.14 352960.0 57700.0 0.42 0.1958 0.444 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N12 compound treatment 250240.0 -106000.0 -0.72 228520.0 -66700.0 -0.48 -0.8499 -0.9813 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N13 mock treatment 442050.0 85400.0 0.58 383600.0 88400.0 0.64 0.8604 0.9987 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N14 mock treatment 321210.0 -35400.0 -0.24 312260.0 17000.0 0.12 -0.0822 -0.3051 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N15 compound treatment 289640.0 -67000.0 -0.45 319840.0 24600.0 0.18 -0.1942 -0.3991 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N16 compound treatment 238170.0 -118000.0 -0.8 208430.0 -86800.0 -0.63 -1.0104 -0.9928 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N17 compound treatment 289670.0 -67000.0 -0.45 281350.0 -13900.0 -0.1 -0.3911 -0.8436 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N18 compound treatment 211420.0 -145000.0 -0.98 196880.0 -98400.0 -0.71 -1.1973 -0.9876 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N19 compound treatment 302460.0 -54200.0 -0.37 216130.0 -79100.0 -0.57 -0.6638 -0.9767 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N20 compound treatment 294410.0 -62200.0 -0.42 325770.0 30500.0 0.22 -0.1411 -0.2969 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N21 compound treatment 282240.0 -74400.0 -0.5 304050.0 8820.0 0.06 -0.3104 -0.6124 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N22 compound treatment 290120.0 -66500.0 -0.45 258200.0 -37000.0 -0.27 -0.5074 -0.9695 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N23 compound treatment 315010.0 -41600.0 -0.28 241350.0 -53900.0 -0.39 -0.4748 -0.9871 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 N24 compound treatment 294330.0 -62300.0 -0.42 186850.0 -108000.0 -0.78 -0.8525 -0.9574 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O01 compound treatment 318460.0 -38200.0 -0.26 315380.0 20100.0 0.15 -0.0793 -0.2677 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O02 compound treatment 290410.0 -66200.0 -0.45 309790.0 14600.0 0.11 -0.242 -0.5262 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O03 compound treatment 271570.0 -85100.0 -0.57 260220.0 -35000.0 -0.25 -0.5857 -0.9323 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O04 compound treatment 194820.0 -162000.0 -1.09 184650.0 -111000.0 -0.8 -1.3392 -0.9882 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O05 compound treatment 360230.0 3580.0 0.02 273250.0 -22000.0 -0.16 -0.0954 -0.5928 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O06 compound treatment 191040.0 -166000.0 -1.12 308370.0 13100.0 0.1 -0.724 -0.6447 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O07 compound treatment 292800.0 -63800.0 -0.43 216120.0 -79100.0 -0.57 -0.71 -0.9902 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O08 compound treatment 304540.0 -52100.0 -0.35 264590.0 -30600.0 -0.22 -0.4058 -0.9752 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O09 compound treatment 374840.0 18200.0 0.12 282490.0 -12700.0 -0.09 0.0217 0.1411 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O10 compound treatment 352040.0 -4610.0 -0.03 228010.0 -67200.0 -0.49 -0.3661 -0.7508 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O11 mock treatment 253280.0 -103000.0 -0.7 288690.0 -6540.0 -0.05 -0.5274 -0.7533 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O12 mock treatment 302400.0 -54200.0 -0.37 279610.0 -15600.0 -0.11 -0.3392 -0.8842 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O13 compound treatment 270730.0 -85900.0 -0.58 206490.0 -88700.0 -0.64 -0.8648 -0.9987 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O14 compound treatment 315260.0 -41400.0 -0.28 222790.0 -72400.0 -0.52 -0.5686 -0.9567 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O15 compound treatment 235060.0 -122000.0 -0.82 196490.0 -98700.0 -0.71 -1.0864 -0.9976 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O16 compound treatment 226760.0 -130000.0 -0.88 198460.0 -96800.0 -0.7 -1.1159 -0.9938 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O17 compound treatment 303170.0 -53500.0 -0.36 271380.0 -23900.0 -0.17 -0.3776 -0.9429 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O18 compound treatment 271250.0 -85400.0 -0.58 221690.0 -73500.0 -0.53 -0.7845 -0.9992 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O19 compound treatment 229240.0 -127000.0 -0.86 197800.0 -97400.0 -0.71 -1.1075 -0.9951 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O20 compound treatment 280360.0 -76300.0 -0.52 223440.0 -71800.0 -0.52 -0.732 -1.0 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O21 compound treatment 197250.0 -159000.0 -1.08 190140.0 -105000.0 -0.76 -1.2995 -0.9855 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O22 compound treatment 196640.0 -160000.0 -1.08 206920.0 -88300.0 -0.64 -1.2165 -0.9686 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O23 compound treatment 116960.0 -240000.0 -1.62 26930.0 -268000.0 -1.94 -2.5186 -0.9959 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 O24 compound treatment 268520.0 -88100.0 -0.6 204020.0 -91200.0 -0.66 -0.888 -0.9987 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P01 compound treatment 158770.0 -198000.0 -1.34 198150.0 -97100.0 -0.7 -1.4424 -0.9549 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P02 compound treatment 225950.0 -131000.0 -0.88 207840.0 -87400.0 -0.63 -1.0718 -0.9866 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P03 compound treatment 271570.0 -85100.0 -0.57 231520.0 -63700.0 -0.46 -0.7326 -0.994 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P04 compound treatment 219310.0 -137000.0 -0.93 249280.0 -46000.0 -0.33 -0.8914 -0.9042 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P05 compound treatment 16880.0 -340000.0 -2.3 23710.0 -272000.0 -1.97 -3.0132 -0.997 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P06 compound treatment 205330.0 -151000.0 -1.02 233330.0 -61900.0 -0.45 -1.0398 -0.9315 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P07 compound treatment 265760.0 -90900.0 -0.61 236070.0 -59200.0 -0.43 -0.7371 -0.9845 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P08 compound treatment 317770.0 -38900.0 -0.26 203700.0 -91500.0 -0.66 -0.6543 -0.9179 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P09 compound treatment 213980.0 -143000.0 -0.96 254900.0 -40300.0 -0.29 -0.8881 -0.8817 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P10 compound treatment 290530.0 -66100.0 -0.45 244610.0 -50600.0 -0.37 -0.575 -0.9952 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P11 mock treatment 239160.0 -117000.0 -0.79 212100.0 -83100.0 -0.6 -0.9869 -0.9907 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P12 mock treatment 175420.0 -181000.0 -1.22 229470.0 -65800.0 -0.48 -1.2025 -0.9153 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P13 compound treatment 237200.0 -119000.0 -0.81 195390.0 -99800.0 -0.72 -1.0818 -0.9985 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P14 compound treatment 252980.0 -104000.0 -0.7 206720.0 -88500.0 -0.64 -0.9484 -0.999 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P15 compound treatment 206080.0 -151000.0 -1.02 260270.0 -35000.0 -0.25 -0.8984 -0.8569 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P16 compound treatment 227930.0 -129000.0 -0.87 173600.0 -122000.0 -0.88 -1.2376 -1.0 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P17 compound treatment 258280.0 -98400.0 -0.66 266840.0 -28400.0 -0.21 -0.6153 -0.8844 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P18 compound treatment 40690.0 -316000.0 -2.13 66500.0 -229000.0 -1.66 -2.6804 -0.9921 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P19 compound treatment 214460.0 -142000.0 -0.96 200960.0 -94300.0 -0.68 -1.1619 -0.986 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P20 compound treatment 196380.0 -160000.0 -1.08 164290.0 -131000.0 -0.95 -1.436 -0.9978 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P21 compound treatment 225960.0 -131000.0 -0.88 151580.0 -144000.0 -1.04 -1.3597 -0.9967 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P22 compound treatment 212410.0 -144000.0 -0.97 169220.0 -126000.0 -0.91 -1.3342 -0.9995 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P23 compound treatment 206180.0 -150000.0 -1.02 195290.0 -99900.0 -0.72 -1.2305 -0.9861 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2097 P24 compound treatment 230580.0 -126000.0 -0.85 195040.0 -100000.0 -0.73 -1.1152 -0.9968 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A01 compound treatment 275080.0 -80600.0 -0.54 279880.0 -49300.0 -0.36 -0.6372 -0.979 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A02 compound treatment 325240.0 -30400.0 -0.21 329970.0 800.0 0.01 -0.1411 -0.6869 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A03 compound treatment 315140.0 -40500.0 -0.27 253930.0 -75200.0 -0.54 -0.5786 -0.9493 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A04 compound treatment 333340.0 -22300.0 -0.15 383520.0 54400.0 0.39 0.1717 0.4075 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A05 compound treatment 206460.0 -149000.0 -1.01 154470.0 -175000.0 -1.26 -1.607 -0.9937 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A06 compound treatment 322260.0 -33400.0 -0.23 232320.0 -96800.0 -0.7 -0.6552 -0.8897 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A07 compound treatment 209160.0 -146000.0 -0.99 397700.0 68500.0 0.5 -0.349 -0.3153 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A08 compound treatment 188490.0 -167000.0 -1.13 206770.0 -122000.0 -0.89 -1.4251 -0.9928 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A09 compound treatment 392740.0 37100.0 0.25 312810.0 -16400.0 -0.12 0.0935 0.3374 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A10 compound treatment 236690.0 -119000.0 -0.8 340960.0 11800.0 0.09 -0.5079 -0.6285 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A11 compound treatment 213600.0 -142000.0 -0.96 214030.0 -115000.0 -0.83 -1.268 -0.9975 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A12 compound treatment 293450.0 -62200.0 -0.42 325490.0 -3680.0 -0.03 -0.3159 -0.7504 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A13 mock treatment 301280.0 -54400.0 -0.37 334350.0 5180.0 0.04 -0.2332 -0.6316 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A14 mock treatment 358090.0 2460.0 0.02 248800.0 -80400.0 -0.58 -0.3996 -0.6866 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A15 compound treatment 303970.0 -51700.0 -0.35 265560.0 -63600.0 -0.46 -0.5724 -0.9907 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A16 compound treatment 241210.0 -114000.0 -0.77 242100.0 -87100.0 -0.63 -0.9924 -0.9949 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A17 compound treatment 315680.0 -40000.0 -0.27 224740.0 -104000.0 -0.76 -0.7254 -0.9037 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A18 compound treatment 299770.0 -55900.0 -0.38 272660.0 -56500.0 -0.41 -0.5562 -0.9992 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A19 compound treatment 236850.0 -119000.0 -0.8 281340.0 -47800.0 -0.35 -0.8123 -0.9294 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A20 compound treatment 250770.0 -105000.0 -0.71 212640.0 -117000.0 -0.84 -1.0975 -0.9962 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A21 compound treatment 136520.0 -219000.0 -1.48 129060.0 -200000.0 -1.45 -2.0712 -0.9999 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A22 compound treatment 258810.0 -96800.0 -0.65 306880.0 -22300.0 -0.16 -0.5767 -0.8559 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A23 compound treatment 283530.0 -72100.0 -0.49 217020.0 -112000.0 -0.81 -0.9186 -0.9702 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 A24 compound treatment 215360.0 -140000.0 -0.95 182420.0 -147000.0 -1.06 -1.4214 -0.9984 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B01 compound treatment 119680.0 -236000.0 -1.59 175000.0 -154000.0 -1.12 -1.9165 -0.9848 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B02 compound treatment 391300.0 35700.0 0.24 400430.0 71300.0 0.52 0.5352 0.9399 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B03 compound treatment 355360.0 -273.0 0.0 310370.0 -18800.0 -0.14 -0.0975 -0.7166 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B04 compound treatment 395550.0 39900.0 0.27 405730.0 76600.0 0.55 0.5826 0.9452 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B05 compound treatment 360560.0 4930.0 0.03 309530.0 -19600.0 -0.14 -0.077 -0.5273 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B06 compound treatment 248860.0 -107000.0 -0.72 269800.0 -59400.0 -0.43 -0.814 -0.9694 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B07 compound treatment 378620.0 23000.0 0.16 301080.0 -28100.0 -0.2 -0.034 -0.1327 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B08 compound treatment 358890.0 3260.0 0.02 273710.0 -55500.0 -0.4 -0.2683 -0.6673 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B09 compound treatment 351900.0 -3730.0 -0.03 349600.0 20400.0 0.15 0.0867 0.5782 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B10 compound treatment 427300.0 71700.0 0.48 353140.0 24000.0 0.17 0.4651 0.9042 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B11 compound treatment 437370.0 81700.0 0.55 389130.0 60000.0 0.43 0.6974 0.9929 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B12 compound treatment 261600.0 -94000.0 -0.64 212180.0 -117000.0 -0.85 -1.0481 -0.99 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B13 mock treatment 416850.0 61200.0 0.41 340830.0 11700.0 0.08 0.3522 0.8342 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B14 mock treatment 362620.0 6990.0 0.05 331250.0 2080.0 0.02 0.044 0.8886 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B15 compound treatment 288090.0 -67500.0 -0.46 269250.0 -59900.0 -0.43 -0.6294 -0.9997 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B16 compound treatment 419360.0 63700.0 0.43 398440.0 69300.0 0.5 0.659 0.9971 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B17 compound treatment 340590.0 -15000.0 -0.1 330490.0 1320.0 0.01 -0.0651 -0.6378 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B18 compound treatment 375440.0 19800.0 0.13 368850.0 39700.0 0.29 0.2977 0.9396 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B19 compound treatment 296320.0 -59300.0 -0.4 262300.0 -66900.0 -0.48 -0.6257 -0.9956 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B20 compound treatment 133890.0 -222000.0 -1.5 119700.0 -209000.0 -1.52 -2.1317 -1.0 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B21 compound treatment 387940.0 32300.0 0.22 375480.0 46300.0 0.34 0.3914 0.9784 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B22 compound treatment 334980.0 -20700.0 -0.14 398520.0 69400.0 0.5 0.2563 0.4919 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B23 compound treatment 301850.0 -53800.0 -0.36 351610.0 22400.0 0.16 -0.1421 -0.357 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 B24 compound treatment 309250.0 -46400.0 -0.31 287450.0 -41700.0 -0.3 -0.4352 -0.9998 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C01 compound treatment 275060.0 -80600.0 -0.54 269760.0 -59400.0 -0.43 -0.6891 -0.9932 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C02 compound treatment 280540.0 -75100.0 -0.51 314410.0 -14800.0 -0.11 -0.4343 -0.8376 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C03 compound treatment 295360.0 -60300.0 -0.41 228600.0 -101000.0 -0.73 -0.8028 -0.9623 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C04 compound treatment 155780.0 -200000.0 -1.35 181150.0 -148000.0 -1.07 -1.7125 -0.9934 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C05 compound treatment 223200.0 -132000.0 -0.89 222460.0 -107000.0 -0.77 -1.179 -0.9973 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C06 compound treatment 288380.0 -67300.0 -0.45 254400.0 -74800.0 -0.54 -0.704 -0.9962 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C07 compound treatment 268390.0 -87200.0 -0.59 289600.0 -39600.0 -0.29 -0.6194 -0.945 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C08 compound treatment 299040.0 -56600.0 -0.38 273070.0 -56100.0 -0.41 -0.5575 -0.9995 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C09 compound treatment 181120.0 -175000.0 -1.18 181000.0 -148000.0 -1.07 -1.5922 -0.9989 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C10 compound treatment 131730.0 -224000.0 -1.51 101870.0 -227000.0 -1.65 -2.2332 -0.9991 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C11 mock treatment 381230.0 25600.0 0.17 391910.0 62700.0 0.45 0.4434 0.9125 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C12 mock treatment 300160.0 -55500.0 -0.37 363370.0 34200.0 0.25 -0.09 -0.2003 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C13 compound treatment 149440.0 -206000.0 -1.39 154900.0 -174000.0 -1.26 -1.8772 -0.9988 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C14 compound treatment 393220.0 37600.0 0.25 349600.0 20400.0 0.15 0.2842 0.9669 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C15 mock treatment 472160.0 117000.0 0.79 298120.0 -31000.0 -0.22 0.3978 0.4858 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C16 mock treatment 378050.0 22400.0 0.15 295600.0 -33600.0 -0.24 -0.0647 -0.226 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C17 compound treatment 283490.0 -72100.0 -0.49 304840.0 -24300.0 -0.18 -0.4692 -0.9053 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C18 compound treatment 323910.0 -31700.0 -0.21 236500.0 -92700.0 -0.67 -0.6259 -0.8888 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C19 compound treatment 80260.0 -275000.0 -1.86 103090.0 -226000.0 -1.64 -2.4729 -0.998 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C20 compound treatment 279220.0 -76400.0 -0.52 227170.0 -102000.0 -0.74 -0.8872 -0.9847 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C21 compound treatment 182180.0 -173000.0 -1.17 184990.0 -144000.0 -1.04 -1.5667 -0.9983 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C22 compound treatment 231430.0 -124000.0 -0.84 227360.0 -102000.0 -0.74 -1.1146 -0.9979 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C23 compound treatment 293700.0 -61900.0 -0.42 342960.0 13800.0 0.1 -0.2253 -0.5237 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 C24 compound treatment 279620.0 -76000.0 -0.51 296270.0 -32900.0 -0.24 -0.5316 -0.939 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D01 compound treatment 337120.0 -18500.0 -0.13 332420.0 3250.0 0.02 -0.0718 -0.5642 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D02 compound treatment 192320.0 -163000.0 -1.1 228350.0 -101000.0 -0.73 -1.2963 -0.9799 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D03 compound treatment 356850.0 1220.0 0.01 410680.0 81500.0 0.59 0.423 0.7169 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D04 compound treatment 426260.0 70600.0 0.48 301610.0 -27600.0 -0.2 0.1964 0.3797 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D05 compound treatment 316090.0 -39500.0 -0.27 229400.0 -99800.0 -0.72 -0.6996 -0.9085 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D06 compound treatment 180010.0 -176000.0 -1.19 147930.0 -181000.0 -1.31 -1.7668 -0.9987 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D07 compound treatment 258240.0 -97400.0 -0.66 240190.0 -89000.0 -0.64 -0.9208 -0.9999 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D08 compound treatment 287520.0 -68100.0 -0.46 307590.0 -21600.0 -0.16 -0.4359 -0.8969 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D09 compound treatment 358050.0 2420.0 0.02 252820.0 -76300.0 -0.55 -0.3793 -0.6859 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D10 compound treatment 226570.0 -129000.0 -0.87 152480.0 -177000.0 -1.28 -1.5211 -0.9826 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D11 mock treatment 357120.0 1490.0 0.01 427870.0 98700.0 0.71 0.5123 0.717 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D12 mock treatment 299690.0 -55900.0 -0.38 285500.0 -43700.0 -0.32 -0.4908 -0.9961 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D13 compound treatment 319950.0 -35700.0 -0.24 297410.0 -31800.0 -0.23 -0.3331 -0.9997 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D14 compound treatment 345330.0 -10300.0 -0.07 327850.0 -1320.0 -0.01 -0.056 -0.7967 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D15 mock treatment 306130.0 -49500.0 -0.33 416760.0 87600.0 0.63 0.2118 0.2955 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D16 mock treatment 336370.0 -19300.0 -0.13 419400.0 90200.0 0.65 0.3698 0.5553 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D17 compound treatment 361060.0 5430.0 0.04 365290.0 36100.0 0.26 0.2108 0.7985 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D18 compound treatment 428450.0 72800.0 0.49 385410.0 56200.0 0.41 0.6358 0.9956 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D19 compound treatment 356720.0 1090.0 0.01 357710.0 28500.0 0.21 0.1513 0.7318 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D20 compound treatment 337640.0 -18000.0 -0.12 400640.0 71500.0 0.52 0.2799 0.5266 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D21 compound treatment 241570.0 -114000.0 -0.77 272900.0 -56300.0 -0.41 -0.833 -0.9556 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D22 compound treatment 367400.0 11800.0 0.08 301920.0 -27200.0 -0.2 -0.0833 -0.3915 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D23 compound treatment 280730.0 -74900.0 -0.51 314620.0 -14500.0 -0.11 -0.4323 -0.8363 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 D24 compound treatment 263270.0 -92400.0 -0.62 265870.0 -63300.0 -0.46 -0.7653 -0.9885 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E01 mock treatment 424880.0 69200.0 0.47 377030.0 47900.0 0.35 0.5758 0.9891 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E02 mock treatment 281760.0 -73900.0 -0.5 339420.0 10300.0 0.07 -0.3005 -0.5954 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E03 compound treatment 302180.0 -53500.0 -0.36 315570.0 -13600.0 -0.1 -0.325 -0.8682 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E04 compound treatment 302370.0 -53300.0 -0.36 360420.0 31300.0 0.23 -0.0945 -0.2224 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E05 compound treatment 375360.0 19700.0 0.13 349710.0 20500.0 0.15 0.1994 0.9985 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E06 compound treatment 294510.0 -61100.0 -0.41 261440.0 -67700.0 -0.49 -0.6387 -0.9964 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E07 compound treatment 240040.0 -116000.0 -0.78 256160.0 -73000.0 -0.53 -0.926 -0.9819 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E08 compound treatment 320660.0 -35000.0 -0.24 284820.0 -44300.0 -0.32 -0.3941 -0.9886 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E09 mock treatment 468880.0 113000.0 0.77 433160.0 104000.0 0.75 1.0734 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E10 mock treatment 453560.0 97900.0 0.66 339540.0 10400.0 0.08 0.521 0.7823 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E11 compound treatment 390080.0 34400.0 0.23 300400.0 -28800.0 -0.21 0.0173 0.0554 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E12 compound treatment 206320.0 -149000.0 -1.01 195200.0 -134000.0 -0.97 -1.3991 -0.9998 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E13 compound treatment 277650.0 -78000.0 -0.53 268920.0 -60200.0 -0.44 -0.681 -0.9956 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E14 compound treatment 378560.0 22900.0 0.15 408230.0 79100.0 0.57 0.5142 0.8673 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E15 compound treatment 347530.0 -8100.0 -0.05 320260.0 -8910.0 -0.06 -0.0843 -0.9967 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E16 compound treatment 390630.0 35000.0 0.24 363260.0 34100.0 0.25 0.3417 0.9998 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E17 mock treatment 404770.0 49100.0 0.33 402940.0 73800.0 0.53 0.6124 0.9739 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E18 mock treatment 438090.0 82500.0 0.56 372510.0 43300.0 0.31 0.6158 0.9631 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E19 compound treatment 180320.0 -175000.0 -1.18 175360.0 -154000.0 -1.11 -1.6249 -0.9995 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E20 compound treatment 338780.0 -16900.0 -0.11 329310.0 140.0 0.0 -0.0798 -0.7008 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E21 compound treatment 329960.0 -25700.0 -0.17 330880.0 1710.0 0.01 -0.1139 -0.655 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E22 compound treatment 325660.0 -30000.0 -0.2 301290.0 -27900.0 -0.2 -0.2859 -1.0 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E23 compound treatment 264160.0 -91500.0 -0.62 259220.0 -69900.0 -0.51 -0.7951 -0.9951 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 E24 compound treatment 267490.0 -88100.0 -0.6 289920.0 -39200.0 -0.28 -0.622 -0.9427 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F01 mock treatment 353880.0 -1750.0 -0.01 351930.0 22800.0 0.16 0.1081 0.6546 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F02 mock treatment 411550.0 55900.0 0.38 307710.0 -21500.0 -0.16 0.1573 0.3851 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F03 compound treatment 265030.0 -90600.0 -0.61 337680.0 8510.0 0.06 -0.3893 -0.6328 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F04 compound treatment 396560.0 40900.0 0.28 355430.0 26300.0 0.19 0.33 0.9833 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F05 compound treatment 181760.0 -174000.0 -1.17 268710.0 -60500.0 -0.44 -1.1402 -0.9095 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F06 compound treatment 273020.0 -82600.0 -0.56 430400.0 101000.0 0.73 0.1235 0.134 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F07 compound treatment 238850.0 -117000.0 -0.79 357850.0 28700.0 0.21 -0.4112 -0.5039 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F08 compound treatment 247520.0 -108000.0 -0.73 282350.0 -46800.0 -0.34 -0.7562 -0.939 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F09 mock treatment 342160.0 -13500.0 -0.09 383740.0 54600.0 0.4 0.215 0.5303 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F10 mock treatment 381080.0 25400.0 0.17 341370.0 12200.0 0.09 0.184 0.9521 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F11 compound treatment 383520.0 27900.0 0.19 401370.0 72200.0 0.52 0.5028 0.905 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F12 compound treatment 367780.0 12100.0 0.08 363300.0 34100.0 0.25 0.2327 0.894 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F13 compound treatment 396480.0 40800.0 0.28 385170.0 56000.0 0.41 0.4818 0.9824 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F14 compound treatment 310400.0 -45200.0 -0.31 292700.0 -36500.0 -0.26 -0.4028 -0.9973 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F15 compound treatment 273950.0 -81700.0 -0.55 198880.0 -130000.0 -0.94 -1.0572 -0.9674 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F16 compound treatment 260360.0 -95300.0 -0.64 229450.0 -99700.0 -0.72 -0.9656 -0.9984 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F17 mock treatment 371770.0 16100.0 0.11 354290.0 25100.0 0.18 0.2057 0.9701 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F18 mock treatment 474830.0 119000.0 0.81 326450.0 -2720.0 -0.02 0.5556 0.6896 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F19 compound treatment 180650.0 -175000.0 -1.18 171330.0 -158000.0 -1.14 -1.644 -0.9999 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F20 compound treatment 425870.0 70200.0 0.47 339490.0 10300.0 0.07 0.3884 0.8085 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F21 compound treatment 314990.0 -40600.0 -0.27 341060.0 11900.0 0.09 -0.1333 -0.4633 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F22 compound treatment 349290.0 -6340.0 -0.04 364430.0 35300.0 0.26 0.1502 0.5803 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F23 compound treatment 99460.0 -256000.0 -1.73 85140.0 -244000.0 -1.77 -2.4731 -0.9999 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 F24 compound treatment 286350.0 -69300.0 -0.47 292160.0 -37000.0 -0.27 -0.5205 -0.9649 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G01 compound treatment 104000.0 -252000.0 -1.7 86280.0 -243000.0 -1.76 -2.4455 -0.9999 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G02 compound treatment 261860.0 -93800.0 -0.63 240180.0 -89000.0 -0.64 -0.9035 -1.0 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G03 mock treatment 384090.0 28500.0 0.19 420800.0 91600.0 0.66 0.605 0.876 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G04 mock treatment 446970.0 91300.0 0.62 265310.0 -63900.0 -0.46 0.1095 0.142 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G05 compound treatment 389280.0 33600.0 0.23 323290.0 -5880.0 -0.04 0.1307 0.5649 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G06 compound treatment 188250.0 -167000.0 -1.13 145600.0 -184000.0 -1.33 -1.7394 -0.9968 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G07 compound treatment 225170.0 -130000.0 -0.88 185140.0 -144000.0 -1.04 -1.3606 -0.9965 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G08 compound treatment 212490.0 -143000.0 -0.97 218680.0 -110000.0 -0.8 -1.2495 -0.9955 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G09 compound treatment 410560.0 54900.0 0.37 319410.0 -9760.0 -0.07 0.2125 0.5624 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G10 compound treatment 399200.0 43600.0 0.29 402310.0 73100.0 0.53 0.5825 0.9616 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G11 compound treatment 73080.0 -283000.0 -1.91 35580.0 -294000.0 -2.13 -2.8528 -0.9986 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G12 compound treatment 196670.0 -159000.0 -1.07 260270.0 -68900.0 -0.5 -1.1122 -0.9391 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G13 compound treatment 449120.0 93500.0 0.63 281010.0 -48200.0 -0.35 0.2001 0.2774 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G14 compound treatment 357020.0 1390.0 0.01 321220.0 -7950.0 -0.06 -0.0341 -0.5843 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G15 compound treatment 453600.0 98000.0 0.66 402310.0 73100.0 0.53 0.8425 0.9939 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G16 compound treatment 282970.0 -72700.0 -0.49 269150.0 -60000.0 -0.43 -0.6544 -0.9981 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G17 compound treatment 142240.0 -213000.0 -1.44 160080.0 -169000.0 -1.22 -1.8851 -0.9967 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G18 compound treatment 269760.0 -85900.0 -0.58 280420.0 -48700.0 -0.35 -0.6598 -0.9716 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G19 mock treatment 379070.0 23400.0 0.16 379360.0 50200.0 0.36 0.3689 0.9307 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G20 mock treatment 382580.0 26900.0 0.18 399590.0 70400.0 0.51 0.4892 0.9038 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G21 compound treatment 281980.0 -73700.0 -0.5 217540.0 -112000.0 -0.81 -0.9233 -0.9729 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G22 compound treatment 451320.0 95700.0 0.65 365670.0 36500.0 0.26 0.644 0.9221 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G23 compound treatment 275090.0 -80500.0 -0.54 231710.0 -97500.0 -0.71 -0.8837 -0.9918 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 G24 compound treatment 261210.0 -94400.0 -0.64 287580.0 -41600.0 -0.3 -0.664 -0.9412 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H01 compound treatment 286190.0 -69400.0 -0.47 200800.0 -128000.0 -0.93 -0.9889 -0.9499 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H02 compound treatment 271330.0 -84300.0 -0.57 320090.0 -9080.0 -0.07 -0.4493 -0.7835 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H03 mock treatment 353050.0 -2580.0 -0.02 278170.0 -51000.0 -0.37 -0.2734 -0.7397 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H04 mock treatment 489290.0 134000.0 0.9 448250.0 119000.0 0.86 1.2481 0.9997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H05 compound treatment 338080.0 -17600.0 -0.12 265280.0 -63900.0 -0.46 -0.4109 -0.8606 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H06 compound treatment 280820.0 -74800.0 -0.51 295900.0 -33300.0 -0.24 -0.5277 -0.9425 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H07 compound treatment 354730.0 -903.0 -0.01 321490.0 -7680.0 -0.06 -0.0436 -0.78 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H08 compound treatment 445130.0 89500.0 0.6 238420.0 -90700.0 -0.66 -0.0369 -0.0414 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H09 compound treatment 312870.0 -42800.0 -0.29 352320.0 23200.0 0.17 -0.0858 -0.2569 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H10 compound treatment 424870.0 69200.0 0.47 315680.0 -13500.0 -0.1 0.2618 0.5477 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H11 compound treatment 387790.0 32200.0 0.22 229940.0 -99200.0 -0.72 -0.3543 -0.4721 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H12 compound treatment 249000.0 -107000.0 -0.72 199960.0 -129000.0 -0.94 -1.1709 -0.9917 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H13 compound treatment 385370.0 29700.0 0.2 433450.0 104000.0 0.75 0.6759 0.8652 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H14 compound treatment 292810.0 -62800.0 -0.42 244530.0 -84600.0 -0.61 -0.7334 -0.9839 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H15 compound treatment 342510.0 -13100.0 -0.09 383230.0 54100.0 0.39 0.214 0.5334 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H16 compound treatment 258820.0 -96800.0 -0.65 251790.0 -77400.0 -0.56 -0.8586 -0.997 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H17 compound treatment 330740.0 -24900.0 -0.17 300240.0 -28900.0 -0.21 -0.267 -0.9941 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H18 compound treatment 380020.0 24400.0 0.16 256480.0 -72700.0 -0.53 -0.2556 -0.4635 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H19 mock treatment 394810.0 39200.0 0.26 353500.0 24300.0 0.18 0.3117 0.9804 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H20 mock treatment 302080.0 -53600.0 -0.36 306960.0 -22200.0 -0.16 -0.3696 -0.9333 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H21 compound treatment 283920.0 -71700.0 -0.48 411360.0 82200.0 0.59 0.0781 0.1018 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H22 compound treatment 283920.0 -71700.0 -0.48 262370.0 -66800.0 -0.48 -0.6846 -1.0 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H23 compound treatment 213600.0 -142000.0 -0.96 290170.0 -39000.0 -0.28 -0.8782 -0.8779 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 H24 compound treatment 310750.0 -44900.0 -0.3 273320.0 -55800.0 -0.4 -0.5003 -0.99 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I01 compound treatment 121700.0 -234000.0 -1.58 155360.0 -174000.0 -1.26 -2.0074 -0.9936 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I02 compound treatment 273560.0 -82100.0 -0.55 164890.0 -164000.0 -1.19 -1.233 -0.9397 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I03 compound treatment 182190.0 -173000.0 -1.17 181480.0 -148000.0 -1.07 -1.5847 -0.9989 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I04 compound treatment 231170.0 -124000.0 -0.84 292810.0 -36400.0 -0.26 -0.7808 -0.886 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I05 mock treatment 241210.0 -114000.0 -0.77 316240.0 -12900.0 -0.09 -0.6129 -0.787 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I06 mock treatment 453620.0 98000.0 0.66 401400.0 72200.0 0.52 0.8379 0.9932 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I07 compound treatment 441710.0 86100.0 0.58 275110.0 -54100.0 -0.39 0.1345 0.1919 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I08 compound treatment 372920.0 17300.0 0.12 435760.0 107000.0 0.77 0.6282 0.805 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I09 compound treatment 262400.0 -93200.0 -0.63 293840.0 -35300.0 -0.26 -0.6263 -0.9212 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I10 compound treatment 364240.0 8610.0 0.06 299770.0 -29400.0 -0.21 -0.1094 -0.4957 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I11 compound treatment 365050.0 9420.0 0.06 249550.0 -79600.0 -0.58 -0.3626 -0.6252 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I12 compound treatment 279000.0 -76600.0 -0.52 343970.0 14800.0 0.11 -0.2904 -0.5492 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I13 compound treatment 430780.0 75100.0 0.51 312850.0 -16300.0 -0.12 0.2755 0.5285 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I14 compound treatment 203060.0 -153000.0 -1.03 199060.0 -130000.0 -0.94 -1.395 -0.999 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I15 compound treatment 196710.0 -159000.0 -1.07 61700.0 -267000.0 -1.94 -2.1284 -0.9613 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I16 compound treatment 211250.0 -144000.0 -0.98 249920.0 -79200.0 -0.57 -1.0955 -0.968 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I17 compound treatment 285210.0 -70400.0 -0.48 385180.0 56000.0 0.41 -0.0498 -0.0796 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I18 compound treatment 228320.0 -127000.0 -0.86 214950.0 -114000.0 -0.83 -1.1929 -0.9998 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I19 compound treatment 343700.0 -11900.0 -0.08 243200.0 -86000.0 -0.62 -0.4971 -0.7921 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I20 compound treatment 435970.0 80300.0 0.54 295730.0 -33400.0 -0.24 0.2127 0.3578 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I21 mock treatment 364720.0 9090.0 0.06 258720.0 -70400.0 -0.51 -0.3172 -0.6175 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I22 mock treatment 349720.0 -5910.0 -0.04 281330.0 -47800.0 -0.35 -0.2731 -0.7835 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I23 compound treatment 241070.0 -115000.0 -0.77 239680.0 -89500.0 -0.65 -1.0054 -0.9961 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 I24 compound treatment 293600.0 -62000.0 -0.42 281000.0 -48200.0 -0.35 -0.5429 -0.9958 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J01 compound treatment 260990.0 -94600.0 -0.64 221610.0 -108000.0 -0.78 -1.0028 -0.9952 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J02 compound treatment 342480.0 -13200.0 -0.09 173160.0 -156000.0 -1.13 -0.8614 -0.7604 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J03 compound treatment 191710.0 -164000.0 -1.11 177650.0 -152000.0 -1.1 -1.5588 -1.0 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J04 compound treatment 209290.0 -146000.0 -0.99 294080.0 -35100.0 -0.25 -0.8788 -0.8608 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J05 mock treatment 247640.0 -108000.0 -0.73 172160.0 -157000.0 -1.14 -1.3197 -0.977 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J06 mock treatment 208690.0 -147000.0 -0.99 233440.0 -95700.0 -0.69 -1.1921 -0.9845 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J07 compound treatment 234610.0 -121000.0 -0.82 303200.0 -26000.0 -0.19 -0.7112 -0.8476 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J08 compound treatment 254090.0 -102000.0 -0.69 196570.0 -133000.0 -0.96 -1.1639 -0.9864 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J09 compound treatment 347850.0 -7780.0 -0.05 422080.0 92900.0 0.67 0.4384 0.6498 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J10 compound treatment 235440.0 -120000.0 -0.81 416870.0 87700.0 0.63 -0.1253 -0.1216 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J11 compound treatment 402900.0 47300.0 0.32 321220.0 -7950.0 -0.06 0.1851 0.5705 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J12 compound treatment 116210.0 -239000.0 -1.62 169620.0 -160000.0 -1.15 -1.9606 -0.9864 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J13 compound treatment 228220.0 -127000.0 -0.86 297830.0 -31300.0 -0.23 -0.7692 -0.8639 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J14 compound treatment 201970.0 -154000.0 -1.04 284770.0 -44400.0 -0.32 -0.9614 -0.8846 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J15 compound treatment 185250.0 -170000.0 -1.15 154560.0 -175000.0 -1.26 -1.7078 -0.9989 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J16 compound treatment 359960.0 4330.0 0.03 153880.0 -175000.0 -1.27 -0.8766 -0.6906 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J17 compound treatment 207360.0 -148000.0 -1.0 358280.0 29100.0 0.21 -0.5594 -0.5464 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J18 compound treatment 226800.0 -129000.0 -0.87 224680.0 -104000.0 -0.76 -1.1504 -0.9975 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J19 compound treatment 219850.0 -136000.0 -0.92 210200.0 -119000.0 -0.86 -1.2577 -0.9995 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J20 compound treatment 375380.0 19700.0 0.13 410480.0 81300.0 0.59 0.5106 0.8459 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J21 mock treatment 325830.0 -29800.0 -0.2 390260.0 61100.0 0.44 0.1703 0.3505 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J22 mock treatment 282910.0 -72700.0 -0.49 285120.0 -44000.0 -0.32 -0.5729 -0.9781 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J23 compound treatment 208160.0 -147000.0 -1.0 182400.0 -147000.0 -1.06 -1.4559 -0.9995 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 J24 compound treatment 278000.0 -77600.0 -0.52 292320.0 -36800.0 -0.27 -0.5595 -0.9508 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K01 compound treatment 426410.0 70800.0 0.48 458080.0 129000.0 0.93 0.998 0.9518 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K02 compound treatment 382590.0 27000.0 0.18 387650.0 58500.0 0.42 0.4281 0.929 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K03 compound treatment 170460.0 -185000.0 -1.25 274790.0 -54400.0 -0.39 -1.1631 -0.8867 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K04 compound treatment 258160.0 -97500.0 -0.66 228890.0 -100000.0 -0.73 -0.979 -0.9988 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K05 compound treatment 60290.0 -295000.0 -2.0 82300.0 -247000.0 -1.79 -2.6747 -0.9985 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K06 compound treatment 288870.0 -66800.0 -0.45 443040.0 114000.0 0.82 0.2639 0.2808 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K07 mock treatment 264080.0 -91600.0 -0.62 417760.0 88600.0 0.64 0.016 0.018 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K08 mock treatment 274270.0 -81400.0 -0.55 229720.0 -99400.0 -0.72 -0.8978 -0.9911 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K09 compound treatment 253840.0 -102000.0 -0.69 159360.0 -170000.0 -1.23 -1.3556 -0.9624 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K10 compound treatment 475200.0 120000.0 0.81 240050.0 -89100.0 -0.65 0.1151 0.1113 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K11 compound treatment 109380.0 -246000.0 -1.66 136820.0 -192000.0 -1.39 -2.1611 -0.9961 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K12 compound treatment 286880.0 -68800.0 -0.46 238790.0 -90400.0 -0.65 -0.7911 -0.9859 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K13 compound treatment 376870.0 21200.0 0.14 340240.0 11100.0 0.08 0.1581 0.9621 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K14 compound treatment 266490.0 -89100.0 -0.6 230890.0 -98300.0 -0.71 -0.929 -0.9966 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K15 mock treatment 477210.0 122000.0 0.82 271580.0 -57600.0 -0.42 0.2861 0.3106 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K16 mock treatment 492320.0 137000.0 0.92 359070.0 29900.0 0.22 0.8061 0.8498 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K17 compound treatment 412720.0 57100.0 0.39 362410.0 33200.0 0.24 0.4429 0.9742 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K18 compound treatment 318010.0 -37600.0 -0.25 278560.0 -50600.0 -0.37 -0.4388 -0.9841 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K19 compound treatment 206370.0 -149000.0 -1.01 226940.0 -102000.0 -0.74 -1.2364 -0.9884 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K20 compound treatment 351200.0 -4430.0 -0.03 296010.0 -33200.0 -0.24 -0.1909 -0.7892 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K21 compound treatment 377410.0 21800.0 0.15 275870.0 -53300.0 -0.39 -0.1688 -0.4087 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K22 compound treatment 253560.0 -102000.0 -0.69 182770.0 -146000.0 -1.06 -1.2371 -0.9783 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K23 mock treatment 326240.0 -29400.0 -0.2 336200.0 7030.0 0.05 -0.1044 -0.5095 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 K24 mock treatment 422210.0 66600.0 0.45 275410.0 -53800.0 -0.39 0.0429 0.0721 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L01 compound treatment 188500.0 -167000.0 -1.13 179630.0 -150000.0 -1.08 -1.564 -0.9998 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L02 compound treatment 143290.0 -212000.0 -1.43 244340.0 -84800.0 -0.61 -1.4487 -0.9283 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L03 compound treatment 29450.0 -326000.0 -2.2 112380.0 -217000.0 -1.57 -2.6681 -0.9861 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L04 compound treatment 319810.0 -35800.0 -0.24 215700.0 -113000.0 -0.82 -0.752 -0.8781 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L05 compound treatment 394080.0 38400.0 0.26 224000.0 -105000.0 -0.76 -0.3546 -0.4409 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L06 compound treatment 193140.0 -162000.0 -1.1 217120.0 -112000.0 -0.81 -1.3499 -0.9889 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L07 mock treatment 273480.0 -82200.0 -0.56 284830.0 -44300.0 -0.32 -0.6195 -0.9661 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L08 mock treatment 444580.0 88900.0 0.6 407370.0 78200.0 0.57 0.8253 0.9996 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L09 compound treatment 454600.0 99000.0 0.67 284050.0 -45100.0 -0.33 0.2419 0.325 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L10 compound treatment 343210.0 -12400.0 -0.08 291230.0 -37900.0 -0.27 -0.2536 -0.8829 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L11 compound treatment 124910.0 -231000.0 -1.56 217870.0 -111000.0 -0.81 -1.6721 -0.9528 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L12 compound treatment 214120.0 -142000.0 -0.96 228210.0 -101000.0 -0.73 -1.1929 -0.9912 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L13 compound treatment 303120.0 -52500.0 -0.35 248800.0 -80400.0 -0.58 -0.6623 -0.9719 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L14 compound treatment 471950.0 116000.0 0.79 389980.0 60800.0 0.44 0.867 0.9625 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L15 mock treatment 237180.0 -118000.0 -0.8 209280.0 -120000.0 -0.87 -1.1796 -0.9992 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L16 mock treatment 391680.0 36000.0 0.24 333440.0 4270.0 0.03 0.1941 0.7905 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L17 compound treatment 400480.0 44800.0 0.3 387710.0 58500.0 0.42 0.5139 0.9865 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L18 compound treatment 252960.0 -103000.0 -0.69 358740.0 29600.0 0.21 -0.3392 -0.4672 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L19 compound treatment 277920.0 -77700.0 -0.53 305660.0 -23500.0 -0.17 -0.4916 -0.8907 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L20 compound treatment 357300.0 1670.0 0.01 323360.0 -5810.0 -0.04 -0.0218 -0.5001 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L21 compound treatment 354470.0 -1160.0 -0.01 324900.0 -4270.0 -0.03 -0.0274 -0.8595 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L22 compound treatment 211070.0 -145000.0 -0.98 241440.0 -87700.0 -0.64 -1.1398 -0.9783 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L23 mock treatment 365180.0 9550.0 0.06 324800.0 -4370.0 -0.03 0.0232 0.3236 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 L24 mock treatment 278270.0 -77400.0 -0.52 327440.0 -1730.0 -0.01 -0.3785 -0.7238 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M01 compound treatment 418600.0 63000.0 0.43 368750.0 39600.0 0.29 0.5034 0.9815 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M02 compound treatment 395680.0 40000.0 0.27 431310.0 102000.0 0.74 0.7142 0.9071 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M03 compound treatment 317180.0 -38500.0 -0.26 324640.0 -4530.0 -0.03 -0.2069 -0.7901 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M04 compound treatment 217180.0 -138000.0 -0.94 192380.0 -137000.0 -0.99 -1.3617 -0.9996 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M05 compound treatment 204700.0 -151000.0 -1.02 246890.0 -82300.0 -0.6 -1.1423 -0.9672 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M06 compound treatment 219860.0 -136000.0 -0.92 402280.0 73100.0 0.53 -0.2745 -0.2591 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M07 compound treatment 289670.0 -66000.0 -0.45 316480.0 -12700.0 -0.09 -0.3801 -0.8353 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M08 compound treatment 307560.0 -48100.0 -0.32 320960.0 -8210.0 -0.06 -0.2717 -0.8228 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M09 mock treatment 453810.0 98200.0 0.66 397720.0 68600.0 0.5 0.82 0.9898 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M10 mock treatment 299910.0 -55700.0 -0.38 310880.0 -18300.0 -0.13 -0.3599 -0.9016 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M11 compound treatment 153410.0 -202000.0 -1.37 163750.0 -165000.0 -1.2 -1.8129 -0.9978 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M12 compound treatment 284890.0 -70700.0 -0.48 240410.0 -88800.0 -0.64 -0.7923 -0.9894 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M13 mock treatment 326450.0 -29200.0 -0.2 204870.0 -124000.0 -0.9 -0.7757 -0.8421 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M14 mock treatment 456820.0 101000.0 0.68 347430.0 18300.0 0.13 0.5769 0.8285 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M15 compound treatment 492980.0 137000.0 0.93 300740.0 -28400.0 -0.21 0.5107 0.5372 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M16 compound treatment 484560.0 129000.0 0.87 348290.0 19100.0 0.14 0.7139 0.8093 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M17 compound treatment 302430.0 -53200.0 -0.36 273660.0 -55500.0 -0.4 -0.5383 -0.9985 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M18 compound treatment 448770.0 93100.0 0.63 357770.0 28600.0 0.21 0.5914 0.8927 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M19 compound treatment 285690.0 -69900.0 -0.47 400810.0 71600.0 0.52 0.0325 0.0464 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M20 compound treatment 316700.0 -38900.0 -0.26 302100.0 -27100.0 -0.2 -0.3246 -0.9895 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M21 compound treatment 350820.0 -4810.0 -0.03 250830.0 -78300.0 -0.57 -0.424 -0.7464 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M22 compound treatment 251210.0 -104000.0 -0.71 228990.0 -100000.0 -0.73 -1.0117 -0.9999 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M23 compound treatment 311440.0 -44200.0 -0.3 273230.0 -55900.0 -0.4 -0.4975 -0.9888 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 M24 compound treatment 284320.0 -71300.0 -0.48 283010.0 -46200.0 -0.33 -0.577 -0.984 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N01 compound treatment 176010.0 -180000.0 -1.21 347750.0 18600.0 0.13 -0.7631 -0.6249 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N02 compound treatment 208800.0 -147000.0 -0.99 303310.0 -25900.0 -0.19 -0.8339 -0.826 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N03 compound treatment 255890.0 -99700.0 -0.67 244260.0 -84900.0 -0.61 -0.9112 -0.9989 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N04 compound treatment 293130.0 -62500.0 -0.42 165300.0 -164000.0 -1.19 -1.1374 -0.9033 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N05 compound treatment 390400.0 34800.0 0.23 395910.0 66700.0 0.48 0.5077 0.9451 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N06 compound treatment 233150.0 -122000.0 -0.83 321730.0 -7440.0 -0.05 -0.6233 -0.7515 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N07 compound treatment 436960.0 81300.0 0.55 284400.0 -44800.0 -0.32 0.1594 0.2499 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N08 compound treatment 229500.0 -126000.0 -0.85 245840.0 -83300.0 -0.6 -1.0292 -0.9857 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N09 mock treatment 376570.0 20900.0 0.14 367710.0 38500.0 0.28 0.2973 0.9505 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N10 mock treatment 218420.0 -137000.0 -0.93 304920.0 -24200.0 -0.18 -0.7797 -0.8263 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N11 compound treatment 366430.0 10800.0 0.07 321070.0 -8100.0 -0.06 0.0101 0.1082 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N12 compound treatment 251110.0 -105000.0 -0.71 261790.0 -67400.0 -0.49 -0.8443 -0.9837 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N13 mock treatment 263470.0 -92200.0 -0.62 249920.0 -79200.0 -0.57 -0.846 -0.9992 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N14 mock treatment 336320.0 -19300.0 -0.13 429700.0 101000.0 0.73 0.4223 0.5712 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N15 compound treatment 361050.0 5420.0 0.04 440710.0 112000.0 0.81 0.5968 0.7384 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N16 compound treatment 226340.0 -129000.0 -0.87 307810.0 -21400.0 -0.15 -0.7271 -0.8195 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N17 compound treatment 279360.0 -76300.0 -0.52 354090.0 24900.0 0.18 -0.2369 -0.4338 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N18 compound treatment 150600.0 -205000.0 -1.39 127070.0 -202000.0 -1.46 -2.0141 -0.9996 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N19 compound treatment 260000.0 -95600.0 -0.65 175610.0 -154000.0 -1.11 -1.2429 -0.9667 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N20 compound treatment 244760.0 -111000.0 -0.75 240690.0 -88500.0 -0.64 -0.9826 -0.997 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N21 compound treatment 344260.0 -11400.0 -0.08 357610.0 28400.0 0.21 0.0912 0.4152 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N22 compound treatment 129380.0 -226000.0 -1.53 128050.0 -201000.0 -1.46 -2.1105 -0.9997 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N23 compound treatment 314260.0 -41400.0 -0.28 321410.0 -7760.0 -0.06 -0.2374 -0.8325 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 N24 compound treatment 181540.0 -174000.0 -1.18 91480.0 -238000.0 -1.72 -2.0484 -0.9828 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O01 compound treatment 247620.0 -108000.0 -0.73 289710.0 -39500.0 -0.29 -0.718 -0.9162 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O02 compound treatment 309040.0 -46600.0 -0.31 346120.0 17000.0 0.12 -0.1358 -0.4021 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O03 compound treatment 274240.0 -81400.0 -0.55 227760.0 -101000.0 -0.73 -0.908 -0.9899 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O04 compound treatment 181320.0 -174000.0 -1.18 220870.0 -108000.0 -0.78 -1.3872 -0.9804 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O05 compound treatment 337810.0 -17800.0 -0.12 234560.0 -94600.0 -0.68 -0.5694 -0.8189 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O06 compound treatment 330840.0 -24800.0 -0.17 374130.0 45000.0 0.33 0.1117 0.3051 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O07 compound treatment 283540.0 -72100.0 -0.49 225850.0 -103000.0 -0.75 -0.8733 -0.9784 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O08 compound treatment 174000.0 -182000.0 -1.23 155640.0 -174000.0 -1.26 -1.7561 -0.9999 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O09 compound treatment 224740.0 -131000.0 -0.88 218470.0 -111000.0 -0.8 -1.192 -0.9988 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O10 compound treatment 345440.0 -10200.0 -0.07 264520.0 -64600.0 -0.47 -0.3796 -0.8025 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O11 mock treatment 280120.0 -75500.0 -0.51 327200.0 -1970.0 -0.01 -0.3709 -0.7266 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O12 mock treatment 333990.0 -21600.0 -0.15 271710.0 -57500.0 -0.42 -0.3975 -0.9016 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O13 compound treatment 342270.0 -13400.0 -0.09 271680.0 -57500.0 -0.42 -0.3581 -0.841 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O14 compound treatment 254520.0 -101000.0 -0.68 222720.0 -106000.0 -0.77 -1.028 -0.9982 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O15 compound treatment 348830.0 -6800.0 -0.05 316840.0 -12300.0 -0.09 -0.0956 -0.9524 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O16 compound treatment 259400.0 -96200.0 -0.65 322150.0 -7020.0 -0.05 -0.4957 -0.76 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O17 compound treatment 294300.0 -61300.0 -0.41 247520.0 -81600.0 -0.59 -0.711 -0.9849 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O18 compound treatment 237070.0 -119000.0 -0.8 299650.0 -29500.0 -0.21 -0.7176 -0.8655 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O19 compound treatment 187100.0 -169000.0 -1.14 152540.0 -177000.0 -1.28 -1.7093 -0.9983 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O20 compound treatment 191000.0 -165000.0 -1.11 245770.0 -83400.0 -0.6 -1.2135 -0.9588 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O21 compound treatment 260500.0 -95100.0 -0.64 185440.0 -144000.0 -1.04 -1.1902 -0.9732 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O22 compound treatment 219200.0 -136000.0 -0.92 188640.0 -141000.0 -1.02 -1.3712 -0.9988 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O23 compound treatment 342600.0 -13000.0 -0.09 324690.0 -4480.0 -0.03 -0.0852 -0.9079 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 O24 compound treatment 214660.0 -141000.0 -0.95 221380.0 -108000.0 -0.78 -1.2253 -0.9951 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P01 compound treatment 88840.0 -267000.0 -1.8 227230.0 -102000.0 -0.74 -1.7965 -0.9223 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P02 compound treatment 43010.0 -313000.0 -2.11 37520.0 -292000.0 -2.11 -2.9865 -1.0 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P03 compound treatment 154770.0 -201000.0 -1.36 197870.0 -131000.0 -0.95 -1.6318 -0.9848 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P04 compound treatment 173970.0 -182000.0 -1.23 166770.0 -162000.0 -1.18 -1.6992 -0.9998 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P05 compound treatment 200900.0 -155000.0 -1.05 224750.0 -104000.0 -0.76 -1.2738 -0.9873 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P06 compound treatment 153460.0 -202000.0 -1.37 247410.0 -81800.0 -0.59 -1.3844 -0.9299 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P07 compound treatment 190650.0 -165000.0 -1.11 266190.0 -63000.0 -0.46 -1.1106 -0.9222 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P08 compound treatment 179040.0 -177000.0 -1.19 156660.0 -173000.0 -1.25 -1.7268 -0.9997 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P09 compound treatment 186940.0 -169000.0 -1.14 184500.0 -145000.0 -1.05 -1.5465 -0.9991 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P10 compound treatment 141820.0 -214000.0 -1.44 157880.0 -171000.0 -1.24 -1.8983 -0.9971 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P11 mock treatment 222880.0 -133000.0 -0.9 202780.0 -126000.0 -0.91 -1.2812 -1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P12 mock treatment 261810.0 -93800.0 -0.63 200660.0 -129000.0 -0.93 -1.1061 -0.9825 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P13 compound treatment 189800.0 -166000.0 -1.12 222120.0 -107000.0 -0.77 -1.3403 -0.9838 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P14 compound treatment 245010.0 -111000.0 -0.75 208520.0 -121000.0 -0.87 -1.1461 -0.997 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P15 compound treatment 213600.0 -142000.0 -0.96 196730.0 -132000.0 -0.96 -1.3565 -1.0 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P16 compound treatment 233520.0 -122000.0 -0.83 232320.0 -96800.0 -0.7 -1.0792 -0.9967 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P17 compound treatment 244800.0 -111000.0 -0.75 273130.0 -56000.0 -0.41 -0.8164 -0.9585 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P18 compound treatment 148020.0 -208000.0 -1.4 194640.0 -135000.0 -0.97 -1.6806 -0.9841 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P19 compound treatment 291850.0 -63800.0 -0.43 295750.0 -33400.0 -0.24 -0.4758 -0.9627 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P20 compound treatment 203610.0 -152000.0 -1.03 173660.0 -156000.0 -1.13 -1.5223 -0.999 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P21 compound treatment 210510.0 -145000.0 -0.98 203960.0 -125000.0 -0.91 -1.3343 -0.9992 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P22 compound treatment 228570.0 -127000.0 -0.86 199200.0 -130000.0 -0.94 -1.2724 -0.999 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P23 compound treatment 212520.0 -143000.0 -0.97 205400.0 -124000.0 -0.9 -1.3173 -0.9993 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2098 P24 compound treatment 176390.0 -179000.0 -1.21 211270.0 -118000.0 -0.85 -1.4599 -0.9853 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A01 compound treatment 336890.0 10800.0 0.07 303750.0 -27500.0 -0.2 -0.0889 -0.4199 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A02 compound treatment 358100.0 32000.0 0.22 398370.0 67200.0 0.49 0.4967 0.9335 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A03 compound treatment 325460.0 -619.0 0.0 405540.0 74300.0 0.54 0.3775 0.7016 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A04 compound treatment 363370.0 37300.0 0.25 164000.0 -167000.0 -1.21 -0.6778 -0.5482 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A05 compound treatment 280070.0 -46000.0 -0.31 374190.0 43000.0 0.31 1.0E-4 3.0E-4 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A06 compound treatment 297060.0 -29000.0 -0.2 304040.0 -27200.0 -0.2 -0.2778 -1.0 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A07 compound treatment 238820.0 -87300.0 -0.59 242500.0 -88700.0 -0.64 -0.871 -0.9991 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A08 compound treatment 281600.0 -44500.0 -0.3 298240.0 -33000.0 -0.24 -0.3813 -0.9935 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A09 compound treatment 313050.0 -13000.0 -0.09 262910.0 -68300.0 -0.49 -0.4119 -0.8201 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A10 compound treatment 313410.0 -12700.0 -0.09 200830.0 -130000.0 -0.94 -0.7279 -0.7681 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A11 compound treatment 333130.0 7050.0 0.05 288540.0 -42700.0 -0.31 -0.1848 -0.5911 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A12 compound treatment 248600.0 -77500.0 -0.52 316770.0 -14400.0 -0.1 -0.4441 -0.8319 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A13 mock treatment 215390.0 -111000.0 -0.75 297630.0 -33600.0 -0.24 -0.7008 -0.8911 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A14 mock treatment 340220.0 14100.0 0.1 271940.0 -59300.0 -0.43 -0.2359 -0.5365 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A15 compound treatment 373960.0 47900.0 0.32 371680.0 40500.0 0.29 0.4359 0.9988 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A16 compound treatment 299150.0 -26900.0 -0.18 225540.0 -106000.0 -0.76 -0.6696 -0.8515 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A17 compound treatment 271170.0 -54900.0 -0.37 378810.0 47600.0 0.34 -0.0187 -0.037 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A18 compound treatment 202040.0 -124000.0 -0.84 325720.0 -5500.0 -0.04 -0.6208 -0.7399 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A19 compound treatment 270130.0 -55900.0 -0.38 277840.0 -53400.0 -0.39 -0.5405 -0.9999 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A20 compound treatment 249950.0 -76100.0 -0.51 296680.0 -34500.0 -0.25 -0.5405 -0.9451 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A21 compound treatment 275680.0 -50400.0 -0.34 333570.0 2350.0 0.02 -0.2288 -0.6709 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A22 compound treatment 296440.0 -29600.0 -0.2 296340.0 -34900.0 -0.25 -0.3201 -0.9934 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A23 compound treatment 275450.0 -50600.0 -0.34 301850.0 -29400.0 -0.21 -0.3922 -0.9738 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 A24 compound treatment 236350.0 -89700.0 -0.61 343240.0 12000.0 0.09 -0.3672 -0.5995 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B01 compound treatment 411440.0 85400.0 0.58 293560.0 -37700.0 -0.27 0.2151 0.3371 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B02 compound treatment 427910.0 102000.0 0.69 392890.0 61700.0 0.45 0.8022 0.9781 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B03 compound treatment 436960.0 111000.0 0.75 345050.0 13800.0 0.1 0.6006 0.7945 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B04 compound treatment 392030.0 66000.0 0.45 331300.0 82.0 0.0 0.3155 0.708 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B05 compound treatment 444510.0 118000.0 0.8 372800.0 41600.0 0.3 0.7787 0.9108 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B06 compound treatment 445920.0 120000.0 0.81 307370.0 -23800.0 -0.17 0.4505 0.5441 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B07 compound treatment 407810.0 81700.0 0.55 429880.0 98700.0 0.71 0.8955 0.9919 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B08 compound treatment 408850.0 82800.0 0.56 270080.0 -61100.0 -0.44 0.0825 0.1157 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B09 compound treatment 382080.0 56000.0 0.38 376850.0 45600.0 0.33 0.5011 0.9977 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B10 compound treatment 399960.0 73900.0 0.5 408920.0 77700.0 0.56 0.7507 0.9982 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B11 compound treatment 449120.0 123000.0 0.83 334560.0 3340.0 0.02 0.605 0.7274 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B12 compound treatment 350650.0 24600.0 0.17 426360.0 95100.0 0.69 0.6044 0.8531 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B13 mock treatment 385810.0 59700.0 0.4 367200.0 36000.0 0.26 0.4696 0.9776 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B14 mock treatment 388420.0 62300.0 0.42 394780.0 63600.0 0.46 0.6232 0.999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B15 compound treatment 331440.0 5360.0 0.04 336660.0 5440.0 0.04 0.0535 0.9991 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B16 compound treatment 360480.0 34400.0 0.23 422100.0 90900.0 0.66 0.6296 0.9023 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B17 compound treatment 350850.0 24800.0 0.17 325490.0 -5730.0 -0.04 0.089 0.5163 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B18 compound treatment 373340.0 47300.0 0.32 372290.0 41100.0 0.3 0.436 0.9994 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B19 compound treatment 463200.0 137000.0 0.93 411540.0 80300.0 0.58 1.0663 0.9748 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B20 compound treatment 317080.0 -9000.0 -0.06 399420.0 68200.0 0.49 0.3061 0.6154 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B21 compound treatment 442800.0 117000.0 0.79 394570.0 63400.0 0.46 0.882 0.9667 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B22 compound treatment 389400.0 63300.0 0.43 313210.0 -18000.0 -0.13 0.2104 0.4703 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B23 compound treatment 360680.0 34600.0 0.23 407470.0 76300.0 0.55 0.5556 0.9269 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 B24 compound treatment 366370.0 40300.0 0.27 339400.0 8180.0 0.06 0.2344 0.8413 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C01 compound treatment 318310.0 -7770.0 -0.05 344840.0 13600.0 0.1 0.0326 0.2919 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C02 compound treatment 350680.0 24600.0 0.17 323010.0 -8210.0 -0.06 0.0755 0.4278 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C03 compound treatment 395170.0 69100.0 0.47 286050.0 -45200.0 -0.33 0.0989 0.1735 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C04 compound treatment 379720.0 53600.0 0.36 335810.0 4590.0 0.03 0.2798 0.7687 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C05 compound treatment 317440.0 -8640.0 -0.06 218810.0 -112000.0 -0.81 -0.6167 -0.7559 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C06 compound treatment 333500.0 7420.0 0.05 264030.0 -67200.0 -0.49 -0.3085 -0.6309 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C07 compound treatment 339940.0 13900.0 0.09 225990.0 -105000.0 -0.76 -0.4724 -0.6155 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C08 compound treatment 338040.0 12000.0 0.08 320930.0 -10300.0 -0.07 0.0045 0.0408 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C09 compound treatment 334760.0 8680.0 0.06 349410.0 18200.0 0.13 0.1346 0.9336 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C10 compound treatment 333130.0 7050.0 0.05 339930.0 8710.0 0.06 0.0783 0.9904 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C11 mock treatment 283930.0 -42100.0 -0.28 329890.0 -1330.0 -0.01 -0.2082 -0.7306 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C12 mock treatment 243040.0 -83000.0 -0.56 324440.0 -6780.0 -0.05 -0.4314 -0.766 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C13 compound treatment 374560.0 48500.0 0.33 399690.0 68500.0 0.5 0.5821 0.9798 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C14 compound treatment 272160.0 -53900.0 -0.36 359600.0 28400.0 0.21 -0.1123 -0.2686 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C15 mock treatment 384160.0 58100.0 0.39 285470.0 -45700.0 -0.33 0.0433 0.0844 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C16 mock treatment 305950.0 -20100.0 -0.14 323380.0 -7840.0 -0.06 -0.1363 -0.9248 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C17 compound treatment 305320.0 -20800.0 -0.14 338320.0 7100.0 0.05 -0.0628 -0.4206 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C18 compound treatment 342110.0 16000.0 0.11 377920.0 46700.0 0.34 0.3156 0.8891 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C19 compound treatment 337520.0 11400.0 0.08 317330.0 -13900.0 -0.1 -0.0164 -0.1295 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C20 compound treatment 279730.0 -46300.0 -0.31 297840.0 -33400.0 -0.24 -0.3923 -0.9918 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C21 compound treatment 344280.0 18200.0 0.12 303400.0 -27800.0 -0.2 -0.0554 -0.2349 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C22 compound treatment 294800.0 -31300.0 -0.21 298450.0 -32800.0 -0.24 -0.3172 -0.9983 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C23 compound treatment 290200.0 -35900.0 -0.24 383750.0 52500.0 0.38 0.0975 0.2161 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 C24 compound treatment 244100.0 -82000.0 -0.55 341090.0 9870.0 0.07 -0.3411 -0.6108 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D01 compound treatment 405470.0 79400.0 0.54 340510.0 9290.0 0.07 0.4269 0.7896 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D02 compound treatment 366720.0 40600.0 0.27 283450.0 -47800.0 -0.35 -0.0503 -0.114 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D03 compound treatment 413300.0 87200.0 0.59 260250.0 -71000.0 -0.51 0.0535 0.0684 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D04 compound treatment 308740.0 -17300.0 -0.12 301520.0 -29700.0 -0.21 -0.2349 -0.9593 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D05 compound treatment 448560.0 122000.0 0.83 196900.0 -134000.0 -0.97 -0.1023 -0.0802 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D06 compound treatment 400510.0 74400.0 0.5 381310.0 50100.0 0.36 0.612 0.9871 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D07 compound treatment 252220.0 -73900.0 -0.5 367540.0 36300.0 0.26 -0.167 -0.296 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D08 compound treatment 298310.0 -27800.0 -0.19 460340.0 129000.0 0.93 0.5283 0.5541 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D09 compound treatment 439590.0 114000.0 0.77 316840.0 -14400.0 -0.1 0.4687 0.6056 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D10 compound treatment 382830.0 56800.0 0.38 357600.0 26400.0 0.19 0.4062 0.9482 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D11 mock treatment 321160.0 -4920.0 -0.03 442460.0 111000.0 0.81 0.5459 0.6773 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D12 mock treatment 302880.0 -23200.0 -0.16 343520.0 12300.0 0.09 -0.0479 -0.2655 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D13 compound treatment 399890.0 73800.0 0.5 415000.0 83800.0 0.61 0.7815 0.9953 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D14 compound treatment 297660.0 -28400.0 -0.19 330460.0 -758.0 -0.01 -0.1397 -0.727 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D15 mock treatment 349730.0 23700.0 0.16 419010.0 87800.0 0.64 0.5624 0.8582 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D16 mock treatment 420000.0 93900.0 0.63 344640.0 13400.0 0.1 0.5174 0.806 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D17 compound treatment 272540.0 -53500.0 -0.36 337760.0 6540.0 0.05 -0.2223 -0.6093 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D18 compound treatment 305210.0 -20900.0 -0.14 386150.0 54900.0 0.4 0.1815 0.4301 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D19 compound treatment 346050.0 20000.0 0.13 357480.0 26300.0 0.19 0.2298 0.9859 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D20 compound treatment 350810.0 24700.0 0.17 329660.0 -1560.0 -0.01 0.1102 0.6579 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D21 compound treatment 305150.0 -20900.0 -0.14 347160.0 15900.0 0.12 -0.0184 -0.1008 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D22 compound treatment 339890.0 13800.0 0.09 305920.0 -25300.0 -0.18 -0.0635 -0.309 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D23 compound treatment 353300.0 27200.0 0.18 404120.0 72900.0 0.53 0.5032 0.9004 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 D24 compound treatment 330730.0 4650.0 0.03 326800.0 -4420.0 -0.03 -4.0E-4 -0.0087 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E01 mock treatment 349840.0 23800.0 0.16 420120.0 88900.0 0.64 0.5686 0.8572 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E02 mock treatment 402240.0 76200.0 0.51 376870.0 45700.0 0.33 0.5976 0.9771 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E03 compound treatment 417760.0 91700.0 0.62 371900.0 40700.0 0.29 0.6463 0.9422 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E04 compound treatment 320320.0 -5760.0 -0.04 404190.0 73000.0 0.53 0.346 0.6533 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E05 compound treatment 402990.0 76900.0 0.52 287760.0 -43500.0 -0.31 0.145 0.2387 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E06 compound treatment 447260.0 121000.0 0.82 412820.0 81600.0 0.59 0.9967 0.9872 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E07 compound treatment 254190.0 -71900.0 -0.49 356600.0 25400.0 0.18 -0.2135 -0.4112 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E08 compound treatment 360290.0 34200.0 0.23 420000.0 88800.0 0.64 0.6179 0.9047 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E09 mock treatment 339520.0 13400.0 0.09 478080.0 147000.0 1.06 0.816 0.7647 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E10 mock treatment 420710.0 94600.0 0.64 439950.0 109000.0 0.79 1.0087 0.9947 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E11 compound treatment 307560.0 -18500.0 -0.13 286460.0 -44800.0 -0.32 -0.3176 -0.9144 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E12 compound treatment 394910.0 68800.0 0.47 270680.0 -60500.0 -0.44 0.019 0.0297 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E13 compound treatment 435450.0 109000.0 0.74 345390.0 14200.0 0.1 0.5951 0.7976 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E14 compound treatment 330340.0 4260.0 0.03 394240.0 63000.0 0.46 0.343 0.7502 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E15 compound treatment 284670.0 -41400.0 -0.28 435590.0 104000.0 0.76 0.3364 0.4175 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E16 compound treatment 333460.0 7380.0 0.05 385650.0 54400.0 0.39 0.3139 0.7903 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E17 mock treatment 325760.0 -319.0 0.0 347170.0 16000.0 0.12 0.0801 0.6938 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E18 mock treatment 325340.0 -739.0 0.0 337970.0 6750.0 0.05 0.031 0.6316 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E19 compound treatment 287050.0 -39000.0 -0.26 228920.0 -102000.0 -0.74 -0.7101 -0.9033 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E20 compound treatment 339490.0 13400.0 0.09 397240.0 66000.0 0.48 0.402 0.8265 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E21 compound treatment 379050.0 53000.0 0.36 358900.0 27700.0 0.2 0.3948 0.9624 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E22 compound treatment 348230.0 22200.0 0.15 339470.0 8250.0 0.06 0.1481 0.9188 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E23 compound treatment 318400.0 -7680.0 -0.05 355930.0 24700.0 0.18 0.0898 0.4822 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 E24 compound treatment 313160.0 -12900.0 -0.09 373020.0 41800.0 0.3 0.1522 0.4834 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F01 mock treatment 331700.0 5620.0 0.04 400320.0 69100.0 0.5 0.3806 0.7586 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F02 mock treatment 409770.0 83700.0 0.57 252800.0 -78400.0 -0.57 -0.0015 -0.0019 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F03 compound treatment 368510.0 42400.0 0.29 357300.0 26100.0 0.19 0.3362 0.9795 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F04 compound treatment 317880.0 -8200.0 -0.06 348360.0 17100.0 0.12 0.0486 0.3574 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F05 compound treatment 474500.0 148000.0 1.0 321320.0 -9900.0 -0.07 0.6585 0.6549 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F06 compound treatment 254010.0 -72100.0 -0.49 214200.0 -117000.0 -0.85 -0.9433 -0.9654 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F07 compound treatment 331520.0 5440.0 0.04 296590.0 -34600.0 -0.25 -0.1513 -0.597 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F08 compound treatment 241760.0 -84300.0 -0.57 411430.0 80200.0 0.58 0.0077 0.0095 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F09 mock treatment 461200.0 135000.0 0.91 347720.0 16500.0 0.12 0.7301 0.7929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F10 mock treatment 442080.0 116000.0 0.78 362530.0 31300.0 0.23 0.7145 0.8757 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F11 compound treatment 257390.0 -68700.0 -0.46 287730.0 -43500.0 -0.31 -0.5508 -0.9821 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F12 compound treatment 273020.0 -53100.0 -0.36 242460.0 -88800.0 -0.64 -0.7078 -0.962 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F13 compound treatment 288380.0 -37700.0 -0.25 429120.0 97900.0 0.71 0.321 0.4263 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F14 compound treatment 351630.0 25600.0 0.17 410990.0 79800.0 0.58 0.5304 0.88 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F15 compound treatment 385830.0 59800.0 0.4 299120.0 -32100.0 -0.23 0.1212 0.2601 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F16 compound treatment 390340.0 64300.0 0.43 318880.0 -12300.0 -0.09 0.2439 0.5501 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F17 mock treatment 273780.0 -52300.0 -0.35 301850.0 -29400.0 -0.21 -0.4002 -0.9704 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F18 mock treatment 367540.0 41500.0 0.28 374470.0 43300.0 0.31 0.4195 0.9985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F19 compound treatment 339610.0 13500.0 0.09 354630.0 23400.0 0.17 0.1845 0.9581 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F20 compound treatment 299100.0 -27000.0 -0.18 274930.0 -56300.0 -0.41 -0.417 -0.9342 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F21 compound treatment 265180.0 -60900.0 -0.41 338240.0 7020.0 0.05 -0.255 -0.6151 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F22 compound treatment 322210.0 -3870.0 -0.03 330260.0 -958.0 -0.01 -0.0234 -0.8648 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F23 compound treatment 258680.0 -67400.0 -0.46 326720.0 -4500.0 -0.03 -0.345 -0.7557 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 F24 compound treatment 275080.0 -51000.0 -0.34 294500.0 -36700.0 -0.27 -0.4316 -0.9918 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G01 compound treatment 322640.0 -3440.0 -0.02 381040.0 49800.0 0.36 0.2386 0.6602 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G02 compound treatment 379420.0 53300.0 0.36 405280.0 74100.0 0.54 0.634 0.9813 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G03 mock treatment 360050.0 34000.0 0.23 330400.0 -818.0 -0.01 0.1581 0.6886 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G04 mock treatment 302660.0 -23400.0 -0.16 293370.0 -37800.0 -0.27 -0.3056 -0.966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G05 compound treatment 282980.0 -43100.0 -0.29 427200.0 96000.0 0.69 0.2854 0.3788 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G06 compound treatment 389790.0 63700.0 0.43 269020.0 -62200.0 -0.45 -0.014 -0.0224 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G07 compound treatment 425470.0 99400.0 0.67 267520.0 -63700.0 -0.46 0.1488 0.1827 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G08 compound treatment 392960.0 66900.0 0.45 336010.0 4790.0 0.03 0.3441 0.7592 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G09 compound treatment 412980.0 86900.0 0.59 349440.0 18200.0 0.13 0.5085 0.8449 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G10 compound treatment 451780.0 126000.0 0.85 402410.0 71200.0 0.52 0.965 0.9713 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G11 compound treatment 354250.0 28200.0 0.19 497380.0 166000.0 1.2 0.9851 0.8089 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G12 compound treatment 253560.0 -72500.0 -0.49 246580.0 -84600.0 -0.61 -0.7797 -0.9939 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G13 compound treatment 358320.0 32200.0 0.22 380280.0 49100.0 0.36 0.4052 0.9725 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G14 compound treatment 270830.0 -55200.0 -0.37 371390.0 40200.0 0.29 -0.0583 -0.1233 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G15 compound treatment 310400.0 -15700.0 -0.11 303420.0 -27800.0 -0.2 -0.2172 -0.9551 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G16 compound treatment 346590.0 20500.0 0.14 423050.0 91800.0 0.66 0.5681 0.8365 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G17 compound treatment 363910.0 37800.0 0.26 278630.0 -52600.0 -0.38 -0.0884 -0.1929 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G18 compound treatment 346660.0 20600.0 0.14 354400.0 23200.0 0.17 0.217 0.9956 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G19 mock treatment 340380.0 14300.0 0.1 362510.0 31300.0 0.23 0.2285 0.9279 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G20 mock treatment 332760.0 6680.0 0.05 372750.0 41500.0 0.3 0.2445 0.8043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G21 compound treatment 365310.0 39200.0 0.27 347310.0 16100.0 0.12 0.2698 0.9318 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G22 compound treatment 312380.0 -13700.0 -0.09 346560.0 15300.0 0.11 0.0131 0.0905 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G23 compound treatment 272400.0 -53700.0 -0.36 354090.0 22900.0 0.17 -0.1394 -0.3496 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 G24 compound treatment 321250.0 -4830.0 -0.03 357220.0 26000.0 0.19 0.11 0.5759 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H01 compound treatment 217360.0 -109000.0 -0.73 260030.0 -71200.0 -0.52 -0.8838 -0.985 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H02 compound treatment 291170.0 -34900.0 -0.24 256800.0 -74400.0 -0.54 -0.5477 -0.9313 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H03 mock treatment 306110.0 -20000.0 -0.13 245660.0 -85600.0 -0.62 -0.5334 -0.8414 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H04 mock treatment 363200.0 37100.0 0.25 438960.0 108000.0 0.78 0.7289 0.8896 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H05 compound treatment 267200.0 -58900.0 -0.4 255760.0 -75500.0 -0.55 -0.6676 -0.9879 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H06 compound treatment 415310.0 89200.0 0.6 406110.0 74900.0 0.54 0.8097 0.9986 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H07 compound treatment 337120.0 11000.0 0.07 322040.0 -9180.0 -0.07 0.0058 0.0578 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H08 compound treatment 479840.0 154000.0 1.04 343740.0 12500.0 0.09 0.7987 0.7659 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H09 compound treatment 458360.0 132000.0 0.89 247010.0 -84200.0 -0.61 0.201 0.1858 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H10 compound treatment 330760.0 4680.0 0.03 353920.0 22700.0 0.16 0.1386 0.828 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H11 compound treatment 313030.0 -13000.0 -0.09 205790.0 -125000.0 -0.91 -0.7044 -0.7721 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H12 compound treatment 300120.0 -26000.0 -0.18 190190.0 -141000.0 -1.02 -0.8459 -0.8166 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H13 compound treatment 319100.0 -6980.0 -0.05 383130.0 51900.0 0.38 0.2324 0.6136 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H14 compound treatment 367040.0 41000.0 0.28 373610.0 42400.0 0.31 0.4127 0.9987 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H15 compound treatment 318030.0 -8050.0 -0.05 381280.0 50100.0 0.36 0.2178 0.5943 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H16 compound treatment 375520.0 49400.0 0.33 405840.0 74600.0 0.54 0.6182 0.9733 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H17 compound treatment 324000.0 -2080.0 -0.01 313240.0 -18000.0 -0.13 -0.102 -0.7789 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H18 compound treatment 382650.0 56600.0 0.38 332760.0 1540.0 0.01 0.2782 0.7274 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H19 mock treatment 307040.0 -19000.0 -0.13 385080.0 53900.0 0.39 0.1847 0.45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H20 mock treatment 318110.0 -7970.0 -0.05 339570.0 8350.0 0.06 0.0047 0.0578 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H21 compound treatment 361600.0 35500.0 0.24 430680.0 99500.0 0.72 0.6788 0.8944 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H22 compound treatment 276320.0 -49800.0 -0.34 370660.0 39400.0 0.29 -0.0358 -0.0813 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H23 compound treatment 268900.0 -57200.0 -0.39 482040.0 151000.0 1.09 0.4988 0.4307 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 H24 compound treatment 259530.0 -66500.0 -0.45 344070.0 12900.0 0.09 -0.2522 -0.5492 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I01 compound treatment 415070.0 89000.0 0.6 320440.0 -10800.0 -0.08 0.37 0.6102 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I02 compound treatment 224330.0 -102000.0 -0.69 399270.0 68100.0 0.49 -0.1378 -0.1629 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I03 compound treatment 335750.0 9670.0 0.07 315070.0 -16100.0 -0.12 -0.0364 -0.2722 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I04 compound treatment 422910.0 96800.0 0.65 242090.0 -89100.0 -0.65 0.0064 0.007 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I05 mock treatment 258090.0 -68000.0 -0.46 348660.0 17400.0 0.13 -0.2356 -0.4944 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I06 mock treatment 239310.0 -86800.0 -0.59 290440.0 -40800.0 -0.3 -0.6233 -0.9496 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I07 compound treatment 352000.0 25900.0 0.18 276420.0 -54800.0 -0.4 -0.1566 -0.3613 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I08 compound treatment 229230.0 -96800.0 -0.65 271610.0 -59600.0 -0.43 -0.7678 -0.9796 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I09 compound treatment 274460.0 -51600.0 -0.35 325010.0 -6210.0 -0.04 -0.2784 -0.7917 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I10 compound treatment 332720.0 6640.0 0.04 267160.0 -64100.0 -0.46 -0.2962 -0.6357 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I11 compound treatment 279000.0 -47100.0 -0.32 423960.0 92700.0 0.67 0.2498 0.3362 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I12 compound treatment 364320.0 38200.0 0.26 277730.0 -53500.0 -0.39 -0.0911 -0.1957 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I13 compound treatment 312280.0 -13800.0 -0.09 230010.0 -101000.0 -0.73 -0.584 -0.7907 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I14 compound treatment 432330.0 106000.0 0.72 417440.0 86200.0 0.62 0.949 0.9976 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I15 compound treatment 336120.0 10000.0 0.07 441210.0 110000.0 0.8 0.611 0.7646 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I16 compound treatment 402150.0 76100.0 0.51 293530.0 -37700.0 -0.27 0.1705 0.2931 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I17 compound treatment 370900.0 44800.0 0.3 269480.0 -61700.0 -0.45 -0.1019 -0.1887 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I18 compound treatment 351900.0 25800.0 0.17 491380.0 160000.0 1.16 0.9432 0.8045 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I19 compound treatment 273280.0 -52800.0 -0.36 338580.0 7360.0 0.05 -0.2146 -0.5949 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I20 compound treatment 314620.0 -11500.0 -0.08 292510.0 -38700.0 -0.28 -0.2529 -0.8699 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I21 mock treatment 305400.0 -20700.0 -0.14 303480.0 -27700.0 -0.2 -0.2408 -0.9843 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I22 mock treatment 290130.0 -35900.0 -0.24 247970.0 -83200.0 -0.6 -0.5979 -0.9202 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I23 compound treatment 326430.0 351.0 0.0 351520.0 20300.0 0.15 0.1056 0.7184 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 I24 compound treatment 247910.0 -78200.0 -0.53 328880.0 -2340.0 -0.02 -0.3854 -0.7294 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J01 compound treatment 397440.0 71400.0 0.48 242180.0 -89000.0 -0.64 -0.1148 -0.1426 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J02 compound treatment 201660.0 -124000.0 -0.84 209830.0 -121000.0 -0.88 -1.2158 -0.9998 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J03 compound treatment 229820.0 -96300.0 -0.65 214450.0 -117000.0 -0.85 -1.0576 -0.9916 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J04 compound treatment 220750.0 -105000.0 -0.71 255700.0 -75500.0 -0.55 -0.8898 -0.9915 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J05 mock treatment 274020.0 -52100.0 -0.35 209640.0 -122000.0 -0.88 -0.871 -0.919 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J06 mock treatment 406100.0 80000.0 0.54 206080.0 -125000.0 -0.91 -0.2582 -0.2448 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J07 compound treatment 322880.0 -3200.0 -0.02 335080.0 3860.0 0.03 0.0045 0.1269 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J08 compound treatment 362610.0 36500.0 0.25 218720.0 -112000.0 -0.81 -0.4013 -0.4716 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J09 compound treatment 398240.0 72200.0 0.49 393470.0 62300.0 0.45 0.6634 0.9992 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J10 compound treatment 232500.0 -93600.0 -0.63 410400.0 79200.0 0.57 -0.0418 -0.049 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J11 compound treatment 266850.0 -59200.0 -0.4 235800.0 -95400.0 -0.69 -0.7714 -0.9663 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J12 compound treatment 236570.0 -89500.0 -0.6 401170.0 70000.0 0.51 -0.0696 -0.0882 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J13 compound treatment 380420.0 54300.0 0.37 432510.0 101000.0 0.73 0.7781 0.9489 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J14 compound treatment 367090.0 41000.0 0.28 372510.0 41300.0 0.3 0.4073 0.9993 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J15 compound treatment 441920.0 116000.0 0.78 380990.0 49800.0 0.36 0.8082 0.938 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J16 compound treatment 389120.0 63000.0 0.43 394560.0 63300.0 0.46 0.6254 0.9993 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J17 compound treatment 293810.0 -32300.0 -0.22 336680.0 5460.0 0.04 -0.1262 -0.5696 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J18 compound treatment 295320.0 -30800.0 -0.21 320560.0 -10700.0 -0.08 -0.2015 -0.909 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J19 compound treatment 236920.0 -89200.0 -0.6 406310.0 75100.0 0.54 -0.0416 -0.0513 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J20 compound treatment 291360.0 -34700.0 -0.23 422970.0 91800.0 0.66 0.3038 0.4313 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J21 mock treatment 306150.0 -19900.0 -0.13 356880.0 25700.0 0.19 0.0361 0.1575 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J22 mock treatment 340700.0 14600.0 0.1 355200.0 24000.0 0.17 0.1926 0.9643 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J23 compound treatment 290030.0 -36000.0 -0.24 285550.0 -45700.0 -0.33 -0.406 -0.9887 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 J24 compound treatment 227910.0 -98200.0 -0.66 292480.0 -38700.0 -0.28 -0.6673 -0.9266 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K01 compound treatment 332030.0 5950.0 0.04 269500.0 -61700.0 -0.45 -0.2875 -0.6409 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K02 compound treatment 419690.0 93600.0 0.63 335230.0 4010.0 0.03 0.4678 0.7388 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K03 compound treatment 497890.0 172000.0 1.16 385280.0 54100.0 0.39 1.0976 0.8959 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K04 compound treatment 205470.0 -121000.0 -0.81 339200.0 7980.0 0.06 -0.5354 -0.6553 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K05 compound treatment 243110.0 -83000.0 -0.56 182560.0 -149000.0 -1.08 -1.1573 -0.9538 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K06 compound treatment 142830.0 -183000.0 -1.24 247600.0 -83600.0 -0.61 -1.3035 -0.9458 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K07 mock treatment 430950.0 105000.0 0.71 217290.0 -114000.0 -0.82 -0.0821 -0.0755 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K08 mock treatment 230810.0 -95300.0 -0.64 385890.0 54700.0 0.4 -0.1753 -0.232 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K09 compound treatment 247850.0 -78200.0 -0.53 193350.0 -138000.0 -1.0 -1.0795 -0.9558 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K10 compound treatment 209780.0 -116000.0 -0.79 169230.0 -162000.0 -1.17 -1.3848 -0.981 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K11 compound treatment 404260.0 78200.0 0.53 335140.0 3920.0 0.03 0.3936 0.744 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K12 compound treatment 200800.0 -125000.0 -0.85 266600.0 -64600.0 -0.47 -0.9293 -0.9609 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K13 compound treatment 299650.0 -26400.0 -0.18 466020.0 135000.0 0.98 0.5637 0.5683 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K14 compound treatment 468090.0 142000.0 0.96 475770.0 145000.0 1.05 1.4184 0.9991 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K15 mock treatment 417010.0 90900.0 0.61 368020.0 36800.0 0.27 0.6228 0.93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K16 mock treatment 281920.0 -44200.0 -0.3 259100.0 -72100.0 -0.52 -0.5801 -0.9648 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K17 compound treatment 357620.0 31500.0 0.21 324250.0 -6970.0 -0.05 0.115 0.5252 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K18 compound treatment 320210.0 -5870.0 -0.04 327840.0 -3380.0 -0.02 -0.0453 -0.973 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K19 compound treatment 345970.0 19900.0 0.13 327440.0 -3780.0 -0.03 0.0757 0.5519 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K20 compound treatment 407060.0 81000.0 0.55 335420.0 4200.0 0.03 0.4084 0.7453 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K21 compound treatment 388100.0 62000.0 0.42 340550.0 9330.0 0.07 0.3441 0.8106 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K22 compound treatment 336930.0 10900.0 0.07 371100.0 39900.0 0.29 0.256 0.8594 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K23 mock treatment 342620.0 16500.0 0.11 525130.0 194000.0 1.4 1.0716 0.761 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 K24 mock treatment 287940.0 -38100.0 -0.26 379800.0 48600.0 0.35 0.0665 0.1524 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L01 compound treatment 306030.0 -20000.0 -0.14 420570.0 89400.0 0.65 0.3616 0.5471 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L02 compound treatment 336240.0 10200.0 0.07 220000.0 -111000.0 -0.81 -0.5207 -0.6445 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L03 compound treatment 274880.0 -51200.0 -0.35 261800.0 -69400.0 -0.5 -0.5999 -0.9834 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L04 compound treatment 194660.0 -131000.0 -0.89 374200.0 43000.0 0.31 -0.4079 -0.4335 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L05 compound treatment 208480.0 -118000.0 -0.79 187220.0 -144000.0 -1.04 -1.2989 -0.991 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L06 compound treatment 360860.0 34800.0 0.24 282660.0 -48600.0 -0.35 -0.0824 -0.1948 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L07 mock treatment 416510.0 90400.0 0.61 207220.0 -124000.0 -0.9 -0.2026 -0.1866 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L08 mock treatment 434830.0 109000.0 0.73 250620.0 -80600.0 -0.58 0.107 0.1141 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L09 compound treatment 245380.0 -80700.0 -0.55 248590.0 -82600.0 -0.6 -0.8085 -0.9989 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L10 compound treatment 272220.0 -53900.0 -0.36 355430.0 24200.0 0.18 -0.1334 -0.3302 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L11 compound treatment 265850.0 -60200.0 -0.41 288740.0 -42500.0 -0.31 -0.5052 -0.9904 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L12 compound treatment 273220.0 -52900.0 -0.36 305940.0 -25300.0 -0.18 -0.3819 -0.9517 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L13 compound treatment 424450.0 98400.0 0.66 227700.0 -104000.0 -0.75 -0.0599 -0.0598 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L14 compound treatment 472600.0 147000.0 0.99 430670.0 99500.0 0.72 1.2091 0.9878 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L15 mock treatment 263310.0 -62800.0 -0.42 280440.0 -50800.0 -0.37 -0.5598 -0.9975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L16 mock treatment 325890.0 -189.0 0.0 263630.0 -67600.0 -0.49 -0.3469 -0.7089 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L17 compound treatment 352260.0 26200.0 0.18 344210.0 13000.0 0.09 0.1916 0.9563 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L18 compound treatment 262490.0 -63600.0 -0.43 247640.0 -83600.0 -0.61 -0.7316 -0.9859 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L19 compound treatment 288180.0 -37900.0 -0.26 386570.0 55400.0 0.4 0.1023 0.215 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L20 compound treatment 350610.0 24500.0 0.17 446630.0 115000.0 0.84 0.708 0.8312 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L21 compound treatment 318270.0 -7810.0 -0.05 369120.0 37900.0 0.27 0.1567 0.5609 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L22 compound treatment 402280.0 76200.0 0.51 364830.0 33600.0 0.24 0.5361 0.9414 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L23 mock treatment 388290.0 62200.0 0.42 356020.0 24800.0 0.18 0.4242 0.928 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 L24 mock treatment 191380.0 -135000.0 -0.91 370660.0 39400.0 0.29 -0.4417 -0.463 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M01 compound treatment 317300.0 -8780.0 -0.06 305810.0 -25400.0 -0.18 -0.172 -0.89 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M02 compound treatment 210780.0 -115000.0 -0.78 250440.0 -80800.0 -0.58 -0.9644 -0.99 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M03 compound treatment 218310.0 -108000.0 -0.73 383860.0 52600.0 0.38 -0.2454 -0.2986 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M04 compound treatment 427910.0 102000.0 0.69 383470.0 52300.0 0.38 0.754 0.9603 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M05 compound treatment 276550.0 -49500.0 -0.33 403390.0 72200.0 0.52 0.1328 0.214 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M06 compound treatment 261020.0 -65100.0 -0.44 480120.0 149000.0 1.08 0.4513 0.3877 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M07 compound treatment 301080.0 -25000.0 -0.17 229820.0 -101000.0 -0.73 -0.6385 -0.8477 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M08 compound treatment 334570.0 8490.0 0.06 235160.0 -96100.0 -0.7 -0.4511 -0.6466 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M09 mock treatment 433820.0 108000.0 0.73 344280.0 13100.0 0.09 0.5816 0.7923 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M10 mock treatment 506080.0 180000.0 1.22 308580.0 -22600.0 -0.16 0.7441 0.6064 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M11 compound treatment 283360.0 -42700.0 -0.29 234400.0 -96800.0 -0.7 -0.6997 -0.9231 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M12 compound treatment 272000.0 -54100.0 -0.37 482130.0 151000.0 1.09 0.5141 0.4463 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M13 mock treatment 233320.0 -92800.0 -0.63 350250.0 19000.0 0.14 -0.3458 -0.5388 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M14 mock treatment 367470.0 41400.0 0.28 312380.0 -18800.0 -0.14 0.1013 0.3257 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M15 compound treatment 373180.0 47100.0 0.32 290200.0 -41000.0 -0.3 0.0151 0.0347 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M16 compound treatment 383970.0 57900.0 0.39 303630.0 -27600.0 -0.2 0.1354 0.3082 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M17 compound treatment 342880.0 16800.0 0.11 334290.0 3070.0 0.02 0.096 0.8299 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M18 compound treatment 424120.0 98000.0 0.66 435370.0 104000.0 0.75 1.0015 0.9979 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M19 compound treatment 347520.0 21400.0 0.14 342520.0 11300.0 0.08 0.1603 0.9634 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M20 compound treatment 407600.0 81500.0 0.55 373570.0 42400.0 0.31 0.6063 0.9617 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M21 compound treatment 344200.0 18100.0 0.12 249380.0 -81800.0 -0.59 -0.3323 -0.5494 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M22 compound treatment 425940.0 99900.0 0.67 293220.0 -38000.0 -0.28 0.2826 0.3879 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M23 compound treatment 400270.0 74200.0 0.5 403860.0 72600.0 0.53 0.7263 0.9997 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 M24 compound treatment 299580.0 -26500.0 -0.18 406720.0 75500.0 0.55 0.2599 0.4518 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N01 compound treatment 366360.0 40300.0 0.27 191460.0 -140000.0 -1.01 -0.5229 -0.4991 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N02 compound treatment 318940.0 -7140.0 -0.05 267450.0 -63800.0 -0.46 -0.3605 -0.7768 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N03 compound treatment 392250.0 66200.0 0.45 280760.0 -50500.0 -0.37 0.0579 0.1002 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N04 compound treatment 305930.0 -20100.0 -0.14 391280.0 60100.0 0.43 0.2112 0.4635 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N05 compound treatment 335110.0 9030.0 0.06 227520.0 -104000.0 -0.75 -0.4876 -0.6475 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N06 compound treatment 280990.0 -45100.0 -0.3 286920.0 -44300.0 -0.32 -0.4422 -0.9997 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N07 compound treatment 300580.0 -25500.0 -0.17 312530.0 -18700.0 -0.14 -0.2175 -0.9928 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N08 compound treatment 290410.0 -35700.0 -0.24 420530.0 89300.0 0.65 0.2867 0.4156 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N09 mock treatment 297350.0 -28700.0 -0.19 364750.0 33500.0 0.24 0.0344 0.1106 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N10 mock treatment 167400.0 -159000.0 -1.07 296010.0 -35200.0 -0.25 -0.9384 -0.8515 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N11 compound treatment 451250.0 125000.0 0.85 410980.0 79800.0 0.58 1.0063 0.9827 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N12 compound treatment 240000.0 -86100.0 -0.58 378720.0 47500.0 0.34 -0.1681 -0.2488 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N13 mock treatment 235540.0 -90500.0 -0.61 371520.0 40300.0 0.29 -0.2263 -0.3339 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N14 mock treatment 301630.0 -24400.0 -0.17 360760.0 29500.0 0.21 0.0344 0.1273 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N15 compound treatment 334400.0 8320.0 0.06 312710.0 -18500.0 -0.13 -0.055 -0.3784 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N16 compound treatment 466000.0 140000.0 0.95 435380.0 104000.0 0.75 1.2017 0.9937 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N17 compound treatment 375970.0 49900.0 0.34 297980.0 -33200.0 -0.24 0.0682 0.1648 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N18 compound treatment 353330.0 27300.0 0.18 302910.0 -28300.0 -0.2 -0.0147 -0.0534 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N19 compound treatment 285800.0 -40300.0 -0.27 369600.0 38400.0 0.28 0.004 0.0103 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N20 compound treatment 327470.0 1390.0 0.01 291060.0 -40200.0 -0.29 -0.1989 -0.6839 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N21 compound treatment 362310.0 36200.0 0.24 304060.0 -27200.0 -0.2 0.0341 0.1086 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N22 compound treatment 385950.0 59900.0 0.4 286830.0 -44400.0 -0.32 0.0588 0.1139 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N23 compound treatment 424450.0 98400.0 0.66 266760.0 -64500.0 -0.47 0.1401 0.1725 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 N24 compound treatment 301170.0 -24900.0 -0.17 247680.0 -83500.0 -0.6 -0.5466 -0.8708 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O01 compound treatment 373230.0 47200.0 0.32 359770.0 28600.0 0.21 0.3714 0.9781 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O02 compound treatment 221340.0 -105000.0 -0.71 339780.0 8560.0 0.06 -0.4566 -0.6427 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O03 compound treatment 209150.0 -117000.0 -0.79 231310.0 -99900.0 -0.72 -1.0701 -0.999 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O04 compound treatment 354410.0 28300.0 0.19 233920.0 -97300.0 -0.7 -0.3627 -0.4969 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O05 compound treatment 387770.0 61700.0 0.42 305200.0 -26000.0 -0.19 0.1616 0.3532 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O06 compound treatment 324320.0 -1760.0 -0.01 263920.0 -67300.0 -0.49 -0.3529 -0.7241 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O07 compound treatment 261710.0 -64400.0 -0.43 320130.0 -11100.0 -0.08 -0.3643 -0.8237 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O08 compound treatment 377600.0 51500.0 0.35 409920.0 78700.0 0.57 0.649 0.9721 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O09 compound treatment 415770.0 89700.0 0.61 334400.0 3180.0 0.02 0.4448 0.7335 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O10 compound treatment 313320.0 -12800.0 -0.09 295680.0 -35500.0 -0.26 -0.2429 -0.8951 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O11 mock treatment 206530.0 -120000.0 -0.81 278200.0 -53000.0 -0.38 -0.8426 -0.9421 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O12 mock treatment 247560.0 -78500.0 -0.53 293920.0 -37300.0 -0.27 -0.5661 -0.9509 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O13 compound treatment 304670.0 -21400.0 -0.14 357180.0 26000.0 0.19 0.0306 0.129 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O14 compound treatment 300270.0 -25800.0 -0.17 310720.0 -20500.0 -0.15 -0.2282 -0.9968 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O15 compound treatment 321720.0 -4360.0 -0.03 348840.0 17600.0 0.13 0.0694 0.5299 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O16 compound treatment 214600.0 -111000.0 -0.75 217120.0 -114000.0 -0.83 -1.1167 -0.9989 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O17 compound treatment 278190.0 -47900.0 -0.32 230290.0 -101000.0 -0.73 -0.7454 -0.9329 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O18 compound treatment 200930.0 -125000.0 -0.85 240000.0 -91200.0 -0.66 -1.0649 -0.9925 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O19 compound treatment 265600.0 -60500.0 -0.41 313490.0 -17700.0 -0.13 -0.3797 -0.8865 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O20 compound treatment 342080.0 16000.0 0.11 324220.0 -7000.0 -0.05 0.0406 0.3403 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O21 compound treatment 426090.0 100000.0 0.68 289940.0 -41300.0 -0.3 0.2665 0.3607 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O22 compound treatment 283520.0 -42600.0 -0.29 294690.0 -36500.0 -0.26 -0.3903 -0.9991 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O23 compound treatment 334080.0 8000.0 0.05 277360.0 -53900.0 -0.39 -0.2375 -0.6033 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 O24 compound treatment 340010.0 13900.0 0.09 232560.0 -98700.0 -0.71 -0.4384 -0.6086 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P01 compound treatment 228320.0 -97800.0 -0.66 211360.0 -120000.0 -0.87 -1.0806 -0.9909 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P02 compound treatment 200800.0 -125000.0 -0.85 206250.0 -125000.0 -0.9 -1.2382 -0.9994 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P03 compound treatment 236340.0 -89700.0 -0.61 197170.0 -134000.0 -0.97 -1.1149 -0.9744 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P04 compound treatment 179840.0 -146000.0 -0.99 171530.0 -160000.0 -1.16 -1.5161 -0.9969 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P05 compound treatment 232560.0 -93500.0 -0.63 171250.0 -160000.0 -1.16 -1.2656 -0.9594 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P06 compound treatment 167070.0 -159000.0 -1.07 174970.0 -156000.0 -1.13 -1.5595 -0.9997 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P07 compound treatment 266050.0 -60000.0 -0.41 227560.0 -104000.0 -0.75 -0.8174 -0.9583 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P08 compound treatment 188610.0 -137000.0 -0.93 203090.0 -128000.0 -0.93 -1.3126 -1.0 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P09 compound treatment 205060.0 -121000.0 -0.82 181570.0 -150000.0 -1.08 -1.3442 -0.9904 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P10 compound treatment 281920.0 -44200.0 -0.3 288670.0 -42500.0 -0.31 -0.4288 -0.9999 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P11 mock treatment 205980.0 -120000.0 -0.81 189090.0 -142000.0 -1.03 -1.3013 -0.9931 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P12 mock treatment 214520.0 -112000.0 -0.75 193530.0 -138000.0 -1.0 -1.2378 -0.9905 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P13 compound treatment 207210.0 -119000.0 -0.8 213700.0 -118000.0 -0.85 -1.1695 -0.9996 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P14 compound treatment 265210.0 -60900.0 -0.41 237690.0 -93500.0 -0.68 -0.7696 -0.9715 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P15 compound treatment 243240.0 -82800.0 -0.56 173320.0 -158000.0 -1.14 -1.204 -0.946 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P16 compound treatment 205640.0 -120000.0 -0.81 200570.0 -131000.0 -0.95 -1.2442 -0.9972 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P17 compound treatment 210210.0 -116000.0 -0.78 190560.0 -141000.0 -1.02 -1.2736 -0.9916 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P18 compound treatment 178090.0 -148000.0 -1.0 211200.0 -120000.0 -0.87 -1.3214 -0.9975 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P19 compound treatment 204910.0 -121000.0 -0.82 202940.0 -128000.0 -0.93 -1.2355 -0.998 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P20 compound treatment 215760.0 -110000.0 -0.75 238630.0 -92600.0 -0.67 -1.001 -0.9986 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P21 compound treatment 173670.0 -152000.0 -1.03 218740.0 -112000.0 -0.81 -1.3039 -0.9932 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P22 compound treatment 235780.0 -90300.0 -0.61 254730.0 -76500.0 -0.55 -0.8229 -0.9988 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P23 compound treatment 242480.0 -83600.0 -0.56 222660.0 -109000.0 -0.79 -0.9551 -0.9869 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2100 P24 compound treatment 197720.0 -128000.0 -0.87 158760.0 -172000.0 -1.25 -1.496 -0.9842 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A01 compound treatment 342790.0 51600.0 0.35 286880.0 -7320.0 -0.05 0.209 0.5929 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A02 compound treatment 184570.0 -107000.0 -0.72 257440.0 -36800.0 -0.27 -0.6976 -0.9083 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A03 compound treatment 214470.0 -76700.0 -0.52 279850.0 -14300.0 -0.1 -0.44 -0.8322 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A04 compound treatment 205340.0 -85900.0 -0.58 340670.0 46500.0 0.34 -0.1723 -0.257 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A05 compound treatment 229030.0 -62200.0 -0.42 348010.0 53800.0 0.39 -0.0216 -0.0377 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A06 compound treatment 153480.0 -138000.0 -0.93 216000.0 -78200.0 -0.57 -1.0583 -0.9716 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A07 compound treatment 217890.0 -73300.0 -0.5 250930.0 -43300.0 -0.31 -0.5717 -0.9756 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A08 compound treatment 304800.0 13600.0 0.09 242950.0 -51200.0 -0.37 -0.1973 -0.5163 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A09 compound treatment 244480.0 -46700.0 -0.32 219170.0 -75000.0 -0.54 -0.6073 -0.9667 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A10 compound treatment 211920.0 -79300.0 -0.54 299550.0 5350.0 0.04 -0.3514 -0.6542 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A11 compound treatment 136560.0 -155000.0 -1.04 300660.0 6460.0 0.05 -0.7057 -0.6748 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A12 compound treatment 234890.0 -56300.0 -0.38 315110.0 20900.0 0.15 -0.162 -0.3956 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A13 mock treatment 262100.0 -29100.0 -0.2 301650.0 7450.0 0.05 -0.1009 -0.4948 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A14 mock treatment 197940.0 -93300.0 -0.63 231680.0 -62500.0 -0.45 -0.7656 -0.9868 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A15 compound treatment 136180.0 -155000.0 -1.05 317600.0 23400.0 0.17 -0.6209 -0.5851 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A16 compound treatment 187680.0 -104000.0 -0.7 258500.0 -35700.0 -0.26 -0.6773 -0.9083 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A17 compound treatment 259360.0 -31800.0 -0.22 272840.0 -21400.0 -0.15 -0.2614 -0.9869 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A18 compound treatment 248120.0 -43100.0 -0.29 311200.0 17000.0 0.12 -0.1188 -0.3759 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A19 compound treatment 261450.0 -29700.0 -0.2 249790.0 -44400.0 -0.32 -0.3694 -0.9744 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A20 compound treatment 195680.0 -95500.0 -0.65 277600.0 -16600.0 -0.12 -0.5413 -0.8246 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A21 compound treatment 258140.0 -33100.0 -0.22 241210.0 -53000.0 -0.38 -0.4292 -0.9669 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A22 compound treatment 275120.0 -16100.0 -0.11 148810.0 -145000.0 -1.05 -0.821 -0.776 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A23 compound treatment 244330.0 -46900.0 -0.32 325930.0 31700.0 0.23 -0.0615 -0.1572 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 A24 compound treatment 283690.0 -7510.0 -0.05 243890.0 -50300.0 -0.36 -0.2934 -0.7979 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B01 compound treatment 213250.0 -77900.0 -0.53 330430.0 36200.0 0.26 -0.187 -0.3177 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B02 compound treatment 231840.0 -59400.0 -0.4 366300.0 72100.0 0.52 0.0855 0.1298 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B03 compound treatment 222560.0 -68600.0 -0.46 330350.0 36200.0 0.26 -0.1429 -0.2683 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B04 compound treatment 275460.0 -15700.0 -0.11 329860.0 35700.0 0.26 0.1074 0.3845 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B05 compound treatment 361850.0 70700.0 0.48 268240.0 -26000.0 -0.19 0.2047 0.399 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B06 compound treatment 278640.0 -12600.0 -0.08 324320.0 30100.0 0.22 0.0942 0.4025 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B07 compound treatment 381440.0 90200.0 0.61 325160.0 31000.0 0.22 0.5896 0.9077 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B08 compound treatment 382740.0 91500.0 0.62 330680.0 36500.0 0.26 0.6241 0.928 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B09 compound treatment 295540.0 4340.0 0.03 347040.0 52800.0 0.38 0.2912 0.7591 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B10 compound treatment 302100.0 10900.0 0.07 326340.0 32100.0 0.23 0.2166 0.8876 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B11 compound treatment 392060.0 101000.0 0.68 394510.0 100000.0 0.73 0.9954 0.9995 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B12 compound treatment 184000.0 -107000.0 -0.72 248800.0 -45400.0 -0.33 -0.7445 -0.9361 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B13 mock treatment 277500.0 -13700.0 -0.09 287200.0 -7000.0 -0.05 -0.1013 -0.9598 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B14 mock treatment 270250.0 -20900.0 -0.14 398720.0 105000.0 0.76 0.4349 0.565 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B15 compound treatment 245730.0 -45500.0 -0.31 387040.0 92800.0 0.67 0.258 0.3491 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B16 compound treatment 354040.0 62800.0 0.42 313240.0 19000.0 0.14 0.3977 0.8909 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B17 compound treatment 288610.0 -2590.0 -0.02 335800.0 41600.0 0.3 0.2006 0.6649 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B18 compound treatment 458960.0 168000.0 1.13 354980.0 60800.0 0.44 1.1127 0.9151 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B19 compound treatment 352420.0 61200.0 0.41 272220.0 -22000.0 -0.16 0.18 0.4062 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B20 compound treatment 393500.0 102000.0 0.69 345540.0 51300.0 0.37 0.7516 0.9577 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B21 compound treatment 253640.0 -37600.0 -0.25 317050.0 22900.0 0.17 -0.0625 -0.2062 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B22 compound treatment 377600.0 86400.0 0.58 329550.0 35400.0 0.26 0.5938 0.9315 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B23 compound treatment 334690.0 43500.0 0.29 300280.0 6080.0 0.04 0.2389 0.8041 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 B24 compound treatment 384160.0 93000.0 0.63 270880.0 -23300.0 -0.17 0.3248 0.4994 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C01 compound treatment 405540.0 114000.0 0.77 331920.0 37700.0 0.27 0.7394 0.9023 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C02 compound treatment 368350.0 77200.0 0.52 278880.0 -15300.0 -0.11 0.2902 0.5445 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C03 compound treatment 298240.0 7040.0 0.05 312430.0 18200.0 0.13 0.127 0.905 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C04 compound treatment 272000.0 -19200.0 -0.13 344130.0 49900.0 0.36 0.1639 0.4267 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C05 compound treatment 234430.0 -56800.0 -0.38 244920.0 -49300.0 -0.36 -0.5235 -0.9993 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C06 compound treatment 241190.0 -50000.0 -0.34 201160.0 -93000.0 -0.67 -0.7152 -0.9491 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C07 compound treatment 217980.0 -73200.0 -0.49 257890.0 -36300.0 -0.26 -0.5357 -0.9562 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C08 compound treatment 269190.0 -22000.0 -0.15 335200.0 41000.0 0.3 0.1047 0.3155 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C09 compound treatment 261360.0 -29800.0 -0.2 283230.0 -11000.0 -0.08 -0.1987 -0.917 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C10 compound treatment 245140.0 -46100.0 -0.31 292290.0 -1910.0 -0.01 -0.2298 -0.7378 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C11 mock treatment 308750.0 17600.0 0.12 257560.0 -36600.0 -0.27 -0.1037 -0.3569 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C12 mock treatment 380160.0 89000.0 0.6 285840.0 -8360.0 -0.06 0.3823 0.6327 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C13 compound treatment 213130.0 -78100.0 -0.53 292530.0 -1670.0 -0.01 -0.3815 -0.7231 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C14 compound treatment 284550.0 -6650.0 -0.04 307040.0 12800.0 0.09 0.034 0.3291 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C15 mock treatment 306880.0 15700.0 0.11 306520.0 12300.0 0.09 0.138 0.9963 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C16 mock treatment 280540.0 -10700.0 -0.07 390440.0 96200.0 0.7 0.4417 0.6307 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C17 compound treatment 247970.0 -43200.0 -0.29 250500.0 -43700.0 -0.32 -0.4302 -0.9992 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C18 compound treatment 334250.0 43100.0 0.29 262420.0 -31800.0 -0.23 0.043 0.116 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C19 compound treatment 254080.0 -37100.0 -0.25 189410.0 -105000.0 -0.76 -0.7137 -0.8933 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C20 compound treatment 202270.0 -88900.0 -0.6 210410.0 -83800.0 -0.61 -0.8538 -1.0 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C21 compound treatment 258100.0 -33100.0 -0.22 227900.0 -66300.0 -0.48 -0.4975 -0.9396 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C22 compound treatment 342080.0 50900.0 0.34 285920.0 -8280.0 -0.06 0.2007 0.5752 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C23 compound treatment 299540.0 8340.0 0.06 313230.0 19000.0 0.14 0.1373 0.9222 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 C24 compound treatment 356930.0 65700.0 0.44 297140.0 2940.0 0.02 0.3291 0.7402 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D01 compound treatment 271540.0 -19700.0 -0.13 204030.0 -90200.0 -0.65 -0.5555 -0.8339 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D02 compound treatment 290140.0 -1060.0 -0.01 378500.0 84300.0 0.61 0.4265 0.6988 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D03 compound treatment 362280.0 71100.0 0.48 289190.0 -5010.0 -0.04 0.314 0.6519 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D04 compound treatment 221850.0 -69300.0 -0.47 251760.0 -42400.0 -0.31 -0.5486 -0.979 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D05 compound treatment 256050.0 -35100.0 -0.24 369560.0 75400.0 0.55 0.2178 0.3661 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D06 compound treatment 253120.0 -38100.0 -0.26 313070.0 18900.0 0.14 -0.0853 -0.2929 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D07 compound treatment 202040.0 -89200.0 -0.6 379790.0 85600.0 0.62 0.0121 0.0141 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D08 compound treatment 270720.0 -20500.0 -0.14 379320.0 85100.0 0.62 0.3379 0.535 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D09 compound treatment 315280.0 24100.0 0.16 318580.0 24400.0 0.18 0.2399 0.9992 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D10 compound treatment 352680.0 61500.0 0.42 312810.0 18600.0 0.13 0.389 0.8908 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D11 mock treatment 291360.0 162.0 0.0 211250.0 -82900.0 -0.6 -0.4238 -0.7058 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D12 mock treatment 304490.0 13300.0 0.09 301130.0 6930.0 0.05 0.099 0.9622 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D13 compound treatment 217550.0 -73600.0 -0.5 262110.0 -32100.0 -0.23 -0.5161 -0.9398 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D14 compound treatment 278900.0 -12300.0 -0.08 337280.0 43100.0 0.31 0.1618 0.5012 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D15 mock treatment 295360.0 4160.0 0.03 280370.0 -13800.0 -0.1 -0.0509 -0.4895 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D16 mock treatment 238960.0 -52200.0 -0.35 281340.0 -12900.0 -0.09 -0.3154 -0.864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D17 compound treatment 309350.0 18200.0 0.12 355750.0 61600.0 0.45 0.4018 0.8694 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D18 compound treatment 357960.0 66800.0 0.45 443590.0 149000.0 1.08 1.0837 0.9248 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D19 compound treatment 287470.0 -3730.0 -0.03 244880.0 -49300.0 -0.36 -0.2703 -0.7551 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D20 compound treatment 301020.0 9820.0 0.07 313770.0 19600.0 0.14 0.1471 0.9403 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D21 compound treatment 279680.0 -11500.0 -0.08 347490.0 53300.0 0.39 0.2178 0.5533 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D22 compound treatment 384360.0 93200.0 0.63 284800.0 -9400.0 -0.07 0.397 0.627 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D23 compound treatment 304030.0 12800.0 0.09 321600.0 27400.0 0.2 0.2016 0.9311 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 D24 compound treatment 385820.0 94600.0 0.64 300720.0 6520.0 0.05 0.4855 0.7573 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E01 mock treatment 209960.0 -81200.0 -0.55 262630.0 -31600.0 -0.23 -0.5497 -0.9246 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E02 mock treatment 278160.0 -13000.0 -0.09 313300.0 19100.0 0.14 0.0355 0.2164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E03 compound treatment 273760.0 -17400.0 -0.12 384900.0 90700.0 0.66 0.381 0.5711 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E04 compound treatment 222880.0 -68300.0 -0.46 212110.0 -82100.0 -0.59 -0.7466 -0.9922 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E05 compound treatment 193310.0 -97900.0 -0.66 273220.0 -21000.0 -0.15 -0.5751 -0.8474 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E06 compound treatment 333440.0 42200.0 0.29 296250.0 2050.0 0.01 0.2123 0.7429 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E07 compound treatment 410520.0 119000.0 0.81 239550.0 -54600.0 -0.4 0.2904 0.3233 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E08 compound treatment 280070.0 -11100.0 -0.08 293760.0 -437.0 0.0 -0.0554 -0.7362 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E09 mock treatment 281810.0 -9390.0 -0.06 205600.0 -88600.0 -0.64 -0.4984 -0.7733 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E10 mock treatment 383000.0 91800.0 0.62 392290.0 98100.0 0.71 0.9407 0.9977 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E11 compound treatment 331840.0 40600.0 0.27 268390.0 -25800.0 -0.19 0.0621 0.1869 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E12 compound treatment 215700.0 -75500.0 -0.51 265670.0 -28500.0 -0.21 -0.5067 -0.9208 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E13 compound treatment 310040.0 18800.0 0.13 314360.0 20200.0 0.15 0.1932 0.9977 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E14 compound treatment 289850.0 -1350.0 -0.01 386520.0 92300.0 0.67 0.4661 0.6974 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E15 compound treatment 323220.0 32000.0 0.22 267520.0 -26700.0 -0.19 0.0164 0.0567 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E16 compound treatment 290690.0 -508.0 0.0 312000.0 17800.0 0.13 0.0887 0.688 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E17 mock treatment 324660.0 33500.0 0.23 284680.0 -9520.0 -0.07 0.1112 0.4703 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E18 mock treatment 333720.0 42500.0 0.29 230660.0 -63500.0 -0.46 -0.1221 -0.2251 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E19 compound treatment 284190.0 -7010.0 -0.05 310930.0 16700.0 0.12 0.0522 0.4011 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E20 compound treatment 329850.0 38700.0 0.26 296710.0 2510.0 0.02 0.1975 0.7545 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E21 compound treatment 302140.0 10900.0 0.07 329140.0 34900.0 0.25 0.2311 0.8771 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E22 compound treatment 340430.0 49200.0 0.33 237390.0 -56800.0 -0.41 -0.0556 -0.105 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E23 compound treatment 222170.0 -69000.0 -0.47 257480.0 -36700.0 -0.27 -0.5177 -0.9645 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 E24 compound treatment 294010.0 2810.0 0.02 373150.0 79000.0 0.57 0.4176 0.7302 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F01 mock treatment 194190.0 -97000.0 -0.66 260030.0 -34200.0 -0.25 -0.6384 -0.9112 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F02 mock treatment 297920.0 6720.0 0.05 363300.0 69100.0 0.5 0.3858 0.7682 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F03 compound treatment 231880.0 -59300.0 -0.4 391620.0 97400.0 0.71 0.2153 0.2654 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F04 compound treatment 231740.0 -59500.0 -0.4 378190.0 84000.0 0.61 0.1459 0.2001 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F05 compound treatment 142200.0 -149000.0 -1.01 138250.0 -156000.0 -1.13 -1.5101 -0.9984 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F06 compound treatment 344990.0 53800.0 0.36 155880.0 -138000.0 -1.0 -0.451 -0.4234 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F07 compound treatment 334760.0 43600.0 0.29 413650.0 119000.0 0.86 0.8196 0.8972 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F08 compound treatment 253400.0 -37800.0 -0.26 337120.0 42900.0 0.31 0.0391 0.0973 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F09 mock treatment 428500.0 137000.0 0.93 244440.0 -49800.0 -0.36 0.4013 0.4032 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F10 mock treatment 377460.0 86300.0 0.58 317760.0 23600.0 0.17 0.5328 0.8772 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F11 compound treatment 203160.0 -88000.0 -0.59 254820.0 -39400.0 -0.29 -0.6222 -0.9432 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F12 compound treatment 305560.0 14400.0 0.1 409870.0 116000.0 0.84 0.6607 0.7838 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F13 compound treatment 310040.0 18800.0 0.13 202430.0 -91800.0 -0.66 -0.3797 -0.5614 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F14 compound treatment 240990.0 -50200.0 -0.34 338050.0 43900.0 0.32 -0.0154 -0.0332 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F15 compound treatment 309440.0 18200.0 0.12 168050.0 -126000.0 -0.91 -0.5586 -0.6062 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F16 compound treatment 406660.0 115000.0 0.78 237320.0 -56900.0 -0.41 0.2605 0.2953 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F17 mock treatment 381440.0 90200.0 0.61 278850.0 -15300.0 -0.11 0.3526 0.5689 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F18 mock treatment 297710.0 6510.0 0.04 373350.0 79200.0 0.57 0.4363 0.7592 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F19 compound treatment 247880.0 -43300.0 -0.29 340890.0 46700.0 0.34 0.032 0.0717 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F20 compound treatment 279280.0 -11900.0 -0.08 373550.0 79400.0 0.57 0.3492 0.6021 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F21 compound treatment 237830.0 -53400.0 -0.36 296480.0 2280.0 0.02 -0.2433 -0.674 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F22 compound treatment 440390.0 149000.0 1.01 317330.0 23100.0 0.17 0.8312 0.8134 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F23 compound treatment 321970.0 30800.0 0.21 348480.0 54300.0 0.39 0.4249 0.9557 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 F24 compound treatment 301470.0 10300.0 0.07 283760.0 -10400.0 -0.08 -0.0043 -0.0424 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G01 compound treatment 342660.0 51500.0 0.35 374660.0 80500.0 0.58 0.6577 0.9696 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G02 compound treatment 328230.0 37000.0 0.25 337540.0 43300.0 0.31 0.3988 0.9937 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G03 mock treatment 310310.0 19100.0 0.13 363560.0 69400.0 0.5 0.4464 0.8609 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G04 mock treatment 299550.0 8350.0 0.06 413530.0 119000.0 0.86 0.6507 0.7517 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G05 compound treatment 306600.0 15400.0 0.1 336050.0 41900.0 0.3 0.2878 0.8985 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G06 compound treatment 208660.0 -82500.0 -0.56 267230.0 -27000.0 -0.2 -0.5324 -0.901 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G07 compound treatment 385220.0 94000.0 0.64 380320.0 86100.0 0.62 0.8901 1.0 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G08 compound treatment 492060.0 201000.0 1.36 356280.0 62100.0 0.45 1.2775 0.8935 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G09 compound treatment 272000.0 -19200.0 -0.13 421660.0 127000.0 0.92 0.5607 0.6018 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G10 compound treatment 430850.0 140000.0 0.94 285830.0 -8370.0 -0.06 0.6244 0.6604 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G11 compound treatment 360900.0 69700.0 0.47 211590.0 -82600.0 -0.6 -0.0898 -0.118 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G12 compound treatment 357140.0 65900.0 0.45 254560.0 -39600.0 -0.29 0.1122 0.2117 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G13 compound treatment 399250.0 108000.0 0.73 191780.0 -102000.0 -0.74 -0.008 -0.0077 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G14 compound treatment 298440.0 7240.0 0.05 317380.0 23200.0 0.17 0.1533 0.8768 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G15 compound treatment 337710.0 46500.0 0.31 233310.0 -60900.0 -0.44 -0.0894 -0.1652 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G16 compound treatment 247520.0 -43700.0 -0.3 278980.0 -15200.0 -0.11 -0.2866 -0.9097 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G17 compound treatment 317530.0 26300.0 0.18 312260.0 18100.0 0.13 0.2183 0.9885 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G18 compound treatment 339480.0 48300.0 0.33 297470.0 3270.0 0.02 0.2474 0.7565 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G19 mock treatment 280910.0 -10300.0 -0.07 330920.0 36700.0 0.27 0.1388 0.5052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G20 mock treatment 371940.0 80700.0 0.55 256190.0 -38000.0 -0.28 0.1912 0.313 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G21 compound treatment 290240.0 -958.0 -0.01 298940.0 4740.0 0.03 0.0197 0.5639 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G22 compound treatment 251200.0 -40000.0 -0.27 327890.0 33700.0 0.24 -0.0186 -0.0512 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G23 compound treatment 277880.0 -13300.0 -0.09 334350.0 40200.0 0.29 0.1419 0.4664 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 G24 compound treatment 285620.0 -5580.0 -0.04 302040.0 7840.0 0.06 0.0135 0.198 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H01 compound treatment 283040.0 -8160.0 -0.06 225660.0 -68500.0 -0.5 -0.3898 -0.7809 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H02 compound treatment 242880.0 -48300.0 -0.33 432000.0 138000.0 1.0 0.4745 0.4521 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H03 mock treatment 262770.0 -28400.0 -0.19 222200.0 -72000.0 -0.52 -0.5044 -0.908 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H04 mock treatment 226040.0 -65200.0 -0.44 236960.0 -57200.0 -0.41 -0.6043 -0.9995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H05 compound treatment 262830.0 -28400.0 -0.19 242730.0 -51500.0 -0.37 -0.399 -0.9523 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H06 compound treatment 274530.0 -16700.0 -0.11 288320.0 -5880.0 -0.04 -0.1097 -0.9114 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H07 compound treatment 269220.0 -22000.0 -0.15 230900.0 -63300.0 -0.46 -0.429 -0.8907 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H08 compound treatment 307300.0 16100.0 0.11 268390.0 -25800.0 -0.19 -0.0552 -0.2552 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H09 compound treatment 192840.0 -98400.0 -0.66 218620.0 -75600.0 -0.55 -0.8568 -0.9953 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H10 compound treatment 286050.0 -5150.0 -0.03 305600.0 11400.0 0.08 0.0338 0.377 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H11 compound treatment 519710.0 229000.0 1.54 240040.0 -54200.0 -0.39 0.8146 0.5113 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H12 compound treatment 240120.0 -51100.0 -0.35 199250.0 -94900.0 -0.69 -0.73 -0.9492 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H13 compound treatment 313000.0 21800.0 0.15 222460.0 -71700.0 -0.52 -0.263 -0.4873 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H14 compound treatment 310240.0 19000.0 0.13 272710.0 -21500.0 -0.16 -0.019 -0.0942 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H15 compound treatment 281440.0 -9760.0 -0.07 354210.0 60000.0 0.43 0.2606 0.593 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H16 compound treatment 223540.0 -67700.0 -0.46 244810.0 -49400.0 -0.36 -0.5761 -0.9926 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H17 compound treatment 314890.0 23700.0 0.16 280680.0 -13500.0 -0.1 0.044 0.2345 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H18 compound treatment 311850.0 20700.0 0.14 397220.0 103000.0 0.75 0.626 0.8251 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H19 mock treatment 260070.0 -31100.0 -0.21 392200.0 98000.0 0.71 0.3529 0.477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H20 mock treatment 238570.0 -52600.0 -0.36 327000.0 32800.0 0.24 -0.0835 -0.1954 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H21 compound treatment 301160.0 9960.0 0.07 261680.0 -32500.0 -0.24 -0.1188 -0.4854 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H22 compound treatment 445680.0 154000.0 1.04 245460.0 -48700.0 -0.35 0.4886 0.4435 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H23 compound treatment 315200.0 24000.0 0.16 296590.0 2390.0 0.02 0.1269 0.7782 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 H24 compound treatment 325460.0 34300.0 0.23 251300.0 -42900.0 -0.31 -0.0559 -0.1443 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I01 compound treatment 325610.0 34400.0 0.23 203170.0 -91000.0 -0.66 -0.3015 -0.4315 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I02 compound treatment 272640.0 -18600.0 -0.13 227960.0 -66200.0 -0.48 -0.4277 -0.863 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I03 compound treatment 376720.0 85500.0 0.58 280710.0 -13500.0 -0.1 0.3396 0.5794 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I04 compound treatment 314520.0 23300.0 0.16 258770.0 -35400.0 -0.26 -0.0699 -0.2323 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I05 mock treatment 288110.0 -3090.0 -0.02 222180.0 -72000.0 -0.52 -0.3834 -0.7348 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I06 mock treatment 436760.0 146000.0 0.98 216520.0 -77700.0 -0.56 0.2979 0.2629 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I07 compound treatment 206030.0 -85200.0 -0.58 271750.0 -22400.0 -0.16 -0.5218 -0.8726 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I08 compound treatment 320710.0 29500.0 0.2 348760.0 54600.0 0.39 0.4203 0.9499 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I09 compound treatment 251550.0 -39600.0 -0.27 371760.0 77600.0 0.56 0.2076 0.3337 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I10 compound treatment 301510.0 10300.0 0.07 186600.0 -108000.0 -0.78 -0.5015 -0.6413 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I11 compound treatment 435880.0 145000.0 0.98 346810.0 52600.0 0.38 0.9606 0.9156 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I12 compound treatment 147040.0 -144000.0 -0.97 295840.0 1640.0 0.01 -0.6803 -0.6984 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I13 compound treatment 317280.0 26100.0 0.18 204670.0 -89500.0 -0.65 -0.3336 -0.4968 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I14 compound treatment 230100.0 -61100.0 -0.41 419760.0 126000.0 0.91 0.3508 0.3514 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I15 compound treatment 446420.0 155000.0 1.05 347250.0 53100.0 0.38 1.0132 0.9071 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I16 compound treatment 330470.0 39300.0 0.27 250810.0 -43400.0 -0.31 -0.0345 -0.0838 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I17 compound treatment 244240.0 -47000.0 -0.32 380930.0 86700.0 0.63 0.2196 0.3122 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I18 compound treatment 308080.0 16900.0 0.11 358690.0 64500.0 0.47 0.4108 0.8547 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I19 compound treatment 307470.0 16300.0 0.11 242730.0 -51500.0 -0.37 -0.1857 -0.4781 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I20 compound treatment 337940.0 46700.0 0.32 235700.0 -58500.0 -0.42 -0.0761 -0.1441 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I21 mock treatment 331560.0 40400.0 0.27 305120.0 10900.0 0.08 0.2488 0.876 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I22 mock treatment 327890.0 36700.0 0.25 337440.0 43200.0 0.31 0.3967 0.9933 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I23 compound treatment 317390.0 26200.0 0.18 353050.0 58900.0 0.43 0.4264 0.9243 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 I24 compound treatment 256870.0 -34300.0 -0.23 236860.0 -57300.0 -0.42 -0.4575 -0.9622 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J01 compound treatment 210600.0 -80600.0 -0.54 364640.0 70400.0 0.51 -0.0245 -0.0328 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J02 compound treatment 251360.0 -39800.0 -0.27 298290.0 4090.0 0.03 -0.1694 -0.6255 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J03 compound treatment 234660.0 -56500.0 -0.38 138800.0 -155000.0 -1.12 -1.0656 -0.8969 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J04 compound treatment 353730.0 62500.0 0.42 240750.0 -53400.0 -0.39 0.0252 0.044 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J05 mock treatment 195430.0 -95800.0 -0.65 194290.0 -99900.0 -0.72 -0.969 -0.9985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J06 mock treatment 227290.0 -63900.0 -0.43 169600.0 -125000.0 -0.9 -0.9431 -0.9431 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J07 compound treatment 182080.0 -109000.0 -0.74 206210.0 -88000.0 -0.64 -0.9717 -0.9973 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J08 compound treatment 251040.0 -40200.0 -0.27 185880.0 -108000.0 -0.78 -0.7463 -0.8995 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J09 compound treatment 365290.0 74100.0 0.5 199460.0 -94700.0 -0.69 -0.1309 -0.1542 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J10 compound treatment 216490.0 -74700.0 -0.5 178280.0 -116000.0 -0.84 -0.9503 -0.9704 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J11 compound treatment 303040.0 11800.0 0.08 150470.0 -144000.0 -1.04 -0.6791 -0.6508 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J12 compound treatment 257390.0 -33800.0 -0.23 264670.0 -29500.0 -0.21 -0.3127 -0.9994 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J13 compound treatment 300840.0 9640.0 0.07 176640.0 -118000.0 -0.85 -0.5557 -0.6511 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J14 compound treatment 252210.0 -39000.0 -0.26 261920.0 -32300.0 -0.23 -0.3515 -0.9982 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J15 compound treatment 288480.0 -2720.0 -0.02 226000.0 -68200.0 -0.49 -0.3621 -0.7329 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J16 compound treatment 177870.0 -113000.0 -0.77 192750.0 -101000.0 -0.73 -1.0607 -0.9998 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J17 compound treatment 322400.0 31200.0 0.21 200160.0 -94000.0 -0.68 -0.3323 -0.4663 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J18 compound treatment 304730.0 13500.0 0.09 231770.0 -62400.0 -0.45 -0.2549 -0.5528 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J19 compound treatment 283150.0 -8050.0 -0.05 259850.0 -34300.0 -0.25 -0.2143 -0.8419 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J20 compound treatment 289120.0 -2080.0 -0.01 202170.0 -92000.0 -0.67 -0.481 -0.7218 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J21 mock treatment 244420.0 -46800.0 -0.32 283000.0 -11200.0 -0.08 -0.2808 -0.8606 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J22 mock treatment 294080.0 2880.0 0.02 265950.0 -28200.0 -0.2 -0.1308 -0.6369 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J23 compound treatment 312910.0 21700.0 0.15 278280.0 -15900.0 -0.12 0.0223 0.1193 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 J24 compound treatment 260760.0 -30400.0 -0.21 236480.0 -57700.0 -0.42 -0.4409 -0.9467 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K01 compound treatment 326270.0 35100.0 0.24 341990.0 47800.0 0.35 0.4122 0.983 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K02 compound treatment 182900.0 -108000.0 -0.73 384160.0 90000.0 0.65 -0.0569 -0.0581 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K03 compound treatment 449620.0 158000.0 1.07 189030.0 -105000.0 -0.76 0.2186 0.1664 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K04 compound treatment 209930.0 -81300.0 -0.55 335620.0 41400.0 0.3 -0.1763 -0.2817 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K05 compound treatment 249560.0 -41600.0 -0.28 388480.0 94300.0 0.68 0.2837 0.3843 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K06 compound treatment 225690.0 -65500.0 -0.44 163590.0 -131000.0 -0.95 -0.9815 -0.9402 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K07 mock treatment 281700.0 -9500.0 -0.06 322720.0 28500.0 0.21 0.1006 0.4654 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K08 mock treatment 182900.0 -108000.0 -0.73 205640.0 -88600.0 -0.64 -0.9707 -0.9978 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K09 compound treatment 408240.0 117000.0 0.79 431260.0 137000.0 0.99 1.2608 0.9937 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K10 compound treatment 343040.0 51800.0 0.35 310210.0 16000.0 0.12 0.3297 0.8935 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K11 compound treatment 227320.0 -63900.0 -0.43 192980.0 -101000.0 -0.73 -0.8233 -0.9682 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K12 compound treatment 298450.0 7250.0 0.05 403050.0 109000.0 0.79 0.5918 0.7496 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K13 compound treatment 302880.0 11700.0 0.08 269920.0 -24300.0 -0.18 -0.0685 -0.3553 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K14 compound treatment 279920.0 -11300.0 -0.08 264030.0 -30200.0 -0.22 -0.2083 -0.9006 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K15 mock treatment 372280.0 81100.0 0.55 380860.0 86700.0 0.63 0.831 0.9977 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K16 mock treatment 294000.0 2800.0 0.02 265020.0 -29200.0 -0.21 -0.136 -0.6412 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K17 compound treatment 352030.0 60800.0 0.41 380740.0 86500.0 0.63 0.7336 0.9791 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K18 compound treatment 288160.0 -3040.0 -0.02 357380.0 63200.0 0.46 0.3089 0.6747 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K19 compound treatment 214330.0 -76900.0 -0.52 278720.0 -15500.0 -0.11 -0.4465 -0.8403 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K20 compound treatment 284480.0 -6720.0 -0.05 454770.0 161000.0 1.16 0.7898 0.679 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K21 compound treatment 282660.0 -8540.0 -0.06 323840.0 29600.0 0.21 0.1109 0.4993 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K22 compound treatment 277350.0 -13800.0 -0.09 292670.0 -1530.0 -0.01 -0.074 -0.7852 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K23 mock treatment 455520.0 164000.0 1.11 309600.0 15400.0 0.11 0.8639 0.7742 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 K24 mock treatment 270760.0 -20400.0 -0.14 348580.0 54400.0 0.39 0.1807 0.4332 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L01 compound treatment 215590.0 -75600.0 -0.51 235810.0 -58400.0 -0.42 -0.6601 -0.9956 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L02 compound treatment 343240.0 52000.0 0.35 271930.0 -22300.0 -0.16 0.1347 0.3481 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L03 compound treatment 209500.0 -81700.0 -0.55 227310.0 -66900.0 -0.48 -0.7327 -0.9979 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L04 compound treatment 242240.0 -49000.0 -0.33 283810.0 -10400.0 -0.08 -0.2871 -0.8462 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L05 compound treatment 187960.0 -103000.0 -0.7 203280.0 -90900.0 -0.66 -0.9586 -0.9996 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L06 compound treatment 343710.0 52500.0 0.35 246400.0 -47800.0 -0.35 0.0062 0.0126 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L07 mock treatment 258300.0 -32900.0 -0.22 422010.0 128000.0 0.93 0.4971 0.5224 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L08 mock treatment 499970.0 209000.0 1.41 361850.0 67700.0 0.49 1.3438 0.8999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L09 compound treatment 226180.0 -65000.0 -0.44 219910.0 -74300.0 -0.54 -0.6909 -0.995 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L10 compound treatment 388580.0 97400.0 0.66 190670.0 -104000.0 -0.75 -0.0647 -0.0648 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L11 compound treatment 281140.0 -10100.0 -0.07 190620.0 -104000.0 -0.75 -0.5782 -0.768 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L12 compound treatment 486250.0 195000.0 1.32 369920.0 75700.0 0.55 1.3195 0.9244 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L13 compound treatment 243840.0 -47400.0 -0.32 210900.0 -83300.0 -0.6 -0.6526 -0.9561 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L14 compound treatment 286930.0 -4270.0 -0.03 283520.0 -10700.0 -0.08 -0.075 -0.9097 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L15 mock treatment 218370.0 -72800.0 -0.49 433530.0 139000.0 1.01 0.3652 0.3255 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L16 mock treatment 266210.0 -25000.0 -0.17 259880.0 -34300.0 -0.25 -0.295 -0.9823 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L17 compound treatment 385000.0 93800.0 0.63 365600.0 71400.0 0.52 0.8137 0.9949 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L18 compound treatment 247050.0 -44100.0 -0.3 302530.0 8330.0 0.06 -0.1683 -0.5529 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L19 compound treatment 203940.0 -87300.0 -0.59 258160.0 -36000.0 -0.26 -0.6014 -0.9328 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L20 compound treatment 223910.0 -67300.0 -0.45 319570.0 25400.0 0.18 -0.1916 -0.3908 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L21 compound treatment 241940.0 -49300.0 -0.33 252320.0 -41900.0 -0.3 -0.4497 -0.9989 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L22 compound treatment 268380.0 -22800.0 -0.15 385130.0 90900.0 0.66 0.3564 0.5272 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L23 mock treatment 267840.0 -23400.0 -0.16 462810.0 169000.0 1.22 0.7515 0.6106 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 L24 mock treatment 273120.0 -18100.0 -0.12 313060.0 18900.0 0.14 0.0102 0.0556 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M01 compound treatment 424330.0 133000.0 0.9 320020.0 25800.0 0.19 0.7683 0.8362 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M02 compound treatment 208860.0 -82300.0 -0.56 237250.0 -56900.0 -0.41 -0.6849 -0.9891 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M03 compound treatment 326720.0 35500.0 0.24 368650.0 74500.0 0.54 0.5508 0.9336 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M04 compound treatment 174420.0 -117000.0 -0.79 201070.0 -93100.0 -0.67 -1.0346 -0.9969 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M05 compound treatment 224400.0 -66800.0 -0.45 183310.0 -111000.0 -0.8 -0.8867 -0.9629 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M06 compound treatment 324960.0 33800.0 0.23 239470.0 -54700.0 -0.4 -0.1188 -0.2599 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M07 compound treatment 383640.0 92400.0 0.62 337920.0 43700.0 0.32 0.6655 0.9504 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M08 compound treatment 369880.0 78700.0 0.53 121720.0 -172000.0 -1.25 -0.5069 -0.3736 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M09 mock treatment 226280.0 -64900.0 -0.44 314750.0 20600.0 0.15 -0.205 -0.4425 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M10 mock treatment 315860.0 24700.0 0.17 468640.0 174000.0 1.26 1.0108 0.7935 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M11 compound treatment 331540.0 40300.0 0.27 221660.0 -72500.0 -0.53 -0.1785 -0.3018 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M12 compound treatment 373440.0 82200.0 0.56 338400.0 44200.0 0.32 0.6192 0.9656 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M13 mock treatment 436750.0 146000.0 0.98 257310.0 -36900.0 -0.27 0.5066 0.4971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M14 mock treatment 331040.0 39800.0 0.27 358770.0 64600.0 0.47 0.5209 0.9656 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M15 compound treatment 457120.0 166000.0 1.12 409340.0 115000.0 0.83 1.3821 0.9893 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M16 compound treatment 351900.0 60700.0 0.41 397920.0 104000.0 0.75 0.8209 0.9595 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M17 compound treatment 307480.0 16300.0 0.11 290370.0 -3830.0 -0.03 0.0582 0.513 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M18 compound treatment 317370.0 26200.0 0.18 290400.0 -3800.0 -0.03 0.1056 0.5901 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M19 compound treatment 239170.0 -52000.0 -0.35 396570.0 102000.0 0.74 0.2754 0.3358 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M20 compound treatment 383100.0 91900.0 0.62 299270.0 5070.0 0.04 0.4651 0.7476 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M21 compound treatment 303530.0 12300.0 0.08 285960.0 -8240.0 -0.06 0.0168 0.1635 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M22 compound treatment 308200.0 17000.0 0.11 340320.0 46100.0 0.33 0.3173 0.8987 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M23 compound treatment 320030.0 28800.0 0.19 321030.0 26800.0 0.19 0.2751 1.0 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 M24 compound treatment 277460.0 -13700.0 -0.09 307300.0 13100.0 0.09 0.0014 0.0108 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N01 compound treatment 268350.0 -22800.0 -0.15 189470.0 -105000.0 -0.76 -0.6452 -0.834 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N02 compound treatment 193450.0 -97700.0 -0.66 216160.0 -78000.0 -0.56 -0.8665 -0.997 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N03 compound treatment 191140.0 -100000.0 -0.68 365730.0 71500.0 0.52 -0.1119 -0.1314 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N04 compound treatment 189840.0 -101000.0 -0.68 217090.0 -77100.0 -0.56 -0.879 -0.9948 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N05 compound treatment 170290.0 -121000.0 -0.82 235560.0 -58600.0 -0.42 -0.8778 -0.9535 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N06 compound treatment 185390.0 -106000.0 -0.71 425850.0 132000.0 0.95 0.1684 0.1413 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N07 compound treatment 258020.0 -33200.0 -0.22 376670.0 82500.0 0.6 0.2636 0.4134 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N08 compound treatment 226530.0 -64700.0 -0.44 295900.0 1700.0 0.01 -0.3003 -0.6869 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N09 mock treatment 300480.0 9280.0 0.06 179730.0 -114000.0 -0.83 -0.5416 -0.6517 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N10 mock treatment 320280.0 29100.0 0.2 257820.0 -36400.0 -0.26 -0.0473 -0.1438 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N11 compound treatment 313980.0 22800.0 0.15 322720.0 28500.0 0.21 0.2548 0.9895 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N12 compound treatment 353540.0 62300.0 0.42 176590.0 -118000.0 -0.85 -0.3041 -0.3202 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N13 mock treatment 332750.0 41600.0 0.28 165800.0 -128000.0 -0.93 -0.4587 -0.4724 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N14 mock treatment 247100.0 -44100.0 -0.3 368640.0 74400.0 0.54 0.1704 0.2767 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N15 compound treatment 328340.0 37100.0 0.25 397180.0 103000.0 0.75 0.7046 0.8958 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N16 compound treatment 266460.0 -24700.0 -0.17 189780.0 -104000.0 -0.76 -0.6527 -0.8431 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N17 compound treatment 335360.0 44200.0 0.3 222080.0 -72100.0 -0.52 -0.1581 -0.263 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N18 compound treatment 299490.0 8290.0 0.06 232030.0 -62200.0 -0.45 -0.2786 -0.6143 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N19 compound treatment 335120.0 43900.0 0.3 239910.0 -54300.0 -0.39 -0.068 -0.1381 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N20 compound treatment 191900.0 -99300.0 -0.67 249700.0 -44500.0 -0.32 -0.7022 -0.9435 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N21 compound treatment 356050.0 64900.0 0.44 275200.0 -19000.0 -0.14 0.2126 0.4629 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N22 compound treatment 384720.0 93500.0 0.63 385180.0 91000.0 0.66 0.9125 0.9998 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N23 compound treatment 266850.0 -24300.0 -0.16 333060.0 38900.0 0.28 0.0826 0.2534 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 N24 compound treatment 256450.0 -34700.0 -0.23 405250.0 111000.0 0.8 0.4024 0.4805 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O01 compound treatment 256160.0 -35000.0 -0.24 255970.0 -38200.0 -0.28 -0.3631 -0.997 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O02 compound treatment 262770.0 -28400.0 -0.19 229120.0 -65100.0 -0.47 -0.4689 -0.9217 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O03 compound treatment 257280.0 -33900.0 -0.23 325030.0 30800.0 0.22 -0.0042 -0.0132 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O04 compound treatment 244230.0 -47000.0 -0.32 259950.0 -34200.0 -0.25 -0.3997 -0.9925 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O05 compound treatment 255720.0 -35500.0 -0.24 185280.0 -109000.0 -0.79 -0.727 -0.8822 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O06 compound treatment 257280.0 -33900.0 -0.23 346730.0 52500.0 0.38 0.1068 0.2406 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O07 compound treatment 174270.0 -117000.0 -0.79 204480.0 -89700.0 -0.65 -1.0179 -0.9953 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O08 compound treatment 263000.0 -28200.0 -0.19 240810.0 -53400.0 -0.39 -0.408 -0.9469 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O09 compound treatment 195420.0 -95800.0 -0.65 327050.0 32900.0 0.24 -0.2894 -0.4198 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O10 compound treatment 263840.0 -27400.0 -0.18 190520.0 -104000.0 -0.75 -0.6614 -0.8557 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O11 mock treatment 260450.0 -30700.0 -0.21 186130.0 -108000.0 -0.78 -0.7001 -0.8649 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O12 mock treatment 213070.0 -78100.0 -0.53 224720.0 -69500.0 -0.5 -0.7289 -0.9997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O13 compound treatment 227170.0 -64000.0 -0.43 199260.0 -94900.0 -0.69 -0.7919 -0.9751 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O14 compound treatment 213530.0 -77700.0 -0.52 253480.0 -40700.0 -0.29 -0.5795 -0.9628 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O15 compound treatment 237920.0 -53300.0 -0.36 248160.0 -46000.0 -0.33 -0.4902 -0.9993 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O16 compound treatment 285510.0 -5690.0 -0.04 360500.0 66300.0 0.48 0.3122 0.6484 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O17 compound treatment 201060.0 -90100.0 -0.61 271520.0 -22700.0 -0.16 -0.5467 -0.8668 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O18 compound treatment 339080.0 47900.0 0.32 399860.0 106000.0 0.76 0.7696 0.9267 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O19 compound treatment 237410.0 -53800.0 -0.36 281120.0 -13100.0 -0.09 -0.3239 -0.8625 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O20 compound treatment 239520.0 -51700.0 -0.35 194420.0 -99800.0 -0.72 -0.7576 -0.9444 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O21 compound treatment 314530.0 23300.0 0.16 307370.0 13200.0 0.1 0.1789 0.971 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O22 compound treatment 279580.0 -11600.0 -0.08 282080.0 -12100.0 -0.09 -0.1175 -0.9985 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O23 compound treatment 243170.0 -48000.0 -0.32 357130.0 62900.0 0.46 0.0927 0.1657 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 O24 compound treatment 258260.0 -32900.0 -0.22 291840.0 -2360.0 -0.02 -0.1694 -0.7591 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P01 compound treatment 233530.0 -57700.0 -0.39 212280.0 -81900.0 -0.59 -0.6948 -0.9793 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P02 compound treatment 233160.0 -58000.0 -0.39 293950.0 -247.0 0.0 -0.2786 -0.7103 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P03 compound treatment 172720.0 -118000.0 -0.8 177490.0 -117000.0 -0.84 -1.1635 -0.9996 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P04 compound treatment 151240.0 -140000.0 -0.95 197300.0 -96900.0 -0.7 -1.1647 -0.9892 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P05 compound treatment 158620.0 -133000.0 -0.9 173000.0 -121000.0 -0.88 -1.2538 -0.9999 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P06 compound treatment 148320.0 -143000.0 -0.97 155680.0 -139000.0 -1.0 -1.3917 -0.9998 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P07 compound treatment 182740.0 -108000.0 -0.73 186050.0 -108000.0 -0.78 -1.0718 -0.9995 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P08 compound treatment 167220.0 -124000.0 -0.84 188850.0 -105000.0 -0.76 -1.1316 -0.9989 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P09 compound treatment 181280.0 -110000.0 -0.74 217370.0 -76800.0 -0.56 -0.9184 -0.9898 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P10 compound treatment 168570.0 -123000.0 -0.83 174720.0 -119000.0 -0.86 -1.1975 -0.9998 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P11 mock treatment 206920.0 -84300.0 -0.57 231400.0 -62800.0 -0.45 -0.7241 -0.9938 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P12 mock treatment 214970.0 -76200.0 -0.52 132100.0 -162000.0 -1.17 -1.1939 -0.9317 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P13 compound treatment 117960.0 -173000.0 -1.17 123610.0 -171000.0 -1.23 -1.7009 -0.9996 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P14 compound treatment 168270.0 -123000.0 -0.83 218970.0 -75200.0 -0.54 -0.9724 -0.979 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P15 compound treatment 253680.0 -37500.0 -0.25 204860.0 -89300.0 -0.65 -0.6365 -0.9164 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P16 compound treatment 212370.0 -78800.0 -0.53 153160.0 -141000.0 -1.02 -1.0986 -0.954 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P17 compound treatment 200880.0 -90300.0 -0.61 187780.0 -106000.0 -0.77 -0.9762 -0.9933 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P18 compound treatment 143390.0 -148000.0 -1.0 159970.0 -134000.0 -0.97 -1.3933 -0.9999 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P19 compound treatment 203680.0 -87500.0 -0.59 181600.0 -113000.0 -0.82 -0.9945 -0.9876 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P20 compound treatment 194940.0 -96300.0 -0.65 187280.0 -107000.0 -0.77 -1.0072 -0.9963 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P21 compound treatment 314270.0 23100.0 0.16 189920.0 -104000.0 -0.75 -0.4235 -0.5495 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P22 compound treatment 223200.0 -68000.0 -0.46 161860.0 -132000.0 -0.96 -1.0023 -0.9434 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P23 compound treatment 190720.0 -100000.0 -0.68 162670.0 -132000.0 -0.95 -1.1533 -0.9863 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2101 P24 compound treatment 212990.0 -78200.0 -0.53 252680.0 -41500.0 -0.3 -0.5862 -0.9642 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A01 compound treatment 227470.0 -126000.0 -0.85 286850.0 -98100.0 -0.71 -1.1044 -0.9959 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A02 compound treatment 73440.0 -280000.0 -1.89 81060.0 -304000.0 -2.2 -2.8937 -0.9972 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A03 compound treatment 162760.0 -191000.0 -1.29 174920.0 -210000.0 -1.52 -1.9865 -0.9966 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A04 compound treatment 251040.0 -102000.0 -0.69 160060.0 -225000.0 -1.63 -1.6408 -0.9275 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A05 compound treatment 303700.0 -49800.0 -0.34 422310.0 37400.0 0.27 -0.0468 -0.1084 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A06 compound treatment 227480.0 -126000.0 -0.85 297280.0 -87700.0 -0.63 -1.051 -0.9895 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A07 compound treatment 209480.0 -144000.0 -0.97 242090.0 -143000.0 -1.03 -1.4195 -0.9995 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A08 compound treatment 90240.0 -263000.0 -1.78 100500.0 -284000.0 -2.06 -2.7139 -0.9973 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A09 compound treatment 259590.0 -93900.0 -0.63 300320.0 -84600.0 -0.61 -0.882 -0.9998 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A10 compound treatment 162680.0 -191000.0 -1.29 174410.0 -211000.0 -1.52 -1.9895 -0.9965 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A11 compound treatment 303250.0 -50300.0 -0.34 318760.0 -66200.0 -0.48 -0.579 -0.9858 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A12 compound treatment 160660.0 -193000.0 -1.3 151360.0 -234000.0 -1.69 -2.1171 -0.9917 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A13 mock treatment 312330.0 -41200.0 -0.28 389790.0 4840.0 0.04 -0.172 -0.6132 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A14 mock treatment 352260.0 -1270.0 -0.01 364200.0 -20700.0 -0.15 -0.1122 -0.7462 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A15 compound treatment 263840.0 -89700.0 -0.61 232550.0 -152000.0 -1.1 -1.2086 -0.9602 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A16 compound treatment 220320.0 -133000.0 -0.9 190080.0 -195000.0 -1.41 -1.6339 -0.9764 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A17 compound treatment 198110.0 -155000.0 -1.05 205820.0 -179000.0 -1.3 -1.6594 -0.9945 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A18 compound treatment 156360.0 -197000.0 -1.33 120690.0 -264000.0 -1.91 -2.2947 -0.9844 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A19 compound treatment 110910.0 -243000.0 -1.64 85980.0 -299000.0 -2.16 -2.6895 -0.9906 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A20 compound treatment 213120.0 -140000.0 -0.95 227630.0 -157000.0 -1.14 -1.4761 -0.9959 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A21 compound treatment 308160.0 -45400.0 -0.31 306650.0 -78300.0 -0.57 -0.6175 -0.9584 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A22 compound treatment 124320.0 -229000.0 -1.55 117880.0 -267000.0 -1.93 -2.4621 -0.994 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A23 compound treatment 239260.0 -114000.0 -0.77 216970.0 -168000.0 -1.22 -1.4058 -0.976 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 A24 compound treatment 220130.0 -133000.0 -0.9 296810.0 -88100.0 -0.64 -1.0885 -0.9857 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B01 compound treatment 365280.0 11800.0 0.08 399680.0 14700.0 0.11 0.1316 0.9895 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B02 compound treatment 159520.0 -194000.0 -1.31 213240.0 -172000.0 -1.24 -1.8058 -0.9996 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B03 compound treatment 256240.0 -97300.0 -0.66 274090.0 -111000.0 -0.8 -1.0323 -0.9951 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B04 compound treatment 318530.0 -35000.0 -0.24 282720.0 -102000.0 -0.74 -0.6905 -0.8888 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B05 compound treatment 358720.0 5190.0 0.04 210240.0 -175000.0 -1.26 -0.8695 -0.6872 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B06 compound treatment 331200.0 -22300.0 -0.15 311870.0 -73100.0 -0.53 -0.4807 -0.8739 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B07 compound treatment 295170.0 -58400.0 -0.39 354130.0 -30800.0 -0.22 -0.4366 -0.9636 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B08 compound treatment 306490.0 -47000.0 -0.32 367440.0 -17500.0 -0.13 -0.3143 -0.9187 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B09 compound treatment 372860.0 19300.0 0.13 303080.0 -81900.0 -0.59 -0.3267 -0.5383 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B10 compound treatment 349880.0 -3650.0 -0.02 324590.0 -60400.0 -0.44 -0.3264 -0.7458 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B11 compound treatment 353730.0 204.0 0.0 353120.0 -31800.0 -0.23 -0.1619 -0.7029 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B12 compound treatment 261220.0 -92300.0 -0.62 298350.0 -86600.0 -0.63 -0.8843 -1.0 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B13 mock treatment 408050.0 54500.0 0.37 426570.0 41600.0 0.3 0.4736 0.995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B14 mock treatment 401340.0 47800.0 0.32 405560.0 20600.0 0.15 0.334 0.9384 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B15 compound treatment 307520.0 -46000.0 -0.31 335570.0 -49400.0 -0.36 -0.4726 -0.9976 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B16 compound treatment 308230.0 -45300.0 -0.31 416920.0 32000.0 0.23 -0.0528 -0.1375 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B17 compound treatment 324280.0 -29200.0 -0.2 278960.0 -106000.0 -0.77 -0.6822 -0.8611 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B18 compound treatment 323000.0 -30500.0 -0.21 265650.0 -119000.0 -0.86 -0.7565 -0.852 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B19 compound treatment 319470.0 -34100.0 -0.23 342040.0 -42900.0 -0.31 -0.3823 -0.9891 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B20 compound treatment 244050.0 -109000.0 -0.74 278560.0 -106000.0 -0.77 -1.0676 -0.9998 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B21 compound treatment 359450.0 5920.0 0.04 258140.0 -127000.0 -0.92 -0.6208 -0.6756 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B22 compound treatment 213440.0 -140000.0 -0.95 316080.0 -68900.0 -0.5 -1.0218 -0.9551 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B23 compound treatment 316550.0 -37000.0 -0.25 225280.0 -160000.0 -1.16 -0.9939 -0.8405 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 B24 compound treatment 241320.0 -112000.0 -0.76 250800.0 -134000.0 -0.97 -1.2228 -0.9925 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C01 compound treatment 331120.0 -22400.0 -0.15 343840.0 -41100.0 -0.3 -0.3175 -0.9509 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C02 compound treatment 148210.0 -205000.0 -1.39 148170.0 -237000.0 -1.71 -2.1929 -0.9945 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C03 compound treatment 327930.0 -25600.0 -0.17 201200.0 -184000.0 -1.33 -1.0628 -0.7924 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C04 compound treatment 281180.0 -72300.0 -0.49 378830.0 -6120.0 -0.04 -0.377 -0.768 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C05 compound treatment 301760.0 -51800.0 -0.35 246250.0 -139000.0 -1.0 -0.9573 -0.9004 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C06 compound treatment 6890.0 -347000.0 -2.34 8000.0 -377000.0 -2.73 -3.5856 -0.9971 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C07 compound treatment 275790.0 -77700.0 -0.53 348480.0 -36500.0 -0.26 -0.5581 -0.9493 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C08 compound treatment 252870.0 -101000.0 -0.68 218960.0 -166000.0 -1.2 -1.3305 -0.9637 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C09 compound treatment 54580.0 -299000.0 -2.02 83050.0 -302000.0 -2.19 -2.9736 -0.9992 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C10 compound treatment 125050.0 -228000.0 -1.54 91770.0 -293000.0 -2.12 -2.5923 -0.9878 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C11 mock treatment 384700.0 31200.0 0.21 401080.0 16100.0 0.12 0.2315 0.9613 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C12 mock treatment 356960.0 3430.0 0.02 338900.0 -46000.0 -0.33 -0.2193 -0.6563 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C13 compound treatment 332480.0 -21000.0 -0.14 277770.0 -107000.0 -0.78 -0.6492 -0.823 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C14 compound treatment 50330.0 -303000.0 -2.05 57500.0 -327000.0 -2.37 -3.1247 -0.9974 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C15 mock treatment 311920.0 -41600.0 -0.28 281850.0 -103000.0 -0.75 -0.7265 -0.911 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C16 mock treatment 308960.0 -44600.0 -0.3 283380.0 -102000.0 -0.74 -0.7328 -0.9224 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C17 compound treatment 132970.0 -221000.0 -1.49 108530.0 -276000.0 -2.0 -2.4687 -0.9895 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C18 compound treatment 214850.0 -139000.0 -0.94 203000.0 -182000.0 -1.32 -1.5939 -0.9861 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C19 compound treatment 93440.0 -260000.0 -1.76 90180.0 -295000.0 -2.13 -2.7515 -0.9954 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C20 compound treatment 120120.0 -233000.0 -1.58 131240.0 -254000.0 -1.84 -2.4138 -0.9971 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C21 compound treatment 193330.0 -160000.0 -1.08 185300.0 -200000.0 -1.45 -1.7873 -0.9899 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C22 compound treatment 224650.0 -129000.0 -0.87 169690.0 -215000.0 -1.56 -1.7176 -0.9622 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C23 compound treatment 137280.0 -216000.0 -1.46 118760.0 -266000.0 -1.93 -2.3957 -0.9907 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 C24 compound treatment 194110.0 -159000.0 -1.08 189860.0 -195000.0 -1.41 -1.7602 -0.9911 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D01 compound treatment 284890.0 -68600.0 -0.46 325340.0 -59600.0 -0.43 -0.633 -0.9994 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D02 compound treatment 206600.0 -147000.0 -0.99 271680.0 -113000.0 -0.82 -1.2818 -0.9955 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D03 compound treatment 287680.0 -65800.0 -0.44 230790.0 -154000.0 -1.12 -1.1037 -0.9187 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D04 compound treatment 256650.0 -96900.0 -0.65 378720.0 -6230.0 -0.05 -0.4947 -0.754 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D05 compound treatment 261120.0 -92400.0 -0.62 266020.0 -119000.0 -0.86 -1.0502 -0.9876 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D06 compound treatment 256000.0 -97500.0 -0.66 291520.0 -93400.0 -0.68 -0.9442 -0.9999 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D07 compound treatment 283960.0 -69600.0 -0.47 346400.0 -38500.0 -0.28 -0.5297 -0.969 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D08 compound treatment 391840.0 38300.0 0.26 459300.0 74400.0 0.54 0.5636 0.9437 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D09 compound treatment 379840.0 26300.0 0.18 327400.0 -57500.0 -0.42 -0.1688 -0.3728 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D10 compound treatment 310400.0 -43100.0 -0.29 333700.0 -51200.0 -0.37 -0.4684 -0.9929 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D11 mock treatment 376720.0 23200.0 0.16 311710.0 -73200.0 -0.53 -0.2641 -0.4776 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D12 mock treatment 415420.0 61900.0 0.42 376070.0 -8880.0 -0.06 0.2503 0.5915 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D13 compound treatment 344020.0 -9510.0 -0.06 382260.0 -2690.0 -0.02 -0.0592 -0.8817 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D14 compound treatment 219060.0 -134000.0 -0.91 198660.0 -186000.0 -1.35 -1.596 -0.9815 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D15 mock treatment 310050.0 -43500.0 -0.29 360500.0 -24400.0 -0.18 -0.3329 -0.9706 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D16 mock treatment 363680.0 10200.0 0.07 392700.0 7750.0 0.06 0.0882 0.995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D17 compound treatment 281620.0 -71900.0 -0.49 276890.0 -108000.0 -0.78 -0.8967 -0.9738 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D18 compound treatment 275050.0 -78500.0 -0.53 328670.0 -56300.0 -0.41 -0.663 -0.9915 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D19 compound treatment 293620.0 -59900.0 -0.4 249240.0 -136000.0 -0.98 -0.9809 -0.9232 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D20 compound treatment 78270.0 -275000.0 -1.86 71430.0 -314000.0 -2.27 -2.9199 -0.9951 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D21 compound treatment 308960.0 -44600.0 -0.3 241860.0 -143000.0 -1.04 -0.9453 -0.8764 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D22 compound treatment 333940.0 -19600.0 -0.13 335520.0 -49400.0 -0.36 -0.3466 -0.9085 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D23 compound treatment 292010.0 -61500.0 -0.42 291490.0 -93500.0 -0.68 -0.7723 -0.9726 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 D24 compound treatment 318190.0 -35300.0 -0.24 289400.0 -95500.0 -0.69 -0.6579 -0.8991 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E01 mock treatment 300370.0 -53200.0 -0.36 486760.0 102000.0 0.74 0.2672 0.3259 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E02 mock treatment 415520.0 62000.0 0.42 409390.0 24400.0 0.18 0.4213 0.9265 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E03 compound treatment 246560.0 -107000.0 -0.72 246770.0 -138000.0 -1.0 -1.2183 -0.9873 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E04 compound treatment 219360.0 -134000.0 -0.91 147840.0 -237000.0 -1.72 -1.8547 -0.9555 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E05 compound treatment 274750.0 -78800.0 -0.53 220010.0 -165000.0 -1.19 -1.2206 -0.9338 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E06 compound treatment 279960.0 -73600.0 -0.5 328360.0 -56600.0 -0.41 -0.6411 -0.9954 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E07 compound treatment 186530.0 -167000.0 -1.13 212370.0 -173000.0 -1.25 -1.6812 -0.9987 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E08 compound treatment 163130.0 -190000.0 -1.29 187800.0 -197000.0 -1.43 -1.9188 -0.9987 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E09 mock treatment 337130.0 -16400.0 -0.11 473030.0 88100.0 0.64 0.3725 0.5756 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E10 mock treatment 342400.0 -11100.0 -0.08 468820.0 83900.0 0.61 0.3762 0.6149 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E11 compound treatment 276520.0 -77000.0 -0.52 294650.0 -90300.0 -0.65 -0.8301 -0.9936 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E12 compound treatment 235200.0 -118000.0 -0.8 208590.0 -176000.0 -1.28 -1.4681 -0.9746 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E13 compound treatment 298040.0 -55500.0 -0.37 307590.0 -77400.0 -0.56 -0.6611 -0.981 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E14 compound treatment 244990.0 -109000.0 -0.73 257600.0 -127000.0 -0.92 -1.1704 -0.9936 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E15 compound treatment 283520.0 -70000.0 -0.47 276430.0 -109000.0 -0.79 -0.8899 -0.9705 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E16 compound treatment 361820.0 8290.0 0.06 338960.0 -46000.0 -0.33 -0.1958 -0.5799 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E17 mock treatment 391840.0 38300.0 0.26 425150.0 40200.0 0.29 0.3888 0.9983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E18 mock treatment 396690.0 43200.0 0.29 363760.0 -21200.0 -0.15 0.0978 0.2967 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E19 compound treatment 318350.0 -35200.0 -0.24 244650.0 -140000.0 -1.02 -0.8862 -0.8496 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E20 compound treatment 260650.0 -92900.0 -0.63 280160.0 -105000.0 -0.76 -0.9801 -0.9956 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E21 compound treatment 186890.0 -167000.0 -1.13 200000.0 -185000.0 -1.34 -1.7428 -0.9963 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E22 compound treatment 214600.0 -139000.0 -0.94 234250.0 -151000.0 -1.09 -1.4351 -0.9972 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E23 compound treatment 177920.0 -176000.0 -1.19 186890.0 -198000.0 -1.43 -1.8528 -0.9956 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 E24 compound treatment 206920.0 -147000.0 -0.99 228190.0 -157000.0 -1.13 -1.5028 -0.9977 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F01 mock treatment 419360.0 65800.0 0.44 384480.0 -466.0 0.0 0.3122 0.7017 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F02 mock treatment 412320.0 58800.0 0.4 389600.0 4650.0 0.03 0.3047 0.7643 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F03 compound treatment 357440.0 3910.0 0.03 217070.0 -168000.0 -1.22 -0.8406 -0.6916 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F04 compound treatment 216580.0 -137000.0 -0.93 294170.0 -90800.0 -0.66 -1.119 -0.9859 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F05 compound treatment 324960.0 -28600.0 -0.19 328860.0 -56100.0 -0.41 -0.4236 -0.9422 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F06 compound treatment 91260.0 -262000.0 -1.77 134240.0 -251000.0 -1.81 -2.5363 -0.9999 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F07 compound treatment 194970.0 -159000.0 -1.07 206420.0 -179000.0 -1.29 -1.6714 -0.9957 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F08 compound treatment 374930.0 21400.0 0.14 336610.0 -48300.0 -0.35 -0.1452 -0.3834 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F09 mock treatment 440180.0 86700.0 0.59 319890.0 -65100.0 -0.47 0.081 0.1078 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F10 mock treatment 387150.0 33600.0 0.23 466520.0 81600.0 0.59 0.5782 0.9139 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F11 compound treatment 325120.0 -28400.0 -0.19 354980.0 -30000.0 -0.22 -0.2891 -0.9981 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F12 compound treatment 444710.0 91200.0 0.62 451070.0 66100.0 0.48 0.7741 0.9922 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F13 compound treatment 289950.0 -63600.0 -0.43 387640.0 2690.0 0.02 -0.29 -0.6743 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F14 compound treatment 350080.0 -3450.0 -0.02 346810.0 -38100.0 -0.28 -0.2117 -0.764 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F15 compound treatment 375530.0 22000.0 0.15 315700.0 -69200.0 -0.5 -0.2493 -0.4768 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F16 compound treatment 330950.0 -22600.0 -0.15 369220.0 -15700.0 -0.11 -0.1884 -0.9896 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F17 mock treatment 335520.0 -18000.0 -0.12 312040.0 -72900.0 -0.53 -0.4592 -0.8479 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F18 mock treatment 355680.0 2150.0 0.01 350340.0 -34600.0 -0.25 -0.1668 -0.6649 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F19 compound treatment 299470.0 -54100.0 -0.37 287620.0 -97300.0 -0.7 -0.7565 -0.9532 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F20 compound treatment 358160.0 4630.0 0.03 274120.0 -111000.0 -0.8 -0.5451 -0.679 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F21 compound treatment 309380.0 -44100.0 -0.3 323750.0 -61200.0 -0.44 -0.5242 -0.9815 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F22 compound treatment 198310.0 -155000.0 -1.05 247560.0 -137000.0 -0.99 -1.4448 -0.9996 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F23 compound treatment 303160.0 -50400.0 -0.34 365240.0 -19700.0 -0.14 -0.3415 -0.9255 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 F24 compound treatment 270200.0 -83300.0 -0.56 398930.0 14000.0 0.1 -0.3265 -0.5708 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G01 compound treatment 260510.0 -93000.0 -0.63 163840.0 -221000.0 -1.6 -1.5762 -0.9166 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G02 compound treatment 241790.0 -112000.0 -0.75 349820.0 -35100.0 -0.25 -0.7137 -0.8958 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G03 mock treatment 294580.0 -58900.0 -0.4 455890.0 70900.0 0.51 0.0815 0.1254 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G04 mock treatment 449620.0 96100.0 0.65 367640.0 -17300.0 -0.13 0.3705 0.5603 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G05 compound treatment 249760.0 -104000.0 -0.7 300660.0 -84300.0 -0.61 -0.9272 -0.9976 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G06 compound treatment 123060.0 -230000.0 -1.56 169890.0 -215000.0 -1.56 -2.2019 -1.0 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G07 compound treatment 235160.0 -118000.0 -0.8 294320.0 -90600.0 -0.66 -1.0294 -0.9952 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G08 compound treatment 304510.0 -49000.0 -0.33 278410.0 -107000.0 -0.77 -0.7795 -0.9288 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G09 compound treatment 144040.0 -209000.0 -1.42 120320.0 -265000.0 -1.92 -2.3554 -0.9889 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G10 compound treatment 324120.0 -29400.0 -0.2 291590.0 -93400.0 -0.68 -0.6184 -0.8778 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G11 compound treatment 120670.0 -233000.0 -1.57 188570.0 -196000.0 -1.42 -2.1177 -0.9987 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G12 compound treatment 228170.0 -125000.0 -0.85 335100.0 -49800.0 -0.36 -0.8541 -0.9277 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G13 compound treatment 218330.0 -135000.0 -0.91 207240.0 -178000.0 -1.29 -1.5556 -0.9859 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G14 compound treatment 162480.0 -191000.0 -1.29 127040.0 -258000.0 -1.87 -2.2329 -0.9838 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G15 compound treatment 213700.0 -140000.0 -0.94 232960.0 -152000.0 -1.1 -1.446 -0.9971 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G16 compound treatment 273000.0 -80500.0 -0.54 251420.0 -134000.0 -0.97 -1.0682 -0.963 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G17 compound treatment 171200.0 -182000.0 -1.23 224710.0 -160000.0 -1.16 -1.6913 -0.9995 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G18 compound treatment 311310.0 -42200.0 -0.29 362450.0 -22500.0 -0.16 -0.3169 -0.9647 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G19 mock treatment 327100.0 -26400.0 -0.18 346720.0 -38200.0 -0.28 -0.3219 -0.9775 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G20 mock treatment 306640.0 -46900.0 -0.32 393050.0 8100.0 0.06 -0.1825 -0.5665 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G21 compound treatment 187270.0 -166000.0 -1.12 226620.0 -158000.0 -1.15 -1.6048 -0.9999 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G22 compound treatment 196390.0 -157000.0 -1.06 184750.0 -200000.0 -1.45 -1.7755 -0.9883 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G23 compound treatment 264200.0 -89300.0 -0.6 240380.0 -145000.0 -1.05 -1.1668 -0.9658 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 G24 compound treatment 200830.0 -153000.0 -1.03 297980.0 -87000.0 -0.63 -1.1747 -0.9719 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H01 compound treatment 338400.0 -15100.0 -0.1 360750.0 -24200.0 -0.18 -0.1961 -0.9671 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H02 compound treatment 368220.0 14700.0 0.1 312000.0 -72900.0 -0.53 -0.3032 -0.5643 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H03 mock treatment 418190.0 64700.0 0.44 430320.0 45400.0 0.33 0.5412 0.9901 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H04 mock treatment 368080.0 14600.0 0.1 351090.0 -33900.0 -0.25 -0.1038 -0.3929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H05 compound treatment 213860.0 -140000.0 -0.94 320760.0 -64200.0 -0.46 -0.9958 -0.9467 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H06 compound treatment 229550.0 -124000.0 -0.84 317440.0 -67500.0 -0.49 -0.9379 -0.9671 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H07 compound treatment 312450.0 -41100.0 -0.28 394400.0 9450.0 0.07 -0.1479 -0.5173 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H08 compound treatment 270280.0 -83200.0 -0.56 261990.0 -123000.0 -0.89 -1.0271 -0.9755 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H09 compound treatment 370690.0 17200.0 0.12 377690.0 -7260.0 -0.05 0.0449 0.3524 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H10 compound treatment 103430.0 -250000.0 -1.69 110150.0 -275000.0 -1.99 -2.6015 -0.9967 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H11 compound treatment 233440.0 -120000.0 -0.81 283170.0 -102000.0 -0.74 -1.0947 -0.9988 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H12 compound treatment 212860.0 -141000.0 -0.95 264490.0 -120000.0 -0.87 -1.2887 -0.9991 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H13 compound treatment 317280.0 -36200.0 -0.24 363000.0 -21900.0 -0.16 -0.2855 -0.978 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H14 compound treatment 30950.0 -323000.0 -2.18 39910.0 -345000.0 -2.5 -3.3073 -0.9977 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H15 compound treatment 353360.0 -166.0 0.0 288380.0 -96600.0 -0.7 -0.4951 -0.7082 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H16 compound treatment 354100.0 574.0 0.0 301960.0 -83000.0 -0.6 -0.422 -0.7025 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H17 compound treatment 243860.0 -110000.0 -0.74 219540.0 -165000.0 -1.2 -1.3706 -0.9734 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H18 compound treatment 50720.0 -303000.0 -2.05 85310.0 -300000.0 -2.17 -2.9805 -0.9996 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H19 mock treatment 321290.0 -32200.0 -0.22 374360.0 -10600.0 -0.08 -0.2082 -0.9017 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H20 mock treatment 293650.0 -59900.0 -0.4 348160.0 -36800.0 -0.27 -0.4744 -0.9794 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H21 compound treatment 351320.0 -2210.0 -0.01 264610.0 -120000.0 -0.87 -0.6265 -0.7191 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H22 compound treatment 203650.0 -150000.0 -1.01 264580.0 -120000.0 -0.87 -1.3322 -0.9972 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H23 compound treatment 221820.0 -132000.0 -0.89 269710.0 -115000.0 -0.83 -1.2191 -0.9995 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 H24 compound treatment 271680.0 -81800.0 -0.55 419440.0 34500.0 0.25 -0.2145 -0.3535 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I01 compound treatment 178820.0 -175000.0 -1.18 266740.0 -118000.0 -0.86 -1.4398 -0.9875 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I02 compound treatment 174500.0 -179000.0 -1.21 184260.0 -201000.0 -1.45 -1.8826 -0.9959 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I03 compound treatment 191580.0 -162000.0 -1.09 282400.0 -103000.0 -0.74 -1.2987 -0.9821 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I04 compound treatment 49700.0 -304000.0 -2.05 63520.0 -321000.0 -2.33 -3.0969 -0.9981 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I05 mock treatment 274470.0 -79100.0 -0.53 362140.0 -22800.0 -0.17 -0.4945 -0.8844 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I06 mock treatment 328650.0 -24900.0 -0.17 352450.0 -32500.0 -0.24 -0.2852 -0.9864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I07 compound treatment 261620.0 -91900.0 -0.62 391160.0 6210.0 0.04 -0.4073 -0.6542 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I08 compound treatment 300980.0 -52500.0 -0.36 458880.0 73900.0 0.54 0.1274 0.1983 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I09 compound treatment 335430.0 -18100.0 -0.12 460000.0 75100.0 0.54 0.2977 0.5346 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I10 compound treatment 219210.0 -134000.0 -0.91 221400.0 -164000.0 -1.18 -1.4789 -0.9914 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I11 compound treatment 187880.0 -166000.0 -1.12 182780.0 -202000.0 -1.46 -1.8263 -0.9912 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I12 compound treatment 184430.0 -169000.0 -1.14 244320.0 -141000.0 -1.02 -1.5277 -0.9983 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I13 compound treatment 269290.0 -84200.0 -0.57 300710.0 -84200.0 -0.61 -0.8336 -0.9994 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I14 compound treatment 244900.0 -109000.0 -0.73 209390.0 -176000.0 -1.27 -1.4176 -0.966 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I15 compound treatment 253880.0 -99600.0 -0.67 301770.0 -83200.0 -0.6 -0.9018 -0.9984 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I16 compound treatment 223040.0 -130000.0 -0.88 218740.0 -166000.0 -1.2 -1.4742 -0.9883 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I17 compound treatment 174900.0 -179000.0 -1.21 220860.0 -164000.0 -1.19 -1.6933 -1.0 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I18 compound treatment 224290.0 -129000.0 -0.87 287690.0 -97300.0 -0.7 -1.1153 -0.9943 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I19 compound treatment 236170.0 -117000.0 -0.79 236320.0 -149000.0 -1.08 -1.3215 -0.9887 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I20 compound treatment 203960.0 -150000.0 -1.01 216850.0 -168000.0 -1.22 -1.575 -0.9957 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I21 mock treatment 225960.0 -128000.0 -0.86 405560.0 20600.0 0.15 -0.504 -0.5761 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I22 mock treatment 442660.0 89100.0 0.6 377210.0 -7740.0 -0.06 0.3863 0.6386 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I23 compound treatment 190690.0 -163000.0 -1.1 163680.0 -221000.0 -1.6 -1.9106 -0.9832 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 I24 compound treatment 115280.0 -238000.0 -1.61 141060.0 -244000.0 -1.77 -2.3867 -0.9989 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J01 compound treatment 262600.0 -90900.0 -0.61 295680.0 -89300.0 -0.65 -0.8914 -0.9997 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J02 compound treatment 264520.0 -89000.0 -0.6 366990.0 -18000.0 -0.13 -0.5172 -0.8405 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J03 compound treatment 200030.0 -153000.0 -1.04 237390.0 -148000.0 -1.07 -1.4887 -0.9999 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J04 compound treatment 309330.0 -44200.0 -0.3 394780.0 9830.0 0.07 -0.1608 -0.5239 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J05 mock treatment 319150.0 -34400.0 -0.23 383630.0 -1320.0 -0.01 -0.171 -0.7355 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J06 mock treatment 268700.0 -84800.0 -0.57 395530.0 10600.0 0.08 -0.3511 -0.6072 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J07 compound treatment 359930.0 6400.0 0.04 291270.0 -93700.0 -0.68 -0.4489 -0.6606 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J08 compound treatment 37310.0 -316000.0 -2.14 28440.0 -357000.0 -2.58 -3.3357 -0.9956 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J09 compound treatment 324660.0 -28900.0 -0.2 293020.0 -91900.0 -0.67 -0.6085 -0.8774 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J10 compound treatment 353210.0 -316.0 0.0 428640.0 43700.0 0.32 0.2221 0.7023 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J11 compound treatment 249410.0 -104000.0 -0.7 290300.0 -94600.0 -0.69 -0.9819 -0.9999 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J12 compound treatment 30410.0 -323000.0 -2.18 60960.0 -324000.0 -2.35 -3.2022 -0.9994 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J13 compound treatment 190910.0 -163000.0 -1.1 237040.0 -148000.0 -1.07 -1.534 -0.9999 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J14 compound treatment 336860.0 -16700.0 -0.11 422200.0 37300.0 0.27 0.1111 0.38 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J15 compound treatment 270170.0 -83400.0 -0.56 223200.0 -162000.0 -1.17 -1.2262 -0.9437 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J16 compound treatment 382750.0 29200.0 0.2 393880.0 8930.0 0.06 0.1854 0.8921 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J17 compound treatment 325200.0 -28300.0 -0.19 240010.0 -145000.0 -1.05 -0.8772 -0.8225 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J18 compound treatment 241680.0 -112000.0 -0.76 225940.0 -159000.0 -1.15 -1.3483 -0.9792 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J19 compound treatment 298430.0 -55100.0 -0.37 336680.0 -48300.0 -0.35 -0.5103 -0.9995 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J20 compound treatment 298930.0 -54600.0 -0.37 247000.0 -138000.0 -1.0 -0.967 -0.9083 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J21 mock treatment 317370.0 -36200.0 -0.24 381800.0 -3150.0 -0.02 -0.1889 -0.7697 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J22 mock treatment 295490.0 -58000.0 -0.39 374560.0 -10400.0 -0.08 -0.3304 -0.8276 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J23 compound treatment 208280.0 -145000.0 -0.98 246410.0 -139000.0 -1.0 -1.4031 -0.9999 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 J24 compound treatment 271770.0 -81800.0 -0.55 358270.0 -26700.0 -0.19 -0.5272 -0.9008 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K01 compound treatment 314450.0 -39100.0 -0.26 371360.0 -13600.0 -0.1 -0.2562 -0.9095 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K02 compound treatment 134080.0 -219000.0 -1.48 180560.0 -204000.0 -1.48 -2.0947 -1.0 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K03 compound treatment 350730.0 -2800.0 -0.02 347040.0 -37900.0 -0.27 -0.2074 -0.754 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K04 compound treatment 193450.0 -160000.0 -1.08 292230.0 -92700.0 -0.67 -1.2394 -0.9737 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K05 compound treatment 305300.0 -48200.0 -0.33 378180.0 -6770.0 -0.05 -0.265 -0.8044 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K06 compound treatment 19210.0 -334000.0 -2.26 49510.0 -335000.0 -2.43 -3.3143 -0.9993 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K07 mock treatment 345350.0 -8180.0 -0.06 411760.0 26800.0 0.19 0.0982 0.4865 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K08 mock treatment 337340.0 -16200.0 -0.11 487840.0 103000.0 0.74 0.4493 0.5969 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K09 compound treatment 386720.0 33200.0 0.22 478800.0 93900.0 0.68 0.639 0.8931 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K10 compound treatment 290340.0 -63200.0 -0.43 296330.0 -88600.0 -0.64 -0.7555 -0.9804 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K11 compound treatment 184000.0 -170000.0 -1.15 258030.0 -127000.0 -0.92 -1.4596 -0.994 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K12 compound treatment 183600.0 -170000.0 -1.15 259040.0 -126000.0 -0.91 -1.4563 -0.9935 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K13 compound treatment 273990.0 -79500.0 -0.54 427520.0 42600.0 0.31 -0.1621 -0.2616 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K14 compound treatment 201240.0 -152000.0 -1.03 187570.0 -197000.0 -1.43 -1.7379 -0.987 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K15 mock treatment 434670.0 81100.0 0.55 368380.0 -16600.0 -0.12 0.3029 0.5397 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K16 mock treatment 352220.0 -1310.0 -0.01 367120.0 -17800.0 -0.13 -0.0975 -0.7537 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K17 compound treatment 258610.0 -94900.0 -0.64 259680.0 -125000.0 -0.91 -1.0947 -0.9856 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K18 compound treatment 199230.0 -154000.0 -1.04 187640.0 -197000.0 -1.43 -1.7471 -0.988 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K19 compound treatment 231160.0 -122000.0 -0.83 234300.0 -151000.0 -1.09 -1.3558 -0.9907 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K20 compound treatment 232020.0 -122000.0 -0.82 205690.0 -179000.0 -1.3 -1.4981 -0.9756 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K21 compound treatment 202630.0 -151000.0 -1.02 252160.0 -133000.0 -0.96 -1.4006 -0.9996 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K22 compound treatment 235200.0 -118000.0 -0.8 170170.0 -215000.0 -1.55 -1.6647 -0.9522 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K23 mock treatment 452030.0 98500.0 0.67 237280.0 -148000.0 -1.07 -0.2852 -0.2265 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 K24 mock treatment 389150.0 35600.0 0.24 297920.0 -87000.0 -0.63 -0.2753 -0.4082 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L01 compound treatment 311380.0 -42100.0 -0.28 260600.0 -124000.0 -0.9 -0.8379 -0.8875 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L02 compound treatment 228390.0 -125000.0 -0.85 236370.0 -149000.0 -1.08 -1.3584 -0.9929 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L03 compound treatment 204090.0 -149000.0 -1.01 387710.0 2760.0 0.02 -0.6998 -0.693 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L04 compound treatment 323280.0 -30200.0 -0.2 357450.0 -27500.0 -0.2 -0.2853 -0.9999 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L05 compound treatment 230000.0 -124000.0 -0.83 273280.0 -112000.0 -0.81 -1.1618 -0.9999 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L06 compound treatment 206760.0 -147000.0 -0.99 347540.0 -37400.0 -0.27 -0.8927 -0.8684 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L07 mock treatment 366570.0 13000.0 0.09 385820.0 874.0 0.01 0.0668 0.7559 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L08 mock treatment 319770.0 -33800.0 -0.23 364860.0 -20100.0 -0.15 -0.2641 -0.9764 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L09 compound treatment 255610.0 -97900.0 -0.66 278530.0 -106000.0 -0.77 -1.0125 -0.9971 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L10 compound treatment 390030.0 36500.0 0.25 353760.0 -31200.0 -0.23 0.0148 0.0442 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L11 compound treatment 331560.0 -22000.0 -0.15 358600.0 -26300.0 -0.19 -0.2398 -0.9923 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L12 compound treatment 248710.0 -105000.0 -0.71 431360.0 46400.0 0.34 -0.2632 -0.3358 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L13 compound treatment 230640.0 -123000.0 -0.83 226680.0 -158000.0 -1.15 -1.3972 -0.9875 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L14 compound treatment 369170.0 15600.0 0.11 379920.0 -5030.0 -0.04 0.049 0.4385 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L15 mock treatment 447460.0 93900.0 0.63 507400.0 122000.0 0.89 1.0756 0.9866 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L16 mock treatment 326850.0 -26700.0 -0.18 450720.0 65800.0 0.48 0.2092 0.411 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L17 compound treatment 356660.0 3130.0 0.02 364850.0 -20100.0 -0.15 -0.0879 -0.5979 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L18 compound treatment 465070.0 112000.0 0.75 525390.0 140000.0 1.02 1.2518 0.9891 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L19 compound treatment 219320.0 -134000.0 -0.91 281770.0 -103000.0 -0.75 -1.1693 -0.9954 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L20 compound treatment 322400.0 -31100.0 -0.21 481360.0 96400.0 0.7 0.3448 0.473 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L21 compound treatment 355540.0 2010.0 0.01 384690.0 -256.0 0.0 0.0083 0.6051 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L22 compound treatment 398680.0 45200.0 0.31 417540.0 32600.0 0.24 0.3826 0.9919 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L23 mock treatment 363770.0 10200.0 0.07 304960.0 -80000.0 -0.58 -0.3605 -0.6182 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 L24 mock treatment 408640.0 55100.0 0.37 394080.0 9130.0 0.07 0.3101 0.8198 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M01 compound treatment 189510.0 -164000.0 -1.11 210730.0 -174000.0 -1.26 -1.6754 -0.9979 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M02 compound treatment 55900.0 -298000.0 -2.01 69280.0 -316000.0 -2.29 -3.0378 -0.998 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M03 compound treatment 200570.0 -153000.0 -1.03 183890.0 -201000.0 -1.46 -1.7599 -0.9859 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M04 compound treatment 212160.0 -141000.0 -0.96 246170.0 -139000.0 -1.0 -1.3858 -0.9997 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M05 compound treatment 77760.0 -276000.0 -1.86 118240.0 -267000.0 -1.93 -2.6827 -0.9998 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M06 compound treatment 85760.0 -268000.0 -1.81 72020.0 -313000.0 -2.27 -2.8811 -0.9938 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M07 compound treatment 225760.0 -128000.0 -0.86 203680.0 -181000.0 -1.31 -1.5383 -0.9794 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M08 compound treatment 198330.0 -155000.0 -1.05 218080.0 -167000.0 -1.21 -1.5956 -0.9975 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M09 mock treatment 335810.0 -17700.0 -0.12 461760.0 76800.0 0.56 0.3085 0.5425 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M10 mock treatment 431970.0 78400.0 0.53 414400.0 29500.0 0.21 0.5256 0.9199 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M11 compound treatment 339360.0 -14200.0 -0.1 321120.0 -63800.0 -0.46 -0.3944 -0.8358 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M12 compound treatment 328770.0 -24800.0 -0.17 263250.0 -122000.0 -0.88 -0.7412 -0.8266 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M13 mock treatment 303320.0 -50200.0 -0.34 389780.0 4830.0 0.03 -0.2151 -0.6308 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M14 mock treatment 373030.0 19500.0 0.13 485800.0 101000.0 0.73 0.6094 0.8215 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M15 compound treatment 210660.0 -143000.0 -0.97 289860.0 -95100.0 -0.69 -1.1693 -0.9863 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M16 compound treatment 266150.0 -87400.0 -0.59 272550.0 -112000.0 -0.81 -0.9928 -0.9876 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M17 compound treatment 166170.0 -187000.0 -1.27 139710.0 -245000.0 -1.78 -2.1504 -0.9863 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M18 compound treatment 231260.0 -122000.0 -0.83 243410.0 -142000.0 -1.02 -1.3086 -0.9943 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M19 compound treatment 252580.0 -101000.0 -0.68 309860.0 -75100.0 -0.54 -0.8666 -0.9937 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M20 compound treatment 194660.0 -159000.0 -1.07 246180.0 -139000.0 -1.0 -1.4693 -0.9995 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M21 compound treatment 170530.0 -183000.0 -1.24 180820.0 -204000.0 -1.48 -1.9192 -0.9961 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M22 compound treatment 255010.0 -98500.0 -0.67 254580.0 -130000.0 -0.94 -1.138 -0.9854 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M23 compound treatment 157140.0 -196000.0 -1.33 201760.0 -183000.0 -1.33 -1.876 -1.0 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 M24 compound treatment 161310.0 -192000.0 -1.3 175150.0 -210000.0 -1.52 -1.9923 -0.997 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N01 compound treatment 211870.0 -142000.0 -0.96 265820.0 -119000.0 -0.86 -1.2866 -0.9986 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N02 compound treatment 357810.0 4280.0 0.03 412590.0 27600.0 0.2 0.162 0.801 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N03 compound treatment 350560.0 -2970.0 -0.02 357090.0 -27900.0 -0.2 -0.1568 -0.7736 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N04 compound treatment 223060.0 -130000.0 -0.88 495390.0 110000.0 0.8 -0.058 -0.0487 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N05 compound treatment 228680.0 -125000.0 -0.84 222690.0 -162000.0 -1.17 -1.427 -0.9868 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N06 compound treatment 298790.0 -54700.0 -0.37 456130.0 71200.0 0.52 0.1028 0.1622 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N07 compound treatment 259420.0 -94100.0 -0.64 169710.0 -215000.0 -1.56 -1.5514 -0.9219 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N08 compound treatment 368230.0 14700.0 0.1 432480.0 47500.0 0.34 0.3136 0.8755 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N09 mock treatment 312880.0 -40600.0 -0.27 430300.0 45400.0 0.33 0.038 0.0887 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N10 mock treatment 357680.0 4150.0 0.03 423780.0 38800.0 0.28 0.2186 0.7739 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N11 compound treatment 292580.0 -60900.0 -0.41 297760.0 -87200.0 -0.63 -0.7375 -0.9786 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N12 compound treatment 234490.0 -119000.0 -0.8 234910.0 -150000.0 -1.09 -1.3367 -0.9891 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N13 mock treatment 384220.0 30700.0 0.21 456130.0 71200.0 0.52 0.511 0.92 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N14 mock treatment 342320.0 -11200.0 -0.08 474340.0 89400.0 0.65 0.404 0.6201 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N15 compound treatment 261120.0 -92400.0 -0.62 275290.0 -110000.0 -0.79 -1.0028 -0.9929 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N16 compound treatment 340860.0 -12700.0 -0.09 394810.0 9860.0 0.07 -0.01 -0.09 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N17 compound treatment 276860.0 -76700.0 -0.52 324770.0 -60200.0 -0.44 -0.6743 -0.9963 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N18 compound treatment 327520.0 -26000.0 -0.18 411150.0 26200.0 0.19 0.0099 0.0382 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N19 compound treatment 268270.0 -85300.0 -0.58 292680.0 -92300.0 -0.67 -0.8796 -0.9973 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N20 compound treatment 351550.0 -1980.0 -0.01 293290.0 -91700.0 -0.66 -0.4786 -0.7212 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N21 compound treatment 188090.0 -165000.0 -1.12 184190.0 -201000.0 -1.45 -1.818 -0.9916 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N22 compound treatment 230330.0 -123000.0 -0.83 208960.0 -176000.0 -1.27 -1.4894 -0.9787 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N23 compound treatment 236640.0 -117000.0 -0.79 287410.0 -97500.0 -0.71 -1.0577 -0.9984 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 N24 compound treatment 231610.0 -122000.0 -0.82 293010.0 -91900.0 -0.67 -1.0531 -0.9944 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O01 compound treatment 278110.0 -75400.0 -0.51 381130.0 -3820.0 -0.03 -0.3799 -0.7443 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O02 compound treatment 69990.0 -284000.0 -1.92 97080.0 -288000.0 -2.08 -2.8282 -0.9991 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O03 compound treatment 184090.0 -169000.0 -1.14 301290.0 -83700.0 -0.61 -1.2377 -0.9557 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O04 compound treatment 6030.0 -347000.0 -2.35 32390.0 -353000.0 -2.55 -3.4649 -0.9991 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O05 compound treatment 47010.0 -307000.0 -2.07 39280.0 -346000.0 -2.5 -3.2338 -0.9956 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O06 compound treatment 12770.0 -341000.0 -2.3 24210.0 -361000.0 -2.61 -3.4746 -0.998 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O07 compound treatment 190930.0 -163000.0 -1.1 180650.0 -204000.0 -1.48 -1.8226 -0.9893 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O08 compound treatment 166720.0 -187000.0 -1.26 150560.0 -234000.0 -1.7 -2.0923 -0.9894 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O09 compound treatment 180980.0 -173000.0 -1.17 210040.0 -175000.0 -1.27 -1.7197 -0.9992 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O10 compound treatment 165320.0 -188000.0 -1.27 157480.0 -227000.0 -1.65 -2.0635 -0.9918 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O11 mock treatment 286580.0 -66900.0 -0.45 355850.0 -29100.0 -0.21 -0.4688 -0.9395 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O12 mock treatment 379770.0 26200.0 0.18 306420.0 -78500.0 -0.57 -0.2766 -0.4645 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O13 compound treatment 174480.0 -179000.0 -1.21 161280.0 -224000.0 -1.62 -2.0003 -0.9897 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O14 compound treatment 196580.0 -157000.0 -1.06 210480.0 -174000.0 -1.26 -1.6429 -0.9962 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O15 compound treatment 94930.0 -259000.0 -1.75 86360.0 -299000.0 -2.16 -2.7639 -0.9944 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O16 compound treatment 183310.0 -170000.0 -1.15 192660.0 -192000.0 -1.39 -1.7975 -0.9955 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O17 compound treatment 246210.0 -107000.0 -0.73 161850.0 -223000.0 -1.61 -1.6547 -0.9347 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O18 compound treatment 167200.0 -186000.0 -1.26 135400.0 -250000.0 -1.81 -2.1676 -0.9844 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O19 compound treatment 175940.0 -178000.0 -1.2 196410.0 -189000.0 -1.36 -1.8135 -0.9979 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O20 compound treatment 177280.0 -176000.0 -1.19 189010.0 -196000.0 -1.42 -1.845 -0.9962 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O21 compound treatment 86080.0 -267000.0 -1.81 94620.0 -290000.0 -2.1 -2.7639 -0.9972 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O22 compound treatment 106120.0 -247000.0 -1.67 158360.0 -227000.0 -1.64 -2.3419 -1.0 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O23 compound treatment 157440.0 -196000.0 -1.32 160800.0 -224000.0 -1.62 -2.0842 -0.9949 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 O24 compound treatment 104830.0 -249000.0 -1.68 68640.0 -316000.0 -2.29 -2.8073 -0.9884 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P01 compound treatment 66750.0 -287000.0 -1.94 88160.0 -297000.0 -2.15 -2.8893 -0.9987 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P02 compound treatment 296030.0 -57500.0 -0.39 283200.0 -102000.0 -0.74 -0.7955 -0.9553 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P03 compound treatment 132450.0 -221000.0 -1.49 115850.0 -269000.0 -1.95 -2.4337 -0.9914 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P04 compound treatment 193770.0 -160000.0 -1.08 226000.0 -159000.0 -1.15 -1.5769 -0.9995 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P05 compound treatment 7640.0 -346000.0 -2.34 4380.0 -381000.0 -2.75 -3.6006 -0.9967 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P06 compound treatment 168280.0 -185000.0 -1.25 238160.0 -147000.0 -1.06 -1.6364 -0.9967 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P07 compound treatment 189930.0 -164000.0 -1.11 193780.0 -191000.0 -1.38 -1.7602 -0.9938 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P08 compound treatment 223490.0 -130000.0 -0.88 211950.0 -173000.0 -1.25 -1.5068 -0.985 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P09 compound treatment 140260.0 -213000.0 -1.44 181280.0 -204000.0 -1.47 -2.0614 -0.9999 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P10 compound treatment 223080.0 -130000.0 -0.88 198240.0 -187000.0 -1.35 -1.5789 -0.9785 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P11 mock treatment 270240.0 -83300.0 -0.56 286020.0 -98900.0 -0.72 -0.9043 -0.9929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P12 mock treatment 215890.0 -138000.0 -0.93 291640.0 -93300.0 -0.68 -1.1352 -0.9877 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P13 compound treatment 158630.0 -195000.0 -1.32 104270.0 -281000.0 -2.03 -2.3679 -0.978 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P14 compound treatment 273700.0 -79800.0 -0.54 229700.0 -155000.0 -1.12 -1.1761 -0.9434 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P15 compound treatment 144240.0 -209000.0 -1.41 204700.0 -180000.0 -1.3 -1.9226 -0.9992 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P16 compound treatment 198450.0 -155000.0 -1.05 220290.0 -165000.0 -1.19 -1.5837 -0.9979 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P17 compound treatment 171720.0 -182000.0 -1.23 185970.0 -199000.0 -1.44 -1.8871 -0.9969 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P18 compound treatment 126320.0 -227000.0 -1.54 207080.0 -178000.0 -1.29 -1.996 -0.9962 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P19 compound treatment 188080.0 -165000.0 -1.12 184820.0 -200000.0 -1.45 -1.8149 -0.9918 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P20 compound treatment 167420.0 -186000.0 -1.26 161220.0 -224000.0 -1.62 -2.0344 -0.9922 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P21 compound treatment 123240.0 -230000.0 -1.56 118160.0 -267000.0 -1.93 -2.4659 -0.9943 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P22 compound treatment 181240.0 -172000.0 -1.16 183540.0 -201000.0 -1.46 -1.8541 -0.9938 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P23 compound treatment 153890.0 -200000.0 -1.35 197030.0 -188000.0 -1.36 -1.9157 -1.0 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2102 P24 compound treatment 160580.0 -193000.0 -1.3 159160.0 -226000.0 -1.63 -2.0776 -0.9937 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A01 compound treatment 408160.0 12100.0 0.08 420050.0 4680.0 0.03 0.0819 0.9235 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A02 compound treatment 407650.0 11600.0 0.08 321380.0 -94000.0 -0.68 -0.4256 -0.6214 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A03 compound treatment 265410.0 -131000.0 -0.88 229490.0 -186000.0 -1.35 -1.5756 -0.9791 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A04 compound treatment 359600.0 -36400.0 -0.25 300830.0 -115000.0 -0.83 -0.7604 -0.8791 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A05 compound treatment 376030.0 -20000.0 -0.14 432240.0 16900.0 0.12 -0.0092 -0.0506 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A06 compound treatment 394080.0 -1950.0 -0.01 437830.0 22500.0 0.16 0.1056 0.6477 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A07 compound treatment 436730.0 40700.0 0.28 449850.0 34500.0 0.25 0.3709 0.9988 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A08 compound treatment 241770.0 -154000.0 -1.04 284110.0 -131000.0 -0.95 -1.4089 -0.9989 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A09 compound treatment 313630.0 -82400.0 -0.56 351960.0 -63400.0 -0.46 -0.7183 -0.9954 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A10 compound treatment 370790.0 -25200.0 -0.17 428560.0 13200.0 0.1 -0.0531 -0.2717 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A11 compound treatment 320490.0 -75500.0 -0.51 312640.0 -103000.0 -0.74 -0.8868 -0.9831 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A12 compound treatment 360440.0 -35600.0 -0.24 279140.0 -136000.0 -0.99 -0.8674 -0.8545 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A13 mock treatment 353210.0 -42800.0 -0.29 347230.0 -68100.0 -0.49 -0.5534 -0.9677 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A14 mock treatment 326180.0 -69900.0 -0.47 458790.0 43400.0 0.31 -0.1115 -0.1966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A15 compound treatment 319680.0 -76400.0 -0.52 343080.0 -72300.0 -0.52 -0.7348 -1.0 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A16 compound treatment 411520.0 15500.0 0.1 317970.0 -97400.0 -0.71 -0.4246 -0.5956 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A17 compound treatment 342830.0 -53200.0 -0.36 282180.0 -133000.0 -0.96 -0.936 -0.9096 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A18 compound treatment 431940.0 35900.0 0.24 326660.0 -88700.0 -0.64 -0.2825 -0.4115 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A19 compound treatment 329650.0 -66400.0 -0.45 321280.0 -94100.0 -0.68 -0.7988 -0.9795 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A20 compound treatment 382320.0 -13700.0 -0.09 310720.0 -105000.0 -0.76 -0.6012 -0.7877 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A21 compound treatment 297760.0 -98300.0 -0.66 263120.0 -152000.0 -1.1 -1.2489 -0.9706 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A22 compound treatment 349760.0 -46300.0 -0.31 397040.0 -18300.0 -0.13 -0.3149 -0.9272 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A23 compound treatment 364690.0 -31300.0 -0.21 481790.0 66400.0 0.48 0.1902 0.3621 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 A24 compound treatment 351440.0 -44600.0 -0.3 308810.0 -107000.0 -0.77 -0.7585 -0.9159 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B01 compound treatment 506430.0 110000.0 0.75 296560.0 -119000.0 -0.86 -0.0807 -0.0709 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B02 compound treatment 519560.0 124000.0 0.83 474510.0 59100.0 0.43 0.8929 0.9519 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B03 compound treatment 491440.0 95400.0 0.64 409210.0 -6160.0 -0.04 0.4243 0.6566 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B04 compound treatment 421070.0 25000.0 0.17 431700.0 16300.0 0.12 0.2032 0.9846 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B05 compound treatment 464740.0 68700.0 0.46 429920.0 14500.0 0.11 0.4027 0.846 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B06 compound treatment 407440.0 11400.0 0.08 436660.0 21300.0 0.15 0.1635 0.9488 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B07 compound treatment 484060.0 88000.0 0.59 461600.0 46200.0 0.33 0.6572 0.963 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B08 compound treatment 396490.0 460.0 0.0 411230.0 -4140.0 -0.03 -0.019 -0.6305 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B09 compound treatment 418740.0 22700.0 0.15 432860.0 17500.0 0.13 0.198 0.9954 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B10 compound treatment 466340.0 70300.0 0.48 365220.0 -50200.0 -0.36 0.0792 0.1325 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B11 compound treatment 367060.0 -29000.0 -0.2 385130.0 -30200.0 -0.22 -0.2932 -0.9984 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B12 compound treatment 512580.0 117000.0 0.79 392600.0 -22800.0 -0.16 0.4403 0.5472 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B13 mock treatment 394830.0 -1200.0 -0.01 434440.0 19100.0 0.14 0.0919 0.6644 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B14 mock treatment 363520.0 -32500.0 -0.22 402150.0 -13200.0 -0.1 -0.223 -0.9307 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B15 compound treatment 392320.0 -3710.0 -0.03 353220.0 -62200.0 -0.45 -0.3359 -0.7453 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B16 compound treatment 368160.0 -27900.0 -0.19 333000.0 -82400.0 -0.6 -0.5548 -0.8872 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B17 compound treatment 417060.0 21000.0 0.14 439590.0 24200.0 0.18 0.2244 0.9946 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B18 compound treatment 352870.0 -43200.0 -0.29 300050.0 -115000.0 -0.83 -0.7965 -0.9007 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B19 compound treatment 364000.0 -32000.0 -0.22 273030.0 -142000.0 -1.03 -0.8816 -0.8374 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B20 compound treatment 380970.0 -15100.0 -0.1 483360.0 68000.0 0.49 0.276 0.5493 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B21 compound treatment 448100.0 52100.0 0.35 423450.0 8080.0 0.06 0.2901 0.8135 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B22 compound treatment 291320.0 -105000.0 -0.71 288260.0 -127000.0 -0.92 -1.1509 -0.9916 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B23 compound treatment 363790.0 -32200.0 -0.22 383890.0 -31500.0 -0.23 -0.3152 -0.9997 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 B24 compound treatment 331130.0 -64900.0 -0.44 303450.0 -112000.0 -0.81 -0.883 -0.9584 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C01 compound treatment 368590.0 -27400.0 -0.19 331160.0 -84200.0 -0.61 -0.5622 -0.8823 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C02 compound treatment 393560.0 -2470.0 -0.02 360160.0 -55200.0 -0.4 -0.2944 -0.736 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C03 compound treatment 376160.0 -19900.0 -0.13 435120.0 19700.0 0.14 0.0061 0.0313 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C04 compound treatment 390280.0 -5750.0 -0.04 448610.0 33200.0 0.24 0.1427 0.5853 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C05 compound treatment 391320.0 -4710.0 -0.03 401760.0 -13600.0 -0.1 -0.0922 -0.8902 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C06 compound treatment 338490.0 -57500.0 -0.39 434080.0 18700.0 0.14 -0.1792 -0.4352 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C07 compound treatment 416530.0 20500.0 0.14 374770.0 -40600.0 -0.29 -0.1099 -0.3382 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C08 compound treatment 370560.0 -25500.0 -0.17 366850.0 -48500.0 -0.35 -0.3701 -0.9461 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C09 compound treatment 340420.0 -55600.0 -0.38 356380.0 -59000.0 -0.43 -0.5677 -0.998 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C10 compound treatment 334450.0 -61600.0 -0.42 337990.0 -77400.0 -0.56 -0.6903 -0.9893 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C11 mock treatment 415320.0 19300.0 0.13 389560.0 -25800.0 -0.19 -0.04 -0.1754 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C12 mock treatment 390570.0 -5460.0 -0.04 331010.0 -84400.0 -0.61 -0.4579 -0.7485 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C13 compound treatment 425040.0 29000.0 0.2 375640.0 -39700.0 -0.29 -0.0648 -0.1861 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C14 compound treatment 309890.0 -86100.0 -0.58 333060.0 -82300.0 -0.6 -0.8329 -0.9999 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C15 mock treatment 327600.0 -68400.0 -0.46 421440.0 6070.0 0.04 -0.2959 -0.6371 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C16 mock treatment 434170.0 38100.0 0.26 387110.0 -28300.0 -0.2 0.0376 0.1141 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C17 compound treatment 324980.0 -71100.0 -0.48 279380.0 -136000.0 -0.98 -1.0356 -0.9455 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C18 compound treatment 268980.0 -127000.0 -0.86 279560.0 -136000.0 -0.98 -1.3022 -0.9977 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C19 compound treatment 301380.0 -94700.0 -0.64 342800.0 -72600.0 -0.53 -0.8237 -0.9952 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C20 compound treatment 305360.0 -90700.0 -0.61 298880.0 -116000.0 -0.84 -1.0295 -0.9877 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C21 compound treatment 369870.0 -26200.0 -0.18 336730.0 -78600.0 -0.57 -0.5275 -0.885 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C22 compound treatment 336530.0 -59500.0 -0.4 394830.0 -20500.0 -0.15 -0.3894 -0.9085 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C23 compound treatment 272200.0 -124000.0 -0.84 340640.0 -74700.0 -0.54 -0.9742 -0.9777 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 C24 compound treatment 322040.0 -74000.0 -0.5 262610.0 -153000.0 -1.11 -1.1355 -0.9356 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D01 compound treatment 456590.0 60600.0 0.41 411810.0 -3560.0 -0.03 0.2711 0.6612 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D02 compound treatment 327480.0 -68600.0 -0.46 478370.0 63000.0 0.46 -0.0051 -0.0078 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D03 compound treatment 403810.0 7780.0 0.05 402940.0 -12400.0 -0.09 -0.0265 -0.254 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D04 compound treatment 328000.0 -68000.0 -0.46 331890.0 -83500.0 -0.6 -0.7524 -0.9909 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D05 compound treatment 492340.0 96300.0 0.65 474340.0 59000.0 0.43 0.762 0.9791 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D06 compound treatment 366470.0 -29600.0 -0.2 417390.0 2020.0 0.01 -0.1309 -0.6537 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D07 compound treatment 455620.0 59600.0 0.4 390510.0 -24900.0 -0.18 0.1574 0.357 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D08 compound treatment 353290.0 -42700.0 -0.29 480680.0 65300.0 0.47 0.1301 0.2348 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D09 compound treatment 417120.0 21100.0 0.14 342170.0 -73200.0 -0.53 -0.2739 -0.4992 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D10 compound treatment 459090.0 63100.0 0.43 462580.0 47200.0 0.34 0.5429 0.994 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D11 mock treatment 419530.0 23500.0 0.16 488730.0 73400.0 0.53 0.4878 0.88 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D12 mock treatment 414560.0 18500.0 0.13 454030.0 38700.0 0.28 0.2864 0.9342 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D13 compound treatment 493540.0 97500.0 0.66 421050.0 5680.0 0.04 0.4949 0.7498 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D14 compound treatment 400290.0 4260.0 0.03 418370.0 3000.0 0.02 0.0357 0.9903 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D15 mock treatment 383200.0 -12800.0 -0.09 303700.0 -112000.0 -0.81 -0.6329 -0.7785 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D16 mock treatment 460570.0 64500.0 0.44 406490.0 -8880.0 -0.06 0.2629 0.5964 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D17 compound treatment 402920.0 6890.0 0.05 375450.0 -39900.0 -0.29 -0.1714 -0.5857 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D18 compound treatment 294450.0 -102000.0 -0.69 365280.0 -50100.0 -0.36 -0.7417 -0.9555 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D19 compound treatment 378720.0 -17300.0 -0.12 388710.0 -26700.0 -0.19 -0.2192 -0.9712 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D20 compound treatment 386100.0 -9930.0 -0.07 327080.0 -88300.0 -0.64 -0.4994 -0.7771 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D21 compound treatment 435950.0 39900.0 0.27 407390.0 -7980.0 -0.06 0.1499 0.5433 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D22 compound treatment 413050.0 17000.0 0.12 336820.0 -78600.0 -0.57 -0.3208 -0.5529 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D23 compound treatment 345320.0 -50700.0 -0.34 389060.0 -26300.0 -0.19 -0.377 -0.9616 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 D24 compound treatment 414740.0 18700.0 0.13 269520.0 -146000.0 -1.06 -0.6572 -0.618 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E01 mock treatment 369120.0 -26900.0 -0.18 489940.0 74600.0 0.54 0.2531 0.4444 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E02 mock treatment 343120.0 -52900.0 -0.36 489700.0 74300.0 0.54 0.1277 0.1976 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E03 compound treatment 341020.0 -55000.0 -0.37 440410.0 25000.0 0.18 -0.1347 -0.3257 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E04 compound treatment 440700.0 44700.0 0.3 361220.0 -54200.0 -0.39 -0.0638 -0.1289 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E05 compound treatment 417550.0 21500.0 0.15 370310.0 -45100.0 -0.33 -0.1278 -0.358 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E06 compound treatment 276130.0 -120000.0 -0.81 514000.0 98600.0 0.71 -0.068 -0.063 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E07 compound treatment 353120.0 -42900.0 -0.29 465680.0 50300.0 0.36 0.0525 0.1128 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E08 compound treatment 428800.0 32800.0 0.22 500340.0 85000.0 0.62 0.5915 0.9048 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E09 mock treatment 456650.0 60600.0 0.41 503890.0 88500.0 0.64 0.7427 0.9766 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E10 mock treatment 390080.0 -5950.0 -0.04 528110.0 113000.0 0.82 0.5486 0.6715 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E11 compound treatment 456360.0 60300.0 0.41 445200.0 29800.0 0.22 0.4409 0.9558 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E12 compound treatment 406330.0 10300.0 0.07 369130.0 -46200.0 -0.33 -0.1875 -0.5484 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E13 compound treatment 466770.0 70700.0 0.48 347160.0 -68200.0 -0.49 -0.0112 -0.0163 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E14 compound treatment 400110.0 4080.0 0.03 411520.0 -3850.0 -0.03 -2.0E-4 -0.0059 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E15 compound treatment 393600.0 -2430.0 -0.02 409150.0 -6220.0 -0.05 -0.0435 -0.9065 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E16 compound treatment 239680.0 -156000.0 -1.06 178090.0 -237000.0 -1.72 -1.9616 -0.9727 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E17 mock treatment 314720.0 -81300.0 -0.55 370080.0 -45300.0 -0.33 -0.6203 -0.9696 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E18 mock treatment 353700.0 -42300.0 -0.29 475810.0 60400.0 0.44 0.1071 0.2049 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E19 compound treatment 418420.0 22400.0 0.15 301340.0 -114000.0 -0.83 -0.4767 -0.5681 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E20 compound treatment 438680.0 42600.0 0.29 341090.0 -74300.0 -0.54 -0.1765 -0.2892 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E21 compound treatment 296730.0 -99300.0 -0.67 286640.0 -129000.0 -0.93 -1.1334 -0.987 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E22 compound treatment 348080.0 -48000.0 -0.32 367460.0 -47900.0 -0.35 -0.4743 -0.9994 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E23 compound treatment 286830.0 -109000.0 -0.74 324160.0 -91200.0 -0.66 -0.9886 -0.9985 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 E24 compound treatment 320250.0 -75800.0 -0.51 308960.0 -106000.0 -0.77 -0.9068 -0.9803 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F01 mock treatment 447040.0 51000.0 0.34 385220.0 -30200.0 -0.22 0.0894 0.2191 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F02 mock treatment 318040.0 -78000.0 -0.53 447600.0 32200.0 0.23 -0.2077 -0.3603 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F03 compound treatment 561330.0 165000.0 1.12 440450.0 25100.0 0.18 0.9181 0.8114 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F04 compound treatment 463840.0 67800.0 0.46 388980.0 -26400.0 -0.19 0.1889 0.3805 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F05 compound treatment 506020.0 110000.0 0.74 459110.0 43700.0 0.32 0.7494 0.9277 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F06 compound treatment 359320.0 -36700.0 -0.25 304120.0 -111000.0 -0.81 -0.7449 -0.8839 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F07 compound treatment 412820.0 16800.0 0.11 448680.0 33300.0 0.24 0.2507 0.9409 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F08 compound treatment 495360.0 99300.0 0.67 479760.0 64400.0 0.47 0.8042 0.9841 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F09 mock treatment 465310.0 69300.0 0.47 480640.0 65300.0 0.47 0.6651 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F10 mock treatment 477020.0 81000.0 0.55 477170.0 61800.0 0.45 0.7033 0.995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F11 compound treatment 384830.0 -11200.0 -0.08 399080.0 -16300.0 -0.12 -0.1369 -0.977 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F12 compound treatment 393440.0 -2590.0 -0.02 406290.0 -9080.0 -0.07 -0.0589 -0.8652 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F13 compound treatment 431800.0 35800.0 0.24 390280.0 -25100.0 -0.18 0.0425 0.1404 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F14 compound treatment 444720.0 48700.0 0.33 326280.0 -89100.0 -0.64 -0.2234 -0.3086 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F15 compound treatment 411600.0 15600.0 0.11 459840.0 44500.0 0.32 0.302 0.8918 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F16 compound treatment 364890.0 -31100.0 -0.21 330200.0 -85200.0 -0.62 -0.5848 -0.8976 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F17 mock treatment 425140.0 29100.0 0.2 395690.0 -19700.0 -0.14 0.0383 0.1578 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F18 mock treatment 383200.0 -12800.0 -0.09 345440.0 -69900.0 -0.51 -0.4193 -0.8163 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F19 compound treatment 377700.0 -18300.0 -0.12 437600.0 22200.0 0.16 0.0262 0.129 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F20 compound treatment 346450.0 -49600.0 -0.34 373650.0 -41700.0 -0.3 -0.4505 -0.9987 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F21 compound treatment 334520.0 -61500.0 -0.42 371630.0 -43700.0 -0.32 -0.5178 -0.991 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F22 compound treatment 328410.0 -67600.0 -0.46 409000.0 -6370.0 -0.05 -0.3557 -0.7746 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F23 compound treatment 370780.0 -25300.0 -0.17 396160.0 -19200.0 -0.14 -0.219 -0.9949 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 F24 compound treatment 412430.0 16400.0 0.11 314920.0 -100000.0 -0.73 -0.4358 -0.5925 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G01 compound treatment 299420.0 -96600.0 -0.65 377310.0 -38100.0 -0.28 -0.6564 -0.9264 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G02 compound treatment 130280.0 -266000.0 -1.8 145460.0 -270000.0 -1.95 -2.6513 -0.9991 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G03 mock treatment 332410.0 -63600.0 -0.43 482880.0 67500.0 0.49 0.0416 0.0639 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G04 mock treatment 364590.0 -31400.0 -0.21 400370.0 -15000.0 -0.11 -0.227 -0.9515 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G05 compound treatment 425080.0 29000.0 0.2 473480.0 58100.0 0.42 0.4362 0.9398 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G06 compound treatment 456840.0 60800.0 0.41 405380.0 -9990.0 -0.07 0.2394 0.5738 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G07 compound treatment 478560.0 82500.0 0.56 390100.0 -25300.0 -0.18 0.2649 0.4514 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G08 compound treatment 438400.0 42400.0 0.29 465240.0 49900.0 0.36 0.4577 0.9934 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G09 compound treatment 473760.0 77700.0 0.53 473150.0 57800.0 0.42 0.6671 0.9936 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G10 compound treatment 438130.0 42100.0 0.28 489350.0 74000.0 0.54 0.5798 0.9562 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G11 compound treatment 298210.0 -97800.0 -0.66 369770.0 -45600.0 -0.33 -0.7008 -0.9485 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G12 compound treatment 427620.0 31600.0 0.21 256610.0 -159000.0 -1.15 -0.6617 -0.5661 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G13 compound treatment 220850.0 -175000.0 -1.18 346110.0 -69300.0 -0.5 -1.1915 -0.9269 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G14 compound treatment 229440.0 -167000.0 -1.13 428580.0 13200.0 0.1 -0.7283 -0.6447 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G15 compound treatment 326880.0 -69200.0 -0.47 350610.0 -64800.0 -0.47 -0.6619 -1.0 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G16 compound treatment 506960.0 111000.0 0.75 401400.0 -14000.0 -0.1 0.4585 0.6062 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G17 compound treatment 372960.0 -23100.0 -0.16 339090.0 -76300.0 -0.55 -0.5007 -0.8726 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G18 compound treatment 353570.0 -42500.0 -0.29 384520.0 -30900.0 -0.22 -0.3608 -0.9923 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G19 mock treatment 360000.0 -36000.0 -0.24 334760.0 -80600.0 -0.58 -0.5848 -0.9248 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G20 mock treatment 284180.0 -112000.0 -0.76 327280.0 -88100.0 -0.64 -0.9853 -0.9964 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G21 compound treatment 373820.0 -22200.0 -0.15 375680.0 -39700.0 -0.29 -0.3093 -0.9541 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G22 compound treatment 316200.0 -79800.0 -0.54 337000.0 -78400.0 -0.57 -0.7826 -0.9997 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G23 compound treatment 404250.0 8220.0 0.06 288190.0 -127000.0 -0.92 -0.6117 -0.6632 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 G24 compound treatment 294980.0 -101000.0 -0.68 256320.0 -159000.0 -1.15 -1.2969 -0.9689 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H01 compound treatment 470360.0 74300.0 0.5 420320.0 4950.0 0.04 0.3805 0.7556 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H02 compound treatment 429460.0 33400.0 0.23 536040.0 121000.0 0.87 0.7774 0.8616 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H03 mock treatment 323270.0 -72800.0 -0.49 409980.0 -5390.0 -0.04 -0.3752 -0.7609 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H04 mock treatment 488550.0 92500.0 0.63 521310.0 106000.0 0.77 0.9843 0.9949 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H05 compound treatment 516700.0 121000.0 0.82 532650.0 117000.0 0.85 1.1768 0.9998 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H06 compound treatment 397840.0 1810.0 0.01 376070.0 -39300.0 -0.28 -0.1925 -0.6761 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H07 compound treatment 514120.0 118000.0 0.8 413000.0 -2370.0 -0.02 0.5521 0.6917 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H08 compound treatment 535860.0 140000.0 0.94 420070.0 4700.0 0.03 0.6921 0.7321 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H09 compound treatment 452970.0 56900.0 0.38 457650.0 42300.0 0.31 0.4884 0.9936 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H10 compound treatment 400910.0 4880.0 0.03 476850.0 61500.0 0.45 0.338 0.7574 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H11 compound treatment 460060.0 64000.0 0.43 266130.0 -149000.0 -1.08 -0.458 -0.3936 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H12 compound treatment 348810.0 -47200.0 -0.32 466090.0 50700.0 0.37 0.034 0.0699 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H13 compound treatment 428090.0 32100.0 0.22 282130.0 -133000.0 -0.96 -0.5289 -0.535 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H14 compound treatment 281470.0 -115000.0 -0.77 399010.0 -16400.0 -0.12 -0.6311 -0.8059 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H15 compound treatment 345880.0 -50200.0 -0.34 446330.0 31000.0 0.22 -0.0811 -0.1998 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H16 compound treatment 345070.0 -51000.0 -0.34 331260.0 -84100.0 -0.61 -0.674 -0.9636 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H17 compound treatment 455200.0 59200.0 0.4 296890.0 -118000.0 -0.86 -0.3238 -0.3422 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H18 compound treatment 433400.0 37400.0 0.25 426570.0 11200.0 0.08 0.2359 0.8894 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H19 mock treatment 403290.0 7260.0 0.05 453480.0 38100.0 0.28 0.2297 0.82 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H20 mock treatment 400030.0 4000.0 0.03 464600.0 49200.0 0.36 0.2711 0.7586 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H21 compound treatment 310240.0 -85800.0 -0.58 340160.0 -75200.0 -0.54 -0.7949 -0.9995 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H22 compound treatment 346570.0 -49500.0 -0.33 323770.0 -91600.0 -0.66 -0.7052 -0.9497 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H23 compound treatment 328750.0 -67300.0 -0.45 405230.0 -10100.0 -0.07 -0.3734 -0.8108 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 H24 compound treatment 417760.0 21700.0 0.15 345250.0 -70100.0 -0.51 -0.2551 -0.4828 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I01 compound treatment 361250.0 -34800.0 -0.24 342240.0 -73100.0 -0.53 -0.5405 -0.9332 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I02 compound treatment 483470.0 87400.0 0.59 543610.0 128000.0 0.93 1.0742 0.9762 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I03 compound treatment 513330.0 117000.0 0.79 400290.0 -15100.0 -0.11 0.4832 0.604 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I04 compound treatment 403550.0 7520.0 0.05 456830.0 41500.0 0.3 0.2481 0.8152 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I05 mock treatment 525220.0 129000.0 0.87 454360.0 39000.0 0.28 0.8168 0.8903 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I06 mock treatment 443310.0 47300.0 0.32 487730.0 72400.0 0.52 0.5963 0.9719 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I07 compound treatment 442880.0 46800.0 0.32 395650.0 -19700.0 -0.14 0.1229 0.3539 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I08 compound treatment 338320.0 -57700.0 -0.39 387460.0 -27900.0 -0.2 -0.4186 -0.9532 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I09 compound treatment 424960.0 28900.0 0.2 450140.0 34800.0 0.25 0.3162 0.9922 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I10 compound treatment 454740.0 58700.0 0.4 443920.0 28500.0 0.21 0.4266 0.9538 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I11 compound treatment 461520.0 65500.0 0.44 501150.0 85800.0 0.62 0.752 0.9862 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I12 compound treatment 230750.0 -165000.0 -1.12 463040.0 47700.0 0.35 -0.5457 -0.4669 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I13 compound treatment 386360.0 -9670.0 -0.07 500530.0 85200.0 0.62 0.3897 0.6286 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I14 compound treatment 493120.0 97100.0 0.66 442100.0 26700.0 0.19 0.6007 0.8782 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I15 compound treatment 492800.0 96800.0 0.65 510620.0 95200.0 0.69 0.9499 0.9996 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I16 compound treatment 349530.0 -46500.0 -0.31 511430.0 96100.0 0.7 0.2695 0.3532 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I17 compound treatment 345700.0 -50300.0 -0.34 285130.0 -130000.0 -0.94 -0.9071 -0.9051 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I18 compound treatment 71530.0 -325000.0 -2.19 108370.0 -307000.0 -2.22 -3.1219 -1.0 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I19 compound treatment 307430.0 -88600.0 -0.6 414080.0 -1290.0 -0.01 -0.4299 -0.7181 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I20 compound treatment 325060.0 -71000.0 -0.48 306090.0 -109000.0 -0.79 -0.8985 -0.9712 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I21 mock treatment 276800.0 -119000.0 -0.81 346750.0 -68600.0 -0.5 -0.9209 -0.973 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I22 mock treatment 393530.0 -2500.0 -0.02 414720.0 -653.0 0.0 -0.0153 -0.8716 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I23 compound treatment 252020.0 -144000.0 -0.97 262660.0 -153000.0 -1.11 -1.4697 -0.998 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 I24 compound treatment 313120.0 -82900.0 -0.56 285960.0 -129000.0 -0.94 -1.0586 -0.9698 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J01 compound treatment 363560.0 -32500.0 -0.22 360640.0 -54700.0 -0.4 -0.4353 -0.9611 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J02 compound treatment 306990.0 -89000.0 -0.6 261760.0 -154000.0 -1.11 -1.2117 -0.9584 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J03 compound treatment 344160.0 -51900.0 -0.35 295540.0 -120000.0 -0.87 -0.8612 -0.9205 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J04 compound treatment 345920.0 -50100.0 -0.34 377940.0 -37400.0 -0.27 -0.431 -0.9939 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J05 mock treatment 406250.0 10200.0 0.07 326560.0 -88800.0 -0.64 -0.4058 -0.6275 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J06 mock treatment 445120.0 49100.0 0.33 430420.0 15000.0 0.11 0.3116 0.8924 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J07 compound treatment 521920.0 126000.0 0.85 452580.0 37200.0 0.27 0.7919 0.8876 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J08 compound treatment 258990.0 -137000.0 -0.93 300830.0 -115000.0 -0.83 -1.2411 -0.9985 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J09 compound treatment 489620.0 93600.0 0.63 450110.0 34700.0 0.25 0.625 0.9183 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J10 compound treatment 364220.0 -31800.0 -0.21 440400.0 25000.0 0.18 -0.0239 -0.0849 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J11 compound treatment 332000.0 -64000.0 -0.43 448160.0 32800.0 0.24 -0.1381 -0.2799 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J12 compound treatment 265040.0 -131000.0 -0.89 280480.0 -135000.0 -0.98 -1.3163 -0.9988 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J13 compound treatment 537160.0 141000.0 0.95 403080.0 -12300.0 -0.09 0.6114 0.6383 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J14 compound treatment 249710.0 -146000.0 -0.99 179440.0 -236000.0 -1.71 -1.9068 -0.9662 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J15 compound treatment 469210.0 73200.0 0.49 496830.0 81500.0 0.59 0.7666 0.9962 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J16 compound treatment 237240.0 -159000.0 -1.07 217870.0 -198000.0 -1.43 -1.7696 -0.99 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J17 compound treatment 352410.0 -43600.0 -0.29 296250.0 -119000.0 -0.86 -0.8182 -0.8978 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J18 compound treatment 194200.0 -202000.0 -1.36 264290.0 -151000.0 -1.09 -1.7377 -0.994 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J19 compound treatment 446500.0 50500.0 0.34 420290.0 4920.0 0.04 0.2663 0.7767 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J20 compound treatment 386840.0 -9190.0 -0.06 312770.0 -103000.0 -0.74 -0.5691 -0.7636 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J21 mock treatment 411710.0 15700.0 0.11 316070.0 -99300.0 -0.72 -0.4334 -0.5964 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J22 mock treatment 410190.0 14200.0 0.1 458240.0 42900.0 0.31 0.2871 0.8841 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J23 compound treatment 363960.0 -32100.0 -0.22 328990.0 -86400.0 -0.63 -0.5954 -0.8997 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 J24 compound treatment 320680.0 -75400.0 -0.51 311200.0 -104000.0 -0.75 -0.8932 -0.9817 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K01 compound treatment 263380.0 -133000.0 -0.9 390650.0 -24700.0 -0.18 -0.7603 -0.8319 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K02 compound treatment 239880.0 -156000.0 -1.06 246130.0 -169000.0 -1.23 -1.6124 -0.9972 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K03 compound treatment 335550.0 -60500.0 -0.41 324480.0 -90900.0 -0.66 -0.7542 -0.9738 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K04 compound treatment 461010.0 65000.0 0.44 456360.0 41000.0 0.3 0.5203 0.9818 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K05 compound treatment 318830.0 -77200.0 -0.52 442170.0 26800.0 0.19 -0.2317 -0.4163 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K06 compound treatment 408770.0 12700.0 0.09 375750.0 -39600.0 -0.29 -0.142 -0.474 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K07 mock treatment 556430.0 160000.0 1.08 432770.0 17400.0 0.13 0.8554 0.784 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K08 mock treatment 522720.0 127000.0 0.86 393170.0 -22200.0 -0.16 0.4916 0.5645 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K09 compound treatment 474580.0 78500.0 0.53 455860.0 40500.0 0.29 0.5825 0.9608 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K10 compound treatment 277950.0 -118000.0 -0.8 275910.0 -139000.0 -1.01 -1.278 -0.9932 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K11 compound treatment 366790.0 -29200.0 -0.2 446570.0 31200.0 0.23 0.02 0.0666 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K12 compound treatment 524700.0 129000.0 0.87 458890.0 43500.0 0.32 0.8375 0.9057 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K13 compound treatment 561920.0 166000.0 1.12 363420.0 -52000.0 -0.38 0.5267 0.4454 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K14 compound treatment 378880.0 -17200.0 -0.12 410210.0 -5160.0 -0.04 -0.1084 -0.89 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K15 mock treatment 478940.0 82900.0 0.56 434180.0 18800.0 0.14 0.4924 0.8541 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K16 mock treatment 433890.0 37900.0 0.26 490570.0 75200.0 0.54 0.5658 0.9407 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K17 compound treatment 381210.0 -14800.0 -0.1 429500.0 14100.0 0.1 0.0015 0.0105 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K18 compound treatment 348270.0 -47800.0 -0.32 516220.0 101000.0 0.73 0.288 0.3608 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K19 compound treatment 236540.0 -159000.0 -1.08 303910.0 -111000.0 -0.81 -1.3326 -0.9898 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K20 compound treatment 410950.0 14900.0 0.1 428530.0 13200.0 0.1 0.1386 0.9996 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K21 compound treatment 257860.0 -138000.0 -0.93 347690.0 -67700.0 -0.49 -1.0066 -0.9547 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K22 compound treatment 235620.0 -160000.0 -1.08 438560.0 23200.0 0.17 -0.6477 -0.5906 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K23 mock treatment 471920.0 75900.0 0.51 347520.0 -67900.0 -0.49 0.0153 0.0215 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 K24 mock treatment 495730.0 99700.0 0.67 412210.0 -3160.0 -0.02 0.4602 0.6827 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L01 compound treatment 400810.0 4780.0 0.03 456380.0 41000.0 0.3 0.2327 0.7794 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L02 compound treatment 478830.0 82800.0 0.56 521510.0 106000.0 0.77 0.9389 0.9879 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L03 compound treatment 382080.0 -14000.0 -0.09 465290.0 49900.0 0.36 0.1889 0.5057 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L04 compound treatment 273540.0 -122000.0 -0.83 337160.0 -78200.0 -0.57 -0.9856 -0.9829 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L05 compound treatment 420480.0 24400.0 0.17 496960.0 81600.0 0.59 0.5344 0.8714 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L06 compound treatment 467170.0 71100.0 0.48 430720.0 15300.0 0.11 0.4184 0.8482 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L07 mock treatment 518300.0 122000.0 0.83 453200.0 37800.0 0.27 0.7778 0.8937 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L08 mock treatment 383290.0 -12700.0 -0.09 402560.0 -12800.0 -0.09 -0.1265 -0.9993 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L09 compound treatment 499420.0 103000.0 0.7 552680.0 137000.0 0.99 1.1968 0.9851 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L10 compound treatment 285320.0 -111000.0 -0.75 377220.0 -38200.0 -0.28 -0.7242 -0.9083 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L11 compound treatment 503200.0 107000.0 0.72 481200.0 65800.0 0.48 0.849 0.9794 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L12 compound treatment 424000.0 28000.0 0.19 387120.0 -28300.0 -0.2 -0.011 -0.0394 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L13 compound treatment 225820.0 -170000.0 -1.15 503240.0 87900.0 0.64 -0.3635 -0.2766 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L14 compound treatment 253310.0 -143000.0 -0.96 395950.0 -19400.0 -0.14 -0.7813 -0.8017 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L15 mock treatment 432570.0 36500.0 0.25 452640.0 37300.0 0.27 0.3653 0.999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L16 mock treatment 437880.0 41800.0 0.28 537640.0 122000.0 0.89 0.8258 0.8888 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L17 compound treatment 439460.0 43400.0 0.29 421360.0 5990.0 0.04 0.2381 0.8028 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L18 compound treatment 226400.0 -170000.0 -1.15 290690.0 -125000.0 -0.9 -1.4487 -0.993 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L19 compound treatment 389040.0 -6990.0 -0.05 478400.0 63000.0 0.46 0.2892 0.6305 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L20 compound treatment 274650.0 -121000.0 -0.82 243280.0 -172000.0 -1.25 -1.4608 -0.9794 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L21 compound treatment 396480.0 450.0 0.0 450590.0 35200.0 0.25 0.1824 0.7155 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L22 compound treatment 250130.0 -146000.0 -0.99 277160.0 -138000.0 -1.0 -1.4046 -1.0 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L23 mock treatment 475860.0 79800.0 0.54 418560.0 3190.0 0.02 0.3977 0.7367 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 L24 mock treatment 352580.0 -43500.0 -0.29 449120.0 33700.0 0.24 -0.0349 -0.0913 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M01 compound treatment 357220.0 -38800.0 -0.26 420030.0 4660.0 0.03 -0.1616 -0.6112 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M02 compound treatment 382720.0 -13300.0 -0.09 435630.0 20300.0 0.15 0.0401 0.2331 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M03 compound treatment 366150.0 -29900.0 -0.2 467250.0 51900.0 0.38 0.1228 0.288 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M04 compound treatment 230590.0 -165000.0 -1.12 455110.0 39700.0 0.29 -0.587 -0.5086 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M05 compound treatment 275540.0 -120000.0 -0.81 422880.0 7510.0 0.05 -0.5373 -0.6584 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M06 compound treatment 251010.0 -145000.0 -0.98 310170.0 -105000.0 -0.76 -1.2314 -0.9922 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M07 compound treatment 520530.0 124000.0 0.84 501120.0 85700.0 0.62 1.0337 0.9888 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M08 compound treatment 271390.0 -125000.0 -0.84 484290.0 68900.0 0.5 -0.2427 -0.248 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M09 mock treatment 571200.0 175000.0 1.18 541010.0 126000.0 0.91 1.48 0.9915 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M10 mock treatment 436590.0 40600.0 0.27 535220.0 120000.0 0.87 0.8072 0.8873 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M11 compound treatment 424050.0 28000.0 0.19 498810.0 83400.0 0.6 0.561 0.8862 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M12 compound treatment 368580.0 -27500.0 -0.19 516400.0 101000.0 0.73 0.386 0.5116 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M13 mock treatment 445440.0 49400.0 0.33 451930.0 36600.0 0.26 0.4232 0.9934 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M14 mock treatment 387750.0 -8280.0 -0.06 495580.0 80200.0 0.58 0.371 0.636 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M15 compound treatment 327150.0 -68900.0 -0.47 293290.0 -122000.0 -0.88 -0.954 -0.9551 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M16 compound treatment 314560.0 -81500.0 -0.55 517150.0 102000.0 0.74 0.1317 0.1432 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M17 compound treatment 351520.0 -44500.0 -0.3 509400.0 94000.0 0.68 0.2686 0.361 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M18 compound treatment 350400.0 -45600.0 -0.31 414960.0 -413.0 0.0 -0.2201 -0.7139 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M19 mock treatment 430970.0 34900.0 0.24 571640.0 156000.0 1.13 0.9668 0.8367 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M20 compound treatment 383090.0 -12900.0 -0.09 342810.0 -72600.0 -0.53 -0.4333 -0.8136 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M21 mock treatment 403440.0 7410.0 0.05 315200.0 -100000.0 -0.73 -0.4774 -0.6567 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M22 compound treatment 326020.0 -70000.0 -0.47 369920.0 -45500.0 -0.33 -0.5672 -0.9843 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M23 mock treatment 407270.0 11200.0 0.08 404450.0 -10900.0 -0.08 -0.0022 -0.0202 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 M24 compound treatment 338510.0 -57500.0 -0.39 283530.0 -132000.0 -0.95 -0.9497 -0.9216 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N01 compound treatment 363690.0 -32300.0 -0.22 426120.0 10700.0 0.08 -0.0995 -0.429 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N02 compound treatment 324320.0 -71700.0 -0.48 381790.0 -33600.0 -0.24 -0.5145 -0.9491 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N03 compound treatment 515370.0 119000.0 0.81 314790.0 -101000.0 -0.73 0.0553 0.0509 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N04 compound treatment 332570.0 -63500.0 -0.43 265800.0 -150000.0 -1.08 -1.0688 -0.9178 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N05 compound treatment 445090.0 49100.0 0.33 478450.0 63100.0 0.46 0.5573 0.9876 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N06 compound treatment 553990.0 158000.0 1.07 422730.0 7360.0 0.05 0.7924 0.7415 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N07 compound treatment 510750.0 115000.0 0.78 497200.0 81800.0 0.59 0.967 0.9912 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N08 compound treatment 309610.0 -86400.0 -0.58 390600.0 -24800.0 -0.18 -0.5397 -0.8835 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N09 mock treatment 337860.0 -58200.0 -0.39 443860.0 28500.0 0.21 -0.1321 -0.2976 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N10 mock treatment 519630.0 124000.0 0.84 424100.0 8730.0 0.06 0.6352 0.7584 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N11 compound treatment 527650.0 132000.0 0.89 485490.0 70100.0 0.51 0.9878 0.9646 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N12 compound treatment 352340.0 -43700.0 -0.3 393930.0 -21400.0 -0.16 -0.3185 -0.9549 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N13 mock treatment 434430.0 38400.0 0.26 525560.0 110000.0 0.8 0.7475 0.8912 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N14 mock treatment 424320.0 28300.0 0.19 398760.0 -16600.0 -0.12 0.0501 0.222 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N15 compound treatment 363120.0 -32900.0 -0.22 456810.0 41400.0 0.3 0.0549 0.1469 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N16 compound treatment 466340.0 70300.0 0.48 496410.0 81000.0 0.59 0.7507 0.9945 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N17 compound treatment 413280.0 17200.0 0.12 355290.0 -60100.0 -0.43 -0.2251 -0.5 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N18 compound treatment 304420.0 -91600.0 -0.62 334740.0 -80600.0 -0.58 -0.8504 -0.9996 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N19 compound treatment 336030.0 -60000.0 -0.41 491430.0 76100.0 0.55 0.1026 0.1501 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N20 compound treatment 173600.0 -222000.0 -1.5 237950.0 -177000.0 -1.28 -1.9709 -0.9969 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N21 compound treatment 334330.0 -61700.0 -0.42 430440.0 15100.0 0.11 -0.2177 -0.5051 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N22 compound treatment 216770.0 -179000.0 -1.21 244320.0 -171000.0 -1.24 -1.732 -0.9999 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N23 compound treatment 396450.0 420.0 0.0 377340.0 -38000.0 -0.28 -0.1927 -0.6998 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 N24 compound treatment 222340.0 -174000.0 -1.17 272250.0 -143000.0 -1.04 -1.5625 -0.9981 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O01 mock treatment 463070.0 67000.0 0.45 397000.0 -18400.0 -0.13 0.2263 0.4793 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O02 compound treatment 351690.0 -44300.0 -0.3 399210.0 -16200.0 -0.12 -0.2946 -0.9159 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O03 mock treatment 334270.0 -61800.0 -0.42 450510.0 35100.0 0.25 -0.1152 -0.2358 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O04 mock treatment 355360.0 -40700.0 -0.27 408290.0 -7080.0 -0.05 -0.2306 -0.8248 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O05 mock treatment 304020.0 -92000.0 -0.62 361440.0 -53900.0 -0.39 -0.7157 -0.9749 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O06 mock treatment 399430.0 3400.0 0.02 433810.0 18400.0 0.13 0.1106 0.8168 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O07 mock treatment 323460.0 -72600.0 -0.49 414650.0 -723.0 -0.01 -0.3504 -0.7146 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O08 mock treatment 355870.0 -40200.0 -0.27 385290.0 -30100.0 -0.22 -0.3459 -0.9941 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O09 mock treatment 277920.0 -118000.0 -0.8 414940.0 -433.0 0.0 -0.5665 -0.7099 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O10 mock treatment 374270.0 -21800.0 -0.15 370920.0 -44500.0 -0.32 -0.3315 -0.937 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O11 mock treatment 477010.0 81000.0 0.55 394750.0 -20600.0 -0.15 0.2813 0.496 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O12 mock treatment 320170.0 -75900.0 -0.51 348060.0 -67300.0 -0.49 -0.707 -0.9997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O13 mock treatment 289380.0 -107000.0 -0.72 428100.0 12700.0 0.09 -0.4444 -0.6117 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O14 mock treatment 451270.0 55200.0 0.37 428410.0 13000.0 0.09 0.3307 0.8589 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O15 mock treatment 325080.0 -71000.0 -0.48 416540.0 1170.0 0.01 -0.333 -0.6945 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O16 mock treatment 458730.0 62700.0 0.42 297440.0 -118000.0 -0.85 -0.3041 -0.3191 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O17 mock treatment 366880.0 -29200.0 -0.2 395780.0 -19600.0 -0.14 -0.2396 -0.987 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O18 mock treatment 285530.0 -111000.0 -0.75 359210.0 -56200.0 -0.41 -0.8154 -0.9592 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O19 mock treatment 457810.0 61800.0 0.42 336260.0 -79100.0 -0.57 -0.1098 -0.1549 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O20 mock treatment 289070.0 -107000.0 -0.72 385540.0 -29800.0 -0.22 -0.6637 -0.88 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O21 mock treatment 329210.0 -66800.0 -0.45 299650.0 -116000.0 -0.84 -0.9116 -0.9579 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O22 mock treatment 282740.0 -113000.0 -0.77 269760.0 -146000.0 -1.05 -1.2866 -0.9877 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O23 mock treatment 369850.0 -26200.0 -0.18 363790.0 -51600.0 -0.37 -0.3891 -0.9418 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 O24 mock treatment 364210.0 -31800.0 -0.22 378400.0 -37000.0 -0.27 -0.3413 -0.9941 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P01 compound treatment 265370.0 -131000.0 -0.88 358150.0 -57200.0 -0.41 -0.9172 -0.9405 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P02 compound treatment 268980.0 -127000.0 -0.86 332580.0 -82800.0 -0.6 -1.0308 -0.9846 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P03 compound treatment 277350.0 -119000.0 -0.8 347450.0 -67900.0 -0.49 -0.9147 -0.9724 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P04 compound treatment 192060.0 -204000.0 -1.38 283880.0 -131000.0 -0.95 -1.6476 -0.9837 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P05 compound treatment 266090.0 -130000.0 -0.88 345620.0 -69800.0 -0.5 -0.9779 -0.9655 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P06 compound treatment 281390.0 -115000.0 -0.77 332800.0 -82600.0 -0.6 -0.9704 -0.9918 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P07 compound treatment 212160.0 -184000.0 -1.24 341280.0 -74100.0 -0.54 -1.2578 -0.9295 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P08 compound treatment 340800.0 -55200.0 -0.37 327530.0 -87800.0 -0.64 -0.7135 -0.9677 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P09 compound treatment 241280.0 -155000.0 -1.05 316020.0 -99400.0 -0.72 -1.2479 -0.9833 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P10 compound treatment 241440.0 -155000.0 -1.04 282370.0 -133000.0 -0.96 -1.4194 -0.9992 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P11 mock treatment 266180.0 -130000.0 -0.88 308340.0 -107000.0 -0.77 -1.1683 -0.9981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P12 mock treatment 276000.0 -120000.0 -0.81 331040.0 -84300.0 -0.61 -1.0052 -0.9902 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P13 compound treatment 244800.0 -151000.0 -1.02 270330.0 -145000.0 -1.05 -1.465 -0.9999 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P14 compound treatment 196870.0 -199000.0 -1.35 207160.0 -208000.0 -1.51 -2.0173 -0.9984 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P15 compound treatment 282240.0 -114000.0 -0.77 285190.0 -130000.0 -0.94 -1.21 -0.9949 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P16 compound treatment 212290.0 -184000.0 -1.24 282570.0 -133000.0 -0.96 -1.5577 -0.992 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P17 compound treatment 243690.0 -152000.0 -1.03 229930.0 -185000.0 -1.34 -1.6771 -0.9914 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P18 compound treatment 183110.0 -213000.0 -1.44 236120.0 -179000.0 -1.3 -1.9348 -0.9987 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P19 compound treatment 216550.0 -179000.0 -1.21 220480.0 -195000.0 -1.41 -1.8551 -0.9972 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P20 compound treatment 82170.0 -314000.0 -2.12 132410.0 -283000.0 -2.05 -2.948 -0.9998 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P21 compound treatment 248690.0 -147000.0 -1.0 214430.0 -201000.0 -1.45 -1.7325 -0.9829 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P22 compound treatment 187690.0 -208000.0 -1.41 174170.0 -241000.0 -1.75 -2.2301 -0.9943 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P23 compound treatment 250690.0 -145000.0 -0.98 171520.0 -244000.0 -1.77 -1.9426 -0.9617 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2130 P24 compound treatment 158760.0 -237000.0 -1.6 175930.0 -239000.0 -1.73 -2.3593 -0.9992 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A01 compound treatment 245540.0 -130000.0 -0.88 212320.0 -110000.0 -0.8 -1.1815 -0.9989 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A02 compound treatment 309090.0 -66000.0 -0.45 284700.0 -37500.0 -0.27 -0.5074 -0.9716 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A03 compound treatment 431970.0 56800.0 0.38 218190.0 -104000.0 -0.75 -0.2608 -0.3085 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A04 compound treatment 286120.0 -89000.0 -0.6 263100.0 -59100.0 -0.43 -0.7277 -0.9861 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A05 compound treatment 253540.0 -122000.0 -0.82 250520.0 -71700.0 -0.52 -0.9478 -0.9754 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A06 compound treatment 310620.0 -64500.0 -0.44 219160.0 -103000.0 -0.75 -0.8356 -0.9673 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A07 compound treatment 434350.0 59200.0 0.4 189350.0 -133000.0 -0.96 -0.397 -0.3812 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A08 compound treatment 401620.0 26500.0 0.18 251310.0 -70900.0 -0.51 -0.2362 -0.4347 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A09 compound treatment 354030.0 -21100.0 -0.14 301560.0 -20600.0 -0.15 -0.2064 -0.9997 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A10 compound treatment 351960.0 -23200.0 -0.16 281470.0 -40700.0 -0.29 -0.3191 -0.9561 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A11 compound treatment 309950.0 -65200.0 -0.44 286980.0 -35200.0 -0.25 -0.4916 -0.9662 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A12 compound treatment 291740.0 -83400.0 -0.56 255440.0 -66800.0 -0.48 -0.7401 -0.9971 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A13 mock treatment 373380.0 -1740.0 -0.01 345760.0 23600.0 0.17 0.1123 0.6567 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A14 mock treatment 360850.0 -14300.0 -0.1 321930.0 -265.0 0.0 -0.0695 -0.721 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A15 compound treatment 355840.0 -19300.0 -0.13 306130.0 -16100.0 -0.12 -0.1744 -0.9984 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A16 compound treatment 328420.0 -46700.0 -0.32 352690.0 30500.0 0.22 -0.067 -0.1741 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A17 compound treatment 384930.0 9810.0 0.07 316570.0 -5620.0 -0.04 0.0181 0.2323 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A18 compound treatment 365880.0 -9240.0 -0.06 353000.0 30800.0 0.22 0.1135 0.4902 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A19 compound treatment 354370.0 -20800.0 -0.14 254970.0 -67200.0 -0.49 -0.4433 -0.8753 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A20 compound treatment 345690.0 -29400.0 -0.2 353760.0 31600.0 0.23 0.0209 0.0691 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A21 compound treatment 261230.0 -114000.0 -0.77 236240.0 -86000.0 -0.62 -0.9841 -0.9944 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A22 compound treatment 351930.0 -23200.0 -0.16 271680.0 -50500.0 -0.37 -0.3694 -0.9285 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A23 compound treatment 308750.0 -66400.0 -0.45 297010.0 -25200.0 -0.18 -0.446 -0.9213 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 A24 compound treatment 278440.0 -96700.0 -0.65 304280.0 -17900.0 -0.13 -0.5536 -0.8313 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B01 compound treatment 317190.0 -57900.0 -0.39 424580.0 102000.0 0.74 0.2473 0.295 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B02 compound treatment 280680.0 -94400.0 -0.64 411520.0 89300.0 0.65 0.006 0.0066 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B03 compound treatment 224390.0 -151000.0 -1.02 323880.0 1690.0 0.01 -0.7115 -0.6986 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B04 compound treatment 421760.0 46600.0 0.32 283290.0 -38900.0 -0.28 0.0237 0.056 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B05 compound treatment 477160.0 102000.0 0.69 411840.0 89600.0 0.65 0.9464 0.9995 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B06 compound treatment 341920.0 -33200.0 -0.22 195100.0 -127000.0 -0.92 -0.8092 -0.8545 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B07 compound treatment 333300.0 -41800.0 -0.28 224530.0 -97700.0 -0.71 -0.6997 -0.919 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B08 compound treatment 198790.0 -176000.0 -1.19 228800.0 -93400.0 -0.68 -1.3205 -0.964 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B09 compound treatment 292640.0 -82500.0 -0.56 420760.0 98600.0 0.71 0.1104 0.122 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B10 compound treatment 458970.0 83800.0 0.57 240000.0 -82200.0 -0.6 -0.0201 -0.0245 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B11 compound treatment 451250.0 76100.0 0.51 360960.0 38800.0 0.28 0.5621 0.9594 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B12 compound treatment 153920.0 -221000.0 -1.49 184320.0 -138000.0 -1.0 -1.7626 -0.9807 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B13 mock treatment 323590.0 -51500.0 -0.35 338560.0 16400.0 0.12 -0.1624 -0.4417 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B14 mock treatment 295560.0 -79600.0 -0.54 321920.0 -275.0 0.0 -0.3815 -0.7097 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B15 compound treatment 262630.0 -112000.0 -0.76 249290.0 -72900.0 -0.53 -0.9106 -0.9841 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B16 compound treatment 9290.0 -366000.0 -2.47 7680.0 -315000.0 -2.28 -3.3578 -0.9992 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B17 compound treatment 294560.0 -80600.0 -0.54 246040.0 -76200.0 -0.55 -0.7747 -1.0 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B18 compound treatment 353290.0 -21800.0 -0.15 382720.0 60500.0 0.44 0.2055 0.4445 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B19 compound treatment 391380.0 16300.0 0.11 349320.0 27100.0 0.2 0.2165 0.9623 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B20 compound treatment 372380.0 -2740.0 -0.02 338140.0 15900.0 0.12 0.0685 0.586 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B21 compound treatment 361940.0 -13200.0 -0.09 347520.0 25300.0 0.18 0.0666 0.327 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B22 compound treatment 12410.0 -363000.0 -2.45 10250.0 -312000.0 -2.26 -3.3297 -0.9992 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B23 compound treatment 414720.0 39600.0 0.27 301440.0 -20800.0 -0.15 0.0829 0.2703 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 B24 compound treatment 46240.0 -329000.0 -2.22 49520.0 -273000.0 -1.97 -2.9671 -0.9983 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C01 compound treatment 305310.0 -69800.0 -0.47 223050.0 -99100.0 -0.72 -0.841 -0.9793 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C02 compound treatment 405790.0 30700.0 0.21 317440.0 -4750.0 -0.03 0.1222 0.5817 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C03 compound treatment 304180.0 -70900.0 -0.48 248960.0 -73200.0 -0.53 -0.7138 -0.9987 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C04 compound treatment 318210.0 -56900.0 -0.38 339250.0 17100.0 0.12 -0.1846 -0.4571 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C05 compound treatment 225520.0 -150000.0 -1.01 223040.0 -99200.0 -0.72 -1.2223 -0.9859 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C06 compound treatment 437920.0 62800.0 0.42 217250.0 -105000.0 -0.76 -0.2371 -0.2725 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C07 compound treatment 296560.0 -78600.0 -0.53 241360.0 -80800.0 -0.59 -0.7891 -0.9988 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C08 compound treatment 366240.0 -8880.0 -0.06 301570.0 -20600.0 -0.15 -0.148 -0.9198 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C09 compound treatment 298930.0 -76200.0 -0.51 279150.0 -43000.0 -0.31 -0.5844 -0.9711 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C10 compound treatment 320120.0 -55000.0 -0.37 306520.0 -15700.0 -0.11 -0.343 -0.8828 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C11 mock treatment 355360.0 -19800.0 -0.13 242350.0 -79800.0 -0.58 -0.5031 -0.8481 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C12 mock treatment 336480.0 -38600.0 -0.26 335570.0 13400.0 0.1 -0.1162 -0.4171 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C13 compound treatment 360640.0 -14500.0 -0.1 392680.0 70500.0 0.51 0.2916 0.5613 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C14 compound treatment 336690.0 -38400.0 -0.26 287470.0 -34700.0 -0.25 -0.3614 -0.9999 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C15 mock treatment 375260.0 137.0 0.0 296560.0 -25600.0 -0.19 -0.1306 -0.7036 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C16 mock treatment 302630.0 -72500.0 -0.49 235240.0 -87000.0 -0.63 -0.7915 -0.9923 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C17 compound treatment 336580.0 -38500.0 -0.26 269150.0 -53000.0 -0.38 -0.4557 -0.9821 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C18 compound treatment 322240.0 -52900.0 -0.36 262720.0 -59500.0 -0.43 -0.5571 -0.9957 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C19 compound treatment 341870.0 -33300.0 -0.22 257440.0 -64800.0 -0.47 -0.4903 -0.9433 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C20 compound treatment 292770.0 -82400.0 -0.56 278600.0 -43600.0 -0.32 -0.6166 -0.9639 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C21 compound treatment 365770.0 -9350.0 -0.06 268730.0 -53500.0 -0.39 -0.3184 -0.8118 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C22 compound treatment 311680.0 -63400.0 -0.43 259200.0 -63000.0 -0.46 -0.6256 -0.9995 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C23 compound treatment 353360.0 -21800.0 -0.15 318610.0 -3580.0 -0.03 -0.1223 -0.8192 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 C24 compound treatment 306820.0 -68300.0 -0.46 282780.0 -39400.0 -0.29 -0.5281 -0.9733 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D01 compound treatment 215580.0 -160000.0 -1.08 346560.0 24400.0 0.18 -0.6375 -0.5837 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D02 compound treatment 425160.0 50000.0 0.34 347600.0 25400.0 0.18 0.3691 0.959 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D03 compound treatment 265340.0 -110000.0 -0.74 394880.0 72700.0 0.53 -0.1525 -0.1676 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D04 compound treatment 339770.0 -35400.0 -0.24 245660.0 -76500.0 -0.55 -0.5607 -0.9293 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D05 compound treatment 208880.0 -166000.0 -1.12 193600.0 -129000.0 -0.93 -1.4525 -0.9956 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D06 compound treatment 301440.0 -73700.0 -0.5 424720.0 103000.0 0.74 0.1728 0.1933 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D07 compound treatment 402120.0 27000.0 0.18 268010.0 -54200.0 -0.39 -0.1484 -0.343 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D08 compound treatment 316830.0 -58300.0 -0.39 331290.0 9100.0 0.07 -0.232 -0.5808 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D09 compound treatment 364330.0 -10800.0 -0.07 263840.0 -58400.0 -0.42 -0.3503 -0.8171 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D10 compound treatment 420800.0 45700.0 0.31 292510.0 -29700.0 -0.21 0.0663 0.1763 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D11 mock treatment 368880.0 -6240.0 -0.04 317920.0 -4270.0 -0.03 -0.0517 -0.9884 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D12 mock treatment 349120.0 -26000.0 -0.18 258650.0 -63500.0 -0.46 -0.4495 -0.9129 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D13 compound treatment 472000.0 96900.0 0.65 352730.0 30500.0 0.22 0.6192 0.8962 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D14 compound treatment 374250.0 -873.0 -0.01 305920.0 -16300.0 -0.12 -0.0875 -0.7416 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D15 mock treatment 355560.0 -19600.0 -0.13 296290.0 -25900.0 -0.19 -0.2261 -0.9853 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D16 mock treatment 366720.0 -8400.0 -0.06 329080.0 6890.0 0.05 -0.0049 -0.0649 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D17 compound treatment 405670.0 30500.0 0.21 317640.0 -4550.0 -0.03 0.1226 0.5867 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D18 compound treatment 343260.0 -31900.0 -0.22 302600.0 -19600.0 -0.14 -0.2525 -0.9795 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D19 compound treatment 372390.0 -2730.0 -0.02 315780.0 -6410.0 -0.05 -0.0459 -0.9184 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D20 compound treatment 359430.0 -15700.0 -0.11 307840.0 -14400.0 -0.1 -0.1485 -0.9999 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D21 compound treatment 400850.0 25700.0 0.17 311200.0 -11000.0 -0.08 0.0666 0.3486 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D22 compound treatment 392070.0 16900.0 0.11 289170.0 -33000.0 -0.24 -0.0881 -0.3323 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D23 compound treatment 310210.0 -64900.0 -0.44 293000.0 -29200.0 -0.21 -0.4596 -0.944 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 D24 compound treatment 307710.0 -67400.0 -0.46 242690.0 -79500.0 -0.58 -0.729 -0.9933 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E01 mock treatment 326360.0 -48800.0 -0.33 266990.0 -55200.0 -0.4 -0.5156 -0.9954 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E02 mock treatment 350080.0 -25000.0 -0.17 335120.0 12900.0 0.09 -0.0535 -0.2766 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E03 compound treatment 284450.0 -90700.0 -0.61 393760.0 71600.0 0.52 -0.0669 -0.0834 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E04 compound treatment 292680.0 -82400.0 -0.56 246200.0 -76000.0 -0.55 -0.7829 -1.0 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E05 compound treatment 411360.0 36200.0 0.24 267940.0 -54300.0 -0.39 -0.1046 -0.226 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E06 compound treatment 308230.0 -66900.0 -0.45 284220.0 -38000.0 -0.27 -0.514 -0.9716 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E07 compound treatment 317810.0 -57300.0 -0.39 245630.0 -76600.0 -0.55 -0.6657 -0.9846 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E08 compound treatment 362660.0 -12500.0 -0.08 321180.0 -1010.0 -0.01 -0.0647 -0.7659 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E09 mock treatment 340020.0 -35100.0 -0.24 304200.0 -18000.0 -0.13 -0.2598 -0.9602 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E10 mock treatment 416320.0 41200.0 0.28 377050.0 54900.0 0.4 0.4776 0.9849 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E11 compound treatment 310280.0 -64800.0 -0.44 300930.0 -21300.0 -0.15 -0.4187 -0.9015 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E12 compound treatment 419570.0 44400.0 0.3 360770.0 38600.0 0.28 0.4098 0.9993 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E13 compound treatment 377170.0 2050.0 0.01 334410.0 12200.0 0.09 0.0723 0.8079 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E14 compound treatment 361990.0 -13100.0 -0.09 328080.0 5890.0 0.04 -0.0326 -0.3314 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E15 compound treatment 361340.0 -13800.0 -0.09 338600.0 16400.0 0.12 0.0181 0.1201 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E16 compound treatment 385930.0 10800.0 0.07 314310.0 -7880.0 -0.06 0.0113 0.1216 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E17 mock treatment 419120.0 44000.0 0.3 276760.0 -45400.0 -0.33 -0.0224 -0.0504 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E18 mock treatment 405930.0 30800.0 0.21 341920.0 19700.0 0.14 0.2482 0.9831 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E19 compound treatment 377120.0 2000.0 0.01 358360.0 36200.0 0.26 0.1947 0.7426 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E20 compound treatment 378650.0 3530.0 0.02 317600.0 -4590.0 -0.03 -0.0067 -0.163 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E21 compound treatment 353920.0 -21200.0 -0.14 297190.0 -25000.0 -0.18 -0.2293 -0.9933 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E22 compound treatment 407470.0 32300.0 0.22 314330.0 -7860.0 -0.06 0.1143 0.506 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E23 compound treatment 378780.0 3660.0 0.02 327560.0 5370.0 0.04 0.0449 0.9762 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 E24 compound treatment 424010.0 48900.0 0.33 323290.0 1100.0 0.01 0.2392 0.7239 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F01 mock treatment 369660.0 -5460.0 -0.04 282580.0 -39600.0 -0.29 -0.2289 -0.7916 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F02 mock treatment 329070.0 -46100.0 -0.31 262360.0 -59800.0 -0.43 -0.5263 -0.9868 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F03 compound treatment 244050.0 -131000.0 -0.89 313920.0 -8270.0 -0.06 -0.6686 -0.7532 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F04 compound treatment 371610.0 -3510.0 -0.02 337310.0 15100.0 0.11 0.0606 0.5411 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F05 compound treatment 177190.0 -198000.0 -1.34 248900.0 -73300.0 -0.53 -1.3209 -0.918 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F06 compound treatment 383770.0 8650.0 0.06 250580.0 -71600.0 -0.52 -0.3253 -0.6235 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F07 compound treatment 434720.0 59600.0 0.4 345960.0 23800.0 0.17 0.4064 0.9281 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F08 compound treatment 381390.0 6270.0 0.04 260900.0 -61300.0 -0.44 -0.2838 -0.6367 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F09 mock treatment 329510.0 -45600.0 -0.31 303260.0 -18900.0 -0.14 -0.3149 -0.9334 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F10 mock treatment 468090.0 93000.0 0.63 342810.0 20600.0 0.15 0.5497 0.8514 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F11 compound treatment 397350.0 22200.0 0.15 341600.0 19400.0 0.14 0.2055 0.9994 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F12 compound treatment 299250.0 -75900.0 -0.51 218140.0 -104000.0 -0.75 -0.8951 -0.9824 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F13 compound treatment 244690.0 -130000.0 -0.88 212770.0 -109000.0 -0.79 -1.1833 -0.9986 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F14 compound treatment 350800.0 -24300.0 -0.16 344020.0 21800.0 0.16 -0.0045 -0.0197 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F15 compound treatment 410760.0 35600.0 0.24 381630.0 59400.0 0.43 0.4745 0.9624 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F16 compound treatment 454490.0 79400.0 0.54 305120.0 -17100.0 -0.12 0.2918 0.5302 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F17 mock treatment 395520.0 20400.0 0.14 353500.0 31300.0 0.23 0.2577 0.9716 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F18 mock treatment 403560.0 28400.0 0.19 421530.0 99300.0 0.72 0.6443 0.8657 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F19 compound treatment 359010.0 -16100.0 -0.11 329490.0 7300.0 0.05 -0.0396 -0.3276 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F20 compound treatment 124230.0 -251000.0 -1.7 109550.0 -213000.0 -1.54 -2.2872 -0.9988 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F21 compound treatment 414640.0 39500.0 0.27 345390.0 23200.0 0.17 0.3075 0.975 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F22 compound treatment 437300.0 62200.0 0.42 369440.0 47200.0 0.34 0.5389 0.9948 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F23 compound treatment 372640.0 -2480.0 -0.02 303880.0 -18300.0 -0.13 -0.1056 -0.7903 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 F24 compound treatment 395270.0 20100.0 0.14 350240.0 28000.0 0.2 0.2398 0.9811 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G01 compound treatment 343000.0 -32100.0 -0.22 306320.0 -15900.0 -0.11 -0.2347 -0.9558 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G02 compound treatment 298740.0 -76400.0 -0.52 359310.0 37100.0 0.27 -0.175 -0.3007 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G03 mock treatment 400930.0 25800.0 0.17 368960.0 46800.0 0.34 0.3627 0.9524 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G04 mock treatment 455770.0 80600.0 0.54 342990.0 20800.0 0.15 0.4918 0.8699 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G05 compound treatment 340030.0 -35100.0 -0.24 326400.0 4210.0 0.03 -0.1461 -0.6113 PK04_181123 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G06 compound treatment 456040.0 80900.0 0.55 444210.0 122000.0 0.88 1.0112 0.9734 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G07 compound treatment 349950.0 -25200.0 -0.17 365800.0 43600.0 0.32 0.1029 0.2871 PK04_181125 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G08 compound treatment 421250.0 46100.0 0.31 289000.0 -33200.0 -0.24 0.0505 0.1282 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G09 compound treatment 341530.0 -33600.0 -0.23 276700.0 -45500.0 -0.33 -0.3934 -0.9835 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G10 compound treatment 447320.0 72200.0 0.49 348720.0 26500.0 0.19 0.4807 0.917 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G11 compound treatment 392740.0 17600.0 0.12 319630.0 -2560.0 -0.02 0.071 0.5897 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G12 compound treatment 271680.0 -103000.0 -0.7 156400.0 -166000.0 -1.2 -1.3429 -0.9669 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G13 compound treatment 320220.0 -54900.0 -0.37 253960.0 -68200.0 -0.49 -0.6116 -0.99 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G14 compound treatment 368680.0 -6440.0 -0.04 328590.0 6400.0 0.05 0.002 0.0307 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G15 compound treatment 359700.0 -15400.0 -0.1 286320.0 -35900.0 -0.26 -0.2573 -0.9196 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G16 compound treatment 394420.0 19300.0 0.13 284010.0 -38200.0 -0.28 -0.1033 -0.3379 3561954 PK04_181134 COc1ccccc1/C=C/CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G17 compound treatment 372720.0 -2400.0 -0.02 341700.0 19500.0 0.14 0.0884 0.6217 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G18 compound treatment 385460.0 10300.0 0.07 344960.0 22800.0 0.16 0.1659 0.927 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G19 mock treatment 405570.0 30400.0 0.21 329660.0 7470.0 0.05 0.1837 0.8636 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G20 mock treatment 455360.0 80200.0 0.54 317280.0 -4910.0 -0.04 0.3582 0.6593 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G21 compound treatment 394940.0 19800.0 0.13 340360.0 18200.0 0.13 0.1877 1.0 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G22 compound treatment 371310.0 -3810.0 -0.03 292560.0 -29600.0 -0.21 -0.1699 -0.7864 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G23 compound treatment 273200.0 -102000.0 -0.69 278270.0 -43900.0 -0.32 -0.7118 -0.9384 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 G24 compound treatment 368890.0 -6230.0 -0.04 341040.0 18800.0 0.14 0.0667 0.467 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H01 compound treatment 355140.0 -20000.0 -0.14 380370.0 58200.0 0.42 0.2023 0.4575 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H02 compound treatment 357020.0 -18100.0 -0.12 280290.0 -41900.0 -0.3 -0.301 -0.9202 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H03 mock treatment 367000.0 -8120.0 -0.05 344020.0 21800.0 0.16 0.0729 0.4359 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H04 mock treatment 449200.0 74100.0 0.5 239690.0 -82500.0 -0.6 -0.0684 -0.0878 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H05 compound treatment 388050.0 12900.0 0.09 253600.0 -68600.0 -0.5 -0.2894 -0.5739 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H06 compound treatment 350470.0 -24700.0 -0.17 397940.0 75700.0 0.55 0.2699 0.471 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H07 compound treatment 434560.0 59400.0 0.4 379070.0 56900.0 0.41 0.5751 0.9999 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H08 compound treatment 311620.0 -63500.0 -0.43 387150.0 65000.0 0.47 0.0291 0.0457 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H09 compound treatment 408860.0 33700.0 0.23 373640.0 51400.0 0.37 0.4245 0.9723 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H10 compound treatment 314670.0 -60500.0 -0.41 291380.0 -30800.0 -0.22 -0.4466 -0.9595 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H11 compound treatment 461710.0 86600.0 0.59 254620.0 -67600.0 -0.49 0.0678 0.0889 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H12 compound treatment 311170.0 -64000.0 -0.43 434240.0 112000.0 0.81 0.268 0.2916 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H13 compound treatment 328870.0 -46300.0 -0.31 259590.0 -62600.0 -0.45 -0.5414 -0.9835 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H14 compound treatment 370300.0 -4820.0 -0.03 378840.0 56600.0 0.41 0.2669 0.6489 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H15 compound treatment 443050.0 67900.0 0.46 357840.0 35600.0 0.26 0.507 0.9629 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H16 compound treatment 321200.0 -53900.0 -0.36 236100.0 -86100.0 -0.62 -0.6983 -0.9673 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H17 compound treatment 471920.0 96800.0 0.65 347200.0 25000.0 0.18 0.5905 0.8701 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H18 compound treatment 355890.0 -19200.0 -0.13 245600.0 -76600.0 -0.55 -0.484 -0.8498 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H19 mock treatment 452670.0 77500.0 0.52 333600.0 11400.0 0.08 0.4289 0.8086 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H20 mock treatment 446910.0 71800.0 0.49 347330.0 25100.0 0.18 0.4716 0.9104 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H21 compound treatment 303400.0 -71700.0 -0.48 288880.0 -33300.0 -0.24 -0.5132 -0.9481 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H22 compound treatment 15040.0 -360000.0 -2.43 16480.0 -306000.0 -2.21 -3.2853 -0.9989 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H23 compound treatment 20350.0 -355000.0 -2.4 17210.0 -305000.0 -2.21 -3.2562 -0.9992 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 H24 compound treatment 324900.0 -50200.0 -0.34 225230.0 -97000.0 -0.7 -0.7363 -0.9444 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I01 compound treatment 471580.0 96500.0 0.65 241250.0 -80900.0 -0.59 0.0465 0.0531 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I02 compound treatment 358620.0 -16500.0 -0.11 310820.0 -11400.0 -0.08 -0.1371 -0.9889 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I03 compound treatment 383630.0 8510.0 0.06 333500.0 11300.0 0.08 0.0985 0.9851 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I04 compound treatment 471390.0 96300.0 0.65 345460.0 23300.0 0.17 0.579 0.8618 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I05 mock treatment 376690.0 1570.0 0.01 229950.0 -92200.0 -0.67 -0.4647 -0.6958 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I06 mock treatment 344770.0 -30400.0 -0.21 244320.0 -77900.0 -0.56 -0.5436 -0.9062 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I07 compound treatment 340810.0 -34300.0 -0.23 178350.0 -144000.0 -1.04 -0.9002 -0.8439 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I08 compound treatment 281350.0 -93800.0 -0.63 224010.0 -98200.0 -0.71 -0.9506 -0.9984 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I09 compound treatment 382240.0 7120.0 0.05 319040.0 -3150.0 -0.02 0.0179 0.3354 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I10 compound treatment 318560.0 -56600.0 -0.38 264510.0 -57700.0 -0.42 -0.5655 -0.999 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I11 compound treatment 358770.0 -16400.0 -0.11 235580.0 -86600.0 -0.63 -0.5215 -0.8191 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I12 compound treatment 327520.0 -47600.0 -0.32 200970.0 -121000.0 -0.88 -0.848 -0.9073 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I13 compound treatment 381070.0 5950.0 0.04 272800.0 -49400.0 -0.36 -0.2244 -0.6237 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I14 compound treatment 415840.0 40700.0 0.28 385520.0 63300.0 0.46 0.5187 0.9702 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I15 compound treatment 276610.0 -98500.0 -0.67 271890.0 -50300.0 -0.36 -0.7282 -0.9597 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I16 compound treatment 327770.0 -47400.0 -0.32 266450.0 -55700.0 -0.4 -0.5116 -0.9934 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I17 compound treatment 344420.0 -30700.0 -0.21 232550.0 -89600.0 -0.65 -0.6056 -0.8888 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I18 compound treatment 330960.0 -44200.0 -0.3 332540.0 10300.0 0.07 -0.158 -0.5137 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I19 compound treatment 409550.0 34400.0 0.23 388700.0 66500.0 0.48 0.5049 0.9443 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I20 compound treatment 435840.0 60700.0 0.41 338800.0 16600.0 0.12 0.3751 0.8774 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I21 mock treatment 381280.0 6160.0 0.04 302880.0 -19300.0 -0.14 -0.0695 -0.4761 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I22 mock treatment 456840.0 81700.0 0.55 333350.0 11200.0 0.08 0.4475 0.802 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I23 compound treatment 307970.0 -67200.0 -0.45 216290.0 -106000.0 -0.77 -0.8629 -0.9687 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 I24 compound treatment 429080.0 54000.0 0.36 228900.0 -93300.0 -0.68 -0.2198 -0.2863 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J01 compound treatment 328290.0 -46800.0 -0.32 299680.0 -22500.0 -0.16 -0.339 -0.9524 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J02 compound treatment 286760.0 -88400.0 -0.6 220700.0 -101000.0 -0.73 -0.9417 -0.9947 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J03 compound treatment 239200.0 -136000.0 -0.92 206130.0 -116000.0 -0.84 -1.2435 -0.999 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J04 compound treatment 306990.0 -68100.0 -0.46 326340.0 4150.0 0.03 -0.3043 -0.6596 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J05 mock treatment 282970.0 -92200.0 -0.62 314900.0 -7290.0 -0.05 -0.4776 -0.7643 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J06 mock treatment 264720.0 -110000.0 -0.75 339750.0 17600.0 0.13 -0.4376 -0.5783 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J07 compound treatment 338210.0 -36900.0 -0.25 350890.0 28700.0 0.21 -0.0295 -0.0908 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J08 compound treatment 182370.0 -193000.0 -1.3 179310.0 -143000.0 -1.03 -1.6523 -0.9935 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J09 compound treatment 320820.0 -54300.0 -0.37 296110.0 -26100.0 -0.19 -0.393 -0.9523 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J10 compound treatment 314570.0 -60600.0 -0.41 264680.0 -57500.0 -0.42 -0.5837 -1.0 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J11 compound treatment 419390.0 44300.0 0.3 403360.0 81200.0 0.59 0.627 0.9509 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J12 compound treatment 239280.0 -136000.0 -0.92 308340.0 -13900.0 -0.1 -0.72 -0.7797 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J13 compound treatment 384010.0 8890.0 0.06 193490.0 -129000.0 -0.93 -0.6163 -0.6602 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J14 compound treatment 334100.0 -41000.0 -0.28 300160.0 -22000.0 -0.16 -0.3088 -0.9656 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J15 compound treatment 352870.0 -22300.0 -0.15 385170.0 63000.0 0.46 0.216 0.45 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J16 compound treatment 296000.0 -79100.0 -0.53 257380.0 -64800.0 -0.47 -0.7098 -0.9979 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J17 compound treatment 384550.0 9430.0 0.06 327360.0 5170.0 0.04 0.0715 0.9678 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J18 compound treatment 296430.0 -78700.0 -0.53 302160.0 -20000.0 -0.15 -0.4785 -0.8683 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J19 compound treatment 327650.0 -47500.0 -0.32 290600.0 -31600.0 -0.23 -0.3885 -0.9863 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J20 compound treatment 355540.0 -19600.0 -0.13 283450.0 -38700.0 -0.28 -0.2919 -0.9412 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J21 mock treatment 416870.0 41700.0 0.28 305470.0 -16700.0 -0.12 0.1138 0.3709 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J22 mock treatment 370760.0 -4360.0 -0.03 263840.0 -58400.0 -0.42 -0.3195 -0.7546 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J23 compound treatment 377680.0 2560.0 0.02 268870.0 -53300.0 -0.39 -0.2607 -0.6748 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 J24 compound treatment 348500.0 -26600.0 -0.18 279160.0 -43000.0 -0.31 -0.3475 -0.9659 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K01 compound treatment 402360.0 27200.0 0.18 433440.0 111000.0 0.81 0.6996 0.8469 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K02 compound treatment 477510.0 102000.0 0.69 325360.0 3170.0 0.02 0.5054 0.7301 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K03 compound treatment 269200.0 -106000.0 -0.72 258980.0 -63200.0 -0.46 -0.8297 -0.9766 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K04 compound treatment 400450.0 25300.0 0.17 373280.0 51100.0 0.37 0.3825 0.9387 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K05 compound treatment 399840.0 24700.0 0.17 258720.0 -63500.0 -0.46 -0.2068 -0.423 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K06 compound treatment 291360.0 -83800.0 -0.57 195270.0 -127000.0 -0.92 -1.0499 -0.9729 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K07 mock treatment 427910.0 52800.0 0.36 443960.0 122000.0 0.88 0.8755 0.9207 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K08 mock treatment 465540.0 90400.0 0.61 397290.0 75100.0 0.54 0.8164 0.9983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K09 compound treatment 320860.0 -54300.0 -0.37 228680.0 -93500.0 -0.68 -0.7379 -0.9585 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K10 compound treatment 371080.0 -4040.0 -0.03 341310.0 19100.0 0.14 0.0785 0.5568 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K11 compound treatment 249840.0 -125000.0 -0.85 256130.0 -66100.0 -0.48 -0.9367 -0.9635 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K12 compound treatment 401940.0 26800.0 0.18 327930.0 5740.0 0.04 0.1575 0.8472 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K13 compound treatment 406620.0 31500.0 0.21 330830.0 8640.0 0.06 0.1947 0.8777 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K14 compound treatment 413680.0 38600.0 0.26 417310.0 95100.0 0.69 0.6711 0.9116 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K15 mock treatment 421690.0 46600.0 0.31 447520.0 125000.0 0.91 0.864 0.8998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K16 mock treatment 491300.0 116000.0 0.78 387960.0 65800.0 0.48 0.8917 0.9713 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K17 compound treatment 398210.0 23100.0 0.16 286410.0 -35800.0 -0.26 -0.0729 -0.241 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K18 compound treatment 368600.0 -6520.0 -0.04 344570.0 22400.0 0.16 0.0834 0.4966 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K19 compound treatment 419090.0 44000.0 0.3 426170.0 104000.0 0.75 0.7423 0.9173 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K20 compound treatment 484170.0 109000.0 0.74 413040.0 90800.0 0.66 0.986 0.9984 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K21 compound treatment 314680.0 -60400.0 -0.41 308870.0 -13300.0 -0.1 -0.357 -0.8507 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K22 compound treatment 428660.0 53500.0 0.36 297140.0 -25100.0 -0.18 0.1275 0.3152 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K23 mock treatment 374330.0 -793.0 -0.01 377410.0 55200.0 0.4 0.2788 0.6976 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 K24 mock treatment 401810.0 26700.0 0.18 351070.0 28900.0 0.21 0.2753 0.9973 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L01 compound treatment 360920.0 -14200.0 -0.1 287840.0 -34400.0 -0.25 -0.2437 -0.9143 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L02 compound treatment 466100.0 91000.0 0.61 194690.0 -128000.0 -0.92 -0.218 -0.1966 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L03 compound treatment 381670.0 6550.0 0.04 295210.0 -27000.0 -0.2 -0.1068 -0.5335 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L04 compound treatment 88020.0 -287000.0 -1.94 94910.0 -227000.0 -1.65 -2.5351 -0.9966 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L05 compound treatment 194620.0 -181000.0 -1.22 202320.0 -120000.0 -0.87 -1.476 -0.9861 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L06 compound treatment 454320.0 79200.0 0.54 346810.0 24600.0 0.18 0.5044 0.8943 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L07 mock treatment 249120.0 -126000.0 -0.85 242630.0 -79600.0 -0.58 -1.0093 -0.9819 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L08 mock treatment 369230.0 -5890.0 -0.04 401210.0 79000.0 0.57 0.3763 0.6563 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L09 compound treatment 394800.0 19700.0 0.13 354370.0 32200.0 0.23 0.2587 0.9646 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L10 compound treatment 166990.0 -208000.0 -1.41 167920.0 -154000.0 -1.12 -1.7841 -0.9935 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L11 compound treatment 241480.0 -134000.0 -0.9 326610.0 4420.0 0.03 -0.6159 -0.6817 1006359 PK04_181227 Cc1cccc[n+]1C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L12 compound treatment 158170.0 -217000.0 -1.47 193450.0 -129000.0 -0.93 -1.6956 -0.9761 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L13 compound treatment 296230.0 -78900.0 -0.53 427420.0 105000.0 0.76 0.1617 0.1739 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L14 compound treatment 410830.0 35700.0 0.24 322690.0 495.0 0.0 0.1731 0.7175 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L15 mock treatment 399580.0 24500.0 0.17 300360.0 -21800.0 -0.16 0.0051 0.0222 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L16 mock treatment 391720.0 16600.0 0.11 311050.0 -11100.0 -0.08 0.0222 0.1611 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L17 compound treatment 470620.0 95500.0 0.65 275490.0 -46700.0 -0.34 0.2172 0.2982 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L18 compound treatment 319870.0 -55300.0 -0.37 374520.0 52300.0 0.38 0.0038 0.0072 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L19 compound treatment 355740.0 -19400.0 -0.13 241610.0 -80600.0 -0.58 -0.5051 -0.8448 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L20 compound treatment 190400.0 -185000.0 -1.25 177670.0 -145000.0 -1.05 -1.6223 -0.9961 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L21 compound treatment 407280.0 32200.0 0.22 336290.0 14100.0 0.1 0.2258 0.9406 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L22 compound treatment 101490.0 -274000.0 -1.85 95840.0 -226000.0 -1.64 -2.466 -0.9982 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L23 mock treatment 343370.0 -31800.0 -0.21 410000.0 87800.0 0.64 0.2977 0.4438 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 L24 mock treatment 424340.0 49200.0 0.33 318080.0 -4110.0 -0.03 0.2141 0.6412 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M01 compound treatment 412640.0 37500.0 0.25 255460.0 -66700.0 -0.48 -0.1623 -0.2976 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M02 compound treatment 270560.0 -105000.0 -0.71 135700.0 -186000.0 -1.35 -1.4542 -0.9544 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M03 compound treatment 304250.0 -70900.0 -0.48 205310.0 -117000.0 -0.85 -0.9369 -0.9637 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M04 compound treatment 17400.0 -358000.0 -2.42 20550.0 -302000.0 -2.18 -3.2532 -0.9987 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M05 compound treatment 178560.0 -197000.0 -1.33 218080.0 -104000.0 -0.75 -1.4721 -0.964 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M06 compound treatment 272320.0 -103000.0 -0.69 295410.0 -26800.0 -0.19 -0.6283 -0.8712 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M07 compound treatment 243860.0 -131000.0 -0.89 378310.0 56100.0 0.41 -0.3399 -0.3484 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M08 compound treatment 377870.0 2750.0 0.02 203440.0 -119000.0 -0.86 -0.5947 -0.6917 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M09 mock treatment 377570.0 2450.0 0.02 371850.0 49700.0 0.36 0.2659 0.7388 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M10 mock treatment 332480.0 -42600.0 -0.29 343680.0 21500.0 0.16 -0.0938 -0.2864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M11 compound treatment 247770.0 -127000.0 -0.86 222400.0 -99800.0 -0.72 -1.1193 -0.9962 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M12 compound treatment 484320.0 109000.0 0.74 391200.0 69000.0 0.5 0.8749 0.982 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M13 mock treatment 373680.0 -1440.0 -0.01 294950.0 -27200.0 -0.2 -0.1464 -0.7412 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M14 mock treatment 422720.0 47600.0 0.32 265970.0 -56200.0 -0.41 -0.0604 -0.1164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M15 compound treatment 306910.0 -68200.0 -0.46 228130.0 -94100.0 -0.68 -0.8074 -0.9819 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M16 compound treatment 35300.0 -340000.0 -2.3 33400.0 -289000.0 -2.09 -3.1019 -0.9989 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M17 compound treatment 312580.0 -62500.0 -0.42 240160.0 -82000.0 -0.59 -0.7187 -0.9861 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M18 compound treatment 336830.0 -38300.0 -0.26 248970.0 -73200.0 -0.53 -0.5578 -0.9456 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M19 compound treatment 303330.0 -71800.0 -0.49 214400.0 -108000.0 -0.78 -0.8948 -0.9738 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M20 compound treatment 281280.0 -93800.0 -0.63 234880.0 -87300.0 -0.63 -0.8953 -1.0 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M21 compound treatment 244800.0 -130000.0 -0.88 297320.0 -24900.0 -0.18 -0.75 -0.8344 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M22 compound treatment 339220.0 -35900.0 -0.24 307450.0 -14700.0 -0.11 -0.247 -0.932 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M23 compound treatment 221280.0 -154000.0 -1.04 228120.0 -94100.0 -0.68 -1.2166 -0.979 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 M24 compound treatment 465280.0 90200.0 0.61 345060.0 22900.0 0.17 0.5478 0.8678 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N01 compound treatment 355370.0 -19800.0 -0.13 228800.0 -93400.0 -0.68 -0.5724 -0.8307 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N02 compound treatment 293320.0 -81800.0 -0.55 397630.0 75400.0 0.55 -0.0047 -0.0061 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N03 compound treatment 364220.0 -10900.0 -0.07 276110.0 -46100.0 -0.33 -0.288 -0.843 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N04 compound treatment 359910.0 -15200.0 -0.1 240720.0 -81500.0 -0.59 -0.4897 -0.818 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N05 compound treatment 242410.0 -133000.0 -0.9 246490.0 -75700.0 -0.55 -1.0216 -0.9721 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N06 compound treatment 418180.0 43100.0 0.29 181720.0 -140000.0 -1.02 -0.5133 -0.4853 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N07 compound treatment 182430.0 -193000.0 -1.3 217710.0 -104000.0 -0.76 -1.4555 -0.9666 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N08 compound treatment 458660.0 83500.0 0.56 243100.0 -79100.0 -0.57 -0.0057 -0.0071 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N09 mock treatment 427900.0 52800.0 0.36 336600.0 14400.0 0.1 0.3259 0.8771 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N10 mock treatment 283720.0 -91400.0 -0.62 245920.0 -76300.0 -0.55 -0.8271 -0.9984 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N11 compound treatment 380100.0 4980.0 0.03 219920.0 -102000.0 -0.74 -0.4997 -0.6743 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N12 compound treatment 348200.0 -26900.0 -0.18 333440.0 11200.0 0.08 -0.0711 -0.3566 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N13 mock treatment 435550.0 60400.0 0.41 339480.0 17300.0 0.13 0.3772 0.8833 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N14 mock treatment 425520.0 50400.0 0.34 389210.0 67000.0 0.49 0.5838 0.985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N15 compound treatment 512680.0 138000.0 0.93 305060.0 -17100.0 -0.12 0.5695 0.6074 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N16 compound treatment 397850.0 22700.0 0.15 297920.0 -24300.0 -0.18 -0.0157 -0.0672 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N17 compound treatment 316200.0 -58900.0 -0.4 265950.0 -56200.0 -0.41 -0.5694 -0.9999 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N18 compound treatment 362640.0 -12500.0 -0.08 333230.0 11000.0 0.08 -0.0032 -0.0272 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N19 compound treatment 360960.0 -14200.0 -0.1 294400.0 -27800.0 -0.2 -0.2099 -0.9423 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N20 compound treatment 197920.0 -177000.0 -1.2 211050.0 -111000.0 -0.8 -1.4156 -0.9813 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N21 compound treatment 242780.0 -132000.0 -0.89 190270.0 -132000.0 -0.95 -1.3076 -0.9995 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N22 compound treatment 384680.0 9560.0 0.06 301600.0 -20600.0 -0.15 -0.0598 -0.3678 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N23 compound treatment 274170.0 -101000.0 -0.68 415290.0 93100.0 0.67 -0.0058 -0.0061 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 N24 compound treatment 459040.0 83900.0 0.57 290920.0 -31300.0 -0.23 0.2409 0.3945 1004341 PK04_181276 c1ccc2cnccc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O01 compound treatment 341040.0 -34100.0 -0.23 411000.0 88800.0 0.64 0.2917 0.4272 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O02 compound treatment 207860.0 -167000.0 -1.13 205630.0 -117000.0 -0.84 -1.3958 -0.9896 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O03 compound treatment 257450.0 -118000.0 -0.8 151410.0 -171000.0 -1.24 -1.4364 -0.9772 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O04 compound treatment 123700.0 -251000.0 -1.7 97240.0 -225000.0 -1.63 -2.3527 -0.9998 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O05 compound treatment 307910.0 -67200.0 -0.45 262820.0 -59400.0 -0.43 -0.6251 -0.9996 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O06 compound treatment 158760.0 -216000.0 -1.46 152160.0 -170000.0 -1.23 -1.9041 -0.9963 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O07 compound treatment 164760.0 -210000.0 -1.42 131270.0 -191000.0 -1.38 -1.9824 -0.9999 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O08 compound treatment 74640.0 -300000.0 -2.03 83950.0 -238000.0 -1.72 -2.6552 -0.9967 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O09 compound treatment 293600.0 -81500.0 -0.55 235970.0 -86200.0 -0.62 -0.8309 -0.9981 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O10 compound treatment 313970.0 -61200.0 -0.41 313540.0 -8650.0 -0.06 -0.3365 -0.8051 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O11 mock treatment 253920.0 -121000.0 -0.82 321640.0 -555.0 0.0 -0.5819 -0.7106 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O12 mock treatment 316130.0 -59000.0 -0.4 365120.0 42900.0 0.31 -0.0621 -0.1229 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O13 compound treatment 284060.0 -91100.0 -0.62 344570.0 22400.0 0.16 -0.3205 -0.5038 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O14 compound treatment 363520.0 -11600.0 -0.08 363290.0 41100.0 0.3 0.1549 0.5036 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O15 compound treatment 298440.0 -76700.0 -0.52 252970.0 -69200.0 -0.5 -0.7207 -0.9999 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O16 compound treatment 386720.0 11600.0 0.08 393170.0 71000.0 0.51 0.4187 0.8056 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O17 compound treatment 250880.0 -124000.0 -0.84 309500.0 -12700.0 -0.09 -0.6586 -0.7799 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O18 compound treatment 288490.0 -86600.0 -0.59 295520.0 -26700.0 -0.19 -0.5505 -0.893 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O19 compound treatment 295380.0 -79700.0 -0.54 295160.0 -27000.0 -0.2 -0.5194 -0.906 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O20 compound treatment 438400.0 63300.0 0.43 280260.0 -41900.0 -0.3 0.0877 0.1672 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O21 compound treatment 216700.0 -158000.0 -1.07 244320.0 -77900.0 -0.56 -1.1555 -0.9551 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O22 compound treatment 286490.0 -88600.0 -0.6 316800.0 -5390.0 -0.04 -0.4511 -0.7516 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O23 compound treatment 229670.0 -145000.0 -0.98 399530.0 77300.0 0.56 -0.2991 -0.2644 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 O24 compound treatment 364050.0 -11100.0 -0.07 276330.0 -45900.0 -0.33 -0.2877 -0.8453 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P01 compound treatment 166450.0 -209000.0 -1.41 177010.0 -145000.0 -1.05 -1.7402 -0.9895 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P02 compound treatment 179490.0 -196000.0 -1.32 258880.0 -63300.0 -0.46 -1.2588 -0.8997 1015751 PK04_181300 Cc1ccncc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P03 compound treatment 242110.0 -133000.0 -0.9 210210.0 -112000.0 -0.81 -1.2087 -0.9987 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P04 compound treatment 351650.0 -23500.0 -0.16 299950.0 -22200.0 -0.16 -0.226 -1.0 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P05 compound treatment 168320.0 -207000.0 -1.4 135040.0 -187000.0 -1.35 -1.9461 -0.9999 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P06 compound treatment 182630.0 -192000.0 -1.3 263620.0 -58600.0 -0.42 -1.2195 -0.8915 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P07 compound treatment 235970.0 -139000.0 -0.94 102560.0 -220000.0 -1.59 -1.7891 -0.9686 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P08 compound treatment 203650.0 -171000.0 -1.16 270690.0 -51500.0 -0.37 -1.0829 -0.8897 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P09 compound treatment 204830.0 -170000.0 -1.15 200660.0 -122000.0 -0.88 -1.4357 -0.9912 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P10 compound treatment 230130.0 -145000.0 -0.98 251240.0 -71000.0 -0.51 -1.0559 -0.9546 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P11 mock treatment 325450.0 -49700.0 -0.34 213020.0 -109000.0 -0.79 -0.7962 -0.9273 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P12 mock treatment 228370.0 -147000.0 -0.99 278580.0 -43600.0 -0.32 -0.9244 -0.8883 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P13 compound treatment 224040.0 -151000.0 -1.02 236480.0 -85700.0 -0.62 -1.1606 -0.9715 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P14 compound treatment 242100.0 -133000.0 -0.9 218940.0 -103000.0 -0.75 -1.1641 -0.9958 1009497 PK04_181310 Cc1cc[n+](C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P15 compound treatment 186010.0 -189000.0 -1.28 239730.0 -82500.0 -0.6 -1.3257 -0.9399 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P16 compound treatment 233020.0 -142000.0 -0.96 225760.0 -96400.0 -0.7 -1.1726 -0.9877 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P17 compound treatment 242940.0 -132000.0 -0.89 201980.0 -120000.0 -0.87 -1.2469 -0.9999 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P18 compound treatment 236680.0 -138000.0 -0.94 226240.0 -96000.0 -0.69 -1.1526 -0.9893 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P19 compound treatment 249540.0 -126000.0 -0.85 246340.0 -75900.0 -0.55 -0.9883 -0.9778 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P20 compound treatment 261720.0 -113000.0 -0.77 211770.0 -110000.0 -0.8 -1.107 -0.9998 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P21 compound treatment 243260.0 -132000.0 -0.89 242950.0 -79200.0 -0.57 -1.0356 -0.9773 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P22 compound treatment 332330.0 -42800.0 -0.29 210570.0 -112000.0 -0.81 -0.7758 -0.904 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P23 compound treatment 227810.0 -147000.0 -1.0 207560.0 -115000.0 -0.83 -1.2906 -0.9959 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2181 P24 compound treatment 250080.0 -125000.0 -0.84 182880.0 -139000.0 -1.01 -1.3105 -0.9961 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A01 compound treatment 265440.0 -127000.0 -0.86 147200.0 -282000.0 -2.04 -2.0488 -0.9263 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A02 compound treatment 457000.0 64400.0 0.44 312700.0 -116000.0 -0.84 -0.2864 -0.3027 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A03 compound treatment 513860.0 121000.0 0.82 312750.0 -116000.0 -0.84 -0.0145 -0.0123 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A04 compound treatment 325480.0 -67100.0 -0.45 371740.0 -57000.0 -0.41 -0.6126 -0.9989 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A05 compound treatment 292850.0 -99800.0 -0.67 545170.0 116000.0 0.84 0.1193 0.1105 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A06 compound treatment 235960.0 -157000.0 -1.06 182420.0 -246000.0 -1.78 -2.0093 -0.969 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A07 compound treatment 515540.0 123000.0 0.83 499090.0 70300.0 0.51 0.9474 0.9724 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A08 compound treatment 269560.0 -123000.0 -0.83 239800.0 -189000.0 -1.37 -1.5551 -0.9715 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A09 compound treatment 451580.0 59000.0 0.4 271840.0 -157000.0 -1.14 -0.5214 -0.4332 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A10 compound treatment 324830.0 -67800.0 -0.46 434410.0 5660.0 0.04 -0.2949 -0.6413 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A11 compound treatment 306650.0 -86000.0 -0.58 271200.0 -158000.0 -1.14 -1.2172 -0.951 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A12 compound treatment 256370.0 -136000.0 -0.92 317440.0 -111000.0 -0.81 -1.2207 -0.9978 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A13 mock treatment 439200.0 46600.0 0.31 244320.0 -184000.0 -1.34 -0.7214 -0.526 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A14 mock treatment 217130.0 -175000.0 -1.19 460480.0 31700.0 0.23 -0.676 -0.5597 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A15 compound treatment 328380.0 -64200.0 -0.43 422180.0 -6570.0 -0.05 -0.3405 -0.7799 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A16 compound treatment 359690.0 -32900.0 -0.22 348770.0 -80000.0 -0.58 -0.5667 -0.9137 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A17 compound treatment 404000.0 11400.0 0.08 469970.0 41200.0 0.3 0.2654 0.8613 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A18 compound treatment 259580.0 -133000.0 -0.9 338460.0 -90300.0 -0.65 -1.0978 -0.9877 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A19 compound treatment 411240.0 18600.0 0.13 305570.0 -123000.0 -0.89 -0.5415 -0.6013 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A20 compound treatment 229990.0 -163000.0 -1.1 328960.0 -99800.0 -0.72 -1.2878 -0.9793 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A21 compound treatment 290410.0 -102000.0 -0.69 427780.0 -969.0 -0.01 -0.4933 -0.7143 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A22 compound treatment 301500.0 -91100.0 -0.62 268120.0 -161000.0 -1.16 -1.2575 -0.9558 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A23 compound treatment 344960.0 -47700.0 -0.32 385480.0 -43300.0 -0.31 -0.4492 -0.9999 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 A24 compound treatment 293280.0 -99300.0 -0.67 295590.0 -133000.0 -0.96 -1.1562 -0.9843 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B01 compound treatment 380520.0 -12100.0 -0.08 579290.0 151000.0 1.09 0.7128 0.6523 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B02 compound treatment 215360.0 -177000.0 -1.2 372320.0 -56400.0 -0.41 -1.1357 -0.8975 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B03 compound treatment 539910.0 147000.0 1.0 355040.0 -73700.0 -0.53 0.3265 0.2891 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B04 compound treatment 240530.0 -152000.0 -1.03 362880.0 -65900.0 -0.48 -1.0638 -0.939 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B05 compound treatment 348850.0 -43800.0 -0.3 532350.0 104000.0 0.75 0.3212 0.3985 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B06 compound treatment 227780.0 -165000.0 -1.11 228080.0 -201000.0 -1.45 -1.8147 -0.9914 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B07 compound treatment 331470.0 -61100.0 -0.41 533400.0 105000.0 0.76 0.2436 0.2823 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B08 compound treatment 466240.0 73600.0 0.5 315520.0 -113000.0 -0.82 -0.2278 -0.2376 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B09 compound treatment 317230.0 -75400.0 -0.51 437310.0 8560.0 0.06 -0.3163 -0.6165 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B10 compound treatment 517150.0 125000.0 0.84 466840.0 38100.0 0.28 0.79 0.8921 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B11 compound treatment 266750.0 -126000.0 -0.85 367330.0 -61400.0 -0.44 -0.9157 -0.9542 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B12 compound treatment 338790.0 -53800.0 -0.36 370910.0 -57800.0 -0.42 -0.5532 -0.9975 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B13 mock treatment 388030.0 -4580.0 -0.03 472520.0 43800.0 0.32 0.2022 0.635 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B14 mock treatment 322240.0 -70400.0 -0.48 345870.0 -82900.0 -0.6 -0.7605 -0.9934 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B15 compound treatment 392120.0 -492.0 0.0 432710.0 3960.0 0.03 0.0179 0.621 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B16 compound treatment 349470.0 -43100.0 -0.29 428000.0 -749.0 -0.01 -0.21 -0.7201 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B17 compound treatment 399420.0 6810.0 0.05 342400.0 -86300.0 -0.63 -0.4095 -0.6533 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B18 compound treatment 237160.0 -155000.0 -1.05 406850.0 -21900.0 -0.16 -0.8548 -0.8047 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B19 compound treatment 407600.0 15000.0 0.1 461570.0 32800.0 0.24 0.2396 0.9277 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B20 compound treatment 285820.0 -107000.0 -0.72 391140.0 -37600.0 -0.27 -0.7027 -0.9112 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B21 compound treatment 298560.0 -94100.0 -0.64 383310.0 -45400.0 -0.33 -0.6819 -0.953 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B22 compound treatment 260520.0 -132000.0 -0.89 390900.0 -37800.0 -0.27 -0.8248 -0.8835 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B23 compound treatment 269440.0 -123000.0 -0.83 354440.0 -74300.0 -0.54 -0.9689 -0.9777 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 B24 compound treatment 305360.0 -87300.0 -0.59 247690.0 -181000.0 -1.31 -1.3437 -0.9349 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C01 compound treatment 254820.0 -138000.0 -0.93 349220.0 -79500.0 -0.58 -1.0654 -0.9733 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C02 compound treatment 492730.0 100000.0 0.68 441850.0 13100.0 0.09 0.5454 0.7984 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C03 compound treatment 506020.0 113000.0 0.77 495050.0 66300.0 0.48 0.8812 0.9746 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C04 compound treatment 233760.0 -159000.0 -1.07 360900.0 -67800.0 -0.49 -1.1063 -0.9372 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C05 compound treatment 244490.0 -148000.0 -1.0 434840.0 6090.0 0.04 -0.6765 -0.6753 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C06 compound treatment 441760.0 49100.0 0.33 260770.0 -168000.0 -1.22 -0.625 -0.4958 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C07 compound treatment 363490.0 -29100.0 -0.2 506620.0 77900.0 0.56 0.2595 0.4346 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C08 compound treatment 294730.0 -97900.0 -0.66 487550.0 58800.0 0.43 -0.1667 -0.2119 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C09 compound treatment 412530.0 19900.0 0.13 326200.0 -103000.0 -0.74 -0.4298 -0.5696 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C10 compound treatment 303880.0 -88700.0 -0.6 357380.0 -71400.0 -0.52 -0.7893 -0.9973 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C11 mock treatment 334970.0 -57600.0 -0.39 468210.0 39500.0 0.29 -0.0734 -0.152 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C12 mock treatment 502770.0 110000.0 0.74 511790.0 83000.0 0.6 0.9514 0.9944 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C13 compound treatment 217520.0 -175000.0 -1.18 292920.0 -136000.0 -0.98 -1.5318 -0.9958 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C14 compound treatment 366080.0 -26500.0 -0.18 371840.0 -56900.0 -0.41 -0.4181 -0.9305 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C15 mock treatment 431330.0 38700.0 0.26 472230.0 43500.0 0.31 0.4076 0.9958 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C16 mock treatment 372320.0 -20300.0 -0.14 286480.0 -142000.0 -1.03 -0.8252 -0.7942 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C17 compound treatment 364510.0 -28100.0 -0.19 274880.0 -154000.0 -1.11 -0.9219 -0.8159 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C18 compound treatment 302820.0 -89800.0 -0.61 433320.0 4570.0 0.03 -0.4056 -0.6675 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C19 compound treatment 15200.0 -377000.0 -2.55 19470.0 -409000.0 -2.96 -3.8982 -0.9972 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C20 compound treatment 262240.0 -130000.0 -0.88 561760.0 133000.0 0.96 0.058 0.0444 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C21 compound treatment 253770.0 -139000.0 -0.94 412800.0 -15900.0 -0.12 -0.745 -0.7882 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C22 compound treatment 281770.0 -111000.0 -0.75 450810.0 22100.0 0.16 -0.4167 -0.5441 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C23 compound treatment 268930.0 -124000.0 -0.84 337460.0 -91300.0 -0.66 -1.0582 -0.9932 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 C24 compound treatment 289920.0 -103000.0 -0.69 324240.0 -105000.0 -0.76 -1.0256 -0.9991 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D01 compound treatment 245990.0 -147000.0 -0.99 328390.0 -100000.0 -0.73 -1.2142 -0.9884 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D02 compound treatment 62020.0 -331000.0 -2.23 59840.0 -369000.0 -2.67 -3.4678 -0.9961 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D03 compound treatment 465410.0 72800.0 0.49 298520.0 -130000.0 -0.94 -0.3188 -0.2998 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D04 compound treatment 268690.0 -124000.0 -0.84 280810.0 -148000.0 -1.07 -1.3493 -0.9926 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D05 compound treatment 510950.0 118000.0 0.8 229790.0 -199000.0 -1.44 -0.453 -0.275 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D06 compound treatment 192100.0 -201000.0 -1.35 272160.0 -157000.0 -1.13 -1.7595 -0.9961 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D07 compound treatment 210150.0 -182000.0 -1.23 320070.0 -109000.0 -0.79 -1.4281 -0.9765 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D08 compound treatment 447840.0 55200.0 0.37 453780.0 25000.0 0.18 0.392 0.9449 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D09 compound treatment 466780.0 74200.0 0.5 466200.0 37500.0 0.27 0.5461 0.9584 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D10 compound treatment 507420.0 115000.0 0.78 489330.0 60600.0 0.44 0.8586 0.9635 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D11 mock treatment 523370.0 131000.0 0.88 373000.0 -55700.0 -0.4 0.3394 0.3494 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D12 mock treatment 378290.0 -14300.0 -0.1 493480.0 64700.0 0.47 0.2629 0.5495 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D13 compound treatment 547130.0 155000.0 1.04 384370.0 -44400.0 -0.32 0.5111 0.4679 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D14 compound treatment 284290.0 -108000.0 -0.73 220540.0 -208000.0 -1.51 -1.5833 -0.945 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D15 mock treatment 279240.0 -113000.0 -0.77 403150.0 -25600.0 -0.19 -0.6727 -0.8535 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D16 mock treatment 341010.0 -51600.0 -0.35 362120.0 -66600.0 -0.48 -0.5876 -0.9873 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D17 compound treatment 355460.0 -37200.0 -0.25 410040.0 -18700.0 -0.14 -0.2733 -0.9581 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D18 compound treatment 230420.0 -162000.0 -1.1 287040.0 -142000.0 -1.03 -1.5003 -0.9995 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D19 compound treatment 341600.0 -51000.0 -0.34 379320.0 -49400.0 -0.36 -0.4967 -0.9998 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D20 compound treatment 345390.0 -47200.0 -0.32 547810.0 119000.0 0.86 0.3838 0.4176 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D21 compound treatment 353710.0 -38900.0 -0.26 370690.0 -58100.0 -0.42 -0.4831 -0.9745 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D22 compound treatment 207430.0 -185000.0 -1.25 209970.0 -219000.0 -1.58 -2.0046 -0.9932 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D23 compound treatment 318340.0 -74300.0 -0.5 538400.0 110000.0 0.79 0.2064 0.2198 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 D24 compound treatment 333120.0 -59500.0 -0.4 430400.0 1650.0 0.01 -0.2758 -0.6858 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E01 mock treatment 295140.0 -97500.0 -0.66 534490.0 106000.0 0.77 0.0756 0.0748 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E02 mock treatment 480930.0 88300.0 0.6 377280.0 -51500.0 -0.37 0.1585 0.2253 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E03 mock treatment 312030.0 -80600.0 -0.54 321440.0 -107000.0 -0.78 -0.9343 -0.9849 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E04 compound treatment 302740.0 -89900.0 -0.61 435620.0 6870.0 0.05 -0.3942 -0.647 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E05 compound treatment 576970.0 184000.0 1.25 290350.0 -138000.0 -1.0 0.1724 0.1078 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E06 compound treatment 277890.0 -115000.0 -0.78 419230.0 -9520.0 -0.07 -0.5968 -0.7669 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E07 compound treatment 501040.0 108000.0 0.73 393810.0 -34900.0 -0.25 0.3392 0.4377 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E08 compound treatment 418630.0 26000.0 0.18 481630.0 52900.0 0.38 0.395 0.9377 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E09 mock treatment 307270.0 -85300.0 -0.58 519650.0 90900.0 0.66 0.0575 0.0658 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E10 mock treatment 499770.0 107000.0 0.72 509550.0 80800.0 0.58 0.9256 0.9944 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E11 compound treatment 535480.0 143000.0 0.97 539360.0 111000.0 0.8 1.2488 0.9957 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E12 compound treatment 232840.0 -160000.0 -1.08 253840.0 -175000.0 -1.27 -1.6587 -0.9969 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E13 compound treatment 359310.0 -33300.0 -0.23 474950.0 46200.0 0.33 0.0774 0.192 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E14 compound treatment 502010.0 109000.0 0.74 368580.0 -60200.0 -0.44 0.2147 0.2502 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E15 compound treatment 327460.0 -65200.0 -0.44 213800.0 -215000.0 -1.56 -1.4115 -0.8729 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E16 compound treatment 389370.0 -3240.0 -0.02 420440.0 -8310.0 -0.06 -0.058 -0.9064 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E17 mock treatment 307060.0 -85600.0 -0.58 534920.0 106000.0 0.77 0.1347 0.1401 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E18 mock treatment 398990.0 6380.0 0.04 318980.0 -110000.0 -0.79 -0.5314 -0.6678 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E19 compound treatment 265130.0 -127000.0 -0.86 431480.0 2730.0 0.02 -0.5951 -0.6907 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E20 compound treatment 328580.0 -64000.0 -0.43 319130.0 -110000.0 -0.79 -0.867 -0.9593 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E21 compound treatment 296350.0 -96300.0 -0.65 370950.0 -57800.0 -0.42 -0.7558 -0.9772 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E22 compound treatment 382940.0 -9670.0 -0.07 468540.0 39800.0 0.29 0.1575 0.5331 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E23 compound treatment 229210.0 -163000.0 -1.1 394940.0 -33800.0 -0.24 -0.9538 -0.8434 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 E24 compound treatment 248230.0 -144000.0 -0.98 301840.0 -127000.0 -0.92 -1.3394 -0.9995 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F01 mock treatment 294310.0 -98300.0 -0.66 349060.0 -79700.0 -0.58 -0.8776 -0.9975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F02 mock treatment 291890.0 -101000.0 -0.68 586840.0 158000.0 1.14 0.328 0.2463 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F03 compound treatment 329890.0 -62700.0 -0.42 573760.0 145000.0 1.05 0.4426 0.391 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F04 compound treatment 451440.0 58800.0 0.4 513940.0 85200.0 0.62 0.7171 0.9774 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F05 compound treatment 153610.0 -239000.0 -1.61 500910.0 72200.0 0.52 -0.7725 -0.4552 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F06 compound treatment 478320.0 85700.0 0.58 408260.0 -20500.0 -0.15 0.3046 0.5096 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F07 compound treatment 640350.0 248000.0 1.67 570940.0 142000.0 1.03 1.9115 0.9727 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F08 compound treatment 328510.0 -64100.0 -0.43 564320.0 136000.0 0.98 0.3877 0.3614 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F09 mock treatment 432750.0 40100.0 0.27 319740.0 -109000.0 -0.79 -0.3662 -0.4389 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F10 mock treatment 499890.0 107000.0 0.72 378090.0 -50700.0 -0.37 0.2532 0.3117 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F11 compound treatment 302510.0 -90100.0 -0.61 538400.0 110000.0 0.79 0.1308 0.1307 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F12 compound treatment 198920.0 -194000.0 -1.31 596010.0 167000.0 1.21 -0.0693 -0.0388 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F13 compound treatment 370670.0 -21900.0 -0.15 572110.0 143000.0 1.04 0.629 0.6 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F14 compound treatment 468910.0 76300.0 0.52 553470.0 125000.0 0.9 1.0029 0.9647 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F15 compound treatment 350350.0 -42300.0 -0.29 452800.0 24100.0 0.17 -0.0788 -0.2356 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F16 compound treatment 209760.0 -183000.0 -1.24 332840.0 -95900.0 -0.69 -1.3646 -0.9628 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F17 mock treatment 383680.0 -8930.0 -0.06 441870.0 13100.0 0.09 0.0245 0.2176 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F18 mock treatment 422420.0 29800.0 0.2 494310.0 65600.0 0.47 0.478 0.9272 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F19 compound treatment 305280.0 -87300.0 -0.59 494880.0 66100.0 0.48 -0.0787 -0.1036 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F20 compound treatment 203470.0 -189000.0 -1.28 285250.0 -143000.0 -1.04 -1.6382 -0.9947 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F21 compound treatment 241440.0 -151000.0 -1.02 320740.0 -108000.0 -0.78 -1.2751 -0.9913 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F22 compound treatment 220320.0 -172000.0 -1.16 192920.0 -236000.0 -1.71 -2.0303 -0.9826 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F23 compound treatment 364110.0 -28500.0 -0.19 320160.0 -109000.0 -0.79 -0.692 -0.8551 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 F24 compound treatment 343900.0 -48700.0 -0.33 412920.0 -15800.0 -0.11 -0.3138 -0.9003 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G01 compound treatment 511450.0 119000.0 0.8 498950.0 70200.0 0.51 0.9271 0.9756 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G02 compound treatment 503040.0 110000.0 0.75 393280.0 -35500.0 -0.26 0.346 0.4385 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G03 mock treatment 497120.0 105000.0 0.71 512440.0 83700.0 0.61 0.9277 0.9971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G04 mock treatment 604480.0 212000.0 1.43 317620.0 -111000.0 -0.8 0.4434 0.27 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G05 compound treatment 464350.0 71700.0 0.48 499330.0 70600.0 0.51 0.704 0.9997 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G06 compound treatment 284550.0 -108000.0 -0.73 489860.0 61100.0 0.44 -0.2035 -0.2384 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G07 compound treatment 480100.0 87500.0 0.59 511940.0 83200.0 0.6 0.8438 1.0 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G08 compound treatment 336820.0 -55800.0 -0.38 483090.0 54300.0 0.39 0.0116 0.0213 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G09 compound treatment 315130.0 -77500.0 -0.52 307380.0 -121000.0 -0.88 -0.9914 -0.9694 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G10 compound treatment 297350.0 -95300.0 -0.64 320170.0 -109000.0 -0.79 -1.0109 -0.9951 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G11 compound treatment 349680.0 -42900.0 -0.29 358560.0 -70200.0 -0.51 -0.5644 -0.9647 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G12 compound treatment 149350.0 -243000.0 -1.64 233680.0 -195000.0 -1.41 -2.1608 -0.9971 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G13 compound treatment 269200.0 -123000.0 -0.83 193030.0 -236000.0 -1.71 -1.7962 -0.9458 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G14 compound treatment 330840.0 -61800.0 -0.42 483040.0 54300.0 0.39 -0.0172 -0.0301 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G15 compound treatment 529780.0 137000.0 0.93 420030.0 -8720.0 -0.06 0.6107 0.6574 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G16 compound treatment 364520.0 -28100.0 -0.19 507520.0 78800.0 0.57 0.269 0.4476 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G17 compound treatment 312120.0 -80500.0 -0.54 371250.0 -57500.0 -0.42 -0.6789 -0.9913 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G18 compound treatment 328930.0 -63700.0 -0.43 543550.0 115000.0 0.83 0.2834 0.3028 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G19 mock treatment 355380.0 -37200.0 -0.25 457600.0 28900.0 0.21 -0.0302 -0.0924 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G20 mock treatment 474020.0 81400.0 0.55 311200.0 -118000.0 -0.85 -0.2127 -0.21 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G21 compound treatment 464340.0 71700.0 0.48 236820.0 -192000.0 -1.39 -0.6397 -0.4348 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G22 compound treatment 268390.0 -124000.0 -0.84 351900.0 -76800.0 -0.56 -0.9869 -0.98 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G23 compound treatment 27910.0 -365000.0 -2.46 25210.0 -404000.0 -2.92 -3.8081 -0.9964 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 G24 compound treatment 342130.0 -50500.0 -0.34 338900.0 -89800.0 -0.65 -0.7011 -0.9546 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H01 compound treatment 532000.0 139000.0 0.94 357680.0 -71100.0 -0.51 0.3022 0.2816 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H02 compound treatment 390080.0 -2530.0 -0.02 264160.0 -165000.0 -1.19 -0.8546 -0.7172 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H03 mock treatment 310840.0 -81800.0 -0.55 576480.0 148000.0 1.07 0.3655 0.3036 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H04 mock treatment 295900.0 -96700.0 -0.65 183530.0 -245000.0 -1.78 -1.7173 -0.9078 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H05 compound treatment 389700.0 -2910.0 -0.02 313600.0 -115000.0 -0.83 -0.6033 -0.7236 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H06 compound treatment 481760.0 89100.0 0.6 445120.0 16400.0 0.12 0.5097 0.8303 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H07 compound treatment 337600.0 -55000.0 -0.37 300980.0 -128000.0 -0.92 -0.9168 -0.9198 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H08 compound treatment 222810.0 -170000.0 -1.15 325490.0 -103000.0 -0.75 -1.3398 -0.9785 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H09 compound treatment 555460.0 163000.0 1.1 474750.0 46000.0 0.33 1.0135 0.8816 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H10 compound treatment 400870.0 8260.0 0.06 519960.0 91200.0 0.66 0.5063 0.7641 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H11 compound treatment 254400.0 -138000.0 -0.93 394310.0 -34400.0 -0.25 -0.8366 -0.8656 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H12 compound treatment 330890.0 -61700.0 -0.42 438400.0 9650.0 0.07 -0.2455 -0.5806 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H13 compound treatment 374400.0 -18200.0 -0.12 381060.0 -47700.0 -0.35 -0.3311 -0.9035 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H14 compound treatment 215880.0 -177000.0 -1.19 354080.0 -74700.0 -0.54 -1.2266 -0.9358 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H15 compound treatment 344330.0 -48300.0 -0.33 350460.0 -78300.0 -0.57 -0.6314 -0.9656 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H16 compound treatment 384170.0 -8440.0 -0.06 348800.0 -79900.0 -0.58 -0.4496 -0.7731 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H17 compound treatment 434280.0 41700.0 0.28 542260.0 114000.0 0.82 0.7801 0.8981 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H18 compound treatment 200050.0 -193000.0 -1.3 300330.0 -128000.0 -0.93 -1.5774 -0.9864 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H19 mock treatment 321440.0 -71200.0 -0.48 445290.0 16500.0 0.12 -0.2554 -0.5153 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H20 mock treatment 416240.0 23600.0 0.16 635420.0 207000.0 1.5 1.1708 0.7781 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H21 compound treatment 321990.0 -70600.0 -0.48 453930.0 25200.0 0.18 -0.2085 -0.4082 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H22 compound treatment 223050.0 -170000.0 -1.15 261120.0 -168000.0 -1.21 -1.6682 -0.9996 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H23 compound treatment 433880.0 41300.0 0.28 332830.0 -95900.0 -0.69 -0.2938 -0.3927 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 H24 compound treatment 253250.0 -139000.0 -0.94 243520.0 -185000.0 -1.34 -1.614 -0.985 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I01 compound treatment 494930.0 102000.0 0.69 476270.0 47500.0 0.34 0.7321 0.9481 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I02 compound treatment 283390.0 -109000.0 -0.74 320170.0 -109000.0 -0.79 -1.0776 -0.9995 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I03 compound treatment 208350.0 -184000.0 -1.25 597310.0 169000.0 1.22 -0.0176 -0.0101 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I04 compound treatment 437660.0 45000.0 0.3 301890.0 -127000.0 -0.92 -0.4341 -0.4487 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I05 mock treatment 513160.0 121000.0 0.81 303090.0 -126000.0 -0.91 -0.0673 -0.0551 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I06 mock treatment 450400.0 57800.0 0.39 431260.0 2510.0 0.02 0.289 0.7392 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I07 compound treatment 195250.0 -197000.0 -1.33 198590.0 -230000.0 -1.67 -2.1211 -0.9939 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I08 compound treatment 256930.0 -136000.0 -0.92 189680.0 -239000.0 -1.73 -1.872 -0.9559 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I09 compound treatment 273050.0 -120000.0 -0.81 252130.0 -177000.0 -1.28 -1.4753 -0.9755 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I10 compound treatment 577760.0 185000.0 1.25 461760.0 33000.0 0.24 1.0536 0.8272 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I11 compound treatment 433190.0 40600.0 0.27 501290.0 72500.0 0.53 0.5652 0.9541 BCB03_000168 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I12 compound treatment 276640.0 -116000.0 -0.78 303270.0 -125000.0 -0.91 -1.1964 -0.9973 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I13 compound treatment 9130.0 -383000.0 -2.59 9320.0 -419000.0 -3.04 -3.9791 -0.9969 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I14 compound treatment 395040.0 2430.0 0.02 393890.0 -34900.0 -0.25 -0.1668 -0.6597 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I15 compound treatment 422140.0 29500.0 0.2 429340.0 591.0 0.0 0.1441 0.7221 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I16 compound treatment 304380.0 -88200.0 -0.6 262330.0 -166000.0 -1.2 -1.2734 -0.9474 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I17 compound treatment 464260.0 71600.0 0.48 486300.0 57600.0 0.42 0.6369 0.9972 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I18 compound treatment 426310.0 33700.0 0.23 377760.0 -51000.0 -0.37 -0.1 -0.2306 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I19 compound treatment 105950.0 -287000.0 -1.94 75420.0 -353000.0 -2.56 -3.1782 -0.9906 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I20 compound treatment 377280.0 -15300.0 -0.1 306820.0 -122000.0 -0.88 -0.6974 -0.7847 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I21 mock treatment 381830.0 -10800.0 -0.07 479040.0 50300.0 0.36 0.2059 0.5546 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I22 mock treatment 295780.0 -96800.0 -0.65 455220.0 26500.0 0.19 -0.3271 -0.4799 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I23 compound treatment 318900.0 -73700.0 -0.5 432690.0 3940.0 0.03 -0.332 -0.6655 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 I24 compound treatment 304480.0 -88100.0 -0.6 483790.0 55000.0 0.4 -0.1393 -0.1945 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J01 compound treatment 144340.0 -248000.0 -1.68 399390.0 -29400.0 -0.21 -1.3365 -0.7904 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J02 compound treatment 446240.0 53600.0 0.36 372490.0 -56300.0 -0.41 -0.0317 -0.0582 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J03 compound treatment 244740.0 -148000.0 -1.0 264640.0 -164000.0 -1.19 -1.5465 -0.9963 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J04 compound treatment 384350.0 -8260.0 -0.06 363970.0 -64800.0 -0.47 -0.3711 -0.7857 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J05 mock treatment 245760.0 -147000.0 -0.99 394250.0 -34500.0 -0.25 -0.8782 -0.8583 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J06 mock treatment 416690.0 24100.0 0.16 297550.0 -131000.0 -0.95 -0.5565 -0.5776 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J07 compound treatment 400390.0 7780.0 0.05 278080.0 -151000.0 -1.09 -0.7341 -0.6723 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J08 compound treatment 133000.0 -260000.0 -1.75 153570.0 -275000.0 -1.99 -2.6489 -0.998 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J09 compound treatment 410310.0 17700.0 0.12 382880.0 -45900.0 -0.33 -0.1502 -0.4257 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J10 compound treatment 292760.0 -99900.0 -0.67 320970.0 -108000.0 -0.78 -1.0288 -0.9974 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J11 compound treatment 397950.0 5340.0 0.04 419150.0 -9600.0 -0.07 -0.0236 -0.3018 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J12 compound treatment 322110.0 -70500.0 -0.48 412080.0 -16700.0 -0.12 -0.4222 -0.8591 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J13 compound treatment 413920.0 21300.0 0.14 408550.0 -20200.0 -0.15 -0.0016 -0.0077 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J14 compound treatment 342980.0 -49600.0 -0.34 394090.0 -34700.0 -0.25 -0.4145 -0.9898 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J15 compound treatment 472540.0 79900.0 0.54 393280.0 -35500.0 -0.26 0.2003 0.335 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J16 compound treatment 345820.0 -46800.0 -0.32 345190.0 -83600.0 -0.6 -0.6513 -0.9542 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J17 compound treatment 400520.0 7910.0 0.05 320700.0 -108000.0 -0.78 -0.5153 -0.6573 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J18 compound treatment 391410.0 -1200.0 -0.01 483080.0 54300.0 0.39 0.2724 0.6924 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J19 compound treatment 318370.0 -74200.0 -0.5 339040.0 -89700.0 -0.65 -0.8139 -0.9919 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J20 compound treatment 252480.0 -140000.0 -0.95 288860.0 -140000.0 -1.01 -1.3856 -0.9994 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J21 mock treatment 444250.0 51600.0 0.35 336910.0 -91800.0 -0.66 -0.2234 -0.2975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J22 mock treatment 361600.0 -31000.0 -0.21 413340.0 -15400.0 -0.11 -0.227 -0.9564 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J23 compound treatment 264650.0 -128000.0 -0.86 420030.0 -8720.0 -0.06 -0.656 -0.7567 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 J24 compound treatment 303880.0 -88700.0 -0.6 315840.0 -113000.0 -0.82 -1.0019 -0.9884 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K01 compound treatment 424230.0 31600.0 0.21 403960.0 -24800.0 -0.18 0.0242 0.0867 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K02 compound treatment 322170.0 -70400.0 -0.48 331870.0 -96900.0 -0.7 -0.8325 -0.9822 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K03 compound treatment 327400.0 -65200.0 -0.44 537540.0 109000.0 0.79 0.2453 0.2718 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K04 compound treatment 203120.0 -189000.0 -1.28 440990.0 12200.0 0.09 -0.8427 -0.6566 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K05 compound treatment 49300.0 -343000.0 -2.32 45040.0 -384000.0 -2.78 -3.6044 -0.996 1107217 BCB03_000204 Cc1cccnc1I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K06 compound treatment 371840.0 -20800.0 -0.14 393500.0 -35200.0 -0.26 -0.2797 -0.9604 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K07 mock treatment 402460.0 9850.0 0.07 354020.0 -74700.0 -0.54 -0.3355 -0.6155 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K08 mock treatment 506360.0 114000.0 0.77 597560.0 169000.0 1.22 1.4076 0.975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K09 compound treatment 623050.0 230000.0 1.56 363520.0 -65200.0 -0.47 0.7671 0.4715 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K10 compound treatment 315540.0 -77100.0 -0.52 408680.0 -20100.0 -0.15 -0.471 -0.8711 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K11 compound treatment 396350.0 3740.0 0.03 410500.0 -18200.0 -0.13 -0.0756 -0.5617 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K12 compound treatment 453380.0 60800.0 0.41 269780.0 -159000.0 -1.15 -0.5234 -0.4284 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K13 compound treatment 451240.0 58600.0 0.4 308380.0 -120000.0 -0.87 -0.336 -0.3511 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K14 compound treatment 492320.0 99700.0 0.67 534310.0 106000.0 0.76 1.0167 0.998 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K15 mock treatment 433240.0 40600.0 0.27 437040.0 8290.0 0.06 0.2366 0.8418 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K16 mock treatment 479760.0 87100.0 0.59 445310.0 16600.0 0.12 0.5011 0.834 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K17 compound treatment 495040.0 102000.0 0.69 462920.0 34200.0 0.25 0.6643 0.9038 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K18 compound treatment 359250.0 -33400.0 -0.23 430200.0 1450.0 0.01 -0.152 -0.6734 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K19 compound treatment 493070.0 100000.0 0.68 500530.0 71800.0 0.52 0.8474 0.9913 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K20 compound treatment 318400.0 -74200.0 -0.5 357080.0 -71700.0 -0.52 -0.7214 -0.9999 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K21 compound treatment 539420.0 147000.0 0.99 459840.0 31100.0 0.23 0.8606 0.846 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K22 compound treatment 321290.0 -71300.0 -0.48 475410.0 46700.0 0.34 -0.1019 -0.1732 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K23 mock treatment 305250.0 -87400.0 -0.59 486820.0 58100.0 0.42 -0.1201 -0.1658 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 K24 mock treatment 401540.0 8930.0 0.06 438200.0 9450.0 0.07 0.091 0.998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L01 compound treatment 418940.0 26300.0 0.18 338200.0 -90500.0 -0.66 -0.3377 -0.4972 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L02 compound treatment 248800.0 -144000.0 -0.97 310320.0 -118000.0 -0.86 -1.2933 -0.998 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L03 compound treatment 495940.0 103000.0 0.7 494500.0 65800.0 0.48 0.8302 0.9826 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L04 compound treatment 292160.0 -100000.0 -0.68 289210.0 -140000.0 -1.01 -1.1942 -0.9813 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L05 compound treatment 537730.0 145000.0 0.98 251480.0 -177000.0 -1.28 -0.214 -0.1325 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L06 compound treatment 441560.0 48900.0 0.33 246600.0 -182000.0 -1.32 -0.6985 -0.5138 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L07 mock treatment 522190.0 130000.0 0.88 294080.0 -135000.0 -0.97 -0.0702 -0.0536 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L08 mock treatment 420480.0 27900.0 0.19 501690.0 72900.0 0.53 0.5065 0.9035 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L09 compound treatment 295250.0 -97400.0 -0.66 461410.0 32700.0 0.24 -0.298 -0.4263 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L10 compound treatment 409840.0 17200.0 0.12 386330.0 -42400.0 -0.31 -0.1348 -0.4105 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L11 compound treatment 314460.0 -78200.0 -0.53 477540.0 48800.0 0.35 -0.1236 -0.1946 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L12 compound treatment 321460.0 -71200.0 -0.48 374560.0 -54200.0 -0.39 -0.6173 -0.9949 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L13 compound treatment 438030.0 45400.0 0.31 404000.0 -24700.0 -0.18 0.0903 0.2542 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L14 compound treatment 302400.0 -90200.0 -0.61 333190.0 -95600.0 -0.69 -0.9202 -0.998 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L15 mock treatment 478790.0 86200.0 0.58 432010.0 3260.0 0.02 0.4284 0.7352 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L16 mock treatment 477700.0 85100.0 0.57 389810.0 -38900.0 -0.28 0.2072 0.3236 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L17 compound treatment 464480.0 71900.0 0.49 492380.0 63600.0 0.46 0.6691 0.9997 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L18 compound treatment 424260.0 31600.0 0.21 325850.0 -103000.0 -0.74 -0.3755 -0.4845 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L19 compound treatment 344920.0 -47700.0 -0.32 311040.0 -118000.0 -0.85 -0.8304 -0.9115 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L20 compound treatment 198320.0 -194000.0 -1.31 220250.0 -208000.0 -1.51 -1.9955 -0.9976 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L21 compound treatment 313440.0 -79200.0 -0.53 504760.0 76000.0 0.55 0.0108 0.0141 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L22 compound treatment 360690.0 -31900.0 -0.22 362960.0 -65800.0 -0.48 -0.4893 -0.9358 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L23 mock treatment 412000.0 19400.0 0.13 497310.0 68600.0 0.5 0.4436 0.8642 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 L24 mock treatment 296960.0 -95700.0 -0.65 253130.0 -176000.0 -1.27 -1.3559 -0.9508 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M01 compound treatment 492060.0 99400.0 0.67 515040.0 86300.0 0.62 0.9168 0.9993 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M02 compound treatment 437930.0 45300.0 0.31 517440.0 88700.0 0.64 0.6705 0.9426 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M03 compound treatment 441150.0 48500.0 0.33 573320.0 145000.0 1.05 0.9719 0.8862 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M04 compound treatment 602040.0 209000.0 1.42 460590.0 31800.0 0.23 1.1636 0.8116 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M05 compound treatment 489920.0 97300.0 0.66 565120.0 136000.0 0.99 1.163 0.9805 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M06 compound treatment 215360.0 -177000.0 -1.2 555930.0 127000.0 0.92 -0.1959 -0.1297 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M07 compound treatment 481490.0 88900.0 0.6 318840.0 -110000.0 -0.8 -0.1379 -0.1384 3000956 BCB03_000242 CCCc1cccc(=O)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M08 compound treatment 484040.0 91400.0 0.62 606180.0 177000.0 1.28 1.345 0.9437 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M09 mock treatment 398950.0 6340.0 0.04 448450.0 19700.0 0.14 0.1311 0.8806 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M10 mock treatment 431310.0 38700.0 0.26 555090.0 126000.0 0.91 0.8316 0.8742 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M11 compound treatment 478190.0 85600.0 0.58 388960.0 -39800.0 -0.29 0.2052 0.3177 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M12 compound treatment 350720.0 -41900.0 -0.28 425610.0 -3140.0 -0.02 -0.2162 -0.7614 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M13 mock treatment 483750.0 91100.0 0.62 525140.0 96400.0 0.7 0.9288 0.9981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M14 mock treatment 358670.0 -33900.0 -0.23 412720.0 -16000.0 -0.12 -0.2442 -0.9502 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M15 compound treatment 439520.0 46900.0 0.32 540020.0 111000.0 0.81 0.7937 0.9169 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M16 compound treatment 179950.0 -213000.0 -1.44 223150.0 -206000.0 -1.49 -2.0685 -0.9998 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M17 compound treatment 549020.0 156000.0 1.06 522240.0 93500.0 0.68 1.2258 0.9768 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M18 compound treatment 311070.0 -81500.0 -0.55 431720.0 2970.0 0.02 -0.3744 -0.679 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M19 compound treatment 412030.0 19400.0 0.13 476410.0 47700.0 0.35 0.3367 0.9123 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M20 compound treatment 429880.0 37300.0 0.25 521490.0 92700.0 0.67 0.6528 0.9104 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M21 compound treatment 289210.0 -103000.0 -0.7 412320.0 -16400.0 -0.12 -0.5781 -0.8157 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M22 compound treatment 112080.0 -281000.0 -1.9 169950.0 -259000.0 -1.87 -2.665 -1.0 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M23 compound treatment 389180.0 -3430.0 -0.02 424000.0 -4750.0 -0.03 -0.0407 -0.9816 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 M24 compound treatment 241850.0 -151000.0 -1.02 321560.0 -107000.0 -0.78 -1.269 -0.991 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N01 compound treatment 457340.0 64700.0 0.44 353660.0 -75100.0 -0.54 -0.0751 -0.1076 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N02 compound treatment 344850.0 -47800.0 -0.32 427870.0 -879.0 -0.01 -0.2327 -0.7209 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N03 compound treatment 361810.0 -30800.0 -0.21 429970.0 1220.0 0.01 -0.1409 -0.6765 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N04 compound treatment 281950.0 -111000.0 -0.75 426890.0 -1860.0 -0.01 -0.5382 -0.7197 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N05 compound treatment 405190.0 12600.0 0.08 399440.0 -29300.0 -0.21 -0.0899 -0.3935 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N06 compound treatment 176450.0 -216000.0 -1.46 258590.0 -170000.0 -1.23 -1.9038 -0.9964 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N07 compound treatment 196010.0 -197000.0 -1.33 423410.0 -5340.0 -0.04 -0.9667 -0.7274 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N08 compound treatment 323560.0 -69100.0 -0.47 288270.0 -140000.0 -1.02 -1.049 -0.9376 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N09 mock treatment 510240.0 118000.0 0.79 589220.0 160000.0 1.16 1.3834 0.9829 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N10 mock treatment 426240.0 33600.0 0.23 475870.0 47100.0 0.34 0.4019 0.9805 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N11 compound treatment 348800.0 -43800.0 -0.3 384530.0 -44200.0 -0.32 -0.4357 -0.9992 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N12 compound treatment 383780.0 -8830.0 -0.06 351540.0 -77200.0 -0.56 -0.4374 -0.7782 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N13 mock treatment 424960.0 32300.0 0.22 490590.0 61800.0 0.45 0.4711 0.9457 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N14 mock treatment 247060.0 -146000.0 -0.98 398360.0 -30400.0 -0.22 -0.851 -0.8444 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N15 compound treatment 442990.0 50400.0 0.34 436640.0 7890.0 0.06 0.2811 0.8144 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N16 compound treatment 399870.0 7260.0 0.05 432160.0 3410.0 0.02 0.0521 0.9496 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N17 compound treatment 391480.0 -1130.0 -0.01 344870.0 -83900.0 -0.61 -0.4348 -0.716 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N18 compound treatment 490130.0 97500.0 0.66 407650.0 -21100.0 -0.15 0.3579 0.5292 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N19 compound treatment 432820.0 40200.0 0.27 522140.0 93400.0 0.68 0.6701 0.9198 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N20 compound treatment 270310.0 -122000.0 -0.83 292360.0 -136000.0 -0.99 -1.2825 -0.9961 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N21 compound treatment 338330.0 -54300.0 -0.37 473680.0 44900.0 0.33 -0.0294 -0.0599 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N22 compound treatment 209460.0 -183000.0 -1.24 293780.0 -135000.0 -0.98 -1.5659 -0.9932 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N23 compound treatment 260410.0 -132000.0 -0.89 337840.0 -90900.0 -0.66 -1.097 -0.9887 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 N24 compound treatment 279330.0 -113000.0 -0.77 302130.0 -127000.0 -0.92 -1.1894 -0.996 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O01 compound treatment 327730.0 -64900.0 -0.44 313960.0 -115000.0 -0.83 -0.8976 -0.9554 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O02 compound treatment 228160.0 -164000.0 -1.11 366400.0 -62300.0 -0.45 -1.1049 -0.9212 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O03 compound treatment 285240.0 -107000.0 -0.73 493760.0 65000.0 0.47 -0.1802 -0.2084 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O04 compound treatment 269200.0 -123000.0 -0.83 212350.0 -216000.0 -1.57 -1.6973 -0.9564 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O05 compound treatment 261730.0 -131000.0 -0.88 440010.0 11300.0 0.08 -0.5677 -0.6392 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O06 compound treatment 230910.0 -162000.0 -1.09 471430.0 42700.0 0.31 -0.5541 -0.488 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O07 compound treatment 322950.0 -69700.0 -0.47 275240.0 -154000.0 -1.11 -1.1186 -0.9269 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O08 compound treatment 304610.0 -88000.0 -0.59 290590.0 -138000.0 -1.0 -1.1276 -0.9692 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O09 compound treatment 331710.0 -60900.0 -0.41 279410.0 -149000.0 -1.08 -1.0554 -0.9124 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O10 compound treatment 476260.0 83600.0 0.57 350720.0 -78000.0 -0.56 2.0E-4 3.0E-4 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O11 mock treatment 374670.0 -17900.0 -0.12 526100.0 97400.0 0.7 0.4126 0.577 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O12 mock treatment 382910.0 -9700.0 -0.07 402020.0 -26700.0 -0.19 -0.1832 -0.8966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O13 compound treatment 375960.0 -16700.0 -0.11 355160.0 -73600.0 -0.53 -0.4562 -0.838 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O14 compound treatment 355290.0 -37300.0 -0.25 393690.0 -35100.0 -0.25 -0.3578 -1.0 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O15 compound treatment 338660.0 -54000.0 -0.36 385470.0 -43300.0 -0.31 -0.4793 -0.9972 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O16 compound treatment 384160.0 -8450.0 -0.06 353860.0 -74900.0 -0.54 -0.4237 -0.7773 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O17 compound treatment 301860.0 -90800.0 -0.61 296060.0 -133000.0 -0.96 -1.1128 -0.9765 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O18 compound treatment 354080.0 -38500.0 -0.26 324010.0 -105000.0 -0.76 -0.7202 -0.8984 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O19 compound treatment 257070.0 -136000.0 -0.92 288160.0 -141000.0 -1.02 -1.3672 -0.9986 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O20 compound treatment 321140.0 -71500.0 -0.48 274400.0 -154000.0 -1.12 -1.1315 -0.9296 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O21 compound treatment 292990.0 -99600.0 -0.67 301310.0 -127000.0 -0.92 -1.1283 -0.988 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O22 compound treatment 306760.0 -85900.0 -0.58 236000.0 -193000.0 -1.4 -1.3968 -0.9244 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O23 compound treatment 231380.0 -161000.0 -1.09 275390.0 -153000.0 -1.11 -1.5553 -1.0 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 O24 compound treatment 322660.0 -70000.0 -0.47 277640.0 -151000.0 -1.09 -1.1077 -0.9296 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P01 compound treatment 311440.0 -81200.0 -0.55 296960.0 -132000.0 -0.95 -1.0624 -0.9654 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P02 compound treatment 215140.0 -177000.0 -1.2 221940.0 -207000.0 -1.5 -1.9065 -0.994 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P03 compound treatment 199110.0 -194000.0 -1.31 240690.0 -188000.0 -1.36 -1.8871 -0.9998 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P04 compound treatment 181980.0 -211000.0 -1.42 238440.0 -190000.0 -1.38 -1.9805 -0.9999 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P05 compound treatment 254720.0 -138000.0 -0.93 213630.0 -215000.0 -1.56 -1.7599 -0.9698 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P06 compound treatment 280880.0 -112000.0 -0.75 271000.0 -158000.0 -1.14 -1.3413 -0.9798 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P07 compound treatment 264240.0 -128000.0 -0.87 262590.0 -166000.0 -1.2 -1.4639 -0.9871 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P08 compound treatment 165440.0 -227000.0 -1.53 142240.0 -287000.0 -2.07 -2.5519 -0.989 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P09 compound treatment 274140.0 -118000.0 -0.8 251520.0 -177000.0 -1.28 -1.4732 -0.9742 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P10 compound treatment 185860.0 -207000.0 -1.4 165440.0 -263000.0 -1.91 -2.3356 -0.9883 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P11 mock treatment 355610.0 -37000.0 -0.25 263220.0 -166000.0 -1.2 -1.0241 -0.8366 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P12 mock treatment 359620.0 -33000.0 -0.22 301830.0 -127000.0 -0.92 -0.8073 -0.8539 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P13 compound treatment 196130.0 -196000.0 -1.33 187160.0 -242000.0 -1.75 -2.1754 -0.9908 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P14 compound treatment 259260.0 -133000.0 -0.9 304530.0 -124000.0 -0.9 -1.273 -1.0 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P15 compound treatment 178560.0 -214000.0 -1.45 184960.0 -244000.0 -1.76 -2.2706 -0.9951 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P16 compound treatment 267850.0 -125000.0 -0.84 228520.0 -200000.0 -1.45 -1.621 -0.9667 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P17 compound treatment 293950.0 -98700.0 -0.67 278730.0 -150000.0 -1.09 -1.2393 -0.9725 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P18 compound treatment 132280.0 -260000.0 -1.76 160240.0 -269000.0 -1.94 -2.6182 -0.9988 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P19 compound treatment 249120.0 -143000.0 -0.97 257490.0 -171000.0 -1.24 -1.5622 -0.9926 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P20 compound treatment 198400.0 -194000.0 -1.31 232370.0 -196000.0 -1.42 -1.9331 -0.9992 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P21 compound treatment 39130.0 -353000.0 -2.39 35650.0 -393000.0 -2.85 -3.701 -0.9962 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P22 compound treatment 193640.0 -199000.0 -1.34 191250.0 -237000.0 -1.72 -2.1663 -0.9926 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P23 compound treatment 221220.0 -171000.0 -1.16 200860.0 -228000.0 -1.65 -1.9854 -0.985 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2281 P24 compound treatment 50970.0 -342000.0 -2.31 51110.0 -378000.0 -2.73 -3.5653 -0.9965 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A01 compound treatment 385880.0 -37700.0 -0.25 229940.0 -114000.0 -0.83 -0.7633 -0.8841 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A02 compound treatment 252430.0 -171000.0 -1.16 391840.0 47900.0 0.35 -0.5722 -0.474 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A03 compound treatment 325350.0 -98200.0 -0.66 249090.0 -94800.0 -0.69 -0.9545 -0.9999 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A04 compound treatment 363430.0 -60100.0 -0.41 362900.0 19000.0 0.14 -0.19 -0.4431 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A05 compound treatment 351390.0 -72100.0 -0.49 276580.0 -67300.0 -0.49 -0.6894 -1.0 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A06 compound treatment 413180.0 -10400.0 -0.07 177240.0 -167000.0 -1.21 -0.9026 -0.7469 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A07 compound treatment 242180.0 -181000.0 -1.23 316590.0 -27300.0 -0.2 -1.0063 -0.8107 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A08 compound treatment 376130.0 -47400.0 -0.32 386080.0 42200.0 0.31 -0.0107 -0.0241 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A09 compound treatment 280320.0 -143000.0 -0.97 282260.0 -61700.0 -0.45 -0.9998 -0.9382 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A10 compound treatment 309040.0 -114000.0 -0.77 271680.0 -72200.0 -0.52 -0.9168 -0.9818 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A11 compound treatment 295230.0 -128000.0 -0.87 226170.0 -118000.0 -0.85 -1.2157 -1.0 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A12 compound treatment 308290.0 -115000.0 -0.78 286990.0 -56900.0 -0.41 -0.842 -0.9557 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A13 mock treatment 414480.0 -9060.0 -0.06 366920.0 23000.0 0.17 0.0745 0.4198 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A14 mock treatment 503130.0 79600.0 0.54 337070.0 -6840.0 -0.05 0.3453 0.6393 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A15 compound treatment 382580.0 -41000.0 -0.28 304480.0 -39400.0 -0.29 -0.3975 -0.9999 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A16 compound treatment 290480.0 -133000.0 -0.9 287680.0 -56200.0 -0.41 -0.9236 -0.9358 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A17 compound treatment 395840.0 -27700.0 -0.19 286830.0 -57100.0 -0.41 -0.4245 -0.9359 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A18 compound treatment 375050.0 -48500.0 -0.33 257660.0 -86300.0 -0.62 -0.6732 -0.9547 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A19 compound treatment 366080.0 -57500.0 -0.39 260580.0 -83300.0 -0.6 -0.7011 -0.9773 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A20 compound treatment 415460.0 -8080.0 -0.05 406100.0 62200.0 0.45 0.2797 0.6168 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A21 compound treatment 375430.0 -48100.0 -0.33 317040.0 -26900.0 -0.19 -0.3674 -0.9699 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A22 compound treatment 435530.0 12000.0 0.08 388280.0 44400.0 0.32 0.2844 0.8586 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A23 compound treatment 370050.0 -53500.0 -0.36 215840.0 -128000.0 -0.93 -0.9111 -0.9156 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 A24 compound treatment 316120.0 -107000.0 -0.73 442260.0 98300.0 0.71 -0.0098 -0.0096 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B01 compound treatment 287840.0 -136000.0 -0.92 284010.0 -59900.0 -0.43 -0.955 -0.9415 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B02 compound treatment 368700.0 -54800.0 -0.37 325920.0 -18000.0 -0.13 -0.3541 -0.9016 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B03 compound treatment 490770.0 67200.0 0.45 385800.0 41900.0 0.3 0.5356 0.9807 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B04 compound treatment 391450.0 -32100.0 -0.22 394570.0 50700.0 0.37 0.106 0.2488 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B05 compound treatment 480800.0 57300.0 0.39 479850.0 136000.0 0.98 0.9694 0.9168 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B06 compound treatment 297650.0 -126000.0 -0.85 352880.0 8970.0 0.06 -0.5556 -0.6512 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B07 compound treatment 515610.0 92100.0 0.62 278880.0 -65000.0 -0.47 0.107 0.1372 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B08 compound treatment 513120.0 89600.0 0.61 300240.0 -43700.0 -0.32 0.2045 0.2994 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B09 compound treatment 540090.0 117000.0 0.79 485230.0 141000.0 1.02 1.2802 0.9916 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B10 compound treatment 353710.0 -69800.0 -0.47 290900.0 -53000.0 -0.38 -0.605 -0.9947 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B11 compound treatment 433920.0 10400.0 0.07 393810.0 49900.0 0.36 0.305 0.8289 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B12 compound treatment 20320.0 -403000.0 -2.72 37520.0 -306000.0 -2.22 -3.4948 -0.9948 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B13 mock treatment 488030.0 64500.0 0.44 339840.0 -4070.0 -0.03 0.2873 0.6578 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B14 mock treatment 313540.0 -110000.0 -0.74 409930.0 66000.0 0.48 -0.1876 -0.2123 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B15 compound treatment 208210.0 -215000.0 -1.45 294350.0 -49600.0 -0.36 -1.2825 -0.8558 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B16 compound treatment 15680.0 -408000.0 -2.76 20290.0 -324000.0 -2.34 -3.6052 -0.9967 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B17 compound treatment 402120.0 -21400.0 -0.14 295130.0 -48800.0 -0.35 -0.352 -0.9224 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B18 compound treatment 306160.0 -117000.0 -0.79 234760.0 -109000.0 -0.79 -1.1195 -1.0 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B19 compound treatment 406920.0 -16600.0 -0.11 440340.0 96400.0 0.7 0.4142 0.5858 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B20 compound treatment 337280.0 -86300.0 -0.58 321370.0 -22500.0 -0.16 -0.5275 -0.8716 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B21 compound treatment 229630.0 -194000.0 -1.31 248170.0 -95700.0 -0.69 -1.4165 -0.9557 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B22 compound treatment 453570.0 30000.0 0.2 301650.0 -42300.0 -0.31 -0.0728 -0.1984 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B23 compound treatment 318560.0 -105000.0 -0.71 366240.0 22300.0 0.16 -0.3873 -0.5323 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 B24 compound treatment 435150.0 11600.0 0.08 317810.0 -26100.0 -0.19 -0.0781 -0.3819 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C01 compound treatment 259810.0 -164000.0 -1.11 305250.0 -38700.0 -0.28 -0.9802 -0.8589 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C02 compound treatment 504180.0 80600.0 0.54 423840.0 79900.0 0.58 0.7944 0.9995 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C03 compound treatment 334050.0 -89500.0 -0.6 348220.0 4310.0 0.03 -0.4055 -0.6697 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C04 compound treatment 363930.0 -59600.0 -0.4 235520.0 -108000.0 -0.78 -0.8396 -0.952 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C05 compound treatment 206050.0 -217000.0 -1.47 353440.0 9530.0 0.07 -0.9903 -0.6732 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C06 compound treatment 461530.0 38000.0 0.26 277490.0 -66400.0 -0.48 -0.1585 -0.2908 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C07 compound treatment 446080.0 22500.0 0.15 272680.0 -71200.0 -0.52 -0.2569 -0.4778 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C08 compound treatment 397780.0 -25800.0 -0.17 339850.0 -4060.0 -0.03 -0.1439 -0.815 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C09 compound treatment 322850.0 -101000.0 -0.68 397570.0 53700.0 0.39 -0.2064 -0.2635 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C10 compound treatment 407840.0 -15700.0 -0.11 277220.0 -66700.0 -0.48 -0.4164 -0.8424 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C11 mock treatment 304740.0 -119000.0 -0.8 294800.0 -49100.0 -0.36 -0.819 -0.9329 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C12 mock treatment 360170.0 -63400.0 -0.43 343380.0 -530.0 0.0 -0.3055 -0.7134 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C13 compound treatment 376370.0 -47200.0 -0.32 322940.0 -21000.0 -0.15 -0.3327 -0.9425 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C14 compound treatment 351170.0 -72400.0 -0.49 373530.0 29600.0 0.21 -0.1942 -0.3636 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C15 mock treatment 272990.0 -151000.0 -1.02 359900.0 16000.0 0.12 -0.6375 -0.6226 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C16 mock treatment 335450.0 -88100.0 -0.6 361650.0 17700.0 0.13 -0.3301 -0.5421 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C17 compound treatment 318240.0 -105000.0 -0.71 229070.0 -115000.0 -0.83 -1.0909 -0.997 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C18 compound treatment 329170.0 -94400.0 -0.64 351080.0 7170.0 0.05 -0.4142 -0.6474 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C19 compound treatment 361120.0 -62400.0 -0.42 319730.0 -24200.0 -0.18 -0.422 -0.9241 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C20 compound treatment 370880.0 -52700.0 -0.36 290270.0 -53600.0 -0.39 -0.5262 -0.999 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C21 compound treatment 268020.0 -156000.0 -1.05 372280.0 28400.0 0.21 -0.5978 -0.5584 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C22 compound treatment 427360.0 3820.0 0.03 325120.0 -18800.0 -0.14 -0.0779 -0.5629 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C23 compound treatment 256120.0 -167000.0 -1.13 300380.0 -43500.0 -0.32 -1.0227 -0.8709 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 C24 compound treatment 387840.0 -35700.0 -0.24 264320.0 -79600.0 -0.58 -0.578 -0.9253 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D01 compound treatment 258910.0 -165000.0 -1.11 403690.0 59800.0 0.43 -0.4806 -0.4026 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D02 compound treatment 364200.0 -59300.0 -0.4 436160.0 92200.0 0.67 0.1887 0.2422 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D03 compound treatment 202990.0 -221000.0 -1.49 306310.0 -37600.0 -0.27 -1.2462 -0.8226 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D04 compound treatment 406400.0 -17100.0 -0.12 356160.0 12200.0 0.09 -0.0192 -0.1316 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D05 compound treatment 381880.0 -41700.0 -0.28 463560.0 120000.0 0.87 0.4134 0.4539 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D06 compound treatment 527690.0 104000.0 0.7 331310.0 -12600.0 -0.09 0.4331 0.6103 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D07 compound treatment 405530.0 -18000.0 -0.12 337950.0 -5960.0 -0.04 -0.1166 -0.9028 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D08 compound treatment 477320.0 53800.0 0.36 324910.0 -19000.0 -0.14 0.1597 0.411 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D09 compound treatment 474020.0 50500.0 0.34 358680.0 14800.0 0.11 0.3168 0.8862 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D10 compound treatment 325780.0 -97800.0 -0.66 205730.0 -138000.0 -1.0 -1.1744 -0.9797 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D11 mock treatment 515150.0 91600.0 0.62 445540.0 102000.0 0.74 0.9579 0.9963 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D12 mock treatment 321030.0 -103000.0 -0.69 312340.0 -31600.0 -0.23 -0.6514 -0.8931 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D13 compound treatment 417760.0 -5780.0 -0.04 380290.0 36400.0 0.26 0.1586 0.5957 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D14 compound treatment 449640.0 26100.0 0.18 305380.0 -38500.0 -0.28 -0.0725 -0.2198 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D15 mock treatment 359680.0 -63900.0 -0.43 383570.0 39700.0 0.29 -0.1021 -0.197 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D16 mock treatment 519140.0 95600.0 0.65 333520.0 -10400.0 -0.08 0.4036 0.6206 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D17 compound treatment 245600.0 -178000.0 -1.2 184210.0 -160000.0 -1.16 -1.6676 -0.9998 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D18 compound treatment 400170.0 -23400.0 -0.16 265180.0 -78700.0 -0.57 -0.5147 -0.8702 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D19 compound treatment 290120.0 -133000.0 -0.9 322100.0 -21800.0 -0.16 -0.7491 -0.8185 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D20 compound treatment 334620.0 -88900.0 -0.6 189520.0 -154000.0 -1.12 -1.2151 -0.9576 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D21 compound treatment 186630.0 -237000.0 -1.6 131040.0 -213000.0 -1.54 -2.2215 -0.9998 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D22 compound treatment 374690.0 -48800.0 -0.33 218560.0 -125000.0 -0.91 -0.875 -0.9062 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D23 compound treatment 335210.0 -88300.0 -0.6 277300.0 -66600.0 -0.48 -0.763 -0.9944 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 D24 compound treatment 245560.0 -178000.0 -1.2 246100.0 -97800.0 -0.71 -1.351 -0.9681 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E01 mock treatment 480740.0 57200.0 0.39 446460.0 103000.0 0.74 0.7982 0.9537 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E02 mock treatment 522240.0 98700.0 0.67 377170.0 33300.0 0.24 0.6418 0.9052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E03 compound treatment 236400.0 -187000.0 -1.26 264840.0 -79100.0 -0.57 -1.2989 -0.9358 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E04 compound treatment 533050.0 110000.0 0.74 448320.0 104000.0 0.76 1.0577 0.9999 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E05 compound treatment 508320.0 84800.0 0.57 441760.0 97800.0 0.71 0.9059 0.9945 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E06 compound treatment 441350.0 17800.0 0.12 325410.0 -18500.0 -0.13 -0.0096 -0.0533 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E07 compound treatment 287330.0 -136000.0 -0.92 373210.0 29300.0 0.21 -0.5008 -0.5303 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E08 compound treatment 554140.0 131000.0 0.88 262400.0 -81500.0 -0.59 0.2068 0.1948 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E09 mock treatment 414970.0 -8570.0 -0.06 344650.0 740.0 0.01 -0.0372 -0.639 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E10 mock treatment 531200.0 108000.0 0.73 407580.0 63700.0 0.46 0.8403 0.9758 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E11 compound treatment 318370.0 -105000.0 -0.71 302160.0 -41800.0 -0.3 -0.7162 -0.9274 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E12 compound treatment 339590.0 -83900.0 -0.57 270240.0 -73700.0 -0.53 -0.7782 -0.9995 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E13 compound treatment 403920.0 -19600.0 -0.13 326680.0 -17200.0 -0.12 -0.1819 -0.9995 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E14 compound treatment 422770.0 -770.0 -0.01 280380.0 -63500.0 -0.46 -0.3289 -0.7151 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E15 compound treatment 540340.0 117000.0 0.79 272520.0 -71400.0 -0.52 0.1926 0.2042 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E16 compound treatment 486880.0 63300.0 0.43 295960.0 -48000.0 -0.35 0.0572 0.1038 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E17 mock treatment 448160.0 24600.0 0.17 312640.0 -31300.0 -0.23 -0.0424 -0.1511 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E18 mock treatment 297140.0 -126000.0 -0.85 372480.0 28600.0 0.21 -0.4577 -0.5208 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E19 compound treatment 344160.0 -79400.0 -0.54 297600.0 -46300.0 -0.34 -0.6163 -0.9744 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E20 compound treatment 399580.0 -24000.0 -0.16 332580.0 -11300.0 -0.08 -0.1725 -0.9503 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E21 compound treatment 367680.0 -55900.0 -0.38 203750.0 -140000.0 -1.01 -0.9843 -0.9093 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E22 compound treatment 233600.0 -190000.0 -1.28 198570.0 -145000.0 -1.05 -1.6514 -0.9951 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E23 compound treatment 326240.0 -97300.0 -0.66 352570.0 8660.0 0.06 -0.4206 -0.6368 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 E24 compound treatment 297640.0 -126000.0 -0.85 231300.0 -113000.0 -0.82 -1.1779 -0.9998 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F01 mock treatment 329730.0 -93800.0 -0.63 215050.0 -129000.0 -0.93 -1.1078 -0.9823 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F02 mock treatment 527560.0 104000.0 0.7 465180.0 121000.0 0.88 1.1177 0.9939 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F03 compound treatment 322400.0 -101000.0 -0.68 233600.0 -110000.0 -0.8 -1.0479 -0.997 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F04 compound treatment 452350.0 28800.0 0.19 236930.0 -107000.0 -0.77 -0.41 -0.5134 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F05 compound treatment 270530.0 -153000.0 -1.03 181940.0 -162000.0 -1.17 -1.5601 -0.998 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F06 compound treatment 376800.0 -46700.0 -0.32 337770.0 -6140.0 -0.04 -0.2547 -0.7988 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F07 compound treatment 320580.0 -103000.0 -0.7 358610.0 14700.0 0.11 -0.4167 -0.5921 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F08 compound treatment 566400.0 143000.0 0.97 440320.0 96400.0 0.7 1.176 0.9873 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F09 mock treatment 582200.0 159000.0 1.07 237800.0 -106000.0 -0.77 0.2149 0.1629 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F10 mock treatment 563680.0 140000.0 0.95 417950.0 74000.0 0.54 1.0485 0.9637 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F11 compound treatment 218130.0 -205000.0 -1.39 48000.0 -296000.0 -2.14 -2.4961 -0.9779 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F12 compound treatment 278620.0 -145000.0 -0.98 168640.0 -175000.0 -1.27 -1.5896 -0.9918 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F13 compound treatment 294930.0 -129000.0 -0.87 338730.0 -5180.0 -0.04 -0.641 -0.7369 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F14 compound treatment 278350.0 -145000.0 -0.98 366280.0 22400.0 0.16 -0.5792 -0.5825 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F15 compound treatment 412540.0 -11000.0 -0.07 265440.0 -78500.0 -0.57 -0.4542 -0.7929 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F16 compound treatment 512960.0 89400.0 0.6 377230.0 33300.0 0.24 0.5978 0.9189 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F17 mock treatment 568210.0 145000.0 0.98 291360.0 -52600.0 -0.38 0.4222 0.4025 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F18 mock treatment 431430.0 7890.0 0.05 404440.0 60500.0 0.44 0.3475 0.7873 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F19 compound treatment 549070.0 126000.0 0.85 384160.0 40200.0 0.29 0.8058 0.8985 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F20 compound treatment 257310.0 -166000.0 -1.12 226460.0 -117000.0 -0.85 -1.3954 -0.9906 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F21 compound treatment 415520.0 -8020.0 -0.05 319360.0 -24600.0 -0.18 -0.164 -0.8826 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F22 compound treatment 340640.0 -82900.0 -0.56 257780.0 -86100.0 -0.62 -0.837 -0.9986 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F23 compound treatment 228520.0 -195000.0 -1.32 211040.0 -133000.0 -0.96 -1.6119 -0.988 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 F24 compound treatment 208800.0 -215000.0 -1.45 272160.0 -71800.0 -0.52 -1.3933 -0.9041 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G01 compound treatment 465760.0 42200.0 0.29 285120.0 -58800.0 -0.43 -0.0992 -0.1936 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G02 compound treatment 505530.0 82000.0 0.55 315010.0 -28900.0 -0.21 0.2438 0.4117 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G03 mock treatment 510770.0 87200.0 0.59 463210.0 119000.0 0.86 1.0274 0.9827 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G04 mock treatment 499520.0 76000.0 0.51 494990.0 151000.0 1.09 1.1363 0.9406 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G05 compound treatment 316010.0 -108000.0 -0.73 445960.0 102000.0 0.74 0.0086 0.0083 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G06 compound treatment 319890.0 -104000.0 -0.7 465350.0 121000.0 0.88 0.1264 0.1125 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G07 compound treatment 304540.0 -119000.0 -0.8 374430.0 30500.0 0.22 -0.4123 -0.4945 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G08 compound treatment 504060.0 80500.0 0.54 245290.0 -98600.0 -0.71 -0.1201 -0.1338 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G09 compound treatment 351800.0 -71700.0 -0.48 299100.0 -44800.0 -0.32 -0.5721 -0.9809 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G10 compound treatment 597470.0 174000.0 1.18 414240.0 70300.0 0.51 1.191 0.9299 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G11 compound treatment 232760.0 -191000.0 -1.29 258240.0 -85700.0 -0.62 -1.35 -0.9438 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G12 compound treatment 347080.0 -76500.0 -0.52 233320.0 -111000.0 -0.8 -0.9314 -0.9775 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G13 compound treatment 464640.0 41100.0 0.28 272840.0 -71100.0 -0.51 -0.1674 -0.2864 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G14 compound treatment 444160.0 20600.0 0.14 357540.0 13600.0 0.1 0.1683 0.9857 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G15 compound treatment 398880.0 -24700.0 -0.17 265950.0 -78000.0 -0.56 -0.5169 -0.8784 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G16 compound treatment 463940.0 40400.0 0.27 288390.0 -55500.0 -0.4 -0.0912 -0.1876 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G17 compound treatment 380580.0 -43000.0 -0.29 305480.0 -38400.0 -0.28 -0.402 -0.9998 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G18 compound treatment 426720.0 3180.0 0.02 238300.0 -106000.0 -0.76 -0.5254 -0.687 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G19 mock treatment 553680.0 130000.0 0.88 248400.0 -95500.0 -0.69 0.1329 0.1188 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G20 mock treatment 620930.0 197000.0 1.33 457950.0 114000.0 0.83 1.5268 0.9734 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G21 compound treatment 341990.0 -81500.0 -0.55 221840.0 -122000.0 -0.88 -1.0145 -0.9742 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G22 compound treatment 562800.0 139000.0 0.94 350880.0 6970.0 0.05 0.701 0.744 3071255 BCB03_000457 NC(=N)NCC#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G23 compound treatment 272420.0 -151000.0 -1.02 279220.0 -64700.0 -0.47 -1.0532 -0.9375 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 G24 compound treatment 387960.0 -35600.0 -0.24 309600.0 -34300.0 -0.25 -0.3456 -0.9999 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H01 compound treatment 379040.0 -44500.0 -0.3 214830.0 -129000.0 -0.93 -0.8733 -0.8897 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H02 compound treatment 489480.0 65900.0 0.45 390280.0 46400.0 0.34 0.5524 0.9903 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H03 mock treatment 261090.0 -162000.0 -1.1 468810.0 125000.0 0.9 -0.1368 -0.0962 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H04 mock treatment 279870.0 -144000.0 -0.97 364650.0 20700.0 0.15 -0.5803 -0.5907 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H05 compound treatment 414590.0 -8950.0 -0.06 275760.0 -68200.0 -0.49 -0.3916 -0.7879 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H06 compound treatment 304880.0 -119000.0 -0.8 400080.0 56200.0 0.41 -0.2794 -0.3108 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H07 compound treatment 504850.0 81300.0 0.55 341760.0 -2150.0 -0.02 0.3775 0.6868 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H08 compound treatment 447060.0 23500.0 0.16 404450.0 60500.0 0.44 0.4223 0.9058 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H09 compound treatment 57780.0 -366000.0 -2.47 27680.0 -316000.0 -2.29 -3.3662 -0.9993 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H10 compound treatment 357930.0 -65600.0 -0.44 346610.0 2700.0 0.02 -0.2997 -0.6753 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H11 compound treatment 514370.0 90800.0 0.61 256090.0 -87800.0 -0.64 -0.0156 -0.0176 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H12 compound treatment 496160.0 72600.0 0.49 389920.0 46000.0 0.33 0.5825 0.9822 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H13 compound treatment 224230.0 -199000.0 -1.35 297460.0 -46500.0 -0.34 -1.19 -0.8573 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H14 compound treatment 329120.0 -94400.0 -0.64 422020.0 78100.0 0.57 -0.0513 -0.0602 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H15 compound treatment 357070.0 -66500.0 -0.45 392860.0 48900.0 0.35 -0.067 -0.1172 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H16 compound treatment 349770.0 -73800.0 -0.5 292850.0 -51100.0 -0.37 -0.6138 -0.9892 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H17 compound treatment 430420.0 6880.0 0.05 368510.0 24600.0 0.18 0.1588 0.8628 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H18 compound treatment 370160.0 -53400.0 -0.36 426790.0 82900.0 0.6 0.1692 0.2417 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H19 mock treatment 525820.0 102000.0 0.69 370210.0 26300.0 0.19 0.6233 0.8695 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H20 mock treatment 476570.0 53000.0 0.36 226880.0 -117000.0 -0.85 -0.3457 -0.3758 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H21 compound treatment 263100.0 -160000.0 -1.08 337670.0 -6240.0 -0.05 -0.7985 -0.7359 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H22 compound treatment 391520.0 -32000.0 -0.22 327260.0 -16700.0 -0.12 -0.2382 -0.9618 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H23 compound treatment 360410.0 -63100.0 -0.43 326850.0 -17100.0 -0.12 -0.3889 -0.8759 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 H24 compound treatment 424960.0 1420.0 0.01 192650.0 -151000.0 -1.09 -0.7675 -0.7009 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I01 compound treatment 432970.0 9430.0 0.06 288070.0 -55800.0 -0.4 -0.2408 -0.5884 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I02 compound treatment 526920.0 103000.0 0.7 284000.0 -59900.0 -0.43 0.1873 0.2278 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I03 compound treatment 298210.0 -125000.0 -0.85 411840.0 67900.0 0.49 -0.2511 -0.2564 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I04 compound treatment 464080.0 40500.0 0.27 271600.0 -72300.0 -0.52 -0.1764 -0.2987 1035256 BCB03_000483 C#CCNCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I05 mock treatment 425390.0 1850.0 0.01 268500.0 -75400.0 -0.55 -0.3772 -0.6907 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I06 mock treatment 225840.0 -198000.0 -1.34 353830.0 9920.0 0.07 -0.8938 -0.6681 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I07 compound treatment 355780.0 -67800.0 -0.46 441670.0 97800.0 0.71 0.1767 0.2096 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I08 compound treatment 244160.0 -179000.0 -1.21 293840.0 -50100.0 -0.36 -1.1133 -0.8801 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I09 compound treatment 267680.0 -156000.0 -1.05 205450.0 -138000.0 -1.0 -1.4534 -0.9997 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I10 compound treatment 527540.0 104000.0 0.7 306160.0 -37800.0 -0.27 0.3037 0.4027 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I11 compound treatment 491520.0 68000.0 0.46 235360.0 -109000.0 -0.79 -0.2308 -0.2536 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I12 compound treatment 267800.0 -156000.0 -1.05 367590.0 23700.0 0.17 -0.6229 -0.5842 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I13 compound treatment 507420.0 83900.0 0.57 388230.0 44300.0 0.32 0.6276 0.9637 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I14 compound treatment 481060.0 57500.0 0.39 149140.0 -195000.0 -1.41 -0.7222 -0.4938 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I15 compound treatment 337840.0 -85700.0 -0.58 263480.0 -80400.0 -0.58 -0.8212 -1.0 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I16 compound treatment 373810.0 -49700.0 -0.34 243810.0 -100000.0 -0.72 -0.75 -0.939 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I17 compound treatment 396900.0 -26600.0 -0.18 288600.0 -55300.0 -0.4 -0.4104 -0.9349 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I18 compound treatment 370080.0 -53500.0 -0.36 346150.0 2240.0 0.02 -0.244 -0.6747 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I19 compound treatment 309120.0 -114000.0 -0.77 231400.0 -113000.0 -0.81 -1.1226 -0.9997 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I20 compound treatment 423570.0 30.2 0.0 411400.0 67500.0 0.49 0.3456 0.7074 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I21 mock treatment 403320.0 -20200.0 -0.14 273400.0 -70500.0 -0.51 -0.4575 -0.8659 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I22 mock treatment 332220.0 -91300.0 -0.62 302640.0 -41300.0 -0.3 -0.6476 -0.9446 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I23 compound treatment 204970.0 -219000.0 -1.48 230830.0 -113000.0 -0.82 -1.6231 -0.9613 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 I24 compound treatment 211300.0 -212000.0 -1.43 296160.0 -47800.0 -0.35 -1.2585 -0.8531 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J01 compound treatment 237170.0 -186000.0 -1.26 254950.0 -89000.0 -0.64 -1.3458 -0.9515 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J02 compound treatment 345450.0 -78100.0 -0.53 287730.0 -56200.0 -0.41 -0.6607 -0.9917 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J03 compound treatment 484670.0 61100.0 0.41 391300.0 47400.0 0.34 0.5346 0.9957 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J04 compound treatment 273700.0 -150000.0 -1.01 320960.0 -23000.0 -0.17 -0.8334 -0.8123 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J05 mock treatment 341050.0 -82500.0 -0.56 264210.0 -79700.0 -0.58 -0.8021 -0.9999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J06 mock treatment 348070.0 -75500.0 -0.51 143450.0 -200000.0 -1.45 -1.3867 -0.9015 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J07 compound treatment 348350.0 -75200.0 -0.51 211740.0 -132000.0 -0.96 -1.0358 -0.9561 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J08 compound treatment 410000.0 -13500.0 -0.09 349940.0 6030.0 0.04 -0.0338 -0.3337 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J09 compound treatment 294720.0 -129000.0 -0.87 377970.0 34100.0 0.25 -0.4411 -0.4876 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J10 compound treatment 276960.0 -147000.0 -0.99 269700.0 -74200.0 -0.54 -1.0802 -0.9587 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J11 compound treatment 335360.0 -88200.0 -0.6 223570.0 -120000.0 -0.87 -1.0373 -0.9828 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J12 compound treatment 422120.0 -1420.0 -0.01 379150.0 35200.0 0.26 0.1736 0.68 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J13 compound treatment 388390.0 -35100.0 -0.24 315040.0 -28900.0 -0.21 -0.3157 -0.998 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J14 compound treatment 430460.0 6920.0 0.05 389920.0 46000.0 0.33 0.2686 0.7985 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J15 compound treatment 190050.0 -233000.0 -1.58 122050.0 -222000.0 -1.61 -2.2512 -1.0 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J16 compound treatment 424380.0 840.0 0.01 350080.0 6170.0 0.04 0.0356 0.7906 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J17 compound treatment 357180.0 -66400.0 -0.45 293500.0 -50400.0 -0.36 -0.5751 -0.9948 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J18 compound treatment 404960.0 -18600.0 -0.13 352120.0 8210.0 0.06 -0.0467 -0.3366 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J19 compound treatment 142030.0 -282000.0 -1.9 112170.0 -232000.0 -1.68 -2.5312 -0.998 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J20 compound treatment 381700.0 -41800.0 -0.28 311730.0 -32200.0 -0.23 -0.3646 -0.9954 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J21 mock treatment 472160.0 48600.0 0.33 318490.0 -25400.0 -0.18 0.1022 0.2714 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J22 mock treatment 403920.0 -19600.0 -0.13 260650.0 -83300.0 -0.6 -0.5199 -0.8425 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J23 compound treatment 298000.0 -126000.0 -0.85 331780.0 -12100.0 -0.09 -0.6619 -0.7762 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 J24 compound treatment 287240.0 -136000.0 -0.92 276990.0 -66900.0 -0.48 -0.9938 -0.955 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K01 compound treatment 123390.0 -300000.0 -2.03 211740.0 -132000.0 -0.96 -2.1106 -0.9412 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K02 compound treatment 313850.0 -110000.0 -0.74 369220.0 25300.0 0.18 -0.3945 -0.5168 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K03 compound treatment 241410.0 -182000.0 -1.23 413890.0 70000.0 0.51 -0.512 -0.3847 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K04 compound treatment 491690.0 68200.0 0.46 297840.0 -46100.0 -0.33 0.0898 0.1579 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K05 compound treatment 283410.0 -140000.0 -0.95 315200.0 -28700.0 -0.21 -0.8165 -0.8423 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K06 compound treatment 393860.0 -29700.0 -0.2 176600.0 -167000.0 -1.21 -0.9982 -0.8131 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K07 mock treatment 173800.0 -250000.0 -1.69 248440.0 -95500.0 -0.69 -1.6819 -0.9223 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K08 mock treatment 433170.0 9630.0 0.07 464450.0 121000.0 0.87 0.663 0.7577 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K09 compound treatment 399530.0 -24000.0 -0.16 229570.0 -114000.0 -0.83 -0.7 -0.8299 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K10 compound treatment 423800.0 260.0 0.0 413550.0 69600.0 0.5 0.3577 0.7096 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K11 compound treatment 193930.0 -230000.0 -1.55 233190.0 -111000.0 -0.8 -1.6638 -0.9528 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K12 compound treatment 582160.0 159000.0 1.07 362300.0 18400.0 0.13 0.852 0.7889 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K13 compound treatment 282410.0 -141000.0 -0.95 267330.0 -76600.0 -0.55 -1.0663 -0.9667 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K14 compound treatment 488900.0 65400.0 0.44 442340.0 98400.0 0.71 0.8161 0.9735 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K15 mock treatment 463130.0 39600.0 0.27 380360.0 36400.0 0.26 0.3757 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K16 mock treatment 405510.0 -18000.0 -0.12 324880.0 -19000.0 -0.14 -0.1836 -0.9981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K17 compound treatment 479410.0 55900.0 0.38 468540.0 125000.0 0.9 0.9049 0.9253 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K18 compound treatment 443910.0 20400.0 0.14 353490.0 9580.0 0.07 0.1464 0.9496 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K19 compound treatment 382050.0 -41500.0 -0.28 504860.0 161000.0 1.17 0.6256 0.5221 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K20 compound treatment 476690.0 53200.0 0.36 380800.0 36900.0 0.27 0.4428 0.9894 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K21 compound treatment 450650.0 27100.0 0.18 430880.0 87000.0 0.63 0.5747 0.8765 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K22 compound treatment 343400.0 -80100.0 -0.54 402450.0 58500.0 0.42 -0.0832 -0.1211 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K23 mock treatment 338620.0 -84900.0 -0.57 257120.0 -86800.0 -0.63 -0.85 -0.999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 K24 mock treatment 526080.0 103000.0 0.69 382260.0 38300.0 0.28 0.6862 0.9194 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L01 compound treatment 313980.0 -110000.0 -0.74 292590.0 -51300.0 -0.37 -0.7861 -0.9491 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L02 compound treatment 398050.0 -25500.0 -0.17 239520.0 -104000.0 -0.76 -0.6561 -0.8466 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L03 compound treatment 357600.0 -65900.0 -0.45 305770.0 -38100.0 -0.28 -0.5103 -0.9735 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L04 compound treatment 393290.0 -30200.0 -0.2 303040.0 -40900.0 -0.3 -0.3537 -0.9837 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L05 compound treatment 495410.0 71900.0 0.49 164640.0 -179000.0 -1.3 -0.5742 -0.4144 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L06 compound treatment 493880.0 70300.0 0.48 379850.0 35900.0 0.26 0.52 0.9598 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L07 mock treatment 338400.0 -85100.0 -0.58 250560.0 -93400.0 -0.68 -0.8846 -0.9968 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L08 mock treatment 437920.0 14400.0 0.1 319240.0 -24700.0 -0.18 -0.0576 -0.2832 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L09 compound treatment 517760.0 94200.0 0.64 453340.0 109000.0 0.79 1.0103 0.9941 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L10 compound treatment 385450.0 -38100.0 -0.26 284970.0 -58900.0 -0.43 -0.4837 -0.9707 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L11 compound treatment 453190.0 29700.0 0.2 334720.0 -9190.0 -0.07 0.0946 0.4482 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L12 compound treatment 296770.0 -127000.0 -0.86 274100.0 -69800.0 -0.51 -0.963 -0.9683 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L13 compound treatment 368380.0 -55200.0 -0.37 326910.0 -17000.0 -0.12 -0.3506 -0.8932 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L14 compound treatment 419650.0 -3890.0 -0.03 309970.0 -33900.0 -0.25 -0.1923 -0.7783 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L15 mock treatment 551840.0 128000.0 0.87 354280.0 10400.0 0.08 0.6661 0.7655 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L16 mock treatment 411290.0 -12200.0 -0.08 381930.0 38000.0 0.28 0.1361 0.4735 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L17 compound treatment 432210.0 8670.0 0.06 370810.0 26900.0 0.19 0.1791 0.8808 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L18 compound treatment 508720.0 85200.0 0.58 282820.0 -61100.0 -0.44 0.0943 0.1299 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L19 compound treatment 337280.0 -86300.0 -0.58 345320.0 1410.0 0.01 -0.4049 -0.6946 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L20 compound treatment 396160.0 -27400.0 -0.19 381950.0 38000.0 0.28 0.0639 0.1926 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L21 compound treatment 350770.0 -72800.0 -0.49 248710.0 -95200.0 -0.69 -0.835 -0.9863 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L22 compound treatment 377830.0 -45700.0 -0.31 398560.0 54600.0 0.4 0.0613 0.1222 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L23 mock treatment 385060.0 -38500.0 -0.26 445030.0 101000.0 0.73 0.3338 0.4296 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 L24 mock treatment 421790.0 -1750.0 -0.01 265280.0 -78600.0 -0.57 -0.4108 -0.7216 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M01 compound treatment 401630.0 -21900.0 -0.15 459550.0 116000.0 0.84 0.4872 0.5732 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M02 compound treatment 497530.0 74000.0 0.5 377770.0 33900.0 0.25 0.5268 0.9462 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M03 compound treatment 476970.0 53400.0 0.36 240090.0 -104000.0 -0.75 -0.2761 -0.3312 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M04 compound treatment 525880.0 102000.0 0.69 365450.0 21500.0 0.16 0.5992 0.8453 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M05 compound treatment 425210.0 1670.0 0.01 360560.0 16600.0 0.12 0.0932 0.7699 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M06 compound treatment 516030.0 92500.0 0.62 340640.0 -3270.0 -0.02 0.4252 0.6798 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M07 compound treatment 289440.0 -134000.0 -0.91 405690.0 61800.0 0.45 -0.3245 -0.3211 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M08 compound treatment 259410.0 -164000.0 -1.11 269870.0 -74000.0 -0.54 -1.1632 -0.9443 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M09 mock treatment 543200.0 120000.0 0.81 245970.0 -97900.0 -0.71 0.0704 0.0655 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M10 mock treatment 531720.0 108000.0 0.73 377010.0 33100.0 0.24 0.6863 0.8922 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M11 compound treatment 321490.0 -102000.0 -0.69 346470.0 2560.0 0.02 -0.4745 -0.6879 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M12 compound treatment 467220.0 43700.0 0.3 373860.0 29900.0 0.22 0.362 0.9885 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M13 mock treatment 446400.0 22900.0 0.15 391050.0 47100.0 0.34 0.3505 0.9358 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M14 mock treatment 535150.0 112000.0 0.75 393950.0 50000.0 0.36 0.7894 0.9435 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M15 compound treatment 417710.0 -5830.0 -0.04 382040.0 38100.0 0.28 0.1673 0.6001 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M16 compound treatment 482010.0 58500.0 0.4 443050.0 99100.0 0.72 0.7868 0.9605 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M17 compound treatment 387040.0 -36500.0 -0.25 369890.0 26000.0 0.19 -0.0414 -0.1335 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M18 compound treatment 395840.0 -27700.0 -0.19 344610.0 700.0 0.01 -0.1288 -0.6877 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M19 compound treatment 412720.0 -10800.0 -0.07 361920.0 18000.0 0.13 0.0405 0.2709 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M20 compound treatment 403520.0 -20000.0 -0.14 410080.0 66200.0 0.48 0.2431 0.4883 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M21 compound treatment 377330.0 -46200.0 -0.31 330650.0 -13300.0 -0.1 -0.2887 -0.8837 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M22 compound treatment 374210.0 -49300.0 -0.33 297050.0 -46900.0 -0.34 -0.4756 -1.0 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M23 compound treatment 416180.0 -7360.0 -0.05 298780.0 -45100.0 -0.33 -0.2662 -0.8055 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 M24 compound treatment 407560.0 -16000.0 -0.11 368050.0 24100.0 0.17 0.0472 0.2299 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N01 compound treatment 386360.0 -37200.0 -0.25 390180.0 46300.0 0.33 0.0592 0.1414 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N02 compound treatment 259680.0 -164000.0 -1.11 336640.0 -7270.0 -0.05 -0.8201 -0.7399 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N03 compound treatment 333760.0 -89800.0 -0.61 234450.0 -109000.0 -0.79 -0.9892 -0.9913 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N04 compound treatment 262370.0 -161000.0 -1.09 164890.0 -179000.0 -1.3 -1.6864 -0.9963 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N05 compound treatment 253180.0 -170000.0 -1.15 235220.0 -109000.0 -0.79 -1.3703 -0.9828 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N06 compound treatment 219480.0 -204000.0 -1.38 222720.0 -121000.0 -0.88 -1.5953 -0.9762 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N07 compound treatment 211150.0 -212000.0 -1.44 202600.0 -141000.0 -1.02 -1.7381 -0.9862 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N08 compound treatment 331630.0 -91900.0 -0.62 229340.0 -115000.0 -0.83 -1.0256 -0.9898 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N09 mock treatment 477930.0 54400.0 0.37 323950.0 -20000.0 -0.14 0.1577 0.3993 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N10 mock treatment 389700.0 -33800.0 -0.23 385550.0 41600.0 0.3 0.0515 0.136 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N11 compound treatment 213460.0 -210000.0 -1.42 184450.0 -159000.0 -1.15 -1.8199 -0.9947 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N12 compound treatment 184850.0 -239000.0 -1.61 145310.0 -199000.0 -1.44 -2.157 -0.9984 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N13 mock treatment 355690.0 -67800.0 -0.46 375240.0 31300.0 0.23 -0.1638 -0.3203 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N14 mock treatment 414050.0 -9490.0 -0.06 319520.0 -24400.0 -0.18 -0.1702 -0.906 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N15 compound treatment 277670.0 -146000.0 -0.99 201760.0 -142000.0 -1.03 -1.4246 -0.9998 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N16 compound treatment 226750.0 -197000.0 -1.33 182960.0 -161000.0 -1.17 -1.7641 -0.9978 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N17 compound treatment 186740.0 -237000.0 -1.6 252080.0 -91800.0 -0.66 -1.6014 -0.9243 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N18 compound treatment 149250.0 -274000.0 -1.85 92230.0 -252000.0 -1.82 -2.5988 -1.0 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N19 compound treatment 267750.0 -156000.0 -1.05 227520.0 -116000.0 -0.84 -1.3401 -0.9939 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N20 compound treatment 232440.0 -191000.0 -1.29 214500.0 -129000.0 -0.94 -1.5755 -0.9876 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N21 compound treatment 257450.0 -166000.0 -1.12 215930.0 -128000.0 -0.93 -1.4486 -0.9955 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N22 compound treatment 268000.0 -156000.0 -1.05 202250.0 -142000.0 -1.03 -1.4683 -0.9999 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N23 compound treatment 360480.0 -63100.0 -0.43 173920.0 -170000.0 -1.23 -1.1714 -0.8995 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 N24 compound treatment 284320.0 -139000.0 -0.94 227520.0 -116000.0 -0.84 -1.2609 -0.9985 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O01 compound treatment 208120.0 -215000.0 -1.46 241280.0 -103000.0 -0.74 -1.5546 -0.9513 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O02 compound treatment 236800.0 -187000.0 -1.26 388660.0 44700.0 0.32 -0.6631 -0.5091 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O03 compound treatment 151960.0 -272000.0 -1.84 280860.0 -63100.0 -0.46 -1.6203 -0.8569 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O04 compound treatment 355640.0 -67900.0 -0.46 221360.0 -123000.0 -0.89 -0.9517 -0.9529 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O05 compound treatment 391410.0 -32100.0 -0.22 232160.0 -112000.0 -0.81 -0.7255 -0.8662 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O06 compound treatment 429520.0 5980.0 0.04 289760.0 -54200.0 -0.39 -0.2486 -0.6309 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O07 compound treatment 311370.0 -112000.0 -0.76 283760.0 -60200.0 -0.44 -0.8438 -0.9654 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O08 compound treatment 314560.0 -109000.0 -0.74 299650.0 -44300.0 -0.32 -0.7472 -0.9305 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O09 compound treatment 304830.0 -119000.0 -0.8 269940.0 -74000.0 -0.54 -0.9458 -0.9807 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O10 compound treatment 237850.0 -186000.0 -1.25 314530.0 -29400.0 -0.21 -1.0376 -0.8153 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O11 mock treatment 368000.0 -55500.0 -0.38 282720.0 -61200.0 -0.44 -0.5786 -0.9966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O12 mock treatment 408970.0 -14600.0 -0.1 328810.0 -15100.0 -0.11 -0.1469 -0.9986 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O13 compound treatment 418400.0 -5140.0 -0.03 286490.0 -57400.0 -0.42 -0.3185 -0.7635 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O14 compound treatment 401330.0 -22200.0 -0.15 398770.0 54900.0 0.4 0.1747 0.4115 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O15 compound treatment 359520.0 -64000.0 -0.43 286880.0 -57000.0 -0.41 -0.5978 -0.9997 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O16 compound treatment 315910.0 -108000.0 -0.73 277990.0 -65900.0 -0.48 -0.8517 -0.9791 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O17 compound treatment 319370.0 -104000.0 -0.7 265130.0 -78800.0 -0.57 -0.901 -0.9945 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O18 compound treatment 374420.0 -49100.0 -0.33 325850.0 -18100.0 -0.13 -0.3271 -0.9171 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O19 compound treatment 277600.0 -146000.0 -0.99 259840.0 -84100.0 -0.61 -1.1276 -0.9731 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O20 compound treatment 398560.0 -25000.0 -0.17 314490.0 -29400.0 -0.21 -0.2699 -0.9934 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O21 compound treatment 319630.0 -104000.0 -0.7 225280.0 -119000.0 -0.86 -1.1037 -0.995 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O22 compound treatment 334610.0 -88900.0 -0.6 324360.0 -19600.0 -0.14 -0.525 -0.8504 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O23 compound treatment 303250.0 -120000.0 -0.81 241300.0 -103000.0 -0.74 -1.1 -0.999 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 O24 compound treatment 278650.0 -145000.0 -0.98 223960.0 -120000.0 -0.87 -1.3062 -0.9982 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P01 compound treatment 203680.0 -220000.0 -1.49 197760.0 -146000.0 -1.06 -1.7985 -0.9862 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P02 compound treatment 277060.0 -146000.0 -0.99 155110.0 -189000.0 -1.37 -1.6663 -0.9874 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P03 compound treatment 246210.0 -177000.0 -1.2 162270.0 -182000.0 -1.31 -1.777 -0.9989 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P04 compound treatment 192860.0 -231000.0 -1.56 192100.0 -152000.0 -1.1 -1.8792 -0.9854 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P05 compound treatment 116230.0 -307000.0 -2.08 170830.0 -173000.0 -1.25 -2.3542 -0.9707 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P06 compound treatment 231310.0 -192000.0 -1.3 210030.0 -134000.0 -0.97 -1.6037 -0.9896 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P07 compound treatment 109120.0 -314000.0 -2.12 97560.0 -246000.0 -1.78 -2.7632 -0.9962 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P08 compound treatment 176890.0 -247000.0 -1.67 187680.0 -156000.0 -1.13 -1.9781 -0.9822 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P09 compound treatment 182680.0 -241000.0 -1.63 156320.0 -188000.0 -1.36 -2.111 -0.996 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P10 compound treatment 244350.0 -179000.0 -1.21 254720.0 -89200.0 -0.65 -1.3127 -0.9567 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P11 mock treatment 318360.0 -105000.0 -0.71 223630.0 -120000.0 -0.87 -1.1182 -0.9949 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P12 mock treatment 293410.0 -130000.0 -0.88 227090.0 -117000.0 -0.85 -1.2197 -0.9998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P13 compound treatment 109610.0 -314000.0 -2.12 90200.0 -254000.0 -1.84 -2.7986 -0.9974 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P14 compound treatment 164430.0 -259000.0 -1.75 174780.0 -169000.0 -1.22 -2.1037 -0.9847 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P15 compound treatment 207630.0 -216000.0 -1.46 190850.0 -153000.0 -1.11 -1.815 -0.9908 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P16 compound treatment 283260.0 -140000.0 -0.95 208360.0 -136000.0 -0.98 -1.3641 -0.9999 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P17 compound treatment 83150.0 -340000.0 -2.3 66510.0 -277000.0 -2.01 -3.0462 -0.9977 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P18 compound treatment 221440.0 -202000.0 -1.37 206580.0 -137000.0 -0.99 -1.6685 -0.9878 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P19 compound treatment 144800.0 -279000.0 -1.88 162770.0 -181000.0 -1.31 -2.259 -0.9843 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P20 compound treatment 255730.0 -168000.0 -1.13 203220.0 -141000.0 -1.02 -1.5219 -0.9986 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P21 compound treatment 167880.0 -256000.0 -1.73 154050.0 -190000.0 -1.37 -2.1933 -0.9936 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P22 compound treatment 219540.0 -204000.0 -1.38 257370.0 -86500.0 -0.63 -1.4176 -0.9363 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P23 compound treatment 139000.0 -285000.0 -1.92 123070.0 -221000.0 -1.6 -2.4899 -0.9958 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2282 P24 compound treatment 287860.0 -136000.0 -0.92 185650.0 -158000.0 -1.15 -1.4583 -0.9939 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A01 compound treatment 312330.0 -23000.0 -0.16 205000.0 -90100.0 -0.65 -0.571 -0.8516 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A02 compound treatment 295940.0 -39400.0 -0.27 221030.0 -74100.0 -0.54 -0.5673 -0.9477 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A03 compound treatment 335120.0 -185.0 0.0 208730.0 -86400.0 -0.63 -0.443 -0.7085 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A04 compound treatment 265800.0 -69500.0 -0.47 287900.0 -7210.0 -0.05 -0.369 -0.7809 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A05 compound treatment 393050.0 57700.0 0.39 204320.0 -90800.0 -0.66 -0.1888 -0.2471 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A06 compound treatment 277800.0 -57500.0 -0.39 218370.0 -76700.0 -0.56 -0.6676 -0.9847 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A07 compound treatment 340080.0 4780.0 0.03 266150.0 -29000.0 -0.21 -0.1254 -0.5913 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A08 compound treatment 230050.0 -105000.0 -0.71 295840.0 728.0 0.01 -0.4992 -0.7018 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A09 compound treatment 354050.0 18700.0 0.13 242670.0 -52400.0 -0.38 -0.1789 -0.447 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A10 compound treatment 320800.0 -14500.0 -0.1 251100.0 -44000.0 -0.32 -0.2946 -0.8838 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A11 compound treatment 348130.0 12800.0 0.09 264220.0 -30900.0 -0.22 -0.0968 -0.4038 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A12 compound treatment 352020.0 16700.0 0.11 261120.0 -34000.0 -0.25 -0.0941 -0.3477 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A13 mock treatment 311430.0 -23900.0 -0.16 240890.0 -54200.0 -0.39 -0.3916 -0.9228 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A14 mock treatment 364260.0 29000.0 0.2 241990.0 -53100.0 -0.38 -0.1336 -0.3096 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A15 compound treatment 264920.0 -70400.0 -0.48 231770.0 -63300.0 -0.46 -0.6605 -0.9998 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A16 compound treatment 299560.0 -35700.0 -0.24 237050.0 -58100.0 -0.42 -0.468 -0.9654 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A17 compound treatment 335900.0 595.0 0.0 283920.0 -11200.0 -0.08 -0.0544 -0.6712 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A18 compound treatment 355100.0 19800.0 0.13 255400.0 -39700.0 -0.29 -0.1087 -0.3428 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A19 compound treatment 337010.0 1710.0 0.01 334040.0 38900.0 0.28 0.2074 0.7354 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A20 compound treatment 360530.0 25200.0 0.17 314470.0 19400.0 0.14 0.2196 0.9953 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A21 compound treatment 310850.0 -24500.0 -0.17 342610.0 47500.0 0.34 0.1263 0.331 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A22 compound treatment 373600.0 38300.0 0.26 270850.0 -24300.0 -0.18 0.0588 0.188 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A23 compound treatment 255380.0 -79900.0 -0.54 264220.0 -30900.0 -0.22 -0.54 -0.9238 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 A24 compound treatment 238880.0 -96400.0 -0.65 275540.0 -19600.0 -0.14 -0.5609 -0.8412 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B01 compound treatment 206140.0 -129000.0 -0.87 313070.0 18000.0 0.13 -0.5252 -0.5952 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B02 compound treatment 393790.0 58500.0 0.4 329010.0 33900.0 0.25 0.4529 0.9737 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B03 compound treatment 194770.0 -141000.0 -0.95 282310.0 -12800.0 -0.09 -0.737 -0.7724 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B04 compound treatment 389160.0 53900.0 0.36 336160.0 41000.0 0.3 0.4674 0.9949 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B05 compound treatment 377880.0 42600.0 0.29 287520.0 -7590.0 -0.05 0.1646 0.5619 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B06 compound treatment 274460.0 -60800.0 -0.41 266560.0 -28600.0 -0.21 -0.4369 -0.9494 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B07 compound treatment 334240.0 -1070.0 -0.01 239880.0 -55200.0 -0.4 -0.2878 -0.7197 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B08 compound treatment 362720.0 27400.0 0.19 282690.0 -12400.0 -0.09 0.0674 0.3273 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B09 compound treatment 291540.0 -43800.0 -0.3 300670.0 5560.0 0.04 -0.1806 -0.6053 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B10 compound treatment 96540.0 -239000.0 -1.61 89300.0 -206000.0 -1.49 -2.1943 -0.9992 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B11 compound treatment 284590.0 -50700.0 -0.34 320450.0 25300.0 0.18 -0.1126 -0.2897 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B12 compound treatment 216650.0 -119000.0 -0.8 217800.0 -77300.0 -0.56 -0.9626 -0.9846 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B13 mock treatment 361280.0 26000.0 0.18 309790.0 14700.0 0.11 0.1992 0.9711 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B14 mock treatment 308920.0 -26400.0 -0.18 348900.0 53800.0 0.39 0.1493 0.3485 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B15 compound treatment 337730.0 2430.0 0.02 300530.0 5420.0 0.04 0.0393 0.925 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B16 compound treatment 88830.0 -246000.0 -1.67 83540.0 -212000.0 -1.53 -2.2606 -0.9991 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B17 compound treatment 351960.0 16700.0 0.11 268270.0 -26800.0 -0.19 -0.0578 -0.2575 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B18 compound treatment 95040.0 -240000.0 -1.62 88640.0 -206000.0 -1.49 -2.2048 -0.9991 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B19 compound treatment 345970.0 10700.0 0.07 325280.0 30200.0 0.22 0.2054 0.8931 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B20 compound treatment 107240.0 -228000.0 -1.54 104000.0 -191000.0 -1.38 -2.0679 -0.9986 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B21 compound treatment 364610.0 29300.0 0.2 325340.0 30200.0 0.22 0.2947 0.9988 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B22 compound treatment 119570.0 -216000.0 -1.46 108540.0 -187000.0 -1.35 -1.9857 -0.9993 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B23 compound treatment 331810.0 -3500.0 -0.02 302040.0 6930.0 0.05 0.0188 0.3385 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 B24 compound treatment 107170.0 -228000.0 -1.54 105350.0 -190000.0 -1.37 -2.0613 -0.9983 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C01 compound treatment 260760.0 -74500.0 -0.5 277170.0 -17900.0 -0.13 -0.448 -0.8613 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C02 compound treatment 378120.0 42800.0 0.29 306630.0 11500.0 0.08 0.2635 0.8753 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C03 compound treatment 324370.0 -10900.0 -0.07 227080.0 -68000.0 -0.49 -0.4005 -0.8042 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C04 compound treatment 238820.0 -96500.0 -0.65 303580.0 8470.0 0.06 -0.4176 -0.6378 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C05 compound treatment 236980.0 -98300.0 -0.66 336100.0 41000.0 0.3 -0.26 -0.3573 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C06 compound treatment 381130.0 45800.0 0.31 354020.0 58900.0 0.43 0.5205 0.9876 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C07 compound treatment 390900.0 55600.0 0.38 280740.0 -14400.0 -0.1 0.1921 0.4927 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C08 compound treatment 335490.0 185.0 0.0 265470.0 -29600.0 -0.21 -0.1508 -0.703 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C09 compound treatment 223200.0 -112000.0 -0.76 304120.0 9010.0 0.07 -0.4895 -0.6439 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C10 compound treatment 231270.0 -104000.0 -0.7 265250.0 -29900.0 -0.22 -0.6499 -0.8837 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C11 mock treatment 354920.0 19600.0 0.13 247150.0 -48000.0 -0.35 -0.1518 -0.4084 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C12 mock treatment 353660.0 18400.0 0.12 247610.0 -47500.0 -0.34 -0.1554 -0.4253 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C13 compound treatment 10720.0 -325000.0 -2.19 8680.0 -286000.0 -2.07 -3.017 -0.9996 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C14 compound treatment 325410.0 -9900.0 -0.07 253940.0 -41200.0 -0.3 -0.258 -0.8447 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C15 mock treatment 377340.0 42000.0 0.28 260540.0 -34600.0 -0.25 0.0239 0.0631 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C16 mock treatment 359700.0 24400.0 0.16 259330.0 -35800.0 -0.26 -0.0666 -0.2169 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C17 compound treatment 29460.0 -306000.0 -2.07 15460.0 -280000.0 -2.02 -2.8927 -0.9999 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C18 compound treatment 377710.0 42400.0 0.29 292850.0 -2260.0 -0.02 0.191 0.6656 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C19 compound treatment 258890.0 -76400.0 -0.52 236800.0 -58300.0 -0.42 -0.6636 -0.995 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C20 compound treatment 292280.0 -43000.0 -0.29 281920.0 -13200.0 -0.1 -0.2731 -0.8925 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C21 compound treatment 307520.0 -27800.0 -0.19 283380.0 -11700.0 -0.08 -0.1928 -0.9357 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C22 compound treatment 304230.0 -31100.0 -0.21 323590.0 28500.0 0.21 -0.0027 -0.0092 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C23 compound treatment 343040.0 7740.0 0.05 305210.0 10100.0 0.07 0.0886 0.9865 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 C24 compound treatment 265660.0 -69600.0 -0.47 307310.0 12200.0 0.09 -0.2703 -0.5646 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D01 compound treatment 245670.0 -89600.0 -0.61 278840.0 -16300.0 -0.12 -0.5115 -0.8291 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D02 compound treatment 39570.0 -296000.0 -2.0 56980.0 -238000.0 -1.72 -2.6319 -0.9973 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D03 compound treatment 211910.0 -123000.0 -0.83 287710.0 -7400.0 -0.05 -0.6274 -0.751 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D04 compound treatment 242880.0 -92400.0 -0.62 193820.0 -101000.0 -0.73 -0.9601 -0.9968 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D05 compound treatment 268330.0 -67000.0 -0.45 245320.0 -49800.0 -0.36 -0.5749 -0.9936 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D06 compound treatment 138080.0 -197000.0 -1.33 114300.0 -181000.0 -1.31 -1.8678 -1.0 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D07 compound treatment 339580.0 4280.0 0.03 341300.0 46200.0 0.33 0.2568 0.7653 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D08 compound treatment 284030.0 -51300.0 -0.35 263040.0 -32100.0 -0.23 -0.4091 -0.981 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D09 compound treatment 260040.0 -75300.0 -0.51 276560.0 -18600.0 -0.13 -0.4546 -0.8642 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D10 compound treatment 231360.0 -104000.0 -0.7 190600.0 -105000.0 -0.76 -1.0316 -0.9993 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D11 mock treatment 345660.0 10400.0 0.07 280110.0 -15000.0 -0.11 -0.0273 -0.2114 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D12 mock treatment 281530.0 -53800.0 -0.36 316920.0 21800.0 0.16 -0.1453 -0.3668 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D13 compound treatment 361340.0 26000.0 0.18 218440.0 -76700.0 -0.56 -0.2681 -0.4604 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D14 compound treatment 138880.0 -196000.0 -1.33 110930.0 -184000.0 -1.33 -1.8812 -1.0 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D15 mock treatment 353480.0 18200.0 0.12 310240.0 15100.0 0.11 0.1643 0.9984 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D16 mock treatment 295920.0 -39400.0 -0.27 269120.0 -26000.0 -0.19 -0.3212 -0.9856 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D17 compound treatment 330400.0 -4910.0 -0.03 319140.0 24000.0 0.17 0.0996 0.5623 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D18 compound treatment 238790.0 -96500.0 -0.65 205360.0 -89800.0 -0.65 -0.9205 -1.0 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D19 compound treatment 353920.0 18600.0 0.13 304810.0 9700.0 0.07 0.1386 0.9621 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D20 compound treatment 358840.0 23500.0 0.16 282140.0 -13000.0 -0.09 0.046 0.2493 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D21 compound treatment 306310.0 -29000.0 -0.2 254370.0 -40700.0 -0.29 -0.3471 -0.9803 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D22 compound treatment 279290.0 -56000.0 -0.38 276350.0 -18800.0 -0.14 -0.3637 -0.9044 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D23 compound treatment 263640.0 -71700.0 -0.48 249300.0 -45800.0 -0.33 -0.5769 -0.983 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 D24 compound treatment 10880.0 -324000.0 -2.19 9230.0 -286000.0 -2.07 -3.0134 -0.9996 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E01 mock treatment 348740.0 13400.0 0.09 313920.0 18800.0 0.14 0.1605 0.9806 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E02 mock treatment 334080.0 -1230.0 -0.01 280640.0 -14500.0 -0.1 -0.0799 -0.7606 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E03 compound treatment 407680.0 72400.0 0.49 342780.0 47700.0 0.35 0.5898 0.9854 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E04 compound treatment 254990.0 -80300.0 -0.54 286330.0 -8780.0 -0.06 -0.4287 -0.7846 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E05 compound treatment 368000.0 32700.0 0.22 369620.0 74500.0 0.54 0.5376 0.9224 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E06 compound treatment 241630.0 -93700.0 -0.63 322670.0 27600.0 0.2 -0.3065 -0.4618 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E07 compound treatment 377330.0 42000.0 0.28 307680.0 12600.0 0.09 0.2651 0.8891 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E08 compound treatment 240440.0 -94900.0 -0.64 270090.0 -25000.0 -0.18 -0.5813 -0.8727 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E09 mock treatment 329250.0 -6060.0 -0.04 348520.0 53400.0 0.39 0.2445 0.6288 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E10 mock treatment 421600.0 86300.0 0.58 319550.0 24400.0 0.18 0.5374 0.8819 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E11 compound treatment 363270.0 28000.0 0.19 218570.0 -76500.0 -0.55 -0.2582 -0.441 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E12 compound treatment 265860.0 -69400.0 -0.47 246260.0 -48900.0 -0.35 -0.5819 -0.9903 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E13 compound treatment 296640.0 -38700.0 -0.26 321550.0 26400.0 0.19 -0.0494 -0.1525 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E14 compound treatment 198830.0 -136000.0 -0.92 154690.0 -140000.0 -1.02 -1.3708 -0.9988 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E15 compound treatment 371900.0 36600.0 0.25 334400.0 39300.0 0.28 0.3759 0.9976 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E16 compound treatment 174880.0 -160000.0 -1.08 155870.0 -139000.0 -1.01 -1.4792 -0.9993 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E17 mock treatment 380420.0 45100.0 0.3 290360.0 -4750.0 -0.03 0.1912 0.6234 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E18 mock treatment 341760.0 6460.0 0.04 303690.0 8580.0 0.06 0.0748 0.9851 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E19 compound treatment 360960.0 25700.0 0.17 337250.0 42100.0 0.31 0.3383 0.9641 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E20 compound treatment 300550.0 -34800.0 -0.23 329810.0 34700.0 0.25 0.0116 0.0336 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E21 compound treatment 342240.0 6940.0 0.05 371760.0 76600.0 0.55 0.4255 0.7641 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E22 compound treatment 305000.0 -30300.0 -0.2 361980.0 66900.0 0.48 0.1975 0.3757 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E23 compound treatment 338400.0 3100.0 0.02 337280.0 42200.0 0.31 0.2306 0.7538 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 E24 compound treatment 306450.0 -28900.0 -0.19 237640.0 -57500.0 -0.42 -0.432 -0.9403 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F01 mock treatment 365480.0 30200.0 0.2 227630.0 -67500.0 -0.49 -0.2012 -0.3802 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F02 mock treatment 359010.0 23700.0 0.16 265940.0 -29200.0 -0.21 -0.0361 -0.1361 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F03 compound treatment 269530.0 -65800.0 -0.44 308410.0 13300.0 0.1 -0.2462 -0.5414 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F04 compound treatment 327710.0 -7600.0 -0.05 225770.0 -69300.0 -0.5 -0.3912 -0.7754 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F05 compound treatment 326080.0 -9230.0 -0.06 330600.0 35500.0 0.26 0.1376 0.5204 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F06 compound treatment 285670.0 -49600.0 -0.34 195460.0 -99700.0 -0.72 -0.7472 -0.9393 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F07 compound treatment 229800.0 -106000.0 -0.71 226140.0 -69000.0 -0.5 -0.8571 -0.9848 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F08 compound treatment 441960.0 107000.0 0.72 341800.0 46700.0 0.34 0.7486 0.9404 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F09 mock treatment 398320.0 63000.0 0.43 331300.0 36200.0 0.26 0.4863 0.9728 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F10 mock treatment 362310.0 27000.0 0.18 282600.0 -12500.0 -0.09 0.065 0.319 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F11 compound treatment 390400.0 55100.0 0.37 239100.0 -56000.0 -0.41 -0.0235 -0.0426 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F12 compound treatment 317300.0 -18000.0 -0.12 192170.0 -103000.0 -0.75 -0.613 -0.8118 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F13 compound treatment 384890.0 49600.0 0.34 308220.0 13100.0 0.09 0.304 0.873 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F14 compound treatment 354260.0 19000.0 0.13 317760.0 22600.0 0.16 0.2065 0.9925 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F15 compound treatment 354560.0 19300.0 0.13 318120.0 23000.0 0.17 0.2098 0.9925 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F16 compound treatment 154560.0 -181000.0 -1.22 122910.0 -172000.0 -1.25 -1.745 -0.9999 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F17 mock treatment 417600.0 82300.0 0.56 352160.0 57000.0 0.41 0.6852 0.9893 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F18 mock treatment 344360.0 9060.0 0.06 326560.0 31400.0 0.23 0.2042 0.8664 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F19 compound treatment 370820.0 35500.0 0.24 337680.0 42600.0 0.31 0.3876 0.9924 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F20 compound treatment 335220.0 -85.0 0.0 334450.0 39300.0 0.28 0.201 0.7057 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F21 compound treatment 286680.0 -48600.0 -0.33 293880.0 -1230.0 -0.01 -0.2386 -0.726 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F22 compound treatment 324670.0 -10600.0 -0.07 358560.0 63400.0 0.46 0.274 0.5893 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F23 compound treatment 354920.0 19600.0 0.13 344850.0 49700.0 0.36 0.3483 0.9078 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 F24 compound treatment 299730.0 -35600.0 -0.24 299900.0 4790.0 0.03 -0.1455 -0.5989 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G01 compound treatment 252730.0 -82600.0 -0.56 260490.0 -34600.0 -0.25 -0.5717 -0.9348 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G02 compound treatment 366100.0 30800.0 0.21 311360.0 16200.0 0.12 0.2303 0.9635 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G03 mock treatment 393610.0 58300.0 0.39 256440.0 -38700.0 -0.28 0.0806 0.1668 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G04 mock treatment 361120.0 25800.0 0.17 284990.0 -10100.0 -0.07 0.0715 0.3781 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G05 compound treatment 403160.0 67900.0 0.46 336130.0 41000.0 0.3 0.5342 0.9779 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G06 compound treatment 394630.0 59300.0 0.4 212640.0 -82500.0 -0.6 -0.1387 -0.1929 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G07 compound treatment 367410.0 32100.0 0.22 274440.0 -20700.0 -0.15 0.0476 0.1805 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G08 compound treatment 329600.0 -5710.0 -0.04 267170.0 -27900.0 -0.2 -0.1703 -0.827 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G09 compound treatment 388510.0 53200.0 0.36 339110.0 44000.0 0.32 0.4794 0.9982 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G10 compound treatment 367070.0 31800.0 0.21 324540.0 29400.0 0.21 0.3024 1.0 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G11 compound treatment 170000.0 -165000.0 -1.12 282720.0 -12400.0 -0.09 -0.8532 -0.7614 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G12 compound treatment 125030.0 -210000.0 -1.42 105640.0 -189000.0 -1.37 -1.9745 -0.9998 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G13 compound treatment 302080.0 -33200.0 -0.22 290190.0 -4920.0 -0.04 -0.1839 -0.8092 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G14 compound treatment 360380.0 25100.0 0.17 302910.0 7800.0 0.06 0.1597 0.8944 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G15 compound treatment 378350.0 43000.0 0.29 326590.0 31500.0 0.23 0.3668 0.9927 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G16 compound treatment 379050.0 43700.0 0.3 284240.0 -10900.0 -0.08 0.1534 0.5014 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G17 compound treatment 368110.0 32800.0 0.22 293830.0 -1280.0 -0.01 0.1502 0.6769 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G18 compound treatment 399450.0 64100.0 0.43 324160.0 29000.0 0.21 0.4552 0.9448 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G19 mock treatment 401450.0 66100.0 0.45 343070.0 48000.0 0.35 0.5615 0.9922 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G20 mock treatment 397920.0 62600.0 0.42 234960.0 -60200.0 -0.44 -0.0087 -0.0144 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G21 compound treatment 400530.0 65200.0 0.44 317660.0 22500.0 0.16 0.4271 0.9087 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G22 compound treatment 337540.0 2240.0 0.02 320250.0 25100.0 0.18 0.1394 0.7632 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G23 compound treatment 403390.0 68100.0 0.46 284900.0 -10200.0 -0.07 0.273 0.586 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 G24 compound treatment 270510.0 -64800.0 -0.44 301700.0 6590.0 0.05 -0.2759 -0.6264 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H01 compound treatment 366360.0 31100.0 0.21 294330.0 -782.0 -0.01 0.1444 0.6878 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H02 compound treatment 192800.0 -143000.0 -0.96 229710.0 -65400.0 -0.47 -1.0156 -0.9466 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H03 mock treatment 408970.0 73700.0 0.5 257870.0 -37200.0 -0.27 0.1613 0.285 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H04 mock treatment 389780.0 54500.0 0.37 298410.0 3300.0 0.02 0.2772 0.7514 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H05 compound treatment 267110.0 -68200.0 -0.46 257940.0 -37200.0 -0.27 -0.5161 -0.9672 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H06 compound treatment 212250.0 -123000.0 -0.83 178150.0 -117000.0 -0.85 -1.1866 -1.0 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H07 compound treatment 299840.0 -35500.0 -0.24 289440.0 -5670.0 -0.04 -0.1985 -0.8164 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H08 mock treatment 376570.0 41300.0 0.28 320640.0 25500.0 0.18 0.3278 0.98 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H09 compound treatment 312800.0 -22500.0 -0.15 283650.0 -11500.0 -0.08 -0.1662 -0.9594 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H10 mock treatment 390000.0 54700.0 0.37 255290.0 -39800.0 -0.29 0.0575 0.1227 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H11 compound treatment 251690.0 -83600.0 -0.56 316850.0 21700.0 0.16 -0.2882 -0.4914 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H12 mock treatment 255430.0 -79900.0 -0.54 277240.0 -17900.0 -0.13 -0.4731 -0.8525 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H13 compound treatment 353240.0 17900.0 0.12 262500.0 -32600.0 -0.24 -0.0812 -0.3061 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H14 mock treatment 332480.0 -2830.0 -0.02 323420.0 28300.0 0.2 0.1314 0.6385 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H15 compound treatment 330940.0 -4370.0 -0.03 354080.0 59000.0 0.43 0.281 0.6567 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H16 mock treatment 405830.0 70500.0 0.48 330080.0 35000.0 0.25 0.5159 0.9562 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H17 compound treatment 361780.0 26500.0 0.18 346760.0 51600.0 0.37 0.3909 0.943 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H18 mock treatment 345030.0 9730.0 0.07 365850.0 70700.0 0.51 0.4086 0.7914 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H19 mock treatment 380700.0 45400.0 0.31 348680.0 53600.0 0.39 0.4911 0.9933 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H20 mock treatment 452370.0 117000.0 0.79 316400.0 21300.0 0.15 0.6683 0.8293 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H21 compound treatment 362500.0 27200.0 0.18 328160.0 33000.0 0.24 0.2991 0.9915 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H22 mock treatment 364900.0 29600.0 0.2 296340.0 1230.0 0.01 0.1477 0.7378 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H23 compound treatment 297030.0 -38300.0 -0.26 355840.0 60700.0 0.44 0.128 0.2509 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 H24 mock treatment 258650.0 -76700.0 -0.52 288960.0 -6150.0 -0.04 -0.3977 -0.7651 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I01 compound treatment 315100.0 -20200.0 -0.14 256870.0 -38200.0 -0.28 -0.2923 -0.9469 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I02 compound treatment 227130.0 -108000.0 -0.73 296850.0 1740.0 0.01 -0.5079 -0.6948 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I03 compound treatment 62250.0 -273000.0 -1.84 156580.0 -139000.0 -1.0 -2.0137 -0.9589 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I04 compound treatment 201850.0 -133000.0 -0.9 199480.0 -95600.0 -0.69 -1.1271 -0.9915 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I05 mock treatment 384890.0 49600.0 0.34 251430.0 -43700.0 -0.32 0.0133 0.0289 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I06 mock treatment 275550.0 -59800.0 -0.4 308530.0 13400.0 0.1 -0.2168 -0.5221 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I07 compound treatment 340180.0 4880.0 0.03 310980.0 15900.0 0.11 0.1045 0.8746 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I08 compound treatment 147240.0 -188000.0 -1.27 139070.0 -156000.0 -1.13 -1.6973 -0.9983 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I09 compound treatment 232030.0 -103000.0 -0.7 369220.0 74100.0 0.54 -0.1141 -0.1296 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I10 compound treatment 158560.0 -177000.0 -1.19 151840.0 -143000.0 -1.04 -1.5778 -0.9975 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I11 compound treatment 374730.0 39400.0 0.27 317440.0 22300.0 0.16 0.3027 0.9713 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I12 compound treatment 200660.0 -135000.0 -0.91 193380.0 -102000.0 -0.74 -1.164 -0.9945 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I13 compound treatment 368090.0 32800.0 0.22 345790.0 50700.0 0.37 0.416 0.9708 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I14 compound treatment 277530.0 -57800.0 -0.39 198240.0 -96900.0 -0.7 -0.7719 -0.9618 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I15 compound treatment 361920.0 26600.0 0.18 207700.0 -87400.0 -0.63 -0.3203 -0.4869 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I16 compound treatment 117760.0 -218000.0 -1.47 98180.0 -197000.0 -1.43 -2.0474 -0.9999 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I17 compound treatment 372920.0 37600.0 0.25 263330.0 -31800.0 -0.23 0.017 0.0497 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I18 compound treatment 318510.0 -16800.0 -0.11 324130.0 29000.0 0.21 0.0683 0.286 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I19 compound treatment 369120.0 33800.0 0.23 333980.0 38900.0 0.28 0.3605 0.9947 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I20 compound treatment 302530.0 -32800.0 -0.22 240370.0 -54700.0 -0.4 -0.4368 -0.9622 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I21 mock treatment 329050.0 -6260.0 -0.04 360910.0 65800.0 0.48 0.3069 0.6418 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I22 mock treatment 343080.0 7780.0 0.05 330400.0 35300.0 0.26 0.2178 0.8351 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I23 compound treatment 229220.0 -106000.0 -0.72 204870.0 -90200.0 -0.65 -0.9688 -0.9989 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 I24 compound treatment 129700.0 -206000.0 -1.39 111370.0 -184000.0 -1.33 -1.9229 -0.9998 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J01 compound treatment 292090.0 -43200.0 -0.29 227150.0 -68000.0 -0.49 -0.5543 -0.969 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J02 mock treatment 293210.0 -42100.0 -0.28 238300.0 -56800.0 -0.41 -0.4919 -0.9838 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J03 compound treatment 262050.0 -73300.0 -0.49 239100.0 -56000.0 -0.41 -0.6367 -0.9951 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J04 mock treatment 340590.0 5290.0 0.04 218670.0 -76400.0 -0.55 -0.366 -0.6601 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J05 mock treatment 371730.0 36400.0 0.25 238020.0 -57100.0 -0.41 -0.1182 -0.2457 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J06 mock treatment 252880.0 -82400.0 -0.56 261390.0 -33700.0 -0.24 -0.5664 -0.9315 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J07 compound treatment 315250.0 -20100.0 -0.14 273800.0 -21300.0 -0.15 -0.2049 -0.9979 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J08 mock treatment 371840.0 36500.0 0.25 274080.0 -21000.0 -0.15 0.0669 0.2307 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J09 compound treatment 375150.0 39800.0 0.27 233710.0 -61400.0 -0.44 -0.1239 -0.2385 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J10 mock treatment 451490.0 116000.0 0.79 362670.0 67600.0 0.49 0.9009 0.9741 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J11 compound treatment 193170.0 -142000.0 -0.96 145820.0 -149000.0 -1.08 -1.4433 -0.9983 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J12 mock treatment 309600.0 -25700.0 -0.17 186570.0 -109000.0 -0.79 -0.6784 -0.8431 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J13 compound treatment 332700.0 -2610.0 -0.02 300450.0 5340.0 0.04 0.0149 0.3504 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J14 mock treatment 372920.0 37600.0 0.25 261660.0 -33500.0 -0.24 0.0085 0.0242 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J15 compound treatment 310720.0 -24600.0 -0.17 252840.0 -42300.0 -0.31 -0.3338 -0.9588 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J16 mock treatment 369400.0 34100.0 0.23 340840.0 45700.0 0.33 0.397 0.9843 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J17 compound treatment 314430.0 -20900.0 -0.14 283460.0 -11700.0 -0.08 -0.1594 -0.9698 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J18 mock treatment 340920.0 5620.0 0.04 314440.0 19300.0 0.14 0.1258 0.8675 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J19 compound treatment 316380.0 -18900.0 -0.13 274310.0 -20800.0 -0.15 -0.1969 -0.9967 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J20 mock treatment 282500.0 -52800.0 -0.36 347890.0 52800.0 0.38 0.0179 0.0342 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J21 mock treatment 255300.0 -80000.0 -0.54 300930.0 5820.0 0.04 -0.3525 -0.65 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J22 mock treatment 272910.0 -62400.0 -0.42 353480.0 58400.0 0.42 7.0E-4 0.0011 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J23 compound treatment 249870.0 -85400.0 -0.58 275910.0 -19200.0 -0.14 -0.5065 -0.853 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 J24 mock treatment 278730.0 -56600.0 -0.38 282240.0 -12900.0 -0.09 -0.3362 -0.8544 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K01 compound treatment 5480.0 -330000.0 -2.23 4400.0 -291000.0 -2.1 -3.0639 -0.9996 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K02 compound treatment 128500.0 -207000.0 -1.4 115570.0 -180000.0 -1.3 -1.9071 -0.9993 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K03 compound treatment 7250.0 -328000.0 -2.22 6920.0 -288000.0 -2.09 -3.0425 -0.9995 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K04 compound treatment 329180.0 -6130.0 -0.04 289850.0 -5260.0 -0.04 -0.0562 -0.9991 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K05 compound treatment 96710.0 -239000.0 -1.61 108490.0 -187000.0 -1.35 -2.0952 -0.9961 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K06 compound treatment 133930.0 -201000.0 -1.36 128840.0 -166000.0 -1.2 -1.8132 -0.9981 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K07 mock treatment 358340.0 23000.0 0.16 223890.0 -71200.0 -0.52 -0.2545 -0.4726 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K08 mock treatment 343140.0 7840.0 0.05 403370.0 108000.0 0.78 0.5916 0.7532 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K09 compound treatment 259720.0 -75600.0 -0.51 198310.0 -96800.0 -0.7 -0.8566 -0.9879 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K10 compound treatment 325510.0 -9800.0 -0.07 292070.0 -3040.0 -0.02 -0.0624 -0.8942 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K11 compound treatment 170150.0 -165000.0 -1.12 232760.0 -62400.0 -0.45 -1.1082 -0.9207 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K12 compound treatment 280490.0 -54800.0 -0.37 327480.0 32400.0 0.23 -0.0962 -0.2195 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K13 compound treatment 361350.0 26000.0 0.18 295470.0 358.0 0.0 0.1263 0.7175 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K14 compound treatment 298580.0 -36700.0 -0.25 372320.0 77200.0 0.56 0.2197 0.3593 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K15 mock treatment 454080.0 119000.0 0.8 309760.0 14600.0 0.11 0.6425 0.7936 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K16 mock treatment 426420.0 91100.0 0.62 357300.0 62200.0 0.45 0.7537 0.9882 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K17 compound treatment 398560.0 63300.0 0.43 413970.0 119000.0 0.86 0.9106 0.9479 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K18 compound treatment 452020.0 117000.0 0.79 365390.0 70300.0 0.51 0.9174 0.9775 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K19 compound treatment 329920.0 -5390.0 -0.04 287170.0 -7940.0 -0.06 -0.0664 -0.9757 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K20 compound treatment 288530.0 -46800.0 -0.32 287640.0 -7470.0 -0.05 -0.2617 -0.8162 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K21 compound treatment 264020.0 -71300.0 -0.48 319010.0 23900.0 0.17 -0.2183 -0.4265 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K22 compound treatment 353010.0 17700.0 0.12 345510.0 50400.0 0.36 0.3426 0.8922 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K23 mock treatment 332650.0 -2660.0 -0.02 419750.0 125000.0 0.9 0.6253 0.6929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 K24 mock treatment 252890.0 -82400.0 -0.56 330680.0 35600.0 0.26 -0.2117 -0.3451 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L01 compound treatment 350110.0 14800.0 0.1 331360.0 36200.0 0.26 0.2563 0.9126 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L02 mock treatment 255590.0 -79700.0 -0.54 293810.0 -1300.0 -0.01 -0.3875 -0.7194 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L03 compound treatment 364500.0 29200.0 0.2 311870.0 16800.0 0.12 0.2253 0.9727 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L04 mock treatment 425160.0 89900.0 0.61 245490.0 -49600.0 -0.36 0.1753 0.2485 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L05 compound treatment 224870.0 -110000.0 -0.75 398130.0 103000.0 0.75 -3.0E-4 -3.0E-4 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L06 mock treatment 341560.0 6260.0 0.04 347440.0 52300.0 0.38 0.2977 0.7812 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L07 mock treatment 329250.0 -6060.0 -0.04 185500.0 -110000.0 -0.79 -0.59 -0.7426 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L08 mock treatment 335930.0 625.0 0.0 276880.0 -18200.0 -0.13 -0.0903 -0.6841 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L09 compound treatment 406660.0 71400.0 0.48 264640.0 -30500.0 -0.22 0.1849 0.3488 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L10 mock treatment 379950.0 44600.0 0.3 313290.0 18200.0 0.13 0.3064 0.9309 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L11 compound treatment 385330.0 50000.0 0.34 250570.0 -44500.0 -0.32 0.011 0.0236 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L12 mock treatment 332070.0 -3240.0 -0.02 416890.0 122000.0 0.88 0.6079 0.6894 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L13 compound treatment 472330.0 137000.0 0.93 383780.0 88700.0 0.64 1.1085 0.984 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L14 mock treatment 305850.0 -29500.0 -0.2 349190.0 54100.0 0.39 0.1361 0.3099 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L15 mock treatment 313600.0 -21700.0 -0.15 291920.0 -3190.0 -0.02 -0.12 -0.8085 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L16 mock treatment 371960.0 36700.0 0.25 333120.0 38000.0 0.28 0.3697 0.9986 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L17 compound treatment 372740.0 37400.0 0.25 287200.0 -7910.0 -0.06 0.1384 0.5335 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L18 mock treatment 399390.0 64100.0 0.43 396160.0 101000.0 0.73 0.8234 0.9687 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L19 compound treatment 346450.0 11100.0 0.08 335170.0 40100.0 0.29 0.2583 0.8621 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L20 mock treatment 336420.0 1120.0 0.01 251580.0 -43500.0 -0.32 -0.2175 -0.69 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L21 compound treatment 290840.0 -44500.0 -0.3 313830.0 18700.0 0.14 -0.1166 -0.3539 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L22 mock treatment 361610.0 26300.0 0.18 434570.0 139000.0 1.01 0.8395 0.819 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L23 mock treatment 347880.0 12600.0 0.08 278400.0 -16700.0 -0.12 -0.0255 -0.1722 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 L24 mock treatment 396740.0 61400.0 0.42 374630.0 79500.0 0.58 0.7006 0.9871 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M01 compound treatment 7370.0 -328000.0 -2.22 4380.0 -291000.0 -2.1 -3.055 -0.9997 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M02 compound treatment 356200.0 20900.0 0.14 178570.0 -117000.0 -0.84 -0.4967 -0.5807 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M03 compound treatment 208650.0 -127000.0 -0.86 165380.0 -130000.0 -0.94 -1.2692 -0.9989 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M04 compound treatment 299440.0 -35900.0 -0.24 361960.0 66800.0 0.48 0.1708 0.3156 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M05 compound treatment 12560.0 -323000.0 -2.18 8850.0 -286000.0 -2.07 -3.0073 -0.9997 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M06 compound treatment 396440.0 61100.0 0.41 233030.0 -62100.0 -0.45 -0.0257 -0.0421 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M07 compound treatment 231300.0 -104000.0 -0.7 262790.0 -32300.0 -0.23 -0.6624 -0.8943 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M08 compound treatment 321760.0 -13500.0 -0.09 322680.0 27600.0 0.2 0.0764 0.348 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M09 mock treatment 387690.0 52400.0 0.35 277470.0 -17600.0 -0.13 0.16 0.4252 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M10 mock treatment 441050.0 106000.0 0.71 418850.0 124000.0 0.9 1.1386 0.9937 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M11 compound treatment 421820.0 86500.0 0.58 277120.0 -18000.0 -0.13 0.3213 0.5364 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M12 compound treatment 276340.0 -59000.0 -0.4 349330.0 54200.0 0.39 -0.0042 -0.0075 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M13 mock treatment 403060.0 67800.0 0.46 353230.0 58100.0 0.42 0.6212 0.9991 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M14 mock treatment 368840.0 33500.0 0.23 263360.0 -31800.0 -0.23 -0.0023 -0.0071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M15 compound treatment 309200.0 -26100.0 -0.18 252750.0 -42400.0 -0.31 -0.3416 -0.9655 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M16 compound treatment 364020.0 28700.0 0.19 316640.0 21500.0 0.16 0.2474 0.9941 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M17 compound treatment 327380.0 -7930.0 -0.05 302130.0 7020.0 0.05 -0.0019 -0.0263 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M18 compound treatment 290430.0 -44900.0 -0.3 239410.0 -55700.0 -0.4 -0.4995 -0.9901 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M19 compound treatment 397930.0 62600.0 0.42 292880.0 -2230.0 -0.02 0.2878 0.6796 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M20 compound treatment 265770.0 -69500.0 -0.47 384830.0 89700.0 0.65 0.127 0.1585 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M21 compound treatment 367800.0 32500.0 0.22 181200.0 -114000.0 -0.82 -0.4278 -0.5014 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M22 compound treatment 272160.0 -63100.0 -0.43 204330.0 -90800.0 -0.66 -0.7664 -0.9781 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M23 compound treatment 389810.0 54500.0 0.37 384100.0 89000.0 0.64 0.7159 0.9648 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 M24 compound treatment 163420.0 -172000.0 -1.16 215160.0 -80000.0 -0.58 -1.2305 -0.9483 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N01 compound treatment 206520.0 -129000.0 -0.87 248240.0 -46900.0 -0.34 -0.8552 -0.9157 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N02 mock treatment 329780.0 -5530.0 -0.04 249760.0 -45400.0 -0.33 -0.2585 -0.7825 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N03 compound treatment 301490.0 -33800.0 -0.23 341990.0 46900.0 0.34 0.0784 0.1916 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N04 mock treatment 325440.0 -9870.0 -0.07 234960.0 -60200.0 -0.44 -0.355 -0.806 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N05 compound treatment 446320.0 111000.0 0.75 203300.0 -91800.0 -0.66 0.0605 0.0603 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N06 mock treatment 200580.0 -135000.0 -0.91 281980.0 -13100.0 -0.1 -0.7109 -0.7767 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N07 compound treatment 385810.0 50500.0 0.34 287220.0 -7890.0 -0.06 0.2009 0.5807 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N08 mock treatment 429090.0 93800.0 0.63 332490.0 37400.0 0.27 0.6394 0.928 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N09 mock treatment 458460.0 123000.0 0.83 380600.0 85500.0 0.62 1.026 0.9894 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N10 mock treatment 391770.0 56500.0 0.38 302680.0 7570.0 0.05 0.3085 0.8004 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N11 compound treatment 421960.0 86700.0 0.59 290250.0 -4860.0 -0.04 0.3891 0.6634 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N12 mock treatment 317120.0 -18200.0 -0.12 287330.0 -7780.0 -0.06 -0.1267 -0.9375 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N13 mock treatment 357600.0 22300.0 0.15 281760.0 -13400.0 -0.1 0.0382 0.2133 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N14 mock treatment 348240.0 12900.0 0.09 303790.0 8680.0 0.06 0.1062 0.9869 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N15 compound treatment 318090.0 -17200.0 -0.12 287220.0 -7890.0 -0.06 -0.1226 -0.9464 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N16 mock treatment 463060.0 128000.0 0.86 294630.0 -482.0 0.0 0.6079 0.7042 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N17 compound treatment 364990.0 29700.0 0.2 270290.0 -24800.0 -0.18 0.0148 0.0549 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N18 mock treatment 249980.0 -85300.0 -0.58 366050.0 70900.0 0.51 -0.0446 -0.0577 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N19 compound treatment 276930.0 -58400.0 -0.39 209560.0 -85600.0 -0.62 -0.7168 -0.9763 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N20 mock treatment 280980.0 -54300.0 -0.37 353870.0 58800.0 0.43 0.0412 0.0734 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N21 compound treatment 208000.0 -127000.0 -0.86 191230.0 -104000.0 -0.75 -1.14 -0.9978 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N22 mock treatment 260970.0 -74300.0 -0.5 375700.0 80600.0 0.58 0.0573 0.0745 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N23 compound treatment 298050.0 -37300.0 -0.25 232850.0 -62300.0 -0.45 -0.4967 -0.9621 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 N24 mock treatment 266330.0 -69000.0 -0.47 353360.0 58200.0 0.42 -0.0314 -0.0499 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O01 compound treatment 141320.0 -194000.0 -1.31 152650.0 -142000.0 -1.03 -1.656 -0.993 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O02 compound treatment 149970.0 -185000.0 -1.25 222620.0 -72500.0 -0.52 -1.2566 -0.9254 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O03 compound treatment 389080.0 53800.0 0.36 175370.0 -120000.0 -0.87 -0.356 -0.3788 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O04 compound treatment 176830.0 -158000.0 -1.07 204480.0 -90600.0 -0.66 -1.2211 -0.9724 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O05 compound treatment 174500.0 -161000.0 -1.09 166600.0 -129000.0 -0.93 -1.4261 -0.997 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O06 compound treatment 189940.0 -145000.0 -0.98 181190.0 -114000.0 -0.82 -1.2777 -0.9962 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O07 compound treatment 387200.0 51900.0 0.35 267920.0 -27200.0 -0.2 0.1088 0.2705 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O08 compound treatment 252250.0 -83100.0 -0.56 188120.0 -107000.0 -0.77 -0.9445 -0.9875 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O09 compound treatment 327250.0 -8060.0 -0.05 314400.0 19300.0 0.14 0.0602 0.402 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O10 compound treatment 321180.0 -14100.0 -0.1 310640.0 15500.0 0.11 0.012 0.0814 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O11 mock treatment 318440.0 -16900.0 -0.11 260590.0 -34500.0 -0.25 -0.2573 -0.9368 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O12 mock treatment 343580.0 8280.0 0.06 345410.0 50300.0 0.36 0.297 0.8062 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O13 compound treatment 234660.0 -101000.0 -0.68 312430.0 17300.0 0.13 -0.3922 -0.5672 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O14 compound treatment 298560.0 -36700.0 -0.25 244700.0 -50400.0 -0.36 -0.4336 -0.9824 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O15 compound treatment 270580.0 -64700.0 -0.44 315960.0 20800.0 0.15 -0.2025 -0.4378 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O16 compound treatment 345600.0 10300.0 0.07 349880.0 54800.0 0.4 0.3295 0.8187 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O17 compound treatment 298280.0 -37000.0 -0.25 376800.0 81700.0 0.59 0.2412 0.3757 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O18 compound treatment 335930.0 625.0 0.0 356640.0 61500.0 0.45 0.3179 0.7138 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O19 compound treatment 306310.0 -29000.0 -0.2 309390.0 14300.0 0.1 -0.0654 -0.2955 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O20 compound treatment 250880.0 -84400.0 -0.57 304400.0 9290.0 0.07 -0.3558 -0.6195 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O21 compound treatment 314000.0 -21300.0 -0.14 294470.0 -642.0 0.0 -0.1051 -0.7295 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O22 compound treatment 274430.0 -60900.0 -0.41 244190.0 -50900.0 -0.37 -0.5515 -0.9985 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O23 compound treatment 260050.0 -75300.0 -0.51 304910.0 9800.0 0.07 -0.3094 -0.6026 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 O24 compound treatment 199760.0 -136000.0 -0.92 223780.0 -71300.0 -0.52 -1.0127 -0.9632 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P01 compound treatment 160750.0 -175000.0 -1.18 124800.0 -170000.0 -1.23 -1.7058 -0.9998 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P02 mock treatment 265650.0 -69700.0 -0.47 220190.0 -74900.0 -0.54 -0.7163 -0.9975 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P03 compound treatment 197300.0 -138000.0 -0.93 190520.0 -105000.0 -0.76 -1.1947 -0.9947 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P04 mock treatment 259850.0 -75500.0 -0.51 222890.0 -72200.0 -0.52 -0.7302 -0.9999 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P05 compound treatment 301970.0 -33300.0 -0.23 241920.0 -53200.0 -0.39 -0.4315 -0.9674 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P06 mock treatment 206570.0 -129000.0 -0.87 206260.0 -88900.0 -0.64 -1.0699 -0.989 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P07 compound treatment 199080.0 -136000.0 -0.92 233630.0 -61500.0 -0.45 -0.9656 -0.9444 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P08 mock treatment 205820.0 -129000.0 -0.87 277310.0 -17800.0 -0.13 -0.7098 -0.8026 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P09 compound treatment 242630.0 -92700.0 -0.63 171600.0 -124000.0 -0.89 -1.075 -0.9848 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P10 mock treatment 219200.0 -116000.0 -0.78 244880.0 -50200.0 -0.36 -0.8118 -0.9389 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P11 mock treatment 155690.0 -180000.0 -1.21 202080.0 -93000.0 -0.67 -1.3344 -0.9614 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P12 mock treatment 255920.0 -79400.0 -0.54 227700.0 -67400.0 -0.49 -0.7243 -0.9989 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P13 compound treatment 140330.0 -195000.0 -1.32 198690.0 -96400.0 -0.7 -1.4251 -0.9559 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P14 mock treatment 240680.0 -94600.0 -0.64 172670.0 -122000.0 -0.89 -1.0788 -0.9871 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P15 compound treatment 231360.0 -104000.0 -0.7 250920.0 -44200.0 -0.32 -0.7228 -0.9366 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P16 mock treatment 251090.0 -84200.0 -0.57 219760.0 -75400.0 -0.55 -0.7881 -0.9998 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P17 compound treatment 162360.0 -173000.0 -1.17 150940.0 -144000.0 -1.04 -1.5643 -0.9984 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P18 mock treatment 266240.0 -69100.0 -0.47 253300.0 -41800.0 -0.3 -0.544 -0.978 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P19 compound treatment 223550.0 -112000.0 -0.76 198750.0 -96400.0 -0.7 -1.0272 -0.9992 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P20 mock treatment 213960.0 -121000.0 -0.82 225530.0 -69600.0 -0.5 -0.9359 -0.9726 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P21 compound treatment 220280.0 -115000.0 -0.78 208560.0 -86600.0 -0.63 -0.9926 -0.9943 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P22 mock treatment 212520.0 -123000.0 -0.83 225780.0 -69300.0 -0.5 -0.9415 -0.971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P23 compound treatment 173120.0 -162000.0 -1.1 206960.0 -88200.0 -0.64 -1.2261 -0.9669 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2283 P24 mock treatment 176000.0 -159000.0 -1.08 196110.0 -99000.0 -0.72 -1.2679 -0.9805 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A01 mock treatment 320080.0 -49700.0 -0.34 413500.0 33200.0 0.24 -0.0672 -0.1627 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A02 compound treatment 365220.0 -4540.0 -0.03 306770.0 -73500.0 -0.53 -0.3978 -0.7466 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A03 mock treatment 434770.0 65000.0 0.44 322000.0 -58300.0 -0.42 0.0124 0.0204 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A04 compound treatment 368740.0 -1020.0 -0.01 336160.0 -44100.0 -0.32 -0.2306 -0.7222 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A05 compound treatment 310190.0 -59600.0 -0.4 274560.0 -106000.0 -0.77 -0.8256 -0.955 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A06 compound treatment 184280.0 -185000.0 -1.25 224040.0 -156000.0 -1.13 -1.6858 -0.9987 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A07 mock treatment 375840.0 6080.0 0.04 330610.0 -49600.0 -0.36 -0.2251 -0.6222 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A08 compound treatment 374470.0 4710.0 0.03 399170.0 18900.0 0.14 0.1193 0.8489 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A09 compound treatment 402610.0 32900.0 0.22 405330.0 25100.0 0.18 0.2853 0.995 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A10 compound treatment 333810.0 -35900.0 -0.24 355640.0 -24600.0 -0.18 -0.2978 -0.9884 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A11 mock treatment 406080.0 36300.0 0.25 414130.0 33900.0 0.25 0.3469 1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A12 compound treatment 322960.0 -46800.0 -0.32 361370.0 -18900.0 -0.14 -0.3203 -0.9297 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A13 mock treatment 393710.0 24000.0 0.16 370080.0 -10200.0 -0.07 0.0623 0.3506 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A14 mock treatment 321350.0 -48400.0 -0.33 305540.0 -74700.0 -0.54 -0.6137 -0.971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A15 compound treatment 305680.0 -64100.0 -0.43 303950.0 -76300.0 -0.55 -0.6967 -0.9927 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A16 compound treatment 337850.0 -31900.0 -0.22 326890.0 -53400.0 -0.39 -0.4256 -0.962 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A17 compound treatment 140550.0 -229000.0 -1.55 142970.0 -237000.0 -1.72 -2.3097 -0.9987 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A18 compound treatment 10690.0 -359000.0 -2.43 17690.0 -363000.0 -2.62 -3.5714 -0.9992 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A19 compound treatment 309250.0 -60500.0 -0.41 308450.0 -71800.0 -0.52 -0.6566 -0.9929 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A20 compound treatment 371770.0 2010.0 0.01 268200.0 -112000.0 -0.81 -0.564 -0.6952 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A21 compound treatment 343200.0 -26600.0 -0.18 282030.0 -98200.0 -0.71 -0.6297 -0.8586 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A22 compound treatment 362640.0 -7120.0 -0.05 301120.0 -79100.0 -0.57 -0.4391 -0.7638 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A23 compound treatment 227410.0 -142000.0 -0.96 336430.0 -43800.0 -0.32 -0.9044 -0.893 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 A24 compound treatment 171840.0 -198000.0 -1.34 353120.0 -27100.0 -0.2 -1.0845 -0.8024 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B01 compound treatment 549320.0 180000.0 1.21 349340.0 -30900.0 -0.22 0.6997 0.5671 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B02 compound treatment 195040.0 -175000.0 -1.18 181290.0 -199000.0 -1.44 -1.8532 -0.9951 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B03 compound treatment 277220.0 -92500.0 -0.63 450960.0 70700.0 0.51 -0.0802 -0.0993 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B04 compound treatment 343800.0 -26000.0 -0.18 451070.0 70800.0 0.51 0.2385 0.4401 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B05 compound treatment 329890.0 -39900.0 -0.27 411530.0 31300.0 0.23 -0.0304 -0.0864 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B06 compound treatment 319300.0 -50500.0 -0.34 431680.0 51400.0 0.37 0.0221 0.0439 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B07 compound treatment 313540.0 -56200.0 -0.38 290460.0 -89800.0 -0.65 -0.7282 -0.9673 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B08 compound treatment 377000.0 7240.0 0.05 338440.0 -41800.0 -0.3 -0.1794 -0.5852 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B09 compound treatment 291230.0 -78500.0 -0.53 313660.0 -66600.0 -0.48 -0.7161 -0.9989 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B10 compound treatment 428900.0 59100.0 0.4 500130.0 120000.0 0.87 0.8962 0.9381 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B11 compound treatment 343840.0 -25900.0 -0.18 381840.0 1580.0 0.01 -0.1157 -0.6594 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B12 compound treatment 378830.0 9070.0 0.06 343360.0 -36900.0 -0.27 -0.1455 -0.531 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B13 mock treatment 411940.0 42200.0 0.29 297820.0 -82400.0 -0.6 -0.2204 -0.3333 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B14 mock treatment 389950.0 20200.0 0.14 361330.0 -18900.0 -0.14 -4.0E-4 -0.0021 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B15 compound treatment 309980.0 -59800.0 -0.4 289610.0 -90600.0 -0.66 -0.7496 -0.9728 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B16 compound treatment 245150.0 -125000.0 -0.84 314990.0 -65300.0 -0.47 -0.9294 -0.9627 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B17 compound treatment 178100.0 -192000.0 -1.29 204050.0 -176000.0 -1.28 -1.8177 -1.0 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B18 compound treatment 274980.0 -94800.0 -0.64 284100.0 -96200.0 -0.7 -0.945 -0.9991 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B19 compound treatment 375440.0 5680.0 0.04 317780.0 -62500.0 -0.45 -0.2926 -0.6448 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B20 mock treatment 337940.0 -31800.0 -0.21 330940.0 -49300.0 -0.36 -0.4045 -0.9705 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B21 compound treatment 314090.0 -55700.0 -0.38 276510.0 -104000.0 -0.75 -0.797 -0.9489 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B22 compound treatment 290760.0 -79000.0 -0.53 370590.0 -9670.0 -0.07 -0.4269 -0.793 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B23 compound treatment 273570.0 -96200.0 -0.65 254510.0 -126000.0 -0.91 -1.1032 -0.9864 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 B24 compound treatment 267330.0 -102000.0 -0.69 421640.0 41400.0 0.3 -0.2776 -0.368 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C01 compound treatment 396720.0 27000.0 0.18 415970.0 35700.0 0.26 0.3116 0.9853 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C02 compound treatment 362800.0 -6960.0 -0.05 410720.0 30500.0 0.22 0.1227 0.5441 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C03 compound treatment 306830.0 -62900.0 -0.43 471840.0 91600.0 0.66 0.1681 0.2135 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C04 compound treatment 305280.0 -64500.0 -0.44 406000.0 25700.0 0.19 -0.1763 -0.372 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C05 compound treatment 183720.0 -186000.0 -1.26 218770.0 -161000.0 -1.17 -1.7155 -0.9993 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C06 compound treatment 251690.0 -118000.0 -0.8 305520.0 -74700.0 -0.54 -0.9467 -0.9821 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C07 compound treatment 306050.0 -63700.0 -0.43 330570.0 -49700.0 -0.36 -0.5587 -0.996 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C08 compound treatment 327680.0 -42100.0 -0.28 386300.0 6040.0 0.04 -0.1701 -0.5913 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C09 compound treatment 410180.0 40400.0 0.27 327290.0 -53000.0 -0.38 -0.078 -0.1657 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C10 compound treatment 340440.0 -29300.0 -0.2 440580.0 60300.0 0.44 0.1687 0.3518 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C11 mock treatment 399090.0 29300.0 0.2 421120.0 40900.0 0.3 0.3493 0.981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C12 mock treatment 334260.0 -35500.0 -0.24 387780.0 7520.0 0.05 -0.1311 -0.533 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C13 compound treatment 397930.0 28200.0 0.19 402670.0 22400.0 0.16 0.2493 0.9968 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C14 compound treatment 385600.0 15800.0 0.11 382640.0 2380.0 0.02 0.0879 0.8106 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C15 mock treatment 323680.0 -46100.0 -0.31 336440.0 -43800.0 -0.32 -0.4444 -1.0 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C16 mock treatment 330960.0 -38800.0 -0.26 337150.0 -43100.0 -0.31 -0.406 -0.9962 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C17 compound treatment 204680.0 -165000.0 -1.12 200830.0 -179000.0 -1.3 -1.7071 -0.9971 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C18 compound treatment 310690.0 -59100.0 -0.4 296810.0 -83400.0 -0.6 -0.7094 -0.9798 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C19 compound treatment 298430.0 -71300.0 -0.48 320990.0 -59300.0 -0.43 -0.6442 -0.9983 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C20 compound treatment 220530.0 -149000.0 -1.01 167280.0 -213000.0 -1.54 -1.8031 -0.9788 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C21 compound treatment 39690.0 -330000.0 -2.23 36060.0 -344000.0 -2.49 -3.3388 -0.9985 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C22 compound treatment 335310.0 -34400.0 -0.23 339250.0 -41000.0 -0.3 -0.3745 -0.9928 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C23 compound treatment 258290.0 -111000.0 -0.75 354460.0 -25800.0 -0.19 -0.6646 -0.8565 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 C24 compound treatment 291200.0 -78600.0 -0.53 311200.0 -69100.0 -0.5 -0.7288 -0.9996 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D01 compound treatment 311840.0 -57900.0 -0.39 465390.0 85100.0 0.62 0.1591 0.2179 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D02 compound treatment 262080.0 -108000.0 -0.73 309890.0 -70400.0 -0.51 -0.8746 -0.9848 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D03 compound treatment 346080.0 -23700.0 -0.16 255490.0 -125000.0 -0.9 -0.7518 -0.8196 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D04 mock treatment 418420.0 48700.0 0.33 291120.0 -89100.0 -0.65 -0.2238 -0.309 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D05 compound treatment 421920.0 52200.0 0.35 383560.0 3300.0 0.02 0.2661 0.7533 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D06 compound treatment 342290.0 -27500.0 -0.19 408160.0 27900.0 0.2 0.0116 0.0423 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D07 compound treatment 327740.0 -42000.0 -0.28 277610.0 -103000.0 -0.74 -0.7262 -0.9129 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D08 mock treatment 380690.0 10900.0 0.07 330630.0 -49600.0 -0.36 -0.2018 -0.5502 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D09 compound treatment 439070.0 69300.0 0.47 439870.0 59600.0 0.43 0.6363 0.9992 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D10 compound treatment 291430.0 -78300.0 -0.53 253600.0 -127000.0 -0.92 -1.0226 -0.9659 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D11 mock treatment 410040.0 40300.0 0.27 392060.0 11800.0 0.09 0.2529 0.8864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D12 mock treatment 416340.0 46600.0 0.31 431070.0 50800.0 0.37 0.4827 0.997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D13 mock treatment 371360.0 1600.0 0.01 401610.0 21400.0 0.15 0.117 0.7548 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D14 compound treatment 330770.0 -39000.0 -0.26 322400.0 -57900.0 -0.42 -0.4824 -0.975 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D15 mock treatment 393860.0 24100.0 0.16 369180.0 -11100.0 -0.08 0.0585 0.322 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D16 mock treatment 281700.0 -88100.0 -0.59 422260.0 42000.0 0.3 -0.2057 -0.3079 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D17 compound treatment 362400.0 -7360.0 -0.05 385610.0 5350.0 0.04 -0.0078 -0.123 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D18 compound treatment 270280.0 -99500.0 -0.67 297920.0 -82300.0 -0.6 -0.8967 -0.9982 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D19 compound treatment 8260.0 -361000.0 -2.44 9470.0 -371000.0 -2.68 -3.6251 -0.9989 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D20 compound treatment 344820.0 -24900.0 -0.17 418560.0 38300.0 0.28 0.0769 0.2371 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D21 compound treatment 273640.0 -96100.0 -0.65 412040.0 31800.0 0.23 -0.2965 -0.4304 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D22 compound treatment 375730.0 5970.0 0.04 315950.0 -64300.0 -0.47 -0.3006 -0.6434 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D23 mock treatment 287900.0 -81900.0 -0.55 449350.0 69100.0 0.5 -0.0374 -0.0502 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 D24 compound treatment 262330.0 -107000.0 -0.73 400750.0 20500.0 0.15 -0.4084 -0.5512 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E01 mock treatment 431920.0 62200.0 0.42 304890.0 -75400.0 -0.55 -0.0888 -0.1289 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E02 mock treatment 417330.0 47600.0 0.32 353930.0 -26300.0 -0.19 0.0925 0.2476 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E03 mock treatment 390690.0 20900.0 0.14 387370.0 7110.0 0.05 0.1364 0.9063 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E04 compound treatment 340970.0 -28800.0 -0.19 353280.0 -27000.0 -0.2 -0.2756 -1.0 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E05 compound treatment 163380.0 -206000.0 -1.39 258430.0 -122000.0 -0.88 -1.6096 -0.9756 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E06 compound treatment 273680.0 -96100.0 -0.65 307320.0 -72900.0 -0.53 -0.8324 -0.9947 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E07 compound treatment 343450.0 -26300.0 -0.18 354500.0 -25800.0 -0.19 -0.2575 -0.9997 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E08 compound treatment 401240.0 31500.0 0.21 420210.0 40000.0 0.29 0.3549 0.9886 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E09 mock treatment 458630.0 88900.0 0.6 417970.0 37700.0 0.27 0.6177 0.9364 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E10 mock treatment 471090.0 101000.0 0.68 394610.0 14400.0 0.1 0.5576 0.8052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E11 compound treatment 260970.0 -109000.0 -0.74 192130.0 -188000.0 -1.36 -1.4827 -0.9581 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E12 compound treatment 348610.0 -21100.0 -0.14 369440.0 -10800.0 -0.08 -0.1564 -0.9599 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E13 compound treatment 388030.0 18300.0 0.12 376290.0 -3970.0 -0.03 0.067 0.5285 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E14 compound treatment 402080.0 32300.0 0.22 407680.0 27400.0 0.2 0.2948 0.9989 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E15 compound treatment 228960.0 -141000.0 -0.95 246690.0 -134000.0 -0.97 -1.3564 -1.0 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E16 compound treatment 296420.0 -73300.0 -0.5 286880.0 -93400.0 -0.68 -0.8284 -0.9883 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E17 mock treatment 414910.0 45200.0 0.31 324810.0 -55400.0 -0.4 -0.0681 -0.135 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E18 mock treatment 337290.0 -32500.0 -0.22 439580.0 59300.0 0.43 0.1485 0.308 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E19 compound treatment 291610.0 -78100.0 -0.53 339150.0 -41100.0 -0.3 -0.5838 -0.9632 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E20 compound treatment 435200.0 65400.0 0.44 455690.0 75400.0 0.55 0.6988 0.9945 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E21 mock treatment 416960.0 47200.0 0.32 328160.0 -52100.0 -0.38 -0.0411 -0.0833 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E22 compound treatment 420010.0 50300.0 0.34 365490.0 -14800.0 -0.11 0.1645 0.4621 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E23 compound treatment 266690.0 -103000.0 -0.7 272730.0 -108000.0 -0.78 -1.0428 -0.9985 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 E24 mock treatment 301610.0 -68100.0 -0.46 336400.0 -43900.0 -0.32 -0.5501 -0.9835 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F01 mock treatment 348430.0 -21300.0 -0.14 333840.0 -46400.0 -0.34 -0.3395 -0.9286 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F02 mock treatment 360860.0 -8900.0 -0.06 450560.0 70300.0 0.51 0.3174 0.6193 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F03 compound treatment 329630.0 -40100.0 -0.27 324590.0 -55700.0 -0.4 -0.4767 -0.9814 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F04 compound treatment 319320.0 -50400.0 -0.34 322880.0 -57400.0 -0.42 -0.5347 -0.9952 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F05 compound treatment 398890.0 29100.0 0.2 400160.0 19900.0 0.14 0.2411 0.9882 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F06 mock treatment 368720.0 -1040.0 -0.01 324610.0 -55600.0 -0.4 -0.2898 -0.7193 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F07 compound treatment 307840.0 -61900.0 -0.42 411770.0 31500.0 0.23 -0.1345 -0.2823 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F08 compound treatment 355250.0 -14500.0 -0.1 362020.0 -18200.0 -0.13 -0.1627 -0.9893 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F09 mock treatment 391330.0 21600.0 0.15 363910.0 -16300.0 -0.12 0.0194 0.1033 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F10 mock treatment 407540.0 37800.0 0.26 399420.0 19200.0 0.14 0.2786 0.9589 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F11 mock treatment 372430.0 2670.0 0.02 351970.0 -28300.0 -0.2 -0.132 -0.6423 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F12 compound treatment 285190.0 -84600.0 -0.57 251060.0 -129000.0 -0.94 -1.0654 -0.9721 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F13 compound treatment 320480.0 -49300.0 -0.33 388320.0 8060.0 0.06 -0.1942 -0.5744 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F14 compound treatment 40750.0 -329000.0 -2.22 12750.0 -368000.0 -2.66 -3.4531 -0.996 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F15 compound treatment 276420.0 -93300.0 -0.63 174980.0 -205000.0 -1.49 -1.4967 -0.9272 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F16 compound treatment 280210.0 -89500.0 -0.61 387440.0 7180.0 0.05 -0.3911 -0.644 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F17 mock treatment 333230.0 -36500.0 -0.25 405920.0 25700.0 0.19 -0.0432 -0.1397 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F18 mock treatment 386470.0 16700.0 0.11 360000.0 -20300.0 -0.15 -0.0238 -0.1288 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F19 compound treatment 321120.0 -48600.0 -0.33 312270.0 -68000.0 -0.49 -0.5804 -0.9807 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F20 compound treatment 265720.0 -104000.0 -0.7 365700.0 -14600.0 -0.11 -0.5716 -0.8041 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F21 compound treatment 270140.0 -99600.0 -0.67 307360.0 -72900.0 -0.53 -0.8491 -0.9927 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F22 compound treatment 326630.0 -43100.0 -0.29 299520.0 -80700.0 -0.58 -0.6193 -0.9483 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F23 compound treatment 393440.0 23700.0 0.16 434890.0 54600.0 0.4 0.3928 0.9207 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 F24 compound treatment 352120.0 -17600.0 -0.12 356960.0 -23300.0 -0.17 -0.2035 -0.9855 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G01 compound treatment 358670.0 -11100.0 -0.07 443450.0 63200.0 0.46 0.2705 0.5835 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G02 mock treatment 526950.0 157000.0 1.06 389600.0 9340.0 0.07 0.7989 0.7506 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G03 mock treatment 366290.0 -3470.0 -0.02 513790.0 134000.0 0.97 0.6669 0.6898 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G04 mock treatment 385250.0 15500.0 0.1 379520.0 -737.0 -0.01 0.0702 0.6702 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G05 compound treatment 305490.0 -64300.0 -0.43 448600.0 68300.0 0.49 0.0428 0.065 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G06 compound treatment 345160.0 -24600.0 -0.17 398080.0 17800.0 0.13 -0.0263 -0.125 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G07 compound treatment 295880.0 -73900.0 -0.5 461490.0 81200.0 0.59 0.0628 0.0815 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G08 mock treatment 444090.0 74300.0 0.5 466720.0 86500.0 0.63 0.7977 0.994 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G09 compound treatment 353980.0 -15800.0 -0.11 419090.0 38800.0 0.28 0.1234 0.4104 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G10 compound treatment 420010.0 50300.0 0.34 339370.0 -40900.0 -0.3 0.0308 0.0684 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G11 mock treatment 311840.0 -57900.0 -0.39 419810.0 39600.0 0.29 -0.0743 -0.1531 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G12 compound treatment 263970.0 -106000.0 -0.71 295410.0 -84800.0 -0.61 -0.9397 -0.9971 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G13 compound treatment 239620.0 -130000.0 -0.88 186720.0 -194000.0 -1.4 -1.6124 -0.9748 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G14 compound treatment 244090.0 -126000.0 -0.85 168640.0 -212000.0 -1.53 -1.6836 -0.9613 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G15 compound treatment 266940.0 -103000.0 -0.69 257310.0 -123000.0 -0.89 -1.1206 -0.9925 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G16 compound treatment 316670.0 -53100.0 -0.36 265850.0 -114000.0 -0.83 -0.8393 -0.9299 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G17 mock treatment 328190.0 -41600.0 -0.28 398840.0 18600.0 0.13 -0.1035 -0.3323 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G18 compound treatment 165630.0 -204000.0 -1.38 37760.0 -342000.0 -2.48 -2.7284 -0.9617 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G19 mock treatment 258370.0 -111000.0 -0.75 348730.0 -31500.0 -0.23 -0.6936 -0.8819 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G20 mock treatment 405440.0 35700.0 0.24 385280.0 5020.0 0.04 0.1962 0.8046 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G21 compound treatment 246880.0 -123000.0 -0.83 276740.0 -104000.0 -0.75 -1.117 -0.9987 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G22 compound treatment 281550.0 -88200.0 -0.6 349680.0 -30600.0 -0.22 -0.578 -0.909 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G23 compound treatment 306400.0 -63400.0 -0.43 297330.0 -82900.0 -0.6 -0.7272 -0.9863 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 G24 compound treatment 314320.0 -55400.0 -0.37 290250.0 -90000.0 -0.65 -0.7256 -0.9654 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H01 compound treatment 303370.0 -66400.0 -0.45 359580.0 -20700.0 -0.15 -0.423 -0.8946 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H02 compound treatment 383200.0 13400.0 0.09 267700.0 -113000.0 -0.81 -0.5119 -0.6244 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H03 mock treatment 289010.0 -80700.0 -0.55 426720.0 46500.0 0.34 -0.148 -0.2309 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H04 mock treatment 372010.0 2250.0 0.02 538370.0 158000.0 1.14 0.8201 0.7164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H05 compound treatment 479490.0 110000.0 0.74 440220.0 60000.0 0.43 0.8312 0.9675 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H06 compound treatment 299520.0 -70200.0 -0.47 332010.0 -48200.0 -0.35 -0.5825 -0.9886 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H07 compound treatment 277480.0 -92300.0 -0.62 269950.0 -110000.0 -0.8 -1.0055 -0.9925 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H08 compound treatment 448350.0 78600.0 0.53 373760.0 -6500.0 -0.05 0.3422 0.642 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H09 compound treatment 343360.0 -26400.0 -0.18 388110.0 7850.0 0.06 -0.0859 -0.459 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H10 compound treatment 340480.0 -29300.0 -0.2 403800.0 23500.0 0.17 -0.0194 -0.0742 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H11 compound treatment 305350.0 -64400.0 -0.44 441160.0 60900.0 0.44 0.004 0.0065 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H12 compound treatment 307360.0 -62400.0 -0.42 387920.0 7660.0 0.06 -0.2589 -0.6088 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H13 mock treatment 339040.0 -30700.0 -0.21 398730.0 18500.0 0.13 -0.0522 -0.2114 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H14 compound treatment 10240.0 -360000.0 -2.43 9470.0 -371000.0 -2.68 -3.6156 -0.9988 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H15 compound treatment 428170.0 58400.0 0.39 394300.0 14000.0 0.1 0.351 0.8611 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H16 compound treatment 382090.0 12300.0 0.08 373400.0 -6860.0 -0.05 0.0238 0.2456 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H17 compound treatment 231040.0 -139000.0 -0.94 324440.0 -55800.0 -0.4 -0.9485 -0.9293 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H18 compound treatment 320880.0 -48900.0 -0.33 313240.0 -67000.0 -0.49 -0.5766 -0.9824 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H19 mock treatment 268210.0 -102000.0 -0.69 381460.0 1200.0 0.01 -0.479 -0.6981 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H20 mock treatment 297760.0 -72000.0 -0.49 362530.0 -17700.0 -0.13 -0.4347 -0.8641 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H21 compound treatment 11690.0 -358000.0 -2.42 11840.0 -368000.0 -2.67 -3.5966 -0.9988 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H22 compound treatment 333820.0 -35900.0 -0.24 411100.0 30800.0 0.22 -0.0138 -0.0419 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H23 mock treatment 288580.0 -81200.0 -0.55 385090.0 4830.0 0.03 -0.3631 -0.6607 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 H24 compound treatment 256750.0 -113000.0 -0.76 441710.0 61500.0 0.44 -0.2254 -0.255 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I01 compound treatment 334480.0 -35300.0 -0.24 240440.0 -140000.0 -1.01 -0.8842 -0.8504 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I02 compound treatment 185400.0 -184000.0 -1.25 275860.0 -104000.0 -0.76 -1.4152 -0.9713 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I03 compound treatment 408090.0 38300.0 0.26 326250.0 -54000.0 -0.39 -0.0933 -0.1989 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I04 mock treatment 348860.0 -20900.0 -0.14 418500.0 38200.0 0.28 0.0959 0.3086 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I05 mock treatment 405680.0 35900.0 0.24 257120.0 -123000.0 -0.89 -0.4587 -0.4965 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I06 mock treatment 361010.0 -8750.0 -0.06 327120.0 -53100.0 -0.38 -0.3138 -0.8063 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I07 compound treatment 325090.0 -44700.0 -0.3 347230.0 -33000.0 -0.24 -0.3825 -0.9933 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I08 compound treatment 412690.0 42900.0 0.29 413440.0 33200.0 0.24 0.375 0.9956 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I09 compound treatment 421070.0 51300.0 0.35 360820.0 -19400.0 -0.14 0.1457 0.3893 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I10 compound treatment 239230.0 -131000.0 -0.88 373280.0 -6980.0 -0.05 -0.6593 -0.7464 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I11 compound treatment 303630.0 -66100.0 -0.45 351530.0 -28700.0 -0.21 -0.463 -0.9394 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I12 compound treatment 256390.0 -113000.0 -0.77 371590.0 -8670.0 -0.06 -0.586 -0.7625 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I13 compound treatment 57250.0 -313000.0 -2.11 37390.0 -343000.0 -2.48 -3.2481 -0.9968 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I14 compound treatment 19400.0 -350000.0 -2.37 45070.0 -335000.0 -2.43 -3.3897 -0.9999 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I15 compound treatment 405190.0 35400.0 0.24 458640.0 78400.0 0.57 0.5705 0.9264 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I16 compound treatment 299780.0 -70000.0 -0.47 298150.0 -82100.0 -0.59 -0.7546 -0.9936 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I17 compound treatment 266210.0 -104000.0 -0.7 328480.0 -51800.0 -0.37 -0.7598 -0.9572 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I18 compound treatment 234470.0 -135000.0 -0.91 223930.0 -156000.0 -1.13 -1.4466 -0.9944 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I19 compound treatment 229980.0 -140000.0 -0.94 277560.0 -103000.0 -0.74 -1.1935 -0.993 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I20 compound treatment 408270.0 38500.0 0.26 336440.0 -43800.0 -0.32 -0.0403 -0.0982 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I21 mock treatment 305450.0 -64300.0 -0.43 324410.0 -55800.0 -0.4 -0.5931 -0.9994 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I22 mock treatment 356200.0 -13600.0 -0.09 389510.0 9250.0 0.07 -0.0174 -0.1534 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I23 compound treatment 228100.0 -142000.0 -0.96 192740.0 -188000.0 -1.36 -1.6367 -0.9854 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 I24 compound treatment 378490.0 8730.0 0.06 343380.0 -36900.0 -0.27 -0.147 -0.5378 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J01 compound treatment 354050.0 -15700.0 -0.11 377660.0 -2600.0 -0.02 -0.0883 -0.8196 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J02 compound treatment 226480.0 -143000.0 -0.97 267490.0 -113000.0 -0.82 -1.2618 -0.9964 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J03 compound treatment 371800.0 2040.0 0.01 414820.0 34600.0 0.25 0.1867 0.745 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J04 mock treatment 228320.0 -141000.0 -0.96 418000.0 37700.0 0.27 -0.4826 -0.4855 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J05 mock treatment 419900.0 50100.0 0.34 413710.0 33500.0 0.24 0.4108 0.9864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J06 mock treatment 246750.0 -123000.0 -0.83 303430.0 -76800.0 -0.56 -0.981 -0.9809 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J07 compound treatment 293920.0 -75800.0 -0.51 328080.0 -52200.0 -0.38 -0.6294 -0.9887 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J08 compound treatment 424390.0 54600.0 0.37 452240.0 72000.0 0.52 0.6295 0.9857 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J09 compound treatment 320080.0 -49700.0 -0.34 292490.0 -87800.0 -0.64 -0.6866 -0.9555 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J10 compound treatment 303260.0 -66500.0 -0.45 245610.0 -135000.0 -0.97 -1.0069 -0.9382 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J11 compound treatment 257520.0 -112000.0 -0.76 361660.0 -18600.0 -0.13 -0.6314 -0.8198 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J12 compound treatment 205090.0 -165000.0 -1.11 228510.0 -152000.0 -1.1 -1.5635 -1.0 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J13 compound treatment 9550.0 -360000.0 -2.43 6020.0 -374000.0 -2.71 -3.6366 -0.9986 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J14 compound treatment 15430.0 -354000.0 -2.39 14880.0 -365000.0 -2.64 -3.5632 -0.9988 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J15 compound treatment 283780.0 -86000.0 -0.58 280550.0 -99700.0 -0.72 -0.9212 -0.9942 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J16 mock treatment 442090.0 72300.0 0.49 354580.0 -25700.0 -0.19 0.2142 0.4096 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J17 compound treatment 17880.0 -352000.0 -2.38 25840.0 -354000.0 -2.57 -3.4954 -0.9993 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J18 mock treatment 254690.0 -115000.0 -0.78 402880.0 22600.0 0.16 -0.434 -0.5462 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J19 compound treatment 265280.0 -104000.0 -0.71 306400.0 -73900.0 -0.53 -0.8772 -0.9906 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J20 compound treatment 312800.0 -57000.0 -0.38 344530.0 -35700.0 -0.26 -0.455 -0.9813 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J21 mock treatment 429380.0 59600.0 0.4 277640.0 -103000.0 -0.74 -0.2404 -0.2845 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J22 mock treatment 313920.0 -55800.0 -0.38 424640.0 44400.0 0.32 -0.0396 -0.0799 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J23 compound treatment 320220.0 -49500.0 -0.33 418610.0 38400.0 0.28 -0.0404 -0.0928 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 J24 compound treatment 279530.0 -90200.0 -0.61 239740.0 -141000.0 -1.02 -1.1504 -0.97 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K01 compound treatment 318490.0 -51300.0 -0.35 447470.0 67200.0 0.49 0.0991 0.1659 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K02 compound treatment 227360.0 -142000.0 -0.96 358110.0 -22100.0 -0.16 -0.7937 -0.8137 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K03 compound treatment 454360.0 84600.0 0.57 240800.0 -139000.0 -1.01 -0.3096 -0.2669 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K04 mock treatment 285680.0 -84100.0 -0.57 527960.0 148000.0 1.07 0.3543 0.2927 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K05 compound treatment 311700.0 -58100.0 -0.39 323160.0 -57100.0 -0.41 -0.5696 -0.9997 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K06 compound treatment 244760.0 -125000.0 -0.84 291270.0 -89000.0 -0.64 -1.0527 -0.9911 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K07 mock treatment 424430.0 54700.0 0.37 397570.0 17300.0 0.13 0.3498 0.8968 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K08 mock treatment 423010.0 53300.0 0.36 322930.0 -57300.0 -0.41 -0.039 -0.071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K09 compound treatment 317760.0 -52000.0 -0.35 424270.0 44000.0 0.32 -0.0231 -0.0488 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K10 compound treatment 166130.0 -204000.0 -1.38 362930.0 -17300.0 -0.13 -1.0616 -0.7684 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K11 compound treatment 328270.0 -41500.0 -0.28 266270.0 -114000.0 -0.83 -0.7817 -0.897 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K12 compound treatment 382210.0 12500.0 0.08 342920.0 -37300.0 -0.27 -0.1316 -0.465 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K13 mock treatment 421280.0 51500.0 0.35 569960.0 190000.0 1.37 1.2172 0.8592 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K14 compound treatment 263770.0 -106000.0 -0.72 311640.0 -68600.0 -0.5 -0.8576 -0.984 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K15 mock treatment 396360.0 26600.0 0.18 413280.0 33000.0 0.24 0.2961 0.9901 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K16 mock treatment 332910.0 -36800.0 -0.25 445920.0 65700.0 0.48 0.1601 0.2983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K17 compound treatment 358410.0 -11300.0 -0.08 326250.0 -54000.0 -0.39 -0.3307 -0.83 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K18 compound treatment 285660.0 -84100.0 -0.57 262930.0 -117000.0 -0.85 -1.0024 -0.9809 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K19 compound treatment 396360.0 26600.0 0.18 317800.0 -62500.0 -0.45 -0.1926 -0.3958 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K20 compound treatment 531040.0 161000.0 1.09 286300.0 -94000.0 -0.68 0.2896 0.2255 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K21 mock treatment 378530.0 8770.0 0.06 433820.0 53600.0 0.39 0.3161 0.8058 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K22 compound treatment 217140.0 -153000.0 -1.03 285700.0 -94600.0 -0.68 -1.2132 -0.9802 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K23 mock treatment 297760.0 -72000.0 -0.49 365320.0 -14900.0 -0.11 -0.4204 -0.8437 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 K24 mock treatment 331560.0 -38200.0 -0.26 393130.0 12900.0 0.09 -0.1166 -0.4249 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L01 mock treatment 493160.0 123000.0 0.83 548390.0 168000.0 1.22 1.4502 0.983 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L02 compound treatment 375940.0 6180.0 0.04 286910.0 -93300.0 -0.68 -0.4483 -0.6621 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L03 mock treatment 408810.0 39100.0 0.26 368840.0 -11400.0 -0.08 0.1281 0.4634 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L04 mock treatment 540040.0 170000.0 1.15 384840.0 4580.0 0.03 0.837 0.7272 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L05 compound treatment 283250.0 -86500.0 -0.58 390760.0 10500.0 0.08 -0.3596 -0.61 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L06 compound treatment 273440.0 -96300.0 -0.65 418910.0 38700.0 0.28 -0.2623 -0.3703 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L07 mock treatment 353080.0 -16700.0 -0.11 321060.0 -59200.0 -0.43 -0.3827 -0.8637 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L08 mock treatment 509680.0 140000.0 0.95 470560.0 90300.0 0.65 1.1308 0.9838 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L09 compound treatment 244800.0 -125000.0 -0.84 253930.0 -126000.0 -0.91 -1.2437 -0.9992 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L10 compound treatment 386610.0 16900.0 0.11 386400.0 6140.0 0.04 0.112 0.9159 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L11 compound treatment 325050.0 -44700.0 -0.3 419880.0 39600.0 0.29 -0.0108 -0.0259 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L12 compound treatment 464700.0 94900.0 0.64 327010.0 -53200.0 -0.39 0.1811 0.2419 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L13 compound treatment 9360.0 -360000.0 -2.44 8290.0 -372000.0 -2.69 -3.6259 -0.9987 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L14 compound treatment 8700.0 -361000.0 -2.44 8090.0 -372000.0 -2.69 -3.6301 -0.9988 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L15 mock treatment 369510.0 -247.0 0.0 405920.0 25700.0 0.19 0.1302 0.7007 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L16 mock treatment 406650.0 36900.0 0.25 467810.0 87600.0 0.63 0.6244 0.9169 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L17 compound treatment 310240.0 -59500.0 -0.4 151860.0 -228000.0 -1.65 -1.4535 -0.8542 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L18 compound treatment 71540.0 -298000.0 -2.02 74100.0 -306000.0 -2.22 -2.9919 -0.9989 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L19 compound treatment 317810.0 -51900.0 -0.35 306590.0 -73700.0 -0.53 -0.6253 -0.9794 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L20 mock treatment 383440.0 13700.0 0.09 448640.0 68400.0 0.5 0.4154 0.8249 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L21 compound treatment 299250.0 -70500.0 -0.48 519640.0 139000.0 1.01 0.3766 0.3375 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L22 compound treatment 319410.0 -50300.0 -0.34 434990.0 54700.0 0.4 0.0396 0.0759 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L23 mock treatment 355320.0 -14400.0 -0.1 356670.0 -23600.0 -0.17 -0.1897 -0.9647 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 L24 mock treatment 335140.0 -34600.0 -0.23 359100.0 -21200.0 -0.15 -0.2737 -0.9789 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M01 mock treatment 380550.0 10800.0 0.07 349440.0 -30800.0 -0.22 -0.1062 -0.4524 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M02 compound treatment 424640.0 54900.0 0.37 560000.0 180000.0 1.3 1.1823 0.8738 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M03 compound treatment 339220.0 -30500.0 -0.21 306930.0 -73300.0 -0.53 -0.5212 -0.9153 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M04 compound treatment 463460.0 93700.0 0.63 573210.0 193000.0 1.4 1.4354 0.936 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M05 compound treatment 413670.0 43900.0 0.3 513860.0 134000.0 0.97 0.8937 0.8834 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M06 compound treatment 358930.0 -10800.0 -0.07 291940.0 -88300.0 -0.64 -0.5038 -0.7829 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M07 compound treatment 360080.0 -9680.0 -0.07 291530.0 -88700.0 -0.64 -0.5004 -0.7751 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M08 compound treatment 405990.0 36200.0 0.24 235440.0 -145000.0 -1.05 -0.5682 -0.5278 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M09 mock treatment 404350.0 34600.0 0.23 304850.0 -75400.0 -0.55 -0.2207 -0.3717 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M10 mock treatment 497450.0 128000.0 0.86 346160.0 -34100.0 -0.25 0.4356 0.4854 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M11 compound treatment 380930.0 11200.0 0.08 278910.0 -101000.0 -0.73 -0.4654 -0.631 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M12 compound treatment 422080.0 52300.0 0.35 386980.0 6720.0 0.05 0.2844 0.7969 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M13 mock treatment 420890.0 51100.0 0.35 331920.0 -48300.0 -0.35 -0.0031 -0.0063 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M14 mock treatment 396170.0 26400.0 0.18 460920.0 80700.0 0.58 0.5391 0.8829 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M15 mock treatment 427680.0 57900.0 0.39 473440.0 93200.0 0.67 0.7537 0.9665 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M16 mock treatment 522020.0 152000.0 1.03 444590.0 64300.0 0.47 1.0568 0.9358 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M17 compound treatment 495010.0 125000.0 0.85 252370.0 -128000.0 -0.93 -0.0562 -0.0448 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M18 compound treatment 524350.0 155000.0 1.04 525550.0 145000.0 1.05 1.4823 1.0 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M19 compound treatment 313780.0 -56000.0 -0.38 261690.0 -119000.0 -0.86 -0.8744 -0.9322 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M20 compound treatment 233620.0 -136000.0 -0.92 440480.0 60200.0 0.44 -0.3422 -0.3361 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M21 compound treatment 426830.0 57100.0 0.39 365790.0 -14500.0 -0.1 0.1986 0.4971 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M22 compound treatment 344390.0 -25400.0 -0.17 229630.0 -151000.0 -1.09 -0.8922 -0.8083 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M23 compound treatment 309370.0 -60400.0 -0.41 468660.0 88400.0 0.64 0.164 0.2161 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 M24 compound treatment 248930.0 -121000.0 -0.82 260510.0 -120000.0 -0.87 -1.1902 -0.9996 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N01 compound treatment 396250.0 26500.0 0.18 312760.0 -67500.0 -0.49 -0.2189 -0.4207 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N02 mock treatment 358290.0 -11500.0 -0.08 442370.0 62100.0 0.45 0.2631 0.5768 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N03 compound treatment 254260.0 -115000.0 -0.78 406010.0 25800.0 0.19 -0.42 -0.5235 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N04 compound treatment 182290.0 -187000.0 -1.27 196910.0 -183000.0 -1.33 -1.8342 -0.9997 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N05 compound treatment 271010.0 -98700.0 -0.67 215000.0 -165000.0 -1.2 -1.3177 -0.962 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N06 compound treatment 501000.0 131000.0 0.89 371060.0 -9200.0 -0.07 0.58 0.6522 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N07 compound treatment 321280.0 -48500.0 -0.33 243070.0 -137000.0 -0.99 -0.9338 -0.893 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N08 compound treatment 290450.0 -79300.0 -0.54 418790.0 38500.0 0.28 -0.1817 -0.3007 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N09 mock treatment 382400.0 12600.0 0.09 480090.0 99800.0 0.72 0.5714 0.7852 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N10 mock treatment 318670.0 -51100.0 -0.35 502960.0 123000.0 0.89 0.384 0.403 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N11 mock treatment 376560.0 6800.0 0.05 385890.0 5630.0 0.04 0.0613 0.9982 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N12 compound treatment 475700.0 106000.0 0.72 207150.0 -173000.0 -1.25 -0.3799 -0.2632 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N13 mock treatment 457890.0 88100.0 0.6 474170.0 93900.0 0.68 0.9018 0.9978 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N14 mock treatment 471480.0 102000.0 0.69 455290.0 75000.0 0.54 0.8701 0.9932 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N15 compound treatment 306560.0 -63200.0 -0.43 291840.0 -88400.0 -0.64 -0.7545 -0.9806 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N16 compound treatment 101880.0 -268000.0 -1.81 46510.0 -334000.0 -2.42 -2.9882 -0.9899 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N17 compound treatment 405150.0 35400.0 0.24 277390.0 -103000.0 -0.74 -0.3574 -0.457 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N18 compound treatment 488320.0 119000.0 0.8 299000.0 -81300.0 -0.59 0.1505 0.1515 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N19 compound treatment 274640.0 -95100.0 -0.64 427270.0 47000.0 0.34 -0.2138 -0.294 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N20 compound treatment 213540.0 -156000.0 -1.06 241220.0 -139000.0 -1.01 -1.4581 -0.9997 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N21 mock treatment 300370.0 -69400.0 -0.47 332240.0 -48000.0 -0.35 -0.5773 -0.9892 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N22 compound treatment 210170.0 -160000.0 -1.08 305670.0 -74600.0 -0.54 -1.1443 -0.9489 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N23 compound treatment 462560.0 92800.0 0.63 275580.0 -105000.0 -0.76 -0.0924 -0.094 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 N24 mock treatment 490680.0 121000.0 0.82 380640.0 383.0 0.0 0.5797 0.7095 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O01 compound treatment 308640.0 -61100.0 -0.41 295770.0 -84500.0 -0.61 -0.7245 -0.9817 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O02 compound treatment 386740.0 17000.0 0.11 390880.0 10600.0 0.08 0.1355 0.9811 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O03 compound treatment 240500.0 -129000.0 -0.87 314150.0 -66100.0 -0.48 -0.9559 -0.9599 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O04 compound treatment 249390.0 -120000.0 -0.81 443580.0 63300.0 0.46 -0.251 -0.2688 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O05 compound treatment 222630.0 -147000.0 -0.99 273280.0 -107000.0 -0.77 -1.2505 -0.9924 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O06 compound treatment 290370.0 -79400.0 -0.54 259410.0 -121000.0 -0.87 -0.9979 -0.9724 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O07 mock treatment 379680.0 9920.0 0.07 398130.0 17900.0 0.13 0.1389 0.9532 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O08 mock treatment 350240.0 -19500.0 -0.13 349620.0 -30600.0 -0.22 -0.2501 -0.9692 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O09 mock treatment 420320.0 50600.0 0.34 319840.0 -60400.0 -0.44 -0.0677 -0.1219 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O10 compound treatment 417320.0 47600.0 0.32 324330.0 -55900.0 -0.4 -0.059 -0.1142 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O11 mock treatment 387520.0 17800.0 0.12 379550.0 -707.0 -0.01 0.0812 0.6763 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O12 mock treatment 427070.0 57300.0 0.39 276250.0 -104000.0 -0.75 -0.2586 -0.3054 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O13 compound treatment 19150.0 -351000.0 -2.37 30690.0 -350000.0 -2.53 -3.4645 -0.9995 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O14 compound treatment 26720.0 -343000.0 -2.32 29450.0 -351000.0 -2.54 -3.4346 -0.999 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O15 compound treatment 441650.0 71900.0 0.49 402900.0 22600.0 0.16 0.4594 0.8961 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O16 compound treatment 13160.0 -357000.0 -2.41 17600.0 -363000.0 -2.63 -3.5601 -0.9991 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O17 compound treatment 214500.0 -155000.0 -1.05 340260.0 -40000.0 -0.29 -0.9465 -0.8697 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O18 compound treatment 218880.0 -151000.0 -1.02 196500.0 -184000.0 -1.33 -1.6615 -0.9914 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O19 compound treatment 291730.0 -78000.0 -0.53 498040.0 118000.0 0.85 0.2301 0.2295 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O20 mock treatment 300850.0 -68900.0 -0.47 436750.0 56500.0 0.41 -0.0401 -0.0646 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O21 mock treatment 440830.0 71100.0 0.48 307950.0 -72300.0 -0.52 -0.0305 -0.043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O22 compound treatment 278820.0 -90900.0 -0.61 355200.0 -25100.0 -0.18 -0.5627 -0.8784 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O23 compound treatment 343360.0 -26400.0 -0.18 360640.0 -19600.0 -0.14 -0.2265 -0.9936 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 O24 compound treatment 309200.0 -60600.0 -0.41 348590.0 -31700.0 -0.23 -0.4514 -0.9625 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P01 compound treatment 229730.0 -140000.0 -0.95 257170.0 -123000.0 -0.89 -1.2991 -0.9996 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P02 mock treatment 277770.0 -92000.0 -0.62 333230.0 -47000.0 -0.34 -0.6802 -0.9599 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P03 mock treatment 256640.0 -113000.0 -0.76 355470.0 -24800.0 -0.18 -0.6673 -0.85 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P04 compound treatment 224240.0 -146000.0 -0.98 228730.0 -152000.0 -1.1 -1.4709 -0.9985 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P05 compound treatment 128060.0 -242000.0 -1.63 134560.0 -246000.0 -1.78 -2.4124 -0.9991 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P06 compound treatment 237300.0 -132000.0 -0.89 225940.0 -154000.0 -1.12 -1.4228 -0.994 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P07 compound treatment 225190.0 -145000.0 -0.98 273210.0 -107000.0 -0.77 -1.2387 -0.9934 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P08 compound treatment 179060.0 -191000.0 -1.29 220280.0 -160000.0 -1.16 -1.73 -0.9986 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P09 mock treatment 256090.0 -114000.0 -0.77 285170.0 -95100.0 -0.69 -1.0298 -0.9985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P10 compound treatment 245470.0 -124000.0 -0.84 237200.0 -143000.0 -1.04 -1.3261 -0.9946 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P11 mock treatment 263320.0 -106000.0 -0.72 295220.0 -85000.0 -0.62 -0.9438 -0.997 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P12 mock treatment 250490.0 -119000.0 -0.81 297030.0 -83200.0 -0.6 -0.9958 -0.9897 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P13 compound treatment 236890.0 -133000.0 -0.9 186650.0 -194000.0 -1.4 -1.6258 -0.9768 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P14 compound treatment 23140.0 -347000.0 -2.34 16160.0 -364000.0 -2.64 -3.5198 -0.9983 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P15 compound treatment 254900.0 -115000.0 -0.78 195370.0 -185000.0 -1.34 -1.4951 -0.9664 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P16 compound treatment 260050.0 -110000.0 -0.74 238820.0 -141000.0 -1.02 -1.2481 -0.9874 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P17 compound treatment 300480.0 -69300.0 -0.47 236360.0 -144000.0 -1.04 -1.0676 -0.9348 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P18 compound treatment 189150.0 -181000.0 -1.22 230450.0 -150000.0 -1.08 -1.6297 -0.9983 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P19 compound treatment 240830.0 -129000.0 -0.87 245810.0 -134000.0 -0.97 -1.3042 -0.9985 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P20 mock treatment 212800.0 -157000.0 -1.06 244800.0 -135000.0 -0.98 -1.4433 -0.9992 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P21 compound treatment 151370.0 -218000.0 -1.48 249300.0 -131000.0 -0.95 -1.7137 -0.9771 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P22 compound treatment 102190.0 -268000.0 -1.81 100610.0 -280000.0 -2.02 -2.7098 -0.9984 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P23 compound treatment 236320.0 -133000.0 -0.9 193810.0 -186000.0 -1.35 -1.5919 -0.9808 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.2284 P24 mock treatment 194720.0 -175000.0 -1.18 232380.0 -148000.0 -1.07 -1.5932 -0.9988 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A01 mock treatment 351840.0 -55900.0 -0.38 379100.0 -25200.0 -0.18 -0.0846 -0.1221 469650.0 79310.157480315 0.533212022850976 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A02 mock treatment 487290.0 79500.0 0.54 295520.0 -109000.0 -0.79 -0.3234 -0.3028 402020.0 11680.157480315 0.0785271470283303 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A03 mock treatment 328610.0 -79200.0 -0.53 353060.0 -51300.0 -0.37 -1.2568 -0.9244 309040.0 -81299.842519685 -0.546588922082857 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A04 mock treatment 330810.0 -77000.0 -0.52 435580.0 31300.0 0.23 -0.8943 -0.7423 267250.0 -123089.842519685 -0.827548273859116 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A05 mock treatment 429400.0 21600.0 0.15 300890.0 -103000.0 -0.75 -0.5259 -0.5042 290000.0 -100339.842519685 -0.674597202959142 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A06 mock treatment 496850.0 89100.0 0.6 429600.0 25300.0 0.18 0.0708 0.0777 292320.0 -98019.842519685 -0.658999555289343 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A07 mock treatment 293940.0 -114000.0 -0.77 324900.0 -79400.0 -0.57 -1.4735 -0.9762 299240.0 -91099.842519685 -0.612475537239769 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A08 mock treatment 362660.0 -45100.0 -0.3 404750.0 420.0 0.0 -0.5624 -0.7816 360000.0 -30339.842519685 -0.203978523266917 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A09 mock treatment 453650.0 45900.0 0.31 377850.0 -26500.0 -0.19 -0.1788 -0.3499 367850.0 -22489.842519685 -0.151201999901432 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A10 mock treatment 379330.0 -28400.0 -0.19 464430.0 60100.0 0.44 -0.1125 -0.1763 327470.0 -62869.842519685 -0.42268174684389 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A11 mock treatment 499240.0 91500.0 0.62 373600.0 -30700.0 -0.22 0.0897 0.1147 332480.0 -57859.842519685 -0.388998895625918 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A12 mock treatment 435330.0 27600.0 0.19 363420.0 -40900.0 -0.3 -0.5595 -0.7041 315760.0 -74579.842519685 -0.501409528832404 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A13 mock treatment 452640.0 44900.0 0.3 296230.0 -108000.0 -0.78 -0.2156 -0.2392 428390.0 38050.157480315 0.255815926792387 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A14 mock treatment 334680.0 -73100.0 -0.49 417800.0 13500.0 0.1 -0.0932 -0.1773 402940.0 12600.157480315 0.0847124211042853 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A15 mock treatment 376070.0 -31700.0 -0.21 352640.0 -51700.0 -0.37 -0.1818 -0.3305 438850.0 48510.157480315 0.326139803786397 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A16 mock treatment 373650.0 -34100.0 -0.23 411860.0 7530.0 0.05 -0.2405 -0.4327 319890.0 -70449.842519685 -0.473643026730562 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A17 mock treatment 392770.0 -15000.0 -0.1 347520.0 -56800.0 -0.41 -0.3059 -0.6883 370900.0 -19439.842519685 -0.130696471714842 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A18 mock treatment 277440.0 -130000.0 -0.88 276290.0 -128000.0 -0.93 -0.7766 -0.5921 384960.0 -5379.84251968499 -0.0361693483366606 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A19 mock treatment 366080.0 -41700.0 -0.28 348830.0 -55500.0 -0.4 -0.4271 -0.8442 374910.0 -15429.842519685 -0.103736744492473 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A20 mock treatment 306190.0 -102000.0 -0.69 261480.0 -143000.0 -1.03 -0.8162 -0.641 367750.0 -22589.842519685 -0.151874312300992 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A21 mock treatment 289790.0 -118000.0 -0.8 379960.0 -24400.0 -0.18 -0.4422 -0.5308 380850.0 -9489.84251968499 -0.0638013879585899 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A22 mock treatment 326570.0 -81200.0 -0.55 347740.0 -56600.0 -0.41 -0.3019 -0.4111 425990.0 35650.157480315 0.23968042920294 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A23 mock treatment 276590.0 -131000.0 -0.89 323600.0 -80700.0 -0.58 -0.8724 -0.8082 372220.0 -18119.842519685 -0.121821948040646 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base A24 mock treatment 259630.0 -148000.0 -1.0 212100.0 -192000.0 -1.39 -1.7296 -0.9234 307720.0 -82619.842519685 -0.555463445757053 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B01 mock treatment 527010.0 119000.0 0.81 473720.0 69400.0 0.5 0.9653 0.9086 417440.0 27100.157480315 0.182197719040532 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B02 mock treatment 480380.0 72600.0 0.49 432100.0 27800.0 0.2 0.5335 0.4315 304160.0 -86179.842519685 -0.579397767181401 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B03 mock treatment 464110.0 56300.0 0.38 308920.0 -95400.0 -0.69 0.5675 0.4284 529130.0 138790.157480315 0.933103438109456 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B04 mock treatment 503080.0 95300.0 0.64 456720.0 52400.0 0.38 0.9401 0.9329 422560.0 32220.157480315 0.21662011389802 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B05 mock treatment 502580.0 94800.0 0.64 404800.0 470.0 0.0 0.4169 0.515 454560.0 64220.157480315 0.431760081757324 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B06 mock treatment 307360.0 -100000.0 -0.68 445700.0 41400.0 0.3 -0.3177 -0.3889 340690.0 -49649.842519685 -0.333802047622015 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B07 mock treatment 465670.0 57900.0 0.39 455680.0 51400.0 0.37 -0.0971 -0.1105 303390.0 -86949.842519685 -0.584574572658015 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B08 mock treatment 513520.0 106000.0 0.71 441970.0 37600.0 0.27 0.3017 0.2826 434730.0 44390.157480315 0.298440532924512 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B09 mock treatment 453380.0 45600.0 0.31 310900.0 -93400.0 -0.68 -0.9726 -0.725 279690.0 -110649.842519685 -0.743912611353812 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B10 mock treatment 346660.0 -61100.0 -0.41 468060.0 63700.0 0.46 -0.0423 -0.0658 365180.0 -25159.842519685 -0.169152740969692 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B11 mock treatment 495240.0 87500.0 0.59 467450.0 63100.0 0.46 0.3981 0.431 317640.0 -72699.842519685 -0.488770055720669 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B12 mock treatment 422720.0 14900.0 0.1 337140.0 -67200.0 -0.49 -0.4209 -0.5879 314120.0 -76219.842519685 -0.512435452185193 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B13 mock treatment 438150.0 30400.0 0.21 470590.0 66300.0 0.48 0.499 0.8112 388480.0 -1859.84251968499 -0.0125039518721373 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B14 mock treatment 373940.0 -33800.0 -0.23 401610.0 -2720.0 -0.02 0.2431 0.4133 461120.0 70780.157480315 0.475863775168481 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B15 mock treatment 340320.0 -67500.0 -0.46 462460.0 58100.0 0.42 -0.1386 -0.2048 350310.0 -40029.842519685 -0.269125594784312 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B16 mock treatment 398920.0 -8850.0 -0.06 484510.0 80200.0 0.58 0.3781 0.5878 430320.0 39980.157480315 0.268791556103901 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B17 mock treatment 498400.0 90600.0 0.61 304860.0 -99500.0 -0.72 -0.1732 -0.1779 355520.0 -34819.842519685 -0.234098118767219 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B18 mock treatment 419540.0 11800.0 0.08 339740.0 -64600.0 -0.47 -0.154 -0.3007 415680.0 25340.157480315 0.17036502080827 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B19 mock treatment 355050.0 -52700.0 -0.36 360760.0 -43600.0 -0.32 -0.4433 -0.8649 386450.0 -3889.84251968499 -0.0261518935832118 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B20 mock treatment 264850.0 -143000.0 -0.97 332110.0 -72200.0 -0.52 -0.5774 -0.5122 405130.0 14790.157480315 0.0994360626546563 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B21 mock treatment 377180.0 -30600.0 -0.21 415130.0 10800.0 0.08 0.0042 0.0155 387840.0 -2499.84251968499 -0.0168067512293233 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B22 mock treatment 381250.0 -26500.0 -0.18 428640.0 24300.0 0.18 0.1481 0.4108 396980.0 6640.15748031501 0.0446426020904901 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B23 mock treatment 311210.0 -96600.0 -0.65 401860.0 -2470.0 -0.02 -0.3136 -0.4591 372640.0 -17699.842519685 -0.118998235962492 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base B24 mock treatment 284480.0 -123000.0 -0.83 424350.0 20000.0 0.14 -0.5184 -0.5789 381440.0 -8899.84251968499 -0.059834744801184 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C01 mock treatment 419960.0 12200.0 0.08 423880.0 19600.0 0.14 0.1151 0.7024 391290.0 950.157480315014 0.00638802655550777 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C02 mock treatment 361000.0 -46800.0 -0.32 469760.0 65400.0 0.47 -0.0869 -0.1201 325600.0 -64739.842519685 -0.435253988715668 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C03 mock treatment 317530.0 -90200.0 -0.61 447630.0 43300.0 0.31 -0.4623 -0.5399 370600.0 -19739.842519685 -0.132713408913523 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C04 mock treatment 388320.0 -19500.0 -0.13 476720.0 72400.0 0.52 -0.3662 -0.361 340680.0 -49659.842519685 -0.333869278861971 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C05 mock treatment 426690.0 18900.0 0.13 419240.0 14900.0 0.11 -0.2044 -0.4088 354940.0 -35399.842519685 -0.237997530684669 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C06 mock treatment 431530.0 23800.0 0.16 391940.0 -12400.0 -0.09 -0.0524 -0.0959 324770.0 -65569.842519685 -0.440834181632018 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C07 mock treatment 466830.0 59100.0 0.4 420190.0 15900.0 0.11 -0.0303 -0.0372 287430.0 -102909.842519685 -0.691875631627843 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C08 mock treatment 416960.0 9190.0 0.06 423710.0 19400.0 0.14 0.0204 0.0467 336990.0 -53349.842519685 -0.358677606405747 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C09 mock treatment 479560.0 71800.0 0.49 473540.0 69200.0 0.5 0.4034 0.5056 338470.0 -51869.842519685 -0.348727382892254 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C10 mock treatment 461070.0 53300.0 0.36 430170.0 25800.0 0.19 0.0712 0.1305 336420.0 -53919.842519685 -0.362509787083241 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C11 mock treatment 456590.0 48800.0 0.33 438790.0 34500.0 0.25 -0.127 -0.1699 307360.0 -82979.842519685 -0.557883770395471 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C12 mock treatment 443060.0 35300.0 0.24 383950.0 -20400.0 -0.15 0.0973 0.1587 341250.0 -49089.842519685 -0.330037098184477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C13 mock treatment 454290.0 46500.0 0.31 442910.0 38600.0 0.28 0.4224 0.9173 402640.0 12300.157480315 0.0826954839056043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C14 mock treatment 316400.0 -91400.0 -0.62 417780.0 13500.0 0.1 -0.4488 -0.6358 342200.0 -48139.842519685 -0.323650130388654 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C15 mock treatment 374720.0 -33100.0 -0.22 426820.0 22500.0 0.16 -0.0835 -0.1804 344200.0 -46139.842519685 -0.310203882397448 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C16 mock treatment 418880.0 11100.0 0.08 426960.0 22600.0 0.16 -0.037 -0.1139 350660.0 -39679.842519685 -0.266772501385851 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C17 mock treatment 414760.0 6990.0 0.05 445310.0 41000.0 0.3 0.0584 0.1681 366330.0 -24009.842519685 -0.161421148374749 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C18 mock treatment 372960.0 -34800.0 -0.24 364370.0 -40000.0 -0.29 -0.355 -0.8684 387520.0 -2819.84251968499 -0.0189581509079164 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C19 mock treatment 406460.0 -1310.0 -0.01 401280.0 -3050.0 -0.02 -0.2782 -0.7472 351330.0 -39009.842519685 -0.262268008308797 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C20 mock treatment 407000.0 -771.0 -0.01 340570.0 -63800.0 -0.46 -0.6015 -0.8548 346650.0 -43689.842519685 -0.29373222860822 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C21 mock treatment 397150.0 -10600.0 -0.07 363130.0 -41200.0 -0.3 -0.2613 -0.7573 391130.0 790.157480315014 0.00531232671621125 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C22 mock treatment 234370.0 -173000.0 -1.17 362360.0 -42000.0 -0.3 -1.1168 -0.7887 281130.0 -109209.842519685 -0.734231312800143 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C23 mock treatment 373520.0 -34300.0 -0.23 315640.0 -88700.0 -0.64 -0.4599 -0.6614 400490.0 10150.157480315 0.0682407673150574 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base C24 mock treatment 346310.0 -61500.0 -0.42 346290.0 -58000.0 -0.42 -0.6089 -0.9262 372480.0 -17859.842519685 -0.120073935801789 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D01 mock treatment 435040.0 27300.0 0.18 502480.0 98200.0 0.71 0.9584 0.9089 442620.0 52280.157480315 0.351485981249821 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D02 mock treatment 306790.0 -101000.0 -0.68 251450.0 -153000.0 -1.11 -0.556 -0.3932 470400.0 80060.157480315 0.538254365847679 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D03 mock treatment 443880.0 36100.0 0.24 301280.0 -103000.0 -0.75 -0.5728 -0.5725 386840.0 -3499.84251968499 -0.0235298752249266 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D04 mock treatment 519910.0 112000.0 0.76 473530.0 69200.0 0.5 0.5387 0.5173 325000.0 -65339.842519685 -0.43928786311303 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D05 mock treatment 472480.0 64700.0 0.44 427600.0 23300.0 0.17 0.1307 0.2267 389080.0 -1259.84251968499 -0.00847007747477535 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D06 mock treatment 403930.0 -3840.0 -0.03 459200.0 54900.0 0.4 0.811 0.8081 510490.0 120150.157480315 0.807784406831412 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D07 mock treatment 379840.0 -27900.0 -0.19 397600.0 -6730.0 -0.05 -0.0062 -0.0108 461090.0 70750.157480315 0.475662081448613 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D08 mock treatment 468410.0 60600.0 0.41 449220.0 44900.0 0.32 0.1353 0.1921 320170.0 -70169.842519685 -0.471760552011793 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D09 mock treatment 474810.0 67000.0 0.45 489240.0 84900.0 0.61 0.619 0.7942 392500.0 2160.15748031501 0.0145230065901877 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D10 mock treatment 522910.0 115000.0 0.78 451520.0 47200.0 0.34 0.9865 0.9442 461670.0 71330.157480315 0.479561493366062 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D11 mock treatment 470500.0 62700.0 0.42 430140.0 25800.0 0.19 0.6065 0.9609 429960.0 39620.157480315 0.266371231465484 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D12 mock treatment 462320.0 54500.0 0.37 359240.0 -45100.0 -0.33 -0.3124 -0.4553 348800.0 -41539.842519685 -0.279277512017673 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D13 mock treatment 511300.0 104000.0 0.7 489970.0 85600.0 0.62 0.9545 0.9325 432570.0 42230.157480315 0.283918585094009 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D14 mock treatment 461440.0 53700.0 0.36 423080.0 18800.0 0.14 0.6911 0.9057 434570.0 44230.157480315 0.297364833085215 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D15 mock treatment 417850.0 10100.0 0.07 433300.0 29000.0 0.21 0.3101 0.9372 410820.0 20480.157480315 0.137690638189639 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D16 mock treatment 457050.0 49300.0 0.33 421980.0 17700.0 0.13 0.1785 0.4855 377280.0 -13059.842519685 -0.0878029406228934 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D17 mock treatment 388960.0 -18800.0 -0.13 456440.0 52100.0 0.38 0.4172 0.7146 422430.0 32090.157480315 0.215746107778592 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D18 mock treatment 409400.0 1630.0 0.01 375040.0 -29300.0 -0.21 0.0314 0.1092 404580.0 14240.157480315 0.0957383444570746 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D19 mock treatment 384660.0 -23100.0 -0.16 478720.0 74400.0 0.54 0.1679 0.2903 372350.0 -17989.842519685 -0.120947941921217 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D20 mock treatment 383230.0 -24500.0 -0.17 395420.0 -8910.0 -0.06 -0.0502 -0.1632 375410.0 -14929.842519685 -0.100375182494671 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D21 mock treatment 385780.0 -22000.0 -0.15 436340.0 32000.0 0.23 0.3142 0.6433 418400.0 28060.157480315 0.188651918076311 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D22 mock treatment 345050.0 -62700.0 -0.42 318720.0 -85600.0 -0.62 -0.3698 -0.4674 399550.0 9210.15748031501 0.0619210307591904 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D23 mock treatment 425600.0 17800.0 0.12 283530.0 -121000.0 -0.87 -0.588 -0.6076 331470.0 -58869.842519685 -0.395789250861477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base D24 mock treatment 302120.0 -106000.0 -0.71 432160.0 27800.0 0.2 -0.3253 -0.4306 369000.0 -21339.842519685 -0.143470407306488 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E01 mock treatment 459310.0 51500.0 0.35 497960.0 93600.0 0.68 0.494 0.5737 429600.0 39260.157480315 0.263950906827067 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E02 mock treatment 466590.0 58800.0 0.4 366000.0 -38300.0 -0.28 0.7423 0.6848 481920.0 91580.157480315 0.615704754277028 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E03 mock treatment 389920.0 -17900.0 -0.12 522610.0 118000.0 0.86 0.1758 0.1673 417770.0 27430.157480315 0.184416349959081 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E04 mock treatment 519250.0 111000.0 0.75 375680.0 -28600.0 -0.21 0.224 0.2326 441880.0 51540.157480315 0.346510869493075 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E05 mock treatment 469190.0 61400.0 0.41 464290.0 60000.0 0.43 0.371 0.3661 467840.0 77500.157480315 0.521043168418934 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E06 mock treatment 478950.0 71200.0 0.48 504960.0 101000.0 0.73 0.5377 0.5836 409720.0 19380.157480315 0.130295201794475 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E07 mock treatment 442330.0 34600.0 0.23 343910.0 -60400.0 -0.44 -0.1109 -0.2067 367410.0 -22929.842519685 -0.154160174459497 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E08 mock treatment 447610.0 39800.0 0.27 427810.0 23500.0 0.17 0.5973 0.8499 412090.0 21750.157480315 0.146229005664055 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E09 mock treatment 445120.0 37300.0 0.25 490980.0 86700.0 0.63 0.3261 0.3066 288760.0 -101579.842519685 -0.68293387671369 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E10 mock treatment 456330.0 48600.0 0.33 434650.0 30300.0 0.22 0.2094 0.5146 384700.0 -5639.84251968499 -0.0379173605755175 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E11 mock treatment 466950.0 59200.0 0.4 450190.0 45900.0 0.33 0.5525 0.6938 475160.0 84820.157480315 0.57025643606675 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E12 mock treatment 492320.0 84500.0 0.57 423540.0 19200.0 0.14 0.4145 0.5948 437520.0 47180.157480315 0.317198048872245 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E13 mock treatment 474590.0 66800.0 0.45 406210.0 1880.0 0.01 0.5897 0.8447 425800.0 35460.157480315 0.238403035643775 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E14 mock treatment 466480.0 58700.0 0.4 406760.0 2430.0 0.02 0.5008 0.8275 414020.0 23680.157480315 0.159204634975569 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E15 mock treatment 471260.0 63500.0 0.43 427910.0 23600.0 0.17 0.556 0.9019 448290.0 57950.157480315 0.389606094304891 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E16 mock treatment 468000.0 60200.0 0.41 375110.0 -29200.0 -0.21 0.3937 0.6262 423960.0 33620.157480315 0.226032487491865 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E17 mock treatment 417020.0 9250.0 0.06 472340.0 68000.0 0.49 0.5171 0.8061 402400.0 12060.157480315 0.0810819341466596 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E18 mock treatment 456280.0 48500.0 0.33 411430.0 7100.0 0.05 0.3431 0.7623 390770.0 430.157480315014 0.00289200207779409 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E19 mock treatment 379040.0 -28700.0 -0.19 441010.0 36700.0 0.27 0.1835 0.462 404260.0 13920.157480315 0.0935869447784815 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E20 mock treatment 417440.0 9670.0 0.07 353040.0 -51300.0 -0.37 -0.0599 -0.1078 363610.0 -26729.842519685 -0.179708045642789 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E21 mock treatment 287130.0 -121000.0 -0.82 348370.0 -56000.0 -0.41 -0.4253 -0.4445 432160.0 41820.157480315 0.281162104255811 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E22 mock treatment 290080.0 -118000.0 -0.8 414080.0 9750.0 0.07 -0.303 -0.3771 395360.0 5020.15748031501 0.0337511412176129 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E23 mock treatment 290670.0 -117000.0 -0.79 316120.0 -88200.0 -0.64 -0.8594 -0.8282 365480.0 -24859.842519685 -0.167135803771011 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base E24 mock treatment 331460.0 -76300.0 -0.52 288120.0 -116000.0 -0.84 -0.9946 -0.8624 301700.0 -88639.842519685 -0.595936652210585 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F01 mock treatment 421070.0 13300.0 0.09 376720.0 -27600.0 -0.2 -0.3162 -0.4299 414290.0 23950.157480315 0.161019878454382 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F02 mock treatment 501770.0 94000.0 0.64 360590.0 -43700.0 -0.32 -0.2309 -0.2551 321130.0 -69209.842519685 -0.465306352976014 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F03 mock treatment 345980.0 -61800.0 -0.42 511850.0 108000.0 0.78 0.6892 0.6049 467630.0 77290.157480315 0.519631312379858 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F04 mock treatment 363850.0 -43900.0 -0.3 437700.0 33400.0 0.24 0.2408 0.2475 515470.0 125130.157480315 0.841265564329516 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F05 mock treatment 505930.0 98200.0 0.66 500800.0 96500.0 0.7 0.7124 0.6286 457680.0 67340.157480315 0.452736228623606 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F06 mock treatment 430280.0 22500.0 0.15 416720.0 12400.0 0.09 0.0906 0.4881 389870.0 -469.842519684986 -0.00315880951824881 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F07 mock treatment 435370.0 27600.0 0.19 454100.0 49800.0 0.36 0.5168 0.8916 402360.0 12020.157480315 0.0808130091868354 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F08 mock treatment 539580.0 132000.0 0.89 451730.0 47400.0 0.34 0.713 0.6643 454250.0 63910.157480315 0.429675913318687 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F09 mock treatment 459590.0 51800.0 0.35 471930.0 67600.0 0.49 0.4449 0.6355 356650.0 -33689.842519685 -0.226500988652188 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F10 mock treatment 382400.0 -25400.0 -0.17 388960.0 -15400.0 -0.11 0.6139 0.5524 478570.0 88230.157480315 0.593182288891757 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F11 mock treatment 524970.0 117000.0 0.79 380320.0 -24000.0 -0.17 0.8377 0.7339 438010.0 47670.157480315 0.32049237963009 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F12 mock treatment 438040.0 30300.0 0.2 395010.0 -9320.0 -0.07 -0.0517 -0.1878 370080.0 -20259.842519685 -0.136209433391237 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F13 mock treatment 440530.0 32800.0 0.22 476550.0 72200.0 0.52 0.3449 0.5769 366990.0 -23349.842519685 -0.156983886537651 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F14 mock treatment 454290.0 46500.0 0.31 382770.0 -21600.0 -0.16 0.4926 0.7147 462370.0 72030.157480315 0.484267680162985 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F15 mock treatment 455570.0 47800.0 0.32 416870.0 12500.0 0.09 0.235 0.4281 349020.0 -41319.842519685 -0.27779842473864 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F16 mock treatment 443840.0 36100.0 0.24 443520.0 39200.0 0.28 0.7203 0.95 444130.0 53790.157480315 0.361637898483182 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F17 mock treatment 365300.0 -42500.0 -0.29 421350.0 17000.0 0.12 0.2114 0.3547 403170.0 12830.157480315 0.086258739623274 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F18 mock treatment 380160.0 -27600.0 -0.19 439420.0 35100.0 0.25 0.3335 0.6197 424130.0 33790.157480315 0.227175418571118 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F19 mock treatment 371440.0 -36300.0 -0.25 408160.0 3830.0 0.03 0.1303 0.1998 478480.0 88140.157480315 0.592577207732153 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F20 mock treatment 398500.0 -9270.0 -0.06 418690.0 14400.0 0.1 0.1213 0.3003 442960.0 52620.157480315 0.353771843408326 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F21 mock treatment 465000.0 57200.0 0.39 409010.0 4680.0 0.03 0.1265 0.218 334250.0 -56089.842519685 -0.3770989661537 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F22 mock treatment 396960.0 -10800.0 -0.07 375910.0 -28400.0 -0.21 -0.3583 -0.5181 418640.0 28300.157480315 0.190265467835256 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F23 mock treatment 374520.0 -33300.0 -0.22 427640.0 23300.0 0.17 0.0264 0.0679 425400.0 35060.157480315 0.235713786045534 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base F24 mock treatment 388750.0 -19000.0 -0.13 280020.0 -124000.0 -0.9 -0.6255 -0.6587 350080.0 -40259.842519685 -0.270671913303301 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G01 mock treatment 422630.0 14900.0 0.1 511300.0 107000.0 0.77 0.6827 0.7053 474660.0 84320.157480315 0.566894874068948 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G02 mock treatment 419940.0 12200.0 0.08 369180.0 -35100.0 -0.25 -0.2332 -0.6309 384010.0 -6329.84251968499 -0.0425563161324837 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G03 mock treatment 460240.0 52500.0 0.35 425390.0 21100.0 0.15 0.4564 0.8718 398770.0 8430.15748031501 0.0566769940426199 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G04 mock treatment 498690.0 90900.0 0.61 476160.0 71800.0 0.52 0.7341 0.8685 404170.0 13830.157480315 0.0929818636188773 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G05 mock treatment 292590.0 -115000.0 -0.78 428030.0 23700.0 0.17 0.1219 0.1136 412120.0 21780.157480315 0.146430699383923 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G06 mock treatment 385450.0 -22300.0 -0.15 494730.0 90400.0 0.65 0.4963 0.5252 486400.0 96060.157480315 0.64582434977733 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G07 mock treatment 481650.0 73900.0 0.5 511490.0 107000.0 0.78 0.9838 0.881 483400.0 93060.157480315 0.62565497779052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G08 mock treatment 533120.0 125000.0 0.85 428160.0 23800.0 0.17 1.0915 0.9145 474760.0 84420.157480315 0.567567186468509 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G09 mock treatment 463910.0 56100.0 0.38 428760.0 24400.0 0.18 0.9942 0.9071 494880.0 104540.157480315 0.702836441260045 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G10 mock treatment 553600.0 146000.0 0.99 440800.0 36500.0 0.26 0.9993 0.8252 405980.0 15640.157480315 0.105150718050919 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G11 mock treatment 521210.0 113000.0 0.77 303550.0 -101000.0 -0.73 0.1165 0.0795 510720.0 120380.157480315 0.8093307253504 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G12 mock treatment 505760.0 98000.0 0.66 359590.0 -44700.0 -0.32 -0.1972 -0.2147 354840.0 -35499.842519685 -0.23866984308423 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G13 mock treatment 534560.0 127000.0 0.86 552920.0 149000.0 1.08 1.2609 0.873 449520.0 59180.157480315 0.397875536819483 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G14 mock treatment 427600.0 19800.0 0.13 459460.0 55100.0 0.4 0.6706 0.9431 445930.0 55590.157480315 0.373739521675268 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G15 mock treatment 500550.0 92800.0 0.63 493550.0 89200.0 0.65 0.7933 0.8527 405500.0 15160.157480315 0.10192361853303 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G16 mock treatment 469770.0 62000.0 0.42 470690.0 66400.0 0.48 0.5313 0.8202 402010.0 11670.157480315 0.0784599157883743 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G17 mock treatment 401770.0 -6000.0 -0.04 353280.0 -51000.0 -0.37 0.0257 0.0517 420000.0 29660.157480315 0.199408916469276 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G18 mock treatment 496900.0 89100.0 0.6 480280.0 76000.0 0.55 0.8124 0.8317 469790.0 79450.157480315 0.534153260210361 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G19 mock treatment 460560.0 52800.0 0.36 474660.0 70300.0 0.51 0.5902 0.8845 423940.0 33600.157480315 0.225898025011953 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G20 mock treatment 436690.0 28900.0 0.2 407570.0 3240.0 0.02 0.2219 0.8222 416930.0 26590.157480315 0.178768925802774 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G21 mock treatment 404330.0 -3440.0 -0.02 368240.0 -36100.0 -0.26 -0.2818 -0.8207 358980.0 -31359.842519685 -0.210836109742432 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G22 mock treatment 337650.0 -70100.0 -0.47 382330.0 -22000.0 -0.16 -0.4801 -0.8599 356390.0 -33949.842519685 -0.228249000891045 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G23 mock treatment 409620.0 1850.0 0.01 288750.0 -116000.0 -0.84 -0.1218 -0.1238 466750.0 76410.157480315 0.513714963263727 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base G24 mock treatment 398300.0 -9470.0 -0.06 303040.0 -101000.0 -0.73 -0.3939 -0.5208 372760.0 -17579.842519685 -0.11819146108302 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H01 mock treatment 448610.0 40800.0 0.28 384360.0 -20000.0 -0.14 -0.0708 -0.1672 392380.0 2040.15748031501 0.0137162317107153 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H02 mock treatment 516320.0 109000.0 0.73 282420.0 -122000.0 -0.88 0.1933 0.1317 517760.0 127420.157480315 0.856661518279447 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H03 mock treatment 414520.0 6750.0 0.05 476280.0 72000.0 0.52 -0.0485 -0.0356 464000.0 73660.157480315 0.495226372275818 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H04 mock treatment 351440.0 -56300.0 -0.38 436550.0 32200.0 0.23 -0.4664 -0.5684 289120.0 -101219.842519685 -0.680513552075273 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H05 mock treatment 476680.0 68900.0 0.47 383850.0 -20500.0 -0.15 0.8583 0.7695 477350.0 87010.157480315 0.584980077617121 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H06 mock treatment 529530.0 122000.0 0.82 500160.0 95800.0 0.69 0.6988 0.6118 342240.0 -48099.842519685 -0.32338120542883 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H07 mock treatment 555470.0 148000.0 1.0 428830.0 24500.0 0.18 1.388 0.901 482580.0 92240.157480315 0.620142016114126 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H08 mock treatment 534510.0 127000.0 0.86 370780.0 -33500.0 -0.24 0.2545 0.2825 370290.0 -20049.842519685 -0.13479757735216 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H09 mock treatment 424490.0 16700.0 0.11 476380.0 72100.0 0.52 0.1826 0.2889 399750.0 9410.15748031501 0.063265655558311 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H10 mock treatment 464280.0 56500.0 0.38 293360.0 -111000.0 -0.8 0.1683 0.1618 439680.0 49340.157480315 0.331719996702748 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H11 mock treatment 358140.0 -49600.0 -0.34 423450.0 19100.0 0.14 0.052 0.0925 373510.0 -16829.842519685 -0.113149118086318 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H12 mock treatment 383520.0 -24300.0 -0.16 499840.0 95500.0 0.69 0.1625 0.1963 417390.0 27050.157480315 0.181861562840752 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H13 mock treatment 486810.0 79000.0 0.53 514450.0 110000.0 0.8 1.182 0.9732 482490.0 92150.157480315 0.619536934954521 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H14 mock treatment 379260.0 -28500.0 -0.19 304970.0 -99400.0 -0.72 0.1735 0.1492 491230.0 100890.157480315 0.678297038676094 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H15 mock treatment 460380.0 52600.0 0.36 484020.0 79700.0 0.58 0.9441 0.9672 441240.0 50900.157480315 0.342208070135889 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H16 mock treatment 531920.0 124000.0 0.84 520890.0 117000.0 0.84 1.226 0.9331 434880.0 44540.157480315 0.299449001523852 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H17 mock treatment 483360.0 75600.0 0.51 399490.0 -4840.0 -0.04 0.7297 0.7809 425970.0 35630.157480315 0.239545966723027 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H18 mock treatment 445800.0 38000.0 0.26 444590.0 40300.0 0.29 0.4674 0.978 424660.0 34320.157480315 0.230738674288787 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H19 mock treatment 414210.0 6440.0 0.04 352380.0 -51900.0 -0.38 0.6683 0.5318 536240.0 145900.157480315 0.980904849718195 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H20 mock treatment 489520.0 81700.0 0.55 423080.0 18800.0 0.14 0.5439 0.5239 333700.0 -56639.842519685 -0.380796684351282 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H21 mock treatment 279440.0 -128000.0 -0.87 297960.0 -106000.0 -0.77 -0.6246 -0.5236 413360.0 23020.157480315 0.154767373138471 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H22 mock treatment 354040.0 -53700.0 -0.36 439040.0 34700.0 0.25 -0.1979 -0.3071 324610.0 -65729.842519685 -0.441909881471315 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H23 mock treatment 322760.0 -85000.0 -0.57 430880.0 26600.0 0.19 0.2882 0.3165 455920.0 65580.157480315 0.440903530391344 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base H24 mock treatment 285860.0 -122000.0 -0.82 351550.0 -52800.0 -0.38 -0.7434 -0.7495 333040.0 -57299.842519685 -0.38523394618838 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I01 mock treatment 467530.0 59800.0 0.4 374930.0 -29400.0 -0.21 -0.2054 -0.2749 388800.0 -1539.84251968499 -0.0103525521935443 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I02 mock treatment 516830.0 109000.0 0.74 450100.0 45800.0 0.33 0.6194 0.73 378880.0 -11459.842519685 -0.0770459422299282 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I03 mock treatment 346110.0 -61700.0 -0.42 503120.0 98800.0 0.72 -0.0806 -0.0904 363360.0 -26979.842519685 -0.18138882664169 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I04 mock treatment 374200.0 -33600.0 -0.23 479220.0 74900.0 0.54 0.3346 0.3986 359360.0 -30979.842519685 -0.208281322624103 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I05 mock treatment 427360.0 19600.0 0.13 537600.0 133000.0 0.96 0.3423 0.3351 349310.0 -41029.842519685 -0.275848718779915 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I06 mock treatment 503240.0 95500.0 0.65 460360.0 56000.0 0.41 0.6587 0.5782 497030.0 106690.157480315 0.717291157850592 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I07 mock treatment 572740.0 165000.0 1.11 559810.0 155000.0 1.13 1.4286 0.8695 435360.0 45020.157480315 0.302676101041742 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I08 mock treatment 486900.0 79100.0 0.53 295110.0 -109000.0 -0.79 -0.0219 -0.0225 393440.0 3100.15748031501 0.0208427431460547 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I09 mock treatment 536550.0 129000.0 0.87 445780.0 41500.0 0.3 0.1291 0.1121 349080.0 -41259.842519685 -0.277395037298904 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I10 mock treatment 508080.0 100000.0 0.68 491210.0 86900.0 0.63 1.165 0.931 420920.0 30580.157480315 0.205594190545231 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I11 mock treatment 470100.0 62300.0 0.42 526760.0 122000.0 0.89 -0.0564 -0.0401 292900.0 -97439.842519685 -0.655100143371893 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I12 mock treatment 288680.0 -119000.0 -0.8 509520.0 105000.0 0.76 -0.349 -0.2261 239600.0 -150739.842519685 -1.01344265233754 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I13 mock treatment 558590.0 151000.0 1.02 443370.0 39000.0 0.28 0.8048 0.6792 361920.0 -28419.842519685 -0.191070125195359 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I14 mock treatment 482670.0 74900.0 0.51 532100.0 128000.0 0.92 1.4353 0.957 530920.0 140580.157480315 0.945137830061585 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I15 mock treatment 540960.0 133000.0 0.9 452260.0 47900.0 0.35 1.0048 0.9077 453840.0 63500.157480315 0.426919432480489 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I16 mock treatment 488530.0 80800.0 0.55 500690.0 96400.0 0.7 0.6682 0.6127 463850.0 73510.157480315 0.494217903676477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I17 mock treatment 472170.0 64400.0 0.44 480220.0 75900.0 0.55 0.3344 0.4502 377820.0 -12519.842519685 -0.0841724536652676 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I18 mock treatment 503580.0 95800.0 0.65 485190.0 80900.0 0.59 0.7259 0.7969 384560.0 -5779.84251968499 -0.0388585979349019 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I19 mock treatment 443770.0 36000.0 0.24 457880.0 53600.0 0.39 0.7133 0.9478 470630.0 80290.157480315 0.539800684366667 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I20 mock treatment 435710.0 27900.0 0.19 512110.0 108000.0 0.78 0.5579 0.5672 342480.0 -47859.842519685 -0.321767655669885 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I21 mock treatment 390500.0 -17300.0 -0.12 371000.0 -33300.0 -0.24 -0.3511 -0.8645 384090.0 -6249.84251968499 -0.0420184662128354 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I22 mock treatment 357550.0 -50200.0 -0.34 490750.0 86400.0 0.63 -0.2051 -0.2369 340410.0 -49929.842519685 -0.335684522340784 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I23 mock treatment 309150.0 -98600.0 -0.67 345390.0 -58900.0 -0.43 -0.8215 -0.835 395360.0 5020.15748031501 0.0337511412176129 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base I24 mock treatment 380320.0 -27500.0 -0.19 386100.0 -18200.0 -0.13 0.0116 0.0231 455200.0 64860.157480315 0.43606288111451 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J01 mock treatment 357330.0 -50400.0 -0.34 275490.0 -129000.0 -0.93 -1.3296 -0.953 285830.0 -104509.842519685 -0.702632630020808 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J02 mock treatment 342400.0 -65400.0 -0.44 308230.0 -96100.0 -0.7 -0.8283 -0.8004 298420.0 -91919.842519685 -0.617988498916163 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J03 mock treatment 310960.0 -96800.0 -0.65 343940.0 -60400.0 -0.44 -1.2515 -0.9805 272980.0 -117359.842519685 -0.789024773364309 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J04 mock treatment 415800.0 8030.0 0.05 435680.0 31400.0 0.23 -0.163 -0.2052 411080.0 20740.157480315 0.139438650428496 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J05 mock treatment 347700.0 -60100.0 -0.41 459420.0 55100.0 0.4 -0.5185 -0.54 341140.0 -49199.842519685 -0.330776641823994 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J06 mock treatment 225200.0 -183000.0 -1.23 338840.0 -65500.0 -0.47 -0.8521 -0.6214 429090.0 38750.157480315 0.260522113589309 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J07 mock treatment 321090.0 -86700.0 -0.59 480380.0 76100.0 0.55 -0.3434 -0.2358 460060.0 69720.157480315 0.468737263733141 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J08 mock treatment 280450.0 -127000.0 -0.86 317470.0 -86900.0 -0.63 -0.2189 -0.1563 523380.0 133040.157480315 0.894445475134737 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J09 mock treatment 378790.0 -29000.0 -0.2 437730.0 33400.0 0.24 0.1002 0.2915 391640.0 1300.15748031501 0.00874111995396889 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J10 mock treatment 452290.0 44500.0 0.3 373380.0 -30900.0 -0.22 0.1105 0.1917 445880.0 55540.157480315 0.373403365475488 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J11 mock treatment 431710.0 23900.0 0.16 422050.0 17700.0 0.13 -0.0903 -0.2225 366560.0 -23779.842519685 -0.15987482985576 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J12 mock treatment 398770.0 -9000.0 -0.06 558200.0 154000.0 1.11 -0.8207 -0.3716 185210.0 -205129.842519685 -1.3791133664584 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J13 mock treatment 505690.0 97900.0 0.66 391450.0 -12900.0 -0.09 0.8824 0.8031 501660.0 111320.157480315 0.748419221950235 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J14 mock treatment 456820.0 49000.0 0.33 441630.0 37300.0 0.27 0.3881 0.4493 325460.0 -64879.842519685 -0.436195226075052 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J15 mock treatment 464840.0 57100.0 0.39 451360.0 47000.0 0.34 0.9251 0.955 452440.0 62100.157480315 0.417507058886645 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J16 mock treatment 369090.0 -38700.0 -0.26 340850.0 -63500.0 -0.46 -0.0593 -0.079 401250.0 10910.157480315 0.0733503415517158 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J17 mock treatment 471840.0 64100.0 0.43 444050.0 39700.0 0.29 0.9598 0.9296 450350.0 60010.157480315 0.403455729735834 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J18 mock treatment 478490.0 70700.0 0.48 403320.0 -1010.0 -0.01 0.5261 0.5434 510880.0 120540.157480315 0.810406425189697 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J19 mock treatment 488030.0 80300.0 0.54 482490.0 78200.0 0.57 0.6954 0.8441 394890.0 4550.15748031501 0.0305912729396794 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J20 mock treatment 369620.0 -38200.0 -0.26 387490.0 -16800.0 -0.12 0.0496 0.0869 388020.0 -2319.84251968499 -0.0155965889101148 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J21 mock treatment 252870.0 -155000.0 -1.05 291490.0 -113000.0 -0.82 -0.7297 -0.5126 375460.0 -14879.842519685 -0.100039026294891 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J22 mock treatment 315420.0 -92400.0 -0.62 343370.0 -61000.0 -0.44 -0.6433 -0.4599 251750.0 -138589.842519685 -0.931756695790966 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J23 mock treatment 244320.0 -163000.0 -1.1 404520.0 190.0 0.0 -0.9733 -0.7303 280510.0 -109829.842519685 -0.738399649677417 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base J24 mock treatment 320900.0 -86900.0 -0.59 284810.0 -120000.0 -0.87 -0.9436 -0.654 258520.0 -131819.842519685 -0.886241146340732 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K01 mock treatment 335130.0 -72600.0 -0.49 450490.0 46200.0 0.33 0.1548 0.1966 383080.0 -7259.84251968499 -0.0488088214483947 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K02 mock treatment 392160.0 -15600.0 -0.11 367210.0 -37100.0 -0.27 0.0418 0.0529 354790.0 -35549.842519685 -0.23900599928401 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K03 mock treatment 278780.0 -129000.0 -0.87 516580.0 112000.0 0.81 0.8801 0.4823 472530.0 82190.157480315 0.552574619958313 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K04 mock treatment 428480.0 20700.0 0.14 446290.0 42000.0 0.3 1.0821 0.8461 540290.0 149950.157480315 1.00813350190039 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K05 mock treatment 480370.0 72600.0 0.49 429450.0 25100.0 0.18 0.3889 0.2647 542410.0 152070.157480315 1.02238652477107 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K06 mock treatment 264770.0 -143000.0 -0.97 454650.0 50300.0 0.36 -0.0105 -0.0071 537860.0 147520.157480315 0.991796310591072 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K07 mock treatment 425370.0 17600.0 0.12 548390.0 144000.0 1.04 0.2033 0.1634 376360.0 -13979.842519685 -0.0939882146988483 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K08 mock treatment 354240.0 -53500.0 -0.36 535580.0 131000.0 0.95 -0.2058 -0.1563 363160.0 -27179.842519685 -0.182733451440811 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K09 mock treatment 431450.0 23700.0 0.16 407460.0 3130.0 0.02 -0.1276 -0.2268 311410.0 -78929.842519685 -0.530655118213277 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K10 mock treatment 367360.0 -40400.0 -0.27 300880.0 -103000.0 -0.75 -0.1971 -0.2064 407310.0 16970.157480315 0.114092472965071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K11 mock treatment 452030.0 44300.0 0.3 447010.0 42700.0 0.31 0.373 0.5339 457600.0 67260.157480315 0.452198378703957 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K12 mock treatment 400480.0 -7290.0 -0.05 355930.0 -48400.0 -0.35 -0.5973 -0.8845 318410.0 -71929.842519685 -0.483593250244055 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K13 mock treatment 631910.0 224000.0 1.51 455410.0 51100.0 0.37 1.3107 0.7815 410090.0 19750.157480315 0.132782757672848 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K14 mock treatment 515520.0 108000.0 0.73 433760.0 29400.0 0.21 0.4876 0.6032 422130.0 31790.157480315 0.213729170579911 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K15 mock treatment 470520.0 62700.0 0.42 562840.0 159000.0 1.15 1.3985 0.8657 418160.0 27820.157480315 0.187038368317366 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K16 mock treatment 529440.0 122000.0 0.82 448540.0 44200.0 0.32 0.7181 0.7607 439960.0 49620.157480315 0.333602471421517 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K17 mock treatment 465820.0 58000.0 0.39 328180.0 -76100.0 -0.55 0.4764 0.4329 511730.0 121390.157480315 0.81612108058596 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K18 mock treatment 395150.0 -12600.0 -0.09 494830.0 90500.0 0.66 0.33 0.4972 397790.0 7450.15748031501 0.0500883325269287 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K19 mock treatment 373720.0 -34100.0 -0.23 497130.0 92800.0 0.67 0.6733 0.5496 538240.0 147900.157480315 0.994351097709401 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K20 mock treatment 435650.0 27900.0 0.19 349040.0 -55300.0 -0.4 0.0949 0.1433 462610.0 72270.157480315 0.485881229921929 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K21 mock treatment 329530.0 -78200.0 -0.53 287700.0 -117000.0 -0.84 -0.4776 -0.4423 452280.0 61940.157480315 0.416431359047348 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K22 mock treatment 327870.0 -79900.0 -0.54 512450.0 108000.0 0.78 0.7711 0.5784 469040.0 78700.157480315 0.529110917213658 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K23 mock treatment 276770.0 -131000.0 -0.89 460520.0 56200.0 0.41 -0.0637 -0.0597 378730.0 -11609.842519685 -0.0780544108292687 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base K24 mock treatment 357470.0 -50300.0 -0.34 497710.0 93400.0 0.68 0.249 0.2132 309620.0 -80719.842519685 -0.542689510165407 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L01 mock treatment 207200.0 -201000.0 -1.36 315230.0 -89100.0 -0.64 -1.486 -0.8997 323720.0 -66619.842519685 -0.447893461827402 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L02 mock treatment 471300.0 63500.0 0.43 507230.0 103000.0 0.74 -0.2924 -0.1793 323810.0 -66529.842519685 -0.447288380667798 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L03 mock treatment 208830.0 -199000.0 -1.34 325860.0 -78500.0 -0.57 -0.8683 -0.5648 354200.0 -36139.842519685 -0.242972642441416 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L04 mock treatment 446720.0 38900.0 0.26 301040.0 -103000.0 -0.75 -0.1097 -0.129 435700.0 45360.157480315 0.304961963200247 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L05 mock treatment 447770.0 40000.0 0.27 537180.0 133000.0 0.96 0.7954 0.7668 404730.0 14390.157480315 0.0967468130564151 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L06 mock treatment 366260.0 -41500.0 -0.28 512280.0 108000.0 0.78 -0.1327 -0.085 460160.0 69820.157480315 0.469409576132702 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L07 mock treatment 349240.0 -58500.0 -0.4 256480.0 -148000.0 -1.07 -0.2891 -0.1634 582360.0 192020.157480315 1.29097532839542 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L08 mock treatment 424660.0 16900.0 0.11 262890.0 -141000.0 -1.02 -0.2047 -0.1496 514650.0 124310.157480315 0.835752602653121 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L09 mock treatment 294250.0 -114000.0 -0.77 345140.0 -59200.0 -0.43 -0.4328 -0.3715 338250.0 -52089.842519685 -0.350206470171287 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L10 mock treatment 459480.0 51700.0 0.35 429280.0 25000.0 0.18 0.8007 0.9312 459150.0 68810.157480315 0.462619220897142 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L11 mock treatment 558290.0 151000.0 1.02 456590.0 52300.0 0.38 -0.0136 -0.009 314520.0 -75819.842519685 -0.509746202586951 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L12 mock treatment 482730.0 75000.0 0.51 499220.0 94900.0 0.69 0.2417 0.2261 380000.0 -10339.842519685 -0.0695160433548526 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L13 mock treatment 472580.0 64800.0 0.44 480820.0 76500.0 0.55 0.8403 0.8439 494780.0 104440.157480315 0.702164128860485 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L14 mock treatment 497500.0 89700.0 0.61 472960.0 68600.0 0.5 0.506 0.6157 358480.0 -31859.842519685 -0.214197671740234 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L15 mock treatment 601560.0 194000.0 1.31 467720.0 63400.0 0.46 0.8119 0.4344 248320.0 -142019.842519685 -0.954817011095885 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L16 mock treatment 518630.0 111000.0 0.75 490040.0 85700.0 0.62 0.7844 0.7981 406570.0 16230.157480315 0.109117361208325 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L17 mock treatment 548830.0 141000.0 0.95 515000.0 111000.0 0.8 1.0519 0.7168 338900.0 -51439.842519685 -0.345836439574145 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L18 mock treatment 474820.0 67000.0 0.45 546490.0 142000.0 1.03 1.1931 0.9125 477660.0 87320.157480315 0.587064246055758 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L19 mock treatment 534000.0 126000.0 0.85 490570.0 86200.0 0.62 1.0257 0.8297 380870.0 -9469.84251968499 -0.0636669254786778 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L20 mock treatment 291800.0 -116000.0 -0.78 458450.0 54100.0 0.39 -0.1398 -0.1564 415470.0 25130.157480315 0.168953164769194 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L21 mock treatment 430940.0 23200.0 0.16 494880.0 90600.0 0.66 1.0765 0.9238 497190.0 106850.157480315 0.718366857689889 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L22 mock treatment 308440.0 -99300.0 -0.67 483530.0 79200.0 0.57 0.3582 0.3191 410210.0 19870.157480315 0.133589532552321 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L23 mock treatment 411040.0 3270.0 0.02 415520.0 11200.0 0.08 0.3448 0.7272 456450.0 66110.157480315 0.444466786109014 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base L24 mock treatment 402520.0 -5250.0 -0.04 400390.0 -3940.0 -0.03 -0.0807 -0.103 301150.0 -89189.842519685 -0.599634370408167 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M01 mock treatment 356600.0 -51200.0 -0.35 356960.0 -47400.0 -0.34 -0.4111 -0.361 488230.0 97890.157480315 0.658127666689284 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M02 mock treatment 344440.0 -63300.0 -0.43 293980.0 -110000.0 -0.8 -1.2178 -0.9239 345730.0 -44609.842519685 -0.299917502684175 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M03 mock treatment 486410.0 78600.0 0.53 386950.0 -17400.0 -0.13 0.8082 0.765 449760.0 59420.157480315 0.399489086578428 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M04 mock treatment 486580.0 78800.0 0.53 536190.0 132000.0 0.95 1.6578 0.9593 562800.0 172460.157480315 1.15947102304142 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M05 mock treatment 492040.0 84300.0 0.57 417310.0 13000.0 0.09 1.0037 0.8935 507150.0 116810.157480315 0.785329172686097 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M06 mock treatment 518740.0 111000.0 0.75 372090.0 -32200.0 -0.23 0.1536 0.1157 486310.0 95970.157480315 0.645219268617726 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M07 mock treatment 546990.0 139000.0 0.94 292160.0 -112000.0 -0.81 0.6159 0.3859 538410.0 148070.157480315 0.995494028788654 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M08 mock treatment 394980.0 -12800.0 -0.09 308210.0 -96100.0 -0.7 -0.7726 -0.6454 248770.0 -141569.842519685 -0.951791605297863 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M09 mock treatment 493620.0 85800.0 0.58 408320.0 3990.0 0.03 0.2917 0.3378 455630.0 65290.157480315 0.438953824432619 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M10 mock treatment 552410.0 145000.0 0.98 554240.0 150000.0 1.09 1.9437 0.9973 524130.0 133790.157480315 0.89948781813144 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M11 mock treatment 544270.0 136000.0 0.92 478420.0 74100.0 0.54 1.5704 0.9823 520900.0 130560.157480315 0.877772127625641 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M12 mock treatment 402490.0 -5280.0 -0.04 300730.0 -104000.0 -0.75 -0.7191 -0.641 268800.0 -121539.842519685 -0.817127431665931 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M13 mock treatment 568920.0 161000.0 1.09 493470.0 89100.0 0.65 1.4928 0.9465 449760.0 59420.157480315 0.399489086578428 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M14 mock treatment 457510.0 49700.0 0.34 398440.0 -5890.0 -0.04 0.9435 0.7622 468430.0 78090.157480315 0.52500981157634 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M15 mock treatment 485500.0 77700.0 0.53 474050.0 69700.0 0.5 1.1138 0.9688 450810.0 60470.157480315 0.406548366773811 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M16 mock treatment 547130.0 139000.0 0.94 515220.0 111000.0 0.8 1.2822 0.9295 471200.0 80860.157480315 0.543632865044161 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M17 mock treatment 505990.0 98200.0 0.66 471070.0 66700.0 0.48 1.1304 0.892 531910.0 141570.157480315 0.951793722817233 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M18 mock treatment 494980.0 87200.0 0.59 502110.0 97800.0 0.71 0.7645 0.6507 332820.0 -57519.842519685 -0.386713033467413 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M19 mock treatment 385160.0 -22600.0 -0.15 372700.0 -31600.0 -0.23 0.1567 0.2776 445950.0 55610.157480315 0.37387398415518 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M20 mock treatment 444340.0 36600.0 0.25 404200.0 -130.0 0.0 0.3882 0.4192 344590.0 -45749.842519685 -0.307581864039163 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M21 mock treatment 458420.0 50600.0 0.34 473050.0 68700.0 0.5 0.8554 0.9446 484110.0 93770.157480315 0.630428395827399 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M22 mock treatment 323100.0 -84700.0 -0.57 343640.0 -60700.0 -0.44 -0.0036 -0.0036 474580.0 84240.157480315 0.5663570241493 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M23 mock treatment 353450.0 -54300.0 -0.37 328610.0 -75700.0 -0.55 0.0429 0.0438 448370.0 58030.157480315 0.39014394422454 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base M24 mock treatment 409150.0 1380.0 0.01 375410.0 -28900.0 -0.21 -0.2076 -0.674 391880.0 1540.15748031501 0.0103546697129137 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N01 mock treatment 437930.0 30200.0 0.2 310280.0 -94000.0 -0.68 0.0668 0.0769 462100.0 71760.157480315 0.482452436684172 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N02 mock treatment 481920.0 74100.0 0.5 489950.0 85600.0 0.62 0.6949 0.8476 407200.0 16860.157480315 0.113352929325555 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N03 mock treatment 470270.0 62500.0 0.42 155010.0 -249000.0 -1.8 -0.9393 -0.4713 421070.0 30730.157480315 0.206602659144572 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N04 mock treatment 504520.0 96700.0 0.65 212500.0 -192000.0 -1.39 0.3591 0.1931 476070.0 85730.157480315 0.576374478902749 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N05 mock treatment 519650.0 112000.0 0.76 313040.0 -91300.0 -0.66 0.1074 0.0727 512880.0 122540.157480315 0.823852673180903 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N06 mock treatment 543680.0 136000.0 0.92 408100.0 3770.0 0.03 0.4539 0.4401 338320.0 -52019.842519685 -0.349735851491595 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N07 mock treatment 339520.0 -68300.0 -0.46 373890.0 -30400.0 -0.22 -0.5381 -0.572 438690.0 48350.157480315 0.3250641039471 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N08 mock treatment 538730.0 131000.0 0.88 325990.0 -78300.0 -0.57 0.5849 0.4755 476270.0 85930.157480315 0.57771910370187 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N09 mock treatment 402560.0 -5210.0 -0.04 494560.0 90200.0 0.65 0.1181 0.097 257760.0 -132579.842519685 -0.89135072057739 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N10 mock treatment 450950.0 43200.0 0.29 303720.0 -101000.0 -0.73 0.2288 0.1862 382890.0 -7449.84251968499 -0.0500862150075593 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N11 mock treatment 372330.0 -35400.0 -0.24 391470.0 -12900.0 -0.09 -0.339 -0.542 310460.0 -79879.842519685 -0.537042086009101 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N12 mock treatment 405140.0 -2630.0 -0.02 538420.0 134000.0 0.97 0.5433 0.4053 496970.0 106630.157480315 0.716887770410856 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N13 mock treatment 426590.0 18800.0 0.13 407490.0 3160.0 0.02 -0.1321 -0.2261 410930.0 20590.157480315 0.138430181829155 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N14 mock treatment 455310.0 47500.0 0.32 427610.0 23300.0 0.17 0.2753 0.4594 444830.0 54490.157480315 0.366344085280104 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N15 mock treatment 523600.0 116000.0 0.78 496080.0 91800.0 0.66 0.4502 0.4003 323580.0 -66759.842519685 -0.448834699186786 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N16 mock treatment 363310.0 -44500.0 -0.3 456240.0 51900.0 0.38 0.1682 0.3081 428730.0 38390.157480315 0.258101788950892 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N17 mock treatment 484730.0 77000.0 0.52 337800.0 -66500.0 -0.48 0.346 0.3719 479650.0 89310.157480315 0.600443262807008 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N18 mock treatment 511220.0 103000.0 0.7 465300.0 61000.0 0.44 0.8224 0.9004 444050.0 53710.157480315 0.361100048563534 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N19 mock treatment 390770.0 -17000.0 -0.11 436850.0 32500.0 0.24 0.0747 0.1444 345600.0 -44739.842519685 -0.300791508803603 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N20 mock treatment 317830.0 -89900.0 -0.61 502740.0 98400.0 0.71 -0.1497 -0.1511 376160.0 -14179.842519685 -0.095332839497969 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N21 mock treatment 290590.0 -117000.0 -0.79 291040.0 -113000.0 -0.82 -0.6241 -0.5247 393980.0 3640.15748031501 0.0244732301036804 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N22 mock treatment 366560.0 -41200.0 -0.28 375480.0 -28800.0 -0.21 -0.2976 -0.7997 371010.0 -19329.842519685 -0.129956928075326 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N23 mock treatment 284830.0 -123000.0 -0.83 302480.0 -102000.0 -0.74 -0.7184 -0.635 420570.0 30230.157480315 0.20324109714677 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base N24 mock treatment 227200.0 -181000.0 -1.22 454590.0 50300.0 0.36 -0.739 -0.5377 372840.0 -17499.842519685 -0.117653611163372 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O01 mock treatment 296250.0 -112000.0 -0.75 400880.0 -3450.0 -0.02 -1.3873 -0.8512 209350.0 -180989.842519685 -1.21681715320454 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O02 mock treatment 441920.0 34100.0 0.23 452200.0 47900.0 0.35 -0.0331 -0.0251 220160.0 -170179.842519685 -1.14414018281207 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O03 mock treatment 428820.0 21000.0 0.14 308980.0 -95300.0 -0.69 -0.6405 -0.6839 300660.0 -89679.842519685 -0.602928701166012 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O04 mock treatment 456640.0 48900.0 0.33 362140.0 -42200.0 -0.31 -0.4 -0.4939 364430.0 -25909.842519685 -0.174195083966395 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O05 mock treatment 282730.0 -125000.0 -0.84 424290.0 20000.0 0.14 -0.6234 -0.6569 363220.0 -27119.842519685 -0.182330064001075 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O06 mock treatment 389050.0 -18700.0 -0.13 361810.0 -42500.0 -0.31 -0.7759 -0.8785 284930.0 -105409.842519685 -0.708683441616851 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O07 mock treatment 355890.0 -51900.0 -0.35 270020.0 -134000.0 -0.97 -0.8315 -0.7659 389140.0 -1199.84251968499 -0.00806669003503916 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O08 mock treatment 295050.0 -113000.0 -0.76 383240.0 -21100.0 -0.15 -0.7226 -0.6862 287360.0 -102979.842519685 -0.692346250307535 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O09 mock treatment 260430.0 -147000.0 -1.0 420600.0 16300.0 0.12 -0.9771 -0.7734 321730.0 -68609.842519685 -0.461272478578652 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O10 mock treatment 319860.0 -87900.0 -0.59 272750.0 -132000.0 -0.95 -0.6775 -0.542 460640.0 70300.157480315 0.472636675650591 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O11 mock treatment 380160.0 -27600.0 -0.19 461250.0 56900.0 0.41 -0.2162 -0.2951 305650.0 -84689.842519685 -0.569380312427952 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O12 mock treatment 308480.0 -99300.0 -0.67 405150.0 820.0 0.01 -0.9829 -0.8524 312830.0 -77509.842519685 -0.521108282139521 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O13 mock treatment 419320.0 11500.0 0.08 366490.0 -37800.0 -0.27 0.1804 0.3548 415970.0 25630.157480315 0.172314726766995 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O14 mock treatment 430850.0 23100.0 0.16 430500.0 26200.0 0.19 0.5029 0.7823 478090.0 87750.157480315 0.589955189373867 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O15 mock treatment 307330.0 -100000.0 -0.68 299040.0 -105000.0 -0.76 -0.7771 -0.751 397770.0 7430.15748031501 0.0499538700470166 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O16 mock treatment 358240.0 -49500.0 -0.33 367120.0 -37200.0 -0.27 -0.2907 -0.4575 441240.0 50900.157480315 0.342208070135889 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O17 mock treatment 387780.0 -20000.0 -0.14 401230.0 -3100.0 -0.02 0.0688 0.1693 378570.0 -11769.842519685 -0.0791301106685652 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O18 mock treatment 388420.0 -19400.0 -0.13 332750.0 -71600.0 -0.52 -0.2786 -0.355 457210.0 66870.157480315 0.449576360345672 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O19 mock treatment 299730.0 -108000.0 -0.73 255940.0 -148000.0 -1.07 -1.2197 -0.8816 359970.0 -30369.842519685 -0.204180216986785 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O20 mock treatment 376480.0 -31300.0 -0.21 361860.0 -42500.0 -0.31 -0.3943 -0.5255 435740.0 45400.157480315 0.305230888160071 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O21 mock treatment 394500.0 -13300.0 -0.09 306080.0 -98200.0 -0.71 -0.7936 -0.8641 316840.0 -73499.842519685 -0.494148554917152 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O22 mock treatment 327310.0 -80500.0 -0.54 283100.0 -121000.0 -0.88 -0.7626 -0.6384 319860.0 -70479.842519685 -0.47384472045043 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O23 mock treatment 276520.0 -131000.0 -0.89 344430.0 -59900.0 -0.43 -0.4881 -0.4454 372930.0 -17409.842519685 -0.117048530003767 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base O24 mock treatment 365340.0 -42400.0 -0.29 350750.0 -53600.0 -0.39 -0.9812 -0.952 292360.0 -97979.842519685 -0.658730630329519 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P01 mock treatment 338820.0 -69000.0 -0.47 368910.0 -35400.0 -0.26 -1.0521 -0.9319 267360.0 -122979.842519685 -0.826808730219599 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P02 mock treatment 246890.0 -161000.0 -1.09 349290.0 -55000.0 -0.4 -1.5483 -0.947 250940.0 -139399.842519685 -0.937202426227404 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P03 mock treatment 242770.0 -165000.0 -1.11 245920.0 -158000.0 -1.15 -2.0275 -0.9563 196640.0 -193699.842519685 -1.30226805918866 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P04 mock treatment 300450.0 -107000.0 -0.73 221980.0 -182000.0 -1.32 -2.0907 -0.9797 224910.0 -165429.842519685 -1.11220534383296 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P05 mock treatment 274910.0 -133000.0 -0.9 330290.0 -74000.0 -0.54 -2.0237 -0.9509 181050.0 -209289.842519685 -1.40708156228011 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P06 mock treatment 239140.0 -169000.0 -1.14 261380.0 -143000.0 -1.03 -1.9413 -0.9904 275520.0 -114819.842519685 -0.771948038415477 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P07 mock treatment 280960.0 -127000.0 -0.86 215200.0 -189000.0 -1.37 -2.0659 -0.9812 258370.0 -131969.842519685 -0.887249614940072 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P08 mock treatment 235570.0 -172000.0 -1.16 238120.0 -166000.0 -1.2 -2.3539 -0.9977 199680.0 -190659.842519685 -1.28182976224203 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P09 mock treatment 272480.0 -135000.0 -0.91 260750.0 -144000.0 -1.04 -1.9598 -0.9989 241040.0 -149299.842519685 -1.00376135378388 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P10 mock treatment 231320.0 -176000.0 -1.19 250800.0 -154000.0 -1.11 -1.7824 -0.9528 319550.0 -70789.842519685 -0.475928888889067 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P11 mock treatment 248900.0 -159000.0 -1.07 240970.0 -163000.0 -1.18 -2.2961 -0.9949 193870.0 -196469.842519685 -1.32089111265648 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P12 mock treatment 264410.0 -143000.0 -0.97 248530.0 -156000.0 -1.13 -1.7895 -0.9799 263140.0 -127199.842519685 -0.855180313481045 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P13 mock treatment 241920.0 -166000.0 -1.12 238500.0 -166000.0 -1.2 -1.9251 -0.9762 292410.0 -97929.842519685 -0.658394474129739 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P14 mock treatment 272840.0 -135000.0 -0.91 308880.0 -95400.0 -0.69 -1.7411 -0.9917 241490.0 -148849.842519685 -1.00073594798585 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P15 mock treatment 255050.0 -153000.0 -1.03 221340.0 -183000.0 -1.32 -2.1487 -0.9825 275680.0 -114659.842519685 -0.770872338576181 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P16 mock treatment 259220.0 -149000.0 -1.0 255200.0 -149000.0 -1.08 -1.8359 -0.9807 300040.0 -90299.842519685 -0.607097038043286 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P17 mock treatment 276040.0 -132000.0 -0.89 235150.0 -169000.0 -1.22 -1.947 -0.9871 244850.0 -145489.842519685 -0.978146251360628 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P18 mock treatment 262810.0 -145000.0 -0.98 247540.0 -157000.0 -1.13 -1.9662 -0.9907 234350.0 -155989.842519685 -1.04873905331446 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P19 mock treatment 245880.0 -162000.0 -1.09 241150.0 -163000.0 -1.18 -1.8587 -0.967 256760.0 -133579.842519685 -0.898073844572994 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P20 mock treatment 227080.0 -181000.0 -1.22 235380.0 -169000.0 -1.22 -1.8728 -0.9527 311920.0 -78419.842519685 -0.52722632497552 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P21 mock treatment 242980.0 -165000.0 -1.11 240650.0 -164000.0 -1.18 -1.795 -0.9519 264880.0 -125459.842519685 -0.843482077728695 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P22 mock treatment 230840.0 -177000.0 -1.2 258770.0 -146000.0 -1.05 -2.255 -0.9976 209440.0 -180899.842519685 -1.21621207204494 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P23 mock treatment 214610.0 -193000.0 -1.31 190150.0 -214000.0 -1.55 -2.5178 -0.9888 230190.0 -160149.842519685 -1.07670724913617 1001.0075 CellTiterGlo(1001.0075) MODYPatientCellProfiling 1001.0075.Base P24 mock treatment 166950.0 -241000.0 -1.63 201760.0 -203000.0 -1.47 -2.6762 -0.9849 203120.0 -187219.842519685 -1.25870221569715