ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A01 compound treatment 192600.0 -216000.0 -2.19 208890.0 -185000.0 -1.94 -2.921 -0.9981 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A02 compound treatment 185050.0 -223000.0 -2.27 164170.0 -230000.0 -2.41 -3.3066 -0.9996 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A03 compound treatment 331380.0 -76900.0 -0.78 277890.0 -116000.0 -1.22 -1.4125 -0.9771 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A04 compound treatment 348560.0 -59700.0 -0.61 367720.0 -26300.0 -0.28 -0.6236 -0.9362 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A05 compound treatment 295490.0 -113000.0 -1.15 258770.0 -135000.0 -1.42 -1.8121 -0.9945 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A06 compound treatment 231390.0 -177000.0 -1.8 227680.0 -166000.0 -1.74 -2.503 -0.9999 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A07 compound treatment 177140.0 -231000.0 -2.35 206940.0 -187000.0 -1.96 -3.0465 -0.996 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A08 compound treatment 318330.0 -89900.0 -0.91 396890.0 2890.0 0.03 -0.6247 -0.6833 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A09 compound treatment 326880.0 -81400.0 -0.83 255300.0 -139000.0 -1.45 -1.6122 -0.9643 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A10 compound treatment 216430.0 -192000.0 -1.95 250400.0 -144000.0 -1.5 -2.4422 -0.9918 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A11 compound treatment 372370.0 -35900.0 -0.36 315920.0 -78100.0 -0.82 -0.8363 -0.9337 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A12 compound treatment 317930.0 -90300.0 -0.92 292860.0 -101000.0 -1.06 -1.3983 -0.9974 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A13 mock treatment 356570.0 -51700.0 -0.53 374440.0 -19600.0 -0.2 -0.5162 -0.9158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A14 mock treatment 409280.0 1040.0 0.01 423680.0 29700.0 0.31 0.2273 0.7306 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A15 compound treatment 216220.0 -192000.0 -1.95 222520.0 -171000.0 -1.8 -2.6503 -0.9991 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A16 compound treatment 283380.0 -125000.0 -1.27 292580.0 -101000.0 -1.06 -1.6486 -0.9961 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A17 compound treatment 330560.0 -77700.0 -0.79 297510.0 -96500.0 -1.01 -1.2731 -0.9925 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A18 compound treatment 249380.0 -159000.0 -1.61 263330.0 -131000.0 -1.37 -2.1096 -0.9966 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A19 compound treatment 209300.0 -199000.0 -2.02 169650.0 -224000.0 -2.35 -3.0917 -0.9972 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A20 compound treatment 261690.0 -147000.0 -1.49 298190.0 -95800.0 -1.0 -1.7629 -0.9816 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A21 compound treatment 315600.0 -92600.0 -0.94 365650.0 -28400.0 -0.3 -0.8758 -0.8871 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A22 compound treatment 333990.0 -74300.0 -0.75 342830.0 -51200.0 -0.54 -0.9127 -0.986 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A23 compound treatment 327760.0 -80500.0 -0.82 360350.0 -33700.0 -0.35 -0.8276 -0.9293 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 A24 compound treatment 277210.0 -131000.0 -1.33 295880.0 -98100.0 -1.03 -1.6685 -0.9918 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B01 compound treatment 329450.0 -78800.0 -0.8 324690.0 -69300.0 -0.73 -1.0797 -0.9988 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B02 compound treatment 470580.0 62300.0 0.63 432600.0 38600.0 0.4 0.7339 0.9765 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B03 compound treatment 320190.0 -88100.0 -0.89 310720.0 -83300.0 -0.87 -1.2497 -0.9999 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B04 compound treatment 330020.0 -78200.0 -0.79 279760.0 -114000.0 -1.2 -1.4085 -0.9802 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B05 compound treatment 248020.0 -160000.0 -1.63 299060.0 -94900.0 -0.99 -1.8547 -0.9721 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B06 compound treatment 422210.0 14000.0 0.14 347840.0 -46200.0 -0.48 -0.2416 -0.4794 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B07 compound treatment 327550.0 -80700.0 -0.82 326250.0 -67800.0 -0.71 -1.0818 -0.9974 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B08 compound treatment 157140.0 -251000.0 -2.55 246150.0 -148000.0 -1.55 -2.8997 -0.9714 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B09 compound treatment 312170.0 -96100.0 -0.98 381170.0 -12800.0 -0.13 -0.7854 -0.797 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B10 compound treatment 249000.0 -159000.0 -1.62 303290.0 -90700.0 -0.95 -1.8163 -0.9678 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B11 compound treatment 157880.0 -250000.0 -2.54 146500.0 -248000.0 -2.59 -3.6327 -1.0 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B12 compound treatment 349610.0 -58600.0 -0.6 330530.0 -63500.0 -0.67 -0.8916 -0.9985 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B13 mock treatment 391450.0 -16800.0 -0.17 333450.0 -60600.0 -0.63 -0.5693 -0.8665 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B14 mock treatment 422890.0 14600.0 0.15 444830.0 50800.0 0.53 0.4818 0.8713 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B15 compound treatment 409130.0 886.0 0.01 402340.0 8340.0 0.09 0.0682 0.7759 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B16 compound treatment 343800.0 -64400.0 -0.65 343000.0 -51000.0 -0.53 -0.8409 -0.9949 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B17 compound treatment 183280.0 -225000.0 -2.29 294330.0 -99700.0 -1.04 -2.355 -0.937 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B18 compound treatment 387680.0 -20600.0 -0.21 394340.0 340.0 0.0 -0.1452 -0.695 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B19 compound treatment 242240.0 -166000.0 -1.69 323250.0 -70800.0 -0.74 -1.717 -0.9318 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B20 compound treatment 296210.0 -112000.0 -1.14 276160.0 -118000.0 -1.23 -1.6781 -0.9992 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B21 compound treatment 347810.0 -60400.0 -0.61 360840.0 -33200.0 -0.35 -0.6799 -0.9636 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B22 compound treatment 323530.0 -84700.0 -0.86 374250.0 -19800.0 -0.21 -0.7551 -0.8528 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B23 compound treatment 305650.0 -103000.0 -1.04 344730.0 -49300.0 -0.52 -1.1022 -0.9474 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 B24 compound treatment 267960.0 -140000.0 -1.43 393040.0 -960.0 -0.01 -1.0152 -0.7121 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C01 compound treatment 60270.0 -348000.0 -3.54 82290.0 -312000.0 -3.27 -4.8098 -0.9992 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C02 compound treatment 226300.0 -182000.0 -1.85 224560.0 -169000.0 -1.78 -2.5627 -0.9998 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C03 compound treatment 210190.0 -198000.0 -2.01 323810.0 -70200.0 -0.74 -1.9432 -0.9068 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C04 compound treatment 247750.0 -160000.0 -1.63 326170.0 -67800.0 -0.71 -1.6558 -0.9307 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C05 compound treatment 265140.0 -143000.0 -1.45 317510.0 -76500.0 -0.8 -1.595 -0.9606 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C06 compound treatment 265160.0 -143000.0 -1.45 321800.0 -72200.0 -0.76 -1.5631 -0.9536 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C07 compound treatment 310780.0 -97500.0 -0.99 333360.0 -60600.0 -0.64 -1.1496 -0.977 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C08 compound treatment 338150.0 -70100.0 -0.71 357240.0 -36800.0 -0.39 -0.776 -0.9583 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C09 compound treatment 345780.0 -62500.0 -0.63 370370.0 -23600.0 -0.25 -0.6239 -0.9157 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C10 compound treatment 181520.0 -227000.0 -2.3 225350.0 -169000.0 -1.77 -2.8787 -0.9914 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C11 mock treatment 347450.0 -60800.0 -0.62 420640.0 26600.0 0.28 -0.2395 -0.3533 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C12 mock treatment 368860.0 -39400.0 -0.4 372760.0 -21200.0 -0.22 -0.4404 -0.9616 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C13 compound treatment 209660.0 -199000.0 -2.02 236250.0 -158000.0 -1.65 -2.5957 -0.9951 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C14 compound treatment 232450.0 -176000.0 -1.79 273280.0 -121000.0 -1.26 -2.1576 -0.9857 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C15 mock treatment 409150.0 906.0 0.01 387270.0 -6730.0 -0.07 -0.0434 -0.6096 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C16 mock treatment 337760.0 -70500.0 -0.72 410800.0 16800.0 0.18 -0.382 -0.5179 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C17 compound treatment 225520.0 -183000.0 -1.86 368410.0 -25600.0 -0.27 -1.5026 -0.8009 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C18 compound treatment 207480.0 -201000.0 -2.04 357840.0 -36200.0 -0.38 -1.7105 -0.8243 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C19 compound treatment 233120.0 -175000.0 -1.78 310240.0 -83800.0 -0.88 -1.8789 -0.9469 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C20 compound treatment 257400.0 -151000.0 -1.53 298160.0 -95800.0 -1.0 -1.794 -0.979 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C21 compound treatment 321070.0 -87200.0 -0.89 327060.0 -66900.0 -0.7 -1.1223 -0.9933 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C22 compound treatment 272590.0 -136000.0 -1.38 286630.0 -107000.0 -1.12 -1.7702 -0.9949 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C23 compound treatment 343390.0 -64900.0 -0.66 385780.0 -8220.0 -0.09 -0.5269 -0.7928 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 C24 compound treatment 277000.0 -131000.0 -1.33 314140.0 -79900.0 -0.84 -1.5347 -0.9748 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D01 compound treatment 360720.0 -47500.0 -0.48 330810.0 -63200.0 -0.66 -0.8097 -0.988 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D02 compound treatment 338750.0 -69500.0 -0.71 350580.0 -43400.0 -0.45 -0.8211 -0.9774 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D03 compound treatment 390820.0 -17400.0 -0.18 384320.0 -9680.0 -0.1 -0.1969 -0.965 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D04 compound treatment 267390.0 -141000.0 -1.43 271070.0 -123000.0 -1.29 -1.9229 -0.9986 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D05 compound treatment 196320.0 -212000.0 -2.15 227580.0 -166000.0 -1.74 -2.7558 -0.9945 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D06 compound treatment 196340.0 -212000.0 -2.15 240550.0 -153000.0 -1.61 -2.6595 -0.9896 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D07 compound treatment 370650.0 -37600.0 -0.38 386200.0 -7800.0 -0.08 -0.3279 -0.8394 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D08 compound treatment 144010.0 -264000.0 -2.69 141440.0 -253000.0 -2.65 -3.7699 -1.0 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D09 compound treatment 268070.0 -140000.0 -1.42 262370.0 -132000.0 -1.38 -1.9825 -0.9999 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D10 compound treatment 413410.0 5170.0 0.05 407910.0 13900.0 0.15 0.1402 0.9049 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D11 mock treatment 402650.0 -5590.0 -0.06 331740.0 -62300.0 -0.65 -0.5015 -0.7658 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D12 mock treatment 406120.0 -2120.0 -0.02 333690.0 -60300.0 -0.63 -0.4621 -0.7308 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D13 compound treatment 254190.0 -154000.0 -1.57 375840.0 -18200.0 -0.19 -1.2415 -0.7873 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D14 compound treatment 256090.0 -152000.0 -1.55 330080.0 -63900.0 -0.67 -1.5669 -0.9299 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D15 mock treatment 406260.0 -1980.0 -0.02 375730.0 -18300.0 -0.19 -0.1496 -0.7773 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D16 mock treatment 403600.0 -4640.0 -0.05 409970.0 16000.0 0.17 0.0849 0.4886 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D17 compound treatment 418880.0 10600.0 0.11 458970.0 65000.0 0.68 0.5578 0.8092 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D18 compound treatment 357280.0 -51000.0 -0.52 366740.0 -27300.0 -0.29 -0.5682 -0.9607 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D19 compound treatment 344810.0 -63400.0 -0.64 377310.0 -16700.0 -0.17 -0.5795 -0.8676 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D20 compound treatment 363290.0 -45000.0 -0.46 389520.0 -4480.0 -0.05 -0.3562 -0.7757 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D21 compound treatment 242430.0 -166000.0 -1.69 289290.0 -105000.0 -1.1 -1.9673 -0.9784 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D22 compound treatment 380330.0 -27900.0 -0.28 346160.0 -47800.0 -0.5 -0.555 -0.9637 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D23 compound treatment 249360.0 -159000.0 -1.61 336120.0 -57900.0 -0.61 -1.5705 -0.9106 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 D24 compound treatment 314690.0 -93600.0 -0.95 348000.0 -46000.0 -0.48 -1.0131 -0.9504 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E01 mock treatment 381960.0 -26300.0 -0.27 465440.0 71400.0 0.75 0.3404 0.4283 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E02 mock treatment 326970.0 -81300.0 -0.83 514350.0 120000.0 1.26 0.3076 0.2041 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E03 compound treatment 355650.0 -52600.0 -0.53 337760.0 -56200.0 -0.59 -0.7946 -0.9988 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E04 compound treatment 190180.0 -218000.0 -2.22 217550.0 -176000.0 -1.85 -2.8742 -0.9959 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E05 compound treatment 270250.0 -138000.0 -1.4 416500.0 22500.0 0.24 -0.8249 -0.5801 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E06 compound treatment 310480.0 -97800.0 -0.99 312090.0 -81900.0 -0.86 -1.3094 -0.9973 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E07 compound treatment 175370.0 -233000.0 -2.37 274080.0 -120000.0 -1.26 -2.5618 -0.9561 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E08 compound treatment 229640.0 -179000.0 -1.81 346350.0 -47700.0 -0.5 -1.6364 -0.8693 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E09 mock treatment 365310.0 -42900.0 -0.44 314110.0 -79900.0 -0.84 -0.9004 -0.9539 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E10 mock treatment 461600.0 53400.0 0.54 320560.0 -73400.0 -0.77 -0.1607 -0.1707 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E11 compound treatment 266970.0 -141000.0 -1.44 286120.0 -108000.0 -1.13 -1.8144 -0.993 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E12 compound treatment 279880.0 -128000.0 -1.3 321850.0 -72200.0 -0.76 -1.4569 -0.9663 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E13 compound treatment 338810.0 -69400.0 -0.71 380130.0 -13900.0 -0.15 -0.6017 -0.8352 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E14 compound treatment 302690.0 -106000.0 -1.07 324680.0 -69300.0 -0.73 -1.2721 -0.982 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E15 compound treatment 294920.0 -113000.0 -1.15 336770.0 -57200.0 -0.6 -1.2383 -0.9537 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E16 compound treatment 267460.0 -141000.0 -1.43 347000.0 -47000.0 -0.49 -1.3598 -0.8987 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E17 mock treatment 420070.0 11800.0 0.12 477550.0 83500.0 0.88 0.704 0.7967 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E18 mock treatment 412450.0 4210.0 0.04 377990.0 -16000.0 -0.17 -0.0884 -0.5106 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E19 compound treatment 460260.0 52000.0 0.53 419000.0 25000.0 0.26 0.559 0.9475 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E20 compound treatment 380670.0 -27600.0 -0.28 374760.0 -19200.0 -0.2 -0.3407 -0.9869 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E21 compound treatment 357990.0 -50300.0 -0.51 373730.0 -20300.0 -0.21 -0.5113 -0.9244 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E22 compound treatment 281090.0 -127000.0 -1.29 328960.0 -65000.0 -0.68 -1.3956 -0.9553 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E23 compound treatment 300320.0 -108000.0 -1.1 302500.0 -91500.0 -0.96 -1.4534 -0.9978 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 E24 compound treatment 272320.0 -136000.0 -1.38 272330.0 -122000.0 -1.27 -1.8781 -0.9992 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F01 mock treatment 422260.0 14000.0 0.14 284280.0 -110000.0 -1.15 -0.7122 -0.6148 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F02 mock treatment 471800.0 63600.0 0.65 497280.0 103000.0 1.08 1.2219 0.9696 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F03 compound treatment 290080.0 -118000.0 -1.2 309310.0 -84700.0 -0.89 -1.4765 -0.9889 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F04 compound treatment 276580.0 -132000.0 -1.34 263040.0 -131000.0 -1.37 -1.9163 -0.9999 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F05 compound treatment 266970.0 -141000.0 -1.44 284130.0 -110000.0 -1.15 -1.8291 -0.994 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F06 compound treatment 312160.0 -96100.0 -0.98 326840.0 -67200.0 -0.7 -1.188 -0.9871 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F07 compound treatment 293690.0 -115000.0 -1.16 246670.0 -147000.0 -1.54 -1.9147 -0.9903 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F08 compound treatment 286170.0 -122000.0 -1.24 253500.0 -141000.0 -1.47 -1.9181 -0.9964 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F09 mock treatment 342720.0 -65500.0 -0.67 335860.0 -58100.0 -0.61 -0.9016 -0.999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F10 mock treatment 320530.0 -87700.0 -0.89 341140.0 -52900.0 -0.55 -1.0219 -0.9738 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F11 compound treatment 439880.0 31600.0 0.32 384740.0 -9260.0 -0.1 0.1587 0.4726 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F12 compound treatment 368820.0 -39400.0 -0.4 293150.0 -101000.0 -1.06 -1.0305 -0.9119 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F13 compound treatment 320860.0 -87400.0 -0.89 323150.0 -70900.0 -0.74 -1.1528 -0.996 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F14 compound treatment 361950.0 -46300.0 -0.47 323410.0 -70600.0 -0.74 -0.8556 -0.9761 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F15 compound treatment 216160.0 -192000.0 -1.95 244260.0 -150000.0 -1.57 -2.4896 -0.9941 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F16 compound treatment 269970.0 -138000.0 -1.41 255880.0 -138000.0 -1.45 -2.0169 -0.9999 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F17 mock treatment 393520.0 -14700.0 -0.15 408020.0 14000.0 0.15 -0.0019 -0.0092 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F18 mock treatment 428690.0 20400.0 0.21 326560.0 -67400.0 -0.71 -0.3527 -0.4789 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F19 compound treatment 325200.0 -83000.0 -0.84 323480.0 -70500.0 -0.74 -1.1192 -0.9978 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F20 compound treatment 400260.0 -7980.0 -0.08 474260.0 80300.0 0.84 0.5373 0.6359 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F21 compound treatment 355310.0 -52900.0 -0.54 361600.0 -32400.0 -0.34 -0.6204 -0.9754 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F22 compound treatment 364610.0 -43600.0 -0.44 392330.0 -1670.0 -0.02 -0.3259 -0.7344 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F23 compound treatment 285280.0 -123000.0 -1.25 276050.0 -118000.0 -1.24 -1.7574 -1.0 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 F24 compound treatment 406200.0 -2040.0 -0.02 364990.0 -29000.0 -0.3 -0.2296 -0.7537 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G01 compound treatment 377600.0 -30600.0 -0.31 335620.0 -58400.0 -0.61 -0.6527 -0.951 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G02 compound treatment 351780.0 -56500.0 -0.57 309770.0 -84200.0 -0.88 -1.0298 -0.9783 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G03 mock treatment 497600.0 89400.0 0.91 310660.0 -83300.0 -0.87 0.0246 0.0196 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G04 mock treatment 270370.0 -138000.0 -1.4 451210.0 57200.0 0.6 -0.5669 -0.372 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G05 compound treatment 322460.0 -85800.0 -0.87 412550.0 18500.0 0.19 -0.479 -0.5363 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G06 compound treatment 282080.0 -126000.0 -1.28 325410.0 -68600.0 -0.72 -1.4147 -0.9626 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G07 compound treatment 309050.0 -99200.0 -1.01 318170.0 -75800.0 -0.79 -1.2746 -0.9931 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G08 compound treatment 356920.0 -51300.0 -0.52 347890.0 -46100.0 -0.48 -0.7104 -0.9993 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G09 compound treatment 298400.0 -110000.0 -1.12 312480.0 -81500.0 -0.85 -1.3933 -0.9913 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G10 compound treatment 337450.0 -70800.0 -0.72 295360.0 -98600.0 -1.03 -1.2395 -0.9843 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G11 compound treatment 390400.0 -17800.0 -0.18 340930.0 -53100.0 -0.56 -0.5214 -0.8915 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G12 compound treatment 264100.0 -144000.0 -1.46 162140.0 -232000.0 -2.43 -2.7536 -0.9707 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G13 compound treatment 174900.0 -233000.0 -2.37 196920.0 -197000.0 -2.06 -3.1369 -0.9976 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G14 compound treatment 395930.0 -12300.0 -0.13 376200.0 -17800.0 -0.19 -0.2204 -0.9812 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G15 compound treatment 446010.0 37800.0 0.38 397440.0 3440.0 0.04 0.2969 0.7701 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G16 compound treatment 314090.0 -94200.0 -0.96 295960.0 -98000.0 -1.03 -1.4029 -0.9994 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G17 compound treatment 378170.0 -30100.0 -0.31 339900.0 -54100.0 -0.57 -0.6169 -0.958 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G18 compound treatment 317960.0 -90300.0 -0.92 333950.0 -60100.0 -0.63 -1.0936 -0.9831 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G19 mock treatment 434160.0 25900.0 0.26 415370.0 21400.0 0.22 0.3445 0.9967 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G20 mock treatment 465850.0 57600.0 0.59 456480.0 62500.0 0.65 0.8768 0.9984 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G21 compound treatment 445920.0 37700.0 0.38 428860.0 34900.0 0.37 0.529 0.9997 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G22 compound treatment 249620.0 -159000.0 -1.61 269870.0 -124000.0 -1.3 -2.0595 -0.9943 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G23 compound treatment 333140.0 -75100.0 -0.76 355620.0 -38400.0 -0.4 -0.824 -0.9552 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 G24 compound treatment 287200.0 -121000.0 -1.23 270170.0 -124000.0 -1.3 -1.7872 -0.9996 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H01 compound treatment 121760.0 -286000.0 -2.91 212600.0 -181000.0 -1.9 -3.4025 -0.9786 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H02 compound treatment 339100.0 -69100.0 -0.7 296010.0 -98000.0 -1.03 -1.2228 -0.9829 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H03 mock treatment 459200.0 51000.0 0.52 305490.0 -88500.0 -0.93 -0.2896 -0.2726 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H04 mock treatment 443550.0 35300.0 0.36 351800.0 -42200.0 -0.44 -0.059 -0.1035 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H05 compound treatment 293530.0 -115000.0 -1.17 290420.0 -104000.0 -1.09 -1.5917 -0.9994 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H06 compound treatment 364570.0 -43700.0 -0.44 330110.0 -63900.0 -0.67 -0.7872 -0.9801 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H07 compound treatment 294670.0 -114000.0 -1.15 331600.0 -62400.0 -0.65 -1.2784 -0.9638 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H08 compound treatment 437160.0 28900.0 0.29 319490.0 -74500.0 -0.78 -0.3442 -0.4127 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H09 compound treatment 259360.0 -149000.0 -1.51 226420.0 -168000.0 -1.76 -2.3114 -0.9973 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H10 compound treatment 375450.0 -32800.0 -0.33 272850.0 -121000.0 -1.27 -1.1332 -0.8635 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H11 compound treatment 405180.0 -3060.0 -0.03 323930.0 -70100.0 -0.73 -0.5411 -0.7364 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H12 compound treatment 272550.0 -136000.0 -1.38 356570.0 -37400.0 -0.39 -1.2524 -0.8736 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H13 compound treatment 211630.0 -197000.0 -2.0 277120.0 -117000.0 -1.22 -2.2787 -0.9724 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H14 compound treatment 256510.0 -152000.0 -1.54 304490.0 -89500.0 -0.94 -1.7535 -0.9716 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H15 compound treatment 200960.0 -207000.0 -2.11 221860.0 -172000.0 -1.8 -2.7648 -0.997 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H16 compound treatment 351280.0 -57000.0 -0.58 381760.0 -12200.0 -0.13 -0.5 -0.8433 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H17 compound treatment 430400.0 22200.0 0.23 369280.0 -24700.0 -0.26 -0.0239 -0.0698 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H18 compound treatment 429480.0 21200.0 0.22 436800.0 42800.0 0.45 0.4697 0.9438 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H19 mock treatment 466660.0 58400.0 0.59 430350.0 36300.0 0.38 0.6891 0.977 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H20 mock treatment 431520.0 23300.0 0.24 502580.0 109000.0 1.14 0.9717 0.8362 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H21 compound treatment 248320.0 -160000.0 -1.63 222690.0 -171000.0 -1.79 -2.4184 -0.9988 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H22 compound treatment 268210.0 -140000.0 -1.42 320860.0 -73100.0 -0.77 -1.5481 -0.9578 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H23 compound treatment 312880.0 -95400.0 -0.97 271000.0 -123000.0 -1.29 -1.5965 -0.9901 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 H24 compound treatment 231890.0 -176000.0 -1.79 282360.0 -112000.0 -1.17 -2.0943 -0.9786 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I01 compound treatment 342420.0 -65800.0 -0.67 333090.0 -60900.0 -0.64 -0.9243 -0.9997 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I02 compound treatment 195590.0 -213000.0 -2.16 294790.0 -99200.0 -1.04 -2.2631 -0.9437 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I03 compound treatment 370570.0 -37700.0 -0.38 414890.0 20900.0 0.22 -0.1159 -0.2629 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I04 compound treatment 383590.0 -24700.0 -0.25 384800.0 -9200.0 -0.1 -0.2453 -0.9139 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I05 mock treatment 278200.0 -130000.0 -1.32 294240.0 -99800.0 -1.05 -1.6736 -0.9933 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I06 mock treatment 385970.0 -22300.0 -0.23 385280.0 -8720.0 -0.09 -0.2247 -0.9204 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I07 compound treatment 266270.0 -142000.0 -1.44 301280.0 -92700.0 -0.97 -1.7071 -0.9815 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I08 compound treatment 426880.0 18600.0 0.19 351060.0 -42900.0 -0.45 -0.1842 -0.3774 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I09 compound treatment 429090.0 20800.0 0.21 395420.0 1420.0 0.01 0.1603 0.7549 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I10 compound treatment 299550.0 -109000.0 -1.1 265810.0 -128000.0 -1.34 -1.7308 -0.9953 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I11 compound treatment 354560.0 -53700.0 -0.55 338560.0 -55400.0 -0.58 -0.7965 -0.9995 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I12 compound treatment 294050.0 -114000.0 -1.16 299680.0 -94300.0 -0.99 -1.5194 -0.9968 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I13 compound treatment 375730.0 -32500.0 -0.33 455840.0 61800.0 0.65 0.2245 0.3087 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I14 compound treatment 321920.0 -86300.0 -0.88 335230.0 -58800.0 -0.62 -1.0557 -0.985 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I15 compound treatment 448960.0 40700.0 0.41 402080.0 8080.0 0.08 0.3524 0.8345 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I16 compound treatment 285610.0 -123000.0 -1.25 324220.0 -69800.0 -0.73 -1.3982 -0.9677 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I17 compound treatment 337450.0 -70800.0 -0.72 427630.0 33600.0 0.35 -0.2595 -0.324 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I18 compound treatment 378410.0 -29800.0 -0.3 440480.0 46500.0 0.49 0.13 0.2266 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I19 compound treatment 202080.0 -206000.0 -2.1 299960.0 -94000.0 -0.99 -2.1781 -0.9408 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I20 compound treatment 267400.0 -141000.0 -1.43 305600.0 -88400.0 -0.93 -1.667 -0.9778 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I21 mock treatment 463400.0 55200.0 0.56 423110.0 29100.0 0.3 0.612 0.9591 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I22 mock treatment 428850.0 20600.0 0.21 401950.0 7950.0 0.08 0.207 0.9184 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I23 compound treatment 342360.0 -65900.0 -0.67 309640.0 -84400.0 -0.88 -1.0984 -0.9906 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 I24 compound treatment 325830.0 -82400.0 -0.84 311600.0 -82400.0 -0.86 -1.2027 -0.9999 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J01 compound treatment 100800.0 -307000.0 -3.12 225280.0 -169000.0 -1.77 -3.4592 -0.9636 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J02 compound treatment 226880.0 -181000.0 -1.84 277560.0 -116000.0 -1.22 -2.1659 -0.9799 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J03 compound treatment 272610.0 -136000.0 -1.38 311850.0 -82200.0 -0.86 -1.5833 -0.9743 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J04 compound treatment 377810.0 -30400.0 -0.31 293720.0 -100000.0 -1.05 -0.9616 -0.878 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J05 mock treatment 412480.0 4240.0 0.04 248100.0 -146000.0 -1.53 -1.0505 -0.6869 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J06 mock treatment 428990.0 20700.0 0.21 324330.0 -69700.0 -0.73 -0.3671 -0.4831 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J07 compound treatment 229600.0 -179000.0 -1.82 262810.0 -131000.0 -1.37 -2.2556 -0.9906 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J08 compound treatment 238560.0 -170000.0 -1.72 271530.0 -122000.0 -1.28 -2.1266 -0.9894 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J09 compound treatment 324210.0 -84000.0 -0.85 262080.0 -132000.0 -1.38 -1.5812 -0.9732 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J10 compound treatment 287520.0 -121000.0 -1.23 344770.0 -49200.0 -0.52 -1.2322 -0.9259 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J11 compound treatment 364700.0 -43500.0 -0.44 281150.0 -113000.0 -1.18 -1.149 -0.9101 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J12 compound treatment 396400.0 -11800.0 -0.12 312270.0 -81700.0 -0.86 -0.6906 -0.7986 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J13 compound treatment 323120.0 -85100.0 -0.87 198960.0 -195000.0 -2.04 -2.0567 -0.9268 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J14 compound treatment 85150.0 -323000.0 -3.28 243710.0 -150000.0 -1.57 -3.4351 -0.9434 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J15 compound treatment 362450.0 -45800.0 -0.47 415910.0 21900.0 0.23 -0.1667 -0.3213 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J16 compound treatment 389850.0 -18400.0 -0.19 394110.0 110.0 0.0 -0.1314 -0.7028 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J17 compound treatment 421390.0 13100.0 0.13 424970.0 31000.0 0.32 0.3239 0.9231 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J18 compound treatment 192170.0 -216000.0 -2.2 308850.0 -85200.0 -0.89 -2.1835 -0.9213 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J19 compound treatment 378940.0 -29300.0 -0.3 395950.0 1950.0 0.02 -0.1961 -0.6571 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J20 compound treatment 301690.0 -107000.0 -1.08 380820.0 -13200.0 -0.14 -0.8633 -0.7909 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J21 mock treatment 414010.0 5770.0 0.06 395170.0 1170.0 0.01 0.0501 0.8369 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J22 mock treatment 429650.0 21400.0 0.22 443480.0 49500.0 0.52 0.5204 0.9256 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J23 compound treatment 406770.0 -1470.0 -0.01 365480.0 -28500.0 -0.3 -0.2219 -0.7416 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 J24 compound treatment 212110.0 -196000.0 -1.99 338740.0 -55300.0 -0.58 -1.8188 -0.8763 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K01 compound treatment 345200.0 -63000.0 -0.64 401340.0 7340.0 0.08 -0.3986 -0.6178 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K02 compound treatment 299320.0 -109000.0 -1.11 327280.0 -66700.0 -0.7 -1.277 -0.9754 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K03 compound treatment 353450.0 -54800.0 -0.56 292830.0 -101000.0 -1.06 -1.1433 -0.9548 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K04 compound treatment 248960.0 -159000.0 -1.62 285840.0 -108000.0 -1.13 -1.9459 -0.9848 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K05 compound treatment 234090.0 -174000.0 -1.77 249320.0 -145000.0 -1.52 -2.3233 -0.997 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K06 compound treatment 268250.0 -140000.0 -1.42 273280.0 -121000.0 -1.26 -1.9003 -0.9983 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K07 mock treatment 276010.0 -132000.0 -1.34 380640.0 -13400.0 -0.14 -1.0492 -0.7766 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K08 mock treatment 360080.0 -48200.0 -0.49 465160.0 71200.0 0.75 0.1811 0.2031 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K09 compound treatment 468230.0 60000.0 0.61 458840.0 64800.0 0.68 0.9114 0.9985 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K10 compound treatment 275430.0 -133000.0 -1.35 254490.0 -140000.0 -1.46 -1.988 -0.9992 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K11 compound treatment 255130.0 -153000.0 -1.56 304550.0 -89500.0 -0.94 -1.7629 -0.9706 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K12 compound treatment 325960.0 -82300.0 -0.84 352830.0 -41200.0 -0.43 -0.8963 -0.9526 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K13 compound treatment 442810.0 34600.0 0.35 397670.0 3670.0 0.04 0.2756 0.7798 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K14 compound treatment 326150.0 -82100.0 -0.83 425190.0 31200.0 0.33 -0.3588 -0.4005 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K15 mock treatment 460880.0 52600.0 0.53 378930.0 -15100.0 -0.16 0.2666 0.478 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K16 mock treatment 369240.0 -39000.0 -0.4 395860.0 1860.0 0.02 -0.2665 -0.6715 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K17 compound treatment 485380.0 77100.0 0.78 413120.0 19100.0 0.2 0.6959 0.8602 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K18 compound treatment 411140.0 2900.0 0.03 407760.0 13800.0 0.14 0.1228 0.8343 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K19 compound treatment 348720.0 -59500.0 -0.6 299220.0 -94800.0 -0.99 -1.1299 -0.9717 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K20 compound treatment 318970.0 -89300.0 -0.91 348320.0 -45700.0 -0.48 -0.9799 -0.9554 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K21 compound treatment 453680.0 45400.0 0.46 417640.0 23600.0 0.25 0.5016 0.9574 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K22 compound treatment 229380.0 -179000.0 -1.82 267840.0 -126000.0 -1.32 -2.2199 -0.9878 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K23 mock treatment 403210.0 -5030.0 -0.05 446640.0 52600.0 0.55 0.3538 0.6388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 K24 mock treatment 399250.0 -8990.0 -0.09 391000.0 -3000.0 -0.03 -0.0869 -0.8987 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L01 compound treatment 130770.0 -277000.0 -2.82 270950.0 -123000.0 -1.29 -2.9055 -0.9371 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L02 compound treatment 207550.0 -201000.0 -2.04 335450.0 -58600.0 -0.61 -1.8759 -0.8808 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L03 compound treatment 273240.0 -135000.0 -1.37 316930.0 -77100.0 -0.81 -1.5411 -0.9681 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L04 compound treatment 242530.0 -166000.0 -1.68 290110.0 -104000.0 -1.09 -1.9605 -0.9777 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L05 compound treatment 246690.0 -162000.0 -1.64 295300.0 -98700.0 -1.03 -1.8921 -0.9752 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L06 compound treatment 295520.0 -113000.0 -1.15 283970.0 -110000.0 -1.15 -1.6252 -1.0 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L07 mock treatment 408050.0 -194.0 0.0 395330.0 1330.0 0.01 0.0085 0.6012 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L08 mock treatment 469760.0 61500.0 0.63 440740.0 46700.0 0.49 0.7883 0.9927 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L09 compound treatment 314030.0 -94200.0 -0.96 327280.0 -66700.0 -0.7 -1.1713 -0.9881 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L10 compound treatment 349650.0 -58600.0 -0.6 478200.0 84200.0 0.88 0.2028 0.1905 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L11 compound treatment 252820.0 -155000.0 -1.58 211720.0 -182000.0 -1.91 -2.4673 -0.9955 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L12 compound treatment 320800.0 -87400.0 -0.89 326150.0 -67900.0 -0.71 -1.131 -0.9939 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L13 compound treatment 302880.0 -105000.0 -1.07 241230.0 -153000.0 -1.6 -1.8889 -0.9809 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L14 compound treatment 157760.0 -250000.0 -2.55 100290.0 -294000.0 -3.08 -3.9759 -0.9956 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L15 mock treatment 480220.0 72000.0 0.73 316320.0 -77700.0 -0.81 -0.0583 -0.0533 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L16 mock treatment 459570.0 51300.0 0.52 485060.0 91100.0 0.95 1.0435 0.9596 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L17 compound treatment 319970.0 -88300.0 -0.9 269570.0 -124000.0 -1.3 -1.5562 -0.9834 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L18 compound treatment 214490.0 -194000.0 -1.97 205860.0 -188000.0 -1.97 -2.7861 -1.0 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L19 compound treatment 344240.0 -64000.0 -0.65 314770.0 -79200.0 -0.83 -1.0469 -0.9927 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L20 compound treatment 385040.0 -23200.0 -0.24 379410.0 -14600.0 -0.15 -0.2748 -0.978 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L21 compound treatment 389600.0 -18600.0 -0.19 370080.0 -23900.0 -0.25 -0.3112 -0.9905 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L22 compound treatment 309930.0 -98300.0 -1.0 302090.0 -91900.0 -0.96 -1.3874 -0.9998 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L23 mock treatment 467720.0 59500.0 0.6 368090.0 -25900.0 -0.27 0.2354 0.3553 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 L24 mock treatment 409570.0 1330.0 0.01 368540.0 -25500.0 -0.27 -0.1791 -0.6705 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M01 compound treatment 158050.0 -250000.0 -2.54 208040.0 -186000.0 -1.95 -3.1755 -0.9914 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M02 compound treatment 253010.0 -155000.0 -1.58 276000.0 -118000.0 -1.24 -1.9897 -0.9927 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M03 compound treatment 387680.0 -20600.0 -0.21 411750.0 17700.0 0.19 -0.0163 -0.0581 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M04 compound treatment 273670.0 -135000.0 -1.37 275570.0 -118000.0 -1.24 -1.8444 -0.9988 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M05 compound treatment 396710.0 -11500.0 -0.12 296170.0 -97800.0 -1.03 -0.8077 -0.7829 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M06 compound treatment 238080.0 -170000.0 -1.73 224540.0 -169000.0 -1.78 -2.4782 -0.9999 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M07 compound treatment 352320.0 -55900.0 -0.57 388400.0 -5600.0 -0.06 -0.4433 -0.776 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M08 compound treatment 263630.0 -145000.0 -1.47 224250.0 -170000.0 -1.78 -2.2968 -0.9955 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M09 mock treatment 423960.0 15700.0 0.16 440320.0 46300.0 0.49 0.4561 0.8927 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M10 mock treatment 386400.0 -21800.0 -0.22 436500.0 42500.0 0.45 0.1579 0.3174 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M11 compound treatment 352770.0 -55500.0 -0.56 396320.0 2320.0 0.02 -0.3814 -0.676 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M12 compound treatment 188670.0 -220000.0 -2.23 225830.0 -168000.0 -1.76 -2.8237 -0.9932 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M13 mock treatment 377330.0 -30900.0 -0.31 435710.0 41700.0 0.44 0.0869 0.1614 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M14 mock treatment 451880.0 43600.0 0.44 459040.0 65000.0 0.68 0.7954 0.9783 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M15 compound treatment 328640.0 -79600.0 -0.81 419530.0 25500.0 0.27 -0.3829 -0.4494 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M16 compound treatment 389760.0 -18500.0 -0.19 459530.0 65500.0 0.69 0.3527 0.4955 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M17 compound treatment 360050.0 -48200.0 -0.49 483280.0 89300.0 0.94 0.3151 0.2985 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M18 compound treatment 281980.0 -126000.0 -1.28 341570.0 -52400.0 -0.55 -1.2957 -0.9283 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M19 compound treatment 452870.0 44600.0 0.45 411610.0 17600.0 0.18 0.4511 0.9214 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M20 compound treatment 419610.0 11400.0 0.12 412260.0 18300.0 0.19 0.217 0.9708 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M21 compound treatment 487090.0 78800.0 0.8 428080.0 34100.0 0.36 0.8191 0.9337 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M22 compound treatment 384960.0 -23300.0 -0.24 366950.0 -27100.0 -0.28 -0.3677 -0.996 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M23 compound treatment 43750.0 -364000.0 -3.7 83200.0 -311000.0 -3.26 -4.9218 -0.9979 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 M24 compound treatment 172890.0 -235000.0 -2.39 228810.0 -165000.0 -1.73 -2.915 -0.9874 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N01 compound treatment 185830.0 -222000.0 -2.26 194580.0 -199000.0 -2.09 -3.0756 -0.9992 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N02 compound treatment 250200.0 -158000.0 -1.61 299250.0 -94800.0 -0.99 -1.8376 -0.9733 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N03 compound treatment 138040.0 -270000.0 -2.75 224640.0 -169000.0 -1.77 -3.1963 -0.9777 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N04 compound treatment 342780.0 -65500.0 -0.67 300450.0 -93600.0 -0.98 -1.1635 -0.9822 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N05 compound treatment 262930.0 -145000.0 -1.48 241760.0 -152000.0 -1.6 -2.1721 -0.9993 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N06 compound treatment 365640.0 -42600.0 -0.43 314680.0 -79300.0 -0.83 -0.8938 -0.9538 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N07 compound treatment 192920.0 -215000.0 -2.19 213410.0 -181000.0 -1.89 -2.8852 -0.9974 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N08 compound treatment 78760.0 -329000.0 -3.35 85130.0 -309000.0 -3.24 -4.6559 -0.9999 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N09 mock treatment 374950.0 -33300.0 -0.34 331870.0 -62100.0 -0.65 -0.6995 -0.9535 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N10 mock treatment 434400.0 26200.0 0.27 352230.0 -41800.0 -0.44 -0.1215 -0.2373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N11 compound treatment 164480.0 -244000.0 -2.48 102520.0 -291000.0 -3.05 -3.9111 -0.9946 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N12 compound treatment 291640.0 -117000.0 -1.18 273570.0 -120000.0 -1.26 -1.7301 -0.9995 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N13 mock treatment 387780.0 -20500.0 -0.21 411490.0 17500.0 0.18 -0.0175 -0.063 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N14 mock treatment 418680.0 10400.0 0.11 365040.0 -29000.0 -0.3 -0.1396 -0.4342 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N15 compound treatment 245700.0 -163000.0 -1.65 266080.0 -128000.0 -1.34 -2.1157 -0.9946 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N16 compound treatment 372320.0 -35900.0 -0.37 446460.0 52500.0 0.55 0.1305 0.1978 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N17 compound treatment 194050.0 -214000.0 -2.18 286670.0 -107000.0 -1.12 -2.3343 -0.9528 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N18 compound treatment 270690.0 -138000.0 -1.4 243370.0 -151000.0 -1.58 -2.1044 -0.9982 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N19 compound treatment 349700.0 -58500.0 -0.59 327110.0 -66900.0 -0.7 -0.9163 -0.9967 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N20 compound treatment 325090.0 -83200.0 -0.85 292030.0 -102000.0 -1.07 -1.353 -0.9933 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N21 compound treatment 240810.0 -167000.0 -1.7 257070.0 -137000.0 -1.43 -2.2176 -0.9964 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N22 compound treatment 370990.0 -37300.0 -0.38 344080.0 -49900.0 -0.52 -0.6375 -0.9874 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N23 compound treatment 258840.0 -149000.0 -1.52 253630.0 -140000.0 -1.47 -2.1135 -0.9999 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 N24 compound treatment 205950.0 -202000.0 -2.06 294090.0 -99900.0 -1.05 -2.1938 -0.951 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O01 compound treatment 220450.0 -188000.0 -1.91 241860.0 -152000.0 -1.59 -2.4766 -0.996 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O02 compound treatment 220930.0 -187000.0 -1.9 232360.0 -162000.0 -1.69 -2.5435 -0.9983 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O03 compound treatment 67610.0 -341000.0 -3.46 75780.0 -318000.0 -3.33 -4.8053 -0.9998 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O04 compound treatment 266850.0 -141000.0 -1.44 286790.0 -107000.0 -1.12 -1.8103 -0.9926 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O05 compound treatment 270320.0 -138000.0 -1.4 337380.0 -56600.0 -0.59 -1.4106 -0.9268 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O06 compound treatment 318040.0 -90200.0 -0.92 320260.0 -73700.0 -0.77 -1.1945 -0.9964 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O07 compound treatment 416210.0 7970.0 0.08 449810.0 55800.0 0.58 0.4707 0.7974 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O08 compound treatment 170130.0 -238000.0 -2.42 230680.0 -163000.0 -1.71 -2.921 -0.9856 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O09 compound treatment 41760.0 -366000.0 -3.72 162880.0 -231000.0 -2.42 -4.3457 -0.9783 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O10 compound treatment 217410.0 -191000.0 -1.94 311570.0 -82400.0 -0.86 -1.982 -0.9336 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O11 mock treatment 358910.0 -49300.0 -0.5 413940.0 19900.0 0.21 -0.2068 -0.3807 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O12 mock treatment 442510.0 34300.0 0.35 408270.0 14300.0 0.15 0.3519 0.9287 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O13 compound treatment 310350.0 -97900.0 -0.99 294190.0 -99800.0 -1.05 -1.4429 -0.9997 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O14 compound treatment 325600.0 -82600.0 -0.84 421370.0 27400.0 0.29 -0.3911 -0.4407 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O15 compound treatment 348090.0 -60200.0 -0.61 397760.0 3760.0 0.04 -0.4044 -0.6602 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O16 compound treatment 241930.0 -166000.0 -1.69 246610.0 -147000.0 -1.54 -2.2871 -0.999 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O17 compound treatment 251560.0 -157000.0 -1.59 258740.0 -135000.0 -1.42 -2.128 -0.9983 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O18 compound treatment 319860.0 -88400.0 -0.9 297920.0 -96100.0 -1.01 -1.3469 -0.9984 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O19 compound treatment 213600.0 -195000.0 -1.98 249680.0 -144000.0 -1.51 -2.4679 -0.9912 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O20 compound treatment 293990.0 -114000.0 -1.16 299040.0 -95000.0 -0.99 -1.5245 -0.997 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O21 compound treatment 123520.0 -285000.0 -2.89 124960.0 -269000.0 -2.82 -4.0392 -0.9999 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O22 compound treatment 271060.0 -137000.0 -1.39 332970.0 -61000.0 -0.64 -1.4379 -0.9375 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O23 compound treatment 241080.0 -167000.0 -1.7 244320.0 -150000.0 -1.57 -2.3101 -0.9992 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 O24 compound treatment 185530.0 -223000.0 -2.26 267220.0 -127000.0 -1.33 -2.5396 -0.9678 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P01 compound treatment 201040.0 -207000.0 -2.11 197620.0 -196000.0 -2.06 -2.9438 -0.9999 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P02 compound treatment 23430.0 -385000.0 -3.91 31280.0 -363000.0 -3.8 -5.4524 -0.9999 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P03 compound treatment 93440.0 -315000.0 -3.2 112960.0 -281000.0 -2.94 -4.3442 -0.9991 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P04 compound treatment 24850.0 -383000.0 -3.9 30690.0 -363000.0 -3.81 -5.4466 -0.9999 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P05 compound treatment 71360.0 -337000.0 -3.42 68180.0 -326000.0 -3.41 -4.8347 -1.0 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P06 compound treatment 88200.0 -320000.0 -3.25 118680.0 -275000.0 -2.88 -4.3395 -0.9982 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P07 compound treatment 204800.0 -203000.0 -2.07 251290.0 -143000.0 -1.5 -2.5192 -0.9873 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P08 compound treatment 184320.0 -224000.0 -2.28 233630.0 -160000.0 -1.68 -2.7972 -0.9889 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P09 compound treatment 164900.0 -243000.0 -2.47 176160.0 -218000.0 -2.28 -3.3625 -0.9992 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P10 compound treatment 244920.0 -163000.0 -1.66 252880.0 -141000.0 -1.48 -2.2191 -0.9983 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P11 mock treatment 380060.0 -28200.0 -0.29 364260.0 -29700.0 -0.31 -0.4229 -0.9991 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P12 mock treatment 336690.0 -71600.0 -0.73 397410.0 3410.0 0.04 -0.4889 -0.6716 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P13 compound treatment 117280.0 -291000.0 -2.96 151560.0 -242000.0 -2.54 -3.887 -0.9971 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P14 compound treatment 256670.0 -152000.0 -1.54 278270.0 -116000.0 -1.21 -1.9466 -0.993 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P15 compound treatment 205650.0 -203000.0 -2.06 224510.0 -169000.0 -1.78 -2.7115 -0.9973 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P16 compound treatment 302790.0 -105000.0 -1.07 348160.0 -45800.0 -0.48 -1.0974 -0.9345 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P17 compound treatment 209250.0 -199000.0 -2.02 211270.0 -183000.0 -1.91 -2.7837 -0.9996 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P18 compound treatment 227110.0 -181000.0 -1.84 220860.0 -173000.0 -1.81 -2.5843 -1.0 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P19 compound treatment 154950.0 -253000.0 -2.57 186440.0 -208000.0 -2.17 -3.3578 -0.9965 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P20 compound treatment 72210.0 -336000.0 -3.41 187870.0 -206000.0 -2.16 -3.9418 -0.9756 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P21 compound treatment 84550.0 -324000.0 -3.29 175520.0 -218000.0 -2.29 -3.9446 -0.9843 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P22 compound treatment 283730.0 -125000.0 -1.27 381780.0 -12200.0 -0.13 -0.9853 -0.7747 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P23 compound treatment 244640.0 -164000.0 -1.66 328240.0 -65800.0 -0.69 -1.6628 -0.9239 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2093 P24 compound treatment 23870.0 -384000.0 -3.91 98960.0 -295000.0 -3.09 -4.9479 -0.9933 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A01 compound treatment 341880.0 -62500.0 -0.64 341980.0 -53800.0 -0.56 -0.8479 -0.9982 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A02 compound treatment 192750.0 -212000.0 -2.15 190150.0 -206000.0 -2.15 -3.0444 -1.0 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A03 compound treatment 319890.0 -84500.0 -0.86 435400.0 39600.0 0.42 -0.3138 -0.329 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A04 compound treatment 319080.0 -85300.0 -0.87 243960.0 -152000.0 -1.59 -1.738 -0.9593 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A05 compound treatment 342400.0 -62000.0 -0.63 310740.0 -85000.0 -0.89 -1.0756 -0.9856 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A06 compound treatment 304160.0 -100000.0 -1.02 303520.0 -92300.0 -0.97 -1.4039 -0.9997 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A07 compound treatment 306050.0 -98400.0 -1.0 300720.0 -95100.0 -1.0 -1.4111 -1.0 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A08 compound treatment 299290.0 -105000.0 -1.07 266790.0 -129000.0 -1.35 -1.711 -0.9932 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A09 compound treatment 286840.0 -118000.0 -1.19 365460.0 -30300.0 -0.32 -1.0695 -0.8651 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A10 compound treatment 323250.0 -81200.0 -0.82 290170.0 -106000.0 -1.11 -1.3656 -0.9895 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A11 compound treatment 224540.0 -180000.0 -1.83 250460.0 -145000.0 -1.52 -2.3691 -0.9959 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A12 compound treatment 233290.0 -171000.0 -1.74 240130.0 -156000.0 -1.63 -2.3828 -0.9995 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A13 mock treatment 430240.0 25800.0 0.26 341960.0 -53800.0 -0.56 -0.2131 -0.3427 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A14 mock treatment 415040.0 10600.0 0.11 432880.0 37100.0 0.39 0.3512 0.8706 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A15 compound treatment 269220.0 -135000.0 -1.37 299450.0 -96300.0 -1.01 -1.6851 -0.9885 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A16 compound treatment 255150.0 -149000.0 -1.52 249130.0 -147000.0 -1.54 -2.159 -1.0 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A17 compound treatment 389550.0 -14900.0 -0.15 371740.0 -24000.0 -0.25 -0.2849 -0.9701 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A18 compound treatment 266150.0 -138000.0 -1.41 318850.0 -76900.0 -0.81 -1.5635 -0.9652 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A19 compound treatment 276000.0 -128000.0 -1.3 266680.0 -129000.0 -1.35 -1.8792 -0.9998 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A20 compound treatment 371900.0 -32500.0 -0.33 336160.0 -59600.0 -0.62 -0.6753 -0.9557 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A21 compound treatment 425170.0 20800.0 0.21 371410.0 -24400.0 -0.26 -0.0314 -0.0948 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A22 compound treatment 365290.0 -39100.0 -0.4 404730.0 8950.0 0.09 -0.2148 -0.5259 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A23 compound treatment 377370.0 -27000.0 -0.27 367520.0 -28300.0 -0.3 -0.4037 -0.9993 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 A24 compound treatment 366440.0 -38000.0 -0.39 380860.0 -14900.0 -0.16 -0.3834 -0.9209 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B01 compound treatment 305230.0 -99200.0 -1.01 305280.0 -90500.0 -0.95 -1.3832 -0.9995 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B02 compound treatment 325970.0 -78400.0 -0.8 368090.0 -27700.0 -0.29 -0.7688 -0.9063 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B03 compound treatment 386100.0 -18300.0 -0.19 311380.0 -84400.0 -0.88 -0.7569 -0.8376 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B04 compound treatment 320700.0 -83700.0 -0.85 373450.0 -22300.0 -0.23 -0.767 -0.8693 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B05 compound treatment 380870.0 -23500.0 -0.24 349540.0 -46200.0 -0.48 -0.5117 -0.9471 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B06 compound treatment 325490.0 -78900.0 -0.8 292380.0 -103000.0 -1.08 -1.3332 -0.989 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B07 compound treatment 349210.0 -55200.0 -0.56 330730.0 -65100.0 -0.68 -0.8786 -0.9953 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B08 compound treatment 363170.0 -41200.0 -0.42 331790.0 -64000.0 -0.67 -0.7704 -0.9744 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B09 compound treatment 380560.0 -23900.0 -0.24 329180.0 -66600.0 -0.7 -0.6648 -0.9 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B10 compound treatment 300160.0 -104000.0 -1.06 284480.0 -111000.0 -1.17 -1.5737 -0.9989 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B11 compound treatment 221370.0 -183000.0 -1.86 245040.0 -151000.0 -1.58 -2.4321 -0.9967 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B12 compound treatment 223010.0 -181000.0 -1.84 151040.0 -245000.0 -2.56 -3.1167 -0.9869 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B13 mock treatment 356890.0 -47500.0 -0.48 472560.0 76800.0 0.8 0.2274 0.2423 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B14 mock treatment 414170.0 9760.0 0.1 437630.0 41800.0 0.44 0.3802 0.8457 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B15 compound treatment 334040.0 -70400.0 -0.72 359060.0 -36700.0 -0.38 -0.7777 -0.9577 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B16 compound treatment 218880.0 -186000.0 -1.89 216850.0 -179000.0 -1.87 -2.6588 -1.0 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B17 compound treatment 396270.0 -8140.0 -0.08 317490.0 -78300.0 -0.82 -0.6385 -0.7745 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B18 compound treatment 353450.0 -51000.0 -0.52 306470.0 -89300.0 -0.94 -1.0279 -0.9611 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B19 compound treatment 361510.0 -42900.0 -0.44 350140.0 -45600.0 -0.48 -0.6464 -0.9989 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B20 compound treatment 197920.0 -206000.0 -2.1 214250.0 -182000.0 -1.9 -2.8287 -0.9988 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B21 compound treatment 365400.0 -39000.0 -0.4 382420.0 -13400.0 -0.14 -0.3793 -0.9022 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B22 compound treatment 318210.0 -86200.0 -0.88 316060.0 -79700.0 -0.84 -1.21 -0.9997 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B23 compound treatment 410310.0 5900.0 0.06 350850.0 -44900.0 -0.47 -0.2905 -0.6121 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 B24 compound treatment 349770.0 -54600.0 -0.56 366470.0 -29300.0 -0.31 -0.6098 -0.961 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C01 compound treatment 347720.0 -56700.0 -0.58 381140.0 -14600.0 -0.15 -0.5158 -0.8652 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C02 compound treatment 328760.0 -75700.0 -0.77 249540.0 -146000.0 -1.53 -1.6271 -0.9491 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C03 compound treatment 264220.0 -140000.0 -1.42 327300.0 -68500.0 -0.72 -1.5147 -0.9496 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C04 compound treatment 330140.0 -74300.0 -0.75 310110.0 -85700.0 -0.9 -1.1684 -0.9963 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C05 compound treatment 261980.0 -142000.0 -1.45 266080.0 -130000.0 -1.36 -1.9844 -0.9995 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C06 compound treatment 300120.0 -104000.0 -1.06 306340.0 -89400.0 -0.94 -1.412 -0.9981 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C07 compound treatment 341280.0 -63100.0 -0.64 281210.0 -115000.0 -1.2 -1.3025 -0.9569 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C08 compound treatment 372320.0 -32100.0 -0.33 305620.0 -90200.0 -0.94 -0.8986 -0.8991 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C09 compound treatment 372850.0 -31600.0 -0.32 316650.0 -79100.0 -0.83 -0.813 -0.9146 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C10 compound treatment 278560.0 -126000.0 -1.28 168240.0 -228000.0 -2.38 -2.5901 -0.9574 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C11 mock treatment 318920.0 -85500.0 -0.87 320320.0 -75500.0 -0.79 -1.1734 -0.9989 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C12 mock treatment 404120.0 -291.0 0.0 367360.0 -28400.0 -0.3 -0.2127 -0.7141 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C13 compound treatment 363280.0 -41100.0 -0.42 333280.0 -62500.0 -0.65 -0.7586 -0.9765 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C14 compound treatment 284370.0 -120000.0 -1.22 258930.0 -137000.0 -1.43 -1.8765 -0.9968 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C15 mock treatment 436200.0 31800.0 0.32 308270.0 -87500.0 -0.92 -0.4199 -0.432 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C16 mock treatment 363260.0 -41200.0 -0.42 317470.0 -78300.0 -0.82 -0.8759 -0.9511 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C17 compound treatment 286460.0 -118000.0 -1.2 358310.0 -37500.0 -0.39 -1.1252 -0.8921 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C18 compound treatment 309020.0 -95400.0 -0.97 281480.0 -114000.0 -1.2 -1.5323 -0.9945 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C19 compound treatment 410270.0 5860.0 0.06 336800.0 -59000.0 -0.62 -0.3949 -0.636 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C20 compound treatment 271410.0 -133000.0 -1.35 254280.0 -142000.0 -1.48 -2.004 -0.9989 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C21 compound treatment 326770.0 -77600.0 -0.79 323360.0 -72400.0 -0.76 -1.0945 -0.9998 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C22 compound treatment 345240.0 -59200.0 -0.6 344910.0 -50900.0 -0.53 -0.8021 -0.9982 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C23 compound treatment 364020.0 -40400.0 -0.41 374770.0 -21000.0 -0.22 -0.4459 -0.9574 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 C24 compound treatment 323800.0 -80600.0 -0.82 314480.0 -81300.0 -0.85 -1.1816 -0.9998 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D01 compound treatment 308880.0 -95500.0 -0.97 259000.0 -137000.0 -1.43 -1.6998 -0.982 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D02 compound treatment 325040.0 -79400.0 -0.81 353490.0 -42300.0 -0.44 -0.8837 -0.9602 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D03 compound treatment 255100.0 -149000.0 -1.52 224660.0 -171000.0 -1.79 -2.3407 -0.9966 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D04 compound treatment 275630.0 -129000.0 -1.31 268920.0 -127000.0 -1.33 -1.8653 -1.0 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D05 compound treatment 279570.0 -125000.0 -1.27 234300.0 -161000.0 -1.69 -2.0934 -0.9899 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D06 compound treatment 411360.0 6950.0 0.07 240380.0 -155000.0 -1.63 -1.1014 -0.6758 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D07 compound treatment 339740.0 -64700.0 -0.66 345350.0 -50400.0 -0.53 -0.8383 -0.9942 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D08 compound treatment 390970.0 -13400.0 -0.14 365720.0 -30100.0 -0.31 -0.3193 -0.9301 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D09 compound treatment 393640.0 -10800.0 -0.11 447520.0 51700.0 0.54 0.3059 0.5532 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D10 compound treatment 346330.0 -58100.0 -0.59 235640.0 -160000.0 -1.68 -1.6038 -0.9017 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D11 mock treatment 392980.0 -11400.0 -0.12 379200.0 -16600.0 -0.17 -0.205 -0.9808 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D12 mock treatment 454350.0 49900.0 0.51 409970.0 14200.0 0.15 0.464 0.8774 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D13 compound treatment 332110.0 -72300.0 -0.73 274490.0 -121000.0 -1.27 -1.4181 -0.9661 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D14 compound treatment 311400.0 -93000.0 -0.95 287520.0 -108000.0 -1.13 -1.4704 -0.9959 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D15 mock treatment 410080.0 5670.0 0.06 364810.0 -31000.0 -0.32 -0.1887 -0.5726 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D16 mock treatment 399590.0 -4820.0 -0.05 406400.0 10600.0 0.11 0.044 0.3622 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D17 compound treatment 305790.0 -98600.0 -1.0 349040.0 -46700.0 -0.49 -1.055 -0.9458 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D18 compound treatment 334020.0 -70400.0 -0.72 303210.0 -92600.0 -0.97 -1.1916 -0.9888 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D19 compound treatment 382440.0 -22000.0 -0.22 327200.0 -68600.0 -0.72 -0.666 -0.8851 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D20 compound treatment 310340.0 -94100.0 -0.96 296090.0 -99700.0 -1.04 -1.4145 -0.999 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D21 compound treatment 308000.0 -96400.0 -0.98 298000.0 -97800.0 -1.02 -1.4172 -0.9998 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D22 compound treatment 345520.0 -58900.0 -0.6 299390.0 -96400.0 -1.01 -1.1373 -0.9688 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D23 compound treatment 397470.0 -6940.0 -0.07 357950.0 -37800.0 -0.4 -0.3302 -0.8201 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 D24 compound treatment 342530.0 -61900.0 -0.63 298850.0 -96900.0 -1.02 -1.1628 -0.9734 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E01 mock treatment 400830.0 -3580.0 -0.04 475320.0 79500.0 0.83 0.5636 0.6756 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E02 mock treatment 430790.0 26400.0 0.27 402240.0 6460.0 0.07 0.2374 0.8587 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E03 compound treatment 363270.0 -41100.0 -0.42 410240.0 14500.0 0.15 -0.1885 -0.4239 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E04 compound treatment 335200.0 -69200.0 -0.7 275630.0 -120000.0 -1.26 -1.3875 -0.9622 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E05 compound treatment 352160.0 -52300.0 -0.53 366290.0 -29500.0 -0.31 -0.5939 -0.9668 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E06 compound treatment 311970.0 -92400.0 -0.94 346320.0 -49500.0 -0.52 -1.0307 -0.9607 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E07 compound treatment 221160.0 -183000.0 -1.86 221210.0 -175000.0 -1.83 -2.6101 -1.0 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E08 compound treatment 347110.0 -57300.0 -0.58 370190.0 -25600.0 -0.27 -0.6013 -0.938 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E09 mock treatment 349120.0 -55300.0 -0.56 362670.0 -33100.0 -0.35 -0.6426 -0.9732 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E10 mock treatment 424050.0 19600.0 0.2 328130.0 -67700.0 -0.71 -0.3601 -0.489 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E11 compound treatment 345120.0 -59300.0 -0.6 270210.0 -126000.0 -1.32 -1.3564 -0.9373 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E12 compound treatment 395290.0 -9120.0 -0.09 414510.0 18700.0 0.2 0.0732 0.3374 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E13 compound treatment 376110.0 -28300.0 -0.29 372370.0 -23400.0 -0.25 -0.3768 -0.9969 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E14 compound treatment 382500.0 -21900.0 -0.22 332090.0 -63700.0 -0.67 -0.6293 -0.8946 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E15 compound treatment 375520.0 -28900.0 -0.29 307310.0 -88500.0 -0.93 -0.8631 -0.8876 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E16 compound treatment 356870.0 -47500.0 -0.48 379410.0 -16400.0 -0.17 -0.4629 -0.9029 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E17 mock treatment 432480.0 28100.0 0.29 396970.0 1190.0 0.01 0.2105 0.7373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E18 mock treatment 394820.0 -9590.0 -0.1 383440.0 -12300.0 -0.13 -0.1603 -0.9903 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E19 compound treatment 423200.0 18800.0 0.19 396960.0 1180.0 0.01 0.1437 0.7513 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E20 compound treatment 388260.0 -16200.0 -0.16 286330.0 -109000.0 -1.15 -0.9269 -0.8002 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E21 compound treatment 293040.0 -111000.0 -1.13 283010.0 -113000.0 -1.18 -1.6358 -0.9998 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E22 compound treatment 337150.0 -67300.0 -0.68 322330.0 -73500.0 -0.77 -1.0275 -0.9983 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E23 compound treatment 364590.0 -39800.0 -0.4 356040.0 -39700.0 -0.42 -0.5806 -0.9999 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 E24 compound treatment 314960.0 -89500.0 -0.91 360180.0 -35600.0 -0.37 -0.9065 -0.9226 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F01 mock treatment 486030.0 81600.0 0.83 454500.0 58700.0 0.62 1.0215 0.9892 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F02 mock treatment 385410.0 -19000.0 -0.19 440890.0 45100.0 0.47 0.1977 0.3872 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F03 compound treatment 286520.0 -118000.0 -1.2 290880.0 -105000.0 -1.1 -1.6243 -0.9991 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F04 compound treatment 253540.0 -151000.0 -1.53 271230.0 -125000.0 -1.3 -2.0069 -0.9968 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F05 compound treatment 380390.0 -24000.0 -0.24 293060.0 -103000.0 -1.08 -0.9336 -0.846 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F06 compound treatment 276770.0 -128000.0 -1.3 254560.0 -141000.0 -1.48 -1.9635 -0.9978 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F07 compound treatment 218020.0 -186000.0 -1.89 213970.0 -182000.0 -1.9 -2.6863 -1.0 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F08 compound treatment 281880.0 -123000.0 -1.25 170210.0 -226000.0 -2.36 -2.5517 -0.9552 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F09 mock treatment 345060.0 -59400.0 -0.6 396640.0 859.0 0.01 -0.4201 -0.6965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F10 mock treatment 457090.0 52700.0 0.54 347960.0 -47800.0 -0.5 0.0242 0.0331 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F11 compound treatment 294130.0 -110000.0 -1.12 304380.0 -91400.0 -0.96 -1.4696 -0.9969 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F12 compound treatment 318400.0 -86000.0 -0.87 332680.0 -63100.0 -0.66 -1.0855 -0.9905 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F13 compound treatment 393920.0 -10500.0 -0.11 344410.0 -51400.0 -0.54 -0.456 -0.831 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F14 compound treatment 318480.0 -85900.0 -0.87 222530.0 -173000.0 -1.82 -1.901 -0.9437 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F15 compound treatment 357840.0 -46600.0 -0.47 219090.0 -177000.0 -1.85 -1.6437 -0.8602 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F16 compound treatment 255370.0 -149000.0 -1.51 228010.0 -168000.0 -1.76 -2.3139 -0.9972 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F17 mock treatment 429300.0 24900.0 0.25 408000.0 12200.0 0.13 0.2694 0.9502 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F18 mock treatment 381370.0 -23000.0 -0.23 341320.0 -54500.0 -0.57 -0.5691 -0.9226 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F19 compound treatment 364640.0 -39800.0 -0.4 289000.0 -107000.0 -1.12 -1.0769 -0.9053 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F20 compound treatment 258720.0 -146000.0 -1.48 181980.0 -214000.0 -2.24 -2.6309 -0.9798 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F21 compound treatment 400350.0 -4060.0 -0.04 393010.0 -2770.0 -0.03 -0.0497 -0.9852 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F22 compound treatment 324410.0 -80000.0 -0.81 225760.0 -170000.0 -1.78 -1.8345 -0.9369 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F23 compound treatment 396640.0 -7770.0 -0.08 379550.0 -16200.0 -0.17 -0.1761 -0.9391 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 F24 compound treatment 344800.0 -59600.0 -0.61 336490.0 -59300.0 -0.62 -0.8676 -0.9999 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G01 compound treatment 344480.0 -59900.0 -0.61 411700.0 15900.0 0.17 -0.3127 -0.4952 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G02 compound treatment 495260.0 90800.0 0.92 395240.0 -541.0 -0.01 0.6488 0.7028 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G03 mock treatment 380570.0 -23800.0 -0.24 443720.0 47900.0 0.5 0.1839 0.3297 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G04 mock treatment 307040.0 -97400.0 -0.99 432960.0 37200.0 0.39 -0.4242 -0.3989 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G05 compound treatment 382720.0 -21700.0 -0.22 329570.0 -66200.0 -0.69 -0.6464 -0.888 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G06 compound treatment 327750.0 -76700.0 -0.78 333990.0 -61800.0 -0.65 -1.0087 -0.9958 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G07 compound treatment 422530.0 18100.0 0.18 235920.0 -160000.0 -1.67 -1.0542 -0.6256 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G08 compound treatment 348600.0 -55800.0 -0.57 339210.0 -56600.0 -0.59 -0.8202 -0.9998 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G09 compound treatment 333070.0 -71300.0 -0.72 260660.0 -135000.0 -1.42 -1.5137 -0.9517 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G10 compound treatment 371450.0 -33000.0 -0.33 248480.0 -147000.0 -1.54 -1.3282 -0.841 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G11 compound treatment 382560.0 -21900.0 -0.22 380120.0 -15700.0 -0.16 -0.273 -0.9889 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G12 compound treatment 294940.0 -109000.0 -1.11 301620.0 -94200.0 -0.99 -1.4842 -0.9982 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G13 compound treatment 468650.0 64200.0 0.65 344490.0 -51300.0 -0.54 0.0816 0.0965 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G14 compound treatment 417370.0 13000.0 0.13 376170.0 -19600.0 -0.21 -0.0522 -0.2138 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G15 compound treatment 475520.0 71100.0 0.72 412880.0 17100.0 0.18 0.6376 0.8565 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G16 compound treatment 279930.0 -124000.0 -1.26 317120.0 -78700.0 -0.82 -1.4773 -0.9785 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G17 compound treatment 361070.0 -43300.0 -0.44 383700.0 -12100.0 -0.13 -0.4009 -0.8749 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G18 compound treatment 366190.0 -38200.0 -0.39 341850.0 -53900.0 -0.57 -0.6742 -0.9833 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G19 mock treatment 392430.0 -12000.0 -0.12 386190.0 -9590.0 -0.1 -0.1571 -0.9955 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G20 mock treatment 384120.0 -20300.0 -0.21 406080.0 10300.0 0.11 -0.0695 -0.2986 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G21 compound treatment 410880.0 6470.0 0.07 359890.0 -35900.0 -0.38 -0.2194 -0.5748 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G22 compound treatment 430960.0 26500.0 0.27 360730.0 -35100.0 -0.37 -0.0689 -0.1512 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G23 compound treatment 385980.0 -18400.0 -0.19 385280.0 -10500.0 -0.11 -0.2102 -0.9678 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 G24 compound treatment 413820.0 9410.0 0.1 406280.0 10500.0 0.11 0.1454 0.9976 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H01 compound treatment 241400.0 -163000.0 -1.66 338790.0 -57000.0 -0.6 -1.5936 -0.905 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H02 compound treatment 303420.0 -101000.0 -1.03 314450.0 -81300.0 -0.85 -1.3282 -0.9957 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H03 mock treatment 348870.0 -55500.0 -0.56 376090.0 -19700.0 -0.21 -0.545 -0.9069 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H04 mock treatment 414080.0 9670.0 0.1 437600.0 41800.0 0.44 0.3793 0.8447 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H05 compound treatment 321440.0 -83000.0 -0.84 326340.0 -69400.0 -0.73 -1.1107 -0.9973 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H06 compound treatment 268420.0 -136000.0 -1.38 230900.0 -165000.0 -1.73 -2.1987 -0.9939 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H07 compound treatment 321760.0 -82700.0 -0.84 303060.0 -92700.0 -0.97 -1.2808 -0.9974 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H08 compound treatment 294900.0 -110000.0 -1.11 227410.0 -168000.0 -1.76 -2.0343 -0.9753 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H09 compound treatment 322260.0 -82200.0 -0.83 297500.0 -98300.0 -1.03 -1.3184 -0.9946 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H10 compound treatment 332120.0 -72300.0 -0.73 308480.0 -87300.0 -0.91 -1.1662 -0.9941 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H11 compound treatment 272190.0 -132000.0 -1.34 297440.0 -98300.0 -1.03 -1.6787 -0.9914 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H12 compound treatment 293490.0 -111000.0 -1.13 229710.0 -166000.0 -1.74 -2.0274 -0.9779 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H13 compound treatment 295090.0 -109000.0 -1.11 351380.0 -44400.0 -0.47 -1.1145 -0.9254 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H14 compound treatment 347480.0 -56900.0 -0.58 329930.0 -65900.0 -0.69 -0.897 -0.9962 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H15 compound treatment 352350.0 -52100.0 -0.53 357440.0 -38300.0 -0.4 -0.6582 -0.9908 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H16 compound treatment 315610.0 -88800.0 -0.9 359770.0 -36000.0 -0.38 -0.9049 -0.9251 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H17 compound treatment 411840.0 7430.0 0.08 438720.0 42900.0 0.45 0.3715 0.8144 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H18 compound treatment 333650.0 -70800.0 -0.72 304750.0 -91000.0 -0.95 -1.1829 -0.9903 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H19 mock treatment 407490.0 3080.0 0.03 413790.0 18000.0 0.19 0.1555 0.8133 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H20 mock treatment 420900.0 16500.0 0.17 426190.0 30400.0 0.32 0.3438 0.955 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H21 compound treatment 344660.0 -59800.0 -0.61 356270.0 -39500.0 -0.41 -0.7221 -0.9826 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H22 compound treatment 357760.0 -46700.0 -0.47 341970.0 -53800.0 -0.56 -0.7339 -0.9963 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H23 compound treatment 395840.0 -8570.0 -0.09 324600.0 -71200.0 -0.75 -0.5889 -0.7844 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 H24 compound treatment 373390.0 -31000.0 -0.32 343880.0 -51900.0 -0.54 -0.6074 -0.9664 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I01 compound treatment 325220.0 -79200.0 -0.8 414750.0 19000.0 0.2 -0.4285 -0.5169 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I02 compound treatment 383250.0 -21200.0 -0.22 265450.0 -130000.0 -1.37 -1.1176 -0.8085 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I03 compound treatment 392420.0 -12000.0 -0.12 260120.0 -136000.0 -1.42 -1.0912 -0.7649 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I04 compound treatment 290100.0 -114000.0 -1.16 291930.0 -104000.0 -1.09 -1.5908 -0.9995 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I05 mock treatment 387520.0 -16900.0 -0.17 429160.0 33400.0 0.35 0.1259 0.3232 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I06 mock treatment 329760.0 -74700.0 -0.76 364500.0 -31300.0 -0.33 -0.7682 -0.9296 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I07 compound treatment 336640.0 -67800.0 -0.69 283840.0 -112000.0 -1.17 -1.3163 -0.9678 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I08 compound treatment 328600.0 -75800.0 -0.77 368990.0 -26800.0 -0.28 -0.7432 -0.9065 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I09 compound treatment 395010.0 -9400.0 -0.1 371360.0 -24400.0 -0.26 -0.2485 -0.9098 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I10 compound treatment 395460.0 -8950.0 -0.09 308000.0 -87800.0 -0.92 -0.7147 -0.7733 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I11 compound treatment 274270.0 -130000.0 -1.32 280750.0 -115000.0 -1.21 -1.7874 -0.9989 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I12 compound treatment 243170.0 -161000.0 -1.64 318450.0 -77300.0 -0.81 -1.7316 -0.9473 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I13 compound treatment 404830.0 419.0 0.0 370720.0 -25100.0 -0.26 -0.1827 -0.6955 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I14 compound treatment 388000.0 -16400.0 -0.17 364050.0 -31700.0 -0.33 -0.353 -0.9491 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I15 compound treatment 384580.0 -19800.0 -0.2 339160.0 -56600.0 -0.59 -0.562 -0.897 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I16 compound treatment 305700.0 -98700.0 -1.0 350000.0 -45800.0 -0.48 -1.0485 -0.943 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I17 compound treatment 412260.0 7850.0 0.08 354720.0 -41100.0 -0.43 -0.2478 -0.5664 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I18 compound treatment 336450.0 -68000.0 -0.69 265370.0 -130000.0 -1.37 -1.4545 -0.95 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I19 compound treatment 416770.0 12400.0 0.13 368370.0 -27400.0 -0.29 -0.1143 -0.3645 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I20 compound treatment 397620.0 -6790.0 -0.07 361620.0 -34200.0 -0.36 -0.3019 -0.8282 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I21 mock treatment 421600.0 17200.0 0.17 408680.0 12900.0 0.14 0.2191 0.992 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I22 mock treatment 378310.0 -26100.0 -0.27 417040.0 21300.0 0.22 -0.0301 -0.0868 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I23 compound treatment 400770.0 -3640.0 -0.04 395070.0 -711.0 -0.01 -0.0314 -0.8328 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 I24 compound treatment 358240.0 -46200.0 -0.47 341400.0 -54400.0 -0.57 -0.7347 -0.9953 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J01 compound treatment 286880.0 -118000.0 -1.19 318260.0 -77500.0 -0.81 -1.4189 -0.9823 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J02 compound treatment 283590.0 -121000.0 -1.23 299070.0 -96700.0 -1.01 -1.5847 -0.9955 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J03 compound treatment 278610.0 -126000.0 -1.28 300320.0 -95500.0 -1.0 -1.6112 -0.9926 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J04 compound treatment 327570.0 -76800.0 -0.78 282980.0 -113000.0 -1.18 -1.3879 -0.9798 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J05 mock treatment 398790.0 -5620.0 -0.06 282980.0 -113000.0 -1.18 -0.8761 -0.7404 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J06 mock treatment 432450.0 28000.0 0.28 330140.0 -65600.0 -0.69 -0.2848 -0.3826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J07 compound treatment 333980.0 -70400.0 -0.72 272640.0 -123000.0 -1.29 -1.4184 -0.9614 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J08 compound treatment 349920.0 -54500.0 -0.55 240880.0 -155000.0 -1.62 -1.5392 -0.8976 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J09 compound treatment 317200.0 -87200.0 -0.89 329640.0 -66100.0 -0.69 -1.1167 -0.9926 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J10 compound treatment 359570.0 -44800.0 -0.46 278990.0 -117000.0 -1.22 -1.1875 -0.9094 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J11 compound treatment 291970.0 -112000.0 -1.14 323720.0 -72100.0 -0.76 -1.3418 -0.9798 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J12 compound treatment 266340.0 -138000.0 -1.4 278340.0 -117000.0 -1.23 -1.8622 -0.9979 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J13 compound treatment 310080.0 -94300.0 -0.96 318530.0 -77300.0 -0.81 -1.2502 -0.9965 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J14 compound treatment 382330.0 -22100.0 -0.22 354560.0 -41200.0 -0.43 -0.4641 -0.9535 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J15 compound treatment 388480.0 -15900.0 -0.16 350890.0 -44900.0 -0.47 -0.4471 -0.8987 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J16 compound treatment 371360.0 -33100.0 -0.34 328320.0 -67500.0 -0.71 -0.7373 -0.9422 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J17 compound treatment 382620.0 -21800.0 -0.22 293410.0 -102000.0 -1.07 -0.915 -0.8355 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J18 compound treatment 389510.0 -14900.0 -0.15 351630.0 -44200.0 -0.46 -0.4342 -0.892 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J19 compound treatment 382440.0 -22000.0 -0.22 368520.0 -27300.0 -0.29 -0.3598 -0.9926 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J20 compound treatment 381720.0 -22700.0 -0.23 325370.0 -70400.0 -0.74 -0.6847 -0.8859 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J21 mock treatment 455260.0 50800.0 0.52 406090.0 10300.0 0.11 0.4418 0.8368 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J22 mock treatment 380370.0 -24000.0 -0.24 364050.0 -31700.0 -0.33 -0.4078 -0.9885 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J23 compound treatment 405410.0 999.0 0.01 385520.0 -10300.0 -0.11 -0.0688 -0.6375 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 J24 compound treatment 337340.0 -67100.0 -0.68 325850.0 -69900.0 -0.73 -1.0001 -0.9993 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K01 compound treatment 311920.0 -92500.0 -0.94 365010.0 -30800.0 -0.32 -0.8926 -0.8983 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K02 compound treatment 393730.0 -10700.0 -0.11 401130.0 5350.0 0.06 -0.0371 -0.3039 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K03 compound treatment 376610.0 -27800.0 -0.28 409090.0 13300.0 0.14 -0.1012 -0.3211 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K04 compound treatment 370090.0 -34300.0 -0.35 416240.0 20500.0 0.21 -0.095 -0.2322 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K05 compound treatment 388340.0 -16100.0 -0.16 335360.0 -60400.0 -0.63 -0.5631 -0.8613 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K06 compound treatment 360000.0 -44400.0 -0.45 366940.0 -28800.0 -0.3 -0.5328 -0.981 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K07 mock treatment 368260.0 -36200.0 -0.37 447300.0 51500.0 0.54 0.1219 0.1867 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K08 mock treatment 472660.0 68200.0 0.69 305830.0 -90000.0 -0.94 -0.176 -0.1504 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K09 compound treatment 324960.0 -79500.0 -0.81 359170.0 -36600.0 -0.38 -0.8422 -0.9421 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K10 compound treatment 333010.0 -71400.0 -0.73 416480.0 20700.0 0.22 -0.3597 -0.475 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K11 compound treatment 396210.0 -8200.0 -0.08 387050.0 -8730.0 -0.09 -0.1236 -0.9989 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K12 compound treatment 378440.0 -26000.0 -0.26 335110.0 -60700.0 -0.64 -0.6361 -0.9242 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K13 compound treatment 369640.0 -34800.0 -0.35 354090.0 -41700.0 -0.44 -0.5587 -0.9945 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K14 compound treatment 385390.0 -19000.0 -0.19 317640.0 -78100.0 -0.82 -0.7156 -0.8507 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K15 mock treatment 425970.0 21600.0 0.22 393800.0 -1980.0 -0.02 0.1402 0.6373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K16 mock treatment 389190.0 -15200.0 -0.15 402400.0 6620.0 0.07 -0.0603 -0.3559 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K17 compound treatment 408550.0 4140.0 0.04 310520.0 -85300.0 -0.89 -0.6019 -0.6731 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K18 compound treatment 406570.0 2160.0 0.02 399680.0 3900.0 0.04 0.0444 0.9575 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K19 compound treatment 403950.0 -461.0 0.0 412410.0 16600.0 0.17 0.1199 0.6879 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K20 compound treatment 373600.0 -30800.0 -0.31 368270.0 -27500.0 -0.29 -0.4252 -0.9991 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K21 compound treatment 389680.0 -14700.0 -0.15 373550.0 -22200.0 -0.23 -0.2706 -0.9771 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K22 compound treatment 431480.0 27100.0 0.28 372800.0 -23000.0 -0.24 0.0243 0.0663 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K23 mock treatment 454140.0 49700.0 0.51 412710.0 16900.0 0.18 0.4828 0.9014 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 K24 mock treatment 403930.0 -481.0 0.0 379840.0 -15900.0 -0.17 -0.1216 -0.7275 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L01 compound treatment 475150.0 70700.0 0.72 426670.0 30900.0 0.32 0.7372 0.9351 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L02 compound treatment 214980.0 -189000.0 -1.93 216850.0 -179000.0 -1.87 -2.6868 -0.9999 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L03 compound treatment 288050.0 -116000.0 -1.18 286260.0 -110000.0 -1.15 -1.6475 -0.9999 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L04 compound treatment 329920.0 -74500.0 -0.76 341850.0 -53900.0 -0.57 -0.9348 -0.9896 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L05 compound treatment 316830.0 -87600.0 -0.89 348560.0 -47200.0 -0.49 -0.9792 -0.9616 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L06 compound treatment 351050.0 -53400.0 -0.54 277130.0 -119000.0 -1.24 -1.2625 -0.9308 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L07 mock treatment 371420.0 -33000.0 -0.34 417650.0 21900.0 0.23 -0.075 -0.1848 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L08 mock treatment 475770.0 71400.0 0.73 411470.0 15700.0 0.16 0.629 0.8459 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L09 compound treatment 370130.0 -34300.0 -0.35 299450.0 -96300.0 -1.01 -0.96 -0.8991 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L10 compound treatment 275050.0 -129000.0 -1.31 263250.0 -133000.0 -1.39 -1.9114 -0.9996 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L11 compound treatment 437320.0 32900.0 0.33 378850.0 -16900.0 -0.18 0.111 0.2933 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L12 compound treatment 382050.0 -22400.0 -0.23 370560.0 -25200.0 -0.26 -0.3475 -0.9972 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L13 compound treatment 429060.0 24600.0 0.25 388120.0 -7660.0 -0.08 0.1204 0.4576 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L14 compound treatment 389380.0 -15000.0 -0.15 389400.0 -6380.0 -0.07 -0.1553 -0.9313 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L15 mock treatment 410110.0 5700.0 0.06 397460.0 1680.0 0.02 0.0534 0.8821 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L16 mock treatment 387300.0 -17100.0 -0.17 392170.0 -3610.0 -0.04 -0.1497 -0.8413 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L17 compound treatment 240040.0 -164000.0 -1.67 221230.0 -175000.0 -1.83 -2.4743 -0.999 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L18 compound treatment 430000.0 25600.0 0.26 363050.0 -32700.0 -0.34 -0.0586 -0.1362 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L19 compound treatment 469440.0 65000.0 0.66 398630.0 2850.0 0.03 0.4884 0.7383 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L20 compound treatment 357090.0 -47300.0 -0.48 338600.0 -57200.0 -0.6 -0.7637 -0.9941 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L21 compound treatment 364030.0 -40400.0 -0.41 429650.0 33900.0 0.35 -0.0392 -0.0723 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L22 compound treatment 379530.0 -24900.0 -0.25 405400.0 9620.0 0.1 -0.1075 -0.395 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L23 mock treatment 464840.0 60400.0 0.61 469500.0 73700.0 0.77 0.9804 0.9935 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 L24 mock treatment 430560.0 26100.0 0.27 459680.0 63900.0 0.67 0.6613 0.9181 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M01 compound treatment 269570.0 -135000.0 -1.37 267050.0 -129000.0 -1.35 -1.9227 -1.0 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M02 compound treatment 409020.0 4610.0 0.05 409440.0 13700.0 0.14 0.1343 0.892 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M03 compound treatment 340350.0 -64100.0 -0.65 302730.0 -93100.0 -0.97 -1.1497 -0.9807 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M04 compound treatment 390080.0 -14300.0 -0.15 323400.0 -72400.0 -0.76 -0.6392 -0.8278 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M05 compound treatment 438730.0 34300.0 0.35 323800.0 -72000.0 -0.75 -0.2867 -0.345 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M06 compound treatment 382880.0 -21500.0 -0.22 397850.0 2070.0 0.02 -0.1394 -0.6339 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M07 compound treatment 241790.0 -163000.0 -1.65 294530.0 -101000.0 -1.06 -1.9187 -0.977 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M08 compound treatment 289340.0 -115000.0 -1.17 262250.0 -134000.0 -1.4 -1.8162 -0.996 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M09 mock treatment 426180.0 21800.0 0.22 425410.0 29600.0 0.31 0.3759 0.9862 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M10 mock treatment 461230.0 56800.0 0.58 405210.0 9430.0 0.1 0.4781 0.8162 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M11 compound treatment 304930.0 -99500.0 -1.01 276560.0 -119000.0 -1.25 -1.5981 -0.9945 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M12 compound treatment 466810.0 62400.0 0.63 368040.0 -27700.0 -0.29 0.2429 0.3482 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M13 mock treatment 446240.0 41800.0 0.43 375270.0 -20500.0 -0.21 0.1486 0.312 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M14 mock treatment 429370.0 25000.0 0.25 446460.0 50700.0 0.53 0.5548 0.9428 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M15 compound treatment 365970.0 -38400.0 -0.39 337500.0 -58300.0 -0.61 -0.708 -0.9767 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M16 compound treatment 289280.0 -115000.0 -1.17 263760.0 -132000.0 -1.38 -1.8054 -0.9965 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M17 compound treatment 314080.0 -90300.0 -0.92 304610.0 -91200.0 -0.96 -1.3246 -0.9998 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M18 compound treatment 386820.0 -17600.0 -0.18 374560.0 -21200.0 -0.22 -0.2836 -0.9941 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M19 compound treatment 353440.0 -51000.0 -0.52 318160.0 -77600.0 -0.81 -0.9413 -0.9763 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M20 compound treatment 382080.0 -22300.0 -0.23 346170.0 -49600.0 -0.52 -0.528 -0.931 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M21 compound treatment 348860.0 -55600.0 -0.56 336880.0 -58900.0 -0.62 -0.8356 -0.999 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M22 compound treatment 392870.0 -11500.0 -0.12 354720.0 -41100.0 -0.43 -0.3871 -0.8682 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M23 compound treatment 335960.0 -68500.0 -0.7 364810.0 -31000.0 -0.32 -0.7213 -0.9397 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 M24 compound treatment 390900.0 -13500.0 -0.14 376320.0 -19500.0 -0.2 -0.2413 -0.9815 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N01 compound treatment 391120.0 -13300.0 -0.14 440640.0 44900.0 0.47 0.2368 0.4843 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N02 compound treatment 479300.0 74900.0 0.76 385340.0 -10400.0 -0.11 0.4608 0.5993 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N03 compound treatment 464030.0 59600.0 0.61 405120.0 9340.0 0.1 0.4976 0.8108 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N04 compound treatment 422830.0 18400.0 0.19 472840.0 77100.0 0.81 0.7033 0.8485 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N05 compound treatment 363610.0 -40800.0 -0.41 358770.0 -37000.0 -0.39 -0.5674 -0.9994 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N06 compound treatment 438400.0 34000.0 0.35 408340.0 12600.0 0.13 0.3373 0.9125 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N07 compound treatment 299790.0 -105000.0 -1.06 380240.0 -15500.0 -0.16 -0.8669 -0.806 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N08 compound treatment 390340.0 -14100.0 -0.14 427860.0 32100.0 0.34 0.1366 0.3739 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N09 mock treatment 410720.0 6310.0 0.06 373510.0 -22300.0 -0.23 -0.1197 -0.4945 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N10 mock treatment 404080.0 -331.0 0.0 347740.0 -48000.0 -0.5 -0.3583 -0.7118 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N11 compound treatment 419640.0 15200.0 0.15 370630.0 -25200.0 -0.26 -0.0769 -0.2516 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N12 compound treatment 431530.0 27100.0 0.28 335900.0 -59900.0 -0.63 -0.2488 -0.363 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N13 mock treatment 402400.0 -2010.0 -0.02 387390.0 -8390.0 -0.09 -0.0766 -0.8488 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N14 mock treatment 469560.0 65100.0 0.66 486240.0 90500.0 0.95 1.1383 0.9846 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N15 compound treatment 457350.0 52900.0 0.54 393250.0 -2530.0 -0.03 0.3617 0.6714 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N16 compound treatment 408010.0 3600.0 0.04 418680.0 22900.0 0.24 0.1955 0.8056 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N17 compound treatment 452000.0 47600.0 0.48 375620.0 -20200.0 -0.21 0.1926 0.3649 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N18 compound treatment 385060.0 -19400.0 -0.2 328320.0 -67500.0 -0.71 -0.6388 -0.8708 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N19 compound treatment 445300.0 40900.0 0.42 399060.0 3280.0 0.03 0.3181 0.763 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N20 compound treatment 310310.0 -94100.0 -0.96 284160.0 -112000.0 -1.17 -1.5031 -0.995 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N21 compound treatment 426240.0 21800.0 0.22 403290.0 7510.0 0.08 0.2125 0.9028 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N22 compound treatment 343850.0 -60600.0 -0.62 313760.0 -82000.0 -0.86 -1.0428 -0.9866 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N23 compound treatment 379110.0 -25300.0 -0.26 349850.0 -45900.0 -0.48 -0.5221 -0.9569 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 N24 compound treatment 393990.0 -10400.0 -0.11 416550.0 20800.0 0.22 0.079 0.3264 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O01 compound treatment 131750.0 -273000.0 -2.77 276970.0 -119000.0 -1.24 -2.8395 -0.9348 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O02 compound treatment 302820.0 -102000.0 -1.03 342080.0 -53700.0 -0.56 -1.1279 -0.9593 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O03 compound treatment 506130.0 102000.0 1.03 304130.0 -91700.0 -0.96 0.0519 0.0368 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O04 compound treatment 386720.0 -17700.0 -0.18 351220.0 -44600.0 -0.47 -0.4573 -0.914 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O05 compound treatment 381850.0 -22600.0 -0.23 253130.0 -143000.0 -1.49 -1.219 -0.8061 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O06 compound treatment 284330.0 -120000.0 -1.22 329770.0 -66000.0 -0.69 -1.3519 -0.9638 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O07 compound treatment 378930.0 -25500.0 -0.26 252040.0 -144000.0 -1.51 -1.248 -0.8167 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O08 compound treatment 367750.0 -36700.0 -0.37 394940.0 -841.0 -0.01 -0.2697 -0.7236 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O09 compound treatment 344480.0 -59900.0 -0.61 331000.0 -64800.0 -0.68 -0.9106 -0.9985 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O10 compound treatment 307790.0 -96600.0 -0.98 405650.0 9870.0 0.1 -0.6212 -0.6292 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O11 mock treatment 392000.0 -12400.0 -0.13 448810.0 53000.0 0.56 0.3037 0.533 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O12 mock treatment 298360.0 -106000.0 -1.08 371790.0 -24000.0 -0.25 -0.9398 -0.8492 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O13 compound treatment 391680.0 -12700.0 -0.13 384010.0 -11800.0 -0.12 -0.1787 -0.9997 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O14 compound treatment 349380.0 -55000.0 -0.56 413650.0 17900.0 0.19 -0.263 -0.446 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O15 compound treatment 377340.0 -27100.0 -0.28 403730.0 7950.0 0.08 -0.1356 -0.4719 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O16 compound treatment 353780.0 -50600.0 -0.51 366190.0 -29600.0 -0.31 -0.583 -0.9706 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O17 compound treatment 290280.0 -114000.0 -1.16 330160.0 -65600.0 -0.69 -1.3063 -0.9688 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O18 compound treatment 302850.0 -102000.0 -1.03 374760.0 -21000.0 -0.22 -0.8855 -0.8391 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O19 compound treatment 331800.0 -72600.0 -0.74 412640.0 16900.0 0.18 -0.3969 -0.5231 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O20 compound treatment 364920.0 -39500.0 -0.4 408960.0 13200.0 0.14 -0.1861 -0.4386 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O21 compound treatment 326300.0 -78100.0 -0.79 390510.0 -5270.0 -0.06 -0.6003 -0.7545 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O22 compound treatment 257330.0 -147000.0 -1.49 329950.0 -65800.0 -0.69 -1.5446 -0.9383 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O23 compound treatment 350080.0 -54300.0 -0.55 266310.0 -129000.0 -1.36 -1.3496 -0.9215 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 O24 compound treatment 358990.0 -45400.0 -0.46 301560.0 -94200.0 -0.99 -1.0244 -0.94 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P01 compound treatment 307950.0 -96500.0 -0.98 275690.0 -120000.0 -1.26 -1.5829 -0.9924 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P02 compound treatment 361840.0 -42600.0 -0.43 370150.0 -25600.0 -0.27 -0.4958 -0.9737 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P03 compound treatment 338210.0 -66200.0 -0.67 379840.0 -15900.0 -0.17 -0.5938 -0.8567 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P04 compound treatment 401670.0 -2740.0 -0.03 407290.0 11500.0 0.12 0.0656 0.5298 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P05 compound treatment 283890.0 -121000.0 -1.22 389060.0 -6720.0 -0.07 -0.9158 -0.7465 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P06 compound treatment 311910.0 -92500.0 -0.94 395680.0 -101.0 0.0 -0.6654 -0.7079 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P07 compound treatment 351520.0 -52900.0 -0.54 346470.0 -49300.0 -0.52 -0.7454 -0.9998 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P08 compound treatment 228490.0 -176000.0 -1.79 242440.0 -153000.0 -1.61 -2.4002 -0.9986 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P09 compound treatment 345280.0 -59100.0 -0.6 369150.0 -26600.0 -0.28 -0.6222 -0.9391 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P10 compound treatment 323900.0 -80500.0 -0.82 290120.0 -106000.0 -1.11 -1.3613 -0.9889 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P11 mock treatment 363360.0 -41100.0 -0.42 342340.0 -53400.0 -0.56 -0.6909 -0.9895 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P12 mock treatment 372890.0 -31500.0 -0.32 407840.0 12100.0 0.13 -0.1372 -0.3983 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P13 compound treatment 362560.0 -41900.0 -0.43 370830.0 -25000.0 -0.26 -0.4856 -0.9727 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P14 compound treatment 393140.0 -11300.0 -0.11 344340.0 -51400.0 -0.54 -0.4621 -0.8386 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P15 compound treatment 341030.0 -63400.0 -0.64 367390.0 -28400.0 -0.3 -0.6658 -0.9384 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P16 compound treatment 391240.0 -13200.0 -0.13 339140.0 -56600.0 -0.59 -0.5143 -0.8453 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P17 compound treatment 348920.0 -55500.0 -0.56 392060.0 -3720.0 -0.04 -0.4263 -0.7542 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P18 compound treatment 351870.0 -52500.0 -0.53 327150.0 -68600.0 -0.72 -0.886 -0.9893 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P19 compound treatment 369670.0 -34700.0 -0.35 384850.0 -10900.0 -0.11 -0.3306 -0.8908 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P20 compound treatment 334090.0 -70300.0 -0.71 328930.0 -66900.0 -0.7 -1.0006 -0.9999 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P21 compound treatment 388710.0 -15700.0 -0.16 310880.0 -84900.0 -0.89 -0.7418 -0.8208 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P22 compound treatment 333190.0 -71200.0 -0.72 341880.0 -53900.0 -0.56 -0.9111 -0.9925 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P23 compound treatment 390960.0 -13500.0 -0.14 380000.0 -15800.0 -0.17 -0.2136 -0.9955 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2094 P24 compound treatment 346930.0 -57500.0 -0.58 365950.0 -29800.0 -0.31 -0.634 -0.9571 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A01 compound treatment 447710.0 -22400.0 -0.23 417330.0 -37300.0 -0.39 -0.4371 -0.9667 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A02 compound treatment 516660.0 46600.0 0.47 410740.0 -43900.0 -0.46 0.0095 0.0144 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A03 compound treatment 459150.0 -10900.0 -0.11 398370.0 -56300.0 -0.59 -0.4954 -0.8257 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A04 compound treatment 348890.0 -121000.0 -1.23 224020.0 -231000.0 -2.42 -2.5794 -0.9511 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A05 compound treatment 338470.0 -132000.0 -1.34 347780.0 -107000.0 -1.12 -1.7374 -0.9961 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A06 compound treatment 443120.0 -26900.0 -0.27 339430.0 -115000.0 -1.21 -1.0473 -0.846 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A07 compound treatment 377840.0 -92200.0 -0.94 455480.0 832.0 0.01 -0.6566 -0.7005 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A08 compound treatment 352530.0 -118000.0 -1.19 287860.0 -167000.0 -1.75 -2.0803 -0.9828 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A09 compound treatment 421930.0 -48100.0 -0.49 411750.0 -42900.0 -0.45 -0.6637 -0.9991 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A10 compound treatment 456440.0 -13600.0 -0.14 413810.0 -40800.0 -0.43 -0.4005 -0.8905 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A11 compound treatment 364500.0 -106000.0 -1.07 312390.0 -142000.0 -1.49 -1.8125 -0.987 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A12 compound treatment 434300.0 -35800.0 -0.36 371040.0 -83600.0 -0.88 -0.8765 -0.9241 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A13 mock treatment 349530.0 -121000.0 -1.22 403520.0 -51100.0 -0.54 -1.245 -0.9312 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A14 mock treatment 478880.0 8810.0 0.09 373360.0 -81300.0 -0.85 -0.5389 -0.6293 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A15 compound treatment 385070.0 -85000.0 -0.86 318190.0 -136000.0 -1.43 -1.6218 -0.9709 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A16 compound treatment 347120.0 -123000.0 -1.25 369410.0 -85200.0 -0.89 -1.515 -0.9864 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A17 compound treatment 458620.0 -11400.0 -0.12 439520.0 -15100.0 -0.16 -0.1944 -0.9884 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A18 compound treatment 472730.0 2660.0 0.03 429410.0 -25200.0 -0.26 -0.1679 -0.6315 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A19 compound treatment 376190.0 -93900.0 -0.95 390750.0 -63900.0 -0.67 -1.148 -0.985 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A20 compound treatment 313140.0 -157000.0 -1.59 268170.0 -186000.0 -1.95 -2.5092 -0.9949 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A21 compound treatment 246240.0 -224000.0 -2.27 216030.0 -239000.0 -2.5 -3.3762 -0.9989 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A22 compound treatment 407200.0 -62900.0 -0.64 309680.0 -145000.0 -1.52 -1.5258 -0.926 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A23 compound treatment 359840.0 -110000.0 -1.12 405180.0 -49500.0 -0.52 -1.1586 -0.9387 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 A24 compound treatment 409030.0 -61000.0 -0.62 407810.0 -46800.0 -0.49 -0.7856 -0.9933 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B01 compound treatment 233230.0 -237000.0 -2.41 244820.0 -210000.0 -2.2 -3.2564 -0.999 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B02 compound treatment 472660.0 2590.0 0.03 470310.0 15700.0 0.16 0.1347 0.8102 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B03 compound treatment 560850.0 90800.0 0.92 502080.0 47400.0 0.5 1.0037 0.9579 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B04 compound treatment 488580.0 18500.0 0.19 418610.0 -36000.0 -0.38 -0.134 -0.3176 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B05 compound treatment 532660.0 62600.0 0.64 461560.0 6910.0 0.07 0.501 0.7826 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B06 compound treatment 468480.0 -1590.0 -0.02 431060.0 -23600.0 -0.25 -0.1862 -0.7517 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B07 compound treatment 473550.0 3480.0 0.04 485890.0 31200.0 0.33 0.2565 0.779 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B08 compound treatment 219240.0 -251000.0 -2.55 287310.0 -167000.0 -1.75 -3.0421 -0.9833 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B09 compound treatment 409860.0 -60200.0 -0.61 436260.0 -18400.0 -0.19 -0.5689 -0.8868 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B10 compound treatment 321390.0 -149000.0 -1.51 297920.0 -157000.0 -1.64 -2.2295 -0.9991 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B11 compound treatment 458640.0 -11400.0 -0.12 474400.0 19800.0 0.21 0.0642 0.2706 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B12 compound treatment 402030.0 -68000.0 -0.69 321760.0 -133000.0 -1.39 -1.4734 -0.9478 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B13 mock treatment 438530.0 -31500.0 -0.32 511620.0 57000.0 0.6 0.1955 0.2885 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B14 mock treatment 426040.0 -44000.0 -0.45 458620.0 3970.0 0.04 -0.287 -0.6386 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B15 compound treatment 475680.0 5610.0 0.06 486000.0 31400.0 0.33 0.2726 0.8176 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B16 compound treatment 445290.0 -24800.0 -0.25 337020.0 -118000.0 -1.23 -1.0495 -0.8343 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B17 compound treatment 474290.0 4220.0 0.04 453050.0 -1600.0 -0.02 0.0185 0.4016 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B18 compound treatment 500000.0 29900.0 0.3 479010.0 24400.0 0.26 0.3956 0.9962 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B19 compound treatment 332270.0 -138000.0 -1.4 271900.0 -183000.0 -1.91 -2.3441 -0.9882 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B20 compound treatment 401890.0 -68200.0 -0.69 396590.0 -58100.0 -0.61 -0.9201 -0.9979 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B21 compound treatment 435520.0 -34500.0 -0.35 461550.0 6900.0 0.07 -0.1971 -0.5499 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B22 compound treatment 411750.0 -58300.0 -0.59 438360.0 -16300.0 -0.17 -0.5397 -0.8752 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B23 compound treatment 419610.0 -50500.0 -0.51 401660.0 -53000.0 -0.56 -0.7552 -0.9992 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 B24 compound treatment 412040.0 -58000.0 -0.59 382900.0 -71700.0 -0.75 -0.9485 -0.9928 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C01 compound treatment 443840.0 -26200.0 -0.27 459380.0 4730.0 0.05 -0.1534 -0.5659 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C02 compound treatment 431580.0 -38500.0 -0.39 329490.0 -125000.0 -1.31 -1.2038 -0.8797 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C03 compound treatment 432990.0 -37100.0 -0.38 337210.0 -117000.0 -1.23 -1.1365 -0.8832 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C04 compound treatment 20080.0 -450000.0 -4.57 15110.0 -440000.0 -4.61 -6.4899 -1.0 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C05 compound treatment 359060.0 -111000.0 -1.13 420160.0 -34500.0 -0.36 -1.0532 -0.8891 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C06 compound treatment 455090.0 -15000.0 -0.15 340200.0 -114000.0 -1.2 -0.9556 -0.7905 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C07 compound treatment 423780.0 -46300.0 -0.47 436640.0 -18000.0 -0.19 -0.466 -0.9195 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C08 compound treatment 233280.0 -237000.0 -2.41 257550.0 -197000.0 -2.07 -3.1617 -0.9971 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C09 compound treatment 389680.0 -80400.0 -0.82 398400.0 -56200.0 -0.59 -0.9944 -0.9872 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C10 compound treatment 225970.0 -244000.0 -2.48 142190.0 -312000.0 -3.27 -4.0689 -0.9906 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C11 mock treatment 441310.0 -28800.0 -0.29 490950.0 36300.0 0.38 0.0623 0.1299 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C12 mock treatment 447740.0 -22300.0 -0.23 430780.0 -23900.0 -0.25 -0.3373 -0.9988 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C13 compound treatment 372330.0 -97700.0 -0.99 363200.0 -91400.0 -0.96 -1.3798 -0.9998 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C14 compound treatment 419040.0 -51000.0 -0.52 341200.0 -113000.0 -1.19 -1.2072 -0.9309 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C15 mock treatment 430250.0 -39800.0 -0.4 407920.0 -46700.0 -0.49 -0.6323 -0.9955 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C16 mock treatment 352330.0 -118000.0 -1.2 408260.0 -46400.0 -0.49 -1.1897 -0.9212 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C17 compound treatment 299450.0 -171000.0 -1.73 411850.0 -42800.0 -0.45 -1.5431 -0.8616 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C18 compound treatment 330810.0 -139000.0 -1.42 253550.0 -201000.0 -2.11 -2.4906 -0.9812 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C19 compound treatment 395290.0 -74800.0 -0.76 415440.0 -39200.0 -0.41 -0.8278 -0.9583 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C20 compound treatment 366300.0 -104000.0 -1.05 382520.0 -72100.0 -0.76 -1.28 -0.9867 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C21 compound treatment 277720.0 -192000.0 -1.95 345210.0 -109000.0 -1.15 -2.193 -0.9677 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C22 compound treatment 382170.0 -87900.0 -0.89 355160.0 -99500.0 -1.04 -1.3687 -0.997 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C23 compound treatment 371760.0 -98300.0 -1.0 364510.0 -90100.0 -0.94 -1.3742 -0.9996 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 C24 compound treatment 405130.0 -64900.0 -0.66 432120.0 -22500.0 -0.24 -0.6335 -0.9039 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D01 compound treatment 382750.0 -87300.0 -0.89 462210.0 7560.0 0.08 -0.5714 -0.6414 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D02 compound treatment 250800.0 -219000.0 -2.23 243750.0 -211000.0 -2.21 -3.1381 -1.0 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D03 compound treatment 445720.0 -24300.0 -0.25 435940.0 -18700.0 -0.2 -0.3136 -0.9933 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D04 compound treatment 570050.0 100000.0 1.02 447600.0 -7050.0 -0.07 0.6662 0.654 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D05 compound treatment 504130.0 34100.0 0.35 455460.0 812.0 0.01 0.2508 0.7243 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D06 compound treatment 286880.0 -183000.0 -1.86 280320.0 -174000.0 -1.83 -2.6079 -1.0 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D07 compound treatment 428050.0 -42000.0 -0.43 395360.0 -59300.0 -0.62 -0.7412 -0.9833 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D08 compound treatment 455770.0 -14300.0 -0.15 420550.0 -34100.0 -0.36 -0.3554 -0.9214 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D09 compound treatment 413210.0 -56900.0 -0.58 411680.0 -43000.0 -0.45 -0.7269 -0.9924 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D10 compound treatment 270670.0 -199000.0 -2.03 264980.0 -190000.0 -1.99 -2.838 -1.0 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D11 mock treatment 490400.0 20300.0 0.21 462240.0 7590.0 0.08 0.2023 0.914 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D12 mock treatment 384510.0 -85600.0 -0.87 445190.0 -9460.0 -0.1 -0.6849 -0.7826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D13 compound treatment 421510.0 -48600.0 -0.49 464560.0 9910.0 0.1 -0.2755 -0.5463 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D14 compound treatment 515200.0 45100.0 0.46 404910.0 -49700.0 -0.52 -0.0442 -0.0637 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D15 mock treatment 509780.0 39700.0 0.4 432370.0 -22300.0 -0.23 0.1203 0.258 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D16 mock treatment 536870.0 66800.0 0.68 435450.0 -19200.0 -0.2 0.3378 0.4771 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D17 compound treatment 380750.0 -89300.0 -0.91 436320.0 -18300.0 -0.19 -0.7776 -0.8382 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D18 compound treatment 349850.0 -120000.0 -1.22 346150.0 -108000.0 -1.14 -1.6677 -0.9994 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D19 compound treatment 396800.0 -73300.0 -0.74 390120.0 -64500.0 -0.68 -1.0046 -0.9988 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D20 compound treatment 426890.0 -43200.0 -0.44 356020.0 -98600.0 -1.03 -1.041 -0.9272 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D21 compound treatment 428610.0 -41500.0 -0.42 403640.0 -51000.0 -0.53 -0.6758 -0.9931 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D22 compound treatment 236800.0 -233000.0 -2.37 255440.0 -199000.0 -2.09 -3.1521 -0.998 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D23 compound treatment 447320.0 -22700.0 -0.23 412870.0 -41800.0 -0.44 -0.473 -0.9555 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 D24 compound treatment 227260.0 -243000.0 -2.47 224570.0 -230000.0 -2.41 -3.4493 -0.9999 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E01 mock treatment 448260.0 -21800.0 -0.22 460320.0 5670.0 0.06 -0.1147 -0.4998 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E02 mock treatment 508640.0 38600.0 0.39 475590.0 20900.0 0.22 0.4323 0.9624 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E03 compound treatment 467620.0 -2450.0 -0.02 460580.0 5930.0 0.06 0.0263 0.3935 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E04 compound treatment 463110.0 -6960.0 -0.07 441460.0 -13200.0 -0.14 -0.1477 -0.9516 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E05 compound treatment 431080.0 -39000.0 -0.4 371160.0 -83500.0 -0.87 -0.8987 -0.9359 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E06 compound treatment 423130.0 -46900.0 -0.48 292930.0 -162000.0 -1.69 -1.5354 -0.8723 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E07 compound treatment 475910.0 5840.0 0.06 439300.0 -15300.0 -0.16 -0.0717 -0.4185 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E08 compound treatment 505530.0 35500.0 0.36 483300.0 28700.0 0.3 0.4671 0.9959 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E09 mock treatment 528810.0 58700.0 0.6 345440.0 -109000.0 -1.14 -0.387 -0.2999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E10 mock treatment 510740.0 40700.0 0.41 509940.0 55300.0 0.58 0.7019 0.9863 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E11 compound treatment 421360.0 -48700.0 -0.49 441280.0 -13400.0 -0.14 -0.449 -0.8729 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E12 compound treatment 346560.0 -124000.0 -1.26 375080.0 -79600.0 -0.83 -1.477 -0.9802 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E13 compound treatment 473780.0 3710.0 0.04 515450.0 60800.0 0.64 0.4771 0.7477 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E14 compound treatment 441310.0 -28800.0 -0.29 497880.0 43200.0 0.45 0.1136 0.2108 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E15 compound treatment 363070.0 -107000.0 -1.09 349090.0 -106000.0 -1.11 -1.5509 -1.0 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E16 compound treatment 460390.0 -9680.0 -0.1 433870.0 -20800.0 -0.22 -0.2235 -0.9355 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E17 mock treatment 501670.0 31600.0 0.32 479060.0 24400.0 0.26 0.4079 0.9936 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E18 mock treatment 468800.0 -1270.0 -0.01 490490.0 35800.0 0.38 0.2564 0.6824 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E19 compound treatment 437410.0 -32700.0 -0.33 447710.0 -6940.0 -0.07 -0.2861 -0.842 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E20 compound treatment 468410.0 -1660.0 -0.02 393530.0 -61100.0 -0.64 -0.4647 -0.7255 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E21 compound treatment 423280.0 -46800.0 -0.48 445150.0 -9500.0 -0.1 -0.4066 -0.837 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E22 compound treatment 443390.0 -26700.0 -0.27 424000.0 -30600.0 -0.32 -0.4188 -0.9965 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E23 compound treatment 375450.0 -94600.0 -0.96 404000.0 -50600.0 -0.53 -1.0551 -0.9608 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 E24 compound treatment 415000.0 -55100.0 -0.56 370690.0 -84000.0 -0.88 -1.0177 -0.9762 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F01 mock treatment 490260.0 20200.0 0.21 421380.0 -33300.0 -0.35 -0.1014 -0.2507 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F02 mock treatment 492420.0 22400.0 0.23 497440.0 42800.0 0.45 0.4776 0.9503 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F03 compound treatment 355760.0 -114000.0 -1.16 396530.0 -58100.0 -0.61 -1.252 -0.9546 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F04 compound treatment 346950.0 -123000.0 -1.25 403060.0 -51600.0 -0.54 -1.2669 -0.9296 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F05 compound treatment 467870.0 -2200.0 -0.02 369920.0 -84700.0 -0.89 -0.6435 -0.7247 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F06 compound treatment 464650.0 -5420.0 -0.06 513010.0 58400.0 0.61 0.3934 0.6408 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F07 compound treatment 273660.0 -196000.0 -2.0 237440.0 -217000.0 -2.28 -3.0206 -0.9979 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F08 compound treatment 381040.0 -89000.0 -0.9 417410.0 -37200.0 -0.39 -0.9156 -0.9293 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F09 mock treatment 318800.0 -151000.0 -1.54 333660.0 -121000.0 -1.27 -1.9833 -0.9954 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F10 mock treatment 427540.0 -42500.0 -0.43 467210.0 12600.0 0.13 -0.2125 -0.4704 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F11 compound treatment 399360.0 -70700.0 -0.72 465070.0 10400.0 0.11 -0.4309 -0.5928 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F12 compound treatment 258240.0 -212000.0 -2.15 261610.0 -193000.0 -2.02 -2.9523 -0.9995 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F13 compound treatment 537530.0 67500.0 0.69 428380.0 -26300.0 -0.28 0.2901 0.3928 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F14 compound treatment 483040.0 13000.0 0.13 488280.0 33600.0 0.35 0.3424 0.91 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F15 compound treatment 427960.0 -42100.0 -0.43 375090.0 -79600.0 -0.83 -0.892 -0.952 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F16 compound treatment 377920.0 -92100.0 -0.94 402030.0 -52600.0 -0.55 -1.052 -0.9681 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F17 mock treatment 406750.0 -63300.0 -0.64 465410.0 10800.0 0.11 -0.3753 -0.5744 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F18 mock treatment 473760.0 3690.0 0.04 410740.0 -43900.0 -0.46 -0.2988 -0.6473 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F19 compound treatment 378460.0 -91600.0 -0.93 295540.0 -159000.0 -1.67 -1.8371 -0.9621 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F20 compound treatment 246730.0 -223000.0 -2.27 282530.0 -172000.0 -1.8 -2.88 -0.9935 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F21 compound treatment 374940.0 -95100.0 -0.97 364490.0 -90200.0 -0.94 -1.3515 -0.9999 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F22 compound treatment 204640.0 -265000.0 -2.7 228870.0 -226000.0 -2.37 -3.58 -0.9979 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F23 compound treatment 447690.0 -22400.0 -0.23 376480.0 -78200.0 -0.82 -0.7399 -0.8705 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 F24 compound treatment 420980.0 -49100.0 -0.5 336060.0 -119000.0 -1.24 -1.2313 -0.9196 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G01 compound treatment 324080.0 -146000.0 -1.48 347260.0 -107000.0 -1.13 -1.8446 -0.9907 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G02 compound treatment 472800.0 2730.0 0.03 535610.0 81000.0 0.85 0.6194 0.7298 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G03 mock treatment 377600.0 -92500.0 -0.94 412480.0 -42200.0 -0.44 -0.9769 -0.9408 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G04 mock treatment 518520.0 48500.0 0.49 511780.0 57100.0 0.6 0.7714 0.9953 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G05 compound treatment 559440.0 89400.0 0.91 482820.0 28200.0 0.3 0.8509 0.891 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G06 compound treatment 521120.0 51100.0 0.52 442480.0 -12200.0 -0.13 0.2767 0.5179 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G07 compound treatment 453360.0 -16700.0 -0.17 448710.0 -5940.0 -0.06 -0.1641 -0.9072 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G08 compound treatment 448500.0 -21600.0 -0.22 475080.0 20400.0 0.21 -0.0036 -0.0118 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G09 compound treatment 457630.0 -12400.0 -0.13 424920.0 -29700.0 -0.31 -0.3096 -0.9211 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G10 compound treatment 465070.0 -5000.0 -0.05 416600.0 -38000.0 -0.4 -0.3178 -0.7908 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G11 compound treatment 477550.0 7480.0 0.08 417640.0 -37000.0 -0.39 -0.2204 -0.5579 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G12 compound treatment 322360.0 -148000.0 -1.5 287710.0 -167000.0 -1.75 -2.2982 -0.9971 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G13 compound treatment 468490.0 -1580.0 -0.02 432220.0 -22400.0 -0.23 -0.1775 -0.7536 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G14 compound treatment 466460.0 -3610.0 -0.04 489350.0 34700.0 0.36 0.2312 0.6326 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G15 compound treatment 516320.0 46300.0 0.47 468960.0 14300.0 0.15 0.4384 0.8886 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G16 compound treatment 342590.0 -127000.0 -1.3 373940.0 -80700.0 -0.85 -1.514 -0.9786 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G17 compound treatment 392970.0 -77100.0 -0.78 386880.0 -67800.0 -0.71 -1.0561 -0.9988 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G18 compound treatment 243910.0 -226000.0 -2.3 251760.0 -203000.0 -2.13 -3.1283 -0.9992 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G19 mock treatment 501010.0 30900.0 0.31 450020.0 -4630.0 -0.05 0.188 0.5911 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G20 mock treatment 541560.0 71500.0 0.73 414170.0 -40500.0 -0.42 0.2138 0.2542 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G21 compound treatment 403010.0 -67100.0 -0.68 350780.0 -104000.0 -1.09 -1.2514 -0.9746 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G22 compound treatment 435460.0 -34600.0 -0.35 411310.0 -43300.0 -0.45 -0.5698 -0.992 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G23 compound treatment 452120.0 -17900.0 -0.18 346930.0 -108000.0 -1.13 -0.927 -0.8109 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 G24 compound treatment 391910.0 -78200.0 -0.79 393550.0 -61100.0 -0.64 -1.0143 -0.9943 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H01 compound treatment 364440.0 -106000.0 -1.07 451130.0 -3520.0 -0.04 -0.7851 -0.731 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H02 compound treatment 241150.0 -229000.0 -2.33 245720.0 -209000.0 -2.19 -3.1928 -0.9995 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H03 mock treatment 465140.0 -4930.0 -0.05 491390.0 36700.0 0.38 0.2368 0.61 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H04 mock treatment 539720.0 69700.0 0.71 501600.0 47000.0 0.49 0.8483 0.9842 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H05 compound treatment 385560.0 -84500.0 -0.86 378170.0 -76500.0 -0.8 -1.1739 -0.9994 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H06 compound treatment 288060.0 -182000.0 -1.85 250050.0 -205000.0 -2.14 -2.8237 -0.9973 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H07 compound treatment 475360.0 5290.0 0.05 462100.0 7450.0 0.08 0.0932 0.9834 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H08 compound treatment 502350.0 32300.0 0.33 470240.0 15600.0 0.16 0.3475 0.9482 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H09 compound treatment 406730.0 -63300.0 -0.64 506600.0 52000.0 0.54 -0.0702 -0.0833 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H10 compound treatment 456930.0 -13100.0 -0.13 351200.0 -103000.0 -1.08 -0.8608 -0.7883 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H11 compound treatment 415970.0 -54100.0 -0.55 407210.0 -47400.0 -0.5 -0.7402 -0.9987 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H12 compound treatment 532040.0 62000.0 0.63 377840.0 -76800.0 -0.8 -0.1237 -0.1211 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H13 compound treatment 440250.0 -29800.0 -0.3 388660.0 -66000.0 -0.69 -0.7032 -0.9315 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H14 compound treatment 454610.0 -15500.0 -0.16 453170.0 -1480.0 -0.02 -0.122 -0.7731 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H15 compound treatment 454240.0 -15800.0 -0.16 463360.0 8710.0 0.09 -0.0492 -0.266 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H16 compound treatment 412970.0 -57100.0 -0.58 480330.0 25700.0 0.27 -0.22 -0.344 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H17 compound treatment 519200.0 49100.0 0.5 500480.0 45800.0 0.48 0.6926 0.9998 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H18 compound treatment 498780.0 28700.0 0.29 467860.0 13200.0 0.14 0.3042 0.942 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H19 mock treatment 469570.0 -499.0 -0.01 442140.0 -12500.0 -0.13 -0.0963 -0.7339 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H20 mock treatment 490350.0 20300.0 0.21 469090.0 14400.0 0.15 0.2527 0.9885 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H21 compound treatment 415490.0 -54600.0 -0.55 435470.0 -19200.0 -0.2 -0.5343 -0.9057 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H22 compound treatment 226410.0 -244000.0 -2.48 261670.0 -193000.0 -2.02 -3.1806 -0.9949 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H23 compound treatment 400380.0 -69700.0 -0.71 419730.0 -34900.0 -0.37 -0.7595 -0.9528 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 H24 compound treatment 415130.0 -54900.0 -0.56 367760.0 -86900.0 -0.91 -1.0385 -0.9724 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I01 compound treatment 445660.0 -24400.0 -0.25 444690.0 -9960.0 -0.1 -0.2492 -0.926 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I02 compound treatment 450240.0 -19800.0 -0.2 392720.0 -61900.0 -0.65 -0.6013 -0.885 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I03 compound treatment 412710.0 -57400.0 -0.58 464440.0 9790.0 0.1 -0.3396 -0.5738 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I04 compound treatment 434330.0 -35700.0 -0.36 432690.0 -22000.0 -0.23 -0.4195 -0.9757 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I05 mock treatment 437140.0 -32900.0 -0.33 377380.0 -77300.0 -0.81 -0.8091 -0.9236 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I06 mock treatment 444480.0 -25600.0 -0.26 454620.0 -27.9 0.0 -0.1841 -0.7079 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I07 compound treatment 453960.0 -16100.0 -0.16 405470.0 -49200.0 -0.52 -0.4801 -0.888 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I08 compound treatment 515610.0 45500.0 0.46 483790.0 29100.0 0.31 0.5431 0.9796 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I09 compound treatment 302260.0 -168000.0 -1.71 248690.0 -206000.0 -2.16 -2.7317 -0.9932 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I10 compound treatment 418890.0 -51200.0 -0.52 511170.0 56500.0 0.59 0.051 0.0647 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I11 compound treatment 494810.0 24700.0 0.25 353940.0 -101000.0 -1.06 -0.5683 -0.524 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I12 compound treatment 472550.0 2480.0 0.03 445760.0 -8890.0 -0.09 -0.048 -0.4978 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I13 compound treatment 427520.0 -42500.0 -0.43 412090.0 -42600.0 -0.45 -0.621 -0.9999 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I14 compound treatment 384260.0 -85800.0 -0.87 456260.0 1610.0 0.02 -0.6047 -0.6933 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I15 compound treatment 535970.0 65900.0 0.67 462950.0 8300.0 0.09 0.535 0.7923 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I16 compound treatment 379220.0 -90800.0 -0.92 334090.0 -121000.0 -1.26 -1.546 -0.9881 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I17 compound treatment 518000.0 47900.0 0.49 511360.0 56700.0 0.59 0.7646 0.9951 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I18 compound treatment 465160.0 -4910.0 -0.05 431700.0 -22900.0 -0.24 -0.2053 -0.836 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I19 compound treatment 436580.0 -33500.0 -0.34 418400.0 -36200.0 -0.38 -0.5092 -0.9985 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I20 compound treatment 435150.0 -34900.0 -0.35 440520.0 -14100.0 -0.15 -0.3556 -0.9248 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I21 mock treatment 483930.0 13900.0 0.14 414120.0 -40500.0 -0.42 -0.2007 -0.4485 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I22 mock treatment 393570.0 -76500.0 -0.78 457130.0 2480.0 0.03 -0.5313 -0.6831 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I23 compound treatment 421800.0 -48300.0 -0.49 410140.0 -44500.0 -0.47 -0.6766 -0.9997 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 I24 compound treatment 435680.0 -34400.0 -0.35 365290.0 -89400.0 -0.94 -0.9091 -0.9097 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J01 compound treatment 423200.0 -46900.0 -0.48 418950.0 -35700.0 -0.37 -0.6013 -0.9928 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J02 compound treatment 528350.0 58300.0 0.59 340800.0 -114000.0 -1.19 -0.4247 -0.3189 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J03 compound treatment 389040.0 -81000.0 -0.82 413860.0 -40800.0 -0.43 -0.8844 -0.9533 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J04 compound treatment 423460.0 -46600.0 -0.47 351040.0 -104000.0 -1.09 -1.1025 -0.9309 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J05 mock treatment 409240.0 -60800.0 -0.62 456320.0 1670.0 0.02 -0.4247 -0.6868 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J06 mock treatment 432570.0 -37500.0 -0.38 386080.0 -68600.0 -0.72 -0.7775 -0.956 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J07 compound treatment 283870.0 -186000.0 -1.89 266040.0 -189000.0 -1.98 -2.7353 -0.9998 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J08 compound treatment 213640.0 -256000.0 -2.61 214210.0 -240000.0 -2.52 -3.624 -0.9999 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J09 compound treatment 386430.0 -83600.0 -0.85 314520.0 -140000.0 -1.47 -1.6392 -0.9662 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J10 compound treatment 471580.0 1510.0 0.02 432320.0 -22300.0 -0.23 -0.1546 -0.6593 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J11 compound treatment 521360.0 51300.0 0.52 394080.0 -60600.0 -0.63 -0.0802 -0.0976 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J12 compound treatment 422350.0 -47700.0 -0.48 338720.0 -116000.0 -1.21 -1.2018 -0.9189 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J13 compound treatment 232480.0 -238000.0 -2.41 51930.0 -403000.0 -4.22 -4.6909 -0.9649 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J14 compound treatment 412600.0 -57500.0 -0.58 377640.0 -77000.0 -0.81 -0.9835 -0.9874 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J15 compound treatment 491040.0 21000.0 0.21 470250.0 15600.0 0.16 0.2663 0.9914 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J16 compound treatment 242110.0 -228000.0 -2.32 276500.0 -178000.0 -1.87 -2.9579 -0.9943 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J17 compound treatment 247650.0 -222000.0 -2.26 162610.0 -292000.0 -3.06 -3.7619 -0.9889 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J18 compound treatment 456590.0 -13500.0 -0.14 463960.0 9310.0 0.1 -0.0279 -0.1657 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J19 compound treatment 514210.0 44100.0 0.45 485540.0 30900.0 0.32 0.5461 0.9872 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J20 compound treatment 422200.0 -47900.0 -0.49 433010.0 -21600.0 -0.23 -0.5043 -0.9396 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J21 mock treatment 467750.0 -2320.0 -0.02 463200.0 8550.0 0.09 0.0467 0.504 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J22 mock treatment 407220.0 -62800.0 -0.64 403040.0 -51600.0 -0.54 -0.834 -0.9966 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J23 compound treatment 418240.0 -51800.0 -0.53 389180.0 -65500.0 -0.69 -0.8575 -0.9915 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 J24 compound treatment 425840.0 -44200.0 -0.45 383700.0 -70900.0 -0.74 -0.8435 -0.971 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K01 compound treatment 281790.0 -188000.0 -1.91 277920.0 -177000.0 -1.85 -2.6622 -0.9999 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K02 compound treatment 422170.0 -47900.0 -0.49 520230.0 65600.0 0.69 0.1417 0.1683 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K03 compound treatment 369440.0 -101000.0 -1.02 418560.0 -36100.0 -0.38 -0.9905 -0.9085 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K04 compound treatment 363310.0 -107000.0 -1.08 386410.0 -68200.0 -0.71 -1.2727 -0.9795 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K05 compound treatment 486450.0 16400.0 0.17 464610.0 9960.0 0.1 0.1915 0.9747 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K06 compound treatment 314650.0 -155000.0 -1.58 305970.0 -149000.0 -1.56 -2.2183 -1.0 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K07 mock treatment 491470.0 21400.0 0.22 454880.0 232.0 0.0 0.1555 0.715 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K08 mock treatment 439310.0 -30800.0 -0.31 425760.0 -28900.0 -0.3 -0.4351 -0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K09 compound treatment 405610.0 -64500.0 -0.66 451360.0 -3290.0 -0.03 -0.4875 -0.7433 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K10 compound treatment 446120.0 -23900.0 -0.24 424170.0 -30500.0 -0.32 -0.3979 -0.991 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K11 compound treatment 526880.0 56800.0 0.58 504260.0 49600.0 0.52 0.7758 0.9986 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K12 compound treatment 249500.0 -221000.0 -2.24 203680.0 -251000.0 -2.63 -3.4443 -0.9968 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K13 compound treatment 439680.0 -30400.0 -0.31 546850.0 92200.0 0.97 0.4647 0.4582 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K14 compound treatment 495450.0 25400.0 0.26 473280.0 18600.0 0.2 0.3204 0.9906 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K15 mock treatment 549330.0 79300.0 0.81 410120.0 -44500.0 -0.47 0.2396 0.2575 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K16 mock treatment 533120.0 63100.0 0.64 517490.0 62800.0 0.66 0.9186 0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K17 compound treatment 299490.0 -171000.0 -1.73 256260.0 -198000.0 -2.08 -2.6955 -0.9959 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K18 compound treatment 273060.0 -197000.0 -2.0 9390.0 -445000.0 -4.67 -4.7144 -0.9287 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K19 compound treatment 570560.0 100000.0 1.02 407260.0 -47400.0 -0.5 0.371 0.3267 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K20 compound treatment 381770.0 -88300.0 -0.9 425220.0 -29400.0 -0.31 -0.8525 -0.8985 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K21 compound treatment 482610.0 12500.0 0.13 463550.0 8900.0 0.09 0.1561 0.9882 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K22 compound treatment 453380.0 -16700.0 -0.17 439930.0 -14700.0 -0.15 -0.229 -0.9989 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K23 mock treatment 472850.0 2780.0 0.03 488610.0 34000.0 0.36 0.2716 0.7609 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 K24 mock treatment 465890.0 -4180.0 -0.04 445920.0 -8730.0 -0.09 -0.0947 -0.9392 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L01 compound treatment 448410.0 -21700.0 -0.22 374430.0 -80200.0 -0.84 -0.75 -0.8632 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L02 compound treatment 262620.0 -207000.0 -2.11 260380.0 -194000.0 -2.04 -2.9299 -0.9998 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L03 compound treatment 424690.0 -45400.0 -0.46 433560.0 -21100.0 -0.22 -0.4823 -0.9432 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L04 compound treatment 494260.0 24200.0 0.25 443310.0 -11300.0 -0.12 0.0898 0.329 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L05 compound treatment 551530.0 81500.0 0.83 497970.0 43300.0 0.45 0.9063 0.96 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L06 compound treatment 346020.0 -124000.0 -1.26 447700.0 -6950.0 -0.07 -0.9429 -0.7467 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L07 mock treatment 380000.0 -90100.0 -0.92 438360.0 -16300.0 -0.17 -0.7679 -0.8247 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L08 mock treatment 547010.0 76900.0 0.78 475200.0 20600.0 0.22 0.7051 0.8695 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L09 compound treatment 239090.0 -231000.0 -2.35 116800.0 -338000.0 -3.54 -4.1628 -0.9801 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L10 compound treatment 566250.0 96200.0 0.98 407620.0 -47000.0 -0.49 0.3427 0.3131 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L11 compound treatment 444010.0 -26100.0 -0.26 447620.0 -7030.0 -0.07 -0.2393 -0.8707 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L12 compound treatment 304870.0 -165000.0 -1.68 269490.0 -185000.0 -1.94 -2.5589 -0.9974 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L13 compound treatment 289280.0 -181000.0 -1.84 228520.0 -226000.0 -2.37 -2.9744 -0.9921 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L14 compound treatment 523220.0 53200.0 0.54 420120.0 -34500.0 -0.36 0.1261 0.194 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L15 mock treatment 529220.0 59200.0 0.6 473780.0 19100.0 0.2 0.5668 0.8945 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L16 mock treatment 533120.0 63100.0 0.64 507080.0 52400.0 0.55 0.8415 0.9971 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L17 compound treatment 494920.0 24900.0 0.25 466050.0 11400.0 0.12 0.263 0.9416 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L18 compound treatment 284680.0 -185000.0 -1.88 259520.0 -195000.0 -2.04 -2.7778 -0.9992 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L19 compound treatment 415960.0 -54100.0 -0.55 405600.0 -49000.0 -0.51 -0.7522 -0.9994 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L20 compound treatment 470470.0 401.0 0.0 485920.0 31300.0 0.33 0.2346 0.7158 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L21 compound treatment 496890.0 26800.0 0.27 451320.0 -3330.0 -0.03 0.1681 0.6117 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L22 compound treatment 493120.0 23100.0 0.23 458670.0 4020.0 0.04 0.1954 0.8211 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L23 mock treatment 424340.0 -45700.0 -0.46 420200.0 -34400.0 -0.36 -0.5838 -0.9922 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 L24 mock treatment 489550.0 19500.0 0.2 469620.0 15000.0 0.16 0.2509 0.9934 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M01 compound treatment 426880.0 -43200.0 -0.44 392890.0 -61800.0 -0.65 -0.7679 -0.9821 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M02 compound treatment 464640.0 -5430.0 -0.06 476740.0 22100.0 0.23 0.1247 0.5239 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M03 compound treatment 452450.0 -17600.0 -0.18 443840.0 -10800.0 -0.11 -0.2067 -0.9756 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M04 compound treatment 461480.0 -8590.0 -0.09 408320.0 -46300.0 -0.49 -0.405 -0.8211 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M05 compound treatment 314330.0 -156000.0 -1.58 260660.0 -194000.0 -2.03 -2.5563 -0.9923 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M06 compound treatment 426960.0 -43100.0 -0.44 342780.0 -112000.0 -1.17 -1.1386 -0.9099 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M07 compound treatment 420270.0 -49800.0 -0.51 413280.0 -41400.0 -0.43 -0.6643 -0.997 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M08 compound treatment 441210.0 -28900.0 -0.29 387040.0 -67600.0 -0.71 -0.7083 -0.9238 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M09 mock treatment 520380.0 50300.0 0.51 556120.0 101000.0 1.06 1.1133 0.9437 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M10 mock treatment 529850.0 59800.0 0.61 503520.0 48900.0 0.51 0.7916 0.9964 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M11 compound treatment 343610.0 -126000.0 -1.29 371520.0 -83100.0 -0.87 -1.5246 -0.982 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M12 compound treatment 148600.0 -321000.0 -3.27 23850.0 -431000.0 -4.51 -5.5016 -0.9874 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M13 mock treatment 529050.0 59000.0 0.6 464160.0 9510.0 0.1 0.4943 0.8135 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M14 mock treatment 505390.0 35300.0 0.36 485680.0 31000.0 0.33 0.4837 0.9988 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M15 compound treatment 478370.0 8300.0 0.08 531750.0 77100.0 0.81 0.6309 0.7767 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M16 compound treatment 508430.0 38400.0 0.39 526000.0 71400.0 0.75 0.8043 0.9539 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M17 compound treatment 548370.0 78300.0 0.8 543960.0 89300.0 0.94 1.2243 0.9967 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M18 compound treatment 523120.0 53100.0 0.54 521170.0 66500.0 0.7 0.874 0.9919 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M19 compound treatment 440560.0 -29500.0 -0.3 471200.0 16600.0 0.17 -0.0894 -0.2581 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M20 compound treatment 469360.0 -709.0 -0.01 471970.0 17300.0 0.18 0.1232 0.6785 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M21 compound treatment 485760.0 15700.0 0.16 468930.0 14300.0 0.15 0.2186 0.9995 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M22 compound treatment 434800.0 -35300.0 -0.36 480450.0 25800.0 0.27 -0.0623 -0.1387 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M23 compound treatment 444980.0 -25100.0 -0.25 445810.0 -8840.0 -0.09 -0.2458 -0.906 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 M24 compound treatment 468520.0 -1550.0 -0.02 373490.0 -81200.0 -0.85 -0.6124 -0.7201 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N01 compound treatment 488960.0 18900.0 0.19 488250.0 33600.0 0.35 0.3847 0.9593 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N02 compound treatment 492920.0 22900.0 0.23 485870.0 31200.0 0.33 0.3955 0.9859 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N03 compound treatment 383850.0 -86200.0 -0.88 395920.0 -58700.0 -0.62 -1.0546 -0.985 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N04 compound treatment 363700.0 -106000.0 -1.08 348930.0 -106000.0 -1.11 -1.5476 -0.9999 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N05 compound treatment 383520.0 -86500.0 -0.88 393440.0 -61200.0 -0.64 -1.0754 -0.988 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N06 compound treatment 239440.0 -231000.0 -2.34 251250.0 -203000.0 -2.13 -3.1642 -0.9989 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N07 compound treatment 346200.0 -124000.0 -1.26 377280.0 -77400.0 -0.81 -1.4633 -0.9773 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N08 compound treatment 398930.0 -71100.0 -0.72 449330.0 -5320.0 -0.06 -0.5506 -0.7594 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N09 mock treatment 450470.0 -19600.0 -0.2 511140.0 56500.0 0.59 0.2777 0.4447 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N10 mock treatment 521310.0 51200.0 0.52 503170.0 48500.0 0.51 0.7277 0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N11 compound treatment 463560.0 -6510.0 -0.07 458080.0 3430.0 0.04 -0.0213 -0.2835 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N12 compound treatment 276280.0 -194000.0 -1.97 257320.0 -197000.0 -2.07 -2.8545 -0.9997 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N13 mock treatment 508060.0 38000.0 0.39 456750.0 2100.0 0.02 0.2886 0.7462 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N14 mock treatment 473220.0 3150.0 0.03 469380.0 14700.0 0.15 0.1318 0.836 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N15 compound treatment 310030.0 -160000.0 -1.63 176660.0 -278000.0 -2.91 -3.2095 -0.9621 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N16 compound treatment 391840.0 -78200.0 -0.79 357230.0 -97400.0 -1.02 -1.2839 -0.9924 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N17 compound treatment 486560.0 16500.0 0.17 481920.0 27300.0 0.29 0.3205 0.9677 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N18 compound treatment 353860.0 -116000.0 -1.18 306130.0 -149000.0 -1.56 -1.9354 -0.9907 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N19 compound treatment 490370.0 20300.0 0.21 493030.0 38400.0 0.4 0.4302 0.9519 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N20 compound treatment 290250.0 -180000.0 -1.83 290470.0 -164000.0 -1.72 -2.5085 -0.9995 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N21 compound treatment 389840.0 -80200.0 -0.82 401820.0 -52800.0 -0.55 -0.9679 -0.9822 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N22 compound treatment 377650.0 -92400.0 -0.94 362250.0 -92400.0 -0.97 -1.3486 -0.9999 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N23 compound treatment 410240.0 -59800.0 -0.61 456000.0 1350.0 0.01 -0.4199 -0.6904 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 N24 compound treatment 378560.0 -91500.0 -0.93 441330.0 -13300.0 -0.14 -0.7562 -0.8042 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O01 compound treatment 371840.0 -98200.0 -1.0 426970.0 -27700.0 -0.29 -0.9109 -0.8763 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O02 compound treatment 334300.0 -136000.0 -1.38 338160.0 -116000.0 -1.22 -1.8386 -0.9981 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O03 compound treatment 427890.0 -42200.0 -0.43 449800.0 -4850.0 -0.05 -0.339 -0.7854 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O04 compound treatment 471570.0 1500.0 0.02 429400.0 -25200.0 -0.26 -0.1763 -0.6652 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O05 compound treatment 497200.0 27100.0 0.28 447440.0 -7210.0 -0.08 0.1416 0.4952 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O06 compound treatment 392450.0 -77600.0 -0.79 413450.0 -41200.0 -0.43 -0.863 -0.9598 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O07 compound treatment 493460.0 23400.0 0.24 379330.0 -75300.0 -0.79 -0.3899 -0.4731 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O08 compound treatment 492350.0 22300.0 0.23 531520.0 76900.0 0.81 0.7296 0.8721 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O09 compound treatment 424580.0 -45500.0 -0.46 442280.0 -12400.0 -0.13 -0.4185 -0.8717 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O10 compound treatment 486810.0 16700.0 0.17 468490.0 13800.0 0.15 0.2228 0.9968 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O11 mock treatment 469600.0 -469.0 0.0 536210.0 81600.0 0.85 0.6009 0.7031 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O12 mock treatment 449920.0 -20100.0 -0.2 514660.0 60000.0 0.63 0.2998 0.4534 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O13 compound treatment 522240.0 52200.0 0.53 438310.0 -16300.0 -0.17 0.2538 0.4556 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O14 compound treatment 502930.0 32900.0 0.33 478150.0 23500.0 0.25 0.4102 0.9888 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O15 compound treatment 321280.0 -149000.0 -1.51 296200.0 -158000.0 -1.66 -2.2431 -0.9989 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O16 compound treatment 510770.0 40700.0 0.41 453120.0 -1530.0 -0.02 0.2811 0.6792 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O17 compound treatment 506520.0 36500.0 0.37 471520.0 16900.0 0.18 0.3869 0.9427 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O18 compound treatment 374000.0 -96100.0 -0.98 469290.0 14600.0 0.15 -0.5818 -0.5888 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O19 compound treatment 417180.0 -52900.0 -0.54 441020.0 -13600.0 -0.14 -0.481 -0.865 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O20 compound treatment 413930.0 -56100.0 -0.57 513020.0 58400.0 0.61 0.0291 0.0347 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O21 compound treatment 399850.0 -70200.0 -0.71 469700.0 15100.0 0.16 -0.3931 -0.5378 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O22 compound treatment 398150.0 -71900.0 -0.73 425840.0 -28800.0 -0.3 -0.7302 -0.9235 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O23 compound treatment 394740.0 -75300.0 -0.77 458890.0 4240.0 0.04 -0.5099 -0.6649 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 O24 compound treatment 418980.0 -51100.0 -0.52 508870.0 54200.0 0.57 0.0346 0.045 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P01 compound treatment 350580.0 -119000.0 -1.21 411520.0 -43100.0 -0.45 -1.1781 -0.9093 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P02 compound treatment 402470.0 -67600.0 -0.69 418160.0 -36500.0 -0.38 -0.7561 -0.9617 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P03 compound treatment 409980.0 -60100.0 -0.61 406600.0 -48000.0 -0.5 -0.7878 -0.9954 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P04 compound treatment 385140.0 -84900.0 -0.86 413450.0 -41200.0 -0.43 -0.9155 -0.9487 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P05 compound treatment 256340.0 -214000.0 -2.17 310580.0 -144000.0 -1.51 -2.6032 -0.9842 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P06 compound treatment 427090.0 -43000.0 -0.44 441120.0 -13500.0 -0.14 -0.4091 -0.8908 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P07 compound treatment 382400.0 -87700.0 -0.89 444650.0 -10000.0 -0.1 -0.704 -0.7848 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P08 compound treatment 355730.0 -114000.0 -1.16 340210.0 -114000.0 -1.2 -1.6694 -0.9999 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P09 compound treatment 367360.0 -103000.0 -1.04 434130.0 -20500.0 -0.21 -0.89 -0.8352 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P10 compound treatment 279310.0 -191000.0 -1.94 290190.0 -164000.0 -1.72 -2.5892 -0.9983 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P11 mock treatment 408650.0 -61400.0 -0.62 393490.0 -61200.0 -0.64 -0.8944 -0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P12 mock treatment 338080.0 -132000.0 -1.34 265700.0 -189000.0 -1.98 -2.3483 -0.982 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P13 compound treatment 402680.0 -67400.0 -0.68 415200.0 -39400.0 -0.41 -0.7765 -0.9708 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P14 compound treatment 242460.0 -228000.0 -2.31 234340.0 -220000.0 -2.31 -3.2677 -1.0 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P15 compound treatment 394090.0 -76000.0 -0.77 362080.0 -92600.0 -0.97 -1.2318 -0.9936 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P16 compound treatment 368360.0 -102000.0 -1.03 374330.0 -80300.0 -0.84 -1.3259 -0.9948 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P17 compound treatment 408320.0 -61700.0 -0.63 399870.0 -54800.0 -0.57 -0.8495 -0.999 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P18 compound treatment 387060.0 -83000.0 -0.84 357390.0 -97300.0 -1.02 -1.317 -0.9956 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P19 compound treatment 281090.0 -189000.0 -1.92 259010.0 -196000.0 -2.05 -2.8074 -0.9995 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P20 compound treatment 201330.0 -269000.0 -2.73 206920.0 -248000.0 -2.6 -3.7664 -0.9997 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P21 compound treatment 187270.0 -283000.0 -2.87 204450.0 -250000.0 -2.62 -3.8858 -0.9989 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P22 compound treatment 214950.0 -255000.0 -2.59 201820.0 -253000.0 -2.65 -3.7063 -0.9999 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P23 compound treatment 364170.0 -106000.0 -1.08 368860.0 -85800.0 -0.9 -1.3965 -0.996 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2095 P24 compound treatment 205550.0 -265000.0 -2.69 228730.0 -226000.0 -2.37 -3.5745 -0.998 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A01 compound treatment 512160.0 51000.0 0.52 413600.0 -32900.0 -0.35 0.1221 0.1963 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A02 compound treatment 433600.0 -27600.0 -0.28 429470.0 -17100.0 -0.18 -0.3248 -0.9763 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A03 compound treatment 278330.0 -183000.0 -1.86 239080.0 -207000.0 -2.17 -2.8511 -0.997 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A04 compound treatment 424350.0 -36900.0 -0.37 452020.0 5490.0 0.06 -0.2242 -0.5916 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A05 compound treatment 493180.0 32000.0 0.32 310750.0 -136000.0 -1.42 -0.7762 -0.5319 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A06 compound treatment 238030.0 -223000.0 -2.27 206270.0 -240000.0 -2.52 -3.3837 -0.9986 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A07 compound treatment 222840.0 -238000.0 -2.42 227770.0 -219000.0 -2.29 -3.3336 -0.9996 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A08 compound treatment 385620.0 -75600.0 -0.77 393340.0 -53200.0 -0.56 -0.9372 -0.9876 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A09 compound treatment 352870.0 -108000.0 -1.1 417480.0 -29100.0 -0.3 -0.9937 -0.87 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A10 compound treatment 479680.0 18500.0 0.19 406970.0 -39600.0 -0.41 -0.1604 -0.3524 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A11 compound treatment 400320.0 -60900.0 -0.62 343860.0 -103000.0 -1.08 -1.1982 -0.9655 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A12 compound treatment 439090.0 -22100.0 -0.22 374790.0 -71700.0 -0.75 -0.6904 -0.88 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A13 mock treatment 358400.0 -103000.0 -1.04 373120.0 -73400.0 -0.77 -1.2826 -0.9887 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A14 mock treatment 472610.0 11400.0 0.12 443330.0 -3200.0 -0.03 0.0582 0.4826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A15 compound treatment 385360.0 -75800.0 -0.77 412490.0 -34000.0 -0.36 -0.7972 -0.9387 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A16 compound treatment 263410.0 -198000.0 -2.01 232260.0 -214000.0 -2.25 -3.0088 -0.9985 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A17 compound treatment 404480.0 -56700.0 -0.58 372830.0 -73700.0 -0.77 -0.9537 -0.9896 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A18 compound treatment 246420.0 -215000.0 -2.18 209490.0 -237000.0 -2.48 -3.2996 -0.9979 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A19 compound treatment 419040.0 -42200.0 -0.43 318790.0 -128000.0 -1.34 -1.2494 -0.889 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A20 compound treatment 456480.0 -4730.0 -0.05 369220.0 -77300.0 -0.81 -0.6068 -0.7477 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A21 compound treatment 350000.0 -111000.0 -1.13 413890.0 -32600.0 -0.34 -1.0409 -0.8816 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A22 compound treatment 474610.0 13400.0 0.14 374000.0 -72500.0 -0.76 -0.4411 -0.5713 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A23 compound treatment 406750.0 -54500.0 -0.55 408340.0 -38200.0 -0.4 -0.6743 -0.9873 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 A24 compound treatment 421650.0 -39600.0 -0.4 395150.0 -51400.0 -0.54 -0.6649 -0.9896 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B01 compound treatment 406790.0 -54400.0 -0.55 414910.0 -31600.0 -0.33 -0.6253 -0.97 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B02 compound treatment 490880.0 29700.0 0.3 484550.0 38000.0 0.4 0.4949 0.9906 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B03 compound treatment 468590.0 7380.0 0.08 409830.0 -36700.0 -0.38 -0.2189 -0.5586 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B04 compound treatment 489200.0 28000.0 0.28 456110.0 9580.0 0.1 0.2721 0.9021 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B05 compound treatment 571550.0 110000.0 1.12 378800.0 -67700.0 -0.71 0.2911 0.2193 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B06 compound treatment 371160.0 -90000.0 -0.92 420530.0 -26000.0 -0.27 -0.8397 -0.8795 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B07 compound treatment 480200.0 19000.0 0.19 471690.0 25200.0 0.26 0.3229 0.9883 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B08 compound treatment 513340.0 52100.0 0.53 476900.0 30400.0 0.32 0.5996 0.9702 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B09 compound treatment 416260.0 -44900.0 -0.46 449000.0 2470.0 0.03 -0.3047 -0.666 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B10 compound treatment 480810.0 19600.0 0.2 494400.0 47900.0 0.5 0.4955 0.9182 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B11 compound treatment 439680.0 -21500.0 -0.22 323160.0 -123000.0 -1.29 -1.0687 -0.8152 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B12 compound treatment 408160.0 -53000.0 -0.54 314360.0 -132000.0 -1.38 -1.3604 -0.9154 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B13 mock treatment 518880.0 57700.0 0.59 480800.0 34300.0 0.36 0.6683 0.9723 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B14 mock treatment 511370.0 50200.0 0.51 447550.0 1020.0 0.01 0.368 0.7217 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B15 compound treatment 398100.0 -63100.0 -0.64 452360.0 5830.0 0.06 -0.4103 -0.6369 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B16 compound treatment 444070.0 -17100.0 -0.17 461170.0 14600.0 0.15 -0.0147 -0.0633 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B17 compound treatment 456490.0 -4720.0 -0.05 477940.0 31400.0 0.33 0.1988 0.5978 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B18 compound treatment 247930.0 -213000.0 -2.17 240030.0 -207000.0 -2.16 -3.0625 -1.0 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B19 compound treatment 428920.0 -32300.0 -0.33 439080.0 -7450.0 -0.08 -0.2872 -0.8516 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B20 compound treatment 238100.0 -223000.0 -2.27 266280.0 -180000.0 -1.89 -2.9386 -0.9959 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B21 compound treatment 364240.0 -97000.0 -0.99 429080.0 -17500.0 -0.18 -0.8261 -0.8242 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B22 compound treatment 414410.0 -46800.0 -0.48 400990.0 -45500.0 -0.48 -0.6737 -1.0 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B23 compound treatment 389280.0 -71900.0 -0.73 468160.0 21600.0 0.23 -0.3566 -0.466 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 B24 compound treatment 442510.0 -18700.0 -0.19 467250.0 20700.0 0.22 0.0191 0.0663 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C01 compound treatment 435650.0 -25600.0 -0.26 420220.0 -26300.0 -0.28 -0.3786 -0.9996 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C02 compound treatment 436550.0 -24700.0 -0.25 364000.0 -82500.0 -0.86 -0.7886 -0.876 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C03 compound treatment 335130.0 -126000.0 -1.28 315810.0 -131000.0 -1.37 -1.8744 -0.9994 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C04 compound treatment 216900.0 -244000.0 -2.48 191920.0 -255000.0 -2.67 -3.6419 -0.9994 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C05 compound treatment 221170.0 -240000.0 -2.44 203550.0 -243000.0 -2.55 -3.525 -0.9998 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C06 compound treatment 346690.0 -115000.0 -1.16 396590.0 -49900.0 -0.52 -1.1929 -0.9349 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C07 compound treatment 216670.0 -245000.0 -2.49 242030.0 -205000.0 -2.14 -3.2723 -0.9973 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C08 compound treatment 441940.0 -19300.0 -0.2 355040.0 -91500.0 -0.96 -0.8163 -0.8343 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C09 compound treatment 238240.0 -223000.0 -2.27 260170.0 -186000.0 -1.95 -2.9829 -0.9973 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C10 compound treatment 428760.0 -32400.0 -0.33 407850.0 -38700.0 -0.41 -0.5197 -0.9948 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C11 mock treatment 256750.0 -204000.0 -2.08 267700.0 -179000.0 -1.87 -2.7941 -0.9987 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C12 mock treatment 394690.0 -66500.0 -0.68 455010.0 8480.0 0.09 -0.4152 -0.609 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C13 compound treatment 376180.0 -85000.0 -0.86 373320.0 -73200.0 -0.77 -1.1534 -0.9982 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C14 compound treatment 438970.0 -22200.0 -0.23 404180.0 -42400.0 -0.44 -0.4736 -0.951 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C15 mock treatment 383720.0 -77500.0 -0.79 342730.0 -104000.0 -1.09 -1.3258 -0.9874 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C16 mock treatment 422040.0 -39200.0 -0.4 424670.0 -21900.0 -0.23 -0.4434 -0.9656 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C17 compound treatment 453330.0 -7880.0 -0.08 445180.0 -1350.0 -0.01 -0.0666 -0.8195 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C18 compound treatment 392320.0 -68900.0 -0.7 392290.0 -54200.0 -0.57 -0.8969 -0.9947 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C19 compound treatment 368650.0 -92600.0 -0.94 369150.0 -77400.0 -0.81 -1.2384 -0.9973 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C20 compound treatment 313540.0 -148000.0 -1.5 342250.0 -104000.0 -1.09 -1.8337 -0.9878 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C21 compound treatment 329030.0 -132000.0 -1.34 303930.0 -143000.0 -1.49 -2.0063 -0.9986 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C22 compound treatment 390720.0 -70500.0 -0.72 346980.0 -99600.0 -1.04 -1.2441 -0.9832 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C23 compound treatment 210670.0 -251000.0 -2.55 209520.0 -237000.0 -2.48 -3.5562 -0.9999 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 C24 compound treatment 399880.0 -61300.0 -0.62 397990.0 -48500.0 -0.51 -0.8003 -0.9949 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D01 compound treatment 466200.0 4990.0 0.05 497080.0 50500.0 0.53 0.4104 0.7713 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D02 compound treatment 319860.0 -141000.0 -1.44 378640.0 -67900.0 -0.71 -1.5187 -0.9475 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D03 compound treatment 365190.0 -96000.0 -0.98 380590.0 -65900.0 -0.69 -1.1785 -0.9857 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D04 compound treatment 367040.0 -94200.0 -0.96 373510.0 -73000.0 -0.77 -1.2177 -0.9939 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D05 compound treatment 367300.0 -93900.0 -0.95 387300.0 -59200.0 -0.62 -1.1136 -0.9783 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D06 compound treatment 430960.0 -30200.0 -0.31 456930.0 10400.0 0.11 -0.1403 -0.4303 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D07 compound treatment 446240.0 -15000.0 -0.15 369470.0 -77100.0 -0.81 -0.6785 -0.8258 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D08 compound treatment 336800.0 -124000.0 -1.26 261890.0 -185000.0 -1.93 -2.2619 -0.9787 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D09 compound treatment 289760.0 -171000.0 -1.74 272000.0 -175000.0 -1.83 -2.525 -0.9997 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D10 compound treatment 512480.0 51300.0 0.52 522620.0 76100.0 0.8 0.9321 0.9788 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D11 mock treatment 417840.0 -43400.0 -0.44 528640.0 82100.0 0.86 0.2967 0.3069 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D12 mock treatment 496220.0 35000.0 0.36 388740.0 -57800.0 -0.61 -0.1766 -0.2514 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D13 compound treatment 491860.0 30700.0 0.31 367380.0 -79200.0 -0.83 -0.3662 -0.4133 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D14 compound treatment 436200.0 -25000.0 -0.25 399240.0 -47300.0 -0.5 -0.5301 -0.9519 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D15 mock treatment 430840.0 -30400.0 -0.31 431840.0 -14700.0 -0.15 -0.3271 -0.9484 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D16 mock treatment 466350.0 5140.0 0.05 493780.0 47200.0 0.5 0.387 0.7774 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D17 compound treatment 409450.0 -51800.0 -0.53 484650.0 38100.0 0.4 -0.0895 -0.1355 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D18 compound treatment 412480.0 -48700.0 -0.5 437960.0 -8570.0 -0.09 -0.4136 -0.8219 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D19 compound treatment 380320.0 -80900.0 -0.82 374130.0 -72400.0 -0.76 -1.1176 -0.9992 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D20 compound treatment 455700.0 -5510.0 -0.06 338200.0 -108000.0 -1.14 -0.8422 -0.7411 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D21 compound treatment 405760.0 -55400.0 -0.56 390270.0 -56300.0 -0.59 -0.8153 -0.9997 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D22 compound treatment 436590.0 -24600.0 -0.25 459060.0 12500.0 0.13 -0.0841 -0.2976 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D23 compound treatment 426740.0 -34500.0 -0.35 398560.0 -48000.0 -0.5 -0.6031 -0.9844 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 D24 compound treatment 375410.0 -85800.0 -0.87 327260.0 -119000.0 -1.25 -1.5002 -0.9845 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E01 mock treatment 345120.0 -116000.0 -1.18 443110.0 -3420.0 -0.04 -0.8595 -0.7283 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E02 mock treatment 421950.0 -39300.0 -0.4 513510.0 67000.0 0.7 0.2141 0.2653 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E03 compound treatment 238560.0 -223000.0 -2.26 225850.0 -221000.0 -2.31 -3.2349 -0.9999 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E04 compound treatment 287930.0 -173000.0 -1.76 259420.0 -187000.0 -1.96 -2.6314 -0.9986 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E05 compound treatment 381760.0 -79400.0 -0.81 339360.0 -107000.0 -1.12 -1.3649 -0.9869 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E06 compound treatment 427470.0 -33700.0 -0.34 497520.0 51000.0 0.53 0.1353 0.2132 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E07 compound treatment 404400.0 -56800.0 -0.58 390210.0 -56300.0 -0.59 -0.8255 -0.9999 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E08 compound treatment 425080.0 -36100.0 -0.37 480210.0 33700.0 0.35 -0.0101 -0.0198 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E09 mock treatment 414250.0 -47000.0 -0.48 449690.0 3160.0 0.03 -0.314 -0.6565 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E10 mock treatment 414910.0 -46300.0 -0.47 421980.0 -24600.0 -0.26 -0.5146 -0.9597 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E11 compound treatment 258330.0 -203000.0 -2.06 261600.0 -185000.0 -1.94 -2.8279 -0.9995 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E12 compound treatment 373600.0 -87600.0 -0.89 462940.0 16400.0 0.17 -0.508 -0.5602 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E13 compound treatment 239950.0 -221000.0 -2.25 215700.0 -231000.0 -2.42 -3.3001 -0.9993 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E14 compound treatment 395520.0 -65700.0 -0.67 444440.0 -2090.0 -0.02 -0.4875 -0.7299 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E15 compound treatment 448320.0 -12900.0 -0.13 384340.0 -62200.0 -0.65 -0.5534 -0.8326 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E16 compound treatment 370880.0 -90300.0 -0.92 424030.0 -22500.0 -0.24 -0.8158 -0.8608 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E17 mock treatment 439530.0 -21700.0 -0.22 404290.0 -42200.0 -0.44 -0.4687 -0.9481 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E18 mock treatment 409090.0 -52100.0 -0.53 435160.0 -11400.0 -0.12 -0.4588 -0.8451 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E19 compound treatment 240750.0 -220000.0 -2.24 265310.0 -181000.0 -1.9 -2.9268 -0.9966 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E20 compound treatment 396400.0 -64800.0 -0.66 423120.0 -23400.0 -0.25 -0.6391 -0.9094 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E21 compound treatment 223040.0 -238000.0 -2.42 217610.0 -229000.0 -2.4 -3.4074 -1.0 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E22 compound treatment 249780.0 -211000.0 -2.15 204990.0 -242000.0 -2.53 -3.3088 -0.9967 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E23 compound treatment 230630.0 -231000.0 -2.34 261120.0 -185000.0 -1.94 -3.0305 -0.9957 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 E24 compound treatment 202680.0 -259000.0 -2.63 195680.0 -251000.0 -2.63 -3.7162 -1.0 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F01 mock treatment 405880.0 -55300.0 -0.56 510020.0 63500.0 0.67 0.0728 0.0836 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F02 mock treatment 376030.0 -85200.0 -0.87 506790.0 60300.0 0.63 -0.1656 -0.1546 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F03 compound treatment 325570.0 -136000.0 -1.38 470160.0 23600.0 0.25 -0.7996 -0.571 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F04 compound treatment 453140.0 -8070.0 -0.08 412450.0 -34100.0 -0.36 -0.3105 -0.8474 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F05 compound treatment 401350.0 -59900.0 -0.61 353760.0 -92800.0 -0.97 -1.1174 -0.9745 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F06 compound treatment 348640.0 -113000.0 -1.14 312370.0 -134000.0 -1.41 -1.8028 -0.9948 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F07 compound treatment 460030.0 -1180.0 -0.01 379900.0 -66600.0 -0.7 -0.5021 -0.7191 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F08 compound treatment 474640.0 13400.0 0.14 421690.0 -24800.0 -0.26 -0.0875 -0.2978 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F09 mock treatment 509460.0 48300.0 0.49 478470.0 31900.0 0.33 0.5833 0.9826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F10 mock treatment 512890.0 51700.0 0.53 505780.0 59200.0 0.62 0.8103 0.9965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F11 compound treatment 420010.0 -41200.0 -0.42 488350.0 41800.0 0.44 0.0138 0.0227 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F12 compound treatment 372320.0 -88900.0 -0.9 396100.0 -50400.0 -0.53 -1.0124 -0.9674 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F13 compound treatment 450720.0 -10500.0 -0.11 473920.0 27400.0 0.29 0.1275 0.4167 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F14 compound treatment 388110.0 -73100.0 -0.74 441690.0 -4840.0 -0.05 -0.5611 -0.7536 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F15 compound treatment 268040.0 -193000.0 -1.96 236590.0 -210000.0 -2.2 -2.9434 -0.9984 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F16 compound treatment 375010.0 -86200.0 -0.88 291610.0 -155000.0 -1.62 -1.7672 -0.9581 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F17 mock treatment 485980.0 24800.0 0.25 401640.0 -44900.0 -0.47 -0.1546 -0.2898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F18 mock treatment 472000.0 10800.0 0.11 503070.0 56500.0 0.59 0.4964 0.824 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F19 compound treatment 256370.0 -205000.0 -2.08 236880.0 -210000.0 -2.2 -3.0252 -0.9996 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F20 compound treatment 413520.0 -47700.0 -0.48 406610.0 -39900.0 -0.42 -0.6384 -0.9973 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F21 compound treatment 318210.0 -143000.0 -1.45 304550.0 -142000.0 -1.49 -2.0794 -0.9999 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F22 compound treatment 405500.0 -55700.0 -0.57 366330.0 -80200.0 -0.84 -0.9945 -0.9815 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F23 compound treatment 362660.0 -98500.0 -1.0 424370.0 -22200.0 -0.23 -0.8723 -0.8486 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 F24 compound treatment 389660.0 -71500.0 -0.73 431750.0 -14800.0 -0.15 -0.6236 -0.8389 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G01 compound treatment 478470.0 17300.0 0.18 468880.0 22300.0 0.23 0.2896 0.9899 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G02 compound treatment 499520.0 38300.0 0.39 455070.0 8540.0 0.09 0.3386 0.8475 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G03 mock treatment 478370.0 17200.0 0.17 462780.0 16200.0 0.17 0.2437 0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G04 mock treatment 555410.0 94200.0 0.96 354740.0 -91800.0 -0.96 -0.0032 -0.0023 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G05 compound treatment 238300.0 -223000.0 -2.27 238920.0 -208000.0 -2.18 -3.1399 -0.9998 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G06 compound treatment 265000.0 -196000.0 -1.99 217290.0 -229000.0 -2.4 -3.1083 -0.9957 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G07 compound treatment 251400.0 -210000.0 -2.13 268550.0 -178000.0 -1.86 -2.8262 -0.9978 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G08 compound treatment 219640.0 -242000.0 -2.45 276350.0 -170000.0 -1.78 -2.9967 -0.9877 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G09 compound treatment 427250.0 -34000.0 -0.35 440290.0 -6240.0 -0.07 -0.2903 -0.8264 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G10 compound treatment 460320.0 -888.0 -0.01 421920.0 -24600.0 -0.26 -0.1887 -0.7314 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G11 compound treatment 236240.0 -225000.0 -2.29 270600.0 -176000.0 -1.84 -2.92 -0.9943 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G12 compound treatment 430760.0 -30400.0 -0.31 386570.0 -60000.0 -0.63 -0.663 -0.9468 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G13 compound treatment 382580.0 -78600.0 -0.8 427120.0 -19400.0 -0.2 -0.7088 -0.8597 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G14 compound treatment 363730.0 -97500.0 -0.99 404560.0 -42000.0 -0.44 -1.0114 -0.9332 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G15 compound treatment 473380.0 12200.0 0.12 516280.0 69700.0 0.73 0.6042 0.8152 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G16 compound treatment 260010.0 -201000.0 -2.04 258890.0 -188000.0 -1.97 -2.8359 -0.9998 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G17 compound treatment 406880.0 -54300.0 -0.55 472510.0 26000.0 0.27 -0.1979 -0.3215 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G18 compound treatment 239310.0 -222000.0 -2.25 228640.0 -218000.0 -2.28 -3.2088 -1.0 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G19 mock treatment 443520.0 -17700.0 -0.18 473600.0 27100.0 0.28 0.0734 0.2187 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G20 mock treatment 500550.0 39300.0 0.4 452640.0 6110.0 0.06 0.328 0.81 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G21 compound treatment 263070.0 -198000.0 -2.01 224960.0 -222000.0 -2.32 -3.0653 -0.9975 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G22 compound treatment 467200.0 5990.0 0.06 405050.0 -41500.0 -0.43 -0.2643 -0.6022 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G23 compound treatment 387520.0 -73700.0 -0.75 464640.0 18100.0 0.19 -0.3953 -0.5118 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 G24 compound treatment 384850.0 -76400.0 -0.78 401120.0 -45400.0 -0.48 -0.8851 -0.9724 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H01 compound treatment 458510.0 -2700.0 -0.03 442720.0 -3810.0 -0.04 -0.0476 -0.9831 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H02 compound treatment 362600.0 -98600.0 -1.0 379070.0 -67500.0 -0.71 -1.2084 -0.9854 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H03 mock treatment 423240.0 -38000.0 -0.39 464640.0 18100.0 0.19 -0.1387 -0.3225 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H04 mock treatment 523270.0 62100.0 0.63 375630.0 -70900.0 -0.74 -0.0793 -0.0814 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H05 compound treatment 427220.0 -34000.0 -0.35 330140.0 -116000.0 -1.22 -1.1065 -0.873 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H06 compound treatment 352920.0 -108000.0 -1.1 413280.0 -33300.0 -0.35 -1.0245 -0.8876 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H07 compound treatment 480050.0 18800.0 0.19 378500.0 -68000.0 -0.71 -0.3686 -0.4995 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H08 compound treatment 407440.0 -53800.0 -0.55 368000.0 -78500.0 -0.82 -0.9682 -0.9802 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H09 compound treatment 391010.0 -70200.0 -0.71 310080.0 -136000.0 -1.43 -1.5154 -0.9484 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H10 compound treatment 384730.0 -76500.0 -0.78 368280.0 -78300.0 -0.82 -1.1293 -0.9996 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H11 compound treatment 361440.0 -99800.0 -1.01 346130.0 -100000.0 -1.05 -1.4608 -0.9998 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H12 compound treatment 469830.0 8620.0 0.09 495890.0 49400.0 0.52 0.4276 0.8153 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H13 compound treatment 372320.0 -88900.0 -0.9 378660.0 -67900.0 -0.71 -1.1416 -0.993 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H14 compound treatment 393440.0 -67800.0 -0.69 368960.0 -77600.0 -0.81 -1.0617 -0.9966 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H15 compound treatment 488670.0 27500.0 0.28 434310.0 -12200.0 -0.13 0.1068 0.3478 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H16 compound treatment 385790.0 -75400.0 -0.77 375880.0 -70700.0 -0.74 -1.0654 -0.9998 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H17 compound treatment 455610.0 -5600.0 -0.06 474600.0 28100.0 0.29 0.1677 0.56 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H18 compound treatment 481290.0 20100.0 0.2 420910.0 -25600.0 -0.27 -0.0455 -0.135 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H19 mock treatment 417060.0 -44100.0 -0.45 444450.0 -2080.0 -0.02 -0.3327 -0.7406 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H20 mock treatment 442880.0 -18300.0 -0.19 437130.0 -9400.0 -0.1 -0.2014 -0.9557 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H21 compound treatment 242850.0 -218000.0 -2.22 183450.0 -263000.0 -2.76 -3.5182 -0.9942 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H22 compound treatment 352390.0 -109000.0 -1.11 400680.0 -45900.0 -0.48 -1.1216 -0.9303 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H23 compound treatment 353670.0 -108000.0 -1.09 353990.0 -92500.0 -0.97 -1.4584 -0.9982 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 H24 compound treatment 428640.0 -32600.0 -0.33 404200.0 -42300.0 -0.44 -0.5476 -0.9896 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I01 compound treatment 256850.0 -204000.0 -2.08 251150.0 -195000.0 -2.05 -2.916 -1.0 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I02 compound treatment 440720.0 -20500.0 -0.21 305320.0 -141000.0 -1.48 -1.1934 -0.7987 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I03 compound treatment 364060.0 -97100.0 -0.99 387640.0 -58900.0 -0.62 -1.1344 -0.9744 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I04 compound treatment 257660.0 -204000.0 -2.07 267630.0 -179000.0 -1.87 -2.7881 -0.9988 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I05 mock treatment 304480.0 -157000.0 -1.59 421920.0 -24600.0 -0.26 -1.3085 -0.811 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I06 mock treatment 505070.0 43900.0 0.45 418580.0 -28000.0 -0.29 0.1081 0.2027 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I07 compound treatment 432850.0 -28400.0 -0.29 466250.0 19700.0 0.21 -0.0577 -0.1627 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I08 compound treatment 401760.0 -59400.0 -0.6 522590.0 76100.0 0.8 0.1363 0.1363 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I09 compound treatment 424590.0 -36600.0 -0.37 392110.0 -54400.0 -0.57 -0.6663 -0.9786 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I10 compound treatment 264190.0 -197000.0 -2.0 262520.0 -184000.0 -1.93 -2.779 -0.9998 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I11 compound treatment 428860.0 -32300.0 -0.33 417070.0 -29500.0 -0.31 -0.4507 -0.9995 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I12 compound treatment 414610.0 -46600.0 -0.47 429130.0 -17400.0 -0.18 -0.4638 -0.914 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I13 compound treatment 419590.0 -41600.0 -0.42 477790.0 31300.0 0.33 -0.0675 -0.1261 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I14 compound treatment 260650.0 -201000.0 -2.04 268650.0 -178000.0 -1.86 -2.759 -0.999 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I15 compound treatment 531210.0 70000.0 0.71 445010.0 -1520.0 -0.02 0.4917 0.6911 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I16 compound treatment 462470.0 1260.0 0.01 486100.0 39600.0 0.41 0.3022 0.7286 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I17 compound treatment 459130.0 -2080.0 -0.02 451970.0 5440.0 0.06 0.0254 0.4174 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I18 compound treatment 460750.0 -458.0 0.0 455750.0 9220.0 0.1 0.065 0.6723 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I19 compound treatment 296240.0 -165000.0 -1.68 290720.0 -156000.0 -1.63 -2.3398 -0.9999 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I20 compound treatment 259370.0 -202000.0 -2.05 252080.0 -194000.0 -2.04 -2.891 -1.0 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I21 mock treatment 405120.0 -56100.0 -0.57 395320.0 -51200.0 -0.54 -0.7824 -0.9995 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I22 mock treatment 429520.0 -31700.0 -0.32 451560.0 5030.0 0.05 -0.1904 -0.5837 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I23 compound treatment 399920.0 -61300.0 -0.62 432580.0 -14000.0 -0.15 -0.5438 -0.85 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 I24 compound treatment 476260.0 15100.0 0.15 425820.0 -20700.0 -0.22 -0.0453 -0.1706 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J01 compound treatment 21930.0 -439000.0 -4.46 15600.0 -431000.0 -4.52 -6.3492 -1.0 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J02 compound treatment 426110.0 -35100.0 -0.36 318080.0 -128000.0 -1.35 -1.2039 -0.8646 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J03 compound treatment 476520.0 15300.0 0.16 505760.0 59200.0 0.62 0.5488 0.8579 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J04 compound treatment 456450.0 -4760.0 -0.05 333700.0 -113000.0 -1.18 -0.8701 -0.7354 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J05 mock treatment 544160.0 83000.0 0.84 369030.0 -77500.0 -0.81 0.0219 0.0187 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J06 mock treatment 365770.0 -95400.0 -0.97 396160.0 -50400.0 -0.53 -1.059 -0.9591 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J07 compound treatment 428640.0 -32600.0 -0.33 345540.0 -101000.0 -1.06 -0.9822 -0.8859 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J08 compound treatment 360270.0 -101000.0 -1.03 327010.0 -120000.0 -1.25 -1.6108 -0.9951 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J09 compound treatment 532360.0 71200.0 0.72 414400.0 -32100.0 -0.34 0.2732 0.3426 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J10 compound treatment 446960.0 -14200.0 -0.14 414980.0 -31600.0 -0.33 -0.3361 -0.9314 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J11 compound treatment 451590.0 -9620.0 -0.1 475370.0 28800.0 0.3 0.1445 0.4552 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J12 compound treatment 469160.0 7950.0 0.08 429200.0 -17300.0 -0.18 -0.0713 -0.3585 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J13 compound treatment 463590.0 2380.0 0.02 453490.0 6960.0 0.07 0.0687 0.8939 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J14 compound treatment 415400.0 -45800.0 -0.47 446950.0 418.0 0.0 -0.3261 -0.7004 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J15 compound treatment 457240.0 -3970.0 -0.04 490240.0 43700.0 0.46 0.2953 0.6424 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J16 compound treatment 411390.0 -49800.0 -0.51 414480.0 -32100.0 -0.34 -0.5954 -0.9801 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J17 compound treatment 502990.0 41800.0 0.42 460930.0 14400.0 0.15 0.4069 0.903 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J18 compound treatment 456530.0 -4680.0 -0.05 439690.0 -6840.0 -0.07 -0.0843 -0.9801 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J19 compound treatment 471010.0 9800.0 0.1 438240.0 -8290.0 -0.09 0.009 0.0681 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J20 compound treatment 323440.0 -138000.0 -1.4 344730.0 -102000.0 -1.07 -1.7442 -0.991 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J21 mock treatment 443410.0 -17800.0 -0.18 434400.0 -12100.0 -0.13 -0.2178 -0.9851 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J22 mock treatment 421720.0 -39500.0 -0.4 432320.0 -14200.0 -0.15 -0.389 -0.9089 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J23 compound treatment 398250.0 -63000.0 -0.64 469040.0 22500.0 0.24 -0.2856 -0.4189 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 J24 compound treatment 344410.0 -117000.0 -1.19 305920.0 -141000.0 -1.47 -1.881 -0.9943 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K01 compound treatment 496800.0 35600.0 0.36 441440.0 -5090.0 -0.05 0.218 0.5964 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K02 compound treatment 510880.0 49700.0 0.5 409850.0 -36700.0 -0.38 0.0852 0.1342 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K03 compound treatment 393130.0 -68100.0 -0.69 544000.0 97500.0 1.02 0.2329 0.1888 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K04 compound treatment 460700.0 -508.0 -0.01 462450.0 15900.0 0.17 0.1143 0.6849 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K05 compound treatment 362760.0 -98400.0 -1.0 367760.0 -78800.0 -0.83 -1.291 -0.9954 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K06 compound treatment 363800.0 -97400.0 -0.99 370930.0 -75600.0 -0.79 -1.2601 -0.9939 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K07 mock treatment 585760.0 125000.0 1.27 537350.0 90800.0 0.95 1.5678 0.9901 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K08 mock treatment 503110.0 41900.0 0.43 439000.0 -7530.0 -0.08 0.2453 0.5664 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K09 compound treatment 437080.0 -24100.0 -0.25 429820.0 -16700.0 -0.18 -0.2972 -0.9864 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K10 compound treatment 522160.0 61000.0 0.62 440610.0 -5920.0 -0.06 0.3941 0.6331 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K11 compound treatment 576170.0 115000.0 1.17 445120.0 -1410.0 -0.01 0.8156 0.6981 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K12 compound treatment 422040.0 -39200.0 -0.4 489510.0 43000.0 0.45 0.037 0.0615 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K13 compound treatment 496320.0 35100.0 0.36 482930.0 36400.0 0.38 0.522 0.9994 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K14 compound treatment 471430.0 10200.0 0.1 404110.0 -42400.0 -0.44 -0.2408 -0.5276 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K15 mock treatment 411630.0 -49600.0 -0.5 478190.0 31700.0 0.33 -0.1217 -0.2018 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K16 mock treatment 538680.0 77500.0 0.79 488700.0 42200.0 0.44 0.8691 0.9627 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K17 compound treatment 435040.0 -26200.0 -0.27 429010.0 -17500.0 -0.18 -0.3178 -0.9836 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K18 compound treatment 590120.0 129000.0 1.31 441070.0 -5460.0 -0.06 0.8859 0.6756 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K19 compound treatment 277920.0 -183000.0 -1.86 254480.0 -192000.0 -2.01 -2.7399 -0.9993 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K20 compound treatment 474350.0 13100.0 0.13 436530.0 -10000.0 -0.1 0.0203 0.1198 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K21 compound treatment 441190.0 -20000.0 -0.2 429450.0 -17100.0 -0.18 -0.2704 -0.998 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K22 compound treatment 540880.0 79700.0 0.81 438020.0 -8510.0 -0.09 0.5094 0.6254 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K23 mock treatment 491780.0 30600.0 0.31 484640.0 38100.0 0.4 0.502 0.9923 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 K24 mock treatment 465370.0 4160.0 0.04 409600.0 -36900.0 -0.39 -0.2437 -0.6261 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L01 compound treatment 392480.0 -68700.0 -0.7 325930.0 -121000.0 -1.26 -1.3874 -0.9609 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L02 compound treatment 333190.0 -128000.0 -1.3 349300.0 -97200.0 -1.02 -1.6403 -0.9927 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L03 compound treatment 393800.0 -67400.0 -0.69 396530.0 -50000.0 -0.52 -0.8548 -0.9912 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L04 compound treatment 392560.0 -68600.0 -0.7 385960.0 -60600.0 -0.63 -0.942 -0.9989 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L05 compound treatment 388920.0 -72300.0 -0.73 415270.0 -31300.0 -0.33 -0.751 -0.9338 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L06 compound treatment 426520.0 -34700.0 -0.35 439760.0 -6770.0 -0.07 -0.2994 -0.8327 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L07 mock treatment 501120.0 39900.0 0.41 465760.0 19200.0 0.2 0.4293 0.9478 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L08 mock treatment 450500.0 -10700.0 -0.11 436740.0 -9790.0 -0.1 -0.1495 -0.9996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L09 compound treatment 450010.0 -11200.0 -0.11 449230.0 2700.0 0.03 -0.0605 -0.5158 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L10 compound treatment 399040.0 -62200.0 -0.63 417970.0 -28600.0 -0.3 -0.6583 -0.9417 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L11 compound treatment 464040.0 2830.0 0.03 430160.0 -16400.0 -0.17 -0.1009 -0.5803 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L12 compound treatment 378320.0 -82900.0 -0.84 443970.0 -2560.0 -0.03 -0.6146 -0.7293 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L13 compound treatment 456170.0 -5040.0 -0.05 408230.0 -38300.0 -0.4 -0.32 -0.7909 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L14 compound treatment 407280.0 -53900.0 -0.55 332960.0 -114000.0 -1.19 -1.2289 -0.9381 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L15 mock treatment 521710.0 60500.0 0.61 474370.0 27800.0 0.29 0.641 0.9419 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L16 mock treatment 511690.0 50500.0 0.51 490080.0 43500.0 0.46 0.6854 0.9983 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L17 compound treatment 138490.0 -323000.0 -3.28 126240.0 -320000.0 -3.36 -4.6919 -0.9999 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L18 compound treatment 475870.0 14700.0 0.15 490260.0 43700.0 0.46 0.4293 0.8911 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L19 compound treatment 307070.0 -154000.0 -1.57 282420.0 -164000.0 -1.72 -2.3234 -0.9989 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L20 compound treatment 412700.0 -48500.0 -0.49 462240.0 15700.0 0.16 -0.2322 -0.4468 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L21 compound treatment 383320.0 -77900.0 -0.79 334740.0 -112000.0 -1.17 -1.3879 -0.9818 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L22 compound treatment 461700.0 492.0 0.01 447630.0 1100.0 0.01 0.0117 0.9305 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L23 mock treatment 490310.0 29100.0 0.3 417240.0 -29300.0 -0.31 -0.0079 -0.0185 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 L24 mock treatment 456640.0 -4570.0 -0.05 445460.0 -1070.0 -0.01 -0.0408 -0.8536 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M01 compound treatment 425690.0 -35500.0 -0.36 507640.0 61100.0 0.64 0.1975 0.2687 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M02 compound treatment 344530.0 -117000.0 -1.19 449530.0 3000.0 0.03 -0.8162 -0.6881 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M03 compound treatment 492870.0 31700.0 0.32 388260.0 -58300.0 -0.61 -0.2042 -0.2959 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M04 compound treatment 261220.0 -200000.0 -2.03 216650.0 -230000.0 -2.41 -3.1402 -0.9964 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M05 compound treatment 248280.0 -213000.0 -2.16 222340.0 -224000.0 -2.35 -3.191 -0.9992 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M06 compound treatment 428540.0 -32700.0 -0.33 399530.0 -47000.0 -0.49 -0.583 -0.9816 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M07 compound treatment 281340.0 -180000.0 -1.83 220430.0 -226000.0 -2.37 -2.9676 -0.9918 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M08 compound treatment 246730.0 -214000.0 -2.18 258670.0 -188000.0 -1.97 -2.933 -0.9987 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M09 mock treatment 353700.0 -108000.0 -1.09 365300.0 -81200.0 -0.85 -1.3743 -0.9924 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M10 mock treatment 521320.0 60100.0 0.61 508080.0 61500.0 0.64 0.8879 0.9996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M11 compound treatment 437450.0 -23800.0 -0.24 420340.0 -26200.0 -0.27 -0.3648 -0.998 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M12 compound treatment 517600.0 56400.0 0.57 458290.0 11800.0 0.12 0.4923 0.8399 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M13 mock treatment 494670.0 33500.0 0.34 471140.0 24600.0 0.26 0.4228 0.9907 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M14 mock treatment 505640.0 44400.0 0.45 451150.0 4620.0 0.05 0.3535 0.7784 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M15 compound treatment 516050.0 54800.0 0.56 479270.0 32700.0 0.34 0.6366 0.9728 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M16 compound treatment 459140.0 -2070.0 -0.02 440640.0 -5890.0 -0.06 -0.0585 -0.8972 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M17 compound treatment 457920.0 -3290.0 -0.03 461890.0 15400.0 0.16 0.0902 0.5486 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M18 compound treatment 444800.0 -16400.0 -0.17 432730.0 -13800.0 -0.14 -0.2202 -0.9975 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M19 compound treatment 256000.0 -205000.0 -2.09 261000.0 -186000.0 -1.94 -2.8491 -0.9994 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M20 compound treatment 440320.0 -20900.0 -0.21 435160.0 -11400.0 -0.12 -0.2343 -0.9627 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M21 compound treatment 334400.0 -127000.0 -1.29 313290.0 -133000.0 -1.4 -1.8984 -0.9992 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M22 compound treatment 230400.0 -231000.0 -2.35 238170.0 -208000.0 -2.18 -3.2022 -0.9994 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M23 compound treatment 240440.0 -221000.0 -2.24 250890.0 -196000.0 -2.05 -3.0358 -0.999 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 M24 compound treatment 217600.0 -244000.0 -2.48 239380.0 -207000.0 -2.17 -3.2852 -0.9979 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N01 compound treatment 422760.0 -38400.0 -0.39 452180.0 5650.0 0.06 -0.2344 -0.5932 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N02 compound treatment 387810.0 -73400.0 -0.75 356860.0 -89700.0 -0.94 -1.1918 -0.9935 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N03 compound treatment 466720.0 5510.0 0.06 411930.0 -34600.0 -0.36 -0.2167 -0.5908 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N04 compound treatment 340010.0 -121000.0 -1.23 390800.0 -55700.0 -0.58 -1.2838 -0.9419 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N05 compound treatment 451380.0 -9830.0 -0.1 487080.0 40500.0 0.42 0.2298 0.5265 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N06 compound treatment 462560.0 1350.0 0.01 423700.0 -22800.0 -0.24 -0.1594 -0.6654 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N07 compound treatment 386340.0 -74900.0 -0.76 428610.0 -17900.0 -0.19 -0.6708 -0.8559 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N08 compound treatment 455560.0 -5650.0 -0.06 404580.0 -42000.0 -0.44 -0.3514 -0.7927 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N09 mock treatment 533230.0 72000.0 0.73 505550.0 59000.0 0.62 0.9548 0.9965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N10 mock treatment 426260.0 -34900.0 -0.36 429280.0 -17300.0 -0.18 -0.3789 -0.9509 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N11 compound treatment 521140.0 59900.0 0.61 486560.0 40000.0 0.42 0.7272 0.9834 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N12 compound treatment 479560.0 18400.0 0.19 466830.0 20300.0 0.21 0.2823 0.9979 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N13 mock treatment 494180.0 33000.0 0.34 413780.0 -32800.0 -0.34 -0.0057 -0.0119 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N14 mock treatment 514270.0 53100.0 0.54 505500.0 59000.0 0.62 0.8182 0.9977 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N15 compound treatment 459000.0 -2210.0 -0.02 361570.0 -85000.0 -0.89 -0.6453 -0.7247 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N16 compound treatment 474300.0 13100.0 0.13 418620.0 -27900.0 -0.29 -0.1127 -0.3508 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N17 compound treatment 435270.0 -25900.0 -0.26 423490.0 -23000.0 -0.24 -0.3571 -0.999 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N18 compound treatment 443320.0 -17900.0 -0.18 372370.0 -74200.0 -0.78 -0.678 -0.8496 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N19 compound treatment 432800.0 -28400.0 -0.29 420050.0 -26500.0 -0.28 -0.4003 -0.9998 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N20 compound treatment 256600.0 -205000.0 -2.08 256210.0 -190000.0 -1.99 -2.8803 -0.9998 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N21 compound treatment 299790.0 -161000.0 -1.64 317400.0 -129000.0 -1.35 -2.1166 -0.9954 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N22 compound treatment 435010.0 -26200.0 -0.27 422330.0 -24200.0 -0.25 -0.3676 -0.9997 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N23 compound treatment 430260.0 -30900.0 -0.31 395560.0 -51000.0 -0.53 -0.6 -0.9681 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 N24 compound treatment 457340.0 -3870.0 -0.04 470660.0 24100.0 0.25 0.151 0.5901 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O01 compound treatment 434300.0 -26900.0 -0.27 442370.0 -4160.0 -0.04 -0.2242 -0.8096 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O02 compound treatment 487970.0 26800.0 0.27 449980.0 3450.0 0.04 0.2179 0.7941 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O03 compound treatment 226240.0 -235000.0 -2.39 231490.0 -215000.0 -2.25 -3.2816 -0.9996 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O04 compound treatment 479070.0 17900.0 0.18 482990.0 36500.0 0.38 0.3985 0.9422 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O05 compound treatment 259280.0 -202000.0 -2.05 251410.0 -195000.0 -2.04 -2.8966 -1.0 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O06 compound treatment 435290.0 -25900.0 -0.26 423110.0 -23400.0 -0.25 -0.3598 -0.9994 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O07 compound treatment 277310.0 -184000.0 -1.87 262980.0 -184000.0 -1.92 -2.6813 -0.9999 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O08 compound treatment 257700.0 -204000.0 -2.07 258320.0 -188000.0 -1.97 -2.8568 -0.9997 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O09 compound treatment 469440.0 8230.0 0.08 435300.0 -11200.0 -0.12 -0.0241 -0.1666 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O10 compound treatment 398190.0 -63000.0 -0.64 429120.0 -17400.0 -0.18 -0.5818 -0.8738 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O11 mock treatment 545570.0 84400.0 0.86 539650.0 93100.0 0.98 1.2961 0.9979 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O12 mock treatment 499300.0 38100.0 0.39 436530.0 -10000.0 -0.1 0.1996 0.4978 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O13 compound treatment 480000.0 18800.0 0.19 502130.0 55600.0 0.58 0.5469 0.8922 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O14 compound treatment 460360.0 -848.0 -0.01 444850.0 -1680.0 -0.02 -0.0186 -0.9458 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O15 compound treatment 411490.0 -49700.0 -0.51 426020.0 -20500.0 -0.21 -0.5092 -0.9275 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O16 compound treatment 467560.0 6350.0 0.06 475590.0 29100.0 0.3 0.2609 0.8384 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O17 compound treatment 216540.0 -245000.0 -2.49 225280.0 -221000.0 -2.32 -3.3973 -0.9994 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O18 compound treatment 262210.0 -199000.0 -2.02 287910.0 -159000.0 -1.66 -2.6051 -0.9953 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O19 compound treatment 233950.0 -227000.0 -2.31 257550.0 -189000.0 -1.98 -3.0331 -0.9971 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O20 compound treatment 407520.0 -53700.0 -0.55 476270.0 29700.0 0.31 -0.1655 -0.2634 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O21 compound treatment 343530.0 -118000.0 -1.2 355700.0 -90800.0 -0.95 -1.5185 -0.9936 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O22 compound treatment 438240.0 -23000.0 -0.23 426630.0 -19900.0 -0.21 -0.3125 -0.9984 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O23 compound treatment 363650.0 -97600.0 -0.99 388200.0 -58300.0 -0.61 -1.1332 -0.973 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 O24 compound treatment 472370.0 11200.0 0.11 432880.0 -13700.0 -0.14 -0.0209 -0.1147 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P01 compound treatment 348710.0 -112000.0 -1.14 368400.0 -78100.0 -0.82 -1.3872 -0.9866 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P02 compound treatment 385660.0 -75500.0 -0.77 391200.0 -55300.0 -0.58 -0.9528 -0.9904 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P03 compound treatment 408180.0 -53000.0 -0.54 421290.0 -25200.0 -0.26 -0.5681 -0.9463 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P04 compound treatment 282260.0 -179000.0 -1.82 470730.0 24200.0 0.25 -1.1066 -0.6027 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P05 compound treatment 413690.0 -47500.0 -0.48 420350.0 -26200.0 -0.27 -0.5354 -0.9641 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P06 compound treatment 328000.0 -133000.0 -1.35 375610.0 -70900.0 -0.74 -1.4826 -0.9601 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P07 compound treatment 370010.0 -91200.0 -0.93 403080.0 -43500.0 -0.46 -0.9772 -0.9464 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P08 compound treatment 397010.0 -64200.0 -0.65 405440.0 -41100.0 -0.43 -0.7657 -0.9797 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P09 compound treatment 400480.0 -60700.0 -0.62 345990.0 -101000.0 -1.05 -1.1813 -0.9675 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P10 compound treatment 378560.0 -82600.0 -0.84 391970.0 -54600.0 -0.57 -0.9981 -0.9824 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P11 mock treatment 417210.0 -44000.0 -0.45 404420.0 -42100.0 -0.44 -0.6281 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P12 mock treatment 382100.0 -79100.0 -0.8 365390.0 -81100.0 -0.85 -1.1696 -0.9996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P13 compound treatment 172700.0 -289000.0 -2.93 171360.0 -275000.0 -2.88 -4.1118 -1.0 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P14 compound treatment 377990.0 -83200.0 -0.85 375550.0 -71000.0 -0.74 -1.1239 -0.9979 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P15 compound treatment 285880.0 -175000.0 -1.78 291540.0 -155000.0 -1.62 -2.4081 -0.9989 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P16 compound treatment 340770.0 -120000.0 -1.22 354990.0 -91500.0 -0.96 -1.5436 -0.9927 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P17 compound treatment 6520.0 -455000.0 -4.62 15630.0 -431000.0 -4.51 -6.4597 -0.9999 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P18 compound treatment 243680.0 -218000.0 -2.21 254450.0 -192000.0 -2.01 -2.9862 -0.9989 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P19 compound treatment 12690.0 -449000.0 -4.56 16530.0 -430000.0 -4.51 -6.4087 -1.0 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P20 compound treatment 402560.0 -58600.0 -0.6 390850.0 -55700.0 -0.58 -0.834 -0.9999 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P21 compound treatment 405280.0 -55900.0 -0.57 429700.0 -16800.0 -0.18 -0.5266 -0.8849 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P22 compound treatment 343410.0 -118000.0 -1.2 349840.0 -96700.0 -1.01 -1.5628 -0.9966 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P23 compound treatment 249320.0 -212000.0 -2.15 238080.0 -208000.0 -2.18 -3.0669 -1.0 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2096 P24 compound treatment 360570.0 -101000.0 -1.02 374240.0 -72300.0 -0.76 -1.2587 -0.9891 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A01 compound treatment 465350.0 11600.0 0.12 443710.0 29500.0 0.31 0.3025 0.913 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A02 compound treatment 336830.0 -117000.0 -1.19 386490.0 -27700.0 -0.29 -1.0449 -0.8547 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A03 compound treatment 359530.0 -94200.0 -0.96 288740.0 -125000.0 -1.31 -1.606 -0.9879 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A04 compound treatment 356670.0 -97000.0 -0.99 387280.0 -26900.0 -0.28 -0.8965 -0.8742 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A05 compound treatment 409650.0 -44100.0 -0.45 411290.0 -2880.0 -0.03 -0.3379 -0.7531 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A06 compound treatment 156100.0 -298000.0 -3.02 166450.0 -248000.0 -2.6 -3.9738 -0.9971 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A07 compound treatment 296740.0 -157000.0 -1.6 324450.0 -89700.0 -0.94 -1.7926 -0.9682 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A08 compound treatment 416650.0 -37100.0 -0.38 365450.0 -48700.0 -0.51 -0.6272 -0.9888 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A09 compound treatment 392400.0 -61300.0 -0.62 298850.0 -115000.0 -1.21 -1.2949 -0.9525 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A10 compound treatment 326080.0 -128000.0 -1.3 357930.0 -56200.0 -0.59 -1.3338 -0.9363 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A11 compound treatment 353970.0 -99700.0 -1.01 332660.0 -81500.0 -0.85 -1.3206 -0.9964 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A12 compound treatment 307650.0 -146000.0 -1.48 363380.0 -50800.0 -0.53 -1.4258 -0.9043 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A13 mock treatment 345890.0 -108000.0 -1.1 374740.0 -39400.0 -0.41 -1.0669 -0.9111 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A14 mock treatment 409090.0 -44600.0 -0.45 325930.0 -88200.0 -0.92 -0.9744 -0.9462 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A15 compound treatment 396960.0 -56700.0 -0.58 390370.0 -23800.0 -0.25 -0.5841 -0.9297 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A16 compound treatment 354320.0 -99400.0 -1.01 418160.0 3990.0 0.04 -0.6846 -0.6773 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A17 compound treatment 356160.0 -97500.0 -0.99 347200.0 -67000.0 -0.7 -1.1971 -0.9857 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A18 compound treatment 336270.0 -117000.0 -1.19 378080.0 -36100.0 -0.38 -1.1113 -0.8877 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A19 compound treatment 438610.0 -15100.0 -0.15 400720.0 -13500.0 -0.14 -0.2081 -0.9991 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A20 compound treatment 405120.0 -48600.0 -0.49 386830.0 -27300.0 -0.29 -0.5517 -0.9665 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A21 compound treatment 374940.0 -78800.0 -0.8 366910.0 -47300.0 -0.5 -0.9161 -0.9733 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A22 compound treatment 450120.0 -3590.0 -0.04 374570.0 -39600.0 -0.41 -0.3192 -0.7663 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A23 compound treatment 482570.0 28900.0 0.29 390240.0 -23900.0 -0.25 0.0301 0.078 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 A24 compound treatment 439840.0 -13900.0 -0.14 396280.0 -17900.0 -0.19 -0.2322 -0.9901 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B01 compound treatment 446030.0 -7680.0 -0.08 437030.0 22900.0 0.24 0.1142 0.4533 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B02 compound treatment 502880.0 49200.0 0.5 422280.0 8110.0 0.08 0.4134 0.8156 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B03 compound treatment 340450.0 -113000.0 -1.15 394570.0 -19600.0 -0.21 -0.959 -0.8203 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B04 compound treatment 427260.0 -26400.0 -0.27 443770.0 29600.0 0.31 0.0292 0.0713 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B05 compound treatment 345440.0 -108000.0 -1.1 446130.0 32000.0 0.33 -0.5412 -0.4706 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B06 compound treatment 411960.0 -41700.0 -0.42 384580.0 -29600.0 -0.31 -0.5192 -0.9881 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B07 compound treatment 253870.0 -200000.0 -2.03 288730.0 -125000.0 -1.31 -2.3653 -0.9778 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B08 compound treatment 372160.0 -81500.0 -0.83 368380.0 -45800.0 -0.48 -0.9252 -0.9662 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B09 compound treatment 413460.0 -40200.0 -0.41 390560.0 -23600.0 -0.25 -0.4641 -0.971 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B10 compound treatment 373080.0 -80600.0 -0.82 376960.0 -37200.0 -0.39 -0.855 -0.9423 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B11 compound treatment 486430.0 32700.0 0.33 416290.0 2120.0 0.02 0.2508 0.7526 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B12 compound treatment 456980.0 3270.0 0.03 464420.0 50200.0 0.53 0.3958 0.7503 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B13 mock treatment 379240.0 -74500.0 -0.76 430750.0 16600.0 0.17 -0.4123 -0.531 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B14 mock treatment 448640.0 -5070.0 -0.05 440420.0 26200.0 0.28 0.1581 0.5649 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B15 compound treatment 454980.0 1270.0 0.01 380360.0 -33800.0 -0.35 -0.2414 -0.6808 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B16 compound treatment 352720.0 -101000.0 -1.03 434880.0 20700.0 0.22 -0.5722 -0.5455 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B17 compound treatment 371600.0 -82100.0 -0.83 390880.0 -23300.0 -0.24 -0.7626 -0.8772 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B18 compound treatment 390900.0 -62800.0 -0.64 285820.0 -128000.0 -1.34 -1.4022 -0.942 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B19 compound treatment 432040.0 -21700.0 -0.22 395520.0 -18700.0 -0.2 -0.2939 -0.9982 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B20 compound treatment 437980.0 -15700.0 -0.16 382160.0 -32000.0 -0.34 -0.3502 -0.9425 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B21 compound treatment 487620.0 33900.0 0.34 419040.0 4870.0 0.05 0.2798 0.803 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B22 compound treatment 459950.0 6240.0 0.06 454520.0 40300.0 0.42 0.3438 0.8042 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B23 compound treatment 466200.0 12500.0 0.13 454080.0 39900.0 0.42 0.3854 0.882 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 B24 compound treatment 455070.0 1360.0 0.01 460440.0 46300.0 0.48 0.3526 0.727 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C01 compound treatment 383220.0 -70500.0 -0.72 393480.0 -20700.0 -0.22 -0.6598 -0.8816 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C02 compound treatment 398880.0 -54800.0 -0.56 336280.0 -77900.0 -0.82 -0.971 -0.9827 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C03 compound treatment 303620.0 -150000.0 -1.53 310360.0 -104000.0 -1.09 -1.8476 -0.9863 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C04 compound treatment 416610.0 -37100.0 -0.38 334200.0 -80000.0 -0.84 -0.8591 -0.935 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C05 compound treatment 346610.0 -107000.0 -1.09 341380.0 -72800.0 -0.76 -1.3089 -0.9849 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C06 compound treatment 402200.0 -51500.0 -0.52 306360.0 -108000.0 -1.13 -1.1689 -0.9389 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C07 compound treatment 338950.0 -115000.0 -1.17 318480.0 -95700.0 -1.0 -1.5336 -0.9972 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C08 compound treatment 435310.0 -18400.0 -0.19 364370.0 -49800.0 -0.52 -0.5012 -0.9042 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C09 compound treatment 355880.0 -97800.0 -0.99 284560.0 -130000.0 -1.36 -1.6632 -0.9882 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C10 compound treatment 435590.0 -18100.0 -0.18 358160.0 -56000.0 -0.59 -0.5452 -0.8863 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C11 mock treatment 440800.0 -12900.0 -0.13 433040.0 18900.0 0.2 0.047 0.1983 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C12 mock treatment 366090.0 -87600.0 -0.89 414560.0 389.0 0.0 -0.6267 -0.7039 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C13 compound treatment 368190.0 -85500.0 -0.87 354400.0 -59800.0 -0.63 -1.0573 -0.9871 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C14 compound treatment 289980.0 -164000.0 -1.66 270490.0 -144000.0 -1.51 -2.241 -0.9988 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C15 mock treatment 402600.0 -51100.0 -0.52 364690.0 -49500.0 -0.52 -0.7338 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C16 mock treatment 378210.0 -75500.0 -0.77 381780.0 -32400.0 -0.34 -0.7825 -0.9327 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C17 compound treatment 440180.0 -13500.0 -0.14 381530.0 -32600.0 -0.34 -0.339 -0.9198 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C18 compound treatment 376270.0 -77400.0 -0.79 367800.0 -46400.0 -0.49 -0.9 -0.9731 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C19 compound treatment 481480.0 27800.0 0.28 454520.0 40300.0 0.42 0.4985 0.9807 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C20 compound treatment 52480.0 -401000.0 -4.08 105700.0 -308000.0 -3.23 -5.1685 -0.9934 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C21 compound treatment 363300.0 -90400.0 -0.92 372480.0 -41700.0 -0.44 -0.9585 -0.9422 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C22 compound treatment 389460.0 -64200.0 -0.65 355450.0 -58700.0 -0.62 -0.8967 -0.9996 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C23 compound treatment 332610.0 -121000.0 -1.23 311490.0 -103000.0 -1.08 -1.6309 -0.9978 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 C24 compound treatment 416000.0 -37700.0 -0.38 342200.0 -72000.0 -0.75 -0.8042 -0.9507 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D01 compound treatment 472800.0 19100.0 0.19 368080.0 -46100.0 -0.48 -0.2043 -0.3925 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D02 compound treatment 445870.0 -7840.0 -0.08 371400.0 -42800.0 -0.45 -0.3732 -0.8199 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D03 compound treatment 411750.0 -42000.0 -0.43 408960.0 -5210.0 -0.05 -0.3401 -0.7912 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D04 compound treatment 361280.0 -92400.0 -0.94 324710.0 -89500.0 -0.94 -1.3269 -1.0 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D05 compound treatment 339960.0 -114000.0 -1.16 402410.0 -11800.0 -0.12 -0.9045 -0.7781 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D06 compound treatment 327930.0 -126000.0 -1.28 289970.0 -124000.0 -1.3 -1.824 -1.0 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D07 compound treatment 490960.0 37300.0 0.38 406470.0 -7700.0 -0.08 0.2106 0.5442 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D08 compound treatment 396730.0 -57000.0 -0.58 349400.0 -64800.0 -0.68 -0.8893 -0.9969 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D09 compound treatment 372970.0 -80700.0 -0.82 387850.0 -26300.0 -0.28 -0.7752 -0.8955 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D10 compound treatment 383360.0 -70300.0 -0.71 288320.0 -126000.0 -1.32 -1.4379 -0.9586 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D11 mock treatment 458190.0 4480.0 0.05 394290.0 -19900.0 -0.21 -0.1151 -0.5397 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D12 mock treatment 371620.0 -82100.0 -0.83 438040.0 23900.0 0.25 -0.413 -0.4743 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D13 compound treatment 442240.0 -11500.0 -0.12 439060.0 24900.0 0.26 0.102 0.3571 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D14 compound treatment 472850.0 19100.0 0.19 413560.0 -611.0 -0.01 0.133 0.6835 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D15 mock treatment 472500.0 18800.0 0.19 368910.0 -45300.0 -0.47 -0.2003 -0.3918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D16 mock treatment 456680.0 2970.0 0.03 401310.0 -12900.0 -0.13 -0.0739 -0.5353 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D17 compound treatment 439950.0 -13800.0 -0.14 367520.0 -46700.0 -0.49 -0.4445 -0.8743 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D18 compound treatment 321440.0 -132000.0 -1.34 330770.0 -83400.0 -0.87 -1.5683 -0.9783 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D19 compound treatment 421410.0 -32300.0 -0.33 351620.0 -62600.0 -0.66 -0.6955 -0.9489 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D20 compound treatment 414900.0 -38800.0 -0.39 387200.0 -27000.0 -0.28 -0.4787 -0.9866 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D21 compound treatment 352820.0 -101000.0 -1.03 330320.0 -83900.0 -0.88 -1.3462 -0.997 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D22 compound treatment 396860.0 -56800.0 -0.58 345500.0 -68700.0 -0.72 -0.9173 -0.9941 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D23 compound treatment 394000.0 -59700.0 -0.61 388560.0 -25600.0 -0.27 -0.6188 -0.9327 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 D24 compound treatment 395580.0 -58100.0 -0.59 454150.0 40000.0 0.42 -0.1215 -0.1678 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E01 mock treatment 459650.0 5940.0 0.06 409070.0 -5100.0 -0.05 0.0049 0.0609 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E02 mock treatment 493450.0 39700.0 0.4 455550.0 41400.0 0.43 0.5921 0.9994 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E03 compound treatment 438590.0 -15100.0 -0.15 346500.0 -67700.0 -0.71 -0.61 -0.8408 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E04 compound treatment 419710.0 -34000.0 -0.35 365120.0 -49100.0 -0.51 -0.6077 -0.9813 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E05 compound treatment 391200.0 -62500.0 -0.64 377090.0 -37100.0 -0.39 -0.7239 -0.9722 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E06 compound treatment 335530.0 -118000.0 -1.2 255690.0 -158000.0 -1.66 -2.0233 -0.9873 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E07 compound treatment 478010.0 24300.0 0.25 469280.0 55100.0 0.58 0.5829 0.9282 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E08 compound treatment 476330.0 22600.0 0.23 459040.0 44900.0 0.47 0.495 0.9459 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E09 mock treatment 425240.0 -28500.0 -0.29 394400.0 -19800.0 -0.21 -0.351 -0.9866 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E10 mock treatment 446750.0 -6960.0 -0.07 411880.0 -2290.0 -0.02 -0.067 -0.8969 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E11 compound treatment 447310.0 -6400.0 -0.07 359260.0 -54900.0 -0.58 -0.4528 -0.782 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E12 compound treatment 209670.0 -244000.0 -2.48 171200.0 -243000.0 -2.55 -3.5537 -0.9999 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E13 compound treatment 420960.0 -32700.0 -0.33 405710.0 -8460.0 -0.09 -0.298 -0.8653 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E14 compound treatment 114510.0 -339000.0 -3.45 72970.0 -341000.0 -3.57 -4.9652 -0.9998 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E15 compound treatment 415140.0 -38600.0 -0.39 372660.0 -41500.0 -0.43 -0.5847 -0.9987 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E16 compound treatment 471290.0 17600.0 0.18 393370.0 -20800.0 -0.22 -0.0278 -0.0985 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E17 mock treatment 404480.0 -49200.0 -0.5 421930.0 7760.0 0.08 -0.2962 -0.5845 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E18 mock treatment 451790.0 -1920.0 -0.02 394370.0 -19800.0 -0.21 -0.1605 -0.7701 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E19 compound treatment 329510.0 -124000.0 -1.26 324330.0 -89800.0 -0.94 -1.5581 -0.9896 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E20 compound treatment 364600.0 -89100.0 -0.91 321300.0 -92900.0 -0.97 -1.3284 -0.9994 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E21 compound treatment 284970.0 -169000.0 -1.71 249490.0 -165000.0 -1.73 -2.4326 -1.0 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E22 compound treatment 430180.0 -23500.0 -0.24 313640.0 -101000.0 -1.05 -0.9139 -0.8461 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E23 compound treatment 424400.0 -29300.0 -0.3 398840.0 -15300.0 -0.16 -0.3242 -0.958 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 E24 compound treatment 296020.0 -158000.0 -1.6 330150.0 -84000.0 -0.88 -1.7556 -0.9602 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F01 mock treatment 507360.0 53700.0 0.55 493630.0 79500.0 0.83 0.9742 0.9789 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F02 mock treatment 441840.0 -11900.0 -0.12 404540.0 -9630.0 -0.1 -0.1566 -0.9961 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F03 compound treatment 357720.0 -96000.0 -0.98 329060.0 -85100.0 -0.89 -1.3203 -0.999 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F04 compound treatment 416960.0 -36700.0 -0.37 393690.0 -20500.0 -0.21 -0.4158 -0.9654 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F05 compound treatment 306820.0 -147000.0 -1.49 246130.0 -168000.0 -1.76 -2.3005 -0.9966 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F06 compound treatment 386080.0 -67600.0 -0.69 333670.0 -80500.0 -0.84 -1.0824 -0.9948 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F07 compound treatment 475140.0 21400.0 0.22 359950.0 -54200.0 -0.57 -0.2477 -0.4071 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F08 compound treatment 488930.0 35200.0 0.36 438140.0 24000.0 0.25 0.4307 0.985 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F09 mock treatment 393400.0 -60300.0 -0.61 337920.0 -76300.0 -0.8 -0.9983 -0.9914 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F10 mock treatment 533930.0 80200.0 0.82 441840.0 27700.0 0.29 0.7814 0.9032 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F11 compound treatment 375220.0 -78500.0 -0.8 315320.0 -98900.0 -1.04 -1.2963 -0.9917 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F12 compound treatment 292030.0 -162000.0 -1.64 221020.0 -193000.0 -2.02 -2.5928 -0.9947 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F13 compound treatment 455360.0 1650.0 0.02 304570.0 -110000.0 -1.15 -0.8001 -0.6967 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F14 compound treatment 536960.0 83300.0 0.85 385120.0 -29100.0 -0.3 0.383 0.426 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F15 compound treatment 399440.0 -54300.0 -0.55 322240.0 -91900.0 -0.96 -1.071 -0.965 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F16 compound treatment 447460.0 -6250.0 -0.06 422950.0 8780.0 0.09 0.0202 0.1803 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F17 mock treatment 405180.0 -48500.0 -0.49 414560.0 389.0 0.0 -0.3458 -0.7012 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F18 mock treatment 466800.0 13100.0 0.13 462240.0 48100.0 0.5 0.4502 0.8643 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F19 compound treatment 413080.0 -40600.0 -0.41 367850.0 -46300.0 -0.49 -0.6351 -0.9968 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F20 compound treatment 393020.0 -60700.0 -0.62 398280.0 -15900.0 -0.17 -0.5538 -0.867 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F21 compound treatment 407360.0 -46300.0 -0.47 373060.0 -41100.0 -0.43 -0.6376 -0.999 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F22 compound treatment 450310.0 -3400.0 -0.03 384800.0 -29400.0 -0.31 -0.242 -0.7815 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F23 compound treatment 387960.0 -65700.0 -0.67 376480.0 -37700.0 -0.39 -0.7517 -0.9685 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 F24 compound treatment 394560.0 -59100.0 -0.6 334280.0 -79900.0 -0.84 -1.0169 -0.9868 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G01 compound treatment 443240.0 -10500.0 -0.11 387220.0 -27000.0 -0.28 -0.2749 -0.911 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G02 compound treatment 361770.0 -91900.0 -0.93 335290.0 -78900.0 -0.83 -1.245 -0.9981 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G03 mock treatment 391540.0 -62200.0 -0.63 506780.0 92600.0 0.97 0.2394 0.2068 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G04 mock treatment 416000.0 -37700.0 -0.38 448740.0 34600.0 0.36 -0.0148 -0.0281 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G05 compound treatment 437300.0 -16400.0 -0.17 412080.0 -2090.0 -0.02 -0.1334 -0.7932 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G06 compound treatment 531330.0 77600.0 0.79 397770.0 -16400.0 -0.17 0.4363 0.5404 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G07 compound treatment 442240.0 -11500.0 -0.12 302080.0 -112000.0 -1.17 -0.9129 -0.7735 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G08 compound treatment 437720.0 -16000.0 -0.16 341920.0 -72300.0 -0.76 -0.6502 -0.8397 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G09 compound treatment 554910.0 101000.0 1.03 374680.0 -39500.0 -0.41 0.4346 0.3921 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G10 compound treatment 495450.0 41700.0 0.42 473050.0 58900.0 0.62 0.7362 0.9833 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G11 compound treatment 375850.0 -77900.0 -0.79 389330.0 -24800.0 -0.26 -0.7435 -0.8927 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G12 compound treatment 365090.0 -88600.0 -0.9 320980.0 -93200.0 -0.98 -1.3272 -0.9992 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G13 compound treatment 391360.0 -62300.0 -0.63 420640.0 6470.0 0.07 -0.4001 -0.6279 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G14 compound treatment 353790.0 -99900.0 -1.02 280260.0 -134000.0 -1.4 -1.7101 -0.9874 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G15 compound treatment 440320.0 -13400.0 -0.14 384800.0 -29400.0 -0.31 -0.3138 -0.9326 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G16 compound treatment 444380.0 -9330.0 -0.09 372510.0 -41700.0 -0.44 -0.3757 -0.8411 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G17 compound treatment 510940.0 57200.0 0.58 425670.0 11500.0 0.12 0.4964 0.8358 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G18 compound treatment 474160.0 20500.0 0.21 391040.0 -23100.0 -0.24 -0.0244 -0.0764 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G19 mock treatment 474030.0 20300.0 0.21 433120.0 18900.0 0.2 0.2864 0.9998 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G20 mock treatment 478420.0 24700.0 0.25 380250.0 -33900.0 -0.36 -0.0737 -0.1694 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G21 compound treatment 435290.0 -18400.0 -0.19 358030.0 -56100.0 -0.59 -0.5483 -0.8882 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G22 compound treatment 503560.0 49900.0 0.51 366400.0 -47800.0 -0.5 0.0043 0.006 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G23 compound treatment 366720.0 -87000.0 -0.88 392670.0 -21500.0 -0.23 -0.7844 -0.8598 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 G24 compound treatment 267040.0 -187000.0 -1.9 294790.0 -119000.0 -1.25 -2.2258 -0.9796 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H01 compound treatment 455680.0 1970.0 0.02 411390.0 -2780.0 -0.03 -0.0064 -0.1818 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H02 compound treatment 494190.0 40500.0 0.41 474040.0 59900.0 0.63 0.7344 0.9791 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H03 mock treatment 483720.0 30000.0 0.3 385190.0 -29000.0 -0.3 0.001 0.0022 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H04 mock treatment 302920.0 -151000.0 -1.53 385440.0 -28700.0 -0.3 -1.2964 -0.8302 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H05 compound treatment 404870.0 -48800.0 -0.5 406250.0 -7920.0 -0.08 -0.4096 -0.814 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H06 compound treatment 446720.0 -6990.0 -0.07 371960.0 -42200.0 -0.44 -0.3629 -0.8103 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H07 compound treatment 442080.0 -11600.0 -0.12 468320.0 54100.0 0.57 0.3176 0.5481 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H08 compound treatment 487100.0 33400.0 0.34 376850.0 -37300.0 -0.39 -0.0366 -0.0706 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H09 compound treatment 334720.0 -119000.0 -1.21 300750.0 -113000.0 -1.19 -1.6953 -1.0 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H10 compound treatment 427100.0 -26600.0 -0.27 441620.0 27400.0 0.29 0.0122 0.0308 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H11 compound treatment 351210.0 -102000.0 -1.04 339750.0 -74400.0 -0.78 -1.2879 -0.9898 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H12 compound treatment 348320.0 -105000.0 -1.07 383640.0 -30500.0 -0.32 -0.9835 -0.8799 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H13 compound treatment 309600.0 -144000.0 -1.46 322100.0 -92100.0 -0.96 -1.7176 -0.9795 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H14 compound treatment 437800.0 -15900.0 -0.16 392410.0 -21800.0 -0.23 -0.2755 -0.9858 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H15 compound treatment 422960.0 -30700.0 -0.31 352130.0 -62000.0 -0.65 -0.6806 -0.9436 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H16 compound treatment 452910.0 -797.0 -0.01 390120.0 -24100.0 -0.25 -0.1839 -0.7295 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H17 compound treatment 491200.0 37500.0 0.38 412750.0 -1420.0 -0.01 0.2589 0.679 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H18 compound treatment 434190.0 -19500.0 -0.2 456820.0 42600.0 0.45 0.1757 0.3594 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H19 mock treatment 418270.0 -35400.0 -0.36 394240.0 -19900.0 -0.21 -0.4023 -0.9664 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H20 mock treatment 504710.0 51000.0 0.52 403410.0 -10800.0 -0.11 0.2868 0.5406 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H21 compound treatment 415560.0 -38100.0 -0.39 403040.0 -11100.0 -0.12 -0.3566 -0.8808 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H22 compound treatment 424250.0 -29500.0 -0.3 429040.0 14900.0 0.16 -0.1015 -0.3008 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H23 compound treatment 456960.0 3250.0 0.03 369280.0 -44900.0 -0.47 -0.3092 -0.6558 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 H24 compound treatment 402080.0 -51600.0 -0.52 338720.0 -75500.0 -0.79 -0.93 -0.9802 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I01 compound treatment 367360.0 -86300.0 -0.88 357010.0 -57200.0 -0.6 -1.044 -0.9827 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I02 compound treatment 477250.0 23500.0 0.24 443330.0 29200.0 0.31 0.3852 0.9927 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I03 compound treatment 404110.0 -49600.0 -0.5 445920.0 31700.0 0.33 -0.1212 -0.2006 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I04 compound treatment 388480.0 -65200.0 -0.66 391200.0 -23000.0 -0.24 -0.6389 -0.906 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I05 mock treatment 480080.0 26400.0 0.27 449620.0 35400.0 0.37 0.4521 0.9872 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I06 mock treatment 565440.0 112000.0 1.14 443320.0 29100.0 0.31 1.0188 0.8665 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I07 compound treatment 427040.0 -26700.0 -0.27 406360.0 -7810.0 -0.08 -0.2495 -0.8813 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I08 compound treatment 450470.0 -3240.0 -0.03 435240.0 21100.0 0.22 0.1328 0.5952 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I09 compound treatment 402470.0 -51200.0 -0.52 362340.0 -51800.0 -0.54 -0.7522 -0.9998 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I10 compound treatment 458310.0 4600.0 0.05 425540.0 11400.0 0.12 0.1173 0.9166 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I11 compound treatment 412000.0 -41700.0 -0.42 323450.0 -90700.0 -0.95 -0.9718 -0.9338 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I12 compound treatment 384420.0 -69300.0 -0.7 378890.0 -35300.0 -0.37 -0.7593 -0.9548 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I13 compound treatment 457990.0 4280.0 0.04 419750.0 5580.0 0.06 0.0721 0.9894 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I14 compound treatment 436840.0 -16900.0 -0.17 378830.0 -35300.0 -0.37 -0.383 -0.9387 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I15 compound treatment 491770.0 38100.0 0.39 398460.0 -15700.0 -0.16 0.1571 0.3737 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I16 compound treatment 430410.0 -23300.0 -0.24 396070.0 -18100.0 -0.19 -0.3015 -0.994 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I17 compound treatment 397120.0 -56600.0 -0.58 368450.0 -45700.0 -0.48 -0.7454 -0.9959 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I18 compound treatment 522670.0 69000.0 0.7 449320.0 35100.0 0.37 0.756 0.9549 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I19 compound treatment 503380.0 49700.0 0.5 424360.0 10200.0 0.11 0.4324 0.8381 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I20 compound treatment 464880.0 11200.0 0.11 381050.0 -33100.0 -0.35 -0.1651 -0.4522 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I21 mock treatment 457090.0 3380.0 0.03 479080.0 64900.0 0.68 0.5052 0.7419 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I22 mock treatment 402820.0 -50900.0 -0.52 381170.0 -33000.0 -0.35 -0.6102 -0.9808 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I23 compound treatment 360890.0 -92800.0 -0.94 392910.0 -21300.0 -0.22 -0.8245 -0.8507 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 I24 compound treatment 401210.0 -52500.0 -0.53 404210.0 -9960.0 -0.1 -0.451 -0.8297 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J01 compound treatment 365990.0 -87700.0 -0.89 384660.0 -29500.0 -0.31 -0.8489 -0.8998 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J02 compound treatment 313060.0 -141000.0 -1.43 290880.0 -123000.0 -1.29 -1.9241 -0.9987 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J03 compound treatment 359940.0 -93800.0 -0.95 322440.0 -91700.0 -0.96 -1.3534 -1.0 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J04 compound treatment 453850.0 143.0 0.0 395070.0 -19100.0 -0.2 -0.1405 -0.702 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J05 mock treatment 401940.0 -51800.0 -0.53 443380.0 29200.0 0.31 -0.1556 -0.2556 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J06 mock treatment 485930.0 32200.0 0.33 342400.0 -71800.0 -0.75 -0.3002 -0.366 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J07 compound treatment 493560.0 39900.0 0.4 327680.0 -86500.0 -0.91 -0.3544 -0.3571 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J08 compound treatment 448000.0 -5710.0 -0.06 362970.0 -51200.0 -0.54 -0.4203 -0.779 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J09 compound treatment 365510.0 -88200.0 -0.9 357020.0 -57200.0 -0.6 -1.0572 -0.9808 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J10 compound treatment 433680.0 -20000.0 -0.2 375430.0 -38700.0 -0.41 -0.4309 -0.949 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J11 compound treatment 369160.0 -84500.0 -0.86 323960.0 -90200.0 -0.95 -1.2759 -0.9989 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J12 compound treatment 328440.0 -125000.0 -1.27 251780.0 -162000.0 -1.7 -2.1032 -0.9898 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J13 compound treatment 440650.0 -13100.0 -0.13 368830.0 -45300.0 -0.48 -0.4297 -0.8713 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J14 compound treatment 421500.0 -32200.0 -0.33 342420.0 -71800.0 -0.75 -0.763 -0.9306 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J15 compound treatment 418430.0 -35300.0 -0.36 395940.0 -18200.0 -0.19 -0.3886 -0.9566 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J16 compound treatment 460200.0 6490.0 0.07 388030.0 -26100.0 -0.27 -0.147 -0.5218 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J17 compound treatment 227360.0 -226000.0 -2.3 269120.0 -145000.0 -1.52 -2.7011 -0.9798 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J18 compound treatment 451140.0 -2570.0 -0.03 339800.0 -74400.0 -0.78 -0.5694 -0.7304 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J19 compound treatment 422680.0 -31000.0 -0.32 403040.0 -11100.0 -0.12 -0.3054 -0.9085 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J20 compound treatment 439760.0 -13900.0 -0.14 365940.0 -48200.0 -0.51 -0.4576 -0.8718 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J21 mock treatment 386250.0 -67500.0 -0.69 423620.0 9450.0 0.1 -0.4147 -0.5988 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J22 mock treatment 417280.0 -36400.0 -0.37 390840.0 -23300.0 -0.24 -0.4346 -0.9797 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J23 compound treatment 328550.0 -125000.0 -1.27 408040.0 -6130.0 -0.06 -0.9448 -0.7419 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 J24 compound treatment 354140.0 -99600.0 -1.01 363290.0 -50900.0 -0.53 -1.0924 -0.9552 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K01 compound treatment 417760.0 -35900.0 -0.37 383580.0 -30600.0 -0.32 -0.4849 -0.9979 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K02 compound treatment 429920.0 -23800.0 -0.24 357370.0 -56800.0 -0.6 -0.5918 -0.9212 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K03 compound treatment 465570.0 11900.0 0.12 388410.0 -25800.0 -0.27 -0.1056 -0.3573 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K04 compound treatment 307170.0 -147000.0 -1.49 388080.0 -26100.0 -0.27 -1.2463 -0.8232 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K05 compound treatment 412370.0 -41300.0 -0.42 442290.0 28100.0 0.29 -0.0887 -0.1729 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K06 compound treatment 516960.0 63300.0 0.64 392280.0 -21900.0 -0.23 0.2923 0.4283 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K07 mock treatment 409130.0 -44600.0 -0.45 461070.0 46900.0 0.49 0.0271 0.0406 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K08 mock treatment 469600.0 15900.0 0.16 419850.0 5680.0 0.06 0.1563 0.908 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K09 compound treatment 228640.0 -225000.0 -2.29 192200.0 -222000.0 -2.33 -3.2618 -1.0 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K10 compound treatment 434240.0 -19500.0 -0.2 315700.0 -98500.0 -1.03 -0.8694 -0.8276 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K11 compound treatment 397490.0 -56200.0 -0.57 393150.0 -21000.0 -0.22 -0.5597 -0.9141 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K12 compound treatment 520640.0 66900.0 0.68 351240.0 -62900.0 -0.66 0.0147 0.0155 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K13 compound treatment 414410.0 -39300.0 -0.4 357190.0 -57000.0 -0.6 -0.7045 -0.9809 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K14 compound treatment 490690.0 37000.0 0.38 454770.0 40600.0 0.43 0.5665 0.9981 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K15 mock treatment 442160.0 -11500.0 -0.12 377020.0 -37200.0 -0.39 -0.3582 -0.8811 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K16 mock treatment 537180.0 83500.0 0.85 448890.0 34700.0 0.36 0.857 0.9286 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K17 compound treatment 506450.0 52700.0 0.54 424390.0 10200.0 0.11 0.4547 0.8319 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K18 compound treatment 449180.0 -4530.0 -0.05 427780.0 13600.0 0.14 0.0683 0.4558 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K19 compound treatment 473010.0 19300.0 0.2 443400.0 29200.0 0.31 0.3553 0.9768 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K20 compound treatment 478170.0 24500.0 0.25 423210.0 9040.0 0.09 0.2427 0.9125 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K21 compound treatment 403810.0 -49900.0 -0.51 403940.0 -10200.0 -0.11 -0.4343 -0.8381 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K22 compound treatment 389440.0 -64300.0 -0.65 323520.0 -90700.0 -0.95 -1.1334 -0.9833 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K23 mock treatment 406330.0 -47400.0 -0.48 444750.0 30600.0 0.32 -0.1139 -0.1969 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 K24 mock treatment 451680.0 -2030.0 -0.02 372660.0 -41500.0 -0.43 -0.3221 -0.7398 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L01 compound treatment 311540.0 -142000.0 -1.44 322180.0 -92000.0 -0.96 -1.7031 -0.9806 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L02 compound treatment 347290.0 -106000.0 -1.08 350670.0 -63500.0 -0.67 -1.2351 -0.9728 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L03 compound treatment 101660.0 -352000.0 -3.58 138830.0 -275000.0 -2.88 -4.5696 -0.9943 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L04 compound treatment 471950.0 18200.0 0.19 421810.0 7640.0 0.08 0.1877 0.9295 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L05 compound treatment 421920.0 -31800.0 -0.32 387260.0 -26900.0 -0.28 -0.4278 -0.9977 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L06 compound treatment 423470.0 -30200.0 -0.31 328000.0 -86200.0 -0.9 -0.8557 -0.8972 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L07 mock treatment 518350.0 64600.0 0.66 422050.0 7880.0 0.08 0.5229 0.7898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L08 mock treatment 558410.0 105000.0 1.06 423360.0 9190.0 0.1 0.8204 0.768 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L09 compound treatment 523320.0 69600.0 0.71 404770.0 -9400.0 -0.1 0.4306 0.6028 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L10 compound treatment 486200.0 32500.0 0.33 410280.0 -3890.0 -0.04 0.2047 0.6151 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L11 compound treatment 478830.0 25100.0 0.26 415120.0 949.0 0.01 0.1876 0.7341 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L12 compound treatment 468390.0 14700.0 0.15 432750.0 18600.0 0.19 0.2432 0.9914 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L13 compound treatment 454880.0 1170.0 0.01 484160.0 70000.0 0.73 0.527 0.7185 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L14 compound treatment 524880.0 71200.0 0.72 451680.0 37500.0 0.39 0.7893 0.9589 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L15 mock treatment 469890.0 16200.0 0.16 447290.0 33100.0 0.35 0.3617 0.9418 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L16 mock treatment 543920.0 90200.0 0.92 392850.0 -21300.0 -0.22 0.4903 0.5196 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L17 compound treatment 477360.0 23700.0 0.24 450580.0 36400.0 0.38 0.4397 0.9752 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L18 compound treatment 445890.0 -7820.0 -0.08 443940.0 29800.0 0.31 0.1644 0.5107 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L19 compound treatment 432670.0 -21000.0 -0.21 395450.0 -18700.0 -0.2 -0.2899 -0.9991 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L20 compound treatment 292910.0 -161000.0 -1.63 311540.0 -103000.0 -1.08 -1.9158 -0.9794 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L21 compound treatment 445560.0 -8150.0 -0.08 420350.0 6180.0 0.06 -0.0128 -0.1215 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L22 compound treatment 454130.0 423.0 0.0 368170.0 -46000.0 -0.48 -0.3378 -0.7008 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L23 mock treatment 527050.0 73300.0 0.75 402470.0 -11700.0 -0.12 0.4403 0.583 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 L24 mock treatment 431160.0 -22500.0 -0.23 429660.0 15500.0 0.16 -0.0473 -0.1683 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M01 compound treatment 340000.0 -114000.0 -1.16 403050.0 -11100.0 -0.12 -0.8995 -0.7745 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M02 compound treatment 478560.0 24900.0 0.25 449410.0 35200.0 0.37 0.4397 0.9828 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M03 compound treatment 314810.0 -139000.0 -1.41 363580.0 -50600.0 -0.53 -1.3729 -0.9106 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M04 compound treatment 328700.0 -125000.0 -1.27 337040.0 -77100.0 -0.81 -1.4697 -0.9762 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M05 compound treatment 485020.0 31300.0 0.32 473410.0 59200.0 0.62 0.6639 0.9518 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M06 compound treatment 428960.0 -24700.0 -0.25 446210.0 32000.0 0.34 0.0595 0.142 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M07 compound treatment 386600.0 -67100.0 -0.68 347840.0 -66300.0 -0.69 -0.9736 -1.0 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M08 compound treatment 418670.0 -35000.0 -0.36 425960.0 11800.0 0.12 -0.1644 -0.4363 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M09 mock treatment 469920.0 16200.0 0.16 436550.0 22400.0 0.23 0.2823 0.9851 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M10 mock treatment 447890.0 -5820.0 -0.06 463240.0 49100.0 0.51 0.3217 0.6217 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M11 compound treatment 383310.0 -70400.0 -0.72 317820.0 -96400.0 -1.01 -1.2197 -0.9858 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M12 compound treatment 260560.0 -193000.0 -1.96 161870.0 -252000.0 -2.64 -3.2571 -0.9893 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M13 mock treatment 495390.0 41700.0 0.42 405920.0 -8250.0 -0.09 0.2384 0.5514 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M14 mock treatment 480290.0 26600.0 0.27 427200.0 13000.0 0.14 0.2875 0.95 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M15 compound treatment 426730.0 -27000.0 -0.27 428100.0 13900.0 0.15 -0.0907 -0.2919 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M16 compound treatment 456180.0 2470.0 0.03 443480.0 29300.0 0.31 0.2349 0.7624 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M17 compound treatment 339360.0 -114000.0 -1.16 318620.0 -95600.0 -1.0 -1.5296 -0.9972 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M18 compound treatment 482620.0 28900.0 0.29 375620.0 -38600.0 -0.4 -0.0779 -0.1559 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M19 compound treatment 18880.0 -435000.0 -4.42 19420.0 -395000.0 -4.14 -6.0491 -0.9995 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M20 compound treatment 431580.0 -22100.0 -0.22 355230.0 -58900.0 -0.62 -0.5957 -0.9064 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M21 compound treatment 431460.0 -22200.0 -0.23 347780.0 -66400.0 -0.7 -0.6517 -0.891 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M22 compound treatment 381520.0 -72200.0 -0.73 324480.0 -89700.0 -0.94 -1.1832 -0.9925 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M23 compound treatment 376710.0 -77000.0 -0.78 368160.0 -46000.0 -0.48 -0.8942 -0.9729 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 M24 compound treatment 383080.0 -70600.0 -0.72 397450.0 -16700.0 -0.18 -0.6314 -0.8546 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N01 compound treatment 443390.0 -10300.0 -0.1 439200.0 25000.0 0.26 0.1113 0.3941 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N02 compound treatment 445680.0 -8030.0 -0.08 401760.0 -12400.0 -0.13 -0.1496 -0.9748 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N03 compound treatment 386410.0 -67300.0 -0.68 355790.0 -58400.0 -0.61 -0.9161 -0.9985 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N04 compound treatment 412640.0 -41100.0 -0.42 419580.0 5410.0 0.06 -0.255 -0.6055 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N05 compound treatment 317140.0 -137000.0 -1.39 337730.0 -76400.0 -0.8 -1.5477 -0.9659 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N06 compound treatment 430410.0 -23300.0 -0.24 424960.0 10800.0 0.11 -0.0875 -0.3334 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N07 compound treatment 379750.0 -74000.0 -0.75 376720.0 -37500.0 -0.39 -0.8089 -0.9541 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N08 compound treatment 490360.0 36700.0 0.37 382560.0 -31600.0 -0.33 0.0292 0.0585 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N09 mock treatment 428990.0 -24700.0 -0.25 448480.0 34300.0 0.36 0.0766 0.1746 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N10 mock treatment 512290.0 58600.0 0.6 426960.0 12800.0 0.13 0.5157 0.8451 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N11 compound treatment 476960.0 23300.0 0.24 447840.0 33700.0 0.35 0.4165 0.981 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N12 compound treatment 424410.0 -29300.0 -0.3 349990.0 -64200.0 -0.67 -0.686 -0.9328 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N13 mock treatment 538050.0 84300.0 0.86 399250.0 -14900.0 -0.16 0.4955 0.5687 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N14 mock treatment 481090.0 27400.0 0.28 416000.0 1830.0 0.02 0.2103 0.754 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N15 compound treatment 463120.0 9410.0 0.1 392650.0 -21500.0 -0.23 -0.0918 -0.3748 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N16 compound treatment 433040.0 -20700.0 -0.21 359370.0 -54800.0 -0.57 -0.5545 -0.907 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N17 compound treatment 505680.0 52000.0 0.53 370720.0 -43500.0 -0.46 0.0515 0.0739 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N18 compound treatment 473090.0 19400.0 0.2 370580.0 -43600.0 -0.46 -0.1837 -0.3693 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N19 compound treatment 416560.0 -37100.0 -0.38 384550.0 -29600.0 -0.31 -0.4864 -0.9953 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N20 compound treatment 390670.0 -63000.0 -0.64 390420.0 -23800.0 -0.25 -0.6289 -0.9152 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N21 compound treatment 405930.0 -47800.0 -0.49 359410.0 -54800.0 -0.57 -0.749 -0.9965 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N22 compound treatment 483210.0 29500.0 0.3 355860.0 -58300.0 -0.61 -0.22 -0.3233 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N23 compound treatment 461080.0 7370.0 0.07 365770.0 -48400.0 -0.51 -0.3056 -0.5962 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 N24 compound treatment 325120.0 -129000.0 -1.31 345210.0 -69000.0 -0.72 -1.4349 -0.961 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O01 compound treatment 460500.0 6790.0 0.07 464760.0 50600.0 0.53 0.4236 0.7925 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O02 compound treatment 350580.0 -103000.0 -1.05 366500.0 -47700.0 -0.5 -1.0942 -0.9425 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O03 compound treatment 379310.0 -74400.0 -0.76 459890.0 45700.0 0.48 -0.1959 -0.2189 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O04 compound treatment 317830.0 -136000.0 -1.38 311530.0 -103000.0 -1.08 -1.7368 -0.9924 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O05 compound treatment 432740.0 -21000.0 -0.21 432000.0 17800.0 0.19 -0.0186 -0.0655 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O06 compound treatment 443170.0 -10500.0 -0.11 409480.0 -4690.0 -0.05 -0.1105 -0.9376 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O07 compound treatment 448320.0 -5390.0 -0.05 430180.0 16000.0 0.17 0.0799 0.4528 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O08 compound treatment 400920.0 -52800.0 -0.54 384050.0 -30100.0 -0.32 -0.6025 -0.968 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O09 compound treatment 417470.0 -36200.0 -0.37 395720.0 -18500.0 -0.19 -0.3971 -0.9548 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O10 compound treatment 457700.0 3990.0 0.04 368060.0 -46100.0 -0.48 -0.3129 -0.6455 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O11 mock treatment 523240.0 69500.0 0.71 395760.0 -18400.0 -0.19 0.3632 0.4959 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O12 mock treatment 464820.0 11100.0 0.11 442770.0 28600.0 0.3 0.2917 0.911 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O13 compound treatment 383330.0 -70400.0 -0.72 378840.0 -35300.0 -0.37 -0.7675 -0.953 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O14 compound treatment 432960.0 -20700.0 -0.21 354560.0 -59600.0 -0.62 -0.5907 -0.8961 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O15 compound treatment 468490.0 14800.0 0.15 408800.0 -5370.0 -0.06 0.0664 0.4141 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O16 compound treatment 480200.0 26500.0 0.27 336800.0 -77400.0 -0.81 -0.3829 -0.4482 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O17 compound treatment 455610.0 1900.0 0.02 419850.0 5680.0 0.06 0.0557 0.891 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O18 compound treatment 437960.0 -15700.0 -0.16 387910.0 -26300.0 -0.28 -0.3077 -0.9667 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O19 compound treatment 321370.0 -132000.0 -1.34 246950.0 -167000.0 -1.75 -2.1898 -0.9915 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O20 compound treatment 384130.0 -69600.0 -0.71 327080.0 -87100.0 -0.91 -1.1452 -0.9921 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O21 compound treatment 367620.0 -86100.0 -0.87 303220.0 -111000.0 -1.16 -1.4406 -0.9902 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O22 compound treatment 337790.0 -116000.0 -1.18 317870.0 -96300.0 -1.01 -1.5464 -0.997 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O23 compound treatment 287690.0 -166000.0 -1.69 256680.0 -157000.0 -1.65 -2.3598 -0.9999 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 O24 compound treatment 402530.0 -51200.0 -0.52 350410.0 -63800.0 -0.67 -0.8401 -0.9923 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P01 compound treatment 237730.0 -216000.0 -2.19 253600.0 -161000.0 -1.68 -2.7416 -0.9914 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P02 compound treatment 388200.0 -65500.0 -0.67 373870.0 -40300.0 -0.42 -0.7693 -0.9759 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P03 compound treatment 421670.0 -32000.0 -0.33 376570.0 -37600.0 -0.39 -0.5088 -0.9955 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P04 compound treatment 436690.0 -17000.0 -0.17 336740.0 -77400.0 -0.81 -0.6959 -0.839 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P05 compound treatment 361120.0 -92600.0 -0.94 51950.0 -362000.0 -3.8 -3.3489 -0.8565 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P06 compound treatment 363930.0 -89800.0 -0.91 324200.0 -90000.0 -0.94 -1.3117 -0.9999 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P07 compound treatment 303200.0 -151000.0 -1.53 339210.0 -75000.0 -0.79 -1.6369 -0.952 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P08 compound treatment 408320.0 -45400.0 -0.46 379750.0 -34400.0 -0.36 -0.5812 -0.9926 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P09 compound treatment 348160.0 -106000.0 -1.07 358740.0 -55400.0 -0.58 -1.1691 -0.9585 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P10 compound treatment 458350.0 4640.0 0.05 388970.0 -25200.0 -0.26 -0.1533 -0.5717 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P11 mock treatment 396960.0 -56700.0 -0.58 341040.0 -73100.0 -0.77 -0.9496 -0.9902 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P12 mock treatment 456840.0 3130.0 0.03 360850.0 -53300.0 -0.56 -0.3725 -0.6657 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P13 compound treatment 414580.0 -39100.0 -0.4 361850.0 -52300.0 -0.55 -0.6688 -0.9876 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P14 compound treatment 375220.0 -78500.0 -0.8 350240.0 -63900.0 -0.67 -1.0376 -0.9962 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P15 compound treatment 413550.0 -40200.0 -0.41 401800.0 -12400.0 -0.13 -0.3802 -0.888 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P16 compound treatment 355200.0 -98500.0 -1.0 331000.0 -83200.0 -0.87 -1.324 -0.9976 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P17 compound treatment 386930.0 -66800.0 -0.68 371680.0 -42500.0 -0.45 -0.7946 -0.9791 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P18 compound treatment 126480.0 -327000.0 -3.33 151200.0 -263000.0 -2.76 -4.2996 -0.9956 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P19 compound treatment 350690.0 -103000.0 -1.05 306770.0 -107000.0 -1.13 -1.536 -0.9993 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P20 compound treatment 348330.0 -105000.0 -1.07 275290.0 -139000.0 -1.46 -1.7861 -0.9886 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P21 compound treatment 299200.0 -155000.0 -1.57 321600.0 -92600.0 -0.97 -1.7961 -0.9732 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P22 compound treatment 391370.0 -62300.0 -0.63 309970.0 -104000.0 -1.09 -1.2199 -0.9665 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P23 compound treatment 382410.0 -71300.0 -0.72 331890.0 -82300.0 -0.86 -1.1219 -0.9963 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2097 P24 compound treatment 391680.0 -62000.0 -0.63 353440.0 -60700.0 -0.64 -0.8956 -1.0 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A01 compound treatment 456490.0 9060.0 0.09 454920.0 20100.0 0.21 0.2138 0.9314 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A02 compound treatment 424340.0 -23100.0 -0.23 392110.0 -42700.0 -0.45 -0.4825 -0.9545 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A03 compound treatment 424710.0 -22700.0 -0.23 311440.0 -123000.0 -1.29 -1.0775 -0.8204 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A04 compound treatment 524700.0 77300.0 0.79 447040.0 12200.0 0.13 0.6456 0.8115 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A05 compound treatment 306370.0 -141000.0 -1.43 322820.0 -112000.0 -1.17 -1.8436 -0.9951 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A06 compound treatment 362420.0 -85000.0 -0.86 388920.0 -45900.0 -0.48 -0.9511 -0.9618 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A07 compound treatment 451550.0 4120.0 0.04 392050.0 -42800.0 -0.45 -0.2875 -0.6383 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A08 compound treatment 360820.0 -86600.0 -0.88 354630.0 -80200.0 -0.84 -1.2167 -0.9997 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A09 compound treatment 440980.0 -6450.0 -0.07 396350.0 -38500.0 -0.4 -0.3316 -0.8113 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A10 compound treatment 425540.0 -21900.0 -0.22 376430.0 -58400.0 -0.61 -0.5901 -0.9061 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A11 compound treatment 347200.0 -100000.0 -1.02 334280.0 -101000.0 -1.05 -1.4653 -0.9999 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A12 compound treatment 354160.0 -93300.0 -0.95 368220.0 -66600.0 -0.7 -1.1638 -0.9887 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A13 mock treatment 459700.0 12300.0 0.12 409290.0 -25600.0 -0.27 -0.1012 -0.3425 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A14 mock treatment 412800.0 -34600.0 -0.35 331110.0 -104000.0 -1.09 -1.0174 -0.8905 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A15 compound treatment 449310.0 1880.0 0.02 381290.0 -53600.0 -0.56 -0.3833 -0.6826 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A16 compound treatment 394740.0 -52700.0 -0.54 349390.0 -85500.0 -0.9 -1.0117 -0.9698 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A17 compound treatment 418290.0 -29100.0 -0.3 410170.0 -24700.0 -0.26 -0.3922 -0.9977 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A18 compound treatment 300820.0 -147000.0 -1.49 343750.0 -91100.0 -0.95 -1.7284 -0.9768 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A19 compound treatment 394240.0 -53200.0 -0.54 408220.0 -26600.0 -0.28 -0.5795 -0.9527 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A20 compound treatment 398910.0 -48500.0 -0.49 395600.0 -39300.0 -0.41 -0.6394 -0.9959 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A21 compound treatment 368560.0 -78900.0 -0.8 331530.0 -103000.0 -1.08 -1.3322 -0.9891 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A22 compound treatment 434800.0 -12600.0 -0.13 369280.0 -65600.0 -0.69 -0.5765 -0.8249 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A23 compound treatment 404860.0 -42600.0 -0.43 384160.0 -50700.0 -0.53 -0.6814 -0.9948 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 A24 compound treatment 304960.0 -142000.0 -1.45 286850.0 -148000.0 -1.55 -2.1202 -0.9994 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B01 compound treatment 343420.0 -104000.0 -1.06 372970.0 -61900.0 -0.65 -1.2058 -0.9725 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B02 compound treatment 482740.0 35300.0 0.36 531040.0 96200.0 1.01 0.9664 0.9033 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B03 compound treatment 456180.0 8750.0 0.09 414560.0 -20300.0 -0.21 -0.0874 -0.3794 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B04 compound treatment 447680.0 253.0 0.0 419320.0 -15500.0 -0.16 -0.1132 -0.6958 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B05 compound treatment 506600.0 59200.0 0.6 478670.0 43800.0 0.46 0.7499 0.9911 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B06 compound treatment 381200.0 -66200.0 -0.67 358810.0 -76000.0 -0.8 -1.0392 -0.9965 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B07 compound treatment 450600.0 3170.0 0.03 405780.0 -29100.0 -0.3 -0.1926 -0.6287 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B08 compound treatment 377690.0 -69700.0 -0.71 440990.0 6140.0 0.06 -0.4556 -0.6403 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B09 compound treatment 478560.0 31100.0 0.32 466880.0 32000.0 0.34 0.461 0.9996 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B10 compound treatment 429850.0 -17600.0 -0.18 414140.0 -20700.0 -0.22 -0.2797 -0.9953 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B11 compound treatment 448230.0 803.0 0.01 478690.0 43800.0 0.46 0.3306 0.7196 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B12 compound treatment 344510.0 -103000.0 -1.05 381180.0 -53700.0 -0.56 -1.1372 -0.9577 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B13 mock treatment 490570.0 43100.0 0.44 428380.0 -6470.0 -0.07 0.2621 0.5908 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B14 mock treatment 486720.0 39300.0 0.4 548970.0 114000.0 1.2 1.1278 0.8947 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B15 compound treatment 370810.0 -76600.0 -0.78 389700.0 -45200.0 -0.47 -0.885 -0.9715 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B16 compound treatment 477700.0 30300.0 0.31 393920.0 -40900.0 -0.43 -0.0857 -0.1624 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B17 compound treatment 385390.0 -62000.0 -0.63 405680.0 -29200.0 -0.31 -0.6619 -0.9447 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B18 compound treatment 418410.0 -29000.0 -0.29 399680.0 -35200.0 -0.37 -0.4691 -0.9939 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B19 compound treatment 398150.0 -49300.0 -0.5 449050.0 14200.0 0.15 -0.2489 -0.4764 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B20 compound treatment 314740.0 -133000.0 -1.35 266890.0 -168000.0 -1.76 -2.1978 -0.9914 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B21 compound treatment 432240.0 -15200.0 -0.15 384010.0 -50800.0 -0.53 -0.4858 -0.8759 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B22 compound treatment 424720.0 -22700.0 -0.23 417280.0 -17600.0 -0.18 -0.2933 -0.9937 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B23 compound treatment 429710.0 -17700.0 -0.18 386940.0 -47900.0 -0.5 -0.4823 -0.9043 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 B24 compound treatment 477720.0 30300.0 0.31 493010.0 58200.0 0.61 0.6486 0.95 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C01 compound treatment 431890.0 -15500.0 -0.16 423750.0 -11100.0 -0.12 -0.1939 -0.9887 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C02 compound treatment 391930.0 -55500.0 -0.56 363850.0 -71000.0 -0.74 -0.9248 -0.9907 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C03 compound treatment 436320.0 -11100.0 -0.11 352070.0 -82800.0 -0.87 -0.6931 -0.7924 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C04 compound treatment 265610.0 -182000.0 -1.85 301010.0 -134000.0 -1.4 -2.2981 -0.9907 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C05 compound treatment 405140.0 -42300.0 -0.43 318910.0 -116000.0 -1.21 -1.1628 -0.9024 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C06 compound treatment 432920.0 -14500.0 -0.15 395170.0 -39700.0 -0.42 -0.3982 -0.9028 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C07 compound treatment 483630.0 36200.0 0.37 412560.0 -22300.0 -0.23 0.095 0.218 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C08 compound treatment 476480.0 29100.0 0.3 386320.0 -48500.0 -0.51 -0.1508 -0.2564 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C09 compound treatment 271490.0 -176000.0 -1.79 239780.0 -195000.0 -2.04 -2.7094 -0.9978 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C10 compound treatment 347360.0 -100000.0 -1.02 242960.0 -192000.0 -2.01 -2.1407 -0.9501 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C11 mock treatment 387640.0 -59800.0 -0.61 412600.0 -22300.0 -0.23 -0.5945 -0.9135 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C12 mock treatment 338530.0 -109000.0 -1.11 273830.0 -161000.0 -1.69 -1.9755 -0.9791 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C13 compound treatment 330240.0 -117000.0 -1.19 284340.0 -151000.0 -1.58 -1.9572 -0.9904 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C14 compound treatment 376960.0 -70500.0 -0.72 374020.0 -60800.0 -0.64 -0.957 -0.9983 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C15 mock treatment 440600.0 -6830.0 -0.07 402520.0 -32300.0 -0.34 -0.2886 -0.8346 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C16 mock treatment 396360.0 -51100.0 -0.52 400260.0 -34600.0 -0.36 -0.6232 -0.9846 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C17 compound treatment 362370.0 -85100.0 -0.86 431170.0 -3680.0 -0.04 -0.6385 -0.7379 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C18 compound treatment 363200.0 -84200.0 -0.86 391360.0 -43500.0 -0.46 -0.9274 -0.9565 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C19 compound treatment 344000.0 -103000.0 -1.05 361600.0 -73300.0 -0.77 -1.2859 -0.9881 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C20 compound treatment 394400.0 -53000.0 -0.54 374400.0 -60500.0 -0.63 -0.8289 -0.9968 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C21 compound treatment 319220.0 -128000.0 -1.3 320560.0 -114000.0 -1.2 -1.768 -0.9991 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C22 compound treatment 431900.0 -15500.0 -0.16 392750.0 -42100.0 -0.44 -0.4235 -0.9039 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C23 compound treatment 371360.0 -76100.0 -0.77 370130.0 -64700.0 -0.68 -1.0261 -0.9979 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 C24 compound treatment 428380.0 -19000.0 -0.19 394560.0 -40300.0 -0.42 -0.4354 -0.9375 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D01 compound treatment 445160.0 -2270.0 -0.02 468060.0 33200.0 0.35 0.2298 0.6589 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D02 compound treatment 389390.0 -58000.0 -0.59 380420.0 -54400.0 -0.57 -0.8203 -0.9999 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D03 compound treatment 498170.0 50700.0 0.52 409390.0 -25500.0 -0.27 0.176 0.3031 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D04 compound treatment 479630.0 32200.0 0.33 442570.0 7720.0 0.08 0.2886 0.8561 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D05 compound treatment 403770.0 -43700.0 -0.44 348660.0 -86200.0 -0.9 -0.9523 -0.9464 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D06 compound treatment 315840.0 -132000.0 -1.34 255840.0 -179000.0 -1.88 -2.2718 -0.9862 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D07 compound treatment 416730.0 -30700.0 -0.31 338900.0 -96000.0 -1.01 -0.9314 -0.8849 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D08 compound treatment 479400.0 32000.0 0.32 395580.0 -39300.0 -0.41 -0.0612 -0.1167 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D09 compound treatment 420870.0 -26600.0 -0.27 422400.0 -12500.0 -0.13 -0.2831 -0.9444 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D10 compound treatment 331900.0 -116000.0 -1.17 255690.0 -179000.0 -1.88 -2.1575 -0.9745 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D11 mock treatment 460580.0 13200.0 0.13 354050.0 -80800.0 -0.85 -0.5041 -0.5882 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D12 mock treatment 408500.0 -38900.0 -0.4 466620.0 31800.0 0.33 -0.0443 -0.0858 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D13 compound treatment 429720.0 -17700.0 -0.18 434160.0 -690.0 -0.01 -0.1323 -0.7349 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D14 compound treatment 346720.0 -101000.0 -1.02 379100.0 -55800.0 -0.58 -1.1367 -0.9646 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D15 mock treatment 399680.0 -47700.0 -0.49 481400.0 46600.0 0.49 0.0018 0.0026 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D16 mock treatment 393390.0 -54000.0 -0.55 366930.0 -67900.0 -0.71 -0.8915 -0.9918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D17 compound treatment 434940.0 -12500.0 -0.13 371580.0 -63300.0 -0.66 -0.5585 -0.8274 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D18 compound treatment 489890.0 42500.0 0.43 423100.0 -11800.0 -0.12 0.2181 0.486 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D19 compound treatment 433860.0 -13600.0 -0.14 450690.0 15800.0 0.17 0.0199 0.0921 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D20 compound treatment 436430.0 -11000.0 -0.11 432890.0 -1960.0 -0.02 -0.0935 -0.8233 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D21 compound treatment 360420.0 -87000.0 -0.88 335440.0 -99400.0 -1.04 -1.3617 -0.9967 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D22 compound treatment 424290.0 -23100.0 -0.24 370950.0 -63900.0 -0.67 -0.6397 -0.9015 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D23 compound treatment 423740.0 -23700.0 -0.24 409300.0 -25600.0 -0.27 -0.3595 -0.9986 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 D24 compound treatment 435080.0 -12300.0 -0.13 372000.0 -62900.0 -0.66 -0.5544 -0.827 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E01 mock treatment 454040.0 6610.0 0.07 402810.0 -32000.0 -0.34 -0.1899 -0.5545 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E02 mock treatment 420610.0 -26800.0 -0.27 481570.0 46700.0 0.49 0.1534 0.2739 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E03 compound treatment 390720.0 -56700.0 -0.58 414190.0 -20700.0 -0.22 -0.5605 -0.9106 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E04 compound treatment 533250.0 85800.0 0.87 442360.0 7510.0 0.08 0.6723 0.7678 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E05 compound treatment 427940.0 -19500.0 -0.2 429410.0 -5440.0 -0.06 -0.1803 -0.8751 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E06 compound treatment 381160.0 -66300.0 -0.67 260480.0 -174000.0 -1.83 -1.768 -0.908 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E07 compound treatment 445760.0 -1670.0 -0.02 357930.0 -76900.0 -0.81 -0.5819 -0.7218 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E08 compound treatment 442520.0 -4910.0 -0.05 360910.0 -73900.0 -0.77 -0.5831 -0.7511 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E09 mock treatment 538790.0 91400.0 0.93 469530.0 34700.0 0.36 0.9134 0.9162 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E10 mock treatment 462480.0 15100.0 0.15 474980.0 40100.0 0.42 0.4055 0.9063 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E11 compound treatment 468430.0 21000.0 0.21 441050.0 6200.0 0.06 0.1969 0.8824 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E12 compound treatment 277440.0 -170000.0 -1.73 313440.0 -121000.0 -1.27 -2.121 -0.9887 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E13 compound treatment 410680.0 -36700.0 -0.37 451520.0 16700.0 0.17 -0.1405 -0.3409 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E14 compound treatment 443290.0 -4140.0 -0.04 412640.0 -22200.0 -0.23 -0.1943 -0.8215 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E15 compound treatment 465440.0 18000.0 0.18 415470.0 -19400.0 -0.2 -0.0141 -0.0517 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E16 compound treatment 419240.0 -28200.0 -0.29 387620.0 -47200.0 -0.49 -0.5525 -0.9662 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E17 mock treatment 478370.0 30900.0 0.31 432080.0 -2770.0 -0.03 0.2018 0.6391 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E18 mock treatment 457370.0 9940.0 0.1 499360.0 64500.0 0.68 0.5494 0.8039 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E19 compound treatment 375160.0 -72300.0 -0.73 375130.0 -59700.0 -0.63 -0.9617 -0.9968 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E20 compound treatment 456000.0 8570.0 0.09 453530.0 18700.0 0.2 0.2 0.9336 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E21 compound treatment 432690.0 -14700.0 -0.15 403420.0 -31400.0 -0.33 -0.3387 -0.9364 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E22 compound treatment 379590.0 -67800.0 -0.69 396510.0 -38300.0 -0.4 -0.7715 -0.967 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E23 compound treatment 418890.0 -28500.0 -0.29 369070.0 -65800.0 -0.69 -0.6924 -0.926 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 E24 compound treatment 435950.0 -11500.0 -0.12 378960.0 -55900.0 -0.59 -0.4965 -0.8316 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F01 mock treatment 480750.0 33300.0 0.34 450660.0 15800.0 0.17 0.3566 0.9459 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F02 mock treatment 492360.0 44900.0 0.46 505670.0 70800.0 0.74 0.8476 0.9728 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F03 compound treatment 467720.0 20300.0 0.21 398430.0 -36400.0 -0.38 -0.124 -0.2859 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F04 compound treatment 466400.0 19000.0 0.19 456260.0 21400.0 0.22 0.295 0.9972 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F05 compound treatment 395360.0 -52100.0 -0.53 350960.0 -83900.0 -0.88 -0.9957 -0.9705 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F06 compound treatment 435600.0 -11800.0 -0.12 447390.0 12500.0 0.13 0.0079 0.0445 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F07 compound treatment 367170.0 -80300.0 -0.82 413240.0 -21600.0 -0.23 -0.7368 -0.8705 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F08 compound treatment 439920.0 -7510.0 -0.08 360580.0 -74300.0 -0.78 -0.6042 -0.7727 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F09 mock treatment 456420.0 8990.0 0.09 403920.0 -30900.0 -0.32 -0.1645 -0.4886 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F10 mock treatment 521490.0 74100.0 0.75 403170.0 -31700.0 -0.33 0.2975 0.3617 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F11 compound treatment 432180.0 -15200.0 -0.15 451130.0 16300.0 0.17 0.0111 0.048 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F12 compound treatment 426150.0 -21300.0 -0.22 440490.0 5640.0 0.06 -0.1111 -0.4957 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F13 compound treatment 406190.0 -41200.0 -0.42 398780.0 -36100.0 -0.38 -0.5635 -0.9987 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F14 compound treatment 426450.0 -21000.0 -0.21 435130.0 280.0 0.0 -0.1487 -0.6973 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F15 compound treatment 392990.0 -54400.0 -0.55 311360.0 -123000.0 -1.29 -1.3061 -0.9282 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F16 compound treatment 416110.0 -31300.0 -0.32 384800.0 -50100.0 -0.52 -0.5958 -0.9714 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F17 mock treatment 433440.0 -14000.0 -0.14 418500.0 -16400.0 -0.17 -0.2216 -0.9957 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F18 mock treatment 435390.0 -12000.0 -0.12 419240.0 -15600.0 -0.16 -0.2021 -0.9898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F19 compound treatment 359240.0 -88200.0 -0.9 352760.0 -82100.0 -0.86 -1.2419 -0.9998 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F20 compound treatment 417820.0 -29600.0 -0.3 411600.0 -23300.0 -0.24 -0.385 -0.9945 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F21 compound treatment 418080.0 -29300.0 -0.3 413360.0 -21500.0 -0.23 -0.3701 -0.9904 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F22 compound treatment 411040.0 -36400.0 -0.37 433710.0 -1140.0 -0.01 -0.2699 -0.7296 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F23 compound treatment 249000.0 -198000.0 -2.02 264890.0 -170000.0 -1.78 -2.685 -0.9981 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 F24 compound treatment 466980.0 19600.0 0.2 467680.0 32800.0 0.34 0.3837 0.966 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G01 compound treatment 352690.0 -94700.0 -0.96 369120.0 -65700.0 -0.69 -1.1677 -0.9865 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G02 compound treatment 433660.0 -13800.0 -0.14 422030.0 -12800.0 -0.13 -0.1939 -0.9998 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G03 mock treatment 377020.0 -70400.0 -0.72 482980.0 48100.0 0.5 -0.1493 -0.1706 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G04 mock treatment 498500.0 51100.0 0.52 438090.0 3240.0 0.03 0.391 0.7518 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G05 compound treatment 423070.0 -24400.0 -0.25 441000.0 6150.0 0.06 -0.1295 -0.5062 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G06 compound treatment 159200.0 -288000.0 -2.93 149180.0 -286000.0 -2.99 -4.1876 -0.9999 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G07 compound treatment 432110.0 -15300.0 -0.16 389340.0 -45500.0 -0.48 -0.4472 -0.8916 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G08 compound treatment 447360.0 -66.6 0.0 376810.0 -58000.0 -0.61 -0.4305 -0.7079 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G09 compound treatment 479040.0 31600.0 0.32 377960.0 -56900.0 -0.6 -0.1943 -0.287 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G10 compound treatment 429530.0 -17900.0 -0.18 398720.0 -36100.0 -0.38 -0.3963 -0.9436 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G11 compound treatment 81200.0 -366000.0 -3.72 47240.0 -388000.0 -4.06 -5.5033 -0.999 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G12 compound treatment 367910.0 -79500.0 -0.81 414670.0 -20200.0 -0.21 -0.7209 -0.8631 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G13 compound treatment 431960.0 -15500.0 -0.16 469820.0 35000.0 0.37 0.1479 0.3711 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G14 compound treatment 479050.0 31600.0 0.32 478810.0 44000.0 0.46 0.5529 0.9845 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G15 compound treatment 489040.0 41600.0 0.42 541930.0 107000.0 1.12 1.0923 0.9111 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G16 compound treatment 393340.0 -54100.0 -0.55 364090.0 -70800.0 -0.74 -0.9129 -0.9891 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G17 compound treatment 290780.0 -157000.0 -1.59 322560.0 -112000.0 -1.18 -1.9575 -0.9889 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G18 compound treatment 495580.0 48200.0 0.49 455730.0 20900.0 0.22 0.5007 0.9341 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G19 mock treatment 431570.0 -15900.0 -0.16 437760.0 2910.0 0.03 -0.0924 -0.5633 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G20 mock treatment 388090.0 -59300.0 -0.6 481780.0 46900.0 0.49 -0.0787 -0.1011 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G21 compound treatment 433310.0 -14100.0 -0.14 458370.0 23500.0 0.25 0.0728 0.2554 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G22 compound treatment 475850.0 28400.0 0.29 437860.0 3010.0 0.03 0.2265 0.7797 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G23 compound treatment 465570.0 18100.0 0.18 425480.0 -9370.0 -0.1 0.061 0.2918 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 G24 compound treatment 460130.0 12700.0 0.13 425930.0 -8920.0 -0.09 0.0252 0.1581 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H01 compound treatment 349470.0 -98000.0 -1.0 347060.0 -87800.0 -0.92 -1.3543 -0.9992 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H02 compound treatment 388260.0 -59200.0 -0.6 427040.0 -7810.0 -0.08 -0.483 -0.796 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H03 mock treatment 377340.0 -70100.0 -0.71 344010.0 -90800.0 -0.95 -1.1766 -0.9898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H04 mock treatment 505540.0 58100.0 0.59 351390.0 -83500.0 -0.87 -0.2007 -0.1902 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H05 compound treatment 409510.0 -37900.0 -0.39 378270.0 -56600.0 -0.59 -0.6916 -0.9782 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H06 compound treatment 535610.0 88200.0 0.9 424770.0 -10100.0 -0.11 0.559 0.6195 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H07 compound treatment 387970.0 -59500.0 -0.6 385530.0 -49300.0 -0.52 -0.7926 -0.997 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H08 compound treatment 557560.0 110000.0 1.12 434630.0 -220.0 0.0 0.7898 0.7056 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H09 compound treatment 430890.0 -16500.0 -0.17 390780.0 -44100.0 -0.46 -0.4453 -0.9063 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H10 compound treatment 422440.0 -25000.0 -0.25 434150.0 -700.0 -0.01 -0.1847 -0.7272 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H11 compound treatment 494440.0 47000.0 0.48 400450.0 -34400.0 -0.36 0.083 0.1386 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H12 compound treatment 349940.0 -97500.0 -0.99 417230.0 -17600.0 -0.18 -0.8311 -0.8247 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H13 compound treatment 531100.0 83700.0 0.85 485860.0 51000.0 0.53 0.9792 0.975 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H14 compound treatment 490580.0 43200.0 0.44 471860.0 37000.0 0.39 0.5843 0.9981 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H15 compound treatment 554160.0 107000.0 1.08 427050.0 -7800.0 -0.08 0.7092 0.652 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H16 compound treatment 394560.0 -52900.0 -0.54 437170.0 2320.0 0.02 -0.3627 -0.6744 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H17 compound treatment 385760.0 -61700.0 -0.63 424910.0 -9940.0 -0.1 -0.5168 -0.8135 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H18 compound treatment 403960.0 -43500.0 -0.44 436060.0 1210.0 0.01 -0.3034 -0.6865 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H19 mock treatment 456930.0 9500.0 0.1 467010.0 32200.0 0.34 0.3066 0.8746 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H20 mock treatment 432180.0 -15200.0 -0.15 410940.0 -23900.0 -0.25 -0.2867 -0.9733 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H21 compound treatment 433930.0 -13500.0 -0.14 421160.0 -13700.0 -0.14 -0.1984 -0.9997 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H22 compound treatment 362440.0 -85000.0 -0.86 379700.0 -55200.0 -0.58 -1.0193 -0.9809 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H23 compound treatment 415900.0 -31500.0 -0.32 404340.0 -30500.0 -0.32 -0.4526 -1.0 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 H24 compound treatment 437780.0 -9650.0 -0.1 405440.0 -29400.0 -0.31 -0.2872 -0.8882 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I01 compound treatment 355910.0 -91500.0 -0.93 362430.0 -72400.0 -0.76 -1.1941 -0.9949 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I02 compound treatment 433330.0 -14100.0 -0.14 363590.0 -71300.0 -0.75 -0.6292 -0.8277 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I03 compound treatment 359720.0 -87700.0 -0.89 349600.0 -85300.0 -0.89 -1.2618 -1.0 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I04 compound treatment 333920.0 -114000.0 -1.15 325760.0 -109000.0 -1.14 -1.6238 -1.0 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I05 mock treatment 445970.0 -1460.0 -0.01 400960.0 -33900.0 -0.36 -0.2615 -0.7359 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I06 mock treatment 414640.0 -32800.0 -0.33 435790.0 940.0 0.01 -0.2286 -0.6859 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I07 compound treatment 521860.0 74400.0 0.76 419560.0 -15300.0 -0.16 0.4216 0.5453 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I08 compound treatment 460190.0 12800.0 0.13 429470.0 -5380.0 -0.06 0.0519 0.3667 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I09 compound treatment 428320.0 -19100.0 -0.19 371880.0 -63000.0 -0.66 -0.6038 -0.878 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I10 compound treatment 436850.0 -10600.0 -0.11 388710.0 -46100.0 -0.48 -0.4178 -0.8437 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I11 compound treatment 389500.0 -57900.0 -0.59 354110.0 -80700.0 -0.85 -1.0144 -0.9843 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I12 compound treatment 335840.0 -112000.0 -1.13 335710.0 -99100.0 -1.04 -1.5363 -0.999 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I13 compound treatment 443290.0 -4140.0 -0.04 412050.0 -22800.0 -0.24 -0.1986 -0.819 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I14 compound treatment 301650.0 -146000.0 -1.48 383150.0 -51700.0 -0.54 -1.4305 -0.9069 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I15 compound treatment 363330.0 -84100.0 -0.85 228410.0 -206000.0 -2.16 -2.1337 -0.9175 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I16 compound treatment 406850.0 -40600.0 -0.41 402720.0 -32100.0 -0.34 -0.5296 -0.9949 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I17 compound treatment 435210.0 -12200.0 -0.12 493340.0 58500.0 0.61 0.3456 0.5526 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I18 compound treatment 297600.0 -150000.0 -1.52 299850.0 -135000.0 -1.41 -2.0768 -0.9993 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I19 compound treatment 460840.0 13400.0 0.14 498810.0 64000.0 0.67 0.5702 0.8339 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I20 compound treatment 451470.0 4040.0 0.04 474760.0 39900.0 0.42 0.3247 0.7729 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I21 mock treatment 423400.0 -24000.0 -0.24 437410.0 2560.0 0.03 -0.1537 -0.6257 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I22 mock treatment 429480.0 -17900.0 -0.18 429450.0 -5400.0 -0.06 -0.169 -0.8849 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I23 compound treatment 309600.0 -138000.0 -1.4 324230.0 -111000.0 -1.16 -1.8099 -0.9956 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 I24 compound treatment 456070.0 8640.0 0.09 403800.0 -31100.0 -0.33 -0.1679 -0.4983 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J01 compound treatment 321280.0 -126000.0 -1.28 378450.0 -56400.0 -0.59 -1.3243 -0.9382 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J02 compound treatment 354790.0 -92600.0 -0.94 359960.0 -74900.0 -0.78 -1.2205 -0.9959 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J03 compound treatment 375780.0 -71600.0 -0.73 403730.0 -31100.0 -0.33 -0.7454 -0.9344 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J04 compound treatment 376390.0 -71000.0 -0.72 322430.0 -112000.0 -1.18 -1.3433 -0.9724 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J05 mock treatment 483150.0 35700.0 0.36 294510.0 -140000.0 -1.47 -0.783 -0.517 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J06 mock treatment 335680.0 -112000.0 -1.14 318150.0 -117000.0 -1.22 -1.6676 -0.9993 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J07 compound treatment 396210.0 -51200.0 -0.52 377990.0 -56900.0 -0.6 -0.7893 -0.9977 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J08 compound treatment 407700.0 -39700.0 -0.4 367850.0 -67000.0 -0.7 -0.7818 -0.9655 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J09 compound treatment 497120.0 49700.0 0.5 374730.0 -60100.0 -0.63 -0.0883 -0.1094 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J10 compound treatment 395580.0 -51800.0 -0.53 471560.0 36700.0 0.38 -0.1006 -0.1542 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J11 compound treatment 481830.0 34400.0 0.35 428160.0 -6690.0 -0.07 0.1976 0.5543 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J12 compound treatment 361530.0 -85900.0 -0.87 332280.0 -103000.0 -1.07 -1.3771 -0.9947 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J13 compound treatment 339720.0 -108000.0 -1.09 373660.0 -61200.0 -0.64 -1.2273 -0.9675 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J14 compound treatment 430980.0 -16400.0 -0.17 399290.0 -35600.0 -0.37 -0.3816 -0.9346 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J15 compound treatment 317400.0 -130000.0 -1.32 313000.0 -122000.0 -1.28 -1.8371 -0.9999 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J16 compound treatment 394210.0 -53200.0 -0.54 438720.0 3870.0 0.04 -0.3537 -0.6523 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J17 compound treatment 424920.0 -22500.0 -0.23 413680.0 -21200.0 -0.22 -0.3186 -0.9999 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J18 compound treatment 406750.0 -40700.0 -0.41 403230.0 -31600.0 -0.33 -0.5266 -0.994 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J19 compound treatment 476220.0 28800.0 0.29 424230.0 -10600.0 -0.11 0.1282 0.4096 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J20 compound treatment 511440.0 64000.0 0.65 432720.0 -2130.0 -0.02 0.4442 0.6824 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J21 mock treatment 456180.0 8750.0 0.09 427540.0 -7310.0 -0.08 0.0087 0.0745 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J22 mock treatment 443360.0 -4070.0 -0.04 417960.0 -16900.0 -0.18 -0.1544 -0.8494 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J23 compound treatment 361550.0 -85900.0 -0.87 385510.0 -49300.0 -0.52 -0.9826 -0.9688 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 J24 compound treatment 441620.0 -5810.0 -0.06 435620.0 770.0 0.01 -0.036 -0.6048 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K01 compound treatment 491070.0 43600.0 0.44 445010.0 10200.0 0.11 0.3889 0.8526 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K02 compound treatment 452080.0 4650.0 0.05 485970.0 51100.0 0.54 0.4122 0.7666 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K03 compound treatment 478400.0 31000.0 0.31 380120.0 -54700.0 -0.57 -0.1829 -0.2796 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K04 compound treatment 421850.0 -25600.0 -0.26 504410.0 69600.0 0.73 0.3316 0.4285 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K05 compound treatment 296250.0 -151000.0 -1.54 218600.0 -216000.0 -2.27 -2.6884 -0.9821 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K06 compound treatment 477300.0 29900.0 0.3 370250.0 -64600.0 -0.68 -0.2639 -0.3558 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K07 mock treatment 539470.0 92000.0 0.94 369090.0 -65800.0 -0.69 0.1742 0.1499 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K08 mock treatment 498240.0 50800.0 0.52 513850.0 79000.0 0.83 0.9504 0.9742 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K09 compound treatment 316010.0 -131000.0 -1.34 288830.0 -146000.0 -1.53 -2.0261 -0.9977 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K10 compound treatment 423220.0 -24200.0 -0.25 477190.0 42300.0 0.44 0.1397 0.2755 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K11 compound treatment 242450.0 -205000.0 -2.08 239900.0 -195000.0 -2.04 -2.9172 -1.0 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K12 compound treatment 416040.0 -31400.0 -0.32 438000.0 3150.0 0.03 -0.2022 -0.6306 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K13 compound treatment 375850.0 -71600.0 -0.73 360960.0 -73900.0 -0.77 -1.0618 -0.9995 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K14 compound treatment 339080.0 -108000.0 -1.1 408540.0 -26300.0 -0.28 -0.9735 -0.8577 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K15 mock treatment 524030.0 76600.0 0.78 531210.0 96400.0 1.01 1.2644 0.9917 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K16 mock treatment 472700.0 25300.0 0.26 479400.0 44600.0 0.47 0.5117 0.9604 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K17 compound treatment 473500.0 26100.0 0.26 498720.0 63900.0 0.67 0.6606 0.9178 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K18 compound treatment 453620.0 6190.0 0.06 475230.0 40400.0 0.42 0.3437 0.8035 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K19 compound treatment 419010.0 -28400.0 -0.29 429760.0 -5090.0 -0.05 -0.2419 -0.8238 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K20 compound treatment 415080.0 -32300.0 -0.33 437560.0 2710.0 0.03 -0.2124 -0.6436 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K21 compound treatment 514880.0 67500.0 0.69 442610.0 7760.0 0.08 0.5422 0.7855 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K22 compound treatment 286120.0 -161000.0 -1.64 435050.0 200.0 0.0 -1.1576 -0.7062 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K23 mock treatment 428520.0 -18900.0 -0.19 442720.0 7870.0 0.08 -0.0776 -0.3709 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 K24 mock treatment 427580.0 -19800.0 -0.2 445760.0 10900.0 0.11 -0.0618 -0.2665 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L01 compound treatment 376570.0 -70900.0 -0.72 327860.0 -107000.0 -1.12 -1.3018 -0.9771 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L02 compound treatment 454740.0 7310.0 0.07 425130.0 -9720.0 -0.1 -0.0195 -0.1544 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L03 compound treatment 48650.0 -399000.0 -4.05 32660.0 -402000.0 -4.21 -5.8452 -0.9998 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L04 compound treatment 462690.0 15300.0 0.16 475840.0 41000.0 0.43 0.4134 0.9053 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L05 compound treatment 396670.0 -50800.0 -0.52 367070.0 -67800.0 -0.71 -0.8669 -0.9877 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L06 compound treatment 415810.0 -31600.0 -0.32 415910.0 -18900.0 -0.2 -0.3675 -0.9732 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L07 mock treatment 449370.0 1940.0 0.02 417790.0 -17100.0 -0.18 -0.1124 -0.6252 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L08 mock treatment 500850.0 53400.0 0.54 392920.0 -41900.0 -0.44 0.0732 0.1049 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L09 compound treatment 439070.0 -8360.0 -0.08 465710.0 30900.0 0.32 0.1686 0.5043 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L10 compound treatment 522600.0 75200.0 0.76 365820.0 -69000.0 -0.72 0.0287 0.0273 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L11 compound treatment 311410.0 -136000.0 -1.38 369440.0 -65400.0 -0.69 -1.462 -0.9476 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L12 compound treatment 395230.0 -52200.0 -0.53 422490.0 -12400.0 -0.13 -0.4666 -0.8546 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L13 compound treatment 500970.0 53500.0 0.54 489060.0 54200.0 0.57 0.7864 0.9998 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L14 compound treatment 467370.0 19900.0 0.2 457120.0 22300.0 0.23 0.3083 0.9975 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L15 mock treatment 496770.0 49300.0 0.5 429520.0 -5330.0 -0.06 0.3151 0.6245 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L16 mock treatment 474040.0 26600.0 0.27 512480.0 77600.0 0.81 0.7664 0.8941 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L17 compound treatment 488730.0 41300.0 0.42 512160.0 77300.0 0.81 0.8696 0.9531 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L18 compound treatment 444670.0 -2760.0 -0.03 474040.0 39200.0 0.41 0.2705 0.6573 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L19 compound treatment 412910.0 -34500.0 -0.35 478080.0 43200.0 0.45 0.0723 0.1261 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L20 compound treatment 453120.0 5690.0 0.06 426990.0 -7860.0 -0.08 -0.0173 -0.1721 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L21 compound treatment 467120.0 19700.0 0.2 457120.0 22300.0 0.23 0.3065 0.9971 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L22 compound treatment 456450.0 9020.0 0.09 446830.0 12000.0 0.13 0.1536 0.9881 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L23 mock treatment 503800.0 56400.0 0.57 491680.0 56800.0 0.6 0.8261 0.9998 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 L24 mock treatment 443380.0 -4050.0 -0.04 486150.0 51300.0 0.54 0.351 0.6511 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M01 compound treatment 442880.0 -4550.0 -0.05 473610.0 38800.0 0.41 0.2545 0.6226 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M02 compound treatment 473920.0 26500.0 0.27 449950.0 15100.0 0.16 0.3022 0.9679 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M03 compound treatment 405120.0 -42300.0 -0.43 403560.0 -31300.0 -0.33 -0.5358 -0.991 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M04 compound treatment 390640.0 -56800.0 -0.58 361000.0 -73900.0 -0.77 -0.9552 -0.9896 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M05 compound treatment 393550.0 -53900.0 -0.55 364800.0 -70100.0 -0.73 -0.9061 -0.9896 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M06 compound treatment 441540.0 -5890.0 -0.06 423410.0 -11400.0 -0.12 -0.1271 -0.9484 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M07 compound treatment 392720.0 -54700.0 -0.56 383770.0 -51100.0 -0.54 -0.7715 -0.9998 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M08 compound treatment 452850.0 5420.0 0.06 445330.0 10500.0 0.11 0.1166 0.9492 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M09 mock treatment 480050.0 32600.0 0.33 378030.0 -56800.0 -0.6 -0.1865 -0.2738 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M10 mock treatment 477920.0 30500.0 0.31 477870.0 43000.0 0.45 0.5378 0.9833 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M11 compound treatment 371490.0 -75900.0 -0.77 377160.0 -57700.0 -0.6 -0.9731 -0.9927 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M12 compound treatment 457530.0 10100.0 0.1 436510.0 1660.0 0.02 0.0849 0.8153 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M13 mock treatment 452280.0 4850.0 0.05 499250.0 64400.0 0.67 0.512 0.7568 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M14 mock treatment 371640.0 -75800.0 -0.77 491900.0 57100.0 0.6 -0.1219 -0.125 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M15 compound treatment 460720.0 13300.0 0.14 456640.0 21800.0 0.23 0.257 0.9686 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M16 compound treatment 519840.0 72400.0 0.74 504240.0 69400.0 0.73 1.0344 1.0 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M17 compound treatment 358520.0 -88900.0 -0.9 429470.0 -5380.0 -0.06 -0.6787 -0.7498 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M18 compound treatment 457300.0 9870.0 0.1 452160.0 17300.0 0.18 0.1992 0.961 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M19 compound treatment 443270.0 -4160.0 -0.04 489920.0 55100.0 0.58 0.3781 0.6536 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M20 compound treatment 455520.0 8090.0 0.08 410100.0 -24800.0 -0.26 -0.1252 -0.4602 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M21 compound treatment 507310.0 59900.0 0.61 484120.0 49300.0 0.52 0.7953 0.9966 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M22 compound treatment 408020.0 -39400.0 -0.4 395600.0 -39300.0 -0.41 -0.574 -0.9999 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M23 compound treatment 473070.0 25600.0 0.26 479900.0 45100.0 0.47 0.518 0.9608 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 M24 compound treatment 375750.0 -71700.0 -0.73 417560.0 -17300.0 -0.18 -0.6431 -0.8569 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N01 compound treatment 324030.0 -123000.0 -1.25 376560.0 -58300.0 -0.61 -1.3185 -0.9453 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N02 compound treatment 410400.0 -37000.0 -0.38 415480.0 -19400.0 -0.2 -0.4096 -0.958 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N03 compound treatment 479590.0 32200.0 0.33 489350.0 54500.0 0.57 0.6349 0.965 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N04 compound treatment 401780.0 -45600.0 -0.46 332240.0 -103000.0 -1.08 -1.0882 -0.9294 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N05 compound treatment 431520.0 -15900.0 -0.16 423040.0 -11800.0 -0.12 -0.2018 -0.9913 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N06 compound treatment 457010.0 9580.0 0.1 359160.0 -75700.0 -0.79 -0.4919 -0.6156 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N07 compound treatment 491480.0 44100.0 0.45 451100.0 16300.0 0.17 0.4369 0.9123 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N08 compound treatment 520910.0 73500.0 0.75 456870.0 22000.0 0.23 0.6912 0.8843 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N09 mock treatment 462250.0 14800.0 0.15 444530.0 9680.0 0.1 0.1782 0.9815 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N10 mock treatment 439680.0 -7750.0 -0.08 410470.0 -24400.0 -0.26 -0.2363 -0.884 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N11 compound treatment 497560.0 50100.0 0.51 451840.0 17000.0 0.18 0.4861 0.9008 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N12 compound treatment 468570.0 21100.0 0.21 436730.0 1880.0 0.02 0.1659 0.7687 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N13 mock treatment 485070.0 37600.0 0.38 459170.0 24300.0 0.25 0.4507 0.9805 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N14 mock treatment 491630.0 44200.0 0.45 451900.0 17100.0 0.18 0.444 0.9184 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N15 compound treatment 460190.0 12800.0 0.13 422330.0 -12500.0 -0.13 -0.001 -0.0057 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N16 compound treatment 479570.0 32100.0 0.33 434560.0 -290.0 0.0 0.2288 0.7005 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N17 compound treatment 389710.0 -57700.0 -0.59 413320.0 -21500.0 -0.23 -0.5742 -0.9138 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N18 compound treatment 392800.0 -54600.0 -0.56 361690.0 -73200.0 -0.77 -0.9346 -0.9874 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N19 compound treatment 337960.0 -109000.0 -1.11 379210.0 -55600.0 -0.58 -1.1988 -0.9545 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N20 compound treatment 415460.0 -32000.0 -0.32 392000.0 -42900.0 -0.45 -0.5472 -0.9874 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N21 compound treatment 454680.0 7250.0 0.07 439420.0 4570.0 0.05 0.086 0.9782 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N22 compound treatment 382640.0 -64800.0 -0.66 352430.0 -82400.0 -0.86 -1.0762 -0.991 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N23 compound treatment 399050.0 -48400.0 -0.49 405280.0 -29600.0 -0.31 -0.5667 -0.9752 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 N24 compound treatment 346340.0 -101000.0 -1.03 330750.0 -104000.0 -1.09 -1.4976 -0.9996 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O01 compound treatment 401190.0 -46200.0 -0.47 453670.0 18800.0 0.2 -0.1928 -0.3784 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O02 compound treatment 375300.0 -72100.0 -0.73 389850.0 -45000.0 -0.47 -0.8517 -0.9772 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O03 compound treatment 437030.0 -10400.0 -0.11 400540.0 -34300.0 -0.36 -0.3289 -0.8778 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O04 compound treatment 389670.0 -57800.0 -0.59 356850.0 -78000.0 -0.82 -0.9929 -0.9868 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O05 compound treatment 456760.0 9330.0 0.09 437610.0 2760.0 0.03 0.0875 0.8826 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O06 compound treatment 458580.0 11200.0 0.11 369440.0 -65400.0 -0.69 -0.4045 -0.5823 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O07 compound treatment 434400.0 -13000.0 -0.13 417440.0 -17400.0 -0.18 -0.2226 -0.9876 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O08 compound treatment 311490.0 -136000.0 -1.38 319650.0 -115000.0 -1.21 -1.8303 -0.9977 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O09 compound treatment 441760.0 -5670.0 -0.06 429610.0 -5240.0 -0.05 -0.0795 -0.9997 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O10 compound treatment 438590.0 -8840.0 -0.09 431310.0 -3540.0 -0.04 -0.0897 -0.9235 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O11 mock treatment 407050.0 -40400.0 -0.41 386090.0 -48800.0 -0.51 -0.6514 -0.9941 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O12 mock treatment 446440.0 -987.0 -0.01 406470.0 -28400.0 -0.3 -0.2173 -0.7305 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O13 compound treatment 494080.0 46700.0 0.47 416160.0 -18700.0 -0.2 0.1968 0.3836 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O14 compound treatment 484890.0 37500.0 0.38 411900.0 -23000.0 -0.24 0.0992 0.2202 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O15 compound treatment 489760.0 42300.0 0.43 482330.0 47500.0 0.5 0.656 0.9974 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O16 compound treatment 462900.0 15500.0 0.16 441120.0 6270.0 0.07 0.1576 0.925 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O17 compound treatment 438030.0 -9400.0 -0.1 439730.0 4880.0 0.05 -0.0314 -0.2896 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O18 compound treatment 417550.0 -29900.0 -0.3 447520.0 12700.0 0.13 -0.1208 -0.3646 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O19 compound treatment 336580.0 -111000.0 -1.13 297520.0 -137000.0 -1.44 -1.8139 -0.9927 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O20 compound treatment 388220.0 -59200.0 -0.6 372170.0 -62700.0 -0.66 -0.8898 -0.999 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O21 compound treatment 380160.0 -67300.0 -0.68 406050.0 -28800.0 -0.3 -0.6967 -0.9324 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O22 compound treatment 413820.0 -33600.0 -0.34 373800.0 -61100.0 -0.64 -0.6938 -0.9568 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O23 compound treatment 437640.0 -9790.0 -0.1 469450.0 34600.0 0.36 0.186 0.4948 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 O24 compound treatment 405670.0 -41800.0 -0.42 381800.0 -53100.0 -0.56 -0.6931 -0.9911 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P01 compound treatment 111960.0 -335000.0 -3.41 85210.0 -350000.0 -3.66 -5.0009 -0.9994 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P02 compound treatment 93920.0 -354000.0 -3.59 119770.0 -315000.0 -3.3 -4.8745 -0.9991 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P03 compound treatment 413620.0 -33800.0 -0.34 368810.0 -66000.0 -0.69 -0.7322 -0.9478 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P04 compound treatment 411640.0 -35800.0 -0.36 367170.0 -67700.0 -0.71 -0.7586 -0.9519 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P05 compound treatment 349280.0 -98100.0 -1.0 342320.0 -92500.0 -0.97 -1.3908 -0.9999 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P06 compound treatment 365050.0 -82400.0 -0.84 337820.0 -97000.0 -1.02 -1.3108 -0.9953 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P07 compound treatment 351930.0 -95500.0 -0.97 422460.0 -12400.0 -0.13 -0.778 -0.7946 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P08 compound treatment 241990.0 -205000.0 -2.09 274110.0 -161000.0 -1.68 -2.6671 -0.9943 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P09 compound treatment 459460.0 12000.0 0.12 371900.0 -63000.0 -0.66 -0.3799 -0.5664 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P10 compound treatment 274560.0 -173000.0 -1.76 314400.0 -120000.0 -1.26 -2.1345 -0.9868 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P11 mock treatment 355760.0 -91700.0 -0.93 380000.0 -54900.0 -0.57 -1.0651 -0.9731 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P12 mock treatment 401170.0 -46300.0 -0.47 417610.0 -17200.0 -0.18 -0.4601 -0.9137 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P13 compound treatment 422350.0 -25100.0 -0.25 402690.0 -32200.0 -0.34 -0.4185 -0.9905 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P14 compound treatment 367920.0 -79500.0 -0.81 391880.0 -43000.0 -0.45 -0.8897 -0.9619 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P15 compound treatment 413280.0 -34100.0 -0.35 414360.0 -20500.0 -0.21 -0.3972 -0.9734 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P16 compound treatment 344250.0 -103000.0 -1.05 355450.0 -79400.0 -0.83 -1.3296 -0.9934 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P17 compound treatment 343310.0 -104000.0 -1.06 373800.0 -61100.0 -0.64 -1.2005 -0.9709 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P18 compound treatment 348010.0 -99400.0 -1.01 331200.0 -104000.0 -1.09 -1.4823 -0.9993 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P19 compound treatment 460290.0 12900.0 0.13 449370.0 14500.0 0.15 0.2 0.9971 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P20 compound treatment 201220.0 -246000.0 -2.5 230240.0 -205000.0 -2.14 -3.2851 -0.997 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P21 compound treatment 334400.0 -113000.0 -1.15 339270.0 -95600.0 -1.0 -1.5203 -0.9977 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P22 compound treatment 354960.0 -92500.0 -0.94 343240.0 -91600.0 -0.96 -1.3431 -0.9999 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P23 compound treatment 401170.0 -46300.0 -0.47 427680.0 -7170.0 -0.08 -0.3855 -0.8098 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2098 P24 compound treatment 407560.0 -39900.0 -0.41 405660.0 -29200.0 -0.31 -0.5027 -0.9904 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A01 compound treatment 407550.0 -43000.0 -0.44 469840.0 14900.0 0.16 -0.1983 -0.4274 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A02 compound treatment 490030.0 39500.0 0.4 460050.0 5140.0 0.05 0.3218 0.7948 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A03 compound treatment 426790.0 -23700.0 -0.24 501920.0 47000.0 0.49 0.1776 0.3239 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A04 compound treatment 370270.0 -80300.0 -0.82 417620.0 -37300.0 -0.39 -0.8531 -0.9432 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A05 compound treatment 353050.0 -97500.0 -0.99 496680.0 41800.0 0.44 -0.3911 -0.3611 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A06 compound treatment 408840.0 -41700.0 -0.42 448320.0 -6590.0 -0.07 -0.3485 -0.8117 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A07 compound treatment 463200.0 12700.0 0.13 377400.0 -77500.0 -0.81 -0.4833 -0.5877 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A08 compound treatment 400520.0 -50000.0 -0.51 445680.0 -9230.0 -0.1 -0.4278 -0.8269 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A09 compound treatment 356910.0 -93600.0 -0.95 377630.0 -77300.0 -0.81 -1.2453 -0.9968 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A10 compound treatment 401380.0 -49200.0 -0.5 460960.0 6050.0 0.06 -0.3084 -0.6125 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A11 compound treatment 390520.0 -60000.0 -0.61 412730.0 -42200.0 -0.44 -0.7438 -0.9875 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A12 compound treatment 468230.0 17700.0 0.18 455960.0 1050.0 0.01 0.1349 0.7488 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A13 mock treatment 406340.0 -44200.0 -0.45 436020.0 -18900.0 -0.2 -0.4576 -0.9322 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A14 mock treatment 361980.0 -88600.0 -0.9 364130.0 -90800.0 -0.95 -1.3089 -0.9996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A15 compound treatment 438370.0 -12200.0 -0.12 466590.0 11700.0 0.12 -9.0E-4 -0.0053 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A16 compound treatment 460370.0 9830.0 0.1 419080.0 -35800.0 -0.38 -0.1948 -0.5014 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A17 compound treatment 476020.0 25500.0 0.26 362890.0 -92000.0 -0.96 -0.4987 -0.4995 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A18 compound treatment 400800.0 -49700.0 -0.51 386180.0 -68700.0 -0.72 -0.8666 -0.985 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A19 compound treatment 467380.0 16800.0 0.17 417930.0 -37000.0 -0.39 -0.153 -0.3611 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A20 compound treatment 417170.0 -33400.0 -0.34 377410.0 -77500.0 -0.81 -0.814 -0.925 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A21 compound treatment 436040.0 -14500.0 -0.15 420190.0 -34700.0 -0.36 -0.3614 -0.9208 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A22 compound treatment 441700.0 -8840.0 -0.09 443880.0 -11000.0 -0.12 -0.1452 -0.9922 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A23 compound treatment 431200.0 -19300.0 -0.2 447790.0 -7120.0 -0.07 -0.1917 -0.9121 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 A24 compound treatment 431360.0 -19200.0 -0.19 445850.0 -9060.0 -0.09 -0.2049 -0.9454 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B01 compound treatment 486050.0 35500.0 0.36 491150.0 36200.0 0.38 0.5237 0.9997 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B02 compound treatment 546100.0 95600.0 0.97 513390.0 58500.0 0.61 1.1199 0.9753 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B03 compound treatment 439200.0 -11300.0 -0.12 456800.0 1890.0 0.02 -0.0675 -0.5774 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B04 compound treatment 467450.0 16900.0 0.17 467570.0 12700.0 0.13 0.2153 0.9918 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B05 compound treatment 455910.0 5370.0 0.05 486080.0 31200.0 0.33 0.2695 0.8141 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B06 compound treatment 462930.0 12400.0 0.13 420900.0 -34000.0 -0.36 -0.1629 -0.4311 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B07 compound treatment 439880.0 -10700.0 -0.11 464160.0 9250.0 0.1 -0.0081 -0.0556 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B08 compound treatment 398530.0 -52000.0 -0.53 442160.0 -12800.0 -0.13 -0.4682 -0.8589 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B09 compound treatment 458590.0 8050.0 0.08 449180.0 -5730.0 -0.06 0.0154 0.1516 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B10 compound treatment 510840.0 60300.0 0.61 484160.0 29200.0 0.31 0.65 0.9487 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B11 compound treatment 480480.0 29900.0 0.3 503760.0 48800.0 0.51 0.5771 0.9692 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B12 compound treatment 464660.0 14100.0 0.14 470460.0 15500.0 0.16 0.2167 0.998 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B13 mock treatment 380250.0 -70300.0 -0.71 471840.0 16900.0 0.18 -0.3797 -0.5159 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B14 mock treatment 550050.0 99500.0 1.01 426460.0 -28500.0 -0.3 0.5043 0.4783 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B15 compound treatment 400090.0 -50400.0 -0.51 490940.0 36000.0 0.38 -0.0956 -0.1501 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B16 compound treatment 519810.0 69300.0 0.7 468670.0 13800.0 0.14 0.5997 0.8346 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B17 compound treatment 516530.0 66000.0 0.67 452480.0 -2430.0 -0.03 0.4562 0.6797 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B18 compound treatment 421840.0 -28700.0 -0.29 418830.0 -36100.0 -0.38 -0.4735 -0.9918 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B19 compound treatment 414520.0 -36000.0 -0.37 416400.0 -38500.0 -0.4 -0.5441 -0.9988 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B20 compound treatment 421990.0 -28500.0 -0.29 512240.0 57300.0 0.6 0.2196 0.3292 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B21 compound treatment 458330.0 7790.0 0.08 404010.0 -50900.0 -0.53 -0.3211 -0.5956 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B22 compound treatment 408680.0 -41900.0 -0.43 407200.0 -47700.0 -0.5 -0.6543 -0.9968 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B23 compound treatment 473520.0 23000.0 0.23 422090.0 -32800.0 -0.34 -0.078 -0.1877 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 B24 compound treatment 470260.0 19700.0 0.2 468530.0 13600.0 0.14 0.2426 0.9861 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C01 compound treatment 439040.0 -11500.0 -0.12 400530.0 -54400.0 -0.57 -0.4855 -0.8347 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C02 compound treatment 436510.0 -14000.0 -0.14 394970.0 -59900.0 -0.63 -0.5449 -0.8461 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C03 compound treatment 443240.0 -7300.0 -0.07 397090.0 -57800.0 -0.61 -0.4808 -0.7878 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C04 compound treatment 426410.0 -24100.0 -0.25 419040.0 -35900.0 -0.38 -0.4391 -0.9786 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C05 compound treatment 394720.0 -55800.0 -0.57 347560.0 -107000.0 -1.12 -1.1964 -0.9498 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C06 compound treatment 357350.0 -93200.0 -0.95 418150.0 -36800.0 -0.39 -0.942 -0.9214 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C07 compound treatment 399360.0 -51200.0 -0.52 365600.0 -89300.0 -0.94 -1.0294 -0.9616 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C08 compound treatment 412440.0 -38100.0 -0.39 309300.0 -146000.0 -1.53 -1.3526 -0.8593 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C09 compound treatment 438020.0 -12500.0 -0.13 424280.0 -30600.0 -0.32 -0.3169 -0.9179 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C10 compound treatment 410000.0 -40500.0 -0.41 360360.0 -94600.0 -0.99 -0.9918 -0.9244 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C11 mock treatment 474030.0 23500.0 0.24 445210.0 -9700.0 -0.1 0.0969 0.3735 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C12 mock treatment 391680.0 -58900.0 -0.6 371840.0 -83100.0 -0.87 -1.0384 -0.9832 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C13 compound treatment 512100.0 61600.0 0.63 470510.0 15600.0 0.16 0.5579 0.8628 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C14 compound treatment 322560.0 -128000.0 -1.3 393480.0 -61400.0 -0.64 -1.3747 -0.9474 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C15 mock treatment 344890.0 -106000.0 -1.07 378790.0 -76100.0 -0.8 -1.3231 -0.9893 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C16 mock treatment 434640.0 -15900.0 -0.16 436680.0 -18200.0 -0.19 -0.2493 -0.9965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C17 compound treatment 418080.0 -32500.0 -0.33 409120.0 -45800.0 -0.48 -0.5725 -0.9833 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C18 compound treatment 423360.0 -27200.0 -0.28 425080.0 -29800.0 -0.31 -0.4163 -0.9981 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C19 compound treatment 416160.0 -34400.0 -0.35 380640.0 -74300.0 -0.78 -0.7973 -0.9347 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C20 compound treatment 385730.0 -64800.0 -0.66 346370.0 -109000.0 -1.14 -1.2699 -0.9663 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C21 compound treatment 393220.0 -57300.0 -0.58 364930.0 -90000.0 -0.94 -1.0785 -0.9732 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C22 compound treatment 393090.0 -57400.0 -0.58 411960.0 -43000.0 -0.45 -0.731 -0.9917 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C23 compound treatment 344550.0 -106000.0 -1.08 383160.0 -71800.0 -0.75 -1.2932 -0.9846 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 C24 compound treatment 378240.0 -72300.0 -0.73 416750.0 -38200.0 -0.4 -0.8022 -0.9591 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D01 compound treatment 430720.0 -19800.0 -0.2 428010.0 -26900.0 -0.28 -0.3417 -0.9864 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D02 compound treatment 440480.0 -10100.0 -0.1 385440.0 -69500.0 -0.73 -0.587 -0.7985 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D03 compound treatment 421120.0 -29400.0 -0.3 460880.0 5970.0 0.06 -0.1672 -0.5474 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D04 compound treatment 385630.0 -64900.0 -0.66 418370.0 -36500.0 -0.38 -0.7371 -0.9665 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D05 compound treatment 459960.0 9420.0 0.1 359360.0 -95600.0 -1.0 -0.6402 -0.6366 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D06 compound treatment 333020.0 -118000.0 -1.19 364640.0 -90300.0 -0.95 -1.5133 -0.9933 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D07 compound treatment 474080.0 23500.0 0.24 518580.0 63700.0 0.67 0.6409 0.9043 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D08 compound treatment 415050.0 -35500.0 -0.36 494280.0 39400.0 0.41 0.0367 0.0669 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D09 compound treatment 461370.0 10800.0 0.11 474510.0 19600.0 0.21 0.223 0.9573 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D10 compound treatment 388400.0 -62100.0 -0.63 413120.0 -41800.0 -0.44 -0.7561 -0.984 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D11 mock treatment 451140.0 605.0 0.01 504980.0 50100.0 0.52 0.3753 0.7153 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D12 mock treatment 475680.0 25100.0 0.26 419090.0 -35800.0 -0.38 -0.0847 -0.1866 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D13 compound treatment 451110.0 575.0 0.01 476320.0 21400.0 0.22 0.1627 0.7253 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D14 compound treatment 501830.0 51300.0 0.52 534300.0 79400.0 0.83 0.9567 0.9747 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D15 mock treatment 494320.0 43800.0 0.44 507840.0 52900.0 0.55 0.7067 0.994 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D16 mock treatment 382400.0 -68100.0 -0.69 479840.0 24900.0 0.26 -0.3049 -0.4121 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D17 compound treatment 428530.0 -22000.0 -0.22 418210.0 -36700.0 -0.38 -0.4301 -0.9667 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D18 compound treatment 471270.0 20700.0 0.21 419330.0 -35600.0 -0.37 -0.1146 -0.2677 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D19 compound treatment 389680.0 -60900.0 -0.62 466580.0 11700.0 0.12 -0.3509 -0.5566 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D20 compound treatment 336740.0 -114000.0 -1.16 436450.0 -18500.0 -0.19 -0.9545 -0.8141 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D21 compound treatment 404800.0 -45700.0 -0.46 443000.0 -11900.0 -0.12 -0.4169 -0.8663 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D22 compound treatment 449320.0 -1220.0 -0.01 442580.0 -12300.0 -0.13 -0.1001 -0.7712 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D23 compound treatment 462880.0 12300.0 0.13 460840.0 5930.0 0.06 0.1326 0.9474 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 D24 compound treatment 404800.0 -45700.0 -0.46 436520.0 -18400.0 -0.19 -0.4649 -0.924 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E01 mock treatment 479840.0 29300.0 0.3 450590.0 -4320.0 -0.05 0.1785 0.5927 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E02 mock treatment 411200.0 -39300.0 -0.4 491260.0 36300.0 0.38 -0.0134 -0.0242 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E03 compound treatment 480750.0 30200.0 0.31 533130.0 78200.0 0.82 0.7966 0.9102 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E04 compound treatment 425500.0 -25000.0 -0.25 432430.0 -22500.0 -0.24 -0.3465 -0.9993 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E05 compound treatment 434080.0 -16500.0 -0.17 404990.0 -49900.0 -0.52 -0.4881 -0.8888 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E06 compound treatment 421330.0 -29200.0 -0.3 357980.0 -96900.0 -1.02 -0.928 -0.8771 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E07 compound treatment 438830.0 -11700.0 -0.12 441920.0 -13000.0 -0.14 -0.1804 -0.9977 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E08 compound treatment 385960.0 -64600.0 -0.66 446930.0 -7980.0 -0.08 -0.5232 -0.7909 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E09 mock treatment 456250.0 5710.0 0.06 507490.0 52600.0 0.55 0.4306 0.7773 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E10 mock treatment 515200.0 64700.0 0.66 450810.0 -4100.0 -0.04 0.4342 0.6594 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E11 compound treatment 501630.0 51100.0 0.52 510300.0 55400.0 0.58 0.7775 0.9985 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E12 compound treatment 409570.0 -41000.0 -0.42 410690.0 -44200.0 -0.46 -0.622 -0.9986 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E13 compound treatment 457370.0 6830.0 0.07 512060.0 57100.0 0.6 0.4725 0.7839 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E14 compound treatment 470110.0 19600.0 0.2 401970.0 -52900.0 -0.55 -0.2516 -0.4269 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E15 compound treatment 506570.0 56000.0 0.57 468480.0 13600.0 0.14 0.5031 0.8573 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E16 compound treatment 400520.0 -50000.0 -0.51 470100.0 15200.0 0.16 -0.2469 -0.4636 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E17 mock treatment 476530.0 26000.0 0.26 481890.0 27000.0 0.28 0.3866 0.9994 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E18 mock treatment 445130.0 -5410.0 -0.05 452000.0 -2910.0 -0.03 -0.0604 -0.9616 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E19 compound treatment 436380.0 -14200.0 -0.14 430720.0 -24200.0 -0.25 -0.281 -0.964 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E20 compound treatment 434410.0 -16100.0 -0.16 410580.0 -44300.0 -0.46 -0.4443 -0.9021 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E21 compound treatment 391760.0 -58800.0 -0.6 428180.0 -26700.0 -0.28 -0.6204 -0.9404 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E22 compound treatment 469460.0 18900.0 0.19 380740.0 -74200.0 -0.78 -0.4136 -0.5166 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E23 compound treatment 368160.0 -82400.0 -0.84 414620.0 -40300.0 -0.42 -0.8905 -0.9498 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 E24 compound treatment 444960.0 -5580.0 -0.06 444120.0 -10800.0 -0.11 -0.12 -0.9489 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F01 mock treatment 438440.0 -12100.0 -0.12 442410.0 -12500.0 -0.13 -0.1796 -0.9995 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F02 mock treatment 442510.0 -8030.0 -0.08 448980.0 -5930.0 -0.06 -0.1016 -0.991 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F03 compound treatment 504070.0 53500.0 0.54 383160.0 -71800.0 -0.75 -0.1469 -0.1583 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F04 compound treatment 350320.0 -100000.0 -1.02 424550.0 -30400.0 -0.32 -0.9451 -0.8858 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F05 compound treatment 353680.0 -96900.0 -0.98 406560.0 -48400.0 -0.51 -1.0542 -0.9523 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F06 compound treatment 371910.0 -78600.0 -0.8 464610.0 9700.0 0.1 -0.4931 -0.6123 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F07 compound treatment 407930.0 -42600.0 -0.43 496800.0 41900.0 0.44 0.0042 0.0068 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F08 compound treatment 473650.0 23100.0 0.23 485600.0 30700.0 0.32 0.3934 0.9881 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F09 mock treatment 376900.0 -73600.0 -0.75 454090.0 -825.0 -0.01 -0.5352 -0.7152 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F10 mock treatment 511840.0 61300.0 0.62 347090.0 -108000.0 -1.13 -0.3583 -0.2777 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F11 compound treatment 483010.0 32500.0 0.33 522640.0 67700.0 0.71 0.7351 0.9393 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F12 compound treatment 405440.0 -45100.0 -0.46 455080.0 165.0 0.0 -0.3228 -0.7044 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F13 compound treatment 548410.0 97900.0 0.99 497680.0 42800.0 0.45 1.0201 0.9351 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F14 compound treatment 433880.0 -16700.0 -0.17 476700.0 21800.0 0.23 0.0417 0.1468 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F15 compound treatment 475650.0 25100.0 0.26 479680.0 24800.0 0.26 0.3639 1.0 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F16 compound treatment 381760.0 -68800.0 -0.7 487860.0 32900.0 0.35 -0.2501 -0.3209 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F17 mock treatment 402360.0 -48200.0 -0.49 487900.0 33000.0 0.35 -0.1018 -0.1699 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F18 mock treatment 493600.0 43100.0 0.44 460560.0 5650.0 0.06 0.3513 0.7954 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F19 compound treatment 416380.0 -34200.0 -0.35 474360.0 19400.0 0.2 -0.1014 -0.2519 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F20 compound treatment 423170.0 -27400.0 -0.28 467280.0 12400.0 0.13 -0.105 -0.3423 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F21 compound treatment 414370.0 -36200.0 -0.37 432640.0 -22300.0 -0.23 -0.4249 -0.976 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F22 compound treatment 399040.0 -51500.0 -0.52 458140.0 3230.0 0.03 -0.3461 -0.6601 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F23 compound treatment 432890.0 -17600.0 -0.18 388850.0 -66100.0 -0.69 -0.6163 -0.8618 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 F24 compound treatment 440510.0 -10000.0 -0.1 459290.0 4380.0 0.05 -0.0396 -0.3547 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G01 compound treatment 409790.0 -40700.0 -0.41 477470.0 22600.0 0.24 -0.1257 -0.2636 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G02 compound treatment 399400.0 -51100.0 -0.52 439010.0 -15900.0 -0.17 -0.4853 -0.8893 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G03 mock treatment 481780.0 31200.0 0.32 567280.0 112000.0 1.18 1.057 0.8668 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G04 mock treatment 393120.0 -57400.0 -0.58 404880.0 -50000.0 -0.52 -0.7833 -0.9986 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G05 compound treatment 474170.0 23600.0 0.24 364570.0 -90300.0 -0.95 -0.4995 -0.5115 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G06 compound treatment 421290.0 -29200.0 -0.3 494810.0 39900.0 0.42 0.0854 0.1666 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G07 compound treatment 419870.0 -30700.0 -0.31 467520.0 12600.0 0.13 -0.127 -0.3751 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G08 compound treatment 403360.0 -47200.0 -0.48 437810.0 -17100.0 -0.18 -0.4657 -0.9099 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G09 compound treatment 463370.0 12800.0 0.13 514110.0 59200.0 0.62 0.5308 0.8375 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G10 compound treatment 390250.0 -60300.0 -0.61 522110.0 67200.0 0.7 0.0646 0.0693 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G11 compound treatment 452320.0 1780.0 0.02 507450.0 52500.0 0.55 0.402 0.73 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G12 compound treatment 427430.0 -23100.0 -0.23 368290.0 -86600.0 -0.91 -0.8078 -0.8617 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G13 compound treatment 506890.0 56400.0 0.57 551860.0 96900.0 1.02 1.1232 0.9632 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G14 compound treatment 565640.0 115000.0 1.17 492590.0 37700.0 0.39 1.1062 0.8961 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G15 compound treatment 465840.0 15300.0 0.16 492230.0 37300.0 0.39 0.3864 0.9184 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G16 compound treatment 520640.0 70100.0 0.71 455860.0 945.0 0.01 0.5108 0.7169 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G17 compound treatment 497290.0 46800.0 0.48 428480.0 -26400.0 -0.28 0.1401 0.2548 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G18 compound treatment 503600.0 53100.0 0.54 490660.0 35700.0 0.37 0.6461 0.9841 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G19 mock treatment 470300.0 19800.0 0.2 496320.0 41400.0 0.43 0.4488 0.9388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G20 mock treatment 450360.0 -175.0 0.0 447130.0 -7780.0 -0.08 -0.0589 -0.7224 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G21 compound treatment 445320.0 -5220.0 -0.05 481560.0 26600.0 0.28 0.1599 0.5628 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G22 compound treatment 386970.0 -63600.0 -0.65 454260.0 -655.0 -0.01 -0.4616 -0.7146 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G23 compound treatment 420550.0 -30000.0 -0.3 474660.0 19700.0 0.21 -0.0692 -0.1878 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 G24 compound treatment 413410.0 -37100.0 -0.38 452330.0 -2580.0 -0.03 -0.2859 -0.7559 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H01 compound treatment 419210.0 -31300.0 -0.32 385340.0 -69600.0 -0.73 -0.7406 -0.931 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H02 compound treatment 468890.0 18400.0 0.19 395920.0 -59000.0 -0.62 -0.3052 -0.4727 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H03 mock treatment 412490.0 -38000.0 -0.39 417760.0 -37200.0 -0.39 -0.5487 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H04 mock treatment 398330.0 -52200.0 -0.53 449130.0 -5780.0 -0.06 -0.418 -0.7828 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H05 compound treatment 413320.0 -37200.0 -0.38 340860.0 -114000.0 -1.2 -1.1124 -0.8875 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H06 compound treatment 414320.0 -36200.0 -0.37 411630.0 -43300.0 -0.45 -0.5809 -0.9946 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H07 compound treatment 525470.0 74900.0 0.76 478340.0 23400.0 0.25 0.712 0.8899 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H08 compound treatment 374200.0 -76300.0 -0.78 429140.0 -25800.0 -0.27 -0.7395 -0.9003 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H09 compound treatment 405450.0 -45100.0 -0.46 478880.0 24000.0 0.25 -0.1464 -0.2802 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H10 compound treatment 420650.0 -29900.0 -0.3 518400.0 63500.0 0.67 0.2556 0.3495 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H11 compound treatment 324680.0 -126000.0 -1.28 347840.0 -107000.0 -1.12 -1.6976 -0.9979 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H12 compound treatment 456000.0 5460.0 0.06 481780.0 26900.0 0.28 0.2383 0.8306 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H13 compound treatment 427590.0 -22900.0 -0.23 490570.0 35700.0 0.37 0.0993 0.2254 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H14 compound treatment 424160.0 -26400.0 -0.27 527850.0 72900.0 0.76 0.3508 0.4332 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H15 compound treatment 485300.0 34800.0 0.35 453980.0 -935.0 -0.01 0.2429 0.6872 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H16 compound treatment 487540.0 37000.0 0.38 457680.0 2770.0 0.03 0.2864 0.7593 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H17 compound treatment 478770.0 28200.0 0.29 466370.0 11500.0 0.12 0.2878 0.9252 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H18 compound treatment 514020.0 63500.0 0.65 513560.0 58600.0 0.61 0.8907 0.9997 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H19 mock treatment 485780.0 35200.0 0.36 468180.0 13300.0 0.14 0.3515 0.915 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H20 mock treatment 423890.0 -26600.0 -0.27 478600.0 23700.0 0.25 -0.016 -0.0435 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H21 compound treatment 480160.0 29600.0 0.3 497120.0 42200.0 0.44 0.5256 0.9824 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H22 compound treatment 435880.0 -14700.0 -0.15 454100.0 -815.0 -0.01 -0.1113 -0.7464 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H23 compound treatment 375740.0 -74800.0 -0.76 404360.0 -50600.0 -0.53 -0.912 -0.9844 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 H24 compound treatment 414010.0 -36500.0 -0.37 433050.0 -21900.0 -0.23 -0.4245 -0.9731 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I01 compound treatment 469790.0 19300.0 0.2 526600.0 71700.0 0.75 0.6695 0.8625 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I02 compound treatment 369650.0 -80900.0 -0.82 373400.0 -81500.0 -0.85 -1.1851 -0.9998 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I03 compound treatment 334990.0 -116000.0 -1.17 399430.0 -55500.0 -0.58 -1.2413 -0.9474 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I04 compound treatment 440800.0 -9740.0 -0.1 305600.0 -149000.0 -1.56 -1.1762 -0.7503 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I05 mock treatment 390320.0 -60200.0 -0.61 463440.0 8530.0 0.09 -0.3695 -0.5976 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I06 mock treatment 460720.0 10200.0 0.1 487950.0 33000.0 0.35 0.3179 0.88 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I07 compound treatment 408480.0 -42100.0 -0.43 481290.0 26400.0 0.28 -0.1068 -0.2098 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I08 compound treatment 452000.0 1460.0 0.01 509780.0 54900.0 0.57 0.417 0.7252 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I09 compound treatment 445600.0 -4940.0 -0.05 505890.0 51000.0 0.53 0.3422 0.6379 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I10 compound treatment 520550.0 70000.0 0.71 424110.0 -30800.0 -0.32 0.2749 0.3518 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I11 compound treatment 482980.0 32400.0 0.33 549970.0 95100.0 1.0 0.9374 0.8935 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I12 compound treatment 440110.0 -10400.0 -0.11 483200.0 28300.0 0.3 0.1346 0.4278 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I13 compound treatment 540440.0 89900.0 0.91 487040.0 32100.0 0.34 0.884 0.908 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I14 compound treatment 443960.0 -6580.0 -0.07 487850.0 32900.0 0.35 0.1968 0.5598 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I15 compound treatment 543280.0 92700.0 0.94 566680.0 112000.0 1.17 1.4945 0.9942 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I16 compound treatment 480530.0 30000.0 0.3 534920.0 80000.0 0.84 0.8083 0.9062 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I17 compound treatment 429350.0 -21200.0 -0.22 464660.0 9750.0 0.1 -0.08 -0.3359 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I18 compound treatment 500070.0 49500.0 0.5 483160.0 28200.0 0.3 0.5652 0.9679 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I19 compound treatment 477540.0 27000.0 0.27 469180.0 14300.0 0.15 0.2997 0.9592 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I20 compound treatment 402330.0 -48200.0 -0.49 417980.0 -36900.0 -0.39 -0.62 -0.9932 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I21 mock treatment 481150.0 30600.0 0.31 409760.0 -45200.0 -0.47 -0.1146 -0.2023 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I22 mock treatment 470600.0 20100.0 0.2 467290.0 12400.0 0.13 0.2359 0.9761 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I23 compound treatment 434780.0 -15800.0 -0.16 455260.0 345.0 0.0 -0.1107 -0.691 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 I24 compound treatment 461530.0 11000.0 0.11 429670.0 -25200.0 -0.26 -0.108 -0.3762 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J01 compound treatment 437730.0 -12800.0 -0.13 415220.0 -39700.0 -0.42 -0.3861 -0.886 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J02 compound treatment 397290.0 -53200.0 -0.54 423640.0 -31300.0 -0.33 -0.6143 -0.9711 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J03 compound treatment 394790.0 -55700.0 -0.57 445870.0 -9040.0 -0.09 -0.4676 -0.8141 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J04 compound treatment 478850.0 28300.0 0.29 433230.0 -21700.0 -0.23 0.0428 0.1167 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J05 mock treatment 344400.0 -106000.0 -1.08 322400.0 -133000.0 -1.39 -1.7444 -0.9922 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J06 mock treatment 502570.0 52000.0 0.53 341560.0 -113000.0 -1.19 -0.4659 -0.3584 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J07 compound treatment 524250.0 73700.0 0.75 486400.0 31500.0 0.33 0.763 0.9321 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J08 compound treatment 370630.0 -79900.0 -0.81 391330.0 -63600.0 -0.67 -1.0453 -0.9952 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J09 compound treatment 496180.0 45600.0 0.46 486600.0 31700.0 0.33 0.5627 0.9865 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J10 compound treatment 432480.0 -18100.0 -0.18 451000.0 -3910.0 -0.04 -0.1587 -0.8443 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J11 compound treatment 435940.0 -14600.0 -0.15 383520.0 -71400.0 -0.75 -0.6338 -0.8311 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J12 compound treatment 395770.0 -54800.0 -0.56 377410.0 -77500.0 -0.81 -0.9677 -0.983 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J13 compound treatment 455730.0 5190.0 0.05 445890.0 -9020.0 -0.09 -0.0295 -0.2727 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J14 compound treatment 532380.0 81800.0 0.83 505510.0 50600.0 0.53 0.963 0.9763 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J15 compound treatment 472650.0 22100.0 0.22 489440.0 34500.0 0.36 0.4147 0.9738 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J16 compound treatment 462050.0 11500.0 0.12 453470.0 -1440.0 -0.02 0.072 0.6105 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J17 compound treatment 458880.0 8340.0 0.08 459540.0 4630.0 0.05 0.0942 0.9648 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J18 compound treatment 468040.0 17500.0 0.18 473930.0 19000.0 0.2 0.2667 0.9984 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J19 compound treatment 529210.0 78700.0 0.8 520770.0 65900.0 0.69 1.0532 0.9973 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J20 compound treatment 427240.0 -23300.0 -0.24 418640.0 -36300.0 -0.38 -0.4361 -0.974 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J21 mock treatment 493390.0 42900.0 0.44 467240.0 12300.0 0.13 0.3993 0.879 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J22 mock treatment 471010.0 20500.0 0.21 398720.0 -56200.0 -0.59 -0.2692 -0.4311 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J23 compound treatment 416420.0 -34100.0 -0.35 433820.0 -21100.0 -0.22 -0.4014 -0.9764 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 J24 compound treatment 402360.0 -48200.0 -0.49 400880.0 -54000.0 -0.57 -0.7465 -0.9974 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K01 compound treatment 454350.0 3810.0 0.04 543440.0 88500.0 0.93 0.6833 0.736 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K02 compound treatment 442370.0 -8170.0 -0.08 367610.0 -87300.0 -0.91 -0.7055 -0.7681 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K03 compound treatment 383040.0 -67500.0 -0.69 534840.0 79900.0 0.84 0.1071 0.099 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K04 compound treatment 360750.0 -89800.0 -0.91 457480.0 2570.0 0.03 -0.6262 -0.686 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K05 compound treatment 482950.0 32400.0 0.33 337020.0 -118000.0 -1.24 -0.6405 -0.501 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K06 compound treatment 315000.0 -136000.0 -1.38 333920.0 -121000.0 -1.27 -1.8703 -0.9991 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K07 mock treatment 486670.0 36100.0 0.37 339930.0 -115000.0 -1.2 -0.5922 -0.4702 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K08 mock treatment 501490.0 51000.0 0.52 430990.0 -23900.0 -0.25 0.1889 0.3283 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K09 compound treatment 471370.0 20800.0 0.21 399970.0 -54900.0 -0.58 -0.2574 -0.4196 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K10 compound treatment 331100.0 -119000.0 -1.21 464070.0 9160.0 0.1 -0.7904 -0.6492 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K11 compound treatment 493280.0 42700.0 0.43 433620.0 -21300.0 -0.22 0.1494 0.3059 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K12 compound treatment 448700.0 -1840.0 -0.02 446560.0 -8350.0 -0.09 -0.0751 -0.8389 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K13 compound treatment 532660.0 82100.0 0.83 558790.0 104000.0 1.09 1.3597 0.9914 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K14 compound treatment 468810.0 18300.0 0.19 421450.0 -33500.0 -0.35 -0.1166 -0.2939 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K15 mock treatment 476100.0 25600.0 0.26 521870.0 67000.0 0.7 0.6798 0.9087 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K16 mock treatment 475230.0 24700.0 0.25 531400.0 76500.0 0.8 0.7441 0.8861 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K17 compound treatment 567060.0 117000.0 1.18 577540.0 123000.0 1.28 1.7458 0.9992 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K18 compound treatment 566720.0 116000.0 1.18 429920.0 -25000.0 -0.26 0.6497 0.5372 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K19 compound treatment 442770.0 -7770.0 -0.08 504920.0 50000.0 0.52 0.3147 0.5939 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K20 compound treatment 488480.0 37900.0 0.39 477840.0 22900.0 0.24 0.4425 0.9741 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K21 compound treatment 488180.0 37600.0 0.38 500960.0 46000.0 0.48 0.6116 0.9934 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K22 compound treatment 524350.0 73800.0 0.75 485920.0 31000.0 0.32 0.7601 0.9299 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K23 mock treatment 485400.0 34900.0 0.35 401540.0 -53400.0 -0.56 -0.1449 -0.2189 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 K24 mock treatment 434240.0 -16300.0 -0.17 466000.0 11100.0 0.12 -0.035 -0.1729 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L01 compound treatment 392290.0 -58200.0 -0.59 516860.0 61900.0 0.65 0.0404 0.046 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L02 compound treatment 504020.0 53500.0 0.54 445150.0 -9760.0 -0.1 0.312 0.5641 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L03 compound treatment 420100.0 -30400.0 -0.31 498260.0 43300.0 0.45 0.1024 0.1864 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L04 compound treatment 416210.0 -34300.0 -0.35 365870.0 -89000.0 -0.93 -0.9064 -0.91 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L05 compound treatment 359950.0 -90600.0 -0.92 378650.0 -76300.0 -0.8 -1.2159 -0.9975 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L06 compound treatment 486170.0 35600.0 0.36 385620.0 -69300.0 -0.73 -0.2573 -0.3172 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L07 mock treatment 414930.0 -35600.0 -0.36 387490.0 -67400.0 -0.71 -0.7554 -0.9517 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L08 mock treatment 504680.0 54100.0 0.55 472520.0 17600.0 0.18 0.5195 0.8952 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L09 compound treatment 446520.0 -4020.0 -0.04 512900.0 58000.0 0.61 0.4007 0.6581 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L10 compound treatment 432720.0 -17800.0 -0.18 451740.0 -3170.0 -0.03 -0.1515 -0.8232 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L11 compound treatment 409980.0 -40600.0 -0.41 518740.0 63800.0 0.67 0.1814 0.231 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L12 compound treatment 473770.0 23200.0 0.24 518750.0 63800.0 0.67 0.6399 0.9022 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L13 compound treatment 422960.0 -27600.0 -0.28 450560.0 -4350.0 -0.05 -0.2304 -0.8116 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L14 compound treatment 529460.0 78900.0 0.8 553690.0 98800.0 1.03 1.2989 0.9921 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L15 mock treatment 515400.0 64900.0 0.66 574110.0 119000.0 1.25 1.3492 0.9554 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L16 mock treatment 486760.0 36200.0 0.37 520760.0 65800.0 0.69 0.7481 0.9567 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L17 compound treatment 488160.0 37600.0 0.38 471850.0 16900.0 0.18 0.3958 0.9391 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L18 compound treatment 459010.0 8470.0 0.09 465460.0 10500.0 0.11 0.139 0.9924 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L19 compound treatment 491400.0 40900.0 0.42 493450.0 38500.0 0.4 0.5791 0.9999 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L20 compound treatment 477980.0 27400.0 0.28 467090.0 12200.0 0.13 0.2874 0.9372 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L21 compound treatment 435210.0 -15300.0 -0.16 497310.0 42400.0 0.44 0.204 0.4333 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L22 compound treatment 383880.0 -66700.0 -0.68 427270.0 -27600.0 -0.29 -0.6838 -0.9282 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L23 mock treatment 462720.0 12200.0 0.12 468390.0 13500.0 0.14 0.1874 0.9979 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 L24 mock treatment 490800.0 40300.0 0.41 474600.0 19700.0 0.21 0.4352 0.9497 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M01 compound treatment 387680.0 -62900.0 -0.64 472550.0 17600.0 0.18 -0.321 -0.4828 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M02 compound treatment 452480.0 1940.0 0.02 499780.0 44900.0 0.47 0.3464 0.7362 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M03 compound treatment 475720.0 25200.0 0.26 443620.0 -11300.0 -0.12 0.0973 0.345 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M04 compound treatment 404570.0 -46000.0 -0.47 471530.0 16600.0 0.17 -0.2072 -0.4156 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M05 compound treatment 395400.0 -55100.0 -0.56 420160.0 -34800.0 -0.36 -0.6537 -0.9782 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M06 compound treatment 437370.0 -13200.0 -0.13 412360.0 -42600.0 -0.45 -0.4099 -0.8805 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M07 compound treatment 465050.0 14500.0 0.15 400510.0 -54400.0 -0.57 -0.2988 -0.5074 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M08 compound treatment 424490.0 -26000.0 -0.26 421320.0 -33600.0 -0.35 -0.436 -0.9901 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M09 mock treatment 405710.0 -44800.0 -0.46 472540.0 17600.0 0.18 -0.1915 -0.3896 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M10 mock treatment 533500.0 83000.0 0.84 497000.0 42100.0 0.44 0.908 0.9543 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M11 compound treatment 387170.0 -63400.0 -0.64 527200.0 72300.0 0.76 0.0802 0.0807 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M12 compound treatment 468930.0 18400.0 0.19 494970.0 40100.0 0.42 0.4289 0.9336 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M13 mock treatment 412800.0 -37700.0 -0.38 481780.0 26900.0 0.28 -0.0721 -0.1516 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M14 mock treatment 514370.0 63800.0 0.65 460240.0 5330.0 0.06 0.4981 0.7651 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M15 compound treatment 553980.0 103000.0 1.05 515200.0 60300.0 0.63 1.19 0.9703 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M16 compound treatment 498330.0 47800.0 0.49 551040.0 96100.0 1.01 1.0556 0.9441 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M17 compound treatment 497440.0 46900.0 0.48 540920.0 86000.0 0.9 0.9742 0.9557 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M18 compound treatment 526770.0 76200.0 0.77 509720.0 54800.0 0.57 0.9538 0.9891 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M19 compound treatment 488850.0 38300.0 0.39 447650.0 -7260.0 -0.08 0.2215 0.5583 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M20 compound treatment 462270.0 11700.0 0.12 508120.0 53200.0 0.56 0.4785 0.8394 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M21 compound treatment 459890.0 9350.0 0.1 513460.0 58500.0 0.61 0.501 0.8071 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M22 compound treatment 494630.0 44100.0 0.45 501450.0 46500.0 0.49 0.6616 0.9991 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M23 compound treatment 447870.0 -2670.0 -0.03 429780.0 -25100.0 -0.26 -0.2054 -0.7757 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 M24 compound treatment 464690.0 14200.0 0.14 475360.0 20400.0 0.21 0.2532 0.9812 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N01 compound treatment 422520.0 -28000.0 -0.28 395650.0 -59300.0 -0.62 -0.6404 -0.9375 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N02 compound treatment 432960.0 -17600.0 -0.18 468100.0 13200.0 0.14 -0.0286 -0.1267 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N03 compound treatment 405640.0 -44900.0 -0.46 336450.0 -118000.0 -1.24 -1.2003 -0.9076 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N04 compound treatment 390560.0 -60000.0 -0.61 450560.0 -4350.0 -0.05 -0.4632 -0.7579 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N05 compound treatment 399250.0 -51300.0 -0.52 435150.0 -19800.0 -0.21 -0.515 -0.9182 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N06 compound treatment 364590.0 -85900.0 -0.87 463040.0 8130.0 0.09 -0.5574 -0.6352 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N07 compound treatment 357140.0 -93400.0 -0.95 472080.0 17200.0 0.18 -0.5439 -0.5631 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N08 compound treatment 466790.0 16300.0 0.17 442820.0 -12100.0 -0.13 0.0272 0.1306 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N09 mock treatment 425120.0 -25400.0 -0.26 519940.0 65000.0 0.68 0.2991 0.4105 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N10 mock treatment 452840.0 2300.0 0.02 465180.0 10300.0 0.11 0.0926 0.8414 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N11 compound treatment 496010.0 45500.0 0.46 474640.0 19700.0 0.21 0.4729 0.9342 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N12 compound treatment 446690.0 -3850.0 -0.04 443940.0 -11000.0 -0.11 -0.1089 -0.897 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N13 mock treatment 398880.0 -51700.0 -0.52 477240.0 22300.0 0.23 -0.2058 -0.3581 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N14 mock treatment 493400.0 42900.0 0.44 457860.0 2950.0 0.03 0.3298 0.7553 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N15 compound treatment 487900.0 37400.0 0.38 503390.0 48500.0 0.51 0.6276 0.9897 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N16 compound treatment 528430.0 77900.0 0.79 517190.0 62300.0 0.65 1.0211 0.9954 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N17 compound treatment 438740.0 -11800.0 -0.12 417150.0 -37800.0 -0.4 -0.3645 -0.8817 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N18 compound treatment 507210.0 56700.0 0.58 453130.0 -1780.0 -0.02 0.394 0.6838 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N19 compound treatment 467010.0 16500.0 0.17 456060.0 1150.0 0.01 0.1269 0.7558 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N20 compound treatment 455460.0 4920.0 0.05 463320.0 8410.0 0.09 0.0977 0.9641 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N21 compound treatment 469770.0 19200.0 0.2 498450.0 43500.0 0.46 0.4608 0.9285 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N22 compound treatment 454600.0 4060.0 0.04 463580.0 8670.0 0.09 0.0934 0.9364 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N23 compound treatment 433800.0 -16700.0 -0.17 477550.0 22600.0 0.24 0.0474 0.1626 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 N24 compound treatment 450880.0 345.0 0.0 432080.0 -22800.0 -0.24 -0.1667 -0.6967 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O01 compound treatment 464110.0 13600.0 0.14 484290.0 29400.0 0.31 0.3152 0.9345 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O02 compound treatment 408520.0 -42000.0 -0.43 455840.0 925.0 0.01 -0.2951 -0.6909 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O03 compound treatment 445490.0 -5050.0 -0.05 462610.0 7700.0 0.08 0.0208 0.2172 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O04 compound treatment 412640.0 -37900.0 -0.39 443360.0 -11600.0 -0.12 -0.3579 -0.8866 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O05 compound treatment 398440.0 -52100.0 -0.53 447710.0 -7200.0 -0.08 -0.4277 -0.7998 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O06 compound treatment 428160.0 -22400.0 -0.23 446290.0 -8620.0 -0.09 -0.2247 -0.9183 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O07 compound treatment 500740.0 50200.0 0.51 469930.0 15000.0 0.16 0.472 0.8841 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O08 compound treatment 369380.0 -81200.0 -0.82 439320.0 -15600.0 -0.16 -0.6987 -0.831 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O09 compound treatment 410350.0 -40200.0 -0.41 512040.0 57100.0 0.6 0.1345 0.1856 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O10 compound treatment 400040.0 -50500.0 -0.51 427410.0 -27500.0 -0.29 -0.5666 -0.9628 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O11 mock treatment 478780.0 28200.0 0.29 445330.0 -9580.0 -0.1 0.1319 0.4339 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O12 mock treatment 458610.0 8070.0 0.08 491360.0 36400.0 0.38 0.328 0.8399 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O13 compound treatment 475610.0 25100.0 0.25 466750.0 11800.0 0.12 0.2679 0.9452 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O14 compound treatment 500230.0 49700.0 0.51 534840.0 79900.0 0.84 0.9492 0.9707 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O15 compound treatment 500890.0 50400.0 0.51 458880.0 3970.0 0.04 0.3912 0.762 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O16 compound treatment 492480.0 41900.0 0.43 474090.0 19200.0 0.2 0.4435 0.9411 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O17 compound treatment 452960.0 2420.0 0.02 415160.0 -39800.0 -0.42 -0.2771 -0.6641 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O18 compound treatment 456480.0 5940.0 0.06 462530.0 7620.0 0.08 0.0991 0.9906 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O19 compound treatment 441280.0 -9260.0 -0.09 481040.0 26100.0 0.27 0.127 0.4389 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O20 compound treatment 454090.0 3550.0 0.04 441340.0 -13600.0 -0.14 -0.075 -0.5113 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O21 compound treatment 448420.0 -2120.0 -0.02 453460.0 -1450.0 -0.02 -0.026 -0.9858 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O22 compound treatment 458530.0 7990.0 0.08 486210.0 31300.0 0.33 0.2893 0.8564 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O23 compound treatment 439730.0 -10800.0 -0.11 428000.0 -26900.0 -0.28 -0.277 -0.9155 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 O24 compound treatment 481840.0 31300.0 0.32 429560.0 -25400.0 -0.27 0.0371 0.0895 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P01 compound treatment 377350.0 -73200.0 -0.74 372610.0 -82300.0 -0.86 -1.1357 -0.9973 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P02 compound treatment 447890.0 -2650.0 -0.03 449120.0 -5790.0 -0.06 -0.0619 -0.9328 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P03 compound treatment 358470.0 -92100.0 -0.94 401140.0 -53800.0 -0.56 -1.06 -0.9705 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P04 compound treatment 373080.0 -77500.0 -0.79 437440.0 -17500.0 -0.18 -0.686 -0.8489 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P05 compound treatment 419590.0 -30900.0 -0.31 447100.0 -7810.0 -0.08 -0.2803 -0.8625 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P06 compound treatment 379100.0 -71400.0 -0.73 396110.0 -58800.0 -0.62 -0.949 -0.9967 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P07 compound treatment 463300.0 12800.0 0.13 467810.0 12900.0 0.14 0.1873 0.9998 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P08 compound treatment 404980.0 -45600.0 -0.46 360010.0 -94900.0 -0.99 -1.0305 -0.9395 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P09 compound treatment 421400.0 -29100.0 -0.3 404230.0 -50700.0 -0.53 -0.5849 -0.9619 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P10 compound treatment 364530.0 -86000.0 -0.87 395710.0 -59200.0 -0.62 -1.0566 -0.9859 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P11 mock treatment 401690.0 -48800.0 -0.5 384240.0 -70700.0 -0.74 -0.8746 -0.9811 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P12 mock treatment 396740.0 -53800.0 -0.55 434290.0 -20600.0 -0.22 -0.5394 -0.9175 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P13 compound treatment 432160.0 -18400.0 -0.19 388590.0 -66300.0 -0.69 -0.6234 -0.8664 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P14 compound treatment 465630.0 15100.0 0.15 478360.0 23400.0 0.25 0.2822 0.9743 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P15 compound treatment 439040.0 -11500.0 -0.12 405120.0 -49800.0 -0.52 -0.4515 -0.8445 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P16 compound treatment 424320.0 -26200.0 -0.27 428000.0 -26900.0 -0.28 -0.3878 -0.9996 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P17 compound treatment 438400.0 -12100.0 -0.12 405690.0 -49200.0 -0.52 -0.4519 -0.8522 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P18 compound treatment 437520.0 -13000.0 -0.13 429200.0 -25700.0 -0.27 -0.284 -0.9464 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P19 compound treatment 384130.0 -66400.0 -0.67 399680.0 -55200.0 -0.58 -0.8864 -0.9971 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P20 compound treatment 385860.0 -64700.0 -0.66 394350.0 -60600.0 -0.63 -0.9134 -0.9998 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P21 compound treatment 417440.0 -33100.0 -0.34 406760.0 -48200.0 -0.5 -0.5946 -0.9806 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P22 compound treatment 406890.0 -43600.0 -0.44 426260.0 -28700.0 -0.3 -0.5259 -0.9819 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P23 compound treatment 437600.0 -12900.0 -0.13 423200.0 -31700.0 -0.33 -0.3279 -0.9176 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2100 P24 compound treatment 402990.0 -47500.0 -0.48 398450.0 -56500.0 -0.59 -0.76 -0.9949 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A01 compound treatment 422010.0 -21500.0 -0.22 342880.0 -53500.0 -0.56 -0.5505 -0.9155 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A02 compound treatment 332980.0 -111000.0 -1.12 421160.0 24800.0 0.26 -0.6103 -0.5295 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A03 compound treatment 413470.0 -30000.0 -0.31 371570.0 -24800.0 -0.26 -0.3993 -0.9968 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A04 compound treatment 412810.0 -30700.0 -0.31 373710.0 -22600.0 -0.24 -0.3882 -0.9909 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A05 compound treatment 391690.0 -51800.0 -0.53 352180.0 -44200.0 -0.46 -0.6995 -0.9979 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A06 compound treatment 319040.0 -124000.0 -1.26 385560.0 -10800.0 -0.11 -0.9742 -0.7673 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A07 compound treatment 416590.0 -26900.0 -0.27 339600.0 -56800.0 -0.59 -0.6138 -0.9378 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A08 compound treatment 391810.0 -51700.0 -0.53 322010.0 -74300.0 -0.78 -0.9221 -0.9816 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A09 compound treatment 412240.0 -31200.0 -0.32 331680.0 -64700.0 -0.68 -0.7037 -0.9403 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A10 compound treatment 369610.0 -73900.0 -0.75 401390.0 5030.0 0.05 -0.4936 -0.6558 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A11 compound treatment 408840.0 -34600.0 -0.35 312960.0 -83400.0 -0.87 -0.8668 -0.9201 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A12 compound treatment 422880.0 -20600.0 -0.21 337340.0 -59000.0 -0.62 -0.5853 -0.8965 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A13 mock treatment 389730.0 -53800.0 -0.55 414270.0 17900.0 0.19 -0.2536 -0.439 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A14 mock treatment 392290.0 -51200.0 -0.52 408260.0 11900.0 0.12 -0.2797 -0.5228 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A15 compound treatment 367360.0 -76100.0 -0.77 357090.0 -39300.0 -0.41 -0.8379 -0.9563 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A16 compound treatment 325600.0 -118000.0 -1.2 395100.0 -1260.0 -0.01 -0.8564 -0.7148 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A17 compound treatment 389760.0 -53700.0 -0.55 370410.0 -25900.0 -0.27 -0.5783 -0.9482 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A18 compound treatment 397140.0 -46300.0 -0.47 337440.0 -58900.0 -0.62 -0.7695 -0.9911 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A19 compound treatment 394010.0 -49500.0 -0.5 392100.0 -4260.0 -0.04 -0.3871 -0.7668 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A20 compound treatment 391040.0 -52400.0 -0.53 397480.0 1120.0 0.01 -0.3685 -0.6913 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A21 compound treatment 373540.0 -69900.0 -0.71 408280.0 11900.0 0.12 -0.4143 -0.574 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A22 compound treatment 356320.0 -87200.0 -0.89 403680.0 7320.0 0.08 -0.5721 -0.6435 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A23 compound treatment 449340.0 5860.0 0.06 364570.0 -31800.0 -0.33 -0.1934 -0.5717 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 A24 compound treatment 403610.0 -39900.0 -0.41 402940.0 6580.0 0.07 -0.2378 -0.5784 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B01 compound treatment 437360.0 -6120.0 -0.06 434620.0 38300.0 0.4 0.2395 0.5903 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B02 compound treatment 442560.0 -924.0 -0.01 423480.0 27100.0 0.28 0.1943 0.6834 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B03 compound treatment 387310.0 -56200.0 -0.57 375910.0 -20400.0 -0.21 -0.5551 -0.9105 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B04 compound treatment 354880.0 -88600.0 -0.9 503520.0 107000.0 1.12 0.1573 0.1093 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B05 compound treatment 450560.0 7080.0 0.07 426250.0 29900.0 0.31 0.2723 0.8474 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B06 compound treatment 456020.0 12500.0 0.13 393920.0 -2440.0 -0.03 0.072 0.5543 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B07 compound treatment 466370.0 22900.0 0.23 384960.0 -11400.0 -0.12 0.08 0.306 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B08 compound treatment 408080.0 -35400.0 -0.36 440710.0 44400.0 0.46 0.0742 0.1262 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B09 compound treatment 479310.0 35800.0 0.36 408540.0 12200.0 0.13 0.3477 0.9012 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B10 compound treatment 397280.0 -46200.0 -0.47 394130.0 -2230.0 -0.02 -0.3485 -0.7413 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B11 compound treatment 431470.0 -12000.0 -0.12 447680.0 51300.0 0.54 0.2939 0.533 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B12 compound treatment 392720.0 -50800.0 -0.52 388120.0 -8240.0 -0.09 -0.4258 -0.8141 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B13 mock treatment 465280.0 21800.0 0.22 409320.0 13000.0 0.14 0.2526 0.9724 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B14 mock treatment 503920.0 60400.0 0.61 382500.0 -13900.0 -0.15 0.3316 0.5254 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B15 compound treatment 461760.0 18300.0 0.19 413330.0 17000.0 0.18 0.2571 0.9998 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B16 compound treatment 390080.0 -53400.0 -0.54 388260.0 -8100.0 -0.08 -0.4437 -0.8078 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B17 compound treatment 414680.0 -28800.0 -0.29 406940.0 10600.0 0.11 -0.1286 -0.4108 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B18 compound treatment 433880.0 -9600.0 -0.1 376160.0 -20200.0 -0.21 -0.2187 -0.9382 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B19 compound treatment 447710.0 4230.0 0.04 393170.0 -3190.0 -0.03 0.0067 0.124 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B20 compound treatment 441640.0 -1840.0 -0.02 398200.0 1840.0 0.02 4.0E-4 0.0147 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B21 compound treatment 418290.0 -25200.0 -0.26 424720.0 28400.0 0.3 0.0291 0.0742 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B22 compound treatment 475610.0 32100.0 0.33 448610.0 52300.0 0.55 0.618 0.9695 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B23 compound treatment 488840.0 45400.0 0.46 382530.0 -13800.0 -0.14 0.2235 0.4625 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 B24 compound treatment 431370.0 -12100.0 -0.12 387730.0 -8630.0 -0.09 -0.151 -0.9885 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C01 compound treatment 407590.0 -35900.0 -0.36 393850.0 -2510.0 -0.03 -0.2765 -0.7561 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C02 compound treatment 335470.0 -108000.0 -1.1 375750.0 -20600.0 -0.22 -0.9288 -0.8303 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C03 compound treatment 340730.0 -103000.0 -1.04 316800.0 -79600.0 -0.83 -1.3278 -0.9938 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C04 compound treatment 463460.0 20000.0 0.2 336360.0 -60000.0 -0.63 -0.301 -0.4556 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C05 compound treatment 441730.0 -1750.0 -0.02 348440.0 -47900.0 -0.5 -0.3676 -0.7318 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C06 compound treatment 332680.0 -111000.0 -1.13 364720.0 -31600.0 -0.33 -1.0306 -0.878 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C07 compound treatment 328840.0 -115000.0 -1.17 305990.0 -90400.0 -0.95 -1.4933 -0.9947 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C08 compound treatment 359060.0 -84400.0 -0.86 292850.0 -104000.0 -1.08 -1.3735 -0.9933 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C09 compound treatment 377070.0 -66400.0 -0.67 356750.0 -39600.0 -0.41 -0.7707 -0.9727 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C10 compound treatment 342530.0 -101000.0 -1.03 297860.0 -98500.0 -1.03 -1.4552 -1.0 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C11 mock treatment 301920.0 -142000.0 -1.44 340970.0 -55400.0 -0.58 -1.4276 -0.9203 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C12 mock treatment 458980.0 15500.0 0.16 350270.0 -46100.0 -0.48 -0.2301 -0.453 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C13 compound treatment 352220.0 -91300.0 -0.93 360910.0 -35400.0 -0.37 -0.9184 -0.9193 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C14 compound treatment 441770.0 -1710.0 -0.02 303310.0 -93000.0 -0.97 -0.7017 -0.7196 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C15 mock treatment 352610.0 -90900.0 -0.92 413780.0 17400.0 0.18 -0.5239 -0.5566 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C16 mock treatment 381060.0 -62400.0 -0.63 354750.0 -41600.0 -0.44 -0.7568 -0.9832 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C17 compound treatment 335120.0 -108000.0 -1.1 339930.0 -56400.0 -0.59 -1.1967 -0.9575 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C18 compound treatment 341080.0 -102000.0 -1.04 313680.0 -82700.0 -0.87 -1.3484 -0.9958 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C19 compound treatment 402920.0 -40600.0 -0.41 346480.0 -49900.0 -0.52 -0.661 -0.9931 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C20 compound treatment 369710.0 -73800.0 -0.75 331840.0 -64500.0 -0.68 -1.0081 -0.9987 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C21 compound treatment 353170.0 -90300.0 -0.92 338120.0 -58200.0 -0.61 -1.0804 -0.9803 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C22 compound treatment 390210.0 -53300.0 -0.54 361710.0 -34600.0 -0.36 -0.6395 -0.9811 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C23 compound treatment 379840.0 -63600.0 -0.65 340980.0 -55400.0 -0.58 -0.8676 -0.9985 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 C24 compound treatment 396290.0 -47200.0 -0.48 367920.0 -28400.0 -0.3 -0.5498 -0.9738 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D01 compound treatment 427890.0 -15600.0 -0.16 405380.0 9020.0 0.09 -0.0452 -0.245 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D02 compound treatment 482450.0 39000.0 0.4 411390.0 15000.0 0.16 0.3914 0.9184 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D03 compound treatment 470850.0 27400.0 0.28 343650.0 -52700.0 -0.55 -0.1939 -0.3135 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D04 compound treatment 472690.0 29200.0 0.3 417760.0 21400.0 0.22 0.3684 0.9904 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D05 compound treatment 424760.0 -18700.0 -0.19 441980.0 45600.0 0.48 0.2035 0.3955 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D06 compound treatment 340390.0 -103000.0 -1.05 372320.0 -24000.0 -0.25 -0.9189 -0.8528 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D07 compound treatment 384130.0 -59400.0 -0.6 385170.0 -11200.0 -0.12 -0.5094 -0.829 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D08 compound treatment 461340.0 17900.0 0.18 369780.0 -26600.0 -0.28 -0.0686 -0.2064 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D09 compound treatment 407230.0 -36300.0 -0.37 350810.0 -45500.0 -0.48 -0.598 -0.9918 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D10 compound treatment 391220.0 -52300.0 -0.53 448510.0 52200.0 0.55 0.0108 0.0142 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D11 mock treatment 431740.0 -11700.0 -0.12 388520.0 -7840.0 -0.08 -0.1425 -0.9834 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D12 mock treatment 498910.0 55400.0 0.56 402880.0 6520.0 0.07 0.4466 0.7871 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D13 compound treatment 431290.0 -12200.0 -0.12 368770.0 -27600.0 -0.29 -0.292 -0.9285 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D14 compound treatment 419320.0 -24200.0 -0.25 445930.0 49600.0 0.52 0.1936 0.337 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D15 mock treatment 463170.0 19700.0 0.2 365540.0 -30800.0 -0.32 -0.0869 -0.2287 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D16 mock treatment 377440.0 -66000.0 -0.67 418190.0 21800.0 0.23 -0.3128 -0.4412 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D17 compound treatment 394610.0 -48900.0 -0.5 425000.0 28600.0 0.3 -0.139 -0.2395 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D18 compound treatment 419070.0 -24400.0 -0.25 402140.0 5780.0 0.06 -0.1326 -0.5192 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D19 compound treatment 419940.0 -23500.0 -0.24 398140.0 1780.0 0.02 -0.156 -0.6499 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D20 compound treatment 484960.0 41500.0 0.42 371450.0 -24900.0 -0.26 0.1135 0.2289 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D21 compound treatment 398560.0 -44900.0 -0.46 376550.0 -19800.0 -0.21 -0.4696 -0.9363 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D22 compound treatment 479240.0 35800.0 0.36 392770.0 -3590.0 -0.04 0.2303 0.6306 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D23 compound treatment 405000.0 -38500.0 -0.39 363650.0 -32700.0 -0.34 -0.5189 -0.9978 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 D24 compound treatment 394200.0 -49300.0 -0.5 378080.0 -18300.0 -0.19 -0.4896 -0.913 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E01 mock treatment 383580.0 -59900.0 -0.61 359250.0 -37100.0 -0.39 -0.7054 -0.9765 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E02 mock treatment 409780.0 -33700.0 -0.34 419930.0 23600.0 0.25 -0.0675 -0.16 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E03 compound treatment 468110.0 24600.0 0.25 365180.0 -31200.0 -0.33 -0.054 -0.1313 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E04 compound treatment 425120.0 -18400.0 -0.19 363460.0 -32900.0 -0.34 -0.3757 -0.9585 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E05 compound treatment 452580.0 9100.0 0.09 334030.0 -62300.0 -0.65 -0.3964 -0.601 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E06 compound treatment 430730.0 -12800.0 -0.13 322970.0 -73400.0 -0.77 -0.6354 -0.8148 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E07 compound treatment 502080.0 58600.0 0.6 420030.0 23700.0 0.25 0.5964 0.9246 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E08 compound treatment 457340.0 13900.0 0.14 392830.0 -3530.0 -0.04 0.0734 0.5044 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E09 mock treatment 489780.0 46300.0 0.47 435000.0 38600.0 0.4 0.619 0.9972 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E10 mock treatment 450440.0 6960.0 0.07 420380.0 24000.0 0.25 0.228 0.872 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E11 compound treatment 421890.0 -21600.0 -0.22 394960.0 -1400.0 -0.01 -0.1655 -0.7526 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E12 compound treatment 464600.0 21100.0 0.21 372870.0 -23500.0 -0.25 -0.0223 -0.0683 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E13 compound treatment 453330.0 9850.0 0.1 396880.0 522.0 0.01 0.0746 0.7447 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E14 compound treatment 464170.0 20700.0 0.21 425390.0 29000.0 0.3 0.3637 0.9837 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E15 compound treatment 383370.0 -60100.0 -0.61 366430.0 -29900.0 -0.31 -0.6537 -0.952 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E16 compound treatment 391840.0 -51600.0 -0.52 363310.0 -33000.0 -0.35 -0.6159 -0.9796 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E17 mock treatment 405530.0 -38000.0 -0.39 396920.0 562.0 0.01 -0.2686 -0.6962 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E18 mock treatment 437290.0 -6190.0 -0.06 409440.0 13100.0 0.14 0.0524 0.3475 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E19 compound treatment 430080.0 -13400.0 -0.14 383140.0 -13200.0 -0.14 -0.1942 -1.0 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E20 compound treatment 427730.0 -15800.0 -0.16 356530.0 -39800.0 -0.42 -0.4083 -0.9135 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E21 compound treatment 356890.0 -86600.0 -0.88 297760.0 -98600.0 -1.03 -1.3527 -0.9968 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E22 compound treatment 383120.0 -60400.0 -0.61 375390.0 -21000.0 -0.22 -0.5891 -0.9041 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E23 compound treatment 365600.0 -77900.0 -0.79 356000.0 -40400.0 -0.42 -0.8587 -0.9569 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 E24 compound treatment 375120.0 -68400.0 -0.69 373130.0 -23200.0 -0.24 -0.6633 -0.9011 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F01 mock treatment 398250.0 -45200.0 -0.46 458580.0 62200.0 0.65 0.1359 0.1704 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F02 mock treatment 450880.0 7400.0 0.08 466350.0 70000.0 0.73 0.5717 0.7755 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F03 compound treatment 433440.0 -10000.0 -0.1 377130.0 -19200.0 -0.2 -0.2146 -0.9503 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F04 compound treatment 373810.0 -69700.0 -0.71 426280.0 29900.0 0.31 -0.279 -0.3603 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F05 compound treatment 437500.0 -5980.0 -0.06 427270.0 30900.0 0.32 0.186 0.5645 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F06 compound treatment 452960.0 9480.0 0.1 425240.0 28900.0 0.3 0.2821 0.8882 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F07 compound treatment 411200.0 -32300.0 -0.33 455890.0 59500.0 0.62 0.2091 0.2967 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F08 compound treatment 402280.0 -41200.0 -0.42 418830.0 22500.0 0.24 -0.1296 -0.2698 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F09 mock treatment 505550.0 62100.0 0.63 474990.0 78600.0 0.82 1.0285 0.9913 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F10 mock treatment 401040.0 -42400.0 -0.43 400610.0 4250.0 0.04 -0.2735 -0.6307 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F11 compound treatment 468080.0 24600.0 0.25 380010.0 -16300.0 -0.17 0.0556 0.1836 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F12 compound treatment 510020.0 66500.0 0.68 388010.0 -8350.0 -0.09 0.4163 0.6105 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F13 compound treatment 486500.0 43000.0 0.44 414530.0 18200.0 0.19 0.4437 0.9306 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F14 compound treatment 476960.0 33500.0 0.34 341600.0 -54800.0 -0.57 -0.1651 -0.2476 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F15 compound treatment 460810.0 17300.0 0.18 375740.0 -20600.0 -0.22 -0.0283 -0.1014 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F16 compound treatment 392200.0 -51300.0 -0.52 397500.0 1140.0 0.01 -0.3601 -0.6907 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F17 mock treatment 408330.0 -35200.0 -0.36 372160.0 -24200.0 -0.25 -0.4319 -0.9859 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F18 mock treatment 463690.0 20200.0 0.21 373090.0 -23300.0 -0.24 -0.0272 -0.0853 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F19 compound treatment 426440.0 -17000.0 -0.17 408010.0 11700.0 0.12 -0.0361 -0.1706 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F20 compound treatment 443640.0 156.0 0.0 417630.0 21300.0 0.22 0.1587 0.7121 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F21 compound treatment 430040.0 -13400.0 -0.14 386130.0 -10200.0 -0.11 -0.1724 -0.9928 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F22 compound treatment 448480.0 5000.0 0.05 358290.0 -38100.0 -0.4 -0.2461 -0.6122 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F23 compound treatment 422880.0 -20600.0 -0.21 417180.0 20800.0 0.22 0.0062 0.0205 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 F24 compound treatment 437890.0 -5590.0 -0.06 430080.0 33700.0 0.35 0.2096 0.5858 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G01 compound treatment 394890.0 -48600.0 -0.49 405320.0 8960.0 0.09 -0.2828 -0.5626 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G02 compound treatment 404880.0 -38600.0 -0.39 428960.0 32600.0 0.34 -0.0359 -0.0689 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G03 mock treatment 453690.0 10200.0 0.1 461310.0 65000.0 0.68 0.5545 0.8056 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G04 mock treatment 457990.0 14500.0 0.15 376770.0 -19600.0 -0.21 -0.0409 -0.1618 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G05 compound treatment 449970.0 6490.0 0.07 387410.0 -8950.0 -0.09 -0.0197 -0.1718 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G06 compound treatment 455520.0 12000.0 0.12 354560.0 -41800.0 -0.44 -0.2232 -0.4908 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G07 compound treatment 498030.0 54500.0 0.55 370320.0 -26000.0 -0.27 0.199 0.3222 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G08 compound treatment 366720.0 -76800.0 -0.78 388010.0 -8350.0 -0.09 -0.6135 -0.7815 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G09 compound treatment 469050.0 25600.0 0.26 391100.0 -5260.0 -0.06 0.1448 0.545 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G10 compound treatment 400440.0 -43000.0 -0.44 347570.0 -48800.0 -0.51 -0.6708 -0.997 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G11 compound treatment 465880.0 22400.0 0.23 353620.0 -42700.0 -0.45 -0.1557 -0.31 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G12 compound treatment 444000.0 516.0 0.01 355560.0 -40800.0 -0.43 -0.2986 -0.6984 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G13 compound treatment 342050.0 -101000.0 -1.03 387840.0 -8520.0 -0.09 -0.792 -0.7655 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G14 compound treatment 495110.0 51600.0 0.52 341790.0 -54600.0 -0.57 -0.0333 -0.0429 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G15 compound treatment 377050.0 -66400.0 -0.68 397360.0 1000.0 0.01 -0.47 -0.696 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G16 compound treatment 439850.0 -3630.0 -0.04 373530.0 -22800.0 -0.24 -0.1952 -0.8067 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G17 compound treatment 411940.0 -31500.0 -0.32 422340.0 26000.0 0.27 -0.0342 -0.0813 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G18 compound treatment 414440.0 -29000.0 -0.3 403420.0 7060.0 0.07 -0.1564 -0.5139 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G19 mock treatment 446960.0 3480.0 0.04 345370.0 -51000.0 -0.53 -0.3528 -0.6589 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G20 mock treatment 506270.0 62800.0 0.64 356570.0 -39800.0 -0.42 0.1564 0.2052 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G21 compound treatment 418880.0 -24600.0 -0.25 359850.0 -36500.0 -0.38 -0.4473 -0.9788 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G22 compound treatment 458100.0 14600.0 0.15 345860.0 -50500.0 -0.53 -0.2691 -0.4897 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G23 compound treatment 427780.0 -15700.0 -0.16 375090.0 -21300.0 -0.22 -0.2704 -0.9866 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 G24 compound treatment 397570.0 -45900.0 -0.47 399610.0 3250.0 0.03 -0.3058 -0.6537 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H01 compound treatment 445830.0 2350.0 0.02 355040.0 -41300.0 -0.43 -0.2893 -0.6672 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H02 compound treatment 394990.0 -48500.0 -0.49 473930.0 77600.0 0.81 0.2262 0.238 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H03 mock treatment 428850.0 -14600.0 -0.15 334260.0 -62100.0 -0.65 -0.5652 -0.8469 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H04 mock treatment 474480.0 31000.0 0.31 291970.0 -104000.0 -1.09 -0.5507 -0.4838 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H05 compound treatment 474140.0 30700.0 0.31 273210.0 -123000.0 -1.29 -0.6921 -0.5214 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H06 compound treatment 428850.0 -14600.0 -0.15 426240.0 29900.0 0.31 0.1162 0.3353 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H07 compound treatment 501380.0 57900.0 0.59 417870.0 21500.0 0.23 0.5754 0.9133 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H08 compound treatment 462750.0 19300.0 0.2 401200.0 4840.0 0.05 0.1743 0.8619 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H09 compound treatment 401280.0 -42200.0 -0.43 398960.0 2600.0 0.03 -0.284 -0.6608 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H10 compound treatment 457090.0 13600.0 0.14 427540.0 31200.0 0.33 0.3288 0.9268 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H11 compound treatment 419270.0 -24200.0 -0.25 423680.0 27300.0 0.29 0.0284 0.0753 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H12 compound treatment 347850.0 -95600.0 -0.97 378940.0 -17400.0 -0.18 -0.8162 -0.8255 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H13 compound treatment 377610.0 -65900.0 -0.67 418970.0 22600.0 0.24 -0.3058 -0.4307 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H14 compound treatment 472350.0 28900.0 0.29 410080.0 13700.0 0.14 0.3091 0.9461 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H15 compound treatment 460830.0 17300.0 0.18 435100.0 38700.0 0.41 0.4117 0.9302 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H16 compound treatment 524550.0 81100.0 0.82 417860.0 21500.0 0.23 0.7418 0.8686 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H17 compound treatment 506800.0 63300.0 0.64 364530.0 -31800.0 -0.33 0.2192 0.3024 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H18 compound treatment 408810.0 -34700.0 -0.35 406980.0 10600.0 0.11 -0.1705 -0.4613 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H19 mock treatment 415610.0 -27900.0 -0.28 461400.0 65000.0 0.68 0.2816 0.3815 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H20 mock treatment 453980.0 10500.0 0.11 401770.0 5410.0 0.06 0.1155 0.9563 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H21 compound treatment 413400.0 -30100.0 -0.31 406720.0 10400.0 0.11 -0.1394 -0.4297 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H22 compound treatment 402900.0 -40600.0 -0.41 377220.0 -19100.0 -0.2 -0.4334 -0.9451 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H23 compound treatment 343680.0 -99800.0 -1.01 386400.0 -9960.0 -0.1 -0.7909 -0.7758 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 H24 compound treatment 446670.0 3190.0 0.03 385660.0 -10700.0 -0.11 -0.0564 -0.4831 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I01 compound treatment 358600.0 -84900.0 -0.86 322100.0 -74300.0 -0.78 -1.1601 -0.9987 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I02 compound treatment 387270.0 -56200.0 -0.57 400680.0 4320.0 0.05 -0.3719 -0.649 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I03 compound treatment 373620.0 -69900.0 -0.71 324220.0 -72100.0 -0.76 -1.0365 -0.9995 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I04 compound treatment 444800.0 1320.0 0.01 382150.0 -14200.0 -0.15 -0.0958 -0.641 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I05 mock treatment 365990.0 -77500.0 -0.79 410760.0 14400.0 0.15 -0.4501 -0.5614 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I06 mock treatment 413920.0 -29600.0 -0.3 434890.0 38500.0 0.4 0.073 0.1451 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I07 compound treatment 388030.0 -55500.0 -0.56 390120.0 -6240.0 -0.07 -0.4447 -0.7839 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I08 compound treatment 361140.0 -82300.0 -0.84 378010.0 -18300.0 -0.19 -0.7276 -0.8475 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I09 compound treatment 365150.0 -78300.0 -0.8 397600.0 1240.0 0.01 -0.5537 -0.6955 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I10 compound treatment 392080.0 -51400.0 -0.52 369940.0 -26400.0 -0.28 -0.5651 -0.9559 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I11 compound treatment 310730.0 -133000.0 -1.35 372320.0 -24000.0 -0.25 -1.132 -0.8249 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I12 compound treatment 432250.0 -11200.0 -0.11 379320.0 -17000.0 -0.18 -0.207 -0.9767 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I13 compound treatment 459450.0 16000.0 0.16 435700.0 39300.0 0.41 0.4062 0.917 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I14 compound treatment 489920.0 46400.0 0.47 414620.0 18300.0 0.19 0.469 0.921 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I15 compound treatment 472370.0 28900.0 0.29 411920.0 15600.0 0.16 0.3229 0.9615 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I16 compound treatment 401840.0 -41600.0 -0.42 399840.0 3480.0 0.04 -0.2734 -0.6438 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I17 compound treatment 429840.0 -13600.0 -0.14 394720.0 -1640.0 -0.02 -0.1102 -0.7886 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I18 compound treatment 522080.0 78600.0 0.8 380860.0 -15500.0 -0.16 0.4499 0.5521 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I19 compound treatment 417250.0 -26200.0 -0.27 404190.0 7830.0 0.08 -0.1305 -0.4678 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I20 compound treatment 473390.0 29900.0 0.3 389980.0 -6380.0 -0.07 0.1676 0.5388 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I21 mock treatment 442150.0 -1330.0 -0.01 403570.0 7210.0 0.08 0.0438 0.5711 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I22 mock treatment 434930.0 -8550.0 -0.09 390250.0 -6110.0 -0.06 -0.1067 -0.9887 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I23 compound treatment 388240.0 -55200.0 -0.56 342820.0 -53500.0 -0.56 -0.7936 -1.0 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 I24 compound treatment 408750.0 -34700.0 -0.35 409190.0 12800.0 0.13 -0.1545 -0.4091 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J01 compound treatment 410830.0 -32700.0 -0.33 345490.0 -50900.0 -0.53 -0.6115 -0.974 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J02 compound treatment 444720.0 1240.0 0.01 381640.0 -14700.0 -0.15 -0.1002 -0.6474 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J03 compound treatment 414880.0 -28600.0 -0.29 433070.0 36700.0 0.38 0.0664 0.1378 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J04 compound treatment 398580.0 -44900.0 -0.46 298030.0 -98300.0 -1.03 -1.0512 -0.9329 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J05 mock treatment 372120.0 -71400.0 -0.73 337760.0 -58600.0 -0.61 -0.9469 -0.9966 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J06 mock treatment 506040.0 62600.0 0.64 391840.0 -4520.0 -0.05 0.416 0.6526 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J07 compound treatment 404180.0 -39300.0 -0.4 367840.0 -28500.0 -0.3 -0.4937 -0.9898 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J08 compound treatment 416080.0 -27400.0 -0.28 396160.0 -198.0 0.0 -0.1984 -0.7124 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J09 compound treatment 494030.0 50500.0 0.51 299380.0 -97000.0 -1.02 -0.3553 -0.312 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J10 compound treatment 420880.0 -22600.0 -0.23 341970.0 -54400.0 -0.57 -0.5654 -0.9202 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J11 compound treatment 407210.0 -36300.0 -0.37 312960.0 -83400.0 -0.87 -0.8785 -0.9264 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J12 compound treatment 477030.0 33500.0 0.34 317680.0 -78700.0 -0.82 -0.3419 -0.3832 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J13 compound treatment 415520.0 -28000.0 -0.28 394120.0 -2240.0 -0.02 -0.2175 -0.7629 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J14 compound treatment 431710.0 -11800.0 -0.12 380320.0 -16000.0 -0.17 -0.2034 -0.9861 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J15 compound treatment 439380.0 -4100.0 -0.04 411330.0 15000.0 0.16 0.0814 0.5017 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J16 compound treatment 411640.0 -31800.0 -0.32 349500.0 -46900.0 -0.49 -0.576 -0.9795 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J17 compound treatment 451950.0 8470.0 0.09 389440.0 -6920.0 -0.07 0.0096 0.0851 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J18 compound treatment 396430.0 -47100.0 -0.48 383680.0 -12700.0 -0.13 -0.432 -0.8706 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J19 compound treatment 403750.0 -39700.0 -0.4 437410.0 41100.0 0.43 0.0186 0.0316 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J20 compound treatment 451520.0 8040.0 0.08 347310.0 -49000.0 -0.51 -0.3056 -0.5874 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J21 mock treatment 423110.0 -20400.0 -0.21 372890.0 -23500.0 -0.25 -0.3203 -0.9963 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J22 mock treatment 402330.0 -41200.0 -0.42 381560.0 -14800.0 -0.16 -0.4054 -0.9088 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J23 compound treatment 424180.0 -19300.0 -0.2 355400.0 -41000.0 -0.43 -0.4422 -0.9371 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 J24 compound treatment 444320.0 836.0 0.01 370200.0 -26200.0 -0.27 -0.1878 -0.6849 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K01 compound treatment 433450.0 -10000.0 -0.1 344320.0 -52000.0 -0.55 -0.4576 -0.825 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K02 compound treatment 332800.0 -111000.0 -1.12 390680.0 -5680.0 -0.06 -0.8374 -0.7435 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K03 compound treatment 327790.0 -116000.0 -1.18 427730.0 31400.0 0.33 -0.5989 -0.4906 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K04 compound treatment 418960.0 -24500.0 -0.25 319150.0 -77200.0 -0.81 -0.7482 -0.884 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K05 compound treatment 410830.0 -32700.0 -0.33 340390.0 -56000.0 -0.59 -0.6493 -0.9637 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K06 compound treatment 505780.0 62300.0 0.63 340160.0 -56200.0 -0.59 0.0313 0.0362 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K07 mock treatment 396060.0 -47400.0 -0.48 430250.0 33900.0 0.36 -0.0897 -0.1498 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K08 mock treatment 445230.0 1750.0 0.02 385340.0 -11000.0 -0.12 -0.0691 -0.5915 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K09 compound treatment 430720.0 -12800.0 -0.13 393620.0 -2740.0 -0.03 -0.112 -0.8431 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K10 compound treatment 483120.0 39600.0 0.4 423150.0 26800.0 0.28 0.4833 0.9844 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K11 compound treatment 535940.0 92500.0 0.94 455200.0 58800.0 0.62 1.1003 0.9791 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K12 compound treatment 438460.0 -5020.0 -0.05 325630.0 -70700.0 -0.74 -0.5601 -0.754 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K13 compound treatment 408240.0 -35200.0 -0.36 436750.0 40400.0 0.42 0.046 0.083 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K14 compound treatment 451230.0 7750.0 0.08 445310.0 49000.0 0.51 0.4183 0.8062 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K15 mock treatment 491600.0 48100.0 0.49 497030.0 101000.0 1.05 1.0916 0.9389 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K16 mock treatment 571230.0 128000.0 1.3 371170.0 -25200.0 -0.26 0.7313 0.5521 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K17 compound treatment 523360.0 79900.0 0.81 410530.0 14200.0 0.15 0.679 0.8228 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K18 compound treatment 468850.0 25400.0 0.26 410210.0 13900.0 0.15 0.2849 0.9631 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K19 compound treatment 446350.0 2870.0 0.03 419000.0 22600.0 0.24 0.1883 0.788 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K20 compound treatment 446750.0 3270.0 0.03 425440.0 29100.0 0.3 0.2389 0.7795 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K21 compound treatment 432930.0 -10600.0 -0.11 363490.0 -32900.0 -0.34 -0.3193 -0.8854 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K22 compound treatment 438580.0 -4900.0 -0.05 373560.0 -22800.0 -0.24 -0.2041 -0.8366 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K23 mock treatment 491270.0 47800.0 0.49 411910.0 15600.0 0.16 0.4586 0.8953 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 K24 mock treatment 469620.0 26100.0 0.27 362210.0 -34100.0 -0.36 -0.0652 -0.1463 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L01 compound treatment 420230.0 -23300.0 -0.24 296890.0 -99500.0 -1.04 -0.904 -0.846 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L02 compound treatment 486010.0 42500.0 0.43 399360.0 3000.0 0.03 0.3278 0.7566 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L03 compound treatment 388720.0 -54800.0 -0.56 344000.0 -52400.0 -0.55 -0.7814 -1.0 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L04 compound treatment 385410.0 -58100.0 -0.59 271140.0 -125000.0 -1.31 -1.345 -0.9349 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L05 compound treatment 399450.0 -44000.0 -0.45 386430.0 -9930.0 -0.1 -0.39 -0.8488 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L06 compound treatment 335750.0 -108000.0 -1.09 364910.0 -31400.0 -0.33 -1.0071 -0.8809 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L07 mock treatment 410490.0 -33000.0 -0.34 357920.0 -38400.0 -0.4 -0.5219 -0.9959 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L08 mock treatment 386200.0 -57300.0 -0.58 428320.0 32000.0 0.33 -0.1748 -0.2603 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L09 compound treatment 418970.0 -24500.0 -0.25 349660.0 -46700.0 -0.49 -0.5221 -0.951 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L10 compound treatment 418750.0 -24700.0 -0.25 385040.0 -11300.0 -0.12 -0.2616 -0.9412 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L11 compound treatment 391260.0 -52200.0 -0.53 315060.0 -81300.0 -0.85 -0.9776 -0.9741 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L12 compound treatment 481290.0 37800.0 0.38 366730.0 -29600.0 -0.31 0.0522 0.1056 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L13 compound treatment 438960.0 -4520.0 -0.05 379200.0 -17200.0 -0.18 -0.1596 -0.8603 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L14 compound treatment 414000.0 -29500.0 -0.3 356650.0 -39700.0 -0.42 -0.5061 -0.987 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L15 mock treatment 502420.0 58900.0 0.6 368680.0 -27700.0 -0.29 0.2184 0.3283 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L16 mock treatment 480070.0 36600.0 0.37 441570.0 45200.0 0.47 0.5979 0.9928 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L17 compound treatment 468510.0 25000.0 0.25 377020.0 -19300.0 -0.2 0.0366 0.1124 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L18 compound treatment 459070.0 15600.0 0.16 361370.0 -35000.0 -0.37 -0.1472 -0.3687 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L19 compound treatment 427250.0 -16200.0 -0.16 357240.0 -39100.0 -0.41 -0.4065 -0.92 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L20 compound treatment 388320.0 -55200.0 -0.56 398150.0 1790.0 0.02 -0.3831 -0.683 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L21 compound treatment 457150.0 13700.0 0.14 364130.0 -32200.0 -0.34 -0.1406 -0.385 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L22 compound treatment 463480.0 20000.0 0.2 350240.0 -46100.0 -0.48 -0.198 -0.3777 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L23 mock treatment 453950.0 10500.0 0.11 377720.0 -18600.0 -0.2 -0.0629 -0.2828 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 L24 mock treatment 436410.0 -7070.0 -0.07 409130.0 12800.0 0.13 0.0438 0.2883 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M01 compound treatment 461340.0 17900.0 0.18 402080.0 5720.0 0.06 0.1707 0.8932 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M02 compound treatment 438880.0 -4600.0 -0.05 405930.0 9570.0 0.1 0.0378 0.3418 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M03 compound treatment 425300.0 -18200.0 -0.18 386880.0 -9480.0 -0.1 -0.2009 -0.9576 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M04 compound treatment 461990.0 18500.0 0.19 357880.0 -38500.0 -0.4 -0.1521 -0.3419 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M05 compound treatment 353920.0 -89600.0 -0.91 364410.0 -31900.0 -0.33 -0.8803 -0.9077 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M06 compound treatment 422120.0 -21400.0 -0.22 403890.0 7530.0 0.08 -0.0977 -0.423 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M07 compound treatment 367240.0 -76200.0 -0.77 342210.0 -54100.0 -0.57 -0.949 -0.9883 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M08 compound treatment 407960.0 -35500.0 -0.36 381070.0 -15300.0 -0.16 -0.3685 -0.9331 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M09 mock treatment 418120.0 -25400.0 -0.26 354080.0 -42300.0 -0.44 -0.4955 -0.9668 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M10 mock treatment 478190.0 34700.0 0.35 460650.0 64300.0 0.67 0.7257 0.9544 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M11 compound treatment 423040.0 -20400.0 -0.21 330470.0 -65900.0 -0.69 -0.6351 -0.8809 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M12 compound treatment 396190.0 -47300.0 -0.48 424360.0 28000.0 0.29 -0.1324 -0.2351 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M13 mock treatment 533500.0 90000.0 0.91 448750.0 52400.0 0.55 1.035 0.9702 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M14 mock treatment 456870.0 13400.0 0.14 401520.0 5160.0 0.05 0.1344 0.9183 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M15 compound treatment 466560.0 23100.0 0.23 389760.0 -6600.0 -0.07 0.1169 0.4783 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M16 compound treatment 445800.0 2320.0 0.02 400520.0 4160.0 0.04 0.0475 0.9581 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M17 compound treatment 456870.0 13400.0 0.14 382760.0 -13600.0 -0.14 -0.0046 -0.0231 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M18 compound treatment 385990.0 -57500.0 -0.58 386160.0 -10200.0 -0.11 -0.4887 -0.8228 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M19 compound treatment 457220.0 13700.0 0.14 345940.0 -50400.0 -0.53 -0.2748 -0.503 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M20 compound treatment 406010.0 -37500.0 -0.38 382840.0 -13500.0 -0.14 -0.3694 -0.9092 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M21 compound treatment 417020.0 -26500.0 -0.27 379530.0 -16800.0 -0.18 -0.3148 -0.979 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M22 compound treatment 391530.0 -52000.0 -0.53 380000.0 -16400.0 -0.17 -0.4945 -0.8909 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M23 compound treatment 384640.0 -58800.0 -0.6 364640.0 -31700.0 -0.33 -0.6578 -0.9616 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 M24 compound treatment 403450.0 -40000.0 -0.41 369280.0 -27100.0 -0.28 -0.4883 -0.9845 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N01 compound treatment 408050.0 -35400.0 -0.36 400040.0 3680.0 0.04 -0.2273 -0.6278 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N02 compound treatment 494580.0 51100.0 0.52 311370.0 -85000.0 -0.89 -0.2625 -0.2547 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N03 compound treatment 392240.0 -51200.0 -0.52 339530.0 -56800.0 -0.6 -0.7892 -0.9978 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N04 compound treatment 405250.0 -38200.0 -0.39 372100.0 -24300.0 -0.25 -0.4545 -0.9788 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N05 compound treatment 426350.0 -17100.0 -0.17 384290.0 -12100.0 -0.13 -0.2125 -0.9877 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N06 compound treatment 429770.0 -13700.0 -0.14 406630.0 10300.0 0.11 -0.0224 -0.1275 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N07 compound treatment 421600.0 -21900.0 -0.22 326760.0 -69600.0 -0.73 -0.6729 -0.8826 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N08 compound treatment 448160.0 4680.0 0.05 368210.0 -28100.0 -0.29 -0.1749 -0.5856 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N09 mock treatment 461450.0 18000.0 0.18 343010.0 -53300.0 -0.56 -0.2661 -0.4526 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N10 mock treatment 452740.0 9260.0 0.09 412540.0 16200.0 0.17 0.1864 0.9614 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N11 compound treatment 394590.0 -48900.0 -0.5 367470.0 -28900.0 -0.3 -0.5654 -0.9717 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N12 compound treatment 426500.0 -17000.0 -0.17 435590.0 39200.0 0.41 0.1686 0.3782 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N13 mock treatment 479600.0 36100.0 0.37 407840.0 11500.0 0.12 0.3446 0.8922 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N14 mock treatment 560330.0 117000.0 1.19 442810.0 46500.0 0.49 1.1838 0.9225 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N15 compound treatment 499490.0 56000.0 0.57 356270.0 -40100.0 -0.42 0.1054 0.1491 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N16 compound treatment 432400.0 -11100.0 -0.11 422170.0 25800.0 0.27 0.1116 0.3809 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N17 compound treatment 439880.0 -3600.0 -0.04 374160.0 -22200.0 -0.23 -0.1904 -0.8085 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N18 compound treatment 438240.0 -5240.0 -0.05 361210.0 -35100.0 -0.37 -0.2981 -0.8011 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N19 compound treatment 398940.0 -44500.0 -0.45 342280.0 -54100.0 -0.57 -0.7207 -0.9938 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N20 compound treatment 423560.0 -19900.0 -0.2 401920.0 5560.0 0.06 -0.102 -0.4839 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N21 compound treatment 448740.0 5260.0 0.05 400660.0 4300.0 0.05 0.0696 0.9964 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N22 compound treatment 477030.0 33500.0 0.34 400160.0 3800.0 0.04 0.2692 0.7844 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N23 compound treatment 399220.0 -44300.0 -0.45 403880.0 7520.0 0.08 -0.2623 -0.5745 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 N24 compound treatment 444560.0 1080.0 0.01 299360.0 -97000.0 -1.02 -0.7109 -0.6995 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O01 compound treatment 376110.0 -67400.0 -0.68 343560.0 -52800.0 -0.55 -0.8753 -0.9944 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O02 compound treatment 438810.0 -4670.0 -0.05 374080.0 -22300.0 -0.23 -0.1986 -0.8339 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O03 compound treatment 377680.0 -65800.0 -0.67 396190.0 -168.0 0.0 -0.4741 -0.709 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O04 compound treatment 368810.0 -74700.0 -0.76 411420.0 15100.0 0.16 -0.425 -0.5483 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O05 compound treatment 418340.0 -25100.0 -0.26 345030.0 -51300.0 -0.54 -0.561 -0.9421 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O06 compound treatment 453520.0 10000.0 0.1 436170.0 39800.0 0.42 0.3671 0.8548 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O07 compound treatment 403200.0 -40300.0 -0.41 422750.0 26400.0 0.28 -0.0939 -0.1902 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O08 compound treatment 426590.0 -16900.0 -0.17 393510.0 -2850.0 -0.03 -0.1425 -0.8177 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O09 compound treatment 411390.0 -32100.0 -0.33 394810.0 -1550.0 -0.02 -0.2421 -0.7414 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O10 compound treatment 399540.0 -43900.0 -0.45 327520.0 -68800.0 -0.72 -0.8258 -0.9734 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O11 mock treatment 463110.0 19600.0 0.2 290840.0 -106000.0 -1.11 -0.6407 -0.5703 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O12 mock treatment 432410.0 -11100.0 -0.11 459240.0 62900.0 0.66 0.3863 0.578 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O13 compound treatment 443410.0 -74.3 0.0 335740.0 -60600.0 -0.64 -0.4496 -0.7079 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O14 compound treatment 402730.0 -40800.0 -0.41 353080.0 -43300.0 -0.45 -0.6135 -0.999 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O15 compound treatment 471040.0 27600.0 0.28 361780.0 -34600.0 -0.36 -0.0582 -0.127 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O16 compound treatment 473030.0 29500.0 0.3 468480.0 72100.0 0.76 0.7466 0.9182 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O17 compound treatment 448000.0 4520.0 0.05 394720.0 -1640.0 -0.02 0.0203 0.4146 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O18 compound treatment 466090.0 22600.0 0.23 370460.0 -25900.0 -0.27 -0.0294 -0.0828 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O19 compound treatment 449780.0 6300.0 0.06 347950.0 -48400.0 -0.51 -0.3134 -0.6131 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O20 compound treatment 377650.0 -65800.0 -0.67 341530.0 -54800.0 -0.57 -0.8793 -0.9971 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O21 compound treatment 414360.0 -29100.0 -0.3 358670.0 -37700.0 -0.39 -0.4885 -0.9899 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O22 compound treatment 421650.0 -21800.0 -0.22 353010.0 -43300.0 -0.45 -0.478 -0.9457 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O23 compound treatment 418770.0 -24700.0 -0.25 380130.0 -16200.0 -0.17 -0.2978 -0.982 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 O24 compound treatment 408640.0 -34800.0 -0.35 415260.0 18900.0 0.2 -0.1103 -0.272 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P01 compound treatment 314430.0 -129000.0 -1.31 381240.0 -15100.0 -0.16 -1.0393 -0.7868 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P02 compound treatment 421230.0 -22300.0 -0.23 410940.0 14600.0 0.15 -0.0519 -0.1901 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P03 compound treatment 362900.0 -80600.0 -0.82 328650.0 -67700.0 -0.71 -1.0807 -0.9974 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P04 compound treatment 405600.0 -37900.0 -0.38 417760.0 21400.0 0.22 -0.1137 -0.2551 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P05 compound treatment 326590.0 -117000.0 -1.19 343170.0 -53200.0 -0.56 -1.234 -0.9405 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P06 compound treatment 365230.0 -78300.0 -0.8 338490.0 -57900.0 -0.61 -0.991 -0.991 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P07 compound treatment 373480.0 -70000.0 -0.71 359240.0 -37100.0 -0.39 -0.778 -0.9596 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P08 compound treatment 409490.0 -34000.0 -0.35 337710.0 -58600.0 -0.61 -0.6788 -0.9629 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P09 compound treatment 368960.0 -74500.0 -0.76 326560.0 -69800.0 -0.73 -1.0526 -0.9998 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P10 compound treatment 399200.0 -44300.0 -0.45 358000.0 -38400.0 -0.4 -0.6024 -0.9984 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P11 mock treatment 381410.0 -62100.0 -0.63 352800.0 -43600.0 -0.46 -0.7688 -0.9874 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P12 mock treatment 369540.0 -73900.0 -0.75 362690.0 -33700.0 -0.35 -0.7808 -0.9406 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P13 compound treatment 374790.0 -68700.0 -0.7 357000.0 -39400.0 -0.41 -0.7852 -0.9685 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P14 compound treatment 362530.0 -81000.0 -0.82 374720.0 -21600.0 -0.23 -0.742 -0.8696 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P15 compound treatment 378720.0 -64800.0 -0.66 323550.0 -72800.0 -0.76 -1.0048 -0.9973 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P16 compound treatment 427300.0 -16200.0 -0.16 358800.0 -37600.0 -0.39 -0.3946 -0.9251 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P17 compound treatment 382930.0 -60600.0 -0.62 358610.0 -37700.0 -0.4 -0.7148 -0.9772 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P18 compound treatment 349920.0 -93600.0 -0.95 348520.0 -47800.0 -0.5 -1.0267 -0.9553 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P19 compound treatment 368230.0 -75300.0 -0.76 324320.0 -72000.0 -0.75 -1.0745 -1.0 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P20 compound treatment 401810.0 -41700.0 -0.42 341550.0 -54800.0 -0.57 -0.7055 -0.9888 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P21 compound treatment 393850.0 -49600.0 -0.5 376340.0 -20000.0 -0.21 -0.505 -0.9244 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P22 compound treatment 367290.0 -76200.0 -0.77 378530.0 -17800.0 -0.19 -0.6796 -0.8532 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P23 compound treatment 321170.0 -122000.0 -1.24 274910.0 -121000.0 -1.27 -1.7787 -0.9999 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2101 P24 compound treatment 398850.0 -44600.0 -0.45 395470.0 -888.0 -0.01 -0.3273 -0.7215 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A01 compound treatment 336810.0 -128000.0 -1.3 378350.0 -75000.0 -0.79 -1.4778 -0.9705 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A02 compound treatment 219210.0 -246000.0 -2.5 197280.0 -256000.0 -2.68 -3.6644 -0.9994 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A03 compound treatment 433280.0 -31900.0 -0.32 404430.0 -48900.0 -0.51 -0.5914 -0.9756 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A04 compound treatment 402720.0 -62500.0 -0.63 414240.0 -39100.0 -0.41 -0.7383 -0.9775 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A05 compound treatment 399840.0 -65300.0 -0.66 385550.0 -67800.0 -0.71 -0.9716 -0.9994 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A06 compound treatment 362280.0 -103000.0 -1.05 340660.0 -113000.0 -1.18 -1.5741 -0.9982 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A07 compound treatment 371320.0 -93900.0 -0.95 248410.0 -205000.0 -2.15 -2.1925 -0.9333 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A08 compound treatment 299930.0 -165000.0 -1.68 155780.0 -298000.0 -3.12 -3.3918 -0.9579 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A09 compound treatment 390820.0 -74400.0 -0.76 346300.0 -107000.0 -1.12 -1.3272 -0.9815 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A10 compound treatment 241790.0 -223000.0 -2.27 261490.0 -192000.0 -2.01 -3.0264 -0.9982 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A11 compound treatment 458270.0 -6910.0 -0.07 476430.0 23100.0 0.24 0.1216 0.4823 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A12 compound treatment 332490.0 -133000.0 -1.35 332560.0 -121000.0 -1.27 -1.8481 -0.9995 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A13 mock treatment 450430.0 -14700.0 -0.15 445660.0 -7660.0 -0.08 -0.1627 -0.9572 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A14 mock treatment 430280.0 -34900.0 -0.35 473350.0 20000.0 0.21 -0.1024 -0.2484 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A15 compound treatment 300250.0 -165000.0 -1.68 325620.0 -128000.0 -1.34 -2.1312 -0.9938 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A16 compound treatment 336280.0 -129000.0 -1.31 396160.0 -57200.0 -0.6 -1.3497 -0.9371 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A17 compound treatment 227840.0 -237000.0 -2.41 325770.0 -128000.0 -1.34 -2.6504 -0.9612 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A18 compound treatment 133600.0 -332000.0 -3.37 171560.0 -282000.0 -2.95 -4.4701 -0.9978 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A19 compound treatment 234240.0 -231000.0 -2.35 366610.0 -86700.0 -0.91 -2.3019 -0.9147 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A20 compound treatment 224890.0 -240000.0 -2.44 256530.0 -197000.0 -2.06 -3.1846 -0.9965 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A21 compound treatment 463590.0 -1590.0 -0.02 372380.0 -80900.0 -0.85 -0.6111 -0.7204 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A22 compound treatment 277020.0 -188000.0 -1.91 401500.0 -51800.0 -0.54 -1.736 -0.8734 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A23 compound treatment 426420.0 -38800.0 -0.39 483790.0 30500.0 0.32 -0.0528 -0.1041 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 A24 compound treatment 378560.0 -86600.0 -0.88 403630.0 -49700.0 -0.52 -0.9905 -0.9686 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B01 compound treatment 516210.0 51000.0 0.52 480060.0 26700.0 0.28 0.5648 0.9582 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B02 compound treatment 351690.0 -113000.0 -1.15 389690.0 -63600.0 -0.67 -1.2869 -0.9661 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B03 compound treatment 453990.0 -11200.0 -0.11 391360.0 -62000.0 -0.65 -0.5394 -0.8185 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B04 compound treatment 439750.0 -25400.0 -0.26 375430.0 -77900.0 -0.82 -0.7598 -0.8876 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B05 compound treatment 501950.0 36800.0 0.37 360410.0 -92900.0 -0.97 -0.4241 -0.4067 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B06 compound treatment 382400.0 -82800.0 -0.84 413640.0 -39700.0 -0.42 -0.8888 -0.9472 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B07 compound treatment 455920.0 -9260.0 -0.09 399520.0 -53800.0 -0.56 -0.4651 -0.8138 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B08 compound treatment 476540.0 11400.0 0.12 346260.0 -107000.0 -1.12 -0.7115 -0.631 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B09 compound treatment 430930.0 -34200.0 -0.35 442400.0 -10900.0 -0.11 -0.327 -0.8926 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B10 compound treatment 463860.0 -1320.0 -0.01 388570.0 -64800.0 -0.68 -0.4892 -0.7209 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B11 compound treatment 420200.0 -45000.0 -0.46 416690.0 -36600.0 -0.38 -0.5946 -0.9962 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B12 compound treatment 424480.0 -40700.0 -0.41 366100.0 -87200.0 -0.91 -0.9386 -0.9357 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B13 mock treatment 532110.0 66900.0 0.68 432320.0 -21000.0 -0.22 0.3254 0.4551 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B14 mock treatment 526150.0 61000.0 0.62 470530.0 17200.0 0.18 0.5656 0.8765 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B15 compound treatment 483880.0 18700.0 0.19 439680.0 -13600.0 -0.14 0.0333 0.1402 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B16 compound treatment 394660.0 -70500.0 -0.72 448530.0 -4790.0 -0.05 -0.5422 -0.7548 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B17 compound treatment 471040.0 5860.0 0.06 426350.0 -27000.0 -0.28 -0.1577 -0.546 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B18 compound treatment 354140.0 -111000.0 -1.13 382830.0 -70500.0 -0.74 -1.3201 -0.9789 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B19 compound treatment 439790.0 -25400.0 -0.26 473850.0 20500.0 0.22 -0.0303 -0.0903 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B20 compound treatment 435060.0 -30100.0 -0.31 384920.0 -68400.0 -0.72 -0.7232 -0.928 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B21 compound treatment 487550.0 22400.0 0.23 462150.0 8830.0 0.09 0.2262 0.9214 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B22 compound treatment 438180.0 -27000.0 -0.27 417720.0 -35600.0 -0.37 -0.4577 -0.9886 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B23 compound treatment 452010.0 -13200.0 -0.13 431310.0 -22000.0 -0.23 -0.2577 -0.9665 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 B24 compound treatment 466730.0 1550.0 0.02 445230.0 -8090.0 -0.08 -0.0488 -0.5656 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C01 compound treatment 412480.0 -52700.0 -0.54 354360.0 -99000.0 -1.04 -1.1118 -0.9527 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C02 compound treatment 327210.0 -138000.0 -1.4 316260.0 -137000.0 -1.44 -2.0068 -0.9999 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C03 compound treatment 330420.0 -135000.0 -1.37 344200.0 -109000.0 -1.14 -1.7768 -0.996 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C04 compound treatment 351210.0 -114000.0 -1.16 364400.0 -88900.0 -0.93 -1.4777 -0.9942 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C05 compound treatment 329730.0 -135000.0 -1.38 390090.0 -63200.0 -0.66 -1.4417 -0.9438 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C06 compound treatment 230110.0 -235000.0 -2.39 103200.0 -350000.0 -3.67 -4.2831 -0.9784 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C07 compound treatment 377600.0 -87600.0 -0.89 428490.0 -24800.0 -0.26 -0.8133 -0.8771 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C08 compound treatment 358490.0 -107000.0 -1.08 321640.0 -132000.0 -1.38 -1.7422 -0.9929 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C09 compound treatment 242940.0 -222000.0 -2.26 263140.0 -190000.0 -1.99 -3.0059 -0.9981 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C10 compound treatment 393650.0 -71500.0 -0.73 353320.0 -100000.0 -1.05 -1.2548 -0.984 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C11 mock treatment 384580.0 -80600.0 -0.82 425360.0 -28000.0 -0.29 -0.7863 -0.904 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C12 mock treatment 410120.0 -55100.0 -0.56 424690.0 -28600.0 -0.3 -0.6077 -0.9573 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C13 compound treatment 422050.0 -43100.0 -0.44 396590.0 -56700.0 -0.59 -0.7302 -0.9888 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C14 compound treatment 291540.0 -174000.0 -1.76 275320.0 -178000.0 -1.87 -2.5665 -0.9996 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C15 mock treatment 461200.0 -3980.0 -0.04 451230.0 -2090.0 -0.02 -0.0441 -0.9587 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C16 mock treatment 465230.0 54.6 0.0 393090.0 -60200.0 -0.63 -0.4458 -0.7065 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C17 compound treatment 367750.0 -97400.0 -0.99 371730.0 -81600.0 -0.85 -1.3046 -0.9973 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C18 compound treatment 367900.0 -97300.0 -0.99 359770.0 -93600.0 -0.98 -1.3921 -1.0 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C19 compound treatment 339360.0 -126000.0 -1.28 380830.0 -72500.0 -0.76 -1.4411 -0.9691 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C20 compound treatment 377010.0 -88200.0 -0.9 321890.0 -131000.0 -1.38 -1.6073 -0.9783 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C21 compound treatment 415810.0 -49400.0 -0.5 361120.0 -92200.0 -0.97 -1.0378 -0.9534 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C22 compound treatment 433090.0 -32100.0 -0.33 382570.0 -70800.0 -0.74 -0.7547 -0.932 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C23 compound treatment 352740.0 -112000.0 -1.14 359610.0 -93700.0 -0.98 -1.5022 -0.9972 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 C24 compound treatment 407780.0 -57400.0 -0.58 348400.0 -105000.0 -1.1 -1.1898 -0.956 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D01 compound treatment 416540.0 -48600.0 -0.49 435000.0 -18300.0 -0.19 -0.4852 -0.9151 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D02 compound treatment 416970.0 -48200.0 -0.49 370500.0 -82800.0 -0.87 -0.96 -0.9634 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D03 compound treatment 331360.0 -134000.0 -1.36 358950.0 -94400.0 -0.99 -1.6607 -0.9877 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D04 compound treatment 397320.0 -67900.0 -0.69 310680.0 -143000.0 -1.49 -1.5444 -0.9383 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D05 compound treatment 345540.0 -120000.0 -1.22 400090.0 -53200.0 -0.56 -1.254 -0.9375 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D06 compound treatment 373920.0 -91300.0 -0.93 371000.0 -82300.0 -0.86 -1.2656 -0.9993 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D07 compound treatment 330050.0 -135000.0 -1.37 378040.0 -75300.0 -0.79 -1.5287 -0.9654 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D08 compound treatment 449520.0 -15700.0 -0.16 513860.0 60500.0 0.63 0.336 0.5138 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D09 compound treatment 450960.0 -14200.0 -0.14 374530.0 -78800.0 -0.83 -0.6859 -0.8184 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D10 compound treatment 398500.0 -66700.0 -0.68 443310.0 -10000.0 -0.1 -0.5533 -0.807 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D11 mock treatment 405000.0 -60200.0 -0.61 503100.0 49800.0 0.52 -0.0636 -0.0791 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D12 mock treatment 467730.0 2550.0 0.03 475200.0 21900.0 0.23 0.1804 0.7822 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D13 compound treatment 448430.0 -16700.0 -0.17 391410.0 -61900.0 -0.65 -0.579 -0.8634 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D14 compound treatment 320930.0 -144000.0 -1.47 290880.0 -162000.0 -1.7 -2.24 -0.9972 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D15 mock treatment 446310.0 -18900.0 -0.19 486950.0 33600.0 0.35 0.1136 0.2832 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D16 mock treatment 438730.0 -26400.0 -0.27 498630.0 45300.0 0.47 0.1456 0.267 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D17 compound treatment 390150.0 -75000.0 -0.76 456060.0 2740.0 0.03 -0.5188 -0.68 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D18 compound treatment 382470.0 -82700.0 -0.84 459470.0 6150.0 0.06 -0.5487 -0.651 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D19 compound treatment 457180.0 -8000.0 -0.08 432640.0 -20700.0 -0.22 -0.2107 -0.9104 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D20 compound treatment 223290.0 -242000.0 -2.46 140320.0 -313000.0 -3.28 -4.0571 -0.9899 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D21 compound treatment 413310.0 -51900.0 -0.53 418560.0 -34800.0 -0.36 -0.6302 -0.9837 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D22 compound treatment 486300.0 21100.0 0.21 411600.0 -41700.0 -0.44 -0.1573 -0.323 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D23 compound treatment 357070.0 -108000.0 -1.1 389290.0 -64000.0 -0.67 -1.2512 -0.972 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 D24 compound treatment 375290.0 -89900.0 -0.91 396960.0 -56400.0 -0.59 -1.0635 -0.9777 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E01 mock treatment 404860.0 -60300.0 -0.61 400800.0 -52500.0 -0.55 -0.8225 -0.9986 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E02 mock treatment 503100.0 37900.0 0.39 489440.0 36100.0 0.38 0.5401 1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E03 compound treatment 380660.0 -84500.0 -0.86 507000.0 53700.0 0.56 -0.2096 -0.2042 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E04 compound treatment 385490.0 -79700.0 -0.81 255860.0 -197000.0 -2.07 -2.0355 -0.9162 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E05 compound treatment 267800.0 -197000.0 -2.01 319450.0 -134000.0 -1.4 -2.4101 -0.9847 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E06 compound treatment 436320.0 -28900.0 -0.29 426400.0 -26900.0 -0.28 -0.4068 -0.9998 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E07 compound treatment 396990.0 -68200.0 -0.69 291330.0 -162000.0 -1.7 -1.6901 -0.9219 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E08 compound treatment 360160.0 -105000.0 -1.07 168390.0 -285000.0 -2.99 -2.8656 -0.9039 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E09 mock treatment 510510.0 45300.0 0.46 439410.0 -13900.0 -0.15 0.2227 0.4609 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E10 mock treatment 502910.0 37700.0 0.38 418310.0 -35000.0 -0.37 0.0118 0.0222 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E11 compound treatment 455680.0 -9500.0 -0.1 343870.0 -109000.0 -1.15 -0.8791 -0.7639 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E12 compound treatment 387160.0 -78000.0 -0.79 456640.0 3320.0 0.03 -0.536 -0.6754 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E13 compound treatment 324340.0 -141000.0 -1.43 375330.0 -78000.0 -0.82 -1.5898 -0.9647 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E14 compound treatment 434150.0 -31000.0 -0.32 374350.0 -79000.0 -0.83 -0.808 -0.9125 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E15 compound treatment 336280.0 -129000.0 -1.31 333090.0 -120000.0 -1.26 -1.817 -0.9998 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E16 compound treatment 459770.0 -5410.0 -0.05 443130.0 -10200.0 -0.11 -0.1143 -0.9522 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E17 mock treatment 516870.0 51700.0 0.53 466240.0 12900.0 0.14 0.4672 0.8612 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E18 mock treatment 508230.0 43100.0 0.44 525230.0 71900.0 0.75 0.8421 0.9666 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E19 compound treatment 396840.0 -68300.0 -0.69 386530.0 -66800.0 -0.7 -0.9859 -1.0 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E20 compound treatment 464510.0 -665.0 -0.01 417680.0 -35600.0 -0.37 -0.2688 -0.7198 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E21 compound treatment 297280.0 -168000.0 -1.71 312350.0 -141000.0 -1.48 -2.2509 -0.9974 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E22 compound treatment 417310.0 -47900.0 -0.49 426880.0 -26400.0 -0.28 -0.5398 -0.9644 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E23 compound treatment 366140.0 -99000.0 -1.01 271220.0 -182000.0 -1.91 -2.0608 -0.9553 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 E24 compound treatment 471800.0 6620.0 0.07 392590.0 -60700.0 -0.64 -0.4023 -0.6288 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F01 mock treatment 477730.0 12600.0 0.13 444900.0 -8420.0 -0.09 0.0278 0.1793 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F02 mock treatment 447010.0 -18200.0 -0.18 428330.0 -25000.0 -0.26 -0.3157 -0.9854 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F03 compound treatment 356810.0 -108000.0 -1.1 375100.0 -78200.0 -0.82 -1.3582 -0.9894 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F04 compound treatment 358030.0 -107000.0 -1.09 348890.0 -104000.0 -1.09 -1.5436 -1.0 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F05 compound treatment 436640.0 -28500.0 -0.29 404390.0 -48900.0 -0.51 -0.5676 -0.9636 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F06 compound treatment 308740.0 -156000.0 -1.59 199910.0 -253000.0 -2.66 -3.0016 -0.9699 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F07 compound treatment 315520.0 -150000.0 -1.52 258250.0 -195000.0 -2.04 -2.5206 -0.9894 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F08 compound treatment 421010.0 -44200.0 -0.45 458720.0 5400.0 0.06 -0.2774 -0.6131 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F09 mock treatment 418370.0 -46800.0 -0.48 525050.0 71700.0 0.75 0.1951 0.2193 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F10 mock treatment 523290.0 58100.0 0.59 345550.0 -108000.0 -1.13 -0.3809 -0.2989 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F11 compound treatment 434400.0 -30800.0 -0.31 405550.0 -47800.0 -0.5 -0.5751 -0.9744 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F12 compound treatment 420360.0 -44800.0 -0.46 435540.0 -17800.0 -0.19 -0.4538 -0.9222 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F13 compound treatment 343070.0 -122000.0 -1.24 343450.0 -110000.0 -1.15 -1.6914 -0.9993 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F14 compound treatment 344180.0 -121000.0 -1.23 421040.0 -32300.0 -0.34 -1.1086 -0.8693 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F15 compound treatment 467940.0 2760.0 0.03 422400.0 -30900.0 -0.32 -0.2092 -0.6434 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F16 compound treatment 365310.0 -99900.0 -1.01 382890.0 -70400.0 -0.74 -1.2394 -0.9878 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F17 mock treatment 472400.0 7220.0 0.07 483220.0 29900.0 0.31 0.2734 0.8498 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F18 mock treatment 442360.0 -22800.0 -0.23 475770.0 22400.0 0.24 0.0024 0.0072 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F19 compound treatment 488260.0 23100.0 0.23 440160.0 -13200.0 -0.14 0.0684 0.2512 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F20 compound treatment 472860.0 7680.0 0.08 535730.0 82400.0 0.86 0.6658 0.7679 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F21 compound treatment 482240.0 17100.0 0.17 466340.0 13000.0 0.14 0.2191 0.9929 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F22 compound treatment 338560.0 -127000.0 -1.29 283770.0 -170000.0 -1.78 -2.166 -0.9875 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F23 compound treatment 404640.0 -60500.0 -0.62 456610.0 3290.0 0.03 -0.4106 -0.6665 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 F24 compound treatment 478000.0 12800.0 0.13 442110.0 -11200.0 -0.12 0.0091 0.0518 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G01 compound treatment 306400.0 -159000.0 -1.61 329700.0 -124000.0 -1.3 -2.0568 -0.9941 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G02 compound treatment 447100.0 -18100.0 -0.18 464720.0 11400.0 0.12 -0.0454 -0.2074 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G03 mock treatment 492070.0 26900.0 0.27 490480.0 37200.0 0.39 0.4686 0.985 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G04 mock treatment 456730.0 -8450.0 -0.09 340890.0 -112000.0 -1.18 -0.8937 -0.7566 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G05 compound treatment 416750.0 -48400.0 -0.49 349070.0 -104000.0 -1.09 -1.1203 -0.9352 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G06 compound treatment 318170.0 -147000.0 -1.49 276770.0 -177000.0 -1.85 -2.3644 -0.9944 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G07 compound treatment 336540.0 -129000.0 -1.31 276380.0 -177000.0 -1.85 -2.2352 -0.9854 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G08 compound treatment 350200.0 -115000.0 -1.17 289080.0 -164000.0 -1.72 -2.043 -0.9822 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G09 compound treatment 283720.0 -181000.0 -1.84 138720.0 -315000.0 -3.3 -3.6347 -0.9623 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G10 compound treatment 392080.0 -73100.0 -0.74 392180.0 -61100.0 -0.64 -0.9782 -0.9973 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G11 compound treatment 306880.0 -158000.0 -1.61 280480.0 -173000.0 -1.81 -2.418 -0.9983 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G12 compound treatment 429540.0 -35600.0 -0.36 358010.0 -95300.0 -1.0 -0.9622 -0.9058 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G13 compound treatment 301920.0 -163000.0 -1.66 351420.0 -102000.0 -1.07 -1.9281 -0.9773 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G14 compound treatment 346140.0 -119000.0 -1.21 262180.0 -191000.0 -2.0 -2.2715 -0.9709 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G15 compound treatment 393030.0 -72100.0 -0.73 332090.0 -121000.0 -1.27 -1.4166 -0.9659 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G16 compound treatment 467430.0 2250.0 0.02 395680.0 -57600.0 -0.6 -0.4108 -0.6798 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G17 compound treatment 374400.0 -90800.0 -0.92 262190.0 -191000.0 -2.0 -2.0683 -0.9381 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G18 compound treatment 482910.0 17700.0 0.18 443110.0 -10200.0 -0.11 0.0518 0.2471 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G19 mock treatment 473860.0 8680.0 0.09 531950.0 78600.0 0.82 0.6449 0.7784 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G20 mock treatment 426790.0 -38400.0 -0.39 518720.0 65400.0 0.69 0.2087 0.2647 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G21 compound treatment 421290.0 -43900.0 -0.45 359200.0 -94100.0 -0.99 -1.0127 -0.9357 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G22 compound treatment 359320.0 -106000.0 -1.08 289760.0 -164000.0 -1.71 -1.9724 -0.9748 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G23 compound treatment 463280.0 -1900.0 -0.02 443480.0 -9840.0 -0.1 -0.0865 -0.8249 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 G24 compound treatment 380650.0 -84500.0 -0.86 422400.0 -30900.0 -0.32 -0.8365 -0.9112 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H01 compound treatment 344750.0 -120000.0 -1.22 423290.0 -30000.0 -0.31 -1.0878 -0.8609 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H02 compound treatment 375770.0 -89400.0 -0.91 331840.0 -121000.0 -1.27 -1.5425 -0.9863 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H03 mock treatment 446080.0 -19100.0 -0.19 449320.0 -4000.0 -0.04 -0.1669 -0.8405 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H04 mock treatment 396960.0 -68200.0 -0.69 407010.0 -46300.0 -0.49 -0.8333 -0.9848 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H05 compound treatment 385390.0 -79800.0 -0.81 325390.0 -128000.0 -1.34 -1.5211 -0.971 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H06 compound treatment 493830.0 28700.0 0.29 322000.0 -131000.0 -1.38 -0.767 -0.5454 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H07 compound treatment 409350.0 -55800.0 -0.57 380900.0 -72400.0 -0.76 -0.9377 -0.9897 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H08 compound treatment 313800.0 -151000.0 -1.54 295250.0 -158000.0 -1.66 -2.2588 -0.9993 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H09 compound treatment 424000.0 -41200.0 -0.42 411480.0 -41800.0 -0.44 -0.6059 -0.9997 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H10 compound treatment 282840.0 -182000.0 -1.85 212250.0 -241000.0 -2.53 -3.0962 -0.9884 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H11 compound treatment 247550.0 -218000.0 -2.21 244890.0 -208000.0 -2.18 -3.108 -1.0 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H12 compound treatment 357320.0 -108000.0 -1.1 225860.0 -227000.0 -2.38 -2.4602 -0.9379 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H13 compound treatment 473460.0 8280.0 0.08 365020.0 -88300.0 -0.93 -0.5947 -0.6401 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H14 compound treatment 224670.0 -241000.0 -2.44 39650.0 -414000.0 -4.33 -4.793 -0.9632 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H15 compound treatment 459040.0 -6140.0 -0.06 433840.0 -19500.0 -0.2 -0.1884 -0.8828 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H16 compound treatment 394570.0 -70600.0 -0.72 462370.0 9050.0 0.09 -0.4403 -0.6084 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H17 compound treatment 494270.0 29100.0 0.3 423520.0 -29800.0 -0.31 -0.0117 -0.0273 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H18 compound treatment 275920.0 -189000.0 -1.92 70790.0 -383000.0 -4.01 -4.194 -0.9434 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H19 mock treatment 439460.0 -25700.0 -0.26 465600.0 12300.0 0.13 -0.0938 -0.3221 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H20 mock treatment 490800.0 25600.0 0.26 541350.0 88000.0 0.92 0.8363 0.8726 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H21 compound treatment 466130.0 955.0 0.01 458500.0 5180.0 0.05 0.0452 0.8205 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H22 compound treatment 339560.0 -126000.0 -1.28 262450.0 -191000.0 -2.0 -2.3167 -0.9765 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H23 compound treatment 376480.0 -88700.0 -0.9 332070.0 -121000.0 -1.27 -1.5357 -0.9859 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 H24 compound treatment 493240.0 28100.0 0.29 469780.0 16500.0 0.17 0.3236 0.971 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I01 compound treatment 351720.0 -113000.0 -1.15 394990.0 -58300.0 -0.61 -1.2474 -0.9559 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I02 compound treatment 293830.0 -171000.0 -1.74 353170.0 -100000.0 -1.05 -1.9732 -0.9706 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I03 compound treatment 377210.0 -88000.0 -0.89 335810.0 -118000.0 -1.23 -1.5027 -0.9876 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I04 compound treatment 374500.0 -90700.0 -0.92 84320.0 -369000.0 -3.87 -3.3854 -0.8518 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I05 mock treatment 540760.0 75600.0 0.77 373020.0 -80300.0 -0.84 -0.0518 -0.0455 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I06 mock treatment 429630.0 -35500.0 -0.36 403290.0 -50000.0 -0.52 -0.6261 -0.9835 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I07 compound treatment 386770.0 -78400.0 -0.8 334580.0 -119000.0 -1.24 -1.4431 -0.9768 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I08 compound treatment 468600.0 3420.0 0.03 393350.0 -60000.0 -0.63 -0.4197 -0.6669 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I09 compound treatment 409460.0 -55700.0 -0.57 406400.0 -46900.0 -0.49 -0.748 -0.9975 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I10 compound treatment 381180.0 -84000.0 -0.85 273830.0 -179000.0 -1.88 -1.9334 -0.9361 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I11 compound treatment 328530.0 -137000.0 -1.39 220430.0 -233000.0 -2.44 -2.7073 -0.9643 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I12 compound treatment 370450.0 -94700.0 -0.96 258400.0 -195000.0 -2.04 -2.1248 -0.9411 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I13 compound treatment 416350.0 -48800.0 -0.5 343930.0 -109000.0 -1.15 -1.1613 -0.9298 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I14 compound treatment 433010.0 -32200.0 -0.33 418970.0 -34400.0 -0.36 -0.4856 -0.9988 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I15 compound treatment 483480.0 18300.0 0.19 415260.0 -38100.0 -0.4 -0.1505 -0.3419 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I16 compound treatment 386030.0 -79100.0 -0.8 307230.0 -146000.0 -1.53 -1.6511 -0.9549 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I17 compound treatment 369290.0 -95900.0 -0.97 371520.0 -81800.0 -0.86 -1.295 -0.998 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I18 compound treatment 563540.0 98400.0 1.0 486300.0 33000.0 0.35 0.9511 0.8993 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I19 compound treatment 475060.0 9880.0 0.1 301140.0 -152000.0 -1.59 -1.0564 -0.6613 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I20 compound treatment 410210.0 -55000.0 -0.56 351590.0 -102000.0 -1.07 -1.1487 -0.9545 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I21 mock treatment 557150.0 92000.0 0.93 449140.0 -4180.0 -0.04 0.6299 0.6732 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I22 mock treatment 514150.0 49000.0 0.5 495760.0 42400.0 0.44 0.6663 0.9984 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I23 compound treatment 403380.0 -61800.0 -0.63 343450.0 -110000.0 -1.15 -1.2581 -0.9594 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 I24 compound treatment 436320.0 -28900.0 -0.29 459360.0 6040.0 0.06 -0.1626 -0.5421 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J01 compound treatment 420770.0 -44400.0 -0.45 450900.0 -2420.0 -0.03 -0.337 -0.7457 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J02 compound treatment 430150.0 -35000.0 -0.36 364420.0 -88900.0 -0.93 -0.9103 -0.9129 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J03 compound treatment 394760.0 -70400.0 -0.72 322360.0 -131000.0 -1.37 -1.4762 -0.9539 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J04 compound treatment 450520.0 -14700.0 -0.15 462590.0 9270.0 0.1 -0.0366 -0.2061 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J05 mock treatment 403060.0 -62100.0 -0.63 439420.0 -13900.0 -0.15 -0.5493 -0.848 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J06 mock treatment 369400.0 -95800.0 -0.97 480000.0 26700.0 0.28 -0.4906 -0.4844 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J07 compound treatment 308530.0 -157000.0 -1.59 378840.0 -74500.0 -0.78 -1.6774 -0.9462 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J08 compound treatment 126730.0 -338000.0 -3.44 12500.0 -441000.0 -4.62 -5.6979 -0.9895 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J09 compound treatment 445880.0 -19300.0 -0.2 306800.0 -147000.0 -1.54 -1.2242 -0.791 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J10 compound treatment 366930.0 -98200.0 -1.0 421850.0 -31500.0 -0.33 -0.9391 -0.8932 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J11 compound treatment 408750.0 -56400.0 -0.57 403420.0 -49900.0 -0.52 -0.7752 -0.9989 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J12 compound treatment 212020.0 -253000.0 -2.57 76700.0 -377000.0 -3.95 -4.6094 -0.9785 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J13 compound treatment 356230.0 -109000.0 -1.11 352030.0 -101000.0 -1.06 -1.5333 -0.9998 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J14 compound treatment 518080.0 52900.0 0.54 487860.0 34500.0 0.36 0.636 0.9814 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J15 compound treatment 455740.0 -9440.0 -0.1 364340.0 -89000.0 -0.93 -0.727 -0.7757 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J16 compound treatment 459610.0 -5570.0 -0.06 453690.0 368.0 0.0 -0.0373 -0.6573 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J17 compound treatment 473080.0 7900.0 0.08 466120.0 12800.0 0.13 0.1516 0.97 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J18 compound treatment 458720.0 -6460.0 -0.07 359480.0 -93800.0 -0.98 -0.7416 -0.7526 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J19 compound treatment 383010.0 -82200.0 -0.83 392350.0 -61000.0 -0.64 -1.0421 -0.9913 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J20 compound treatment 389320.0 -75900.0 -0.77 365120.0 -88200.0 -0.92 -1.1985 -0.9959 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J21 mock treatment 505600.0 40400.0 0.41 467680.0 14400.0 0.15 0.3969 0.9071 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J22 mock treatment 401760.0 -63400.0 -0.64 458120.0 4800.0 0.05 -0.4201 -0.65 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J23 compound treatment 435010.0 -30200.0 -0.31 433050.0 -20300.0 -0.21 -0.3669 -0.9839 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 J24 compound treatment 454890.0 -10300.0 -0.1 413790.0 -39500.0 -0.41 -0.3668 -0.8586 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K01 compound treatment 407620.0 -57600.0 -0.58 397780.0 -55500.0 -0.58 -0.8251 -1.0 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K02 compound treatment 403400.0 -61800.0 -0.63 311170.0 -142000.0 -1.49 -1.4971 -0.9262 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K03 compound treatment 552240.0 87100.0 0.88 430880.0 -22400.0 -0.24 0.4594 0.5018 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K04 compound treatment 375680.0 -89500.0 -0.91 295680.0 -158000.0 -1.65 -1.811 -0.9605 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K05 compound treatment 494330.0 29200.0 0.3 324110.0 -129000.0 -1.35 -0.7478 -0.5396 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K06 compound treatment 261960.0 -203000.0 -2.07 155680.0 -298000.0 -3.12 -3.6654 -0.98 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K07 mock treatment 512640.0 47500.0 0.48 453090.0 -232.0 0.0 0.3394 0.7035 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K08 mock treatment 462330.0 -2850.0 -0.03 547210.0 93900.0 0.98 0.6751 0.686 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K09 compound treatment 446020.0 -19200.0 -0.19 453810.0 488.0 0.01 -0.134 -0.6883 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K10 compound treatment 483600.0 18400.0 0.19 420350.0 -33000.0 -0.35 -0.1119 -0.2847 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K11 compound treatment 348380.0 -117000.0 -1.19 267570.0 -186000.0 -1.95 -2.2154 -0.9719 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K12 compound treatment 430880.0 -34300.0 -0.35 279680.0 -174000.0 -1.82 -1.5329 -0.8275 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K13 compound treatment 432060.0 -33100.0 -0.34 373010.0 -80300.0 -0.84 -0.833 -0.9191 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K14 compound treatment 262490.0 -203000.0 -2.06 236240.0 -217000.0 -2.27 -3.0647 -0.9988 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K15 mock treatment 465520.0 345.0 0.0 462170.0 8850.0 0.09 0.068 0.7333 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K16 mock treatment 365710.0 -99500.0 -1.01 480540.0 27200.0 0.29 -0.5131 -0.4885 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K17 compound treatment 440480.0 -24700.0 -0.25 364530.0 -88800.0 -0.93 -0.8353 -0.8669 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K18 compound treatment 314130.0 -151000.0 -1.53 299000.0 -154000.0 -1.62 -2.2287 -0.9997 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K19 compound treatment 460730.0 -4450.0 -0.05 408160.0 -45200.0 -0.47 -0.3665 -0.7711 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K20 compound treatment 499040.0 33900.0 0.34 425000.0 -28300.0 -0.3 0.0335 0.0738 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K21 compound treatment 496990.0 31800.0 0.32 456180.0 2860.0 0.03 0.2498 0.7693 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K22 compound treatment 430620.0 -34600.0 -0.35 416000.0 -37300.0 -0.39 -0.5248 -0.9986 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K23 mock treatment 494270.0 29100.0 0.3 394510.0 -58800.0 -0.62 -0.2267 -0.3316 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 K24 mock treatment 473290.0 8110.0 0.08 460900.0 7580.0 0.08 0.1145 0.9998 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L01 compound treatment 278920.0 -186000.0 -1.89 415290.0 -38000.0 -0.4 -1.6201 -0.8376 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L02 compound treatment 266240.0 -199000.0 -2.02 354890.0 -98400.0 -1.03 -2.1587 -0.9512 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L03 compound treatment 342410.0 -123000.0 -1.25 352930.0 -100000.0 -1.05 -1.6259 -0.9964 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L04 compound treatment 352040.0 -113000.0 -1.15 368880.0 -84400.0 -0.88 -1.4386 -0.9916 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L05 compound treatment 419040.0 -46100.0 -0.47 329680.0 -124000.0 -1.3 -1.2475 -0.9055 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L06 compound treatment 434210.0 -31000.0 -0.31 287940.0 -165000.0 -1.73 -1.4478 -0.8221 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L07 mock treatment 383840.0 -81300.0 -0.83 407560.0 -45800.0 -0.48 -0.9235 -0.9665 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L08 mock treatment 446520.0 -18700.0 -0.19 410500.0 -42800.0 -0.45 -0.4513 -0.9266 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L09 compound treatment 333490.0 -132000.0 -1.34 280030.0 -173000.0 -1.82 -2.2301 -0.9887 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L10 compound treatment 474840.0 9660.0 0.1 339780.0 -114000.0 -1.19 -0.7718 -0.6465 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L11 compound treatment 408960.0 -56200.0 -0.57 392160.0 -61200.0 -0.64 -0.8571 -0.9984 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L12 compound treatment 395850.0 -69300.0 -0.7 514590.0 61300.0 0.64 -0.0442 -0.0464 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L13 compound treatment 270270.0 -195000.0 -1.98 328680.0 -125000.0 -1.31 -2.324 -0.9796 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L14 compound treatment 393440.0 -71700.0 -0.73 401600.0 -51700.0 -0.54 -0.8987 -0.9893 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L15 mock treatment 488160.0 23000.0 0.23 410050.0 -43300.0 -0.45 -0.1554 -0.3048 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L16 mock treatment 501330.0 36200.0 0.37 450020.0 -3300.0 -0.03 0.2353 0.6377 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L17 compound treatment 421860.0 -43300.0 -0.44 484350.0 31000.0 0.33 -0.0814 -0.1487 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L18 compound treatment 509760.0 44600.0 0.45 442400.0 -10900.0 -0.11 0.2395 0.5124 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L19 compound treatment 420450.0 -44700.0 -0.45 326950.0 -126000.0 -1.32 -1.2576 -0.8984 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L20 compound treatment 523880.0 58700.0 0.6 466900.0 13600.0 0.14 0.5224 0.8518 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L21 compound treatment 482250.0 17100.0 0.17 425480.0 -27800.0 -0.29 -0.0836 -0.2462 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L22 compound treatment 442430.0 -22700.0 -0.23 443950.0 -9370.0 -0.1 -0.2329 -0.9273 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L23 mock treatment 491840.0 26700.0 0.27 530790.0 77500.0 0.81 0.7655 0.8946 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 L24 mock treatment 483440.0 18300.0 0.19 478640.0 25300.0 0.27 0.3188 0.9847 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M01 compound treatment 319290.0 -146000.0 -1.48 329060.0 -124000.0 -1.3 -1.9689 -0.9979 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M02 compound treatment 186840.0 -278000.0 -2.83 266660.0 -187000.0 -1.96 -3.383 -0.9838 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M03 compound treatment 347520.0 -118000.0 -1.2 289650.0 -164000.0 -1.71 -2.058 -0.9845 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M04 compound treatment 328690.0 -136000.0 -1.39 305860.0 -147000.0 -1.55 -2.0732 -0.9986 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M05 compound treatment 191630.0 -274000.0 -2.78 170040.0 -283000.0 -2.97 -4.0644 -0.9995 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M06 compound treatment 261160.0 -204000.0 -2.07 158800.0 -295000.0 -3.09 -3.648 -0.9813 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M07 compound treatment 386210.0 -79000.0 -0.8 324380.0 -129000.0 -1.35 -1.5227 -0.9691 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M08 compound treatment 269630.0 -196000.0 -1.99 280450.0 -173000.0 -1.81 -2.6859 -0.9989 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M09 mock treatment 551080.0 85900.0 0.87 522560.0 69200.0 0.73 1.1303 0.9958 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M10 mock treatment 540480.0 75300.0 0.77 509730.0 56400.0 0.59 0.959 0.9918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M11 compound treatment 377390.0 -87800.0 -0.89 431840.0 -21500.0 -0.23 -0.7899 -0.8586 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M12 compound treatment 450720.0 -14500.0 -0.15 394270.0 -59100.0 -0.62 -0.5414 -0.8513 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M13 mock treatment 442690.0 -22500.0 -0.23 423050.0 -30300.0 -0.32 -0.3858 -0.9871 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M14 mock treatment 490400.0 25200.0 0.26 448870.0 -4450.0 -0.05 0.1483 0.5691 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M15 compound treatment 416090.0 -49100.0 -0.5 329870.0 -123000.0 -1.29 -1.2673 -0.9142 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M16 compound treatment 524560.0 59400.0 0.6 416800.0 -36500.0 -0.38 0.1561 0.2185 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M17 compound treatment 314890.0 -150000.0 -1.53 245030.0 -208000.0 -2.18 -2.6231 -0.9848 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M18 compound treatment 402830.0 -62300.0 -0.63 326500.0 -127000.0 -1.33 -1.3876 -0.9426 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M19 compound treatment 450110.0 -15100.0 -0.15 470920.0 17600.0 0.18 0.0221 0.0923 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M20 compound treatment 335950.0 -129000.0 -1.31 379450.0 -73900.0 -0.77 -1.4759 -0.9682 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M21 compound treatment 409050.0 -56100.0 -0.57 384530.0 -68800.0 -0.72 -0.913 -0.9933 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M22 compound treatment 456090.0 -9090.0 -0.09 456160.0 2840.0 0.03 -0.0443 -0.4563 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M23 compound treatment 342080.0 -123000.0 -1.25 367620.0 -85700.0 -0.9 -1.5195 -0.9868 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 M24 compound treatment 281180.0 -184000.0 -1.87 280220.0 -173000.0 -1.81 -2.6046 -0.9999 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N01 compound treatment 378330.0 -86800.0 -0.88 410150.0 -43200.0 -0.45 -0.9439 -0.9518 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N02 compound treatment 455840.0 -9340.0 -0.09 371200.0 -82100.0 -0.86 -0.6755 -0.7803 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N03 compound treatment 407360.0 -57800.0 -0.59 425880.0 -27400.0 -0.29 -0.6188 -0.9459 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N04 compound treatment 396220.0 -69000.0 -0.7 479890.0 26600.0 0.28 -0.2987 -0.3961 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N05 compound treatment 449370.0 -15800.0 -0.16 423840.0 -29500.0 -0.31 -0.332 -0.9536 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N06 compound treatment 429000.0 -36200.0 -0.37 425960.0 -27400.0 -0.29 -0.4627 -0.9924 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N07 compound treatment 345050.0 -120000.0 -1.22 329460.0 -124000.0 -1.3 -1.7808 -0.9995 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N08 compound treatment 418290.0 -46900.0 -0.48 401680.0 -51600.0 -0.54 -0.7195 -0.998 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N09 mock treatment 467930.0 2750.0 0.03 468670.0 15300.0 0.16 0.1335 0.8179 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N10 mock treatment 444920.0 -20300.0 -0.21 376320.0 -77000.0 -0.81 -0.716 -0.86 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N11 compound treatment 457920.0 -7260.0 -0.07 330850.0 -122000.0 -1.28 -0.9595 -0.7465 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N12 compound treatment 346720.0 -118000.0 -1.2 361280.0 -92000.0 -0.96 -1.5331 -0.994 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N13 mock treatment 520930.0 55800.0 0.57 423070.0 -30300.0 -0.32 0.1765 0.2719 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N14 mock treatment 493440.0 28300.0 0.29 462020.0 8700.0 0.09 0.2675 0.8879 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N15 compound treatment 441440.0 -23700.0 -0.24 375520.0 -77800.0 -0.82 -0.747 -0.8787 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N16 compound treatment 537600.0 72400.0 0.74 490940.0 37600.0 0.39 0.7991 0.9572 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N17 compound treatment 499070.0 33900.0 0.34 492610.0 39300.0 0.41 0.5346 0.9961 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N18 compound treatment 419520.0 -45700.0 -0.46 510000.0 56700.0 0.59 0.0918 0.1219 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N19 compound treatment 449220.0 -16000.0 -0.16 426720.0 -26600.0 -0.28 -0.3117 -0.9668 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N20 compound treatment 515930.0 50800.0 0.52 529310.0 76000.0 0.8 0.9277 0.9779 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N21 compound treatment 335130.0 -130000.0 -1.32 364670.0 -88700.0 -0.93 -1.5913 -0.9851 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N22 compound treatment 274880.0 -190000.0 -1.93 300010.0 -153000.0 -1.61 -2.5032 -0.9957 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N23 compound treatment 399320.0 -65900.0 -0.67 413280.0 -40000.0 -0.42 -0.7699 -0.9747 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 N24 compound treatment 456260.0 -8920.0 -0.09 458260.0 4940.0 0.05 -0.0275 -0.2633 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O01 compound treatment 455050.0 -10100.0 -0.1 505780.0 52500.0 0.55 0.3159 0.5649 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O02 compound treatment 290240.0 -175000.0 -1.78 303100.0 -150000.0 -1.57 -2.37 -0.9982 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O03 compound treatment 369220.0 -96000.0 -0.98 437530.0 -15800.0 -0.17 -0.8065 -0.8154 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O04 compound treatment 308000.0 -157000.0 -1.6 283710.0 -170000.0 -1.78 -2.386 -0.9986 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O05 compound treatment 183750.0 -281000.0 -2.86 267630.0 -186000.0 -1.95 -3.398 -0.9824 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O06 compound treatment 172260.0 -293000.0 -2.98 106880.0 -346000.0 -3.63 -4.6715 -0.9951 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O07 compound treatment 315080.0 -150000.0 -1.53 300280.0 -153000.0 -1.6 -2.2124 -0.9997 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O08 compound treatment 277660.0 -188000.0 -1.91 291100.0 -162000.0 -1.7 -2.5493 -0.9984 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O09 compound treatment 276500.0 -189000.0 -1.92 324440.0 -129000.0 -1.35 -2.3106 -0.9853 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O10 compound treatment 347530.0 -118000.0 -1.2 320480.0 -133000.0 -1.39 -1.8296 -0.9971 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O11 mock treatment 407040.0 -58100.0 -0.59 433770.0 -19600.0 -0.2 -0.5626 -0.8997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O12 mock treatment 496800.0 31600.0 0.32 524600.0 71300.0 0.75 0.7553 0.929 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O13 compound treatment 340320.0 -125000.0 -1.27 394240.0 -59100.0 -0.62 -1.3349 -0.9456 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O14 compound treatment 411600.0 -53600.0 -0.54 463300.0 9980.0 0.1 -0.311 -0.5611 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O15 compound treatment 330530.0 -135000.0 -1.37 344570.0 -109000.0 -1.14 -1.7732 -0.9959 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O16 compound treatment 456580.0 -8600.0 -0.09 384220.0 -69100.0 -0.72 -0.5737 -0.7867 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O17 compound treatment 410360.0 -54800.0 -0.56 441200.0 -12100.0 -0.13 -0.4837 -0.8466 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O18 compound treatment 298140.0 -167000.0 -1.7 361290.0 -92000.0 -0.96 -1.8821 -0.9641 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O19 compound treatment 324160.0 -141000.0 -1.43 421950.0 -31400.0 -0.33 -1.2457 -0.8473 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O20 compound treatment 367220.0 -98000.0 -1.0 397820.0 -55500.0 -0.58 -1.1151 -0.9672 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O21 compound treatment 260820.0 -204000.0 -2.08 307490.0 -146000.0 -1.53 -2.5489 -0.9886 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O22 compound treatment 292440.0 -173000.0 -1.76 346740.0 -107000.0 -1.12 -2.0309 -0.9762 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O23 compound treatment 308410.0 -157000.0 -1.59 337760.0 -116000.0 -1.21 -1.9826 -0.9908 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 O24 compound treatment 240060.0 -225000.0 -2.29 277770.0 -176000.0 -1.84 -2.9182 -0.9942 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P01 compound treatment 256720.0 -208000.0 -2.12 251420.0 -202000.0 -2.12 -2.9937 -1.0 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P02 compound treatment 371330.0 -93800.0 -0.95 402680.0 -50600.0 -0.53 -1.0495 -0.9617 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P03 compound treatment 297780.0 -167000.0 -1.7 282880.0 -170000.0 -1.79 -2.4656 -0.9997 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P04 compound treatment 250500.0 -215000.0 -2.18 216990.0 -236000.0 -2.48 -3.2935 -0.998 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P05 compound treatment 102950.0 -362000.0 -3.68 198780.0 -255000.0 -2.67 -4.4887 -0.9875 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P06 compound treatment 352970.0 -112000.0 -1.14 401120.0 -52200.0 -0.55 -1.193 -0.9434 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P07 compound treatment 416160.0 -49000.0 -0.5 413330.0 -40000.0 -0.42 -0.6485 -0.9963 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P08 compound treatment 363880.0 -101000.0 -1.03 354950.0 -98400.0 -1.03 -1.4567 -1.0 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P09 compound treatment 382270.0 -82900.0 -0.84 301380.0 -152000.0 -1.59 -1.7214 -0.9557 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P10 compound treatment 411220.0 -54000.0 -0.55 349770.0 -104000.0 -1.08 -1.1549 -0.95 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P11 mock treatment 308320.0 -157000.0 -1.59 349140.0 -104000.0 -1.09 -1.899 -0.9829 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P12 mock treatment 391680.0 -73500.0 -0.75 350690.0 -103000.0 -1.08 -1.2885 -0.9841 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P13 compound treatment 305600.0 -160000.0 -1.62 300700.0 -153000.0 -1.6 -2.2774 -1.0 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P14 compound treatment 376170.0 -89000.0 -0.9 401510.0 -51800.0 -0.54 -1.0234 -0.9702 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P15 compound treatment 315140.0 -150000.0 -1.52 365880.0 -87400.0 -0.92 -1.7259 -0.9703 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P16 compound treatment 396510.0 -68700.0 -0.7 405820.0 -47500.0 -0.5 -0.8453 -0.9863 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P17 compound treatment 344360.0 -121000.0 -1.23 400580.0 -52700.0 -0.55 -1.2589 -0.935 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P18 compound treatment 338360.0 -127000.0 -1.29 340330.0 -113000.0 -1.18 -1.7484 -0.9991 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P19 compound treatment 379750.0 -85400.0 -0.87 323850.0 -129000.0 -1.36 -1.5731 -0.9767 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P20 compound treatment 308030.0 -157000.0 -1.6 305370.0 -148000.0 -1.55 -2.2253 -0.9999 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P21 compound treatment 260250.0 -205000.0 -2.08 290400.0 -163000.0 -1.71 -2.6796 -0.9951 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P22 compound treatment 353050.0 -112000.0 -1.14 406480.0 -46800.0 -0.49 -1.1527 -0.9292 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P23 compound treatment 347010.0 -118000.0 -1.2 360510.0 -92800.0 -0.97 -1.5367 -0.9945 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2102 P24 compound treatment 355910.0 -109000.0 -1.11 368320.0 -85000.0 -0.89 -1.4149 -0.994 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A01 compound treatment 333360.0 -123000.0 -1.25 369720.0 -56800.0 -0.6 -1.3077 -0.9421 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A02 compound treatment 481980.0 25200.0 0.26 405000.0 -21600.0 -0.23 0.0216 0.0631 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A03 compound treatment 413330.0 -43400.0 -0.44 333280.0 -93300.0 -0.98 -1.0031 -0.9354 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A04 compound treatment 397810.0 -58900.0 -0.6 338240.0 -88300.0 -0.93 -1.0778 -0.9778 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A05 compound treatment 351250.0 -105000.0 -1.07 366210.0 -60400.0 -0.63 -1.2052 -0.9683 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A06 compound treatment 308500.0 -148000.0 -1.51 329050.0 -97500.0 -1.02 -1.7877 -0.9821 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A07 compound treatment 381080.0 -75700.0 -0.77 329380.0 -97200.0 -1.02 -1.2637 -0.9904 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A08 compound treatment 336190.0 -121000.0 -1.23 279160.0 -147000.0 -1.54 -1.9583 -0.9934 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A09 compound treatment 438900.0 -17800.0 -0.18 292050.0 -135000.0 -1.41 -1.1248 -0.7916 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A10 compound treatment 372370.0 -84400.0 -0.86 445150.0 18600.0 0.19 -0.4686 -0.5329 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A11 compound treatment 340640.0 -116000.0 -1.18 338040.0 -88500.0 -0.93 -1.4901 -0.9929 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A12 compound treatment 425010.0 -31700.0 -0.32 291850.0 -135000.0 -1.41 -1.2261 -0.8469 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A13 mock treatment 416160.0 -40600.0 -0.41 362240.0 -64300.0 -0.67 -0.7682 -0.9722 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A14 mock treatment 366560.0 -90200.0 -0.92 411050.0 -15500.0 -0.16 -0.763 -0.8197 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A15 compound treatment 409840.0 -46900.0 -0.48 340160.0 -86400.0 -0.91 -0.9772 -0.9551 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A16 compound treatment 312510.0 -144000.0 -1.47 375000.0 -51600.0 -0.54 -1.4184 -0.908 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A17 compound treatment 451930.0 -4820.0 -0.05 342300.0 -84300.0 -0.88 -0.6589 -0.7452 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A18 compound treatment 452440.0 -4310.0 -0.04 405920.0 -20600.0 -0.22 -0.1839 -0.8333 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A19 compound treatment 435240.0 -21500.0 -0.22 379810.0 -46800.0 -0.49 -0.5009 -0.9339 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A20 compound treatment 373680.0 -83100.0 -0.84 375570.0 -51000.0 -0.53 -0.9747 -0.9756 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A21 compound treatment 372130.0 -84600.0 -0.86 307260.0 -119000.0 -1.25 -1.4919 -0.9833 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A22 compound treatment 427230.0 -29500.0 -0.3 393720.0 -32800.0 -0.34 -0.4554 -0.9977 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A23 compound treatment 393010.0 -63700.0 -0.65 424230.0 -2330.0 -0.02 -0.4753 -0.7332 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 A24 compound treatment 489240.0 32500.0 0.33 421210.0 -5350.0 -0.06 0.1938 0.5788 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B01 compound treatment 442200.0 -14500.0 -0.15 430640.0 4080.0 0.04 -0.0743 -0.4829 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B02 compound treatment 448850.0 -7900.0 -0.08 418300.0 -8260.0 -0.09 -0.1179 -0.9993 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B03 compound treatment 384720.0 -72000.0 -0.73 415010.0 -11600.0 -0.12 -0.6031 -0.813 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B04 compound treatment 463620.0 6870.0 0.07 376810.0 -49800.0 -0.52 -0.3192 -0.6069 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B05 compound treatment 552350.0 95600.0 0.97 467690.0 41100.0 0.43 0.9917 0.9331 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B06 compound treatment 416890.0 -39900.0 -0.41 411280.0 -15300.0 -0.16 -0.3996 -0.9175 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B07 compound treatment 471160.0 14400.0 0.15 433250.0 6690.0 0.07 0.1531 0.9431 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B08 compound treatment 518270.0 61500.0 0.63 450170.0 23600.0 0.25 0.617 0.9177 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B09 compound treatment 366400.0 -90300.0 -0.92 428900.0 2340.0 0.02 -0.6319 -0.688 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B10 compound treatment 484830.0 28100.0 0.29 417060.0 -9500.0 -0.1 0.1314 0.4348 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B11 compound treatment 397630.0 -59100.0 -0.6 340520.0 -86000.0 -0.9 -1.0622 -0.9805 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B12 compound treatment 404180.0 -52600.0 -0.53 381760.0 -44800.0 -0.47 -0.7096 -0.9979 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B13 mock treatment 440350.0 -16400.0 -0.17 456960.0 30400.0 0.32 0.1074 0.2988 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B14 mock treatment 484030.0 27300.0 0.28 451520.0 25000.0 0.26 0.381 0.9996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B15 compound treatment 388880.0 -67900.0 -0.69 406880.0 -19700.0 -0.21 -0.6335 -0.88 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B16 compound treatment 445810.0 -10900.0 -0.11 359540.0 -67000.0 -0.7 -0.5751 -0.809 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B17 compound treatment 518080.0 61300.0 0.62 377320.0 -49200.0 -0.52 0.0759 0.0938 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B18 compound treatment 479710.0 23000.0 0.23 402250.0 -24300.0 -0.25 -0.0151 -0.0437 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B19 compound treatment 405990.0 -50800.0 -0.52 403630.0 -22900.0 -0.24 -0.5346 -0.9395 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B20 compound treatment 443140.0 -13600.0 -0.14 423370.0 -3190.0 -0.03 -0.1214 -0.8535 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B21 compound treatment 376760.0 -80000.0 -0.81 403880.0 -22700.0 -0.24 -0.7428 -0.8771 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B22 compound treatment 346400.0 -110000.0 -1.12 357330.0 -69200.0 -0.73 -1.3058 -0.9778 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B23 compound treatment 509050.0 52300.0 0.53 447330.0 20800.0 0.22 0.5297 0.9223 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 B24 compound treatment 397880.0 -58900.0 -0.6 364270.0 -62300.0 -0.65 -0.8845 -0.9991 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C01 compound treatment 310560.0 -146000.0 -1.49 341870.0 -84700.0 -0.89 -1.6779 -0.9697 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C02 compound treatment 326600.0 -130000.0 -1.32 330500.0 -96100.0 -1.01 -1.6469 -0.9909 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C03 compound treatment 335640.0 -121000.0 -1.23 354370.0 -72200.0 -0.76 -1.4051 -0.9727 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C04 compound treatment 460020.0 3270.0 0.03 321510.0 -105000.0 -1.1 -0.7548 -0.6854 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C05 compound treatment 312580.0 -144000.0 -1.47 341410.0 -85200.0 -0.89 -1.6668 -0.9717 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C06 compound treatment 331200.0 -126000.0 -1.28 330330.0 -96200.0 -1.01 -1.6151 -0.9932 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C07 compound treatment 343460.0 -113000.0 -1.15 306920.0 -120000.0 -1.25 -1.7004 -0.9991 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C08 compound treatment 415700.0 -41000.0 -0.42 374810.0 -51800.0 -0.54 -0.6784 -0.9916 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C09 compound treatment 422780.0 -34000.0 -0.35 380680.0 -45900.0 -0.48 -0.584 -0.9868 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C10 compound treatment 344640.0 -112000.0 -1.14 342740.0 -83800.0 -0.88 -1.4266 -0.9917 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C11 mock treatment 327400.0 -129000.0 -1.31 410360.0 -16200.0 -0.17 -1.0495 -0.7918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C12 mock treatment 428480.0 -28300.0 -0.29 433640.0 7080.0 0.07 -0.1507 -0.5079 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C13 compound treatment 385850.0 -70900.0 -0.72 374500.0 -52100.0 -0.55 -0.8951 -0.9906 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C14 compound treatment 240840.0 -216000.0 -2.19 232320.0 -194000.0 -2.04 -2.9905 -0.9993 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C15 mock treatment 383160.0 -73600.0 -0.75 407240.0 -19300.0 -0.2 -0.6719 -0.8673 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C16 mock treatment 417190.0 -39600.0 -0.4 373440.0 -53100.0 -0.56 -0.6778 -0.9872 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C17 compound treatment 379150.0 -77600.0 -0.79 366320.0 -60200.0 -0.63 -1.0039 -0.9939 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C18 compound treatment 236870.0 -220000.0 -2.23 201810.0 -225000.0 -2.35 -3.2451 -0.9997 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C19 compound treatment 374720.0 -82000.0 -0.83 377530.0 -49000.0 -0.51 -0.9527 -0.973 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C20 compound treatment 461050.0 4300.0 0.04 381940.0 -44600.0 -0.47 -0.2997 -0.6382 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C21 compound treatment 345760.0 -111000.0 -1.13 345490.0 -81100.0 -0.85 -1.3981 -0.9902 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C22 compound treatment 387690.0 -69100.0 -0.7 359620.0 -66900.0 -0.7 -0.9922 -1.0 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C23 compound treatment 391060.0 -65700.0 -0.67 374590.0 -52000.0 -0.54 -0.857 -0.9949 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 C24 compound treatment 393070.0 -63700.0 -0.65 361640.0 -64900.0 -0.68 -0.9385 -0.9997 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D01 compound treatment 470560.0 13800.0 0.14 500900.0 74300.0 0.78 0.65 0.8213 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D02 compound treatment 376500.0 -80200.0 -0.82 453030.0 26500.0 0.28 -0.3805 -0.4418 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D03 compound treatment 388930.0 -67800.0 -0.69 415120.0 -11400.0 -0.12 -0.5721 -0.8178 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D04 compound treatment 409500.0 -47200.0 -0.48 385000.0 -41600.0 -0.44 -0.6474 -0.9988 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D05 compound treatment 422530.0 -34200.0 -0.35 400960.0 -25600.0 -0.27 -0.4355 -0.9918 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D06 compound treatment 319170.0 -138000.0 -1.4 302950.0 -124000.0 -1.3 -1.9044 -0.9993 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D07 compound treatment 444800.0 -11900.0 -0.12 409300.0 -17300.0 -0.18 -0.2137 -0.9812 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D08 compound treatment 542250.0 85500.0 0.87 484880.0 58300.0 0.61 1.0465 0.9852 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D09 compound treatment 416060.0 -40700.0 -0.41 402960.0 -23600.0 -0.25 -0.4672 -0.9698 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D10 compound treatment 501620.0 44900.0 0.46 400640.0 -25900.0 -0.27 0.1304 0.2457 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D11 mock treatment 472980.0 16200.0 0.16 351410.0 -75200.0 -0.79 -0.4401 -0.5471 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D12 mock treatment 440820.0 -15900.0 -0.16 333090.0 -93500.0 -0.98 -0.8069 -0.8129 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D13 compound treatment 396480.0 -60300.0 -0.61 388340.0 -38200.0 -0.4 -0.7162 -0.9788 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D14 compound treatment 449050.0 -7700.0 -0.08 292490.0 -134000.0 -1.4 -1.0486 -0.7453 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D15 mock treatment 394890.0 -61900.0 -0.63 370270.0 -56300.0 -0.59 -0.8615 -0.9995 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D16 mock treatment 519680.0 62900.0 0.64 367860.0 -58700.0 -0.62 0.0173 0.0195 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D17 compound treatment 464230.0 7480.0 0.08 436500.0 9940.0 0.1 0.1274 0.9881 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D18 compound treatment 427250.0 -29500.0 -0.3 356130.0 -70400.0 -0.74 -0.7338 -0.9212 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D19 compound treatment 455920.0 -827.0 -0.01 393640.0 -32900.0 -0.34 -0.2498 -0.7241 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D20 compound treatment 373760.0 -83000.0 -0.84 375570.0 -51000.0 -0.53 -0.9741 -0.9757 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D21 compound treatment 444810.0 -11900.0 -0.12 446670.0 20100.0 0.21 0.0632 0.26 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D22 compound treatment 425000.0 -31700.0 -0.32 381000.0 -45600.0 -0.48 -0.5657 -0.9818 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D23 compound treatment 440650.0 -16100.0 -0.16 422420.0 -4140.0 -0.04 -0.1463 -0.8647 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 D24 compound treatment 423800.0 -32900.0 -0.33 381230.0 -45300.0 -0.47 -0.5726 -0.9854 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E01 mock treatment 390920.0 -65800.0 -0.67 515320.0 88800.0 0.93 0.1846 0.1611 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E02 mock treatment 440670.0 -16100.0 -0.16 475650.0 49100.0 0.51 0.2482 0.4599 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E03 compound treatment 349490.0 -107000.0 -1.09 326400.0 -100000.0 -1.05 -1.5128 -0.9998 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E04 compound treatment 404730.0 -52000.0 -0.53 342720.0 -83800.0 -0.88 -0.9949 -0.9705 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E05 compound treatment 343390.0 -113000.0 -1.15 333390.0 -93200.0 -0.98 -1.5048 -0.9966 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E06 compound treatment 451520.0 -5230.0 -0.05 413500.0 -13100.0 -0.14 -0.1343 -0.9151 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E07 compound treatment 500270.0 43500.0 0.44 417570.0 -8990.0 -0.09 0.2461 0.5443 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E08 compound treatment 483630.0 26900.0 0.27 350240.0 -76300.0 -0.8 -0.3723 -0.4405 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E09 mock treatment 448450.0 -8300.0 -0.08 379540.0 -47000.0 -0.49 -0.408 -0.8163 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E10 mock treatment 560490.0 104000.0 1.05 399900.0 -26700.0 -0.28 0.5479 0.5024 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E11 compound treatment 503870.0 47100.0 0.48 453920.0 27400.0 0.29 0.5413 0.9699 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E12 compound treatment 421820.0 -34900.0 -0.35 339370.0 -87200.0 -0.91 -0.8969 -0.9152 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E13 compound treatment 470240.0 13500.0 0.14 462480.0 35900.0 0.38 0.3631 0.9064 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E14 compound treatment 450930.0 -5820.0 -0.06 372090.0 -54500.0 -0.57 -0.4454 -0.7762 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E15 compound treatment 412370.0 -44400.0 -0.45 408880.0 -17700.0 -0.19 -0.4499 -0.9228 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E16 compound treatment 292870.0 -164000.0 -1.67 180970.0 -246000.0 -2.57 -2.9971 -0.9778 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E17 mock treatment 436410.0 -20300.0 -0.21 433400.0 6840.0 0.07 -0.0955 -0.4364 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E18 mock treatment 465140.0 8390.0 0.09 421510.0 -5050.0 -0.05 0.0229 0.2281 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E19 compound treatment 403430.0 -53300.0 -0.54 382840.0 -43700.0 -0.46 -0.707 -0.9965 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E20 compound treatment 439810.0 -16900.0 -0.17 383130.0 -43400.0 -0.46 -0.4435 -0.9115 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E21 compound treatment 384320.0 -72400.0 -0.74 372590.0 -54000.0 -0.57 -0.9203 -0.9915 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E22 compound treatment 455490.0 -1260.0 -0.01 409150.0 -17400.0 -0.18 -0.138 -0.7548 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E23 compound treatment 413000.0 -43700.0 -0.44 392580.0 -34000.0 -0.36 -0.5661 -0.9939 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 E24 compound treatment 320050.0 -137000.0 -1.39 305790.0 -121000.0 -1.27 -1.877 -0.9989 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F01 mock treatment 462830.0 6080.0 0.06 393180.0 -33400.0 -0.35 -0.2036 -0.5732 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F02 mock treatment 458240.0 1490.0 0.02 498800.0 72200.0 0.76 0.5459 0.7211 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F03 compound treatment 499430.0 42700.0 0.43 424930.0 -1630.0 -0.02 0.2946 0.6787 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F04 compound treatment 362800.0 -93900.0 -0.95 287910.0 -139000.0 -1.45 -1.7023 -0.9793 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F05 compound treatment 374660.0 -82100.0 -0.83 381280.0 -45300.0 -0.47 -0.9253 -0.9642 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F06 compound treatment 517290.0 60500.0 0.62 370680.0 -55900.0 -0.59 0.021 0.0248 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F07 compound treatment 475890.0 19100.0 0.19 396480.0 -30100.0 -0.32 -0.0853 -0.2303 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F08 compound treatment 515290.0 58500.0 0.59 457280.0 30700.0 0.32 0.6483 0.9584 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F09 mock treatment 437920.0 -18800.0 -0.19 393120.0 -33400.0 -0.35 -0.383 -0.9595 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F10 mock treatment 513490.0 56700.0 0.58 452160.0 25600.0 0.27 0.5974 0.9394 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F11 compound treatment 370790.0 -86000.0 -0.87 305640.0 -121000.0 -1.27 -1.5135 -0.9835 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F12 compound treatment 492280.0 35500.0 0.36 379850.0 -46700.0 -0.49 -0.0907 -0.1492 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F13 compound treatment 399160.0 -57600.0 -0.59 363270.0 -63300.0 -0.66 -0.8827 -0.9981 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F14 compound treatment 413520.0 -43200.0 -0.44 395000.0 -31600.0 -0.33 -0.5444 -0.9902 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F15 compound treatment 439220.0 -17500.0 -0.18 403640.0 -22900.0 -0.24 -0.2958 -0.9892 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F16 compound treatment 336010.0 -121000.0 -1.23 316510.0 -110000.0 -1.15 -1.6829 -0.9995 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F17 mock treatment 415000.0 -41700.0 -0.42 403940.0 -22600.0 -0.24 -0.4676 -0.9622 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F18 mock treatment 472320.0 15600.0 0.16 433980.0 7420.0 0.08 0.1669 0.9464 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F19 compound treatment 392480.0 -64300.0 -0.65 410560.0 -16000.0 -0.17 -0.5803 -0.8607 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F20 compound treatment 378650.0 -78100.0 -0.79 381120.0 -45400.0 -0.48 -0.8978 -0.9701 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F21 compound treatment 456850.0 103.0 0.0 404870.0 -21700.0 -0.23 -0.16 -0.7038 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F22 compound treatment 428390.0 -28400.0 -0.29 355140.0 -71400.0 -0.75 -0.7329 -0.914 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F23 compound treatment 447420.0 -9330.0 -0.09 428550.0 1990.0 0.02 -0.0523 -0.5387 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 F24 compound treatment 400410.0 -56300.0 -0.57 376240.0 -50300.0 -0.53 -0.7776 -0.9992 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G01 compound treatment 429810.0 -26900.0 -0.27 342190.0 -84400.0 -0.88 -0.8186 -0.8846 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G02 compound treatment 227230.0 -230000.0 -2.33 169020.0 -258000.0 -2.7 -3.5573 -0.9974 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G03 mock treatment 360080.0 -96700.0 -0.98 332000.0 -94600.0 -0.99 -1.3952 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G04 mock treatment 371370.0 -85400.0 -0.87 382080.0 -44500.0 -0.47 -0.943 -0.9575 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G05 compound treatment 370480.0 -86300.0 -0.88 361890.0 -64700.0 -0.68 -1.099 -0.9919 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G06 compound treatment 408090.0 -48700.0 -0.49 463840.0 37300.0 0.39 -0.0734 -0.1166 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G07 compound treatment 412680.0 -44100.0 -0.45 366610.0 -60000.0 -0.63 -0.7608 -0.9862 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G08 compound treatment 373930.0 -82800.0 -0.84 386000.0 -40600.0 -0.42 -0.8956 -0.9499 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G09 compound treatment 459740.0 2990.0 0.03 454750.0 28200.0 0.3 0.2304 0.7758 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G10 compound treatment 436250.0 -20500.0 -0.21 441400.0 14800.0 0.16 -0.0373 -0.1437 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G11 compound treatment 345980.0 -111000.0 -1.13 392230.0 -34300.0 -0.36 -1.0503 -0.8888 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G12 compound treatment 343680.0 -113000.0 -1.15 211630.0 -215000.0 -2.25 -2.4048 -0.9512 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G13 compound treatment 361510.0 -95200.0 -0.97 374340.0 -52200.0 -0.55 -1.0712 -0.9635 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G14 compound treatment 413300.0 -43400.0 -0.44 415840.0 -10700.0 -0.11 -0.3916 -0.8596 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G15 compound treatment 396740.0 -60000.0 -0.61 453940.0 27400.0 0.29 -0.2283 -0.3388 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G16 compound treatment 448840.0 -7910.0 -0.08 335110.0 -91500.0 -0.96 -0.7344 -0.7637 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G17 compound treatment 409780.0 -47000.0 -0.48 336080.0 -90500.0 -0.95 -1.0078 -0.9496 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G18 compound treatment 400330.0 -56400.0 -0.57 394250.0 -32300.0 -0.34 -0.6448 -0.9684 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G19 mock treatment 478370.0 21600.0 0.22 499860.0 73300.0 0.77 0.6984 0.8743 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G20 mock treatment 431250.0 -25500.0 -0.26 417920.0 -8640.0 -0.09 -0.2472 -0.9008 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G21 compound treatment 449690.0 -7060.0 -0.07 353170.0 -73400.0 -0.77 -0.5944 -0.7697 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G22 compound treatment 393310.0 -63400.0 -0.64 336900.0 -89700.0 -0.94 -1.1201 -0.9831 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G23 compound treatment 445130.0 -11600.0 -0.12 386880.0 -39700.0 -0.42 -0.3775 -0.8734 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 G24 compound treatment 373230.0 -83500.0 -0.85 309120.0 -117000.0 -1.23 -1.4702 -0.9836 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H01 compound treatment 357620.0 -99100.0 -1.01 439850.0 13300.0 0.14 -0.6138 -0.6036 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H02 compound treatment 456920.0 173.0 0.0 334980.0 -91600.0 -0.96 -0.6773 -0.7058 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H03 mock treatment 460640.0 3890.0 0.04 355330.0 -71200.0 -0.75 -0.4998 -0.6687 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H04 mock treatment 483890.0 27100.0 0.28 378360.0 -48200.0 -0.51 -0.1621 -0.2816 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H05 compound treatment 418410.0 -38300.0 -0.39 388860.0 -37700.0 -0.4 -0.5548 -1.0 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H06 compound treatment 548800.0 92100.0 0.94 288730.0 -138000.0 -1.44 -0.3597 -0.209 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H07 compound treatment 516000.0 59300.0 0.6 404020.0 -22500.0 -0.24 0.2588 0.4001 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H08 compound treatment 508240.0 51500.0 0.52 408800.0 -17800.0 -0.19 0.2384 0.4293 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H09 compound treatment 416110.0 -40600.0 -0.41 369150.0 -57400.0 -0.6 -0.7173 -0.9832 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H10 compound treatment 441620.0 -15100.0 -0.15 425760.0 -801.0 -0.01 -0.1146 -0.7446 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H11 compound treatment 441670.0 -15100.0 -0.15 333540.0 -93000.0 -0.97 -0.7975 -0.8083 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H12 compound treatment 466250.0 9500.0 0.1 476510.0 49900.0 0.52 0.4383 0.8237 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H13 compound treatment 412930.0 -43800.0 -0.45 411470.0 -15100.0 -0.16 -0.4267 -0.903 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H14 compound treatment 392670.0 -64100.0 -0.65 401030.0 -25500.0 -0.27 -0.6496 -0.9228 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H15 compound treatment 414500.0 -42200.0 -0.43 350480.0 -76100.0 -0.8 -0.8672 -0.9579 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H16 compound treatment 456090.0 -657.0 -0.01 343290.0 -83300.0 -0.87 -0.6217 -0.7125 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H17 compound treatment 431700.0 -25000.0 -0.25 327680.0 -98900.0 -1.04 -0.9126 -0.8554 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H18 compound treatment 485920.0 29200.0 0.3 409920.0 -16600.0 -0.17 0.0863 0.251 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H19 mock treatment 485550.0 28800.0 0.29 480040.0 53500.0 0.56 0.6032 0.9541 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H20 mock treatment 486950.0 30200.0 0.31 368230.0 -58300.0 -0.61 -0.2151 -0.3146 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H21 compound treatment 476690.0 19900.0 0.2 404070.0 -22500.0 -0.24 -0.0233 -0.075 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H22 compound treatment 337250.0 -119000.0 -1.21 379200.0 -47400.0 -0.5 -1.2096 -0.922 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H23 compound treatment 426320.0 -30400.0 -0.31 449250.0 22700.0 0.24 -0.0505 -0.1296 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 H24 compound treatment 450450.0 -6300.0 -0.06 424290.0 -2270.0 -0.02 -0.0621 -0.9092 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I01 compound treatment 369780.0 -87000.0 -0.88 319960.0 -107000.0 -1.12 -1.4147 -0.9933 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I02 compound treatment 433230.0 -23500.0 -0.24 367370.0 -59200.0 -0.62 -0.6075 -0.9141 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I03 compound treatment 370780.0 -86000.0 -0.87 312020.0 -115000.0 -1.2 -1.4663 -0.9878 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I04 compound treatment 395570.0 -61200.0 -0.62 449670.0 23100.0 0.24 -0.2684 -0.4023 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I05 mock treatment 400060.0 -56700.0 -0.58 401630.0 -24900.0 -0.26 -0.592 -0.936 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I06 mock treatment 426250.0 -30500.0 -0.31 317990.0 -109000.0 -1.14 -1.0235 -0.8681 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I07 compound treatment 427810.0 -28900.0 -0.29 340020.0 -86500.0 -0.91 -0.8491 -0.8908 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I08 compound treatment 410720.0 -46000.0 -0.47 383220.0 -43300.0 -0.45 -0.6518 -0.9999 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I09 compound treatment 413850.0 -42900.0 -0.44 415440.0 -11100.0 -0.12 -0.3906 -0.8657 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I10 compound treatment 392130.0 -64600.0 -0.66 355090.0 -71500.0 -0.75 -0.9938 -0.9979 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I11 compound treatment 432840.0 -23900.0 -0.24 357180.0 -69400.0 -0.73 -0.6858 -0.8948 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I12 compound treatment 400650.0 -56100.0 -0.57 351450.0 -75100.0 -0.79 -0.9596 -0.9875 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I13 compound treatment 505410.0 48700.0 0.49 436450.0 9890.0 0.1 0.4229 0.8371 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I14 compound treatment 522630.0 65900.0 0.67 411360.0 -15200.0 -0.16 0.3608 0.5243 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I15 compound treatment 471480.0 14700.0 0.15 415390.0 -11200.0 -0.12 0.0231 0.1216 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I16 compound treatment 551940.0 95200.0 0.97 468920.0 42400.0 0.44 0.9979 0.9376 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I17 compound treatment 425510.0 -31200.0 -0.32 462920.0 36400.0 0.38 0.0449 0.0906 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I18 compound treatment 196760.0 -260000.0 -2.64 191170.0 -235000.0 -2.47 -3.6121 -0.9994 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I19 compound treatment 494600.0 37900.0 0.38 384100.0 -42500.0 -0.44 -0.0426 -0.0724 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I20 compound treatment 444050.0 -12700.0 -0.13 415070.0 -11500.0 -0.12 -0.1764 -0.9994 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I21 mock treatment 411280.0 -45500.0 -0.46 396960.0 -29600.0 -0.31 -0.546 -0.9812 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I22 mock treatment 498050.0 41300.0 0.42 424060.0 -2500.0 -0.03 0.2783 0.6617 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I23 compound treatment 347560.0 -109000.0 -1.11 349760.0 -76800.0 -0.8 -1.3536 -0.9876 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 I24 compound treatment 381090.0 -75700.0 -0.77 364430.0 -62100.0 -0.65 -1.004 -0.9966 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J01 compound treatment 447600.0 -9150.0 -0.09 413990.0 -12600.0 -0.13 -0.1589 -0.9854 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J02 compound treatment 351140.0 -106000.0 -1.07 339360.0 -87200.0 -0.91 -1.4049 -0.9968 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J03 compound treatment 407370.0 -49400.0 -0.5 398150.0 -28400.0 -0.3 -0.5653 -0.9689 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J04 compound treatment 396520.0 -60200.0 -0.61 373050.0 -53500.0 -0.56 -0.8292 -0.999 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J05 mock treatment 464800.0 8050.0 0.08 353990.0 -72600.0 -0.76 -0.4798 -0.6274 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J06 mock treatment 517960.0 61200.0 0.62 411100.0 -15500.0 -0.16 0.3253 0.5061 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J07 compound treatment 448530.0 -8220.0 -0.08 457240.0 30700.0 0.32 0.1682 0.5066 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J08 compound treatment 366470.0 -90300.0 -0.92 328830.0 -97700.0 -1.02 -1.3728 -0.9985 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J09 compound treatment 413250.0 -43500.0 -0.44 390470.0 -36100.0 -0.38 -0.5799 -0.997 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J10 compound treatment 333780.0 -123000.0 -1.25 317120.0 -109000.0 -1.15 -1.6944 -0.9991 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J11 compound treatment 405340.0 -51400.0 -0.52 404650.0 -21900.0 -0.23 -0.5317 -0.9318 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J12 compound treatment 372190.0 -84600.0 -0.86 370560.0 -56000.0 -0.59 -1.0225 -0.9827 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J13 compound treatment 454580.0 -2170.0 -0.02 496110.0 69500.0 0.73 0.4997 0.6854 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J14 compound treatment 295440.0 -161000.0 -1.64 208090.0 -218000.0 -2.29 -2.7777 -0.9866 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J15 compound treatment 456420.0 -327.0 0.0 446160.0 19600.0 0.21 0.1429 0.6956 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J16 compound treatment 388520.0 -68200.0 -0.69 281200.0 -145000.0 -1.52 -1.5672 -0.9365 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J17 compound treatment 424430.0 -32300.0 -0.33 443520.0 17000.0 0.18 -0.1066 -0.2854 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J18 compound treatment 344380.0 -112000.0 -1.14 295520.0 -131000.0 -1.37 -1.7783 -0.9958 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J19 compound treatment 480080.0 23300.0 0.24 379080.0 -47500.0 -0.5 -0.1841 -0.3341 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J20 compound treatment 453920.0 -2830.0 -0.03 370090.0 -56500.0 -0.59 -0.4387 -0.7406 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J21 mock treatment 435770.0 -21000.0 -0.21 433550.0 6990.0 0.07 -0.099 -0.439 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J22 mock treatment 506530.0 49800.0 0.51 380400.0 -46200.0 -0.48 0.0157 0.0225 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J23 compound treatment 434980.0 -21800.0 -0.22 432230.0 5670.0 0.06 -0.1144 -0.4995 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 J24 compound treatment 429620.0 -27100.0 -0.28 380410.0 -46200.0 -0.48 -0.5368 -0.9645 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K01 compound treatment 316750.0 -140000.0 -1.42 409780.0 -16800.0 -0.18 -1.1303 -0.7885 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K02 compound treatment 411440.0 -45300.0 -0.46 335610.0 -91000.0 -0.95 -0.9994 -0.9443 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K03 compound treatment 323530.0 -133000.0 -1.35 329470.0 -97100.0 -1.02 -1.6766 -0.9901 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K04 compound treatment 428410.0 -28300.0 -0.29 442170.0 15600.0 0.16 -0.088 -0.2657 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K05 compound treatment 469510.0 12800.0 0.13 333330.0 -93200.0 -0.98 -0.599 -0.6079 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K06 compound treatment 342010.0 -115000.0 -1.17 409880.0 -16700.0 -0.17 -0.948 -0.8041 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K07 mock treatment 476880.0 20100.0 0.2 445650.0 19100.0 0.2 0.2861 0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K08 mock treatment 370210.0 -86500.0 -0.88 518830.0 92300.0 0.97 0.0618 0.0473 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K09 compound treatment 456430.0 -317.0 0.0 390010.0 -36600.0 -0.38 -0.2731 -0.713 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K10 compound treatment 193680.0 -263000.0 -2.67 165440.0 -261000.0 -2.74 -3.8249 -0.9999 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K11 compound treatment 465530.0 8780.0 0.09 373030.0 -53500.0 -0.56 -0.3335 -0.5872 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K12 compound treatment 381760.0 -75000.0 -0.76 361890.0 -64700.0 -0.68 -1.018 -0.9983 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K13 compound treatment 425600.0 -31100.0 -0.32 443810.0 17200.0 0.18 -0.096 -0.2634 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K14 compound treatment 524290.0 67500.0 0.69 452750.0 26200.0 0.27 0.6794 0.9191 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K15 mock treatment 509330.0 52600.0 0.53 501690.0 75100.0 0.79 0.9345 0.9822 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K16 mock treatment 487580.0 30800.0 0.31 542400.0 116000.0 1.21 1.0798 0.8614 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K17 compound treatment 438160.0 -18600.0 -0.19 447950.0 21400.0 0.22 0.0249 0.085 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K18 compound treatment 418940.0 -37800.0 -0.38 459920.0 33400.0 0.35 -0.0245 -0.0472 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K19 compound treatment 425760.0 -31000.0 -0.31 350160.0 -76400.0 -0.8 -0.7887 -0.9169 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K20 compound treatment 450130.0 -6620.0 -0.07 466080.0 39500.0 0.41 0.2452 0.5846 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K21 compound treatment 367300.0 -89400.0 -0.91 333300.0 -93300.0 -0.98 -1.3337 -0.9993 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K22 compound treatment 487890.0 31100.0 0.32 373630.0 -52900.0 -0.55 -0.1684 -0.2637 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K23 mock treatment 478930.0 22200.0 0.23 403110.0 -23500.0 -0.25 -0.0143 -0.043 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 K24 mock treatment 388230.0 -68500.0 -0.7 396120.0 -30400.0 -0.32 -0.7179 -0.9373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L01 compound treatment 424820.0 -31900.0 -0.32 463050.0 36500.0 0.38 0.0409 0.0816 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L02 compound treatment 546610.0 89900.0 0.91 403040.0 -23500.0 -0.25 0.4715 0.4985 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L03 compound treatment 408860.0 -47900.0 -0.49 402340.0 -24200.0 -0.25 -0.5235 -0.9539 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L04 compound treatment 340600.0 -116000.0 -1.18 407110.0 -19500.0 -0.2 -0.9787 -0.8171 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L05 compound treatment 547810.0 91100.0 0.93 480740.0 54200.0 0.57 1.0558 0.9725 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L06 compound treatment 353690.0 -103000.0 -1.05 419520.0 -7040.0 -0.07 -0.7927 -0.755 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L07 mock treatment 484770.0 28000.0 0.28 394240.0 -32300.0 -0.34 -0.0381 -0.0861 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L08 mock treatment 419240.0 -37500.0 -0.38 433410.0 6850.0 0.07 -0.2188 -0.5641 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L09 compound treatment 491520.0 34800.0 0.35 428000.0 1440.0 0.02 0.2605 0.7366 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L10 compound treatment 413280.0 -43500.0 -0.44 382670.0 -43900.0 -0.46 -0.6375 -0.9998 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L11 compound treatment 438180.0 -18600.0 -0.19 490080.0 63500.0 0.67 0.3372 0.4874 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L12 compound treatment 452130.0 -4620.0 -0.05 410720.0 -15800.0 -0.17 -0.1505 -0.8728 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L13 compound treatment 496480.0 39700.0 0.4 458530.0 32000.0 0.33 0.5224 0.9957 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L14 compound treatment 402810.0 -53900.0 -0.55 351000.0 -75600.0 -0.79 -0.9474 -0.9839 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L15 mock treatment 508860.0 52100.0 0.53 424050.0 -2510.0 -0.03 0.3559 0.6712 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L16 mock treatment 481120.0 24400.0 0.25 416260.0 -10300.0 -0.11 0.0988 0.3658 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L17 compound treatment 465640.0 8890.0 0.09 431470.0 4910.0 0.05 0.1003 0.9643 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L18 compound treatment 436160.0 -20600.0 -0.21 370530.0 -56000.0 -0.59 -0.563 -0.9034 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L19 compound treatment 473050.0 16300.0 0.17 451710.0 25100.0 0.26 0.3035 0.975 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L20 compound treatment 353320.0 -103000.0 -1.05 312920.0 -114000.0 -1.19 -1.5851 -0.9981 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L21 compound treatment 406650.0 -50100.0 -0.51 409200.0 -17400.0 -0.18 -0.4886 -0.9038 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L22 compound treatment 294080.0 -163000.0 -1.65 269000.0 -158000.0 -1.65 -2.3362 -1.0 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L23 mock treatment 489560.0 32800.0 0.33 468960.0 42400.0 0.44 0.5499 0.99 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 L24 mock treatment 463470.0 6720.0 0.07 400320.0 -26200.0 -0.27 -0.1461 -0.5157 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M01 compound treatment 359570.0 -97200.0 -0.99 335580.0 -91000.0 -0.95 -1.3723 -0.9998 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M02 compound treatment 459640.0 2890.0 0.03 410770.0 -15800.0 -0.17 -0.0962 -0.5725 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M03 compound treatment 380580.0 -76200.0 -0.77 439840.0 13300.0 0.14 -0.4489 -0.5709 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M04 compound treatment 382840.0 -73900.0 -0.75 371850.0 -54700.0 -0.57 -0.9364 -0.9911 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M05 compound treatment 404980.0 -51800.0 -0.53 389060.0 -37500.0 -0.39 -0.6498 -0.9897 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M06 compound treatment 311900.0 -145000.0 -1.47 346430.0 -80100.0 -0.84 -1.6345 -0.9646 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M07 compound treatment 414780.0 -42000.0 -0.43 342010.0 -84600.0 -0.89 -0.928 -0.9438 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M08 compound treatment 447930.0 -8820.0 -0.09 443520.0 17000.0 0.18 0.0623 0.313 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M09 mock treatment 499910.0 43200.0 0.44 431840.0 5280.0 0.06 0.3493 0.79 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M10 mock treatment 487040.0 30300.0 0.31 428550.0 1990.0 0.02 0.2324 0.7533 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M11 compound treatment 405160.0 -51600.0 -0.52 435380.0 8820.0 0.09 -0.3053 -0.5736 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M12 compound treatment 474650.0 17900.0 0.18 467850.0 41300.0 0.43 0.4345 0.9259 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M13 mock treatment 508800.0 52100.0 0.53 483860.0 57300.0 0.6 0.7986 0.998 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M14 mock treatment 447930.0 -8820.0 -0.09 434790.0 8230.0 0.09 -0.0024 -0.0192 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M15 compound treatment 475720.0 19000.0 0.19 359890.0 -66700.0 -0.7 -0.3576 -0.4935 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M16 compound treatment 514320.0 57600.0 0.59 451460.0 24900.0 0.26 0.5982 0.9338 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M17 compound treatment 421930.0 -34800.0 -0.35 411130.0 -15400.0 -0.16 -0.3645 -0.937 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M18 compound treatment 556480.0 99700.0 1.01 474030.0 47500.0 0.5 1.0683 0.9463 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M19 mock treatment 522590.0 65800.0 0.67 447690.0 21100.0 0.22 0.6297 0.8934 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M20 compound treatment 418140.0 -38600.0 -0.39 315090.0 -111000.0 -1.17 -1.1033 -0.8955 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M21 mock treatment 505010.0 48300.0 0.49 398150.0 -28400.0 -0.3 0.1363 0.2376 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M22 compound treatment 454640.0 -2110.0 -0.02 390200.0 -36400.0 -0.38 -0.2845 -0.7457 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M23 mock treatment 483890.0 27100.0 0.28 444440.0 17900.0 0.19 0.3275 0.9822 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 M24 compound treatment 298450.0 -158000.0 -1.61 306850.0 -120000.0 -1.25 -2.0244 -0.9924 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N01 compound treatment 460480.0 3730.0 0.04 398410.0 -28200.0 -0.29 -0.1817 -0.6111 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N02 compound treatment 324450.0 -132000.0 -1.34 334800.0 -91800.0 -0.96 -1.6305 -0.9865 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N03 compound treatment 468210.0 11500.0 0.12 434620.0 8060.0 0.08 0.1421 0.9875 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N04 compound treatment 452930.0 -3820.0 -0.04 431230.0 4670.0 0.05 0.0072 0.1148 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N05 compound treatment 418490.0 -38300.0 -0.39 467480.0 40900.0 0.43 0.0283 0.0488 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N06 compound treatment 411520.0 -45200.0 -0.46 372340.0 -54200.0 -0.57 -0.7267 -0.9945 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N07 compound treatment 392430.0 -64300.0 -0.65 438630.0 12100.0 0.13 -0.3727 -0.5599 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N08 compound treatment 376210.0 -80500.0 -0.82 307880.0 -119000.0 -1.24 -1.458 -0.9794 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N09 mock treatment 373000.0 -83700.0 -0.85 446050.0 19500.0 0.2 -0.4574 -0.5226 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N10 mock treatment 445620.0 -11100.0 -0.11 418100.0 -8460.0 -0.09 -0.1426 -0.9927 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N11 compound treatment 433360.0 -23400.0 -0.24 426250.0 -311.0 0.0 -0.1704 -0.7167 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N12 compound treatment 365460.0 -91300.0 -0.93 297450.0 -129000.0 -1.35 -1.6125 -0.9831 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N13 mock treatment 407040.0 -49700.0 -0.51 480320.0 53800.0 0.56 0.0411 0.0543 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N14 mock treatment 489440.0 32700.0 0.33 522570.0 96000.0 1.01 0.9462 0.8932 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N15 compound treatment 469150.0 12400.0 0.13 451910.0 25300.0 0.27 0.2769 0.942 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N16 compound treatment 418170.0 -38600.0 -0.39 411960.0 -14600.0 -0.15 -0.3854 -0.9158 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N17 compound treatment 498720.0 42000.0 0.43 475140.0 48600.0 0.51 0.6615 0.9961 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N18 compound treatment 394130.0 -62600.0 -0.64 385720.0 -40800.0 -0.43 -0.7525 -0.9814 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N19 compound treatment 510360.0 53600.0 0.54 429800.0 3240.0 0.03 0.4092 0.7497 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N20 compound treatment 310520.0 -146000.0 -1.49 267010.0 -160000.0 -1.67 -2.2328 -0.9983 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N21 compound treatment 526830.0 70100.0 0.71 458360.0 31800.0 0.33 0.7392 0.9401 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N22 compound treatment 376550.0 -80200.0 -0.81 296750.0 -130000.0 -1.36 -1.538 -0.97 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N23 compound treatment 498040.0 41300.0 0.42 456100.0 29500.0 0.31 0.5156 0.9888 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 N24 compound treatment 279050.0 -178000.0 -1.81 300900.0 -126000.0 -1.32 -2.2079 -0.9879 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O01 mock treatment 395260.0 -61500.0 -0.62 467790.0 41200.0 0.43 -0.1364 -0.1795 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O02 compound treatment 297480.0 -159000.0 -1.62 334300.0 -92300.0 -0.97 -1.828 -0.9697 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O03 mock treatment 360240.0 -96500.0 -0.98 438520.0 12000.0 0.13 -0.6049 -0.6118 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O04 mock treatment 485360.0 28600.0 0.29 480240.0 53700.0 0.56 0.6033 0.9529 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O05 mock treatment 462140.0 5390.0 0.05 419210.0 -7350.0 -0.08 -0.0157 -0.1662 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O06 mock treatment 459840.0 3090.0 0.03 393200.0 -33400.0 -0.35 -0.2249 -0.6409 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O07 mock treatment 446280.0 -10500.0 -0.11 329230.0 -97300.0 -1.02 -0.7963 -0.7766 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O08 mock treatment 384530.0 -72200.0 -0.73 439450.0 12900.0 0.14 -0.4234 -0.5675 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O09 mock treatment 509280.0 52500.0 0.53 439810.0 13200.0 0.14 0.4756 0.8623 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O10 mock treatment 446880.0 -9870.0 -0.1 467460.0 40900.0 0.43 0.2321 0.5274 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O11 mock treatment 410560.0 -46200.0 -0.47 405810.0 -20800.0 -0.22 -0.4856 -0.9388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O12 mock treatment 485410.0 28700.0 0.29 496110.0 69500.0 0.73 0.7212 0.919 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O13 mock treatment 473370.0 16600.0 0.17 497040.0 70500.0 0.74 0.6416 0.847 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O14 mock treatment 456970.0 223.0 0.0 485490.0 58900.0 0.62 0.4382 0.7097 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O15 mock treatment 496720.0 40000.0 0.41 440170.0 13600.0 0.14 0.3881 0.9014 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O16 mock treatment 511890.0 55100.0 0.56 487100.0 60500.0 0.63 0.8448 0.9981 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O17 mock treatment 500320.0 43600.0 0.44 499090.0 72500.0 0.76 0.8505 0.9669 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O18 mock treatment 473820.0 17100.0 0.17 409230.0 -17300.0 -0.18 -0.0057 -0.0228 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O19 mock treatment 513570.0 56800.0 0.58 403840.0 -22700.0 -0.24 0.24 0.3842 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O20 mock treatment 486770.0 30000.0 0.31 389390.0 -37200.0 -0.39 -0.0597 -0.1206 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O21 mock treatment 479200.0 22500.0 0.23 507240.0 80700.0 0.85 0.7591 0.8669 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O22 mock treatment 481470.0 24700.0 0.25 410290.0 -16300.0 -0.17 0.0571 0.1881 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O23 mock treatment 442770.0 -14000.0 -0.14 436090.0 9530.0 0.1 -0.0298 -0.1718 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 O24 mock treatment 485200.0 28500.0 0.29 440000.0 13400.0 0.14 0.304 0.9453 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P01 compound treatment 340080.0 -117000.0 -1.19 416330.0 -10200.0 -0.11 -0.9141 -0.7679 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P02 compound treatment 374020.0 -82700.0 -0.84 364660.0 -61900.0 -0.65 -1.0531 -0.9918 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P03 compound treatment 438980.0 -17800.0 -0.18 387380.0 -39200.0 -0.41 -0.4179 -0.9319 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P04 compound treatment 255110.0 -202000.0 -2.05 288560.0 -138000.0 -1.45 -2.4713 -0.9854 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P05 compound treatment 370480.0 -86300.0 -0.88 416750.0 -9810.0 -0.1 -0.6926 -0.7846 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P06 compound treatment 389970.0 -66800.0 -0.68 323480.0 -103000.0 -1.08 -1.2435 -0.9749 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P07 compound treatment 374560.0 -82200.0 -0.84 319160.0 -107000.0 -1.13 -1.3863 -0.9892 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P08 compound treatment 369160.0 -87600.0 -0.89 364650.0 -61900.0 -0.65 -1.0881 -0.9879 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P09 compound treatment 352560.0 -104000.0 -1.06 332650.0 -93900.0 -0.98 -1.4444 -0.9993 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P10 compound treatment 368000.0 -88700.0 -0.9 332820.0 -93700.0 -0.98 -1.3322 -0.9991 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P11 mock treatment 430300.0 -26400.0 -0.27 419580.0 -6980.0 -0.07 -0.2418 -0.868 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P12 mock treatment 445410.0 -11300.0 -0.12 391480.0 -35100.0 -0.37 -0.3414 -0.8862 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P13 compound treatment 391680.0 -65100.0 -0.66 426290.0 -271.0 0.0 -0.4696 -0.7101 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P14 compound treatment 343700.0 -113000.0 -1.15 334190.0 -92400.0 -0.97 -1.4967 -0.9964 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P15 compound treatment 381180.0 -75600.0 -0.77 394500.0 -32100.0 -0.34 -0.7805 -0.9312 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P16 compound treatment 439360.0 -17400.0 -0.18 416670.0 -9890.0 -0.1 -0.1982 -0.9677 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P17 compound treatment 389350.0 -67400.0 -0.68 352450.0 -74100.0 -0.78 -1.0334 -0.998 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P18 compound treatment 309510.0 -147000.0 -1.5 328610.0 -98000.0 -1.03 -1.7837 -0.9831 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P19 compound treatment 382980.0 -73800.0 -0.75 380930.0 -45600.0 -0.48 -0.8681 -0.9764 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P20 compound treatment 256190.0 -201000.0 -2.04 261830.0 -165000.0 -1.73 -2.6616 -0.9966 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P21 compound treatment 378370.0 -78400.0 -0.8 378950.0 -47600.0 -0.5 -0.9159 -0.9746 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P22 compound treatment 303170.0 -154000.0 -1.56 295950.0 -131000.0 -1.37 -2.0712 -0.9979 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P23 compound treatment 433930.0 -22800.0 -0.23 406830.0 -19700.0 -0.21 -0.3101 -0.9984 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2130 P24 compound treatment 299750.0 -157000.0 -1.6 306910.0 -120000.0 -1.25 -2.0146 -0.9929 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A01 compound treatment 225390.0 -178000.0 -1.81 256640.0 -103000.0 -1.08 -2.0434 -0.9701 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A02 compound treatment 341840.0 -61300.0 -0.62 295310.0 -64700.0 -0.68 -0.9201 -0.9991 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A03 compound treatment 403480.0 330.0 0.0 332610.0 -27400.0 -0.29 -0.2008 -0.6988 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A04 compound treatment 367580.0 -35600.0 -0.36 321930.0 -38100.0 -0.4 -0.5379 -0.9988 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A05 compound treatment 329140.0 -74000.0 -0.75 282950.0 -77100.0 -0.81 -1.1029 -0.9994 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A06 compound treatment 272110.0 -131000.0 -1.33 203520.0 -157000.0 -1.64 -2.1012 -0.9947 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A07 compound treatment 296000.0 -107000.0 -1.09 268830.0 -91200.0 -0.96 -1.4457 -0.9979 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A08 compound treatment 366010.0 -37100.0 -0.38 313050.0 -47000.0 -0.49 -0.615 -0.9914 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A09 compound treatment 321680.0 -81500.0 -0.83 305460.0 -54600.0 -0.57 -0.9897 -0.9837 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A10 compound treatment 256570.0 -147000.0 -1.49 279840.0 -80200.0 -0.84 -1.6474 -0.9633 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A11 compound treatment 294150.0 -109000.0 -1.11 300960.0 -59100.0 -0.62 -1.2209 -0.9622 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A12 compound treatment 332800.0 -70300.0 -0.71 336540.0 -23500.0 -0.25 -0.6796 -0.8988 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A13 mock treatment 312400.0 -90700.0 -0.92 343850.0 -16200.0 -0.17 -0.772 -0.8233 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A14 mock treatment 378620.0 -24500.0 -0.25 363000.0 2970.0 0.03 -0.1543 -0.6142 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A15 compound treatment 353120.0 -50000.0 -0.51 358080.0 -1960.0 -0.02 -0.374 -0.735 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A16 compound treatment 377160.0 -26000.0 -0.26 422510.0 62500.0 0.65 0.2761 0.3912 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A17 compound treatment 349010.0 -54100.0 -0.55 338950.0 -21100.0 -0.22 -0.5452 -0.9197 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A18 compound treatment 365940.0 -37200.0 -0.38 362460.0 2430.0 0.03 -0.2494 -0.6581 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A19 compound treatment 303740.0 -99400.0 -1.01 353280.0 -6760.0 -0.07 -0.7644 -0.7548 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A20 compound treatment 466780.0 63600.0 0.65 350800.0 -9240.0 -0.1 0.3888 0.5947 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A21 compound treatment 342290.0 -60900.0 -0.62 293030.0 -67000.0 -0.7 -0.9337 -0.998 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A22 compound treatment 361290.0 -41900.0 -0.43 331360.0 -28700.0 -0.3 -0.5132 -0.9855 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A23 compound treatment 369130.0 -34000.0 -0.35 287220.0 -72800.0 -0.76 -0.7839 -0.9359 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 A24 compound treatment 366570.0 -36600.0 -0.37 348960.0 -11100.0 -0.12 -0.3449 -0.8857 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B01 compound treatment 439320.0 36200.0 0.37 351200.0 -8840.0 -0.09 0.1945 0.513 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B02 compound treatment 454000.0 50900.0 0.52 372840.0 12800.0 0.13 0.4603 0.8621 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B03 compound treatment 314460.0 -88700.0 -0.9 233410.0 -127000.0 -1.33 -1.5754 -0.9823 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B04 compound treatment 257920.0 -145000.0 -1.48 276800.0 -83200.0 -0.87 -1.6602 -0.9685 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B05 compound treatment 457860.0 54700.0 0.56 366900.0 6870.0 0.07 0.444 0.792 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B06 compound treatment 258760.0 -144000.0 -1.47 284160.0 -75900.0 -0.79 -1.5997 -0.9586 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B07 compound treatment 374200.0 -28900.0 -0.29 309860.0 -50200.0 -0.53 -0.5798 -0.9624 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B08 compound treatment 206480.0 -197000.0 -2.0 185490.0 -175000.0 -1.83 -2.7064 -0.999 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B09 compound treatment 450080.0 46900.0 0.48 368130.0 8100.0 0.08 0.3972 0.82 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B10 compound treatment 402090.0 -1060.0 -0.01 436800.0 76800.0 0.8 0.5611 0.6976 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B11 compound treatment 437160.0 34000.0 0.35 325940.0 -34100.0 -0.36 -0.0082 -0.0165 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B12 compound treatment 200240.0 -203000.0 -2.06 150440.0 -210000.0 -2.2 -3.0109 -0.9995 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B13 mock treatment 377230.0 -25900.0 -0.26 383780.0 23700.0 0.25 -0.0103 -0.0285 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B14 mock treatment 388840.0 -14300.0 -0.15 296120.0 -63900.0 -0.67 -0.5764 -0.8411 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B15 compound treatment 234780.0 -168000.0 -1.71 203370.0 -157000.0 -1.64 -2.3705 -0.9998 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B16 compound treatment 12330.0 -391000.0 -3.97 9730.0 -350000.0 -3.67 -5.4036 -0.9992 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B17 compound treatment 411530.0 8380.0 0.09 293970.0 -66100.0 -0.69 -0.4292 -0.6155 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B18 compound treatment 422370.0 19200.0 0.2 412650.0 52600.0 0.55 0.5279 0.9027 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B19 compound treatment 426080.0 22900.0 0.23 403810.0 43800.0 0.46 0.4891 0.9507 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B20 compound treatment 388110.0 -15000.0 -0.15 343870.0 -16200.0 -0.17 -0.2278 -0.9987 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B21 compound treatment 415970.0 12800.0 0.13 419200.0 59200.0 0.62 0.5305 0.8374 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B22 compound treatment 12820.0 -390000.0 -3.97 11520.0 -349000.0 -3.65 -5.3868 -0.9991 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B23 compound treatment 526770.0 124000.0 1.26 351530.0 -8510.0 -0.09 0.8253 0.6553 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 B24 compound treatment 130570.0 -273000.0 -2.77 100890.0 -259000.0 -2.72 -3.8786 -1.0 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C01 compound treatment 398960.0 -4190.0 -0.04 364370.0 4340.0 0.05 0.002 0.0323 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C02 compound treatment 315100.0 -88000.0 -0.89 306160.0 -53900.0 -0.56 -1.0318 -0.9753 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C03 compound treatment 317970.0 -85200.0 -0.87 324210.0 -35800.0 -0.38 -0.8775 -0.9301 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C04 compound treatment 292640.0 -111000.0 -1.12 306500.0 -53500.0 -0.56 -1.1907 -0.9485 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C05 compound treatment 72440.0 -331000.0 -3.36 41470.0 -319000.0 -3.34 -4.7365 -1.0 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C06 compound treatment 340640.0 -62500.0 -0.64 292850.0 -67200.0 -0.7 -0.9469 -0.9987 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C07 compound treatment 293180.0 -110000.0 -1.12 274340.0 -85700.0 -0.9 -1.4251 -0.9941 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C08 compound treatment 304050.0 -99100.0 -1.01 298500.0 -61500.0 -0.64 -1.168 -0.9768 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C09 compound treatment 358100.0 -45000.0 -0.46 325130.0 -34900.0 -0.37 -0.5823 -0.9938 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C10 compound treatment 311840.0 -91300.0 -0.93 290190.0 -69800.0 -0.73 -1.1736 -0.9931 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C11 mock treatment 381200.0 -21900.0 -0.22 347600.0 -12400.0 -0.13 -0.2499 -0.9672 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C12 mock treatment 378490.0 -24700.0 -0.25 340660.0 -19400.0 -0.2 -0.3207 -0.9945 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C13 compound treatment 387050.0 -16100.0 -0.16 344970.0 -15100.0 -0.16 -0.2273 -0.9998 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C14 compound treatment 365920.0 -37200.0 -0.38 343200.0 -16800.0 -0.18 -0.3922 -0.9397 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C15 mock treatment 353950.0 -49200.0 -0.5 302530.0 -57500.0 -0.6 -0.7796 -0.9957 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C16 mock treatment 395910.0 -7240.0 -0.07 307520.0 -52500.0 -0.55 -0.4411 -0.7946 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C17 compound treatment 313870.0 -89300.0 -0.91 278170.0 -81900.0 -0.86 -1.2481 -0.9996 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C18 compound treatment 320560.0 -82600.0 -0.84 318440.0 -41600.0 -0.44 -0.9016 -0.9534 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C19 compound treatment 357050.0 -46100.0 -0.47 302450.0 -57600.0 -0.6 -0.7579 -0.9922 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C20 compound treatment 299490.0 -104000.0 -1.05 334170.0 -25900.0 -0.27 -0.9365 -0.861 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C21 compound treatment 410470.0 7320.0 0.07 333280.0 -26800.0 -0.28 -0.1456 -0.5021 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C22 compound treatment 383160.0 -20000.0 -0.2 309200.0 -50800.0 -0.53 -0.5203 -0.9127 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C23 compound treatment 383040.0 -20100.0 -0.2 361320.0 1290.0 0.01 -0.135 -0.6591 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 C24 compound treatment 331730.0 -71400.0 -0.73 305440.0 -54600.0 -0.57 -0.9177 -0.9931 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D01 compound treatment 415540.0 12400.0 0.13 349120.0 -10900.0 -0.11 0.0082 0.048 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D02 compound treatment 459420.0 56300.0 0.57 384160.0 24100.0 0.25 0.5831 0.9326 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D03 compound treatment 377340.0 -25800.0 -0.26 314030.0 -46000.0 -0.48 -0.5263 -0.9591 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D04 compound treatment 455800.0 52700.0 0.54 275050.0 -85000.0 -0.89 -0.2513 -0.2419 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D05 compound treatment 185030.0 -218000.0 -2.22 175960.0 -184000.0 -1.93 -2.9311 -0.9976 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D06 compound treatment 399440.0 -3710.0 -0.04 276840.0 -83200.0 -0.87 -0.643 -0.737 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D07 compound treatment 430170.0 27000.0 0.27 375870.0 15800.0 0.17 0.3115 0.9709 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D08 compound treatment 384170.0 -19000.0 -0.19 346990.0 -13000.0 -0.14 -0.233 -0.9858 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D09 compound treatment 325210.0 -77900.0 -0.79 330790.0 -29200.0 -0.31 -0.7767 -0.9146 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D10 compound treatment 374320.0 -28800.0 -0.29 357560.0 -2480.0 -0.03 -0.2255 -0.7667 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D11 mock treatment 456000.0 52900.0 0.54 371880.0 11800.0 0.12 0.4675 0.8482 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D12 mock treatment 417000.0 13900.0 0.14 392130.0 32100.0 0.34 0.3373 0.9253 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D13 compound treatment 424410.0 21300.0 0.22 389150.0 29100.0 0.31 0.3685 0.9857 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D14 compound treatment 379680.0 -23500.0 -0.24 273460.0 -86600.0 -0.91 -0.8101 -0.8637 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D15 mock treatment 428540.0 25400.0 0.26 337030.0 -23000.0 -0.24 0.012 0.034 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D16 mock treatment 456270.0 53100.0 0.54 360660.0 625.0 0.01 0.3863 0.7156 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D17 compound treatment 357240.0 -45900.0 -0.47 387330.0 27300.0 0.29 -0.1277 -0.2333 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D18 compound treatment 354500.0 -48600.0 -0.49 320480.0 -39600.0 -0.41 -0.6426 -0.9962 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D19 compound treatment 347310.0 -55800.0 -0.57 366610.0 6580.0 0.07 -0.3525 -0.6167 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D20 compound treatment 375590.0 -27600.0 -0.28 295220.0 -64800.0 -0.68 -0.6782 -0.9233 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D21 compound treatment 405940.0 2790.0 0.03 361470.0 1440.0 0.02 0.0307 0.956 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D22 compound treatment 378400.0 -24700.0 -0.25 356240.0 -3800.0 -0.04 -0.206 -0.8089 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D23 compound treatment 333040.0 -70100.0 -0.71 319750.0 -40300.0 -0.42 -0.8022 -0.9688 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 D24 compound treatment 320500.0 -82600.0 -0.84 304990.0 -55000.0 -0.58 -1.0017 -0.9832 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E01 mock treatment 430880.0 27700.0 0.28 395280.0 35200.0 0.37 0.4604 0.9911 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E02 mock treatment 468270.0 65100.0 0.66 415100.0 55100.0 0.58 0.8759 0.9977 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E03 compound treatment 429030.0 25900.0 0.26 356500.0 -3540.0 -0.04 0.1598 0.6016 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E04 compound treatment 343320.0 -59800.0 -0.61 326810.0 -33200.0 -0.35 -0.6761 -0.965 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E05 compound treatment 387840.0 -15300.0 -0.16 373130.0 13100.0 0.14 -0.013 -0.0626 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E06 compound treatment 405760.0 2610.0 0.03 323040.0 -37000.0 -0.39 -0.2553 -0.6572 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E07 compound treatment 353220.0 -49900.0 -0.51 326370.0 -33700.0 -0.35 -0.6082 -0.9842 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E08 compound treatment 473380.0 70200.0 0.71 289760.0 -70300.0 -0.74 -0.016 -0.0156 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E09 mock treatment 454290.0 51100.0 0.52 341770.0 -18300.0 -0.19 0.2322 0.4192 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E10 mock treatment 412000.0 8850.0 0.09 374730.0 14700.0 0.15 0.1725 0.9672 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E11 compound treatment 408400.0 5250.0 0.05 369760.0 9730.0 0.1 0.1098 0.9544 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E12 compound treatment 420860.0 17700.0 0.18 382480.0 22400.0 0.24 0.2935 0.9913 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E13 compound treatment 415200.0 12100.0 0.12 326580.0 -33500.0 -0.35 -0.1613 -0.4343 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E14 compound treatment 406960.0 3810.0 0.04 373970.0 13900.0 0.15 0.1306 0.8647 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E15 compound treatment 410240.0 7090.0 0.07 305600.0 -54400.0 -0.57 -0.3523 -0.6129 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E16 compound treatment 421340.0 18200.0 0.18 355390.0 -4650.0 -0.05 0.0963 0.5038 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E17 mock treatment 431130.0 28000.0 0.28 348960.0 -11100.0 -0.12 0.119 0.3875 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E18 mock treatment 445190.0 42000.0 0.43 388860.0 28800.0 0.3 0.5156 0.9856 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E19 compound treatment 379860.0 -23300.0 -0.24 302580.0 -57500.0 -0.6 -0.593 -0.9168 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E20 compound treatment 386120.0 -17000.0 -0.17 372840.0 12800.0 0.13 -0.0275 -0.1256 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E21 compound treatment 405680.0 2530.0 0.03 336380.0 -23700.0 -0.25 -0.1571 -0.6304 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E22 compound treatment 420480.0 17300.0 0.18 343360.0 -16700.0 -0.17 0.001 0.004 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E23 compound treatment 369560.0 -33600.0 -0.34 378590.0 18600.0 0.19 -0.1039 -0.2645 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 E24 compound treatment 414670.0 11500.0 0.12 412160.0 52100.0 0.55 0.469 0.8396 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F01 mock treatment 433140.0 30000.0 0.3 476220.0 116000.0 1.22 1.0763 0.8577 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F02 mock treatment 408440.0 5290.0 0.05 275490.0 -84500.0 -0.89 -0.5884 -0.663 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F03 compound treatment 372090.0 -31100.0 -0.32 280800.0 -79200.0 -0.83 -0.8102 -0.9122 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F04 compound treatment 357200.0 -45900.0 -0.47 244280.0 -116000.0 -1.21 -1.1878 -0.914 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F05 compound treatment 397560.0 -5590.0 -0.06 332700.0 -27300.0 -0.29 -0.2427 -0.8312 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F06 compound treatment 358290.0 -44900.0 -0.46 320500.0 -39500.0 -0.41 -0.6153 -0.9989 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F07 compound treatment 474080.0 70900.0 0.72 334100.0 -25900.0 -0.27 0.3175 0.4122 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F08 compound treatment 436960.0 33800.0 0.34 314410.0 -45600.0 -0.48 -0.0951 -0.1615 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F09 mock treatment 437020.0 33900.0 0.34 274270.0 -85800.0 -0.9 -0.392 -0.4074 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F10 mock treatment 442850.0 39700.0 0.4 340720.0 -19300.0 -0.2 0.1422 0.315 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F11 compound treatment 355170.0 -48000.0 -0.49 338370.0 -21700.0 -0.23 -0.5053 -0.9395 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F12 compound treatment 418610.0 15500.0 0.16 331780.0 -28300.0 -0.3 -0.0982 -0.2931 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F13 compound treatment 246720.0 -156000.0 -1.59 201690.0 -158000.0 -1.66 -2.2972 -0.9998 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F14 compound treatment 408380.0 5230.0 0.05 319200.0 -40800.0 -0.43 -0.265 -0.6145 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F15 compound treatment 430600.0 27500.0 0.28 321060.0 -39000.0 -0.41 -0.0915 -0.185 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F16 compound treatment 460920.0 57800.0 0.59 325920.0 -34100.0 -0.36 0.1624 0.2362 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F17 mock treatment 459330.0 56200.0 0.57 338970.0 -21100.0 -0.22 0.2476 0.4046 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F18 mock treatment 382560.0 -20600.0 -0.21 354150.0 -5890.0 -0.06 -0.1916 -0.8781 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F19 compound treatment 305660.0 -97500.0 -0.99 318050.0 -42000.0 -0.44 -1.0116 -0.9332 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F20 compound treatment 143840.0 -259000.0 -2.64 123970.0 -236000.0 -2.47 -3.6123 -0.9995 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F21 compound treatment 425050.0 21900.0 0.22 371910.0 11900.0 0.12 0.2453 0.9623 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F22 compound treatment 446910.0 43800.0 0.44 343420.0 -16600.0 -0.17 0.1914 0.4007 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F23 compound treatment 348110.0 -55000.0 -0.56 279530.0 -80500.0 -0.84 -0.9919 -0.9801 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 F24 compound treatment 373930.0 -29200.0 -0.3 317690.0 -42300.0 -0.44 -0.5237 -0.9809 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G01 compound treatment 439760.0 36600.0 0.37 349890.0 -10100.0 -0.11 0.1879 0.4856 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G02 compound treatment 528970.0 126000.0 1.28 344500.0 -15500.0 -0.16 0.789 0.6122 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G03 mock treatment 350150.0 -53000.0 -0.54 370370.0 10300.0 0.11 -0.3043 -0.5539 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G04 mock treatment 397610.0 -5540.0 -0.06 346560.0 -13500.0 -0.14 -0.1396 -0.9187 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G05 compound treatment 214850.0 -188000.0 -1.91 309710.0 -50300.0 -0.53 -1.7259 -0.8695 PK04_181123 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G06 compound treatment 379910.0 -23200.0 -0.24 328030.0 -32000.0 -0.34 -0.4041 -0.9853 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G07 compound treatment 367850.0 -35300.0 -0.36 384570.0 24500.0 0.26 -0.0719 -0.1629 PK04_181125 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G08 compound treatment 428910.0 25800.0 0.26 393320.0 33300.0 0.35 0.4317 0.99 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G09 compound treatment 292770.0 -110000.0 -1.12 342310.0 -17700.0 -0.19 -0.9245 -0.8131 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G10 compound treatment 509850.0 107000.0 1.08 391710.0 31700.0 0.33 1.0014 0.8831 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G11 compound treatment 309770.0 -93400.0 -0.95 265440.0 -94600.0 -0.99 -1.3718 -0.9998 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G12 compound treatment 432750.0 29600.0 0.3 376550.0 16500.0 0.17 0.3351 0.9655 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G13 compound treatment 412000.0 8850.0 0.09 353310.0 -6730.0 -0.07 0.0138 0.1205 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G14 compound treatment 444550.0 41400.0 0.42 355600.0 -4440.0 -0.05 0.2646 0.6252 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G15 compound treatment 396100.0 -7050.0 -0.07 303130.0 -56900.0 -0.6 -0.4723 -0.7864 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G16 compound treatment 483060.0 79900.0 0.81 318510.0 -41500.0 -0.44 0.2666 0.2893 3561954 PK04_181134 COc1ccccc1/C=C/CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G17 compound treatment 353930.0 -49200.0 -0.5 311650.0 -48400.0 -0.51 -0.7121 -1.0 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G18 compound treatment 370400.0 -32700.0 -0.33 340090.0 -19900.0 -0.21 -0.3831 -0.9749 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G19 mock treatment 438010.0 34900.0 0.35 368160.0 8130.0 0.09 0.3107 0.8528 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G20 mock treatment 412730.0 9580.0 0.1 310400.0 -49600.0 -0.52 -0.2989 -0.5649 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G21 compound treatment 405800.0 2650.0 0.03 364670.0 4640.0 0.05 0.0534 0.9613 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G22 compound treatment 319850.0 -83300.0 -0.85 289710.0 -70300.0 -0.74 -1.1196 -0.9976 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G23 compound treatment 367520.0 -35600.0 -0.36 277090.0 -82900.0 -0.87 -0.8705 -0.9247 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 G24 compound treatment 405720.0 2570.0 0.03 380850.0 20800.0 0.22 0.1727 0.7862 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H01 compound treatment 445440.0 42300.0 0.43 376160.0 16100.0 0.17 0.4233 0.9168 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H02 compound treatment 366110.0 -37000.0 -0.38 343050.0 -17000.0 -0.18 -0.392 -0.9415 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H03 mock treatment 317310.0 -85800.0 -0.87 411120.0 51100.0 0.54 -0.2383 -0.2329 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H04 mock treatment 368740.0 -34400.0 -0.35 332970.0 -27100.0 -0.28 -0.4478 -0.9946 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H05 compound treatment 338240.0 -64900.0 -0.66 267420.0 -92600.0 -0.97 -1.1526 -0.9823 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H06 compound treatment 436320.0 33200.0 0.34 360960.0 925.0 0.01 0.2452 0.7271 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H07 compound treatment 474640.0 71500.0 0.73 411200.0 51200.0 0.54 0.8928 0.9888 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H08 compound treatment 432100.0 29000.0 0.29 313710.0 -46300.0 -0.49 -0.1352 -0.2382 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H09 compound treatment 299620.0 -104000.0 -1.05 293470.0 -66600.0 -0.7 -1.2371 -0.9801 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H10 compound treatment 409690.0 6540.0 0.07 270880.0 -89200.0 -0.93 -0.6135 -0.6551 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H11 compound treatment 418900.0 15800.0 0.16 334100.0 -25900.0 -0.27 -0.079 -0.2504 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H12 compound treatment 255260.0 -148000.0 -1.5 360160.0 125.0 0.0 -1.0618 -0.7065 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H13 compound treatment 385440.0 -17700.0 -0.18 230260.0 -130000.0 -1.36 -1.0887 -0.7938 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H14 compound treatment 401070.0 -2080.0 -0.02 340100.0 -19900.0 -0.21 -0.1626 -0.7747 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H15 compound treatment 440500.0 37400.0 0.38 358560.0 -1480.0 -0.02 0.2575 0.6778 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H16 compound treatment 316330.0 -86800.0 -0.88 217440.0 -143000.0 -1.49 -1.6803 -0.9684 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H17 compound treatment 418120.0 15000.0 0.15 377070.0 17000.0 0.18 0.2338 0.9968 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H18 compound treatment 324640.0 -78500.0 -0.8 271930.0 -88100.0 -0.92 -1.2169 -0.9974 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H19 mock treatment 452580.0 49400.0 0.5 342720.0 -17300.0 -0.18 0.2269 0.4249 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H20 mock treatment 376010.0 -27100.0 -0.28 374880.0 14800.0 0.16 -0.085 -0.2686 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H21 compound treatment 343710.0 -59400.0 -0.6 222470.0 -138000.0 -1.44 -1.4463 -0.9255 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H22 compound treatment 11680.0 -391000.0 -3.98 9040.0 -351000.0 -3.68 -5.4134 -0.9992 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H23 compound treatment 15140.0 -388000.0 -3.94 10570.0 -349000.0 -3.66 -5.3772 -0.9993 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 H24 compound treatment 376980.0 -26200.0 -0.27 320480.0 -39600.0 -0.41 -0.4811 -0.977 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I01 compound treatment 367840.0 -35300.0 -0.36 283490.0 -76500.0 -0.8 -0.8208 -0.9342 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I02 compound treatment 325630.0 -77500.0 -0.79 425360.0 65300.0 0.68 -0.0731 -0.07 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I03 compound treatment 359430.0 -43700.0 -0.44 324210.0 -35800.0 -0.38 -0.5796 -0.9965 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I04 compound treatment 328220.0 -74900.0 -0.76 318680.0 -41400.0 -0.43 -0.8448 -0.9643 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I05 mock treatment 449020.0 45900.0 0.47 332000.0 -28000.0 -0.29 0.1219 0.2213 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I06 mock treatment 353790.0 -49400.0 -0.5 359620.0 -415.0 0.0 -0.3578 -0.7132 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I07 compound treatment 310300.0 -92800.0 -0.94 290800.0 -69200.0 -0.73 -1.1801 -0.9916 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I08 compound treatment 439170.0 36000.0 0.37 428290.0 68300.0 0.72 0.7645 0.9516 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I09 compound treatment 445630.0 42500.0 0.43 274180.0 -85900.0 -0.9 -0.3308 -0.3316 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I10 compound treatment 317640.0 -85500.0 -0.87 133840.0 -226000.0 -2.37 -2.2903 -0.9073 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I11 compound treatment 377130.0 -26000.0 -0.26 309730.0 -50300.0 -0.53 -0.5597 -0.9491 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I12 compound treatment 421140.0 18000.0 0.18 376500.0 16500.0 0.17 0.2513 0.9996 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I13 compound treatment 490880.0 87700.0 0.89 319520.0 -40500.0 -0.42 0.3302 0.3344 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I14 compound treatment 449980.0 46800.0 0.48 405670.0 45600.0 0.48 0.6746 1.0 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I15 compound treatment 316010.0 -87100.0 -0.89 266980.0 -93100.0 -0.97 -1.3156 -0.9988 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I16 compound treatment 446330.0 43200.0 0.44 372400.0 12400.0 0.13 0.4019 0.8784 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I17 compound treatment 384870.0 -18300.0 -0.19 255480.0 -105000.0 -1.1 -0.906 -0.8154 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I18 compound treatment 433280.0 30100.0 0.31 373860.0 13800.0 0.14 0.3189 0.9416 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I19 compound treatment 501090.0 97900.0 1.0 365980.0 5950.0 0.06 0.7478 0.7499 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I20 compound treatment 433610.0 30500.0 0.31 340850.0 -19200.0 -0.2 0.0767 0.2079 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I21 mock treatment 413990.0 10800.0 0.11 300120.0 -59900.0 -0.63 -0.366 -0.5743 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I22 mock treatment 352990.0 -50200.0 -0.51 316640.0 -43400.0 -0.45 -0.6819 -0.9984 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I23 compound treatment 349850.0 -53300.0 -0.54 316200.0 -43800.0 -0.46 -0.7078 -0.9966 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 I24 compound treatment 457620.0 54500.0 0.55 380450.0 20400.0 0.21 0.5427 0.9145 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J01 compound treatment 453030.0 49900.0 0.51 336060.0 -24000.0 -0.25 0.1808 0.3196 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J02 compound treatment 180240.0 -223000.0 -2.27 214780.0 -145000.0 -1.52 -2.6779 -0.9813 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J03 compound treatment 254980.0 -148000.0 -1.51 309390.0 -50600.0 -0.53 -1.4399 -0.9019 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J04 compound treatment 302120.0 -101000.0 -1.03 215880.0 -144000.0 -1.51 -1.794 -0.9823 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J05 mock treatment 363320.0 -39800.0 -0.4 332610.0 -27400.0 -0.29 -0.4894 -0.9859 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J06 mock treatment 474350.0 71200.0 0.72 313030.0 -47000.0 -0.49 0.1634 0.1867 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J07 compound treatment 410840.0 7690.0 0.08 283200.0 -76800.0 -0.81 -0.514 -0.6355 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J08 compound treatment 248640.0 -155000.0 -1.57 67250.0 -293000.0 -3.07 -3.2794 -0.9516 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J09 compound treatment 323310.0 -79800.0 -0.81 248480.0 -112000.0 -1.17 -1.4002 -0.9841 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J10 compound treatment 230970.0 -172000.0 -1.75 64480.0 -296000.0 -3.1 -3.4269 -0.9635 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J11 compound treatment 396680.0 -6470.0 -0.07 304070.0 -56000.0 -0.59 -0.4611 -0.7815 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J12 compound treatment 405780.0 2630.0 0.03 331690.0 -28300.0 -0.3 -0.1911 -0.6409 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J13 compound treatment 534560.0 131000.0 1.34 326720.0 -33300.0 -0.35 0.6975 0.5053 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J14 compound treatment 438850.0 35700.0 0.36 323380.0 -36700.0 -0.38 -0.015 -0.0285 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J15 compound treatment 430440.0 27300.0 0.28 383680.0 23600.0 0.25 0.3713 0.9984 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J16 compound treatment 434760.0 31600.0 0.32 351870.0 -8170.0 -0.09 0.1666 0.5013 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J17 compound treatment 331940.0 -71200.0 -0.72 311700.0 -48300.0 -0.51 -0.8698 -0.9848 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J18 compound treatment 411890.0 8740.0 0.09 300640.0 -59400.0 -0.62 -0.3772 -0.6001 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J19 compound treatment 450830.0 47700.0 0.48 376720.0 16700.0 0.17 0.4662 0.9051 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J20 compound treatment 517490.0 114000.0 1.16 367550.0 7520.0 0.08 0.8773 0.7533 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J21 mock treatment 468000.0 64900.0 0.66 320850.0 -39200.0 -0.41 0.1757 0.2263 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J22 mock treatment 407310.0 4160.0 0.04 363360.0 3330.0 0.03 0.0545 0.9954 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J23 compound treatment 315840.0 -87300.0 -0.89 273480.0 -86600.0 -0.91 -1.2686 -0.9999 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 J24 compound treatment 389050.0 -14100.0 -0.14 348580.0 -11500.0 -0.12 -0.1862 -0.9961 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K01 compound treatment 436970.0 33800.0 0.34 435870.0 75800.0 0.79 0.8049 0.9297 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K02 compound treatment 370100.0 -33000.0 -0.34 320690.0 -39300.0 -0.41 -0.529 -0.9948 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K03 compound treatment 350720.0 -52400.0 -0.53 251260.0 -109000.0 -1.14 -1.1826 -0.94 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K04 compound treatment 358150.0 -45000.0 -0.46 313980.0 -46100.0 -0.48 -0.6646 -0.9996 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K05 compound treatment 412250.0 9100.0 0.09 312920.0 -47100.0 -0.49 -0.2837 -0.5648 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K06 compound treatment 309660.0 -93500.0 -0.95 307100.0 -52900.0 -0.55 -1.064 -0.9672 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K07 mock treatment 367960.0 -35200.0 -0.36 378370.0 18300.0 0.19 -0.117 -0.2883 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K08 mock treatment 383040.0 -20100.0 -0.2 315650.0 -44400.0 -0.47 -0.4733 -0.9318 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K09 compound treatment 217600.0 -186000.0 -1.89 212000.0 -148000.0 -1.55 -2.4301 -0.9953 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K10 compound treatment 418400.0 15300.0 0.15 297960.0 -62100.0 -0.65 -0.3503 -0.524 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K11 compound treatment 233170.0 -170000.0 -1.73 241370.0 -119000.0 -1.24 -2.1006 -0.987 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K12 compound treatment 517150.0 114000.0 1.16 397310.0 37300.0 0.39 1.0953 0.8959 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K13 compound treatment 385830.0 -17300.0 -0.18 256320.0 -104000.0 -1.09 -0.8929 -0.8111 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K14 compound treatment 368740.0 -34400.0 -0.35 441150.0 81100.0 0.85 0.3537 0.3849 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K15 mock treatment 426610.0 23500.0 0.24 439840.0 79800.0 0.84 0.7598 0.8739 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K16 mock treatment 411240.0 8090.0 0.08 420020.0 60000.0 0.63 0.5025 0.7928 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K17 compound treatment 362200.0 -40900.0 -0.42 347400.0 -12600.0 -0.13 -0.3879 -0.8882 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K18 compound treatment 457330.0 54200.0 0.55 354760.0 -5280.0 -0.06 0.3502 0.6329 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K19 compound treatment 446350.0 43200.0 0.44 344280.0 -15800.0 -0.17 0.1937 0.413 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K20 compound treatment 519780.0 117000.0 1.19 363400.0 3370.0 0.04 0.863 0.7278 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K21 compound treatment 412400.0 9250.0 0.09 405060.0 45000.0 0.47 0.4 0.8317 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K22 compound treatment 449190.0 46000.0 0.47 383120.0 23100.0 0.24 0.5019 0.9529 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K23 mock treatment 434100.0 31000.0 0.31 461640.0 102000.0 1.06 0.9752 0.8785 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 K24 mock treatment 429810.0 26700.0 0.27 368590.0 8560.0 0.09 0.255 0.8934 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L01 compound treatment 421440.0 18300.0 0.19 337090.0 -22900.0 -0.24 -0.0386 -0.1269 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L02 compound treatment 418720.0 15600.0 0.16 297440.0 -62600.0 -0.66 -0.3519 -0.5215 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L03 compound treatment 297470.0 -106000.0 -1.07 255200.0 -105000.0 -1.1 -1.5361 -0.9999 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L04 compound treatment 53090.0 -350000.0 -3.56 39010.0 -321000.0 -3.36 -4.8938 -0.9996 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L05 compound treatment 276880.0 -126000.0 -1.28 214080.0 -146000.0 -1.53 -1.9887 -0.9962 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L06 compound treatment 433340.0 30200.0 0.31 300800.0 -59200.0 -0.62 -0.2219 -0.3205 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L07 mock treatment 370510.0 -32600.0 -0.33 336350.0 -23700.0 -0.25 -0.41 -0.9898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L08 mock treatment 446400.0 43300.0 0.44 410180.0 50100.0 0.53 0.6823 0.9961 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L09 compound treatment 464520.0 61400.0 0.62 351070.0 -8970.0 -0.09 0.3746 0.5939 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L10 compound treatment 167040.0 -236000.0 -2.4 134650.0 -225000.0 -2.36 -3.3664 -1.0 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L11 compound treatment 474910.0 71800.0 0.73 325560.0 -34500.0 -0.36 0.2602 0.3198 1006359 PK04_181227 Cc1cccc[n+]1C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L12 compound treatment 325670.0 -77500.0 -0.79 272050.0 -88000.0 -0.92 -1.2086 -0.9969 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L13 compound treatment 402830.0 -320.0 0.0 376280.0 16200.0 0.17 0.1181 0.6935 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L14 compound treatment 433050.0 29900.0 0.3 360360.0 325.0 0.0 0.2173 0.715 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L15 mock treatment 496850.0 93700.0 0.95 332270.0 -27800.0 -0.29 0.4676 0.4696 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L16 mock treatment 309280.0 -93900.0 -0.95 330880.0 -29200.0 -0.31 -0.8905 -0.8891 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L17 compound treatment 439950.0 36800.0 0.37 332490.0 -27500.0 -0.29 0.0604 0.1278 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L18 compound treatment 463210.0 60100.0 0.61 357920.0 -2120.0 -0.02 0.4159 0.681 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L19 compound treatment 414650.0 11500.0 0.12 384710.0 24700.0 0.26 0.2654 0.9356 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L20 compound treatment 206790.0 -196000.0 -2.0 166330.0 -194000.0 -2.03 -2.8461 -1.0 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L21 compound treatment 438950.0 35800.0 0.36 309650.0 -50400.0 -0.53 -0.116 -0.181 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L22 compound treatment 155620.0 -248000.0 -2.52 83680.0 -276000.0 -2.9 -3.8261 -0.9975 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L23 mock treatment 456400.0 53300.0 0.54 370660.0 10600.0 0.11 0.4614 0.8351 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 L24 mock treatment 456450.0 53300.0 0.54 353370.0 -6670.0 -0.07 0.3336 0.6109 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M01 compound treatment 389180.0 -14000.0 -0.14 306360.0 -53700.0 -0.56 -0.498 -0.8587 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M02 compound treatment 202160.0 -201000.0 -2.04 182880.0 -177000.0 -1.86 -2.7567 -0.9989 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M03 compound treatment 237320.0 -166000.0 -1.69 199420.0 -161000.0 -1.68 -2.3816 -1.0 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M04 compound treatment 22990.0 -380000.0 -3.86 20540.0 -339000.0 -3.56 -5.2469 -0.9991 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M05 compound treatment 153990.0 -249000.0 -2.53 189810.0 -170000.0 -1.78 -3.0515 -0.9853 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M06 compound treatment 404510.0 1360.0 0.01 376900.0 16900.0 0.18 0.1347 0.7601 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M07 compound treatment 302930.0 -100000.0 -1.02 274100.0 -85900.0 -0.9 -1.3568 -0.9981 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M08 compound treatment 164910.0 -238000.0 -2.42 238980.0 -121000.0 -1.27 -2.6088 -0.9545 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M09 mock treatment 399040.0 -4110.0 -0.04 411140.0 51100.0 0.54 0.3491 0.65 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M10 mock treatment 333640.0 -69500.0 -0.71 388560.0 28500.0 0.3 -0.2881 -0.3757 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M11 compound treatment 360190.0 -43000.0 -0.44 250940.0 -109000.0 -1.14 -1.117 -0.9129 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M12 compound treatment 477210.0 74100.0 0.75 424170.0 64100.0 0.67 1.0073 0.9984 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M13 mock treatment 398460.0 -4690.0 -0.05 345620.0 -14400.0 -0.15 -0.1405 -0.8871 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M14 mock treatment 356010.0 -47100.0 -0.48 404960.0 44900.0 0.47 -0.0059 -0.0088 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M15 compound treatment 372230.0 -30900.0 -0.31 278270.0 -81800.0 -0.86 -0.828 -0.9073 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M16 compound treatment 161830.0 -241000.0 -2.45 57760.0 -302000.0 -3.17 -3.9735 -0.992 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M17 compound treatment 297460.0 -106000.0 -1.07 277120.0 -82900.0 -0.87 -1.3737 -0.9945 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M18 compound treatment 359000.0 -44100.0 -0.45 362050.0 2020.0 0.02 -0.3023 -0.6731 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M19 compound treatment 456800.0 53700.0 0.55 319070.0 -41000.0 -0.43 0.082 0.1182 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M20 compound treatment 231940.0 -171000.0 -1.74 221090.0 -139000.0 -1.46 -2.2597 -0.9961 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M21 compound treatment 391460.0 -11700.0 -0.12 296830.0 -63200.0 -0.66 -0.5523 -0.8208 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M22 compound treatment 461920.0 58800.0 0.6 341520.0 -18500.0 -0.19 0.2851 0.4541 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M23 compound treatment 322010.0 -81100.0 -0.82 223770.0 -136000.0 -1.43 -1.5926 -0.966 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 M24 compound treatment 378560.0 -24600.0 -0.25 291490.0 -68500.0 -0.72 -0.6845 -0.9002 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N01 compound treatment 432930.0 29800.0 0.3 340860.0 -19200.0 -0.2 0.0719 0.198 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N02 compound treatment 415560.0 12400.0 0.13 353350.0 -6690.0 -0.07 0.0396 0.2748 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N03 compound treatment 330240.0 -72900.0 -0.74 267840.0 -92200.0 -0.97 -1.207 -0.9914 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N04 compound treatment 342800.0 -60300.0 -0.61 285560.0 -74500.0 -0.78 -0.9854 -0.9929 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N05 compound treatment 365710.0 -37400.0 -0.38 380120.0 20100.0 0.21 -0.1202 -0.2765 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N06 compound treatment 310340.0 -92800.0 -0.94 341630.0 -18400.0 -0.19 -0.8033 -0.8344 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N07 compound treatment 273240.0 -130000.0 -1.32 285400.0 -74600.0 -0.78 -1.4864 -0.9688 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N08 compound treatment 440240.0 37100.0 0.38 289140.0 -70900.0 -0.74 -0.2587 -0.3106 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N09 mock treatment 352720.0 -50400.0 -0.51 475170.0 115000.0 1.21 0.4906 0.3743 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N10 mock treatment 331910.0 -71200.0 -0.72 366800.0 6770.0 0.07 -0.4618 -0.6348 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N11 compound treatment 470800.0 67700.0 0.69 356080.0 -3960.0 -0.04 0.4568 0.6633 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N12 compound treatment 427200.0 24100.0 0.24 343090.0 -16900.0 -0.18 0.0473 0.1565 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N13 mock treatment 446360.0 43200.0 0.44 344540.0 -15500.0 -0.16 0.1957 0.418 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N14 mock treatment 318470.0 -84700.0 -0.86 335170.0 -24900.0 -0.26 -0.7927 -0.8817 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N15 compound treatment 334670.0 -68500.0 -0.7 383900.0 23900.0 0.25 -0.3153 -0.4263 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N16 compound treatment 455400.0 52300.0 0.53 469960.0 110000.0 1.15 1.1899 0.9382 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N17 compound treatment 366920.0 -36200.0 -0.37 363950.0 3920.0 0.04 -0.2313 -0.6245 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N18 compound treatment 415750.0 12600.0 0.13 368920.0 8890.0 0.09 0.1564 0.9877 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N19 compound treatment 378920.0 -24200.0 -0.25 287680.0 -72400.0 -0.76 -0.7102 -0.891 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N20 compound treatment 212250.0 -191000.0 -1.94 202560.0 -157000.0 -1.65 -2.5384 -0.9968 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N21 compound treatment 312070.0 -91100.0 -0.93 258480.0 -102000.0 -1.06 -1.4069 -0.9976 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N22 compound treatment 452820.0 49700.0 0.5 399520.0 39500.0 0.41 0.6494 0.9951 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N23 compound treatment 451240.0 48100.0 0.49 343780.0 -16300.0 -0.17 0.2251 0.435 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 N24 compound treatment 442580.0 39400.0 0.4 419700.0 59700.0 0.63 0.7254 0.9769 1004341 PK04_181276 c1ccc2cnccc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O01 compound treatment 399700.0 -3450.0 -0.04 394180.0 34100.0 0.36 0.2282 0.6348 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O02 compound treatment 182260.0 -221000.0 -2.24 188350.0 -172000.0 -1.8 -2.8592 -0.994 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O03 compound treatment 321280.0 -81900.0 -0.83 234940.0 -125000.0 -1.31 -1.5151 -0.9759 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O04 compound treatment 143840.0 -259000.0 -2.64 96230.0 -264000.0 -2.76 -3.8178 -0.9997 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O05 compound treatment 311680.0 -91500.0 -0.93 329980.0 -30100.0 -0.31 -0.8799 -0.8966 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O06 compound treatment 147700.0 -255000.0 -2.6 118990.0 -241000.0 -2.53 -3.6214 -0.9999 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O07 compound treatment 75800.0 -327000.0 -3.33 65150.0 -295000.0 -3.09 -4.537 -0.9993 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O08 compound treatment 116740.0 -286000.0 -2.91 106080.0 -254000.0 -2.66 -3.9395 -0.999 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O09 compound treatment 14180.0 -389000.0 -3.95 12960.0 -347000.0 -3.64 -5.3664 -0.9991 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O10 compound treatment 357760.0 -45400.0 -0.46 392120.0 32100.0 0.34 -0.0884 -0.155 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O11 mock treatment 384250.0 -18900.0 -0.19 352800.0 -7240.0 -0.08 -0.1894 -0.9173 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O12 mock treatment 390610.0 -12500.0 -0.13 389870.0 29800.0 0.31 0.1309 0.3879 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O13 compound treatment 388920.0 -14200.0 -0.14 285390.0 -74600.0 -0.78 -0.6553 -0.8239 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O14 compound treatment 478400.0 75300.0 0.76 371140.0 11100.0 0.12 0.623 0.8054 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O15 compound treatment 321200.0 -81900.0 -0.83 438360.0 78300.0 0.82 -0.0086 -0.0073 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O16 compound treatment 490590.0 87400.0 0.89 456070.0 96000.0 1.01 1.3398 0.9981 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O17 compound treatment 427910.0 24800.0 0.25 372920.0 12900.0 0.14 0.2734 0.9574 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O18 compound treatment 462730.0 59600.0 0.61 411060.0 51000.0 0.53 0.8062 0.9981 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O19 compound treatment 336200.0 -66900.0 -0.68 354010.0 -6030.0 -0.06 -0.5257 -0.7694 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O20 compound treatment 386190.0 -17000.0 -0.17 462650.0 103000.0 1.08 0.6384 0.5863 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O21 compound treatment 415610.0 12500.0 0.13 421770.0 61700.0 0.65 0.5469 0.8298 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O22 compound treatment 432900.0 29800.0 0.3 467610.0 108000.0 1.13 1.0108 0.8662 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O23 compound treatment 429120.0 26000.0 0.26 386080.0 26000.0 0.27 0.3796 0.9999 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 O24 compound treatment 453470.0 50300.0 0.51 456700.0 96700.0 1.01 1.0777 0.9499 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P01 compound treatment 262080.0 -141000.0 -1.43 214170.0 -146000.0 -1.53 -2.0944 -0.9995 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P02 compound treatment 376600.0 -26500.0 -0.27 376000.0 16000.0 0.17 -0.0725 -0.2284 1015751 PK04_181300 Cc1ccncc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P03 compound treatment 427420.0 24300.0 0.25 350890.0 -9150.0 -0.1 0.1066 0.4031 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P04 compound treatment 431910.0 28800.0 0.29 398900.0 38900.0 0.41 0.4946 0.9868 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P05 compound treatment 265920.0 -137000.0 -1.39 250820.0 -109000.0 -1.14 -1.7952 -0.9952 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P06 compound treatment 415560.0 12400.0 0.13 357760.0 -2280.0 -0.02 0.0723 0.5635 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P07 compound treatment 143130.0 -260000.0 -2.64 106130.0 -254000.0 -2.66 -3.7495 -1.0 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P08 compound treatment 409930.0 6780.0 0.07 283150.0 -76900.0 -0.81 -0.5209 -0.6443 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P09 compound treatment 375680.0 -27500.0 -0.28 321150.0 -38900.0 -0.41 -0.4855 -0.983 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P10 compound treatment 334620.0 -68500.0 -0.7 330290.0 -29700.0 -0.31 -0.7128 -0.9343 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P11 mock treatment 348160.0 -55000.0 -0.56 406240.0 46200.0 0.48 -0.0528 -0.0714 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P12 mock treatment 427850.0 24700.0 0.25 336860.0 -23200.0 -0.24 0.0058 0.0166 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P13 compound treatment 371200.0 -31900.0 -0.32 315220.0 -44800.0 -0.47 -0.5616 -0.9838 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P14 compound treatment 451200.0 48100.0 0.49 383910.0 23900.0 0.25 0.5222 0.9517 1009497 PK04_181310 Cc1cc[n+](C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P15 compound treatment 259710.0 -143000.0 -1.46 250360.0 -110000.0 -1.15 -1.8433 -0.9931 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P16 compound treatment 367300.0 -35800.0 -0.36 432720.0 72700.0 0.76 0.2809 0.3327 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P17 compound treatment 287700.0 -115000.0 -1.17 294800.0 -65200.0 -0.68 -1.3129 -0.9669 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P18 compound treatment 459420.0 56300.0 0.57 352820.0 -7220.0 -0.08 0.3509 0.6083 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P19 compound treatment 340520.0 -62600.0 -0.64 382970.0 22900.0 0.24 -0.2801 -0.4118 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P20 compound treatment 299070.0 -104000.0 -1.06 318590.0 -41400.0 -0.43 -1.0549 -0.9227 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P21 compound treatment 340390.0 -62800.0 -0.64 319200.0 -40800.0 -0.43 -0.7535 -0.9811 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P22 compound treatment 362720.0 -40400.0 -0.41 340590.0 -19400.0 -0.2 -0.4346 -0.9476 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P23 compound treatment 391360.0 -11800.0 -0.12 312390.0 -47600.0 -0.5 -0.4377 -0.8526 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2181 P24 compound treatment 354530.0 -48600.0 -0.49 355300.0 -4740.0 -0.05 -0.3844 -0.7742 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A01 compound treatment 258040.0 -188000.0 -1.91 209330.0 -219000.0 -2.29 -2.9738 -0.9959 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A02 compound treatment 323590.0 -123000.0 -1.25 395770.0 -32400.0 -0.34 -1.1215 -0.868 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A03 compound treatment 317510.0 -129000.0 -1.31 413130.0 -15000.0 -0.16 -1.0365 -0.7865 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A04 compound treatment 310240.0 -136000.0 -1.38 377780.0 -50400.0 -0.53 -1.3507 -0.9128 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A05 compound treatment 291110.0 -155000.0 -1.58 381190.0 -47000.0 -0.49 -1.4629 -0.8857 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A06 compound treatment 294960.0 -151000.0 -1.54 318050.0 -110000.0 -1.15 -1.903 -0.99 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A07 compound treatment 400410.0 -45900.0 -0.47 493360.0 65200.0 0.68 0.1536 0.1857 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A08 compound treatment 396090.0 -50200.0 -0.51 443160.0 15000.0 0.16 -0.2494 -0.4674 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A09 compound treatment 409840.0 -36400.0 -0.37 441410.0 13300.0 0.14 -0.1636 -0.4137 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A10 compound treatment 477870.0 31600.0 0.32 408290.0 -19900.0 -0.21 0.0799 0.2088 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A11 compound treatment 418880.0 -27400.0 -0.28 407970.0 -20200.0 -0.21 -0.3464 -0.9908 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A12 compound treatment 426780.0 -19500.0 -0.2 394050.0 -34100.0 -0.36 -0.3927 -0.9612 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A13 mock treatment 395630.0 -50600.0 -0.51 403800.0 -24400.0 -0.26 -0.5443 -0.9477 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A14 mock treatment 479070.0 32800.0 0.33 455370.0 27200.0 0.29 0.4373 0.997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A15 compound treatment 396930.0 -49300.0 -0.5 415270.0 -12900.0 -0.14 -0.45 -0.8667 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A16 compound treatment 445720.0 -547.0 -0.01 430660.0 2500.0 0.03 0.0146 0.5452 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A17 compound treatment 435970.0 -10300.0 -0.1 452400.0 24200.0 0.25 0.1056 0.3845 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A18 compound treatment 379310.0 -67000.0 -0.68 465560.0 37400.0 0.39 -0.204 -0.2598 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A19 compound treatment 397710.0 -48600.0 -0.49 432870.0 4710.0 0.05 -0.314 -0.6332 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A20 compound treatment 416440.0 -29800.0 -0.3 390970.0 -37200.0 -0.39 -0.4898 -0.9923 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A21 compound treatment 499680.0 53400.0 0.54 516490.0 88300.0 0.93 1.0382 0.9677 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A22 compound treatment 421490.0 -24800.0 -0.25 428830.0 673.0 0.01 -0.1731 -0.687 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A23 compound treatment 419520.0 -26700.0 -0.27 325290.0 -103000.0 -1.08 -0.9543 -0.8585 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 A24 compound treatment 428200.0 -18100.0 -0.18 423080.0 -5080.0 -0.05 -0.1674 -0.876 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B01 compound treatment 463750.0 17500.0 0.18 492650.0 64500.0 0.68 0.6034 0.8637 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B02 compound treatment 409970.0 -36300.0 -0.37 359220.0 -68900.0 -0.72 -0.7716 -0.9513 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B03 compound treatment 425630.0 -20600.0 -0.21 417210.0 -10900.0 -0.11 -0.2294 -0.9597 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B04 compound treatment 344030.0 -102000.0 -1.04 451310.0 23200.0 0.24 -0.5631 -0.5278 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B05 compound treatment 388070.0 -58200.0 -0.59 403580.0 -24600.0 -0.26 -0.6003 -0.9306 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B06 compound treatment 337320.0 -109000.0 -1.11 260000.0 -168000.0 -1.76 -2.0287 -0.9749 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B07 compound treatment 492830.0 46600.0 0.47 431260.0 3100.0 0.03 0.3576 0.7539 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B08 compound treatment 476960.0 30700.0 0.31 484050.0 55900.0 0.59 0.6346 0.9565 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B09 compound treatment 378980.0 -67300.0 -0.68 430490.0 2330.0 0.02 -0.4662 -0.6814 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B10 compound treatment 422080.0 -24200.0 -0.25 410240.0 -17900.0 -0.19 -0.3065 -0.9912 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B11 compound treatment 472530.0 26300.0 0.27 420960.0 -7200.0 -0.08 0.1354 0.4882 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B12 compound treatment 445460.0 -807.0 -0.01 349480.0 -78700.0 -0.82 -0.5887 -0.7141 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B13 mock treatment 467470.0 21200.0 0.22 341550.0 -86600.0 -0.91 -0.4893 -0.5246 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B14 mock treatment 455680.0 9410.0 0.1 516060.0 87900.0 0.92 0.7189 0.7764 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B15 compound treatment 436710.0 -9560.0 -0.1 450350.0 22200.0 0.23 0.0957 0.38 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B16 compound treatment 432010.0 -14300.0 -0.14 383110.0 -45000.0 -0.47 -0.4362 -0.8835 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B17 compound treatment 403880.0 -42400.0 -0.43 338450.0 -89700.0 -0.94 -0.9692 -0.9374 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B18 compound treatment 400370.0 -45900.0 -0.47 412080.0 -16100.0 -0.17 -0.4489 -0.9053 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B19 compound treatment 462030.0 15800.0 0.16 374000.0 -54200.0 -0.57 -0.288 -0.4884 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B20 compound treatment 391220.0 -55000.0 -0.56 432240.0 4080.0 0.04 -0.3653 -0.6511 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B21 compound treatment 428700.0 -17600.0 -0.18 420880.0 -7280.0 -0.08 -0.1801 -0.928 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B22 compound treatment 460250.0 14000.0 0.14 436810.0 8650.0 0.09 0.1646 0.9764 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B23 compound treatment 425240.0 -21000.0 -0.21 479610.0 51500.0 0.54 0.2301 0.3968 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 B24 compound treatment 434570.0 -11700.0 -0.12 411580.0 -16600.0 -0.17 -0.2069 -0.9829 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C01 compound treatment 411090.0 -35200.0 -0.36 401960.0 -26200.0 -0.27 -0.4469 -0.9915 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C02 compound treatment 335560.0 -111000.0 -1.13 426200.0 -1960.0 -0.02 -0.81 -0.7199 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C03 compound treatment 328690.0 -118000.0 -1.19 299920.0 -128000.0 -1.34 -1.7949 -0.9983 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C04 compound treatment 253020.0 -193000.0 -1.96 252400.0 -176000.0 -1.84 -2.6907 -0.9995 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C05 compound treatment 276010.0 -170000.0 -1.73 301120.0 -127000.0 -1.33 -2.1646 -0.9916 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C06 compound treatment 369130.0 -77100.0 -0.78 346720.0 -81400.0 -0.85 -1.1576 -0.9991 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C07 compound treatment 392270.0 -54000.0 -0.55 302560.0 -126000.0 -1.32 -1.3185 -0.9248 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C08 compound treatment 339050.0 -107000.0 -1.09 316590.0 -112000.0 -1.17 -1.597 -0.9994 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C09 compound treatment 438400.0 -7870.0 -0.08 414330.0 -13800.0 -0.14 -0.159 -0.9607 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C10 compound treatment 402780.0 -43500.0 -0.44 402260.0 -25900.0 -0.27 -0.5043 -0.9726 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C11 mock treatment 375680.0 -70600.0 -0.72 317520.0 -111000.0 -1.16 -1.3269 -0.9734 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C12 mock treatment 460070.0 13800.0 0.14 373920.0 -54200.0 -0.57 -0.3026 -0.517 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C13 compound treatment 341680.0 -105000.0 -1.06 305360.0 -123000.0 -1.29 -1.6613 -0.9955 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C14 compound treatment 375360.0 -70900.0 -0.72 393820.0 -34300.0 -0.36 -0.7639 -0.9485 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C15 mock treatment 485760.0 39500.0 0.4 339530.0 -88600.0 -0.93 -0.3728 -0.3685 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C16 mock treatment 422880.0 -23400.0 -0.24 410970.0 -17200.0 -0.18 -0.2954 -0.9906 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C17 compound treatment 398990.0 -47300.0 -0.48 361080.0 -67100.0 -0.7 -0.8367 -0.9828 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C18 compound treatment 353210.0 -93100.0 -0.95 377340.0 -50800.0 -0.53 -1.0452 -0.9631 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C19 compound treatment 222240.0 -224000.0 -2.28 183860.0 -244000.0 -2.56 -3.4197 -0.9983 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C20 compound treatment 419400.0 -26900.0 -0.27 424640.0 -3520.0 -0.04 -0.2191 -0.7953 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C21 compound treatment 398670.0 -47600.0 -0.48 395740.0 -32400.0 -0.34 -0.5822 -0.985 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C22 compound treatment 357560.0 -88700.0 -0.9 443530.0 15400.0 0.16 -0.5235 -0.5717 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C23 compound treatment 418260.0 -28000.0 -0.28 366910.0 -61200.0 -0.64 -0.655 -0.9331 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 C24 compound treatment 352510.0 -93800.0 -0.95 336220.0 -91900.0 -0.96 -1.3548 -1.0 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D01 compound treatment 311750.0 -135000.0 -1.37 430940.0 2780.0 0.03 -0.946 -0.6919 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D02 compound treatment 273410.0 -173000.0 -1.76 291260.0 -137000.0 -1.43 -2.2563 -0.9949 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D03 compound treatment 340830.0 -105000.0 -1.07 415010.0 -13100.0 -0.14 -0.855 -0.7915 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D04 compound treatment 383200.0 -63100.0 -0.64 348080.0 -80100.0 -0.84 -1.0464 -0.9912 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D05 compound treatment 490080.0 43800.0 0.45 426970.0 -1190.0 -0.01 0.306 0.6871 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D06 compound treatment 417760.0 -28500.0 -0.29 322890.0 -105000.0 -1.1 -0.9847 -0.8635 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D07 compound treatment 333490.0 -113000.0 -1.15 405390.0 -22800.0 -0.24 -0.9791 -0.8364 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D08 compound treatment 393610.0 -52700.0 -0.54 360290.0 -67900.0 -0.71 -0.8812 -0.9902 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D09 compound treatment 409380.0 -36900.0 -0.37 427430.0 -727.0 -0.01 -0.2704 -0.7213 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D10 compound treatment 488960.0 42700.0 0.43 365220.0 -62900.0 -0.66 -0.1595 -0.2021 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D11 mock treatment 455480.0 9210.0 0.09 312840.0 -115000.0 -1.21 -0.7881 -0.6504 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D12 mock treatment 411400.0 -34900.0 -0.35 383550.0 -44600.0 -0.47 -0.581 -0.9907 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D13 compound treatment 463880.0 17600.0 0.18 474800.0 46600.0 0.49 0.4721 0.9072 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D14 compound treatment 441630.0 -4640.0 -0.05 440480.0 12300.0 0.13 0.058 0.4218 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D15 mock treatment 431480.0 -14800.0 -0.15 413340.0 -14800.0 -0.16 -0.216 -0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D16 mock treatment 468070.0 21800.0 0.22 405930.0 -22200.0 -0.23 -0.008 -0.0249 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D17 compound treatment 475360.0 29100.0 0.3 365190.0 -63000.0 -0.66 -0.2575 -0.3561 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D18 compound treatment 385980.0 -60300.0 -0.61 337240.0 -90900.0 -0.95 -1.1068 -0.9772 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D19 compound treatment 436970.0 -9300.0 -0.09 348650.0 -79500.0 -0.83 -0.6558 -0.7823 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D20 compound treatment 326720.0 -120000.0 -1.21 429310.0 1150.0 0.01 -0.8505 -0.7 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D21 compound treatment 456960.0 10700.0 0.11 381510.0 -46600.0 -0.49 -0.2688 -0.5368 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D22 compound treatment 360270.0 -86000.0 -0.87 372160.0 -56000.0 -0.59 -1.0328 -0.9812 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D23 compound treatment 408800.0 -37500.0 -0.38 396910.0 -31200.0 -0.33 -0.5007 -0.9972 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 D24 compound treatment 461700.0 15400.0 0.16 449030.0 20900.0 0.22 0.2655 0.9867 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E01 mock treatment 506240.0 60000.0 0.61 497530.0 69400.0 0.73 0.9449 0.9962 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E02 mock treatment 436080.0 -10200.0 -0.1 426240.0 -1920.0 -0.02 -0.0874 -0.8289 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E03 mock treatment 470300.0 24000.0 0.24 412430.0 -15700.0 -0.16 0.0562 0.1907 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E04 compound treatment 402080.0 -44200.0 -0.45 374140.0 -54000.0 -0.57 -0.7177 -0.9934 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E05 compound treatment 413210.0 -33100.0 -0.34 414950.0 -13200.0 -0.14 -0.3354 -0.9231 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E06 compound treatment 395040.0 -51200.0 -0.52 340130.0 -88000.0 -0.92 -1.0203 -0.9634 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E07 compound treatment 468240.0 22000.0 0.22 396650.0 -31500.0 -0.33 -0.0755 -0.1895 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E08 compound treatment 419860.0 -26400.0 -0.27 331640.0 -96500.0 -1.01 -0.9048 -0.8648 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E09 mock treatment 465190.0 18900.0 0.19 490370.0 62200.0 0.65 0.5969 0.8783 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E10 mock treatment 440040.0 -6230.0 -0.06 431270.0 3110.0 0.03 -0.0217 -0.3046 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E11 compound treatment 456640.0 10400.0 0.11 466930.0 38800.0 0.41 0.3618 0.862 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E12 compound treatment 330930.0 -115000.0 -1.17 255310.0 -173000.0 -1.81 -2.1094 -0.9778 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E13 compound treatment 411130.0 -35100.0 -0.36 363650.0 -64500.0 -0.68 -0.7304 -0.9555 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E14 compound treatment 493040.0 46800.0 0.48 409410.0 -18700.0 -0.2 0.1972 0.3834 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E15 compound treatment 302090.0 -144000.0 -1.47 289830.0 -138000.0 -1.45 -2.0608 -1.0 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E16 compound treatment 362660.0 -83600.0 -0.85 426510.0 -1650.0 -0.02 -0.613 -0.7213 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E17 mock treatment 436000.0 -10300.0 -0.1 492720.0 64600.0 0.68 0.4046 0.5911 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E18 mock treatment 425950.0 -20300.0 -0.21 436120.0 7960.0 0.08 -0.087 -0.3907 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E19 compound treatment 369650.0 -76600.0 -0.78 344110.0 -84000.0 -0.88 -1.1732 -0.9981 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E20 compound treatment 464720.0 18500.0 0.19 408920.0 -19200.0 -0.2 -0.0099 -0.036 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E21 compound treatment 451680.0 5410.0 0.06 458810.0 30700.0 0.32 0.266 0.8163 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E22 compound treatment 466670.0 20400.0 0.21 422080.0 -6080.0 -0.06 0.1016 0.4684 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E23 compound treatment 405760.0 -40500.0 -0.41 355930.0 -72200.0 -0.76 -0.8262 -0.959 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 E24 compound treatment 448230.0 1960.0 0.02 376160.0 -52000.0 -0.54 -0.3711 -0.6808 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F01 mock treatment 507790.0 61500.0 0.63 443090.0 14900.0 0.16 0.5527 0.8576 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F02 mock treatment 457440.0 11200.0 0.11 406360.0 -21800.0 -0.23 -0.0812 -0.3184 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F03 compound treatment 488080.0 41800.0 0.42 405480.0 -22700.0 -0.24 0.1324 0.2721 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F04 compound treatment 341440.0 -105000.0 -1.07 312680.0 -115000.0 -1.21 -1.6088 -0.998 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F05 compound treatment 364800.0 -81500.0 -0.83 364180.0 -64000.0 -0.67 -1.0594 -0.9945 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F06 compound treatment 444210.0 -2060.0 -0.02 349280.0 -78900.0 -0.83 -0.5992 -0.7248 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F07 compound treatment 552440.0 106000.0 1.08 346560.0 -81600.0 -0.85 0.1584 0.1151 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F08 compound treatment 507870.0 61600.0 0.63 391370.0 -36800.0 -0.39 0.1701 0.2314 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F09 mock treatment 469310.0 23000.0 0.23 533160.0 105000.0 1.1 0.9435 0.8388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F10 mock treatment 457920.0 11700.0 0.12 390790.0 -37400.0 -0.39 -0.1931 -0.4721 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F11 compound treatment 351690.0 -94600.0 -0.96 454570.0 26400.0 0.28 -0.4839 -0.4838 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F12 compound treatment 380860.0 -65400.0 -0.66 398720.0 -29400.0 -0.31 -0.6881 -0.9391 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F13 compound treatment 396640.0 -49600.0 -0.5 373610.0 -54500.0 -0.57 -0.7607 -0.9981 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F14 compound treatment 389670.0 -56600.0 -0.58 407770.0 -20400.0 -0.21 -0.5577 -0.9091 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F15 compound treatment 407430.0 -38800.0 -0.39 430630.0 2470.0 0.03 -0.2607 -0.6593 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F16 compound treatment 484610.0 38300.0 0.39 370950.0 -57200.0 -0.6 -0.1483 -0.2075 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F17 mock treatment 464120.0 17900.0 0.18 488010.0 59900.0 0.63 0.5717 0.8758 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F18 mock treatment 486000.0 39700.0 0.4 460480.0 32300.0 0.34 0.525 0.9962 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F19 compound treatment 455370.0 9100.0 0.09 436560.0 8400.0 0.09 0.1277 0.9997 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F20 compound treatment 332570.0 -114000.0 -1.16 331150.0 -97000.0 -1.02 -1.5357 -0.998 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F21 compound treatment 454780.0 8510.0 0.09 418830.0 -9330.0 -0.1 -0.0079 -0.0607 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F22 compound treatment 298480.0 -148000.0 -1.5 295090.0 -133000.0 -1.39 -2.0478 -0.9993 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F23 compound treatment 444710.0 -1560.0 -0.02 430630.0 2470.0 0.03 0.0071 0.2351 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 F24 compound treatment 361090.0 -85200.0 -0.87 484640.0 56500.0 0.59 -0.1936 -0.1846 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G01 compound treatment 390340.0 -55900.0 -0.57 517210.0 89100.0 0.93 0.2579 0.2361 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G02 compound treatment 504490.0 58200.0 0.59 519590.0 91400.0 0.96 1.0958 0.9732 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G03 mock treatment 496910.0 50600.0 0.51 397770.0 -30400.0 -0.32 0.1388 0.2293 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G04 mock treatment 446830.0 563.0 0.01 421840.0 -6320.0 -0.07 -0.0428 -0.6435 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G05 compound treatment 354810.0 -91500.0 -0.93 324640.0 -104000.0 -1.08 -1.4241 -0.997 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G06 compound treatment 494720.0 48500.0 0.49 429600.0 1440.0 0.02 0.3589 0.7285 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G07 compound treatment 408320.0 -37900.0 -0.39 393410.0 -34700.0 -0.36 -0.5301 -0.9996 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G08 compound treatment 450440.0 4170.0 0.04 458170.0 30000.0 0.31 0.2523 0.7953 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G09 compound treatment 441360.0 -4910.0 -0.05 400710.0 -27400.0 -0.29 -0.2386 -0.8175 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G10 compound treatment 417120.0 -29100.0 -0.3 404480.0 -23700.0 -0.25 -0.3849 -0.9961 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G11 compound treatment 460160.0 13900.0 0.14 429870.0 1710.0 0.02 0.1125 0.7906 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G12 compound treatment 477990.0 31700.0 0.32 346720.0 -81400.0 -0.85 -0.3754 -0.4116 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G13 compound treatment 406150.0 -40100.0 -0.41 354360.0 -73800.0 -0.77 -0.835 -0.9553 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G14 compound treatment 497230.0 51000.0 0.52 376960.0 -51200.0 -0.54 -0.0131 -0.0176 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G15 compound treatment 419330.0 -26900.0 -0.27 340740.0 -87400.0 -0.92 -0.8412 -0.88 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G16 compound treatment 449050.0 2780.0 0.03 450950.0 22800.0 0.24 0.1889 0.7854 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G17 compound treatment 496080.0 49800.0 0.51 471320.0 43200.0 0.45 0.6777 0.9984 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G18 compound treatment 360830.0 -85400.0 -0.87 421130.0 -7030.0 -0.07 -0.666 -0.7643 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G19 mock treatment 411380.0 -34900.0 -0.35 524170.0 96000.0 1.01 0.4606 0.4319 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G20 mock treatment 478940.0 32700.0 0.33 405300.0 -22900.0 -0.24 0.0654 0.1598 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G21 compound treatment 465340.0 19100.0 0.19 466080.0 37900.0 0.4 0.418 0.9455 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G22 compound treatment 382750.0 -63500.0 -0.65 307440.0 -121000.0 -1.26 -1.3508 -0.9513 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G23 compound treatment 28180.0 -418000.0 -4.25 24020.0 -404000.0 -4.23 -5.9984 -1.0 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 G24 compound treatment 408960.0 -37300.0 -0.38 428840.0 683.0 0.01 -0.263 -0.6936 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H01 compound treatment 434400.0 -11900.0 -0.12 272730.0 -155000.0 -1.63 -1.2368 -0.7574 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H02 compound treatment 387040.0 -59200.0 -0.6 381010.0 -47100.0 -0.49 -0.7749 -0.9952 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H03 mock treatment 540250.0 94000.0 0.96 331940.0 -96200.0 -1.01 -0.0375 -0.027 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H04 mock treatment 286410.0 -160000.0 -1.62 396760.0 -31400.0 -0.33 -1.3813 -0.8334 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H05 compound treatment 338430.0 -108000.0 -1.1 396570.0 -31600.0 -0.33 -1.0089 -0.8813 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H06 compound treatment 445150.0 -1120.0 -0.01 368170.0 -60000.0 -0.63 -0.4525 -0.7198 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H07 compound treatment 405820.0 -40400.0 -0.41 420690.0 -7470.0 -0.08 -0.346 -0.8269 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H08 compound treatment 472320.0 26100.0 0.26 375200.0 -53000.0 -0.55 -0.2051 -0.3337 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H09 compound treatment 444390.0 -1880.0 -0.02 375770.0 -52400.0 -0.55 -0.4016 -0.7312 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H10 compound treatment 423290.0 -23000.0 -0.23 414300.0 -13900.0 -0.15 -0.2678 -0.9739 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H11 compound treatment 395700.0 -50600.0 -0.51 381380.0 -46800.0 -0.49 -0.7099 -0.9997 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H12 compound treatment 397760.0 -48500.0 -0.49 427550.0 -607.0 -0.01 -0.3531 -0.7162 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H13 compound treatment 367290.0 -79000.0 -0.8 368000.0 -60200.0 -0.63 -1.0132 -0.9929 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H14 compound treatment 366260.0 -80000.0 -0.81 451210.0 23100.0 0.24 -0.4041 -0.4765 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H15 compound treatment 482080.0 35800.0 0.36 373520.0 -54600.0 -0.57 -0.1474 -0.2174 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H16 compound treatment 460170.0 13900.0 0.14 406290.0 -21900.0 -0.23 -0.0621 -0.2307 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H17 compound treatment 365630.0 -80600.0 -0.82 479520.0 51400.0 0.54 -0.1989 -0.2029 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H18 compound treatment 468160.0 21900.0 0.22 398560.0 -29600.0 -0.31 -0.062 -0.1623 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H19 mock treatment 467630.0 21400.0 0.22 511270.0 83100.0 0.87 0.7693 0.8572 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H20 mock treatment 479040.0 32800.0 0.33 436830.0 8670.0 0.09 0.2998 0.8683 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H21 compound treatment 451610.0 5340.0 0.05 465810.0 37700.0 0.39 0.3174 0.7969 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H22 compound treatment 449280.0 3010.0 0.03 430050.0 1890.0 0.02 0.0357 0.9779 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H23 compound treatment 418330.0 -27900.0 -0.28 410690.0 -17500.0 -0.18 -0.3302 -0.9774 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 H24 compound treatment 407250.0 -39000.0 -0.4 392480.0 -35700.0 -0.37 -0.5447 -0.9996 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I01 compound treatment 323780.0 -122000.0 -1.24 415140.0 -13000.0 -0.14 -0.9766 -0.7799 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I02 compound treatment 465550.0 19300.0 0.2 340720.0 -87400.0 -0.92 -0.5092 -0.5436 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I03 compound treatment 336240.0 -110000.0 -1.12 357970.0 -70200.0 -0.74 -1.3106 -0.9793 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I04 compound treatment 257160.0 -189000.0 -1.92 344450.0 -83700.0 -0.88 -1.979 -0.9369 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I05 mock treatment 359100.0 -87200.0 -0.89 462160.0 34000.0 0.36 -0.3744 -0.3922 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I06 mock treatment 351270.0 -95000.0 -0.97 384760.0 -43400.0 -0.45 -1.0041 -0.941 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I07 compound treatment 302850.0 -143000.0 -1.46 178670.0 -249000.0 -2.61 -2.8789 -0.9619 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I08 compound treatment 457280.0 11000.0 0.11 306730.0 -121000.0 -1.27 -0.8205 -0.6424 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I09 compound treatment 481530.0 35300.0 0.36 375360.0 -52800.0 -0.55 -0.1378 -0.209 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I10 compound treatment 357080.0 -89200.0 -0.91 340000.0 -88200.0 -0.92 -1.294 -1.0 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I11 compound treatment 420580.0 -25700.0 -0.26 323910.0 -104000.0 -1.09 -0.9569 -0.8521 BCB03_000168 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I12 compound treatment 369280.0 -77000.0 -0.78 290100.0 -138000.0 -1.45 -1.576 -0.9584 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I13 compound treatment 9670.0 -437000.0 -4.44 9450.0 -419000.0 -4.39 -6.2393 -1.0 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I14 compound treatment 449440.0 3170.0 0.03 459550.0 31400.0 0.33 0.2554 0.7727 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I15 compound treatment 488520.0 42300.0 0.43 516210.0 88100.0 0.92 0.956 0.9394 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I16 compound treatment 378850.0 -67400.0 -0.69 317070.0 -111000.0 -1.16 -1.3074 -0.9681 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I17 compound treatment 420680.0 -25600.0 -0.26 484710.0 56600.0 0.59 0.2351 0.3634 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I18 compound treatment 505090.0 58800.0 0.6 435000.0 6840.0 0.07 0.4734 0.7863 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I19 compound treatment 206270.0 -240000.0 -2.44 134830.0 -293000.0 -3.07 -3.8977 -0.9934 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I20 compound treatment 442300.0 -3970.0 -0.04 414880.0 -13300.0 -0.14 -0.1269 -0.876 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I21 mock treatment 479520.0 33300.0 0.34 476690.0 48500.0 0.51 0.5985 0.9803 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I22 mock treatment 456060.0 9790.0 0.1 486520.0 58400.0 0.61 0.5028 0.8115 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I23 compound treatment 411150.0 -35100.0 -0.36 448800.0 20600.0 0.22 -0.0994 -0.2382 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 I24 compound treatment 377330.0 -68900.0 -0.7 396070.0 -32100.0 -0.34 -0.7331 -0.9434 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J01 compound treatment 379400.0 -66900.0 -0.68 437600.0 9440.0 0.1 -0.4105 -0.5978 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J02 compound treatment 388370.0 -57900.0 -0.59 387580.0 -40600.0 -0.43 -0.7167 -0.9873 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J03 compound treatment 334400.0 -112000.0 -1.14 348160.0 -80000.0 -0.84 -1.3965 -0.9888 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J04 compound treatment 329400.0 -117000.0 -1.19 328800.0 -99400.0 -1.04 -1.5759 -0.9978 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J05 mock treatment 387910.0 -58400.0 -0.59 388480.0 -39700.0 -0.42 -0.7133 -0.9849 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J06 mock treatment 369600.0 -76700.0 -0.78 354640.0 -73500.0 -0.77 -1.0956 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J07 compound treatment 458100.0 11800.0 0.12 408550.0 -19600.0 -0.21 -0.0602 -0.253 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J08 compound treatment 198530.0 -248000.0 -2.52 172320.0 -256000.0 -2.68 -3.6756 -0.9995 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J09 compound treatment 351760.0 -94500.0 -0.96 297660.0 -130000.0 -1.37 -1.6459 -0.9851 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J10 compound treatment 427220.0 -19000.0 -0.19 376010.0 -52100.0 -0.55 -0.5232 -0.9026 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J11 compound treatment 428430.0 -17800.0 -0.18 424430.0 -3730.0 -0.04 -0.1558 -0.8402 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J12 compound treatment 428240.0 -18000.0 -0.18 398200.0 -30000.0 -0.31 -0.3515 -0.9671 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J13 compound treatment 427360.0 -18900.0 -0.19 485770.0 57600.0 0.6 0.291 0.4593 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J14 compound treatment 424750.0 -21500.0 -0.22 361200.0 -67000.0 -0.7 -0.6507 -0.8855 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J15 compound treatment 322750.0 -124000.0 -1.26 391150.0 -37000.0 -0.39 -1.1617 -0.8843 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J16 compound treatment 431600.0 -14700.0 -0.15 388380.0 -39800.0 -0.42 -0.4001 -0.9039 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J17 compound treatment 411200.0 -35100.0 -0.36 408770.0 -19400.0 -0.2 -0.3956 -0.9645 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J18 compound treatment 450790.0 4520.0 0.05 428000.0 -157.0 0.0 0.0313 0.6813 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J19 compound treatment 421830.0 -24400.0 -0.25 450010.0 21900.0 0.23 -0.0137 -0.0405 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J20 compound treatment 452500.0 6230.0 0.06 401160.0 -27000.0 -0.28 -0.1552 -0.5355 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J21 mock treatment 472030.0 25800.0 0.26 470270.0 42100.0 0.44 0.4971 0.9689 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J22 mock treatment 472410.0 26100.0 0.27 457080.0 28900.0 0.3 0.4021 0.9978 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J23 compound treatment 444540.0 -1730.0 -0.02 442430.0 14300.0 0.15 0.0933 0.6199 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 J24 compound treatment 353380.0 -92900.0 -0.94 407560.0 -20600.0 -0.22 -0.8201 -0.8469 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K01 compound treatment 437320.0 -8950.0 -0.09 494300.0 66100.0 0.69 0.4257 0.6091 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K02 compound treatment 422080.0 -24200.0 -0.25 359200.0 -69000.0 -0.72 -0.6847 -0.8972 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K03 compound treatment 376800.0 -69500.0 -0.71 380720.0 -47400.0 -0.5 -0.8506 -0.9853 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K04 compound treatment 369250.0 -77000.0 -0.78 408660.0 -19500.0 -0.2 -0.6979 -0.8628 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K05 compound treatment 40200.0 -406000.0 -4.13 14880.0 -413000.0 -4.33 -5.9797 -0.9997 1107217 BCB03_000204 Cc1cccnc1I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K06 compound treatment 366520.0 -79700.0 -0.81 361280.0 -66900.0 -0.7 -1.0685 -0.9974 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K07 mock treatment 532740.0 86500.0 0.88 434270.0 6110.0 0.06 0.6667 0.7566 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K08 mock treatment 474720.0 28500.0 0.29 433760.0 5600.0 0.06 0.246 0.8337 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K09 compound treatment 522660.0 76400.0 0.78 459070.0 30900.0 0.32 0.778 0.9249 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K10 compound treatment 379780.0 -66500.0 -0.68 338480.0 -89700.0 -0.94 -1.1421 -0.9869 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K11 compound treatment 364600.0 -81700.0 -0.83 406630.0 -21500.0 -0.23 -0.7463 -0.8678 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K12 compound treatment 416970.0 -29300.0 -0.3 333440.0 -94700.0 -0.99 -0.9123 -0.8805 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K13 compound treatment 464090.0 17800.0 0.18 379680.0 -48500.0 -0.51 -0.2311 -0.4285 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K14 compound treatment 501810.0 55500.0 0.56 378480.0 -49700.0 -0.52 0.0311 0.0405 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K15 mock treatment 440270.0 -6000.0 -0.06 471200.0 43000.0 0.45 0.2758 0.6061 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K16 mock treatment 471490.0 25200.0 0.26 462260.0 34100.0 0.36 0.4339 0.9867 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K17 compound treatment 450460.0 4190.0 0.04 428750.0 593.0 0.01 0.0345 0.8017 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K18 compound treatment 505770.0 59500.0 0.6 501820.0 73700.0 0.77 0.9733 0.9927 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K19 compound treatment 610440.0 164000.0 1.67 394620.0 -33500.0 -0.35 0.9312 0.5462 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K20 compound treatment 506500.0 60200.0 0.61 373120.0 -55000.0 -0.58 0.0251 0.0298 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K21 compound treatment 482830.0 36600.0 0.37 417950.0 -10200.0 -0.11 0.1871 0.4839 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K22 compound treatment 392100.0 -54200.0 -0.55 445440.0 17300.0 0.18 -0.2612 -0.4507 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K23 mock treatment 460520.0 14300.0 0.14 498270.0 70100.0 0.73 0.6219 0.8305 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 K24 mock treatment 416110.0 -30200.0 -0.31 369440.0 -58700.0 -0.62 -0.6517 -0.9482 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L01 compound treatment 398740.0 -47500.0 -0.48 422120.0 -6040.0 -0.06 -0.3862 -0.7929 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L02 compound treatment 348640.0 -97600.0 -0.99 389370.0 -38800.0 -0.41 -0.9889 -0.9224 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L03 compound treatment 456800.0 10500.0 0.11 329840.0 -98300.0 -1.03 -0.6527 -0.6302 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L04 compound treatment 304400.0 -142000.0 -1.44 418400.0 -9760.0 -0.1 -1.0917 -0.7554 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L05 compound treatment 397880.0 -48400.0 -0.49 370190.0 -58000.0 -0.61 -0.7772 -0.9945 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L06 compound treatment 369280.0 -77000.0 -0.78 358980.0 -69200.0 -0.72 -1.0657 -0.9993 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L07 mock treatment 369820.0 -76400.0 -0.78 398450.0 -29700.0 -0.31 -0.7694 -0.9194 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L08 mock treatment 420800.0 -25500.0 -0.26 355420.0 -72700.0 -0.76 -0.7219 -0.8969 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L09 compound treatment 405440.0 -40800.0 -0.41 371380.0 -56800.0 -0.59 -0.714 -0.9845 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L10 compound treatment 385000.0 -61300.0 -0.62 412640.0 -15500.0 -0.16 -0.5552 -0.8628 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L11 compound treatment 427620.0 -18600.0 -0.19 392590.0 -35600.0 -0.37 -0.3975 -0.9508 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L12 compound treatment 328480.0 -118000.0 -1.2 397700.0 -30500.0 -0.32 -1.072 -0.8654 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L13 compound treatment 423720.0 -22500.0 -0.23 433390.0 5230.0 0.05 -0.1232 -0.5231 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L14 compound treatment 370560.0 -75700.0 -0.77 340540.0 -87600.0 -0.92 -1.1931 -0.9961 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L15 mock treatment 489210.0 42900.0 0.44 434050.0 5890.0 0.06 0.3522 0.7992 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L16 mock treatment 482590.0 36300.0 0.37 446340.0 18200.0 0.19 0.3957 0.9527 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L17 compound treatment 506370.0 60100.0 0.61 499620.0 71500.0 0.75 0.9613 0.9949 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L18 compound treatment 463700.0 17400.0 0.18 468490.0 40300.0 0.42 0.4241 0.9255 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L19 compound treatment 479840.0 33600.0 0.34 442960.0 14800.0 0.16 0.3509 0.9363 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L20 compound treatment 327900.0 -118000.0 -1.2 291050.0 -137000.0 -1.44 -1.8663 -0.9961 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L21 compound treatment 548110.0 102000.0 1.03 462500.0 34300.0 0.36 0.9863 0.9001 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L22 compound treatment 462880.0 16600.0 0.17 435860.0 7700.0 0.08 0.1764 0.9429 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L23 mock treatment 428910.0 -17400.0 -0.18 468070.0 39900.0 0.42 0.171 0.3767 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 L24 mock treatment 422590.0 -23700.0 -0.24 466960.0 38800.0 0.41 0.1173 0.2484 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M01 compound treatment 477180.0 30900.0 0.31 473380.0 45200.0 0.47 0.5572 0.9801 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M02 compound treatment 398400.0 -47900.0 -0.49 422100.0 -6060.0 -0.06 -0.3888 -0.7926 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M03 compound treatment 379560.0 -66700.0 -0.68 476440.0 48300.0 0.51 -0.1216 -0.1438 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M04 compound treatment 329680.0 -117000.0 -1.18 458280.0 30100.0 0.32 -0.6146 -0.5013 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M05 compound treatment 344960.0 -101000.0 -1.03 359090.0 -69100.0 -0.72 -1.2397 -0.9851 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M06 compound treatment 407320.0 -38900.0 -0.4 406740.0 -21400.0 -0.22 -0.4385 -0.9639 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M07 compound treatment 369480.0 -76800.0 -0.78 470620.0 42500.0 0.44 -0.2372 -0.264 3000956 BCB03_000242 CCCc1cccc(=O)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M08 compound treatment 390450.0 -55800.0 -0.57 366410.0 -61700.0 -0.65 -0.8585 -0.9979 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M09 mock treatment 471210.0 24900.0 0.25 408160.0 -20000.0 -0.21 0.0311 0.0945 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M10 mock treatment 370600.0 -75700.0 -0.77 393770.0 -34400.0 -0.36 -0.7985 -0.9403 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M11 compound treatment 436740.0 -9530.0 -0.1 478880.0 50700.0 0.53 0.3073 0.5689 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M12 compound treatment 452600.0 6330.0 0.06 469610.0 41500.0 0.43 0.3526 0.8031 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M13 mock treatment 485360.0 39100.0 0.4 480040.0 51900.0 0.54 0.6653 0.9881 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M14 mock treatment 499250.0 53000.0 0.54 420400.0 -7760.0 -0.08 0.3233 0.5936 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M15 compound treatment 458910.0 12600.0 0.13 463710.0 35600.0 0.37 0.3543 0.899 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M16 compound treatment 337470.0 -109000.0 -1.11 264870.0 -163000.0 -1.71 -1.9915 -0.9777 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M17 compound treatment 484800.0 38500.0 0.39 405440.0 -22700.0 -0.24 0.1086 0.237 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M18 compound treatment 424120.0 -22100.0 -0.23 400090.0 -28100.0 -0.29 -0.3671 -0.9913 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M19 compound treatment 463100.0 16800.0 0.17 486610.0 58500.0 0.61 0.554 0.8713 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M20 compound treatment 439860.0 -6410.0 -0.07 381160.0 -47000.0 -0.49 -0.3942 -0.7937 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M21 compound treatment 416000.0 -30300.0 -0.31 391460.0 -36700.0 -0.38 -0.4894 -0.9939 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M22 compound treatment 280800.0 -165000.0 -1.68 288080.0 -140000.0 -1.47 -2.2268 -0.9977 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M23 compound treatment 504480.0 58200.0 0.59 443860.0 15700.0 0.16 0.5346 0.8707 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 M24 compound treatment 447040.0 773.0 0.01 427140.0 -1020.0 -0.01 -0.002 -0.1494 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N01 compound treatment 373470.0 -72800.0 -0.74 454530.0 26400.0 0.28 -0.3277 -0.415 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N02 compound treatment 470810.0 24500.0 0.25 298940.0 -129000.0 -1.35 -0.781 -0.5673 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N03 compound treatment 370400.0 -75900.0 -0.77 382750.0 -45400.0 -0.48 -0.8816 -0.9731 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N04 compound treatment 382850.0 -63400.0 -0.64 340410.0 -87700.0 -0.92 -1.1058 -0.9849 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N05 compound treatment 325490.0 -121000.0 -1.23 359390.0 -68800.0 -0.72 -1.3773 -0.9678 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N06 compound treatment 234890.0 -211000.0 -2.15 265710.0 -162000.0 -1.7 -2.7224 -0.9934 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N07 compound treatment 396670.0 -49600.0 -0.5 356200.0 -72000.0 -0.75 -0.8895 -0.9808 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N08 compound treatment 334480.0 -112000.0 -1.14 350400.0 -77800.0 -0.81 -1.3793 -0.9867 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N09 mock treatment 392380.0 -53900.0 -0.55 398680.0 -29500.0 -0.31 -0.6056 -0.9633 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N10 mock treatment 459970.0 13700.0 0.14 421460.0 -6700.0 -0.07 0.0489 0.3133 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N11 compound treatment 444180.0 -2090.0 -0.02 344650.0 -83500.0 -0.87 -0.6337 -0.724 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N12 compound treatment 350520.0 -95700.0 -0.97 421490.0 -6670.0 -0.07 -0.7374 -0.7559 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N13 mock treatment 439710.0 -6560.0 -0.07 485120.0 57000.0 0.6 0.3749 0.6243 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N14 mock treatment 400170.0 -46100.0 -0.47 415940.0 -12200.0 -0.13 -0.4217 -0.8685 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N15 compound treatment 420760.0 -25500.0 -0.26 475470.0 47300.0 0.5 0.1672 0.299 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N16 compound treatment 498480.0 52200.0 0.53 506780.0 78600.0 0.82 0.9577 0.9774 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N17 compound treatment 430970.0 -15300.0 -0.16 459360.0 31200.0 0.33 0.1213 0.335 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N18 compound treatment 481200.0 34900.0 0.35 436450.0 8290.0 0.09 0.3125 0.8549 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N19 compound treatment 472810.0 26500.0 0.27 483680.0 55500.0 0.58 0.6021 0.9389 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N20 compound treatment 361350.0 -84900.0 -0.86 353470.0 -74700.0 -0.78 -1.1635 -0.9988 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N21 compound treatment 484240.0 38000.0 0.39 472270.0 44100.0 0.46 0.5997 0.996 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N22 compound treatment 329200.0 -117000.0 -1.19 385120.0 -43000.0 -0.45 -1.1601 -0.9118 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N23 compound treatment 420270.0 -26000.0 -0.26 378190.0 -50000.0 -0.52 -0.557 -0.9498 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 N24 compound treatment 411410.0 -34900.0 -0.35 464240.0 36100.0 0.38 0.0169 0.0325 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O01 compound treatment 259970.0 -186000.0 -1.89 273610.0 -155000.0 -1.62 -2.4837 -0.997 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O02 compound treatment 389000.0 -57300.0 -0.58 408360.0 -19800.0 -0.21 -0.5582 -0.9035 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O03 compound treatment 359310.0 -87000.0 -0.88 542680.0 115000.0 1.2 0.2236 0.1501 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O04 compound treatment 399810.0 -46500.0 -0.47 356850.0 -71300.0 -0.75 -0.8621 -0.9755 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O05 compound treatment 423770.0 -22500.0 -0.23 432530.0 4370.0 0.05 -0.1293 -0.5544 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O06 compound treatment 319740.0 -127000.0 -1.29 368720.0 -59400.0 -0.62 -1.3495 -0.9446 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O07 compound treatment 422240.0 -24000.0 -0.24 306500.0 -122000.0 -1.27 -1.074 -0.8275 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O08 compound treatment 343590.0 -103000.0 -1.04 258650.0 -170000.0 -1.78 -1.9936 -0.9679 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O09 compound treatment 391460.0 -54800.0 -0.56 444580.0 16400.0 0.17 -0.2722 -0.4669 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O10 compound treatment 395370.0 -50900.0 -0.52 463060.0 34900.0 0.37 -0.1071 -0.1691 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O11 mock treatment 416960.0 -29300.0 -0.3 465810.0 37700.0 0.39 0.0684 0.1383 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O12 mock treatment 467910.0 21600.0 0.22 450770.0 22600.0 0.24 0.3231 0.9993 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O13 compound treatment 443950.0 -2320.0 -0.02 454720.0 26600.0 0.28 0.1802 0.645 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O14 compound treatment 511840.0 65600.0 0.67 494320.0 66200.0 0.69 0.9614 0.9998 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O15 compound treatment 449400.0 3130.0 0.03 407630.0 -20500.0 -0.22 -0.1296 -0.5959 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O16 compound treatment 460960.0 14700.0 0.15 453530.0 25400.0 0.27 0.2936 0.9628 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O17 compound treatment 446970.0 703.0 0.01 360280.0 -67900.0 -0.71 -0.4978 -0.7 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O18 compound treatment 499300.0 53000.0 0.54 459710.0 31600.0 0.33 0.6148 0.9725 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O19 compound treatment 396250.0 -50000.0 -0.51 411840.0 -16300.0 -0.17 -0.4803 -0.8956 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O20 compound treatment 510630.0 64400.0 0.65 453610.0 25500.0 0.27 0.6511 0.9217 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O21 compound treatment 385600.0 -60700.0 -0.62 394740.0 -33400.0 -0.35 -0.6835 -0.9641 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O22 compound treatment 478880.0 32600.0 0.33 459710.0 31600.0 0.33 0.4681 1.0 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O23 compound treatment 384180.0 -62100.0 -0.63 417070.0 -11100.0 -0.12 -0.5283 -0.8235 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 O24 compound treatment 402910.0 -43400.0 -0.44 453780.0 25600.0 0.27 -0.1217 -0.2359 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P01 compound treatment 339600.0 -107000.0 -1.08 360180.0 -68000.0 -0.71 -1.2701 -0.9792 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P02 compound treatment 336550.0 -110000.0 -1.11 321280.0 -107000.0 -1.12 -1.5802 -1.0 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P03 compound treatment 257920.0 -188000.0 -1.91 315740.0 -112000.0 -1.18 -2.1863 -0.9728 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P04 compound treatment 339570.0 -107000.0 -1.08 338020.0 -90100.0 -0.94 -1.4345 -0.9976 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P05 compound treatment 326920.0 -119000.0 -1.21 321000.0 -107000.0 -1.12 -1.6515 -0.9993 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P06 compound treatment 331760.0 -115000.0 -1.16 291050.0 -137000.0 -1.44 -1.8386 -0.9945 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P07 compound treatment 272100.0 -174000.0 -1.77 334200.0 -94000.0 -0.98 -1.9476 -0.9617 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P08 compound treatment 269790.0 -176000.0 -1.79 300330.0 -128000.0 -1.34 -2.2151 -0.9897 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P09 compound treatment 382940.0 -63300.0 -0.64 350920.0 -77200.0 -0.81 -1.0273 -0.9936 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P10 compound treatment 293410.0 -153000.0 -1.55 262460.0 -166000.0 -1.74 -2.326 -0.9985 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P11 mock treatment 342010.0 -104000.0 -1.06 409380.0 -18800.0 -0.2 -0.8883 -0.8243 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P12 mock treatment 405830.0 -40400.0 -0.41 352770.0 -75400.0 -0.79 -0.8491 -0.9536 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P13 compound treatment 276010.0 -170000.0 -1.73 284690.0 -143000.0 -1.5 -2.2863 -0.9975 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P14 compound treatment 400190.0 -46100.0 -0.47 415570.0 -12600.0 -0.13 -0.4243 -0.8723 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P15 compound treatment 273080.0 -173000.0 -1.76 282050.0 -146000.0 -1.53 -2.3269 -0.9976 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P16 compound treatment 383220.0 -63000.0 -0.64 416980.0 -11200.0 -0.12 -0.5358 -0.8227 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P17 compound treatment 395850.0 -50400.0 -0.51 426400.0 -1760.0 -0.02 -0.3753 -0.732 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P18 compound treatment 276410.0 -170000.0 -1.73 274720.0 -153000.0 -1.61 -2.3573 -0.9994 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P19 compound treatment 347720.0 -98500.0 -1.0 368700.0 -59500.0 -0.62 -1.1486 -0.9739 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P20 compound treatment 325360.0 -121000.0 -1.23 342400.0 -85800.0 -0.9 -1.5041 -0.9882 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P21 compound treatment 142410.0 -304000.0 -3.09 146370.0 -282000.0 -2.95 -4.2711 -0.9997 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P22 compound treatment 393060.0 -53200.0 -0.54 331360.0 -96800.0 -1.01 -1.0995 -0.9566 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P23 compound treatment 354930.0 -91300.0 -0.93 326890.0 -101000.0 -1.06 -1.4066 -0.9978 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2281 P24 compound treatment 149930.0 -296000.0 -3.01 166270.0 -262000.0 -2.74 -4.0696 -0.9989 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A01 compound treatment 353040.0 -81700.0 -0.83 431530.0 32500.0 0.34 -0.3467 -0.3863 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A02 compound treatment 367490.0 -67300.0 -0.68 440210.0 41100.0 0.43 -0.1786 -0.2209 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A03 compound treatment 429630.0 -5140.0 -0.05 462210.0 63100.0 0.66 0.4309 0.6493 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A04 compound treatment 365530.0 -69200.0 -0.7 391090.0 -7970.0 -0.08 -0.5566 -0.7855 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A05 compound treatment 399970.0 -34800.0 -0.35 335360.0 -63700.0 -0.67 -0.722 -0.9559 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A06 compound treatment 348810.0 -86000.0 -0.87 430020.0 31000.0 0.32 -0.3883 -0.4167 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A07 compound treatment 255760.0 -179000.0 -1.82 252570.0 -146000.0 -1.53 -2.3716 -0.9964 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A08 compound treatment 300540.0 -134000.0 -1.36 365790.0 -33300.0 -0.35 -1.211 -0.8602 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A09 compound treatment 380090.0 -54700.0 -0.56 390820.0 -8240.0 -0.09 -0.4539 -0.8073 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A10 compound treatment 443440.0 8680.0 0.09 406370.0 7310.0 0.08 0.1165 0.9975 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A11 compound treatment 317920.0 -117000.0 -1.19 254720.0 -144000.0 -1.51 -1.909 -0.9928 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A12 compound treatment 390730.0 -44000.0 -0.45 370660.0 -28400.0 -0.3 -0.5269 -0.9804 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A13 mock treatment 440650.0 5890.0 0.06 381330.0 -17700.0 -0.19 -0.0891 -0.4564 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A14 mock treatment 377080.0 -57700.0 -0.59 437010.0 37900.0 0.4 -0.1334 -0.1883 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A15 compound treatment 489920.0 55200.0 0.56 386630.0 -12400.0 -0.13 0.3042 0.5287 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A16 compound treatment 376920.0 -57800.0 -0.59 371000.0 -28100.0 -0.29 -0.6236 -0.9487 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A17 compound treatment 389380.0 -45400.0 -0.46 335560.0 -63500.0 -0.67 -0.7966 -0.984 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A18 compound treatment 393770.0 -41000.0 -0.42 424180.0 25100.0 0.26 -0.1085 -0.2202 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A19 compound treatment 395360.0 -39400.0 -0.4 367520.0 -31500.0 -0.33 -0.5168 -0.9955 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A20 compound treatment 411110.0 -23700.0 -0.24 437880.0 38800.0 0.41 0.1176 0.2489 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A21 compound treatment 476400.0 41600.0 0.42 434720.0 35700.0 0.37 0.5633 0.9981 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A22 compound treatment 443570.0 8810.0 0.09 355530.0 -43500.0 -0.46 -0.2593 -0.5578 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A23 compound treatment 391010.0 -43800.0 -0.44 414000.0 14900.0 0.16 -0.2037 -0.4322 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 A24 compound treatment 340240.0 -94500.0 -0.96 406660.0 7600.0 0.08 -0.6229 -0.6463 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B01 compound treatment 342570.0 -92200.0 -0.94 289550.0 -110000.0 -1.15 -1.4738 -0.9949 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B02 compound treatment 384120.0 -50600.0 -0.51 430790.0 31700.0 0.33 -0.1289 -0.2103 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B03 compound treatment 429180.0 -5590.0 -0.06 363130.0 -35900.0 -0.38 -0.3064 -0.8046 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B04 compound treatment 326780.0 -108000.0 -1.1 378910.0 -20200.0 -0.21 -0.9253 -0.828 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B05 compound treatment 459770.0 25000.0 0.25 385780.0 -13300.0 -0.14 0.0813 0.2805 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B06 compound treatment 356840.0 -77900.0 -0.79 309760.0 -89300.0 -0.94 -1.2216 -0.9966 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B07 compound treatment 467320.0 32600.0 0.33 328430.0 -70600.0 -0.74 -0.2894 -0.357 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B08 compound treatment 433920.0 -845.0 -0.01 359320.0 -39700.0 -0.42 -0.3005 -0.7215 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B09 compound treatment 411130.0 -23600.0 -0.24 401930.0 2870.0 0.03 -0.1486 -0.6139 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B10 compound treatment 406560.0 -28200.0 -0.29 380070.0 -19000.0 -0.2 -0.3434 -0.9841 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B11 compound treatment 447130.0 12400.0 0.13 357340.0 -41700.0 -0.44 -0.2203 -0.4843 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B12 compound treatment 161440.0 -273000.0 -2.78 148670.0 -250000.0 -2.62 -3.8191 -0.9996 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B13 mock treatment 503450.0 68700.0 0.7 357120.0 -41900.0 -0.44 0.1828 0.2216 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B14 mock treatment 427800.0 -6970.0 -0.07 512210.0 113000.0 1.19 0.7882 0.6637 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B15 compound treatment 413990.0 -20800.0 -0.21 382930.0 -16100.0 -0.17 -0.2688 -0.9939 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B16 compound treatment 212050.0 -223000.0 -2.26 206440.0 -193000.0 -2.02 -3.0275 -0.9984 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B17 compound treatment 429240.0 -5530.0 -0.06 402490.0 3430.0 0.04 -0.0143 -0.2148 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B18 compound treatment 392970.0 -41800.0 -0.42 442320.0 43300.0 0.45 0.0202 0.0324 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B19 compound treatment 506720.0 72000.0 0.73 391960.0 -7100.0 -0.07 0.4644 0.6319 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B20 compound treatment 460190.0 25400.0 0.26 403950.0 4890.0 0.05 0.2189 0.8311 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B21 compound treatment 429600.0 -5170.0 -0.05 346930.0 -52100.0 -0.55 -0.4234 -0.7715 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B22 compound treatment 438650.0 3890.0 0.04 409280.0 10200.0 0.11 0.1036 0.9081 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B23 compound treatment 428430.0 -6340.0 -0.06 405530.0 6470.0 0.07 0.0024 0.0256 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 B24 compound treatment 415710.0 -19100.0 -0.19 443940.0 44900.0 0.47 0.1956 0.3846 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C01 compound treatment 393570.0 -41200.0 -0.42 315680.0 -83400.0 -0.87 -0.9138 -0.9432 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C02 compound treatment 395220.0 -39500.0 -0.4 367760.0 -31300.0 -0.33 -0.5161 -0.9949 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C03 compound treatment 367540.0 -67200.0 -0.68 337040.0 -62000.0 -0.65 -0.9426 -0.9997 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C04 compound treatment 358900.0 -75900.0 -0.77 362650.0 -36400.0 -0.38 -0.8149 -0.9474 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C05 compound treatment 353610.0 -81200.0 -0.82 302630.0 -96400.0 -1.01 -1.2976 -0.9949 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C06 compound treatment 270170.0 -165000.0 -1.67 271840.0 -127000.0 -1.33 -2.1253 -0.9937 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C07 compound treatment 374560.0 -60200.0 -0.61 310000.0 -89100.0 -0.93 -1.0925 -0.979 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C08 compound treatment 432560.0 -2210.0 -0.02 324420.0 -74600.0 -0.78 -0.5689 -0.7271 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C09 compound treatment 415060.0 -19700.0 -0.2 382080.0 -17000.0 -0.18 -0.2674 -0.9983 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C10 compound treatment 389360.0 -45400.0 -0.46 324740.0 -74300.0 -0.78 -0.8769 -0.9688 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C11 mock treatment 332320.0 -102000.0 -1.04 363430.0 -35600.0 -0.37 -1.0001 -0.9043 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C12 mock treatment 315910.0 -119000.0 -1.21 419680.0 20600.0 0.22 -0.7013 -0.5716 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C13 compound treatment 356130.0 -78600.0 -0.8 348680.0 -50400.0 -0.53 -0.9383 -0.9797 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C14 compound treatment 406720.0 -28000.0 -0.28 333120.0 -65900.0 -0.69 -0.6901 -0.9233 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C15 mock treatment 394740.0 -40000.0 -0.41 288180.0 -111000.0 -1.16 -1.1091 -0.901 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C16 mock treatment 402090.0 -32700.0 -0.33 426790.0 27700.0 0.29 -0.0294 -0.0666 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C17 compound treatment 415910.0 -18900.0 -0.19 396710.0 -2350.0 -0.02 -0.1529 -0.7916 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C18 compound treatment 446990.0 12200.0 0.12 333250.0 -65800.0 -0.69 -0.3997 -0.5705 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C19 compound treatment 394570.0 -40200.0 -0.41 370030.0 -29000.0 -0.3 -0.5039 -0.9895 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C20 compound treatment 389380.0 -45400.0 -0.46 337000.0 -62100.0 -0.65 -0.7859 -0.9858 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C21 compound treatment 435810.0 1050.0 0.01 307430.0 -91600.0 -0.96 -0.6714 -0.6992 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C22 compound treatment 418680.0 -16100.0 -0.16 396000.0 -3060.0 -0.03 -0.1383 -0.8301 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C23 compound treatment 421300.0 -13500.0 -0.14 401880.0 2820.0 0.03 -0.0759 -0.5421 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 C24 compound treatment 387900.0 -46900.0 -0.48 372240.0 -26800.0 -0.28 -0.5355 -0.9683 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D01 compound treatment 387360.0 -47400.0 -0.48 396890.0 -2170.0 -0.02 -0.3567 -0.7397 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D02 compound treatment 385250.0 -49500.0 -0.5 428040.0 29000.0 0.3 -0.1411 -0.2401 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D03 compound treatment 316050.0 -119000.0 -1.21 306720.0 -92300.0 -0.97 -1.5372 -0.994 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D04 compound treatment 413940.0 -20800.0 -0.21 374240.0 -24800.0 -0.26 -0.3336 -0.9948 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D05 compound treatment 391920.0 -42800.0 -0.44 442930.0 43900.0 0.46 0.0171 0.0271 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D06 compound treatment 419480.0 -15300.0 -0.16 431080.0 32000.0 0.34 0.1274 0.3445 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D07 compound treatment 299000.0 -136000.0 -1.38 349080.0 -50000.0 -0.52 -1.3459 -0.912 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D08 compound treatment 397920.0 -36800.0 -0.37 401540.0 2480.0 0.03 -0.2464 -0.6565 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D09 compound treatment 395200.0 -39600.0 -0.4 339070.0 -60000.0 -0.63 -0.7288 -0.9767 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D10 compound treatment 345920.0 -88800.0 -0.9 310360.0 -88700.0 -0.93 -1.2956 -0.9999 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D11 mock treatment 406010.0 -28800.0 -0.29 384350.0 -14700.0 -0.15 -0.3156 -0.9554 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D12 mock treatment 398900.0 -35900.0 -0.36 432190.0 33100.0 0.35 -0.0123 -0.0244 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D13 compound treatment 415200.0 -19600.0 -0.2 457810.0 58700.0 0.62 0.2947 0.4555 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D14 compound treatment 412770.0 -22000.0 -0.22 332120.0 -66900.0 -0.7 -0.654 -0.8884 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D15 mock treatment 513350.0 78600.0 0.8 383260.0 -15800.0 -0.17 0.4476 0.5488 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D16 mock treatment 492530.0 57800.0 0.59 501470.0 102000.0 1.07 1.1738 0.9597 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D17 compound treatment 288130.0 -147000.0 -1.49 219900.0 -179000.0 -1.88 -2.381 -0.9935 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D18 compound treatment 444450.0 9690.0 0.1 386560.0 -12500.0 -0.13 -0.023 -0.1406 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D19 compound treatment 409730.0 -25000.0 -0.25 345060.0 -54000.0 -0.57 -0.58 -0.9349 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D20 compound treatment 360240.0 -74500.0 -0.76 250920.0 -148000.0 -1.55 -1.6331 -0.9456 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D21 compound treatment 250260.0 -185000.0 -1.87 209030.0 -190000.0 -1.99 -2.7337 -0.9995 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D22 compound treatment 414820.0 -19900.0 -0.2 404960.0 5900.0 0.06 -0.0996 -0.4702 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D23 compound treatment 356970.0 -77800.0 -0.79 363520.0 -35500.0 -0.37 -0.8223 -0.941 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 D24 compound treatment 399040.0 -35700.0 -0.36 408820.0 9760.0 0.1 -0.1844 -0.489 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E01 mock treatment 405380.0 -29400.0 -0.3 458670.0 59600.0 0.62 0.2305 0.3329 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E02 mock treatment 463360.0 28600.0 0.29 388850.0 -10200.0 -0.11 0.1298 0.4192 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E03 compound treatment 398020.0 -36700.0 -0.37 323040.0 -76000.0 -0.8 -0.8273 -0.9404 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E04 compound treatment 438730.0 3970.0 0.04 472740.0 73700.0 0.77 0.5743 0.743 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E05 compound treatment 362720.0 -72000.0 -0.73 360740.0 -38300.0 -0.4 -0.8016 -0.96 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E06 compound treatment 404750.0 -30000.0 -0.31 320550.0 -78500.0 -0.82 -0.7974 -0.9088 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E07 compound treatment 427870.0 -6900.0 -0.07 371700.0 -27400.0 -0.29 -0.2523 -0.8548 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E08 compound treatment 533150.0 98400.0 1.0 499060.0 100000.0 1.05 1.4478 0.9997 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E09 mock treatment 441230.0 6470.0 0.07 429440.0 30400.0 0.32 0.2715 0.8355 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E10 mock treatment 410580.0 -24200.0 -0.25 414880.0 15800.0 0.17 -0.0566 -0.191 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E11 compound treatment 425140.0 -9630.0 -0.1 465690.0 66600.0 0.7 0.4245 0.6022 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E12 compound treatment 372870.0 -61900.0 -0.63 345380.0 -53700.0 -0.56 -0.8425 -0.9984 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E13 compound treatment 402830.0 -31900.0 -0.32 398410.0 -653.0 -0.01 -0.2343 -0.7219 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E14 compound treatment 389470.0 -45300.0 -0.46 446750.0 47700.0 0.5 0.0278 0.041 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E15 compound treatment 478650.0 43900.0 0.45 346900.0 -52200.0 -0.55 -0.0711 -0.1008 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E16 compound treatment 460700.0 25900.0 0.26 446830.0 47800.0 0.5 0.5403 0.9551 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E17 mock treatment 469060.0 34300.0 0.35 410410.0 11300.0 0.12 0.3305 0.8975 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E18 mock treatment 433630.0 -1140.0 -0.01 335040.0 -64000.0 -0.67 -0.4825 -0.7192 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E19 compound treatment 417380.0 -17400.0 -0.18 353560.0 -45500.0 -0.48 -0.462 -0.9087 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E20 compound treatment 430510.0 -4260.0 -0.04 409600.0 10500.0 0.11 0.0475 0.4005 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E21 compound treatment 367850.0 -66900.0 -0.68 417250.0 18200.0 0.19 -0.3461 -0.4901 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E22 compound treatment 444740.0 9980.0 0.1 383770.0 -15300.0 -0.16 -0.0416 -0.2195 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E23 compound treatment 374000.0 -60800.0 -0.62 441870.0 42800.0 0.45 -0.1195 -0.1566 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 E24 compound treatment 423230.0 -11500.0 -0.12 468570.0 69500.0 0.73 0.4321 0.5858 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F01 mock treatment 429690.0 -5080.0 -0.05 361930.0 -37100.0 -0.39 -0.3116 -0.7939 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F02 mock treatment 402000.0 -32800.0 -0.33 444850.0 45800.0 0.48 0.1038 0.1777 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F03 compound treatment 327790.0 -107000.0 -1.09 342290.0 -56800.0 -0.59 -1.1893 -0.9597 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F04 compound treatment 330620.0 -104000.0 -1.06 312160.0 -86900.0 -0.91 -1.3922 -0.9972 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F05 compound treatment 440320.0 5560.0 0.06 314120.0 -84900.0 -0.89 -0.5894 -0.6609 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F06 compound treatment 324270.0 -110000.0 -1.12 371610.0 -27500.0 -0.29 -0.9974 -0.8605 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F07 compound treatment 465400.0 30600.0 0.31 426080.0 27000.0 0.28 0.4203 0.9989 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F08 compound treatment 390660.0 -44100.0 -0.45 484750.0 85700.0 0.9 0.3179 0.3168 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F09 mock treatment 441230.0 6470.0 0.07 369440.0 -29600.0 -0.31 -0.173 -0.5453 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F10 mock treatment 484580.0 49800.0 0.51 366140.0 -32900.0 -0.34 0.114 0.1862 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F11 compound treatment 322900.0 -112000.0 -1.14 270720.0 -128000.0 -1.34 -1.7547 -0.9965 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F12 compound treatment 329390.0 -105000.0 -1.07 333440.0 -65600.0 -0.69 -1.2434 -0.9771 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F13 compound treatment 460610.0 25800.0 0.26 351850.0 -47200.0 -0.49 -0.1641 -0.293 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F14 compound treatment 493810.0 59000.0 0.6 362520.0 -36500.0 -0.38 0.1535 0.2157 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F15 compound treatment 466810.0 32000.0 0.33 409440.0 10400.0 0.11 0.3071 0.8946 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F16 compound treatment 444690.0 9930.0 0.1 365250.0 -33800.0 -0.35 -0.1792 -0.4865 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F17 mock treatment 497950.0 63200.0 0.64 324280.0 -74800.0 -0.78 -0.1 -0.0987 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F18 mock treatment 462660.0 27900.0 0.28 406560.0 7500.0 0.08 0.256 0.8702 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F19 compound treatment 488700.0 53900.0 0.55 307230.0 -91800.0 -0.96 -0.2928 -0.2644 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F20 compound treatment 367260.0 -67500.0 -0.69 301500.0 -97600.0 -1.02 -1.2079 -0.9812 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F21 compound treatment 402770.0 -32000.0 -0.33 401460.0 2400.0 0.03 -0.2121 -0.6506 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F22 compound treatment 414990.0 -19800.0 -0.2 431710.0 32600.0 0.34 0.0998 0.2515 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F23 compound treatment 401020.0 -33700.0 -0.34 429070.0 30000.0 0.31 -0.0202 -0.0434 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 F24 compound treatment 316000.0 -119000.0 -1.21 379100.0 -20000.0 -0.21 -1.0013 -0.8175 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G01 compound treatment 356960.0 -77800.0 -0.79 328070.0 -71000.0 -0.74 -1.0851 -0.9995 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G02 compound treatment 460970.0 26200.0 0.27 434570.0 35500.0 0.37 0.4514 0.9866 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G03 mock treatment 439760.0 5000.0 0.05 447360.0 48300.0 0.51 0.3937 0.7742 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G04 mock treatment 396440.0 -38300.0 -0.39 421370.0 22300.0 0.23 -0.1101 -0.2425 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G05 compound treatment 429960.0 -4810.0 -0.05 299210.0 -99900.0 -1.05 -0.7743 -0.7393 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G06 compound treatment 392690.0 -42100.0 -0.43 348740.0 -50300.0 -0.53 -0.6752 -0.9946 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G07 compound treatment 546450.0 112000.0 1.13 332670.0 -66400.0 -0.7 0.3106 0.2334 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G08 compound treatment 436030.0 1270.0 0.01 423240.0 24200.0 0.25 0.1882 0.742 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G09 compound treatment 439300.0 4540.0 0.05 388000.0 -11100.0 -0.12 -0.0494 -0.3958 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G10 compound treatment 337530.0 -97200.0 -0.99 297990.0 -101000.0 -1.06 -1.4475 -0.9994 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G11 compound treatment 415120.0 -19600.0 -0.2 344320.0 -54700.0 -0.57 -0.5467 -0.9002 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G12 compound treatment 460680.0 25900.0 0.26 321500.0 -77600.0 -0.81 -0.3884 -0.4547 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G13 compound treatment 436610.0 1850.0 0.02 331590.0 -67500.0 -0.71 -0.4866 -0.6881 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G14 compound treatment 501630.0 66900.0 0.68 419930.0 20900.0 0.22 0.6351 0.8897 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G15 compound treatment 505920.0 71200.0 0.72 349920.0 -49100.0 -0.51 0.1472 0.1658 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G16 compound treatment 444750.0 9990.0 0.1 421650.0 22600.0 0.24 0.2391 0.9285 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G17 compound treatment 404400.0 -30400.0 -0.31 373050.0 -26000.0 -0.27 -0.4109 -0.9981 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G18 compound treatment 452260.0 17500.0 0.18 397120.0 -1940.0 -0.02 0.1113 0.6221 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G19 mock treatment 469890.0 35100.0 0.36 401020.0 1960.0 0.02 0.2669 0.7465 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G20 mock treatment 476640.0 41900.0 0.43 424760.0 25700.0 0.27 0.4913 0.9756 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G21 compound treatment 454050.0 19300.0 0.2 390460.0 -8600.0 -0.09 0.0748 0.3469 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G22 compound treatment 436720.0 1960.0 0.02 442000.0 42900.0 0.45 0.3322 0.7376 3071255 BCB03_000457 NC(=N)NCC#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G23 compound treatment 422750.0 -12000.0 -0.12 417040.0 18000.0 0.19 0.0468 0.2087 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 G24 compound treatment 395360.0 -39400.0 -0.4 471810.0 72700.0 0.76 0.2558 0.2971 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H01 compound treatment 333060.0 -102000.0 -1.03 333480.0 -65600.0 -0.69 -1.2167 -0.9803 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H02 compound treatment 454980.0 20200.0 0.21 473440.0 74400.0 0.78 0.6963 0.864 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H03 mock treatment 410520.0 -24200.0 -0.25 324440.0 -74600.0 -0.78 -0.7271 -0.8869 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H04 mock treatment 511950.0 77200.0 0.78 435710.0 36600.0 0.38 0.8261 0.946 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H05 compound treatment 462330.0 27600.0 0.28 300480.0 -98600.0 -1.03 -0.5323 -0.4974 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H06 compound treatment 452000.0 17200.0 0.18 380590.0 -18500.0 -0.19 -0.013 -0.0499 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H07 compound treatment 483590.0 48800.0 0.5 434000.0 34900.0 0.37 0.6097 0.9888 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H08 compound treatment 412390.0 -22400.0 -0.23 416910.0 17800.0 0.19 -0.0286 -0.097 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H09 compound treatment 17450.0 -417000.0 -4.24 12750.0 -386000.0 -4.05 -5.8608 -0.9997 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H10 compound treatment 433690.0 -1080.0 -0.01 294790.0 -104000.0 -1.09 -0.7803 -0.7141 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H11 compound treatment 244160.0 -191000.0 -1.94 175360.0 -224000.0 -2.34 -3.027 -0.9955 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H12 compound treatment 309890.0 -125000.0 -1.27 296090.0 -103000.0 -1.08 -1.6602 -0.9967 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H13 compound treatment 458950.0 24200.0 0.25 338020.0 -61000.0 -0.64 -0.2785 -0.4064 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H14 compound treatment 454880.0 20100.0 0.2 453850.0 54800.0 0.57 0.5504 0.9033 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H15 compound treatment 442080.0 7320.0 0.07 392700.0 -6360.0 -0.07 0.0054 0.0543 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H16 compound treatment 475770.0 41000.0 0.42 374080.0 -25000.0 -0.26 0.1096 0.2226 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H17 compound treatment 412490.0 -22300.0 -0.23 344480.0 -54600.0 -0.57 -0.5645 -0.9177 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H18 compound treatment 418880.0 -15900.0 -0.16 401690.0 2630.0 0.03 -0.0947 -0.5782 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H19 mock treatment 458000.0 23200.0 0.24 375290.0 -23800.0 -0.25 -0.0092 -0.0267 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H20 mock treatment 450570.0 15800.0 0.16 448180.0 49100.0 0.51 0.4775 0.8857 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H21 compound treatment 333490.0 -101000.0 -1.03 371200.0 -27900.0 -0.29 -0.9342 -0.8732 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H22 compound treatment 457870.0 23100.0 0.23 420480.0 21400.0 0.22 0.3247 0.9997 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H23 compound treatment 411210.0 -23600.0 -0.24 444580.0 45500.0 0.48 0.168 0.3148 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 H24 compound treatment 423110.0 -11700.0 -0.12 370560.0 -28500.0 -0.3 -0.2949 -0.918 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I01 compound treatment 375750.0 -59000.0 -0.6 386810.0 -12300.0 -0.13 -0.5148 -0.8395 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I02 compound treatment 380450.0 -54300.0 -0.55 409990.0 10900.0 0.11 -0.3093 -0.5488 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I03 compound treatment 504100.0 69300.0 0.7 443400.0 44300.0 0.46 0.8267 0.9796 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I04 compound treatment 427520.0 -7250.0 -0.07 347430.0 -51600.0 -0.54 -0.4346 -0.796 1035256 BCB03_000483 C#CCNCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I05 mock treatment 384020.0 -50700.0 -0.52 261180.0 -138000.0 -1.44 -1.3862 -0.9037 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I06 mock treatment 418450.0 -16300.0 -0.17 373530.0 -25500.0 -0.27 -0.3064 -0.9735 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I07 compound treatment 320000.0 -115000.0 -1.17 324800.0 -74300.0 -0.78 -1.3749 -0.9806 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I08 compound treatment 352330.0 -82400.0 -0.84 439120.0 40100.0 0.42 -0.2956 -0.3155 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I09 compound treatment 348960.0 -85800.0 -0.87 473300.0 74200.0 0.78 -0.0666 -0.057 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I10 compound treatment 382830.0 -51900.0 -0.53 435360.0 36300.0 0.38 -0.1043 -0.1603 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I11 compound treatment 408260.0 -26500.0 -0.27 282510.0 -117000.0 -1.22 -1.054 -0.8428 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I12 compound treatment 368000.0 -66800.0 -0.68 399480.0 417.0 0.0 -0.4767 -0.7025 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I13 compound treatment 499710.0 64900.0 0.66 449840.0 50800.0 0.53 0.8429 0.9943 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I14 compound treatment 411420.0 -23300.0 -0.24 365530.0 -33500.0 -0.35 -0.4162 -0.9817 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I15 compound treatment 435040.0 275.0 0.0 219950.0 -179000.0 -1.88 -1.325 -0.7061 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I16 compound treatment 398430.0 -36300.0 -0.37 347850.0 -51200.0 -0.54 -0.6405 -0.9834 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I17 compound treatment 371430.0 -63300.0 -0.64 343810.0 -55300.0 -0.58 -0.8645 -0.9986 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I18 compound treatment 491940.0 57200.0 0.58 417890.0 18800.0 0.2 0.5503 0.8969 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I19 compound treatment 391170.0 -43600.0 -0.44 420130.0 21100.0 0.22 -0.1572 -0.3176 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I20 compound treatment 464410.0 29600.0 0.3 395130.0 -3930.0 -0.04 0.1839 0.6047 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I21 mock treatment 419040.0 -15700.0 -0.16 410400.0 11300.0 0.12 -0.029 -0.1457 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I22 mock treatment 428100.0 -6670.0 -0.07 393600.0 -5460.0 -0.06 -0.0884 -0.9965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I23 compound treatment 356240.0 -78500.0 -0.8 377730.0 -21300.0 -0.22 -0.7223 -0.8716 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 I24 compound treatment 414880.0 -19900.0 -0.2 433250.0 34200.0 0.36 0.1104 0.2684 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J01 compound treatment 382950.0 -51800.0 -0.53 353720.0 -45300.0 -0.48 -0.7083 -0.9987 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J02 compound treatment 407730.0 -27000.0 -0.27 384680.0 -14400.0 -0.15 -0.3008 -0.96 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J03 compound treatment 323140.0 -112000.0 -1.13 443880.0 44800.0 0.47 -0.4701 -0.3829 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J04 compound treatment 321060.0 -114000.0 -1.16 296170.0 -103000.0 -1.08 -1.5794 -0.9994 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J05 mock treatment 491530.0 56800.0 0.58 330270.0 -68800.0 -0.72 -0.1018 -0.1102 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J06 mock treatment 398790.0 -36000.0 -0.37 370400.0 -28700.0 -0.3 -0.4709 -0.9952 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J07 compound treatment 267380.0 -167000.0 -1.7 272690.0 -126000.0 -1.32 -2.139 -0.9923 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J08 compound treatment 418450.0 -16300.0 -0.17 365050.0 -34000.0 -0.36 -0.3692 -0.9394 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J09 compound treatment 371650.0 -63100.0 -0.64 286890.0 -112000.0 -1.18 -1.2846 -0.9594 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J10 compound treatment 410210.0 -24600.0 -0.25 381310.0 -17800.0 -0.19 -0.308 -0.9895 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J11 compound treatment 367230.0 -67500.0 -0.69 326490.0 -72600.0 -0.76 -1.023 -0.9987 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J12 compound treatment 444530.0 9770.0 0.1 437480.0 38400.0 0.4 0.3548 0.8558 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J13 compound treatment 309120.0 -126000.0 -1.28 361620.0 -37400.0 -0.39 -1.1803 -0.8836 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J14 compound treatment 482850.0 48100.0 0.49 435520.0 36500.0 0.38 0.6156 0.9926 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J15 compound treatment 208480.0 -226000.0 -2.3 175110.0 -224000.0 -2.35 -3.2852 -0.9999 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J16 compound treatment 460770.0 26000.0 0.26 449160.0 50100.0 0.52 0.558 0.9496 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J17 compound treatment 362890.0 -71900.0 -0.73 405790.0 6730.0 0.07 -0.4666 -0.6359 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J18 compound treatment 444930.0 10200.0 0.1 438030.0 39000.0 0.41 0.3617 0.8589 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J19 compound treatment 196490.0 -238000.0 -2.42 233810.0 -165000.0 -1.73 -2.9365 -0.9865 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J20 compound treatment 445010.0 10200.0 0.1 419200.0 20100.0 0.21 0.2228 0.947 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J21 mock treatment 446830.0 12100.0 0.12 411490.0 12400.0 0.13 0.1788 0.9995 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J22 mock treatment 421380.0 -13400.0 -0.14 415370.0 16300.0 0.17 0.0246 0.1128 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J23 compound treatment 382930.0 -51800.0 -0.53 390610.0 -8450.0 -0.09 -0.4351 -0.8146 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 J24 compound treatment 422350.0 -12400.0 -0.13 409210.0 10100.0 0.11 -0.014 -0.0851 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K01 compound treatment 300570.0 -134000.0 -1.36 195090.0 -204000.0 -2.14 -2.4755 -0.9765 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K02 compound treatment 401920.0 -32800.0 -0.33 452750.0 53700.0 0.56 0.1617 0.2473 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K03 compound treatment 474150.0 39400.0 0.4 349200.0 -49900.0 -0.52 -0.0864 -0.1313 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K04 compound treatment 471440.0 36700.0 0.37 309310.0 -89800.0 -0.94 -0.4014 -0.3968 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K05 compound treatment 362840.0 -71900.0 -0.73 253040.0 -146000.0 -1.53 -1.5987 -0.9428 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K06 compound treatment 438040.0 3280.0 0.03 358570.0 -40500.0 -0.42 -0.2765 -0.6496 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K07 mock treatment 495640.0 60900.0 0.62 337050.0 -62000.0 -0.65 -0.022 -0.0245 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K08 mock treatment 454980.0 20200.0 0.21 433160.0 34100.0 0.36 0.3979 0.9655 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K09 compound treatment 347600.0 -87200.0 -0.89 341940.0 -57100.0 -0.6 -1.0496 -0.9818 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K10 compound treatment 296110.0 -139000.0 -1.41 407550.0 8490.0 0.09 -0.9335 -0.6612 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K11 compound treatment 327050.0 -108000.0 -1.09 408070.0 9010.0 0.09 -0.7073 -0.6438 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K12 compound treatment 418720.0 -16000.0 -0.16 328180.0 -70900.0 -0.74 -0.6404 -0.8423 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K13 compound treatment 269930.0 -165000.0 -1.68 203210.0 -196000.0 -2.05 -2.6355 -0.9949 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K14 compound treatment 435300.0 535.0 0.01 426460.0 27400.0 0.29 0.2068 0.7204 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K15 mock treatment 507630.0 72900.0 0.74 388290.0 -10800.0 -0.11 0.4438 0.5925 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K16 mock treatment 418030.0 -16700.0 -0.17 378270.0 -20800.0 -0.22 -0.2743 -0.9925 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K17 compound treatment 531650.0 96900.0 0.98 423360.0 24300.0 0.25 0.8762 0.8616 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K18 compound treatment 469840.0 35100.0 0.36 475300.0 76200.0 0.8 0.8169 0.9339 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K19 compound treatment 504000.0 69200.0 0.7 457920.0 58900.0 0.62 0.9336 0.9978 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K20 compound treatment 415840.0 -18900.0 -0.19 420450.0 21400.0 0.22 0.0225 0.0761 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K21 compound treatment 466490.0 31700.0 0.32 492980.0 93900.0 0.98 0.9238 0.8921 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K22 compound treatment 507320.0 72600.0 0.74 453280.0 54200.0 0.57 0.923 0.9917 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K23 mock treatment 423740.0 -11000.0 -0.11 442180.0 43100.0 0.45 0.2402 0.5161 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 K24 mock treatment 410400.0 -24400.0 -0.25 373180.0 -25900.0 -0.27 -0.3668 -0.999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L01 compound treatment 408810.0 -26000.0 -0.26 348510.0 -50600.0 -0.53 -0.561 -0.9482 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L02 compound treatment 418100.0 -16700.0 -0.17 395750.0 -3310.0 -0.03 -0.1443 -0.8347 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L03 compound treatment 311850.0 -123000.0 -1.25 336380.0 -62700.0 -0.66 -1.3476 -0.9549 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L04 compound treatment 320110.0 -115000.0 -1.17 314010.0 -85100.0 -0.89 -1.454 -0.9912 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L05 compound treatment 424070.0 -10700.0 -0.11 289320.0 -110000.0 -1.15 -0.8899 -0.7705 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L06 compound treatment 433380.0 -1390.0 -0.01 306510.0 -92600.0 -0.97 -0.6957 -0.7173 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L07 mock treatment 364560.0 -70200.0 -0.71 260130.0 -139000.0 -1.46 -1.5338 -0.9461 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L08 mock treatment 353560.0 -81200.0 -0.83 353050.0 -46000.0 -0.48 -0.9244 -0.9672 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L09 compound treatment 421020.0 -13700.0 -0.14 297650.0 -101000.0 -1.06 -0.8501 -0.7932 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L10 compound treatment 392000.0 -42800.0 -0.43 351380.0 -47700.0 -0.5 -0.6606 -0.9976 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L11 compound treatment 374080.0 -60700.0 -0.62 318560.0 -80500.0 -0.84 -1.0325 -0.9882 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L12 compound treatment 446760.0 12000.0 0.12 268670.0 -130000.0 -1.37 -0.8799 -0.6415 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L13 compound treatment 332870.0 -102000.0 -1.04 355600.0 -43500.0 -0.46 -1.0542 -0.9319 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L14 compound treatment 460240.0 25500.0 0.26 335870.0 -63200.0 -0.66 -0.2851 -0.4011 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L15 mock treatment 489040.0 54300.0 0.55 439120.0 40100.0 0.42 0.6868 0.9909 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L16 mock treatment 470940.0 36200.0 0.37 379100.0 -20000.0 -0.21 0.112 0.2649 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L17 compound treatment 405190.0 -29600.0 -0.3 371260.0 -27800.0 -0.29 -0.4185 -0.9999 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L18 compound treatment 471090.0 36300.0 0.37 447850.0 48800.0 0.51 0.6225 0.9872 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L19 compound treatment 391740.0 -43000.0 -0.44 436680.0 37600.0 0.39 -0.0305 -0.0518 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L20 compound treatment 399520.0 -35200.0 -0.36 398470.0 -593.0 -0.01 -0.2577 -0.7193 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L21 compound treatment 372100.0 -62700.0 -0.64 396580.0 -2480.0 -0.03 -0.4687 -0.7354 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L22 compound treatment 418560.0 -16200.0 -0.16 404220.0 5160.0 0.05 -0.0782 -0.4514 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L23 mock treatment 443730.0 8970.0 0.09 467950.0 68900.0 0.72 0.5748 0.7901 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 L24 mock treatment 414110.0 -20700.0 -0.21 403450.0 4390.0 0.05 -0.1159 -0.5395 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M01 compound treatment 460100.0 25300.0 0.26 483370.0 84300.0 0.88 0.8067 0.8767 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M02 compound treatment 511120.0 76400.0 0.78 434560.0 35500.0 0.37 0.8116 0.9433 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M03 compound treatment 354990.0 -79800.0 -0.81 338080.0 -61000.0 -0.64 -1.025 -0.9931 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M04 compound treatment 369990.0 -64800.0 -0.66 374330.0 -24700.0 -0.26 -0.6487 -0.917 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M05 compound treatment 400930.0 -33800.0 -0.34 318690.0 -80400.0 -0.84 -0.8386 -0.9219 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M06 compound treatment 431690.0 -3080.0 -0.03 372860.0 -26200.0 -0.27 -0.2162 -0.7825 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M07 compound treatment 441300.0 6540.0 0.07 311940.0 -87100.0 -0.91 -0.5985 -0.6539 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M08 compound treatment 386890.0 -47900.0 -0.49 401980.0 2920.0 0.03 -0.3224 -0.6614 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M09 mock treatment 376090.0 -58700.0 -0.6 392840.0 -6220.0 -0.07 -0.4677 -0.7798 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M10 mock treatment 467460.0 32700.0 0.33 377530.0 -21500.0 -0.23 0.0754 0.1877 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M11 compound treatment 391870.0 -42900.0 -0.44 427550.0 28500.0 0.3 -0.0972 -0.1839 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M12 compound treatment 483580.0 48800.0 0.5 416480.0 17400.0 0.18 0.4798 0.9078 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M13 mock treatment 468740.0 34000.0 0.35 406950.0 7890.0 0.08 0.3026 0.8523 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M14 mock treatment 444160.0 9400.0 0.1 469050.0 70000.0 0.73 0.586 0.7925 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M15 compound treatment 423850.0 -10900.0 -0.11 413860.0 14800.0 0.16 0.0312 0.1636 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M16 compound treatment 507130.0 72400.0 0.74 474760.0 75700.0 0.79 1.0808 0.9993 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M17 compound treatment 460990.0 26200.0 0.27 406030.0 6970.0 0.07 0.2401 0.8688 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M18 compound treatment 474240.0 39500.0 0.4 391290.0 -7770.0 -0.08 0.2261 0.5523 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M19 compound treatment 478670.0 43900.0 0.45 372330.0 -26700.0 -0.28 0.1174 0.2229 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M20 compound treatment 442040.0 7280.0 0.07 481690.0 82600.0 0.87 0.6644 0.7647 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M21 compound treatment 355090.0 -79700.0 -0.81 431760.0 32700.0 0.34 -0.3303 -0.3757 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M22 compound treatment 469760.0 35000.0 0.36 456220.0 57200.0 0.6 0.6749 0.969 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M23 compound treatment 483360.0 48600.0 0.49 444660.0 45600.0 0.48 0.687 0.9999 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 M24 compound treatment 381980.0 -52800.0 -0.54 400650.0 1590.0 0.02 -0.3675 -0.6849 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N01 compound treatment 302610.0 -132000.0 -1.34 362750.0 -36300.0 -0.38 -1.2187 -0.8731 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N02 compound treatment 394650.0 -40100.0 -0.41 464960.0 65900.0 0.69 0.2 0.2494 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N03 compound treatment 390280.0 -44500.0 -0.45 270310.0 -129000.0 -1.35 -1.2736 -0.8951 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N04 compound treatment 345600.0 -89200.0 -0.91 360490.0 -38600.0 -0.4 -0.9265 -0.9338 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N05 compound treatment 344920.0 -89800.0 -0.91 300600.0 -98500.0 -1.03 -1.3751 -0.9981 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N06 compound treatment 68000.0 -367000.0 -3.73 118600.0 -280000.0 -2.94 -4.7133 -0.9931 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N07 compound treatment 257860.0 -177000.0 -1.8 224170.0 -175000.0 -1.83 -2.5669 -1.0 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N08 compound treatment 321090.0 -114000.0 -1.16 295310.0 -104000.0 -1.09 -1.5855 -0.9995 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N09 mock treatment 477650.0 42900.0 0.44 359240.0 -39800.0 -0.42 0.0131 0.0217 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N10 mock treatment 483160.0 48400.0 0.49 388640.0 -10400.0 -0.11 0.2705 0.537 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N11 compound treatment 247300.0 -187000.0 -1.91 190720.0 -208000.0 -2.18 -2.8906 -0.9977 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N12 compound treatment 178340.0 -256000.0 -2.61 185720.0 -213000.0 -2.24 -3.4232 -0.9971 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N13 mock treatment 451060.0 16300.0 0.17 385300.0 -13800.0 -0.14 0.0151 0.0689 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N14 mock treatment 413280.0 -21500.0 -0.22 426160.0 27100.0 0.28 0.0464 0.1295 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N15 compound treatment 275540.0 -159000.0 -1.62 269350.0 -130000.0 -1.36 -2.1052 -0.9962 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N16 compound treatment 300960.0 -134000.0 -1.36 267420.0 -132000.0 -1.38 -1.9368 -1.0 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N17 compound treatment 226260.0 -209000.0 -2.12 201930.0 -197000.0 -2.07 -2.9588 -0.9999 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N18 compound treatment 138350.0 -296000.0 -3.01 110020.0 -289000.0 -3.03 -4.2714 -1.0 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N19 compound treatment 228990.0 -206000.0 -2.09 191310.0 -208000.0 -2.18 -3.0178 -0.9998 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N20 compound treatment 219590.0 -215000.0 -2.19 208970.0 -190000.0 -1.99 -2.9545 -0.9989 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N21 compound treatment 294810.0 -140000.0 -1.42 240280.0 -159000.0 -1.66 -2.1821 -0.997 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N22 compound treatment 288700.0 -146000.0 -1.48 252820.0 -146000.0 -1.53 -2.1331 -0.9999 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N23 compound treatment 427370.0 -7400.0 -0.08 373410.0 -25700.0 -0.27 -0.2432 -0.8714 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 N24 compound treatment 365120.0 -69600.0 -0.71 386200.0 -12900.0 -0.13 -0.5957 -0.8269 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O01 compound treatment 378960.0 -55800.0 -0.57 346300.0 -52800.0 -0.55 -0.7919 -0.9999 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O02 compound treatment 411940.0 -22800.0 -0.23 465990.0 66900.0 0.7 0.3318 0.4493 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O03 compound treatment 396010.0 -38800.0 -0.39 453980.0 54900.0 0.58 0.1284 0.1841 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O04 compound treatment 364510.0 -70300.0 -0.71 418500.0 19400.0 0.2 -0.3608 -0.486 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O05 compound treatment 373130.0 -61600.0 -0.63 356090.0 -43000.0 -0.45 -0.7613 -0.9869 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O06 compound treatment 406960.0 -27800.0 -0.28 348280.0 -50800.0 -0.53 -0.576 -0.9562 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O07 compound treatment 431730.0 -3040.0 -0.03 349290.0 -49800.0 -0.52 -0.3906 -0.7476 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O08 compound treatment 390630.0 -44100.0 -0.45 405680.0 6620.0 0.07 -0.2681 -0.5908 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O09 compound treatment 439870.0 5110.0 0.05 320260.0 -78800.0 -0.83 -0.5471 -0.6614 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O10 compound treatment 465920.0 31200.0 0.32 481070.0 82000.0 0.86 0.8314 0.908 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O11 mock treatment 449860.0 15100.0 0.15 379650.0 -19400.0 -0.2 -0.0354 -0.1388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O12 mock treatment 463200.0 28400.0 0.29 444450.0 45400.0 0.48 0.5406 0.9715 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O13 compound treatment 432640.0 -2130.0 -0.02 453980.0 54900.0 0.58 0.3916 0.6801 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O14 compound treatment 469370.0 34600.0 0.35 498660.0 99600.0 1.04 0.9865 0.8959 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O15 compound treatment 472320.0 37600.0 0.38 458940.0 59900.0 0.63 0.7135 0.9716 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O16 compound treatment 512520.0 77800.0 0.79 421760.0 22700.0 0.24 0.7269 0.8809 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O17 compound treatment 446560.0 11800.0 0.12 421040.0 22000.0 0.23 0.2476 0.9537 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O18 compound treatment 469120.0 34400.0 0.35 454910.0 55800.0 0.59 0.6606 0.9695 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O19 compound treatment 381850.0 -52900.0 -0.54 347700.0 -51400.0 -0.54 -0.7608 -1.0 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O20 compound treatment 476180.0 41400.0 0.42 413150.0 14100.0 0.15 0.402 0.9013 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O21 compound treatment 461810.0 27000.0 0.27 395080.0 -3980.0 -0.04 0.1648 0.5929 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O22 compound treatment 445140.0 10400.0 0.11 431210.0 32100.0 0.34 0.3127 0.8861 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O23 compound treatment 415300.0 -19500.0 -0.2 410040.0 11000.0 0.12 -0.0585 -0.2559 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 O24 compound treatment 407430.0 -27300.0 -0.28 413640.0 14600.0 0.15 -0.0884 -0.2789 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P01 compound treatment 296970.0 -138000.0 -1.4 304320.0 -94700.0 -0.99 -1.6921 -0.9858 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P02 compound treatment 361120.0 -73600.0 -0.75 323680.0 -75400.0 -0.79 -1.0877 -0.9996 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P03 compound treatment 288930.0 -146000.0 -1.48 254530.0 -145000.0 -1.51 -2.1187 -0.9999 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P04 compound treatment 294530.0 -140000.0 -1.43 322520.0 -76500.0 -0.8 -1.5748 -0.963 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P05 compound treatment 286280.0 -148000.0 -1.51 261300.0 -138000.0 -1.44 -2.0876 -0.9998 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P06 compound treatment 327700.0 -107000.0 -1.09 258880.0 -140000.0 -1.47 -1.8079 -0.9891 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P07 compound treatment 182790.0 -252000.0 -2.56 183910.0 -215000.0 -2.25 -3.4046 -0.998 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P08 compound treatment 319400.0 -115000.0 -1.17 267290.0 -132000.0 -1.38 -1.8052 -0.9967 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P09 compound treatment 218090.0 -217000.0 -2.2 235870.0 -163000.0 -1.71 -2.766 -0.9922 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P10 compound treatment 358250.0 -76500.0 -0.78 327300.0 -71800.0 -0.75 -1.0815 -0.9999 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P11 mock treatment 331040.0 -104000.0 -1.05 337150.0 -61900.0 -0.65 -1.204 -0.9728 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P12 mock treatment 384810.0 -50000.0 -0.51 399460.0 397.0 0.0 -0.356 -0.7013 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P13 compound treatment 186920.0 -248000.0 -2.52 182030.0 -217000.0 -2.27 -3.3889 -0.9987 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P14 compound treatment 247840.0 -187000.0 -1.9 266420.0 -133000.0 -1.39 -2.3259 -0.9882 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P15 compound treatment 298880.0 -136000.0 -1.38 252260.0 -147000.0 -1.54 -2.0641 -0.9986 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P16 compound treatment 336830.0 -97900.0 -1.0 338780.0 -60300.0 -0.63 -1.1504 -0.9759 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P17 compound treatment 161450.0 -273000.0 -2.78 138820.0 -260000.0 -2.73 -3.892 -1.0 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P18 compound treatment 352220.0 -82500.0 -0.84 341390.0 -57700.0 -0.6 -1.0204 -0.987 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P19 compound treatment 234190.0 -201000.0 -2.04 228120.0 -171000.0 -1.79 -2.7077 -0.9979 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P20 compound treatment 380970.0 -53800.0 -0.55 398040.0 -1020.0 -0.01 -0.3941 -0.7208 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P21 compound treatment 279120.0 -156000.0 -1.58 226150.0 -173000.0 -1.81 -2.3995 -0.9977 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P22 compound treatment 389200.0 -45600.0 -0.46 410750.0 11700.0 0.12 -0.2408 -0.5028 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P23 compound treatment 256810.0 -178000.0 -1.81 235310.0 -164000.0 -1.72 -2.4919 -0.9997 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2282 P24 compound treatment 392430.0 -42300.0 -0.43 341570.0 -57500.0 -0.6 -0.7302 -0.9864 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A01 compound treatment 402240.0 -63100.0 -0.64 457090.0 -11100.0 -0.12 -0.5357 -0.8216 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A02 compound treatment 461470.0 -3910.0 -0.04 414140.0 -54000.0 -0.57 -0.4283 -0.7549 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A03 compound treatment 431840.0 -33500.0 -0.34 469760.0 1600.0 0.02 -0.2291 -0.6714 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A04 compound treatment 434840.0 -30500.0 -0.31 460160.0 -8000.0 -0.08 -0.2787 -0.867 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A05 compound treatment 463270.0 -2110.0 -0.02 442410.0 -25700.0 -0.27 -0.2059 -0.7609 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A06 compound treatment 373920.0 -91500.0 -0.93 442290.0 -25900.0 -0.27 -0.8488 -0.8768 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A07 compound treatment 434350.0 -31000.0 -0.32 404000.0 -64200.0 -0.67 -0.6983 -0.9405 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A08 compound treatment 356920.0 -108000.0 -1.1 430140.0 -38000.0 -0.4 -1.061 -0.9053 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A09 compound treatment 406080.0 -59300.0 -0.6 344450.0 -124000.0 -1.3 -1.3426 -0.9393 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A10 compound treatment 342360.0 -123000.0 -1.25 411310.0 -56800.0 -0.6 -1.3051 -0.9425 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A11 compound treatment 356070.0 -109000.0 -1.11 448420.0 -19700.0 -0.21 -0.9317 -0.8246 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A12 compound treatment 377340.0 -88000.0 -0.89 370960.0 -97200.0 -1.02 -1.3527 -0.9979 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A13 mock treatment 483390.0 18000.0 0.18 413440.0 -54700.0 -0.57 -0.276 -0.4586 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A14 mock treatment 445470.0 -19900.0 -0.2 440040.0 -28100.0 -0.29 -0.3514 -0.9832 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A15 compound treatment 425010.0 -40400.0 -0.41 419200.0 -49000.0 -0.51 -0.6528 -0.9939 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A16 compound treatment 458310.0 -7070.0 -0.07 336500.0 -132000.0 -1.38 -1.0262 -0.7429 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A17 compound treatment 332100.0 -133000.0 -1.35 374410.0 -93700.0 -0.98 -1.6522 -0.9876 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A18 compound treatment 422650.0 -42700.0 -0.43 407610.0 -60500.0 -0.63 -0.7556 -0.9829 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A19 compound treatment 365000.0 -100000.0 -1.02 440330.0 -27800.0 -0.29 -0.9274 -0.8742 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A20 compound treatment 414330.0 -51000.0 -0.52 421330.0 -46800.0 -0.49 -0.7137 -0.9996 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A21 compound treatment 428220.0 -37200.0 -0.38 456480.0 -11700.0 -0.12 -0.3535 -0.8906 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A22 compound treatment 340100.0 -125000.0 -1.27 451520.0 -16600.0 -0.17 -1.0235 -0.7965 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A23 compound treatment 345860.0 -120000.0 -1.21 347520.0 -121000.0 -1.26 -1.7526 -0.9998 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 A24 compound treatment 389070.0 -76300.0 -0.78 395680.0 -72500.0 -0.76 -1.0853 -0.9999 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B01 compound treatment 411280.0 -54100.0 -0.55 442590.0 -25600.0 -0.27 -0.5782 -0.9454 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B02 compound treatment 540320.0 74900.0 0.76 481690.0 13500.0 0.14 0.6388 0.8246 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B03 compound treatment 369960.0 -95400.0 -0.97 347320.0 -121000.0 -1.27 -1.5809 -0.9913 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B04 compound treatment 404160.0 -61200.0 -0.62 437200.0 -31000.0 -0.32 -0.6692 -0.9539 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B05 compound treatment 453650.0 -11700.0 -0.12 463970.0 -4190.0 -0.04 -0.1153 -0.9078 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B06 compound treatment 384870.0 -80500.0 -0.82 297830.0 -170000.0 -1.78 -1.8404 -0.9375 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B07 compound treatment 409230.0 -56100.0 -0.57 441300.0 -26900.0 -0.28 -0.6024 -0.9469 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B08 compound treatment 469390.0 4010.0 0.04 440070.0 -28100.0 -0.29 -0.1793 -0.6034 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B09 compound treatment 498880.0 33500.0 0.34 460390.0 -7770.0 -0.08 0.1832 0.5234 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B10 compound treatment 123880.0 -341000.0 -3.47 137670.0 -330000.0 -3.46 -4.9024 -1.0 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B11 compound treatment 390240.0 -75100.0 -0.76 368090.0 -100000.0 -1.05 -1.2813 -0.9879 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B12 compound treatment 240400.0 -225000.0 -2.29 272000.0 -196000.0 -2.06 -3.0699 -0.9986 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B13 mock treatment 512740.0 47400.0 0.48 426140.0 -42000.0 -0.44 0.029 0.0445 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B14 mock treatment 460770.0 -4610.0 -0.05 485500.0 17300.0 0.18 0.0954 0.5082 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B15 compound treatment 399630.0 -65700.0 -0.67 427520.0 -40600.0 -0.43 -0.7735 -0.9763 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B16 compound treatment 146250.0 -319000.0 -3.24 144080.0 -324000.0 -3.4 -4.6942 -0.9997 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B17 compound treatment 445920.0 -19500.0 -0.2 471710.0 3550.0 0.04 -0.1135 -0.564 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B18 compound treatment 149660.0 -316000.0 -3.21 155120.0 -313000.0 -3.28 -4.5879 -0.9999 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B19 compound treatment 457560.0 -7820.0 -0.08 445170.0 -23000.0 -0.24 -0.2265 -0.8931 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B20 compound treatment 189640.0 -276000.0 -2.8 172500.0 -296000.0 -3.1 -4.1718 -0.9987 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B21 compound treatment 445770.0 -19600.0 -0.2 489340.0 21200.0 0.22 0.016 0.0538 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B22 compound treatment 165120.0 -300000.0 -3.05 154680.0 -313000.0 -3.28 -4.48 -0.9993 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B23 compound treatment 335300.0 -130000.0 -1.32 486410.0 18300.0 0.19 -0.7995 -0.5986 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 B24 compound treatment 147360.0 -318000.0 -3.23 155580.0 -313000.0 -3.28 -4.601 -1.0 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C01 compound treatment 396640.0 -68700.0 -0.7 395260.0 -72900.0 -0.76 -1.034 -0.999 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C02 compound treatment 419840.0 -45500.0 -0.46 420050.0 -48100.0 -0.5 -0.6836 -0.9991 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C03 compound treatment 374940.0 -90400.0 -0.92 423920.0 -44200.0 -0.46 -0.9776 -0.9498 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C04 compound treatment 478990.0 13600.0 0.14 461450.0 -6710.0 -0.07 0.0481 0.3102 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C05 compound treatment 342910.0 -122000.0 -1.24 384480.0 -83700.0 -0.88 -1.5 -0.9853 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C06 compound treatment 423760.0 -41600.0 -0.42 448250.0 -19900.0 -0.21 -0.4465 -0.9469 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C07 compound treatment 383380.0 -82000.0 -0.83 472330.0 4170.0 0.04 -0.5583 -0.6691 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C08 compound treatment 418020.0 -47400.0 -0.48 518990.0 50800.0 0.53 0.0363 0.0506 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C09 compound treatment 442820.0 -22600.0 -0.23 426240.0 -41900.0 -0.44 -0.4726 -0.9541 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C10 compound treatment 360860.0 -105000.0 -1.06 411210.0 -56900.0 -0.6 -1.1729 -0.9628 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C11 mock treatment 437810.0 -27600.0 -0.28 408640.0 -59500.0 -0.62 -0.639 -0.9348 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C12 mock treatment 438560.0 -26800.0 -0.27 368640.0 -99500.0 -1.04 -0.93 -0.8629 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C13 compound treatment 57730.0 -408000.0 -4.14 27120.0 -441000.0 -4.62 -6.1968 -0.9985 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C14 compound treatment 357170.0 -108000.0 -1.1 441760.0 -26400.0 -0.28 -0.9731 -0.8582 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C15 mock treatment 419600.0 -45800.0 -0.47 487170.0 19000.0 0.2 -0.1881 -0.3717 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C16 mock treatment 416670.0 -48700.0 -0.49 457720.0 -10400.0 -0.11 -0.4273 -0.843 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C17 compound treatment 218080.0 -247000.0 -2.51 105380.0 -363000.0 -3.8 -4.4647 -0.9798 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C18 compound treatment 448690.0 -16700.0 -0.17 410190.0 -58000.0 -0.61 -0.5494 -0.8712 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C19 compound treatment 318660.0 -147000.0 -1.49 340480.0 -128000.0 -1.34 -2.0002 -0.9985 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C20 compound treatment 411850.0 -53500.0 -0.54 343810.0 -124000.0 -1.3 -1.3059 -0.925 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C21 compound treatment 379410.0 -86000.0 -0.87 441010.0 -27100.0 -0.28 -0.8189 -0.8913 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C22 compound treatment 406510.0 -58900.0 -0.6 442080.0 -26100.0 -0.27 -0.6162 -0.937 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C23 compound treatment 387080.0 -78300.0 -0.8 410920.0 -57200.0 -0.6 -0.9867 -0.9903 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 C24 compound treatment 411840.0 -53500.0 -0.54 415740.0 -52400.0 -0.55 -0.7731 -1.0 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D01 compound treatment 445080.0 -20300.0 -0.21 383130.0 -85000.0 -0.89 -0.7758 -0.8484 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D02 compound treatment 64640.0 -401000.0 -4.07 70970.0 -397000.0 -4.16 -5.8222 -0.9999 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D03 compound treatment 446640.0 -18700.0 -0.19 438640.0 -29500.0 -0.31 -0.3533 -0.9729 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D04 compound treatment 363120.0 -102000.0 -1.04 371280.0 -96900.0 -1.02 -1.4525 -0.9999 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D05 compound treatment 475740.0 10400.0 0.11 360090.0 -108000.0 -1.13 -0.7262 -0.6386 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D06 compound treatment 192960.0 -272000.0 -2.77 202460.0 -266000.0 -2.78 -3.926 -1.0 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D07 compound treatment 402150.0 -63200.0 -0.64 531450.0 63300.0 0.66 0.0146 0.0158 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D08 compound treatment 353660.0 -112000.0 -1.14 356320.0 -112000.0 -1.17 -1.6313 -0.9999 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D09 compound treatment 472320.0 6940.0 0.07 450940.0 -17200.0 -0.18 -0.0777 -0.401 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D10 compound treatment 263860.0 -202000.0 -2.05 264160.0 -204000.0 -2.14 -2.9594 -0.9998 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D11 mock treatment 463150.0 -2230.0 -0.02 405970.0 -62200.0 -0.65 -0.4767 -0.7312 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D12 mock treatment 476970.0 11600.0 0.12 467040.0 -1120.0 -0.01 0.075 0.6338 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D13 compound treatment 433940.0 -31400.0 -0.32 440560.0 -27600.0 -0.29 -0.4304 -0.9988 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D14 compound treatment 178680.0 -287000.0 -2.91 206840.0 -261000.0 -2.74 -3.9962 -0.9995 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D15 mock treatment 455920.0 -9460.0 -0.1 491540.0 23400.0 0.25 0.1053 0.4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D16 mock treatment 423680.0 -41700.0 -0.42 467910.0 -246.0 0.0 -0.3015 -0.7114 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D17 compound treatment 472160.0 6780.0 0.07 488800.0 20600.0 0.22 0.2017 0.8884 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D18 compound treatment 404640.0 -60700.0 -0.62 326310.0 -142000.0 -1.49 -1.4874 -0.9242 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D19 compound treatment 398520.0 -66900.0 -0.68 479490.0 11300.0 0.12 -0.3965 -0.5748 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D20 compound treatment 413700.0 -51700.0 -0.53 433150.0 -35000.0 -0.37 -0.6307 -0.9846 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D21 compound treatment 339000.0 -126000.0 -1.28 444420.0 -23700.0 -0.25 -1.084 -0.8286 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D22 compound treatment 410910.0 -54500.0 -0.55 378200.0 -90000.0 -0.94 -1.0579 -0.9678 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D23 compound treatment 356830.0 -109000.0 -1.1 374190.0 -94000.0 -0.98 -1.4762 -0.9984 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 D24 compound treatment 146620.0 -319000.0 -3.24 12190.0 -456000.0 -4.78 -5.6686 -0.9821 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E01 mock treatment 369220.0 -96200.0 -0.98 466770.0 -1390.0 -0.01 -0.7012 -0.7175 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E02 mock treatment 473680.0 8300.0 0.08 384450.0 -83700.0 -0.88 -0.5605 -0.6362 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E03 compound treatment 468030.0 2650.0 0.03 501010.0 32900.0 0.34 0.2625 0.7601 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E04 compound treatment 537460.0 72100.0 0.73 502660.0 34500.0 0.36 0.7736 0.947 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E05 compound treatment 422250.0 -43100.0 -0.44 530960.0 62800.0 0.66 0.1554 0.1965 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E06 compound treatment 412920.0 -52500.0 -0.53 486560.0 18400.0 0.19 -0.2406 -0.4244 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E07 compound treatment 499010.0 33600.0 0.34 446950.0 -21200.0 -0.22 0.0846 0.2074 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E08 compound treatment 499040.0 33700.0 0.34 446790.0 -21400.0 -0.22 0.0836 0.2045 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E09 mock treatment 402300.0 -63100.0 -0.64 488640.0 20500.0 0.21 -0.3015 -0.446 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E10 mock treatment 470970.0 5590.0 0.06 491200.0 23000.0 0.24 0.2109 0.8503 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E11 compound treatment 371370.0 -94000.0 -0.96 393600.0 -74600.0 -0.78 -1.2279 -0.995 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E12 compound treatment 350620.0 -115000.0 -1.17 285130.0 -183000.0 -1.92 -2.1806 -0.9716 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E13 compound treatment 450400.0 -15000.0 -0.15 489210.0 21100.0 0.22 0.0483 0.1804 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E14 compound treatment 251390.0 -214000.0 -2.17 295840.0 -172000.0 -1.81 -2.8143 -0.9957 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E15 compound treatment 459520.0 -5860.0 -0.06 460440.0 -7720.0 -0.08 -0.0993 -0.9887 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E16 compound treatment 259170.0 -206000.0 -2.1 262720.0 -205000.0 -2.15 -3.0038 -0.9999 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E17 mock treatment 408870.0 -56500.0 -0.57 468220.0 64.1 0.0 -0.4056 -0.7063 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E18 mock treatment 457820.0 -7560.0 -0.08 412650.0 -55500.0 -0.58 -0.4655 -0.7936 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E19 compound treatment 358560.0 -107000.0 -1.09 406510.0 -61600.0 -0.65 -1.2243 -0.9692 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E20 compound treatment 454140.0 -11200.0 -0.11 467530.0 -626.0 -0.01 -0.0854 -0.7465 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E21 compound treatment 375900.0 -89500.0 -0.91 460670.0 -7490.0 -0.08 -0.6984 -0.7653 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E22 compound treatment 462620.0 -2760.0 -0.03 468610.0 454.0 0.0 -0.0165 -0.5788 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E23 compound treatment 386960.0 -78400.0 -0.8 449620.0 -18500.0 -0.19 -0.7008 -0.8544 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 E24 compound treatment 435650.0 -29700.0 -0.3 493920.0 25800.0 0.27 -0.0227 -0.0561 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F01 mock treatment 458290.0 -7090.0 -0.07 521160.0 53000.0 0.56 0.3418 0.6103 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F02 mock treatment 438630.0 -26700.0 -0.27 473020.0 4860.0 0.05 -0.1562 -0.5647 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F03 compound treatment 457720.0 -7660.0 -0.08 482090.0 13900.0 0.15 0.0482 0.2913 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F04 compound treatment 381650.0 -83700.0 -0.85 401120.0 -67000.0 -0.7 -1.0983 -0.9955 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F05 compound treatment 337330.0 -128000.0 -1.3 488640.0 20500.0 0.21 -0.7684 -0.5826 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F06 compound treatment 407580.0 -57800.0 -0.59 455310.0 -12800.0 -0.13 -0.5105 -0.8472 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F07 compound treatment 325650.0 -140000.0 -1.42 337600.0 -131000.0 -1.37 -1.9713 -0.9998 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F08 compound treatment 470210.0 4830.0 0.05 420640.0 -47500.0 -0.5 -0.3173 -0.6343 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F09 mock treatment 401470.0 -63900.0 -0.65 507950.0 39800.0 0.42 -0.1644 -0.213 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F10 mock treatment 480860.0 15500.0 0.16 387960.0 -80200.0 -0.84 -0.4829 -0.5649 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F11 compound treatment 500370.0 35000.0 0.36 552960.0 84800.0 0.89 0.8797 0.9192 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F12 compound treatment 391910.0 -73500.0 -0.75 367290.0 -101000.0 -1.06 -1.2752 -0.9855 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F13 compound treatment 507560.0 42200.0 0.43 485230.0 17100.0 0.18 0.4296 0.9249 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F14 compound treatment 454770.0 -10600.0 -0.11 507680.0 39500.0 0.41 0.2166 0.5061 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F15 compound treatment 445860.0 -19500.0 -0.2 434640.0 -33500.0 -0.35 -0.3886 -0.9634 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F16 compound treatment 192960.0 -272000.0 -2.77 214820.0 -253000.0 -2.65 -3.8344 -0.9998 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F17 mock treatment 488580.0 23200.0 0.24 465610.0 -2550.0 -0.03 0.1479 0.6231 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F18 mock treatment 436190.0 -29200.0 -0.3 419470.0 -48700.0 -0.51 -0.5704 -0.9667 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F19 compound treatment 453800.0 -11600.0 -0.12 390910.0 -77200.0 -0.81 -0.6555 -0.8015 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F20 compound treatment 424450.0 -40900.0 -0.42 461790.0 -6370.0 -0.07 -0.3413 -0.8101 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F21 compound treatment 489700.0 24300.0 0.25 499690.0 31500.0 0.33 0.4084 0.9898 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F22 compound treatment 474570.0 9190.0 0.09 401700.0 -66500.0 -0.7 -0.4263 -0.6068 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F23 compound treatment 457610.0 -7770.0 -0.08 440670.0 -27500.0 -0.29 -0.2595 -0.8689 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 F24 compound treatment 471530.0 6150.0 0.06 431480.0 -36700.0 -0.38 -0.2275 -0.5844 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G01 compound treatment 534510.0 69100.0 0.7 480440.0 12300.0 0.13 0.5878 0.823 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G02 compound treatment 514190.0 48800.0 0.5 463280.0 -4880.0 -0.05 0.3146 0.6309 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G03 mock treatment 452280.0 -13100.0 -0.13 509810.0 41700.0 0.44 0.2145 0.4701 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G04 mock treatment 537240.0 71900.0 0.73 453720.0 -14400.0 -0.15 0.4094 0.549 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G05 compound treatment 523460.0 58100.0 0.59 492000.0 23800.0 0.25 0.594 0.9268 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G06 compound treatment 496230.0 30900.0 0.31 500240.0 32100.0 0.34 0.4594 0.9994 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G07 compound treatment 509550.0 44200.0 0.45 565400.0 97200.0 1.02 1.0379 0.9322 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G08 compound treatment 451360.0 -14000.0 -0.14 588390.0 120000.0 1.26 0.79 0.6232 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G09 compound treatment 502240.0 36900.0 0.37 582600.0 114000.0 1.2 1.1128 0.8858 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G10 compound treatment 449170.0 -16200.0 -0.16 443380.0 -24800.0 -0.26 -0.3 -0.9759 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G11 compound treatment 444160.0 -21200.0 -0.22 415420.0 -52700.0 -0.55 -0.5432 -0.9158 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G12 compound treatment 334290.0 -131000.0 -1.33 230890.0 -237000.0 -2.49 -2.6998 -0.9572 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G13 compound treatment 403680.0 -61700.0 -0.63 452160.0 -16000.0 -0.17 -0.5619 -0.8657 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G14 compound treatment 443880.0 -21500.0 -0.22 410210.0 -57900.0 -0.61 -0.5838 -0.9048 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G15 compound treatment 515140.0 49800.0 0.51 480810.0 12700.0 0.13 0.4513 0.8633 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G16 compound treatment 442850.0 -22500.0 -0.23 488070.0 19900.0 0.21 -0.0143 -0.0463 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G17 compound treatment 443360.0 -22000.0 -0.22 491520.0 23400.0 0.24 0.0149 0.0449 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G18 compound treatment 484110.0 18700.0 0.19 466460.0 -1700.0 -0.02 0.122 0.6383 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G19 mock treatment 474620.0 9240.0 0.09 430850.0 -37300.0 -0.39 -0.21 -0.5224 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G20 mock treatment 446290.0 -19100.0 -0.19 454240.0 -13900.0 -0.15 -0.2403 -0.9901 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G21 compound treatment 505990.0 40600.0 0.41 479780.0 11600.0 0.12 0.3779 0.8783 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G22 compound treatment 459960.0 -5420.0 -0.06 428670.0 -39500.0 -0.41 -0.3315 -0.7942 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G23 compound treatment 452030.0 -13300.0 -0.14 421250.0 -46900.0 -0.49 -0.4434 -0.8698 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 G24 compound treatment 438460.0 -26900.0 -0.27 474250.0 6090.0 0.06 -0.1483 -0.5279 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H01 compound treatment 518650.0 53300.0 0.54 428500.0 -39700.0 -0.42 0.089 0.1304 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H02 compound treatment 259920.0 -205000.0 -2.09 308250.0 -160000.0 -1.68 -2.6611 -0.994 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H03 mock treatment 512760.0 47400.0 0.48 579960.0 112000.0 1.17 1.1688 0.9228 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H04 mock treatment 564590.0 99200.0 1.01 470170.0 2010.0 0.02 0.7278 0.7217 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H05 compound treatment 442290.0 -23100.0 -0.23 376540.0 -91600.0 -0.96 -0.8447 -0.8548 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H06 compound treatment 304840.0 -161000.0 -1.63 317440.0 -151000.0 -1.58 -2.2702 -0.9999 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H07 compound treatment 388750.0 -76600.0 -0.78 362270.0 -106000.0 -1.11 -1.3351 -0.985 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H08 mock treatment 549450.0 84100.0 0.85 537230.0 69100.0 0.72 1.1159 0.9966 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H09 compound treatment 457490.0 -7890.0 -0.08 386600.0 -81600.0 -0.85 -0.6609 -0.7701 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H10 mock treatment 543600.0 78200.0 0.79 493350.0 25200.0 0.26 0.7487 0.8939 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H11 compound treatment 486670.0 21300.0 0.22 363520.0 -105000.0 -1.1 -0.6222 -0.5568 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H12 mock treatment 566770.0 101000.0 1.03 565520.0 97400.0 1.02 1.4499 1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H13 compound treatment 455880.0 -9500.0 -0.1 429760.0 -38400.0 -0.4 -0.3527 -0.8526 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H14 mock treatment 461830.0 -3550.0 -0.04 396190.0 -72000.0 -0.75 -0.5587 -0.7401 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H15 compound treatment 392580.0 -72800.0 -0.74 544080.0 75900.0 0.8 0.0394 0.0363 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H16 mock treatment 479680.0 14300.0 0.15 483210.0 15100.0 0.16 0.2143 0.9992 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H17 compound treatment 514280.0 48900.0 0.5 511860.0 43700.0 0.46 0.6752 0.9992 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H18 mock treatment 543440.0 78100.0 0.79 493470.0 25300.0 0.27 0.7485 0.8948 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H19 mock treatment 471910.0 6530.0 0.07 546460.0 78300.0 0.82 0.6271 0.7618 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H20 mock treatment 488440.0 23100.0 0.23 427390.0 -40800.0 -0.43 -0.1363 -0.2798 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H21 compound treatment 483080.0 17700.0 0.18 419870.0 -48300.0 -0.51 -0.2305 -0.4294 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H22 mock treatment 433280.0 -32100.0 -0.33 431100.0 -37100.0 -0.39 -0.5052 -0.9962 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H23 compound treatment 382930.0 -82400.0 -0.84 401940.0 -66200.0 -0.69 -1.083 -0.9956 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 H24 mock treatment 479000.0 13600.0 0.14 446680.0 -21500.0 -0.23 -0.0612 -0.2318 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I01 compound treatment 489070.0 23700.0 0.24 403780.0 -64400.0 -0.67 -0.3067 -0.4283 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I02 compound treatment 478320.0 12900.0 0.13 423970.0 -44200.0 -0.46 -0.2344 -0.487 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I03 compound treatment 114980.0 -350000.0 -3.56 138930.0 -329000.0 -3.45 -4.957 -0.9999 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I04 compound treatment 282840.0 -183000.0 -1.85 319900.0 -148000.0 -1.55 -2.4101 -0.9961 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I05 mock treatment 421180.0 -44200.0 -0.45 541600.0 73400.0 0.77 0.2265 0.2542 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I06 mock treatment 399060.0 -66300.0 -0.67 382670.0 -85500.0 -0.9 -1.1099 -0.9902 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I07 compound treatment 445760.0 -19600.0 -0.2 422850.0 -45300.0 -0.47 -0.4766 -0.9258 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I08 compound treatment 268710.0 -197000.0 -2.0 261600.0 -207000.0 -2.16 -2.9435 -0.9992 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I09 compound treatment 403300.0 -62100.0 -0.63 464500.0 -3660.0 -0.04 -0.4732 -0.7487 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I10 compound treatment 231310.0 -234000.0 -2.38 250730.0 -217000.0 -2.28 -3.2928 -0.9998 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I11 compound treatment 500640.0 35300.0 0.36 442470.0 -25700.0 -0.27 0.0631 0.1407 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I12 compound treatment 270470.0 -195000.0 -1.98 287760.0 -180000.0 -1.89 -2.7371 -0.9997 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I13 compound treatment 537000.0 71600.0 0.73 482240.0 14100.0 0.15 0.619 0.8335 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I14 compound treatment 268340.0 -197000.0 -2.0 218720.0 -249000.0 -2.61 -3.2639 -0.9913 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I15 compound treatment 440320.0 -25100.0 -0.25 507840.0 39700.0 0.42 0.1139 0.2337 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I16 compound treatment 177070.0 -288000.0 -2.93 171160.0 -297000.0 -3.11 -4.2721 -0.9995 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I17 compound treatment 462020.0 -3360.0 -0.03 433510.0 -34600.0 -0.36 -0.2808 -0.7702 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I18 compound treatment 315560.0 -150000.0 -1.52 324530.0 -144000.0 -1.5 -2.1406 -1.0 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I19 compound treatment 492100.0 26700.0 0.27 397730.0 -70400.0 -0.74 -0.3298 -0.4194 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I20 compound treatment 310420.0 -155000.0 -1.57 364990.0 -103000.0 -1.08 -1.8778 -0.9831 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I21 mock treatment 411630.0 -53700.0 -0.55 544770.0 76600.0 0.8 0.1814 0.1868 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I22 mock treatment 455700.0 -9680.0 -0.1 503590.0 35400.0 0.37 0.193 0.5024 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I23 compound treatment 321120.0 -144000.0 -1.47 406950.0 -61200.0 -0.64 -1.4901 -0.9312 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 I24 compound treatment 224320.0 -241000.0 -2.45 171840.0 -296000.0 -3.1 -3.9275 -0.9931 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J01 compound treatment 488240.0 22900.0 0.23 508110.0 40000.0 0.42 0.4603 0.9614 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J02 mock treatment 443250.0 -22100.0 -0.22 474600.0 6440.0 0.07 -0.1113 -0.4739 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J03 compound treatment 237010.0 -228000.0 -2.32 296440.0 -172000.0 -1.8 -2.9132 -0.9921 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J04 mock treatment 342830.0 -123000.0 -1.25 479570.0 11400.0 0.12 -0.796 -0.6363 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J05 mock treatment 354090.0 -111000.0 -1.13 456210.0 -11900.0 -0.13 -0.8882 -0.7806 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J06 mock treatment 435200.0 -30200.0 -0.31 394400.0 -73800.0 -0.77 -0.7633 -0.9181 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J07 compound treatment 407610.0 -57800.0 -0.59 466740.0 -1420.0 -0.01 -0.4256 -0.7247 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J08 mock treatment 426080.0 -39300.0 -0.4 500240.0 32100.0 0.34 -0.0447 -0.0856 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J09 compound treatment 434590.0 -30800.0 -0.31 483540.0 15400.0 0.16 -0.1073 -0.3048 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J10 mock treatment 472490.0 7110.0 0.07 513120.0 45000.0 0.47 0.3842 0.8061 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J11 compound treatment 411460.0 -53900.0 -0.55 459520.0 -8640.0 -0.09 -0.4514 -0.8129 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J12 mock treatment 518400.0 53000.0 0.54 517280.0 49100.0 0.51 0.7449 0.9997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J13 compound treatment 439840.0 -25500.0 -0.26 473490.0 5330.0 0.06 -0.144 -0.5424 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J14 mock treatment 472330.0 6950.0 0.07 519910.0 51800.0 0.54 0.4334 0.7925 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J15 compound treatment 462080.0 -3300.0 -0.03 483240.0 15100.0 0.16 0.088 0.545 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J16 mock treatment 468230.0 2850.0 0.03 448800.0 -19400.0 -0.2 -0.1229 -0.6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J17 compound treatment 484690.0 19300.0 0.2 489050.0 20900.0 0.22 0.2936 0.9985 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J18 mock treatment 454520.0 -10900.0 -0.11 478330.0 10200.0 0.11 -0.0027 -0.0173 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J19 compound treatment 466370.0 991.0 0.01 460510.0 -7650.0 -0.08 -0.0495 -0.6134 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J20 mock treatment 447200.0 -18200.0 -0.18 485460.0 17300.0 0.18 -0.0024 -0.0094 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J21 mock treatment 470720.0 5340.0 0.05 470960.0 2800.0 0.03 0.0592 0.9585 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J22 mock treatment 425190.0 -40200.0 -0.41 388280.0 -79900.0 -0.84 -0.8806 -0.9456 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J23 compound treatment 355610.0 -110000.0 -1.12 402990.0 -65200.0 -0.68 -1.2716 -0.9722 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 J24 mock treatment 427840.0 -37500.0 -0.38 360750.0 -107000.0 -1.13 -1.0655 -0.8967 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K01 compound treatment 9470.0 -456000.0 -4.63 8160.0 -460000.0 -4.82 -6.684 -0.9998 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K02 compound treatment 111570.0 -354000.0 -3.6 127970.0 -340000.0 -3.56 -5.0627 -1.0 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K03 compound treatment 10680.0 -455000.0 -4.62 10880.0 -457000.0 -4.79 -6.6552 -0.9998 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K04 compound treatment 293800.0 -172000.0 -1.74 343570.0 -125000.0 -1.31 -2.1559 -0.9898 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K05 compound treatment 140210.0 -325000.0 -3.3 218260.0 -250000.0 -2.62 -4.188 -0.9934 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K06 compound treatment 162520.0 -303000.0 -3.08 176160.0 -292000.0 -3.06 -4.3396 -1.0 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K07 mock treatment 549120.0 83700.0 0.85 560960.0 92800.0 0.97 1.2893 0.9978 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K08 mock treatment 550720.0 85300.0 0.87 500610.0 32500.0 0.34 0.8537 0.9164 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K09 compound treatment 388270.0 -77100.0 -0.78 377050.0 -91100.0 -0.95 -1.2291 -0.9952 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K10 compound treatment 340840.0 -125000.0 -1.27 414600.0 -53600.0 -0.56 -1.2917 -0.933 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K11 compound treatment 356360.0 -109000.0 -1.11 345160.0 -123000.0 -1.29 -1.6946 -0.9972 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K12 compound treatment 436420.0 -29000.0 -0.29 429760.0 -38400.0 -0.4 -0.4926 -0.9882 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K13 compound treatment 467650.0 2270.0 0.02 458680.0 -9480.0 -0.1 -0.0539 -0.5287 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K14 compound treatment 478560.0 13200.0 0.13 542940.0 74800.0 0.78 0.6488 0.8161 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K15 mock treatment 463260.0 -2120.0 -0.02 440810.0 -27300.0 -0.29 -0.2178 -0.7581 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K16 mock treatment 539370.0 74000.0 0.75 476070.0 7910.0 0.08 0.5903 0.7804 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K17 compound treatment 453300.0 -12100.0 -0.12 466680.0 -1480.0 -0.02 -0.0977 -0.7899 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K18 compound treatment 486890.0 21500.0 0.22 456110.0 -12000.0 -0.13 0.0653 0.2588 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K19 compound treatment 473440.0 8060.0 0.08 538610.0 70500.0 0.74 0.5799 0.7808 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K20 compound treatment 412410.0 -53000.0 -0.54 458730.0 -9430.0 -0.1 -0.4505 -0.8231 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K21 compound treatment 456050.0 -9330.0 -0.09 472360.0 4200.0 0.04 -0.0359 -0.3433 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K22 compound treatment 451680.0 -13700.0 -0.14 439360.0 -28800.0 -0.3 -0.3118 -0.9383 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K23 mock treatment 474560.0 9180.0 0.09 490640.0 22500.0 0.24 0.2325 0.9178 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 K24 mock treatment 482920.0 17500.0 0.18 399210.0 -68900.0 -0.72 -0.3848 -0.5171 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L01 compound treatment 484720.0 19300.0 0.2 473630.0 5470.0 0.06 0.1795 0.8769 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L02 mock treatment 534240.0 68900.0 0.7 542400.0 74200.0 0.78 1.0449 0.9986 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L03 compound treatment 507850.0 42500.0 0.43 337450.0 -131000.0 -1.37 -0.6632 -0.4619 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L04 mock treatment 444320.0 -21100.0 -0.21 457520.0 -10600.0 -0.11 -0.2301 -0.9538 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L05 compound treatment 470850.0 5470.0 0.06 436990.0 -31200.0 -0.33 -0.1916 -0.5784 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L06 mock treatment 338330.0 -127000.0 -1.29 344250.0 -124000.0 -1.3 -1.8309 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L07 mock treatment 532270.0 66900.0 0.68 480840.0 12700.0 0.13 0.5746 0.8296 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L08 mock treatment 471960.0 6580.0 0.07 502600.0 34400.0 0.36 0.3025 0.8241 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L09 compound treatment 527930.0 62600.0 0.64 460220.0 -7940.0 -0.08 0.3907 0.6094 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L10 mock treatment 507970.0 42600.0 0.43 540580.0 72400.0 0.76 0.8426 0.9646 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L11 compound treatment 459920.0 -5460.0 -0.06 517280.0 49100.0 0.51 0.3247 0.6273 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L12 mock treatment 534130.0 68800.0 0.7 485640.0 17500.0 0.18 0.6236 0.8633 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L13 compound treatment 431410.0 -34000.0 -0.35 500720.0 32600.0 0.34 -0.0028 -0.0058 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L14 mock treatment 504340.0 39000.0 0.4 458470.0 -9690.0 -0.1 0.2082 0.5094 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L15 mock treatment 575050.0 110000.0 1.11 508340.0 40200.0 0.42 1.0858 0.9114 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L16 mock treatment 498030.0 32700.0 0.33 529780.0 61600.0 0.65 0.6912 0.9521 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L17 compound treatment 521480.0 56100.0 0.57 552010.0 83900.0 0.88 1.0244 0.9781 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L18 mock treatment 530080.0 64700.0 0.66 506320.0 38200.0 0.4 0.7477 0.9716 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L19 compound treatment 490300.0 24900.0 0.25 515840.0 47700.0 0.5 0.5324 0.9504 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L20 mock treatment 528190.0 62800.0 0.64 470820.0 2660.0 0.03 0.4711 0.7373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L21 compound treatment 502560.0 37200.0 0.38 534400.0 66200.0 0.69 0.758 0.9591 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L22 mock treatment 527050.0 61700.0 0.63 476160.0 8000.0 0.08 0.5024 0.7946 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L23 mock treatment 518210.0 52800.0 0.54 470120.0 1960.0 0.02 0.3942 0.7337 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 L24 mock treatment 455700.0 -9680.0 -0.1 495840.0 27700.0 0.29 0.1356 0.4426 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M01 compound treatment 11380.0 -454000.0 -4.61 12410.0 -456000.0 -4.78 -6.6388 -0.9999 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M02 compound treatment 372740.0 -92600.0 -0.94 413440.0 -54700.0 -0.57 -1.0711 -0.9717 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M03 compound treatment 360530.0 -105000.0 -1.07 325880.0 -142000.0 -1.49 -1.8075 -0.9864 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M04 compound treatment 423420.0 -42000.0 -0.43 461540.0 -6620.0 -0.07 -0.3505 -0.8114 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M05 compound treatment 18690.0 -447000.0 -4.54 14320.0 -454000.0 -4.76 -6.5721 -0.9997 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M06 compound treatment 450000.0 -15400.0 -0.16 406130.0 -62000.0 -0.65 -0.57 -0.8528 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M07 compound treatment 433790.0 -31600.0 -0.32 483040.0 14900.0 0.16 -0.1167 -0.327 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M08 compound treatment 315270.0 -150000.0 -1.53 425290.0 -42900.0 -0.45 -1.3962 -0.878 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M09 mock treatment 456680.0 -8700.0 -0.09 518250.0 50100.0 0.52 0.3086 0.5798 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M10 mock treatment 463790.0 -1590.0 -0.02 563100.0 94900.0 0.99 0.692 0.6955 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M11 compound treatment 442910.0 -22500.0 -0.23 405980.0 -62200.0 -0.65 -0.6221 -0.9012 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M12 compound treatment 468510.0 3130.0 0.03 512130.0 44000.0 0.46 0.3483 0.7541 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M13 mock treatment 492990.0 27600.0 0.28 549960.0 81800.0 0.86 0.8045 0.892 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M14 mock treatment 501380.0 36000.0 0.37 471160.0 3000.0 0.03 0.2809 0.7651 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M15 compound treatment 457620.0 -7760.0 -0.08 443200.0 -25000.0 -0.26 -0.2406 -0.8811 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M16 compound treatment 537050.0 71700.0 0.73 470880.0 2720.0 0.03 0.5352 0.7343 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M17 compound treatment 482340.0 17000.0 0.17 522610.0 54500.0 0.57 0.5253 0.8814 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M18 compound treatment 477510.0 12100.0 0.12 449760.0 -18400.0 -0.19 -0.0491 -0.2147 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M19 compound treatment 399750.0 -65600.0 -0.67 493380.0 25200.0 0.26 -0.2847 -0.3969 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M20 compound treatment 432990.0 -32400.0 -0.33 429470.0 -38700.0 -0.41 -0.5194 -0.9947 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M21 compound treatment 466610.0 1230.0 0.01 402290.0 -65900.0 -0.69 -0.4791 -0.6942 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M22 compound treatment 369290.0 -96100.0 -0.98 407060.0 -61100.0 -0.64 -1.1431 -0.979 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M23 compound treatment 472920.0 7540.0 0.08 425920.0 -42200.0 -0.44 -0.2587 -0.5761 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 M24 compound treatment 311420.0 -154000.0 -1.56 311000.0 -157000.0 -1.65 -2.2706 -0.9997 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N01 compound treatment 458420.0 -6960.0 -0.07 425510.0 -42600.0 -0.45 -0.366 -0.809 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N02 mock treatment 433470.0 -31900.0 -0.32 471900.0 3740.0 0.04 -0.2016 -0.6171 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N03 compound treatment 496160.0 30800.0 0.31 474520.0 6360.0 0.07 0.2683 0.839 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N04 mock treatment 459370.0 -6010.0 -0.06 457540.0 -10600.0 -0.11 -0.1218 -0.9601 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N05 compound treatment 482830.0 17500.0 0.18 368240.0 -99900.0 -1.05 -0.6149 -0.5791 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N06 mock treatment 419860.0 -45500.0 -0.46 391680.0 -76500.0 -0.8 -0.8937 -0.9659 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N07 compound treatment 472920.0 7540.0 0.08 472660.0 4500.0 0.05 0.0876 0.9729 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N08 mock treatment 517440.0 52100.0 0.53 383250.0 -84900.0 -0.89 -0.255 -0.2463 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N09 mock treatment 457200.0 -8180.0 -0.08 476970.0 8810.0 0.09 0.0065 0.0525 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N10 mock treatment 414680.0 -50700.0 -0.52 524980.0 56800.0 0.6 0.0567 0.072 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N11 compound treatment 480960.0 15600.0 0.16 478590.0 10400.0 0.11 0.1893 0.9836 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N12 mock treatment 446280.0 -19100.0 -0.19 487680.0 19500.0 0.2 0.0074 0.0263 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N13 mock treatment 574150.0 109000.0 1.11 410200.0 -58000.0 -0.61 0.3522 0.2793 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N14 mock treatment 481170.0 15800.0 0.16 533230.0 65100.0 0.68 0.5956 0.8503 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N15 compound treatment 496930.0 31600.0 0.32 532530.0 64400.0 0.67 0.7036 0.9422 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N16 mock treatment 535050.0 69700.0 0.71 520330.0 52200.0 0.55 0.8872 0.9918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N17 compound treatment 467250.0 1870.0 0.02 480030.0 11900.0 0.12 0.1014 0.8058 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N18 mock treatment 421180.0 -44200.0 -0.45 474510.0 6350.0 0.07 -0.2705 -0.5958 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N19 compound treatment 349130.0 -116000.0 -1.18 350500.0 -118000.0 -1.23 -1.707 -0.9998 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N20 mock treatment 488160.0 22800.0 0.23 448000.0 -20200.0 -0.21 0.0144 0.0458 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N21 compound treatment 409700.0 -55700.0 -0.57 381450.0 -86700.0 -0.91 -1.0425 -0.974 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N22 mock treatment 480550.0 15200.0 0.15 420920.0 -47200.0 -0.49 -0.2409 -0.4648 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N23 compound treatment 386080.0 -79300.0 -0.81 389190.0 -79000.0 -0.83 -1.1549 -0.9999 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 N24 mock treatment 425140.0 -40200.0 -0.41 498640.0 30500.0 0.32 -0.0633 -0.122 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O01 compound treatment 127270.0 -338000.0 -3.44 143360.0 -325000.0 -3.4 -4.8359 -1.0 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O02 compound treatment 504080.0 38700.0 0.39 497370.0 29200.0 0.31 0.4945 0.9923 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O03 compound treatment 456800.0 -8580.0 -0.09 433870.0 -34300.0 -0.36 -0.3157 -0.8539 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O04 compound treatment 363360.0 -102000.0 -1.04 468660.0 504.0 0.01 -0.7293 -0.7035 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O05 compound treatment 438050.0 -27300.0 -0.28 440880.0 -27300.0 -0.29 -0.3985 -0.9999 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O06 compound treatment 399050.0 -66300.0 -0.67 391000.0 -77200.0 -0.81 -1.0482 -0.9959 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O07 compound treatment 432990.0 -32400.0 -0.33 418650.0 -49500.0 -0.52 -0.5995 -0.9759 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O08 compound treatment 392090.0 -73300.0 -0.74 491960.0 23800.0 0.25 -0.3503 -0.446 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O09 compound treatment 464430.0 -949.0 -0.01 553410.0 85300.0 0.89 0.6248 0.6994 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O10 compound treatment 382190.0 -83200.0 -0.85 418150.0 -50000.0 -0.52 -0.9683 -0.9735 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O11 mock treatment 536990.0 71600.0 0.73 530400.0 62200.0 0.65 0.9757 0.9985 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O12 mock treatment 465760.0 381.0 0.0 566400.0 98200.0 1.03 0.7306 0.7098 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O13 compound treatment 498250.0 32900.0 0.33 495540.0 27400.0 0.29 0.4391 0.9971 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O14 compound treatment 468530.0 3150.0 0.03 439770.0 -28400.0 -0.3 -0.1877 -0.6274 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O15 compound treatment 435010.0 -30400.0 -0.31 505440.0 37300.0 0.39 0.058 0.1165 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O16 compound treatment 464400.0 -979.0 -0.01 515420.0 47300.0 0.5 0.3431 0.6928 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O17 compound treatment 463950.0 -1430.0 -0.01 466750.0 -1410.0 -0.01 -0.0207 -1.0 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O18 compound treatment 452130.0 -13200.0 -0.13 483050.0 14900.0 0.16 0.0151 0.0735 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O19 compound treatment 482560.0 17200.0 0.17 468320.0 164.0 0.0 0.1247 0.714 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O20 compound treatment 430490.0 -34900.0 -0.35 398020.0 -70100.0 -0.73 -0.7703 -0.9441 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O21 compound treatment 528760.0 63400.0 0.64 412370.0 -55800.0 -0.58 0.0421 0.0484 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O22 compound treatment 437830.0 -27500.0 -0.28 456600.0 -11600.0 -0.12 -0.2836 -0.9297 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O23 compound treatment 397200.0 -68200.0 -0.69 472100.0 3940.0 0.04 -0.4607 -0.6638 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 O24 compound treatment 397680.0 -67700.0 -0.69 441060.0 -27100.0 -0.28 -0.6872 -0.9234 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P01 compound treatment 231090.0 -234000.0 -2.38 282560.0 -186000.0 -1.94 -3.0586 -0.995 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P02 mock treatment 405060.0 -60300.0 -0.61 439410.0 -28700.0 -0.3 -0.6464 -0.9465 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P03 compound treatment 354100.0 -111000.0 -1.13 358570.0 -110000.0 -1.15 -1.6115 -1.0 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P04 mock treatment 422170.0 -43200.0 -0.44 451310.0 -16800.0 -0.18 -0.4353 -0.9198 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P05 compound treatment 384550.0 -80800.0 -0.82 456390.0 -11800.0 -0.12 -0.668 -0.8042 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P06 mock treatment 424440.0 -40900.0 -0.42 468520.0 364.0 0.0 -0.2915 -0.7006 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P07 compound treatment 393720.0 -71700.0 -0.73 388000.0 -80200.0 -0.84 -1.1088 -0.9975 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P08 mock treatment 447840.0 -17500.0 -0.18 407050.0 -61100.0 -0.64 -0.5787 -0.8708 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P09 compound treatment 294440.0 -171000.0 -1.74 351110.0 -117000.0 -1.23 -2.0955 -0.9855 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P10 mock treatment 405170.0 -60200.0 -0.61 428730.0 -39400.0 -0.41 -0.7247 -0.9817 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P11 mock treatment 428590.0 -36800.0 -0.37 498080.0 29900.0 0.31 -0.0427 -0.0874 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P12 mock treatment 449980.0 -15400.0 -0.16 395270.0 -72900.0 -0.76 -0.6506 -0.8347 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P13 compound treatment 267240.0 -198000.0 -2.01 263460.0 -205000.0 -2.14 -2.9403 -0.9995 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P14 mock treatment 422830.0 -42500.0 -0.43 427630.0 -40500.0 -0.42 -0.606 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P15 compound treatment 312960.0 -152000.0 -1.55 336600.0 -132000.0 -1.38 -2.0699 -0.9983 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P16 mock treatment 462800.0 -2580.0 -0.03 408640.0 -59500.0 -0.62 -0.4595 -0.7362 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P17 compound treatment 290420.0 -175000.0 -1.78 246100.0 -222000.0 -2.33 -2.9024 -0.9912 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P18 mock treatment 386290.0 -79100.0 -0.8 435890.0 -32300.0 -0.34 -0.8074 -0.926 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P19 compound treatment 389990.0 -75400.0 -0.77 378080.0 -90100.0 -0.94 -1.2091 -0.9946 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P20 mock treatment 427090.0 -38300.0 -0.39 413490.0 -54700.0 -0.57 -0.6801 -0.9823 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P21 compound treatment 402520.0 -62900.0 -0.64 409390.0 -58800.0 -0.62 -0.8871 -0.9998 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P22 mock treatment 484090.0 18700.0 0.19 433670.0 -34500.0 -0.36 -0.121 -0.2965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P23 compound treatment 350730.0 -115000.0 -1.17 327060.0 -141000.0 -1.48 -1.8692 -0.9931 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2283 P24 mock treatment 352280.0 -113000.0 -1.15 401950.0 -66200.0 -0.69 -1.3032 -0.9708 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A01 mock treatment 354410.0 -100000.0 -1.02 375200.0 -70600.0 -0.74 -1.2424 -0.9877 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A02 compound treatment 419150.0 -35400.0 -0.36 334730.0 -111000.0 -1.16 -1.077 -0.8844 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A03 mock treatment 375400.0 -79100.0 -0.8 341500.0 -104000.0 -1.09 -1.3413 -0.9886 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A04 compound treatment 417760.0 -36800.0 -0.37 392030.0 -53800.0 -0.56 -0.6625 -0.9801 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A05 compound treatment 352110.0 -102000.0 -1.04 399800.0 -46000.0 -0.48 -1.0767 -0.9387 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A06 compound treatment 272880.0 -182000.0 -1.85 270110.0 -176000.0 -1.84 -2.6068 -1.0 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A07 mock treatment 427100.0 -27400.0 -0.28 464440.0 18700.0 0.2 -0.0589 -0.1731 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A08 compound treatment 395840.0 -58700.0 -0.6 474530.0 28700.0 0.3 -0.2088 -0.3125 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A09 compound treatment 446910.0 -7620.0 -0.08 416590.0 -29200.0 -0.31 -0.2711 -0.8591 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A10 compound treatment 350780.0 -104000.0 -1.05 386880.0 -58900.0 -0.62 -1.182 -0.9675 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A11 mock treatment 462790.0 8260.0 0.08 414470.0 -31300.0 -0.33 -0.1727 -0.5099 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A12 compound treatment 430970.0 -23600.0 -0.24 421700.0 -24100.0 -0.25 -0.3478 -0.9997 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A13 mock treatment 421510.0 -33000.0 -0.34 387740.0 -58000.0 -0.61 -0.6673 -0.9607 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A14 mock treatment 444360.0 -10200.0 -0.1 438620.0 -7170.0 -0.08 -0.1262 -0.9876 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A15 compound treatment 427110.0 -27400.0 -0.28 360660.0 -85100.0 -0.89 -0.8277 -0.8858 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A16 compound treatment 460230.0 5700.0 0.06 472390.0 26600.0 0.28 0.238 0.8361 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A17 compound treatment 257710.0 -197000.0 -2.0 249550.0 -196000.0 -2.06 -2.8682 -0.9999 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A18 compound treatment 31040.0 -423000.0 -4.3 32330.0 -413000.0 -4.33 -6.1063 -1.0 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A19 compound treatment 379550.0 -75000.0 -0.76 375640.0 -70100.0 -0.73 -1.0585 -0.9998 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A20 compound treatment 382170.0 -72400.0 -0.74 424680.0 -21100.0 -0.22 -0.6764 -0.8808 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A21 compound treatment 450160.0 -4370.0 -0.04 447110.0 1320.0 0.01 -0.0216 -0.4643 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A22 compound treatment 453770.0 -764.0 -0.01 483620.0 37800.0 0.4 0.2748 0.6931 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A23 compound treatment 425870.0 -28700.0 -0.29 438690.0 -7100.0 -0.07 -0.2585 -0.86 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 A24 compound treatment 336450.0 -118000.0 -1.2 393060.0 -52700.0 -0.55 -1.2391 -0.938 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B01 compound treatment 460160.0 5630.0 0.06 542610.0 96800.0 1.01 0.7578 0.7458 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B02 compound treatment 262620.0 -192000.0 -1.95 225280.0 -221000.0 -2.31 -3.0127 -0.9964 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B03 compound treatment 452710.0 -1820.0 -0.02 452930.0 7140.0 0.07 0.0398 0.5164 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B04 compound treatment 531610.0 77100.0 0.78 450950.0 5160.0 0.05 0.5921 0.7542 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B05 compound treatment 394430.0 -60100.0 -0.61 420040.0 -25700.0 -0.27 -0.6226 -0.9325 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B06 compound treatment 340430.0 -114000.0 -1.16 456910.0 11100.0 0.12 -0.7375 -0.6328 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B07 compound treatment 421540.0 -33000.0 -0.34 486050.0 40300.0 0.42 0.0612 0.1136 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B08 compound treatment 482760.0 28200.0 0.29 408670.0 -37100.0 -0.39 -0.0722 -0.1493 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B09 compound treatment 404990.0 -49500.0 -0.5 383360.0 -62400.0 -0.65 -0.8185 -0.9916 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B10 compound treatment 503810.0 49300.0 0.5 404530.0 -41300.0 -0.43 0.0484 0.0732 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B11 compound treatment 496540.0 42000.0 0.43 500060.0 54300.0 0.57 0.7039 0.99 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B12 compound treatment 450590.0 -3940.0 -0.04 448640.0 2850.0 0.03 -0.0072 -0.1439 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B13 mock treatment 468330.0 13800.0 0.14 504330.0 58500.0 0.61 0.5329 0.8469 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B14 mock treatment 443130.0 -11400.0 -0.12 425300.0 -20500.0 -0.21 -0.2337 -0.9582 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B15 compound treatment 350200.0 -104000.0 -1.06 432960.0 -12800.0 -0.13 -0.8447 -0.7904 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B16 compound treatment 373310.0 -81200.0 -0.83 349280.0 -96500.0 -1.01 -1.2986 -0.9949 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B17 compound treatment 399750.0 -54800.0 -0.56 286020.0 -160000.0 -1.67 -1.5773 -0.8941 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B18 compound treatment 426000.0 -28500.0 -0.29 412260.0 -33500.0 -0.35 -0.4534 -0.9955 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B19 compound treatment 376160.0 -78400.0 -0.8 410530.0 -35300.0 -0.37 -0.8244 -0.939 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B20 mock treatment 400910.0 -53600.0 -0.54 366640.0 -79100.0 -0.83 -0.9717 -0.9793 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B21 compound treatment 398990.0 -55500.0 -0.56 382920.0 -62900.0 -0.66 -0.8649 -0.997 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B22 compound treatment 444500.0 -10000.0 -0.1 400600.0 -45200.0 -0.47 -0.4069 -0.8401 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B23 compound treatment 427600.0 -26900.0 -0.27 382110.0 -63700.0 -0.67 -0.6653 -0.9226 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 B24 compound treatment 447870.0 -6660.0 -0.07 406250.0 -39500.0 -0.41 -0.3408 -0.8119 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C01 compound treatment 405150.0 -49400.0 -0.5 398020.0 -47800.0 -0.5 -0.7087 -1.0 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C02 compound treatment 448110.0 -6420.0 -0.07 317230.0 -129000.0 -1.35 -0.9986 -0.7405 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C03 compound treatment 398140.0 -56400.0 -0.57 360820.0 -85000.0 -0.89 -1.0347 -0.9773 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C04 compound treatment 379240.0 -75300.0 -0.77 387000.0 -58800.0 -0.62 -0.9766 -0.9942 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C05 compound treatment 291130.0 -163000.0 -1.66 235970.0 -210000.0 -2.2 -2.7286 -0.9904 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C06 compound treatment 430470.0 -24100.0 -0.24 404020.0 -41800.0 -0.44 -0.4823 -0.9622 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C07 compound treatment 453070.0 -1460.0 -0.01 355230.0 -90600.0 -0.95 -0.6814 -0.7181 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C08 compound treatment 392600.0 -61900.0 -0.63 395480.0 -50300.0 -0.53 -0.8177 -0.9961 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C09 compound treatment 357760.0 -96800.0 -0.98 421880.0 -23900.0 -0.25 -0.8725 -0.8598 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C10 compound treatment 360000.0 -94500.0 -0.96 384380.0 -61400.0 -0.64 -1.1342 -0.981 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C11 mock treatment 372990.0 -81500.0 -0.83 386130.0 -59700.0 -0.63 -1.0279 -0.9903 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C12 mock treatment 420070.0 -34500.0 -0.35 372450.0 -73300.0 -0.77 -0.791 -0.9367 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C13 compound treatment 467840.0 13300.0 0.14 380180.0 -65600.0 -0.69 -0.3904 -0.5573 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C14 compound treatment 459580.0 5050.0 0.05 421450.0 -24300.0 -0.25 -0.144 -0.5538 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C15 mock treatment 429350.0 -25200.0 -0.26 446340.0 554.0 0.01 -0.1769 -0.6909 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C16 mock treatment 488660.0 34100.0 0.35 365150.0 -80600.0 -0.84 -0.3522 -0.3856 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C17 compound treatment 398240.0 -56300.0 -0.57 340640.0 -105000.0 -1.1 -1.1835 -0.9534 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C18 compound treatment 361380.0 -93200.0 -0.95 421010.0 -24800.0 -0.26 -0.8529 -0.8689 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C19 compound treatment 317360.0 -137000.0 -1.39 348480.0 -97300.0 -1.02 -1.7066 -0.9882 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C20 compound treatment 298510.0 -156000.0 -1.59 232350.0 -213000.0 -2.24 -2.7024 -0.9858 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C21 compound treatment 164220.0 -290000.0 -2.95 131230.0 -315000.0 -3.3 -4.4166 -0.9985 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C22 compound treatment 313940.0 -141000.0 -1.43 399710.0 -46100.0 -0.48 -1.3516 -0.8963 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C23 compound treatment 410600.0 -43900.0 -0.45 341920.0 -104000.0 -1.09 -1.0852 -0.9226 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 C24 compound treatment 344800.0 -110000.0 -1.12 314600.0 -131000.0 -1.37 -1.7604 -0.9946 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D01 compound treatment 424970.0 -29600.0 -0.3 466180.0 20400.0 0.21 -0.0613 -0.1664 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D02 compound treatment 325120.0 -129000.0 -1.32 365770.0 -80000.0 -0.84 -1.5227 -0.9764 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D03 compound treatment 404430.0 -50100.0 -0.51 462960.0 17200.0 0.18 -0.2328 -0.4311 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D04 mock treatment 425330.0 -29200.0 -0.3 406560.0 -39200.0 -0.41 -0.5005 -0.9872 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D05 compound treatment 455060.0 526.0 0.01 406880.0 -38900.0 -0.41 -0.2845 -0.6978 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D06 compound treatment 371440.0 -83100.0 -0.84 428040.0 -17700.0 -0.19 -0.7286 -0.8426 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D07 compound treatment 447140.0 -7390.0 -0.08 419680.0 -26100.0 -0.27 -0.2465 -0.8692 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D08 mock treatment 474830.0 20300.0 0.21 460320.0 14500.0 0.15 0.2535 0.9889 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D09 compound treatment 515200.0 60700.0 0.62 477800.0 32000.0 0.34 0.6731 0.9591 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D10 compound treatment 437130.0 -17400.0 -0.18 378110.0 -67700.0 -0.71 -0.6265 -0.8572 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D11 mock treatment 474890.0 20400.0 0.21 455800.0 10000.0 0.1 0.2205 0.9505 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D12 mock treatment 492250.0 37700.0 0.38 483130.0 37300.0 0.39 0.5477 0.9999 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D13 mock treatment 553210.0 98700.0 1.0 423360.0 -22400.0 -0.23 0.5429 0.5271 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D14 compound treatment 469920.0 15400.0 0.16 371080.0 -74700.0 -0.78 -0.4429 -0.5549 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D15 mock treatment 448550.0 -5980.0 -0.06 399370.0 -46400.0 -0.49 -0.3869 -0.7894 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D16 mock treatment 514830.0 60300.0 0.61 413480.0 -32300.0 -0.34 0.1939 0.277 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D17 compound treatment 435430.0 -19100.0 -0.19 370760.0 -75000.0 -0.79 -0.6931 -0.856 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D18 compound treatment 416480.0 -38100.0 -0.39 398110.0 -47700.0 -0.5 -0.6267 -0.992 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D19 compound treatment 19050.0 -435000.0 -4.43 10930.0 -435000.0 -4.56 -6.351 -0.9999 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D20 compound treatment 481640.0 27100.0 0.28 394300.0 -51500.0 -0.54 -0.1867 -0.3082 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D21 compound treatment 359890.0 -94600.0 -0.96 430690.0 -15100.0 -0.16 -0.7919 -0.8125 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D22 compound treatment 420990.0 -33500.0 -0.34 428190.0 -17600.0 -0.18 -0.3714 -0.9584 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D23 mock treatment 393960.0 -60600.0 -0.62 416480.0 -29300.0 -0.31 -0.6524 -0.9484 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 D24 compound treatment 397890.0 -56600.0 -0.58 452210.0 6420.0 0.07 -0.3594 -0.6202 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E01 mock treatment 455330.0 796.0 0.01 391440.0 -54300.0 -0.57 -0.3969 -0.697 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E02 mock treatment 402680.0 -51900.0 -0.53 512640.0 66900.0 0.7 0.1227 0.14 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E03 mock treatment 371600.0 -82900.0 -0.84 465120.0 19300.0 0.2 -0.4527 -0.5223 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E04 compound treatment 401280.0 -53300.0 -0.54 466460.0 20700.0 0.22 -0.2295 -0.3937 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E05 compound treatment 376360.0 -78200.0 -0.79 357920.0 -87900.0 -0.92 -1.2127 -0.9973 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E06 compound treatment 264570.0 -190000.0 -1.93 252650.0 -193000.0 -2.02 -2.7959 -0.9997 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E07 compound treatment 472510.0 18000.0 0.18 364710.0 -81100.0 -0.85 -0.4715 -0.5426 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E08 compound treatment 376360.0 -78200.0 -0.79 482560.0 36800.0 0.39 -0.2893 -0.3276 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E09 mock treatment 483840.0 29300.0 0.3 493760.0 48000.0 0.5 0.566 0.9688 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E10 mock treatment 386140.0 -68400.0 -0.7 469670.0 23900.0 0.25 -0.3145 -0.4258 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E11 compound treatment 336030.0 -119000.0 -1.2 289680.0 -156000.0 -1.64 -2.0081 -0.9887 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E12 compound treatment 568520.0 114000.0 1.16 462920.0 17100.0 0.18 0.946 0.8071 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E13 compound treatment 500000.0 45500.0 0.46 384160.0 -61600.0 -0.65 -0.1299 -0.1636 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E14 compound treatment 458190.0 3660.0 0.04 419520.0 -26300.0 -0.28 -0.1683 -0.6062 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E15 compound treatment 355530.0 -99000.0 -1.01 261450.0 -184000.0 -1.93 -2.0771 -0.9538 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E16 compound treatment 372490.0 -82000.0 -0.83 361670.0 -84100.0 -0.88 -1.2127 -0.9996 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E17 mock treatment 484800.0 30300.0 0.31 478210.0 32400.0 0.34 0.4577 0.9988 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E18 mock treatment 457440.0 2910.0 0.03 420320.0 -25500.0 -0.27 -0.1678 -0.625 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E19 compound treatment 401690.0 -52800.0 -0.54 453170.0 7380.0 0.08 -0.325 -0.599 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E20 compound treatment 498780.0 44200.0 0.45 373010.0 -72800.0 -0.76 -0.2212 -0.2499 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E21 mock treatment 397690.0 -56800.0 -0.58 492500.0 46700.0 0.49 -0.0624 -0.0824 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E22 compound treatment 414980.0 -39600.0 -0.4 408980.0 -36800.0 -0.39 -0.5569 -0.9998 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E23 compound treatment 377130.0 -77400.0 -0.79 386890.0 -58900.0 -0.62 -0.9925 -0.9928 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 E24 mock treatment 451840.0 -2690.0 -0.03 397120.0 -48700.0 -0.51 -0.3799 -0.744 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F01 mock treatment 479760.0 25200.0 0.26 415140.0 -30600.0 -0.32 -0.0458 -0.1114 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F02 mock treatment 392970.0 -61600.0 -0.63 505130.0 59300.0 0.62 -0.0027 -0.0031 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F03 compound treatment 414320.0 -40200.0 -0.41 418140.0 -27600.0 -0.29 -0.4938 -0.9858 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F04 compound treatment 435330.0 -19200.0 -0.2 413920.0 -31900.0 -0.33 -0.3741 -0.9673 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F05 compound treatment 392680.0 -61900.0 -0.63 346580.0 -99200.0 -1.04 -1.1795 -0.971 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F06 mock treatment 449540.0 -4990.0 -0.05 509760.0 64000.0 0.67 0.4381 0.6517 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F07 compound treatment 499610.0 45100.0 0.46 436510.0 -9280.0 -0.1 0.2552 0.545 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F08 compound treatment 462370.0 7840.0 0.08 373790.0 -72000.0 -0.75 -0.4771 -0.629 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F09 mock treatment 411220.0 -43300.0 -0.44 472510.0 26700.0 0.28 -0.1133 -0.2171 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F10 mock treatment 502200.0 47700.0 0.48 481600.0 35800.0 0.38 0.6078 0.992 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F11 mock treatment 398000.0 -56500.0 -0.57 421680.0 -24100.0 -0.25 -0.5848 -0.9319 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F12 compound treatment 362680.0 -91900.0 -0.93 249470.0 -196000.0 -2.06 -2.1145 -0.9361 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F13 compound treatment 511330.0 56800.0 0.58 370400.0 -75400.0 -0.79 -0.1504 -0.1537 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F14 compound treatment 127010.0 -328000.0 -3.33 74010.0 -372000.0 -3.9 -5.1079 -0.9969 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F15 compound treatment 399840.0 -54700.0 -0.56 346320.0 -99500.0 -1.04 -1.1299 -0.9567 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F16 compound treatment 492440.0 37900.0 0.39 451140.0 5350.0 0.06 0.312 0.8016 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F17 mock treatment 510630.0 56100.0 0.57 493000.0 47200.0 0.49 0.7529 0.9975 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F18 mock treatment 462040.0 7510.0 0.08 418400.0 -27400.0 -0.29 -0.149 -0.5017 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F19 compound treatment 402030.0 -52500.0 -0.53 418500.0 -27300.0 -0.29 -0.5794 -0.9572 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F20 compound treatment 414630.0 -39900.0 -0.41 421340.0 -24400.0 -0.26 -0.4679 -0.9754 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F21 compound treatment 427250.0 -27300.0 -0.28 409530.0 -36300.0 -0.38 -0.4647 -0.988 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F22 compound treatment 426400.0 -28100.0 -0.29 333130.0 -113000.0 -1.18 -1.0368 -0.8537 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F23 compound treatment 446820.0 -7710.0 -0.08 391720.0 -54100.0 -0.57 -0.456 -0.7974 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 F24 compound treatment 401310.0 -53200.0 -0.54 470670.0 24900.0 0.26 -0.1981 -0.3299 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G01 compound treatment 481170.0 26600.0 0.27 426800.0 -19000.0 -0.2 0.0507 0.151 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G02 mock treatment 370880.0 -83700.0 -0.85 455840.0 10100.0 0.11 -0.5266 -0.6148 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G03 mock treatment 476480.0 21900.0 0.22 436480.0 -9310.0 -0.1 0.0888 0.3646 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G04 mock treatment 347650.0 -107000.0 -1.09 515640.0 69900.0 0.73 -0.2505 -0.1913 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G05 compound treatment 411290.0 -43200.0 -0.44 410670.0 -35100.0 -0.37 -0.5709 -0.9961 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G06 compound treatment 514460.0 59900.0 0.61 432500.0 -13300.0 -0.14 0.3322 0.5318 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G07 compound treatment 440520.0 -14000.0 -0.14 416080.0 -29700.0 -0.31 -0.3208 -0.9372 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G08 mock treatment 422290.0 -32200.0 -0.33 444640.0 -1150.0 -0.01 -0.2402 -0.7325 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G09 compound treatment 405080.0 -49500.0 -0.5 440570.0 -5220.0 -0.05 -0.394 -0.7794 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G10 compound treatment 406370.0 -48200.0 -0.49 430690.0 -15100.0 -0.16 -0.4579 -0.8903 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G11 mock treatment 488110.0 33600.0 0.34 332930.0 -113000.0 -1.18 -0.5949 -0.4833 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G12 compound treatment 520130.0 65600.0 0.67 426430.0 -19400.0 -0.2 0.3279 0.4707 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G13 compound treatment 469760.0 15200.0 0.15 335840.0 -110000.0 -1.15 -0.7052 -0.6067 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G14 compound treatment 383400.0 -71100.0 -0.72 283810.0 -162000.0 -1.7 -1.7112 -0.9276 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G15 compound treatment 355060.0 -99500.0 -1.01 373360.0 -72400.0 -0.76 -1.2514 -0.99 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G16 compound treatment 436130.0 -18400.0 -0.19 379630.0 -66200.0 -0.69 -0.6224 -0.8669 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G17 mock treatment 448730.0 -5800.0 -0.06 438370.0 -7420.0 -0.08 -0.0966 -0.9908 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G18 compound treatment 185280.0 -269000.0 -2.74 128000.0 -318000.0 -3.33 -4.2892 -0.9952 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G19 mock treatment 483210.0 28700.0 0.29 537200.0 91400.0 0.96 0.8833 0.8823 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G20 mock treatment 417620.0 -36900.0 -0.38 497470.0 51700.0 0.54 0.1177 0.1786 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G21 compound treatment 496500.0 42000.0 0.43 459050.0 13300.0 0.14 0.3998 0.8914 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G22 compound treatment 422580.0 -32000.0 -0.32 403360.0 -42400.0 -0.44 -0.5439 -0.9881 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G23 compound treatment 469070.0 14500.0 0.15 416280.0 -29500.0 -0.31 -0.1142 -0.3332 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 G24 compound treatment 443800.0 -10700.0 -0.11 395530.0 -50300.0 -0.53 -0.4495 -0.8358 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H01 compound treatment 408070.0 -46500.0 -0.47 423890.0 -21900.0 -0.23 -0.4961 -0.945 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H02 compound treatment 352050.0 -102000.0 -1.04 426170.0 -19600.0 -0.21 -0.8817 -0.8306 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H03 mock treatment 417020.0 -37500.0 -0.38 380120.0 -65700.0 -0.69 -0.7561 -0.9612 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H04 mock treatment 398120.0 -56400.0 -0.57 277890.0 -168000.0 -1.76 -1.6493 -0.8914 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H05 compound treatment 391130.0 -63400.0 -0.64 292020.0 -154000.0 -1.61 -1.5948 -0.9191 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H06 compound treatment 417560.0 -37000.0 -0.38 431360.0 -14400.0 -0.15 -0.3726 -0.9199 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H07 compound treatment 337160.0 -117000.0 -1.19 362880.0 -82900.0 -0.87 -1.4576 -0.9879 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H08 compound treatment 544430.0 89900.0 0.91 405710.0 -40100.0 -0.42 0.3491 0.3472 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H09 compound treatment 465310.0 10800.0 0.11 450400.0 4610.0 0.05 0.1116 0.9325 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H10 compound treatment 361120.0 -93400.0 -0.95 418640.0 -27100.0 -0.28 -0.8724 -0.8803 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H11 compound treatment 485190.0 30700.0 0.31 401210.0 -44600.0 -0.47 -0.11 -0.1959 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H12 compound treatment 356320.0 -98200.0 -1.0 387890.0 -57900.0 -0.61 -1.1347 -0.9715 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H13 mock treatment 430510.0 -24000.0 -0.24 541120.0 95300.0 1.0 0.5337 0.519 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H14 compound treatment 17070.0 -437000.0 -4.45 11640.0 -434000.0 -4.55 -6.36 -0.9999 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H15 compound treatment 368960.0 -85600.0 -0.87 461990.0 16200.0 0.17 -0.4949 -0.5585 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H16 compound treatment 520640.0 66100.0 0.67 511460.0 65700.0 0.69 0.9616 0.9999 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H17 compound treatment 371750.0 -82800.0 -0.84 399910.0 -45900.0 -0.48 -0.9347 -0.9648 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H18 compound treatment 454560.0 25.7 0.0 394720.0 -51100.0 -0.54 -0.3781 -0.7068 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H19 mock treatment 431410.0 -23100.0 -0.23 473230.0 27400.0 0.29 0.0372 0.1001 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H20 mock treatment 424280.0 -30300.0 -0.31 459960.0 14200.0 0.15 -0.1124 -0.3292 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H21 compound treatment 15970.0 -439000.0 -4.46 12730.0 -433000.0 -4.54 -6.3598 -1.0 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H22 compound treatment 408570.0 -46000.0 -0.47 451320.0 5530.0 0.06 -0.2893 -0.6146 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H23 mock treatment 434590.0 -19900.0 -0.2 422720.0 -23100.0 -0.24 -0.3142 -0.9962 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 H24 compound treatment 402560.0 -52000.0 -0.53 414420.0 -31400.0 -0.33 -0.6059 -0.9739 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I01 compound treatment 383840.0 -70700.0 -0.72 417210.0 -28600.0 -0.3 -0.7197 -0.9247 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I02 compound treatment 244830.0 -210000.0 -2.13 310140.0 -136000.0 -1.42 -2.5118 -0.9806 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I03 compound treatment 490130.0 35600.0 0.36 388930.0 -56900.0 -0.6 -0.1654 -0.2374 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I04 mock treatment 463900.0 9370.0 0.1 528710.0 82900.0 0.87 0.6817 0.7799 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I05 mock treatment 429630.0 -24900.0 -0.25 371150.0 -74600.0 -0.78 -0.7319 -0.8905 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I06 mock treatment 527860.0 73300.0 0.75 450590.0 4800.0 0.05 0.5625 0.7532 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I07 compound treatment 446470.0 -8060.0 -0.08 485640.0 39900.0 0.42 0.2373 0.5577 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I08 compound treatment 416380.0 -38200.0 -0.39 399160.0 -46600.0 -0.49 -0.6196 -0.9934 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I09 compound treatment 401980.0 -52600.0 -0.53 527550.0 81800.0 0.86 0.2281 0.226 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I10 compound treatment 475070.0 20500.0 0.21 492090.0 46300.0 0.49 0.4906 0.929 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I11 compound treatment 424030.0 -30500.0 -0.31 485360.0 39600.0 0.41 0.074 0.1429 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I12 compound treatment 484860.0 30300.0 0.31 469380.0 23600.0 0.25 0.3927 0.994 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I13 compound treatment 57060.0 -397000.0 -4.04 36960.0 -409000.0 -4.28 -5.885 -0.9996 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I14 compound treatment 27780.0 -427000.0 -4.34 37350.0 -408000.0 -4.28 -6.0925 -1.0 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I15 compound treatment 515530.0 61000.0 0.62 473200.0 27400.0 0.29 0.6414 0.9389 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I16 compound treatment 397990.0 -56500.0 -0.57 460120.0 14300.0 0.15 -0.3001 -0.5053 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I17 compound treatment 511770.0 57200.0 0.58 526150.0 80400.0 0.84 1.0067 0.9837 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I18 compound treatment 427580.0 -27000.0 -0.27 497920.0 52100.0 0.55 0.1926 0.3151 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I19 compound treatment 463240.0 8710.0 0.09 411170.0 -34600.0 -0.36 -0.1939 -0.5194 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I20 compound treatment 458530.0 4000.0 0.04 470470.0 24700.0 0.26 0.2116 0.8082 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I21 mock treatment 511620.0 57100.0 0.58 422470.0 -23300.0 -0.24 0.2375 0.3773 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I22 mock treatment 460530.0 6000.0 0.06 435450.0 -10300.0 -0.11 -0.0335 -0.2695 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I23 compound treatment 246760.0 -208000.0 -2.11 250730.0 -195000.0 -2.04 -2.9381 -0.9999 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 I24 compound treatment 414620.0 -39900.0 -0.41 460000.0 14200.0 0.15 -0.1815 -0.4201 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J01 compound treatment 443150.0 -11400.0 -0.12 391470.0 -54300.0 -0.57 -0.4842 -0.8338 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J02 compound treatment 263680.0 -191000.0 -1.94 279460.0 -166000.0 -1.74 -2.6037 -0.9986 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J03 compound treatment 413090.0 -41400.0 -0.42 339040.0 -107000.0 -1.12 -1.0887 -0.9109 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J04 mock treatment 528970.0 74400.0 0.76 450900.0 5110.0 0.05 0.5728 0.7553 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J05 mock treatment 434210.0 -20300.0 -0.21 373560.0 -72200.0 -0.76 -0.6811 -0.8683 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J06 mock treatment 361890.0 -92600.0 -0.94 360000.0 -85800.0 -0.9 -1.3013 -0.9997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J07 compound treatment 370630.0 -83900.0 -0.85 424210.0 -21600.0 -0.23 -0.7628 -0.8647 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J08 compound treatment 432820.0 -21700.0 -0.22 525620.0 79800.0 0.84 0.4354 0.5033 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J09 compound treatment 569870.0 115000.0 1.17 463010.0 17200.0 0.18 0.9564 0.8065 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J10 compound treatment 345530.0 -109000.0 -1.11 310880.0 -135000.0 -1.41 -1.7828 -0.9927 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J11 compound treatment 343680.0 -111000.0 -1.13 396450.0 -49300.0 -0.52 -1.1621 -0.9376 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J12 compound treatment 387270.0 -67300.0 -0.68 418320.0 -27500.0 -0.29 -0.6868 -0.9261 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J13 compound treatment 7140.0 -447000.0 -4.55 7520.0 -438000.0 -4.59 -6.4618 -1.0 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J14 compound treatment 30080.0 -424000.0 -4.31 24130.0 -422000.0 -4.42 -6.1739 -0.9999 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J15 compound treatment 434990.0 -19500.0 -0.2 423200.0 -22600.0 -0.24 -0.3078 -0.9962 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J16 mock treatment 499800.0 45300.0 0.46 505710.0 59900.0 0.63 0.7692 0.9883 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J17 compound treatment 20320.0 -434000.0 -4.41 24360.0 -421000.0 -4.42 -6.2424 -1.0 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J18 mock treatment 528370.0 73800.0 0.75 416700.0 -29100.0 -0.3 0.3151 0.389 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J19 compound treatment 483520.0 29000.0 0.29 565120.0 119000.0 1.25 1.0924 0.8504 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J20 compound treatment 385880.0 -68700.0 -0.7 450610.0 4820.0 0.05 -0.4576 -0.6542 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J21 mock treatment 447260.0 -7270.0 -0.07 437790.0 -8000.0 -0.08 -0.1115 -0.9981 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J22 mock treatment 394450.0 -60100.0 -0.61 438880.0 -6910.0 -0.07 -0.4829 -0.7854 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J23 compound treatment 425300.0 -29200.0 -0.3 446150.0 364.0 0.0 -0.2074 -0.698 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 J24 compound treatment 463600.0 9070.0 0.09 398720.0 -47100.0 -0.49 -0.2836 -0.5652 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K01 compound treatment 460850.0 6320.0 0.06 425340.0 -20400.0 -0.21 -0.1061 -0.4744 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K02 compound treatment 353480.0 -101000.0 -1.03 392730.0 -53100.0 -0.56 -1.1192 -0.9585 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K03 compound treatment 469640.0 15100.0 0.15 415680.0 -30100.0 -0.32 -0.1145 -0.3264 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K04 mock treatment 382660.0 -71900.0 -0.73 448320.0 2530.0 0.03 -0.4977 -0.681 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K05 compound treatment 332650.0 -122000.0 -1.24 368250.0 -77500.0 -0.81 -1.4503 -0.9791 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K06 compound treatment 364650.0 -89900.0 -0.91 465680.0 19900.0 0.21 -0.4985 -0.5321 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K07 mock treatment 661520.0 207000.0 2.1 393150.0 -52600.0 -0.55 1.0974 0.5047 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K08 mock treatment 535300.0 80800.0 0.82 452080.0 6290.0 0.07 0.627 0.7615 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K09 compound treatment 375250.0 -79300.0 -0.81 387850.0 -57900.0 -0.61 -0.9989 -0.9903 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K10 compound treatment 361700.0 -92800.0 -0.94 420860.0 -24900.0 -0.26 -0.8517 -0.8701 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K11 compound treatment 432960.0 -21600.0 -0.22 451430.0 5640.0 0.06 -0.1132 -0.4986 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K12 compound treatment 474100.0 19600.0 0.2 421760.0 -24000.0 -0.25 -0.0374 -0.1166 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K13 mock treatment 494720.0 40200.0 0.41 509410.0 63600.0 0.67 0.7601 0.9723 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K14 compound treatment 504430.0 49900.0 0.51 431560.0 -14200.0 -0.15 0.2531 0.479 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K15 mock treatment 472590.0 18100.0 0.18 492540.0 46800.0 0.49 0.4761 0.9102 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K16 mock treatment 541560.0 87000.0 0.88 529440.0 83700.0 0.88 1.2451 1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K17 compound treatment 388550.0 -66000.0 -0.67 431920.0 -13900.0 -0.15 -0.5769 -0.8408 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K18 compound treatment 519230.0 64700.0 0.66 496060.0 50300.0 0.53 0.8374 0.994 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K19 compound treatment 407760.0 -46800.0 -0.48 485030.0 39200.0 0.41 -0.0454 -0.0722 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K20 compound treatment 484590.0 30100.0 0.31 387620.0 -58200.0 -0.61 -0.215 -0.3153 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K21 mock treatment 433140.0 -21400.0 -0.22 475230.0 29400.0 0.31 0.0644 0.1707 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K22 compound treatment 475040.0 20500.0 0.21 451630.0 5840.0 0.06 0.1906 0.8778 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K23 mock treatment 449360.0 -5170.0 -0.05 498660.0 52900.0 0.55 0.3546 0.6371 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 K24 mock treatment 425700.0 -28800.0 -0.29 460160.0 14400.0 0.15 -0.1007 -0.3057 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L01 mock treatment 476260.0 21700.0 0.22 504060.0 58300.0 0.61 0.5879 0.9054 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L02 compound treatment 312410.0 -142000.0 -1.44 312480.0 -133000.0 -1.4 -2.0089 -0.9999 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L03 mock treatment 457070.0 2540.0 0.03 401690.0 -44100.0 -0.46 -0.3085 -0.6666 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L04 mock treatment 541540.0 87000.0 0.88 418720.0 -27100.0 -0.28 0.4247 0.4574 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L05 compound treatment 382680.0 -71900.0 -0.73 366350.0 -79400.0 -0.83 -1.1048 -0.9979 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L06 compound treatment 383790.0 -70700.0 -0.72 358660.0 -87100.0 -0.91 -1.1538 -0.993 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L07 mock treatment 557730.0 103000.0 1.05 428920.0 -16900.0 -0.18 0.6166 0.5798 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L08 mock treatment 426330.0 -28200.0 -0.29 401980.0 -43800.0 -0.46 -0.5272 -0.9743 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L09 compound treatment 428760.0 -25800.0 -0.26 373030.0 -72800.0 -0.76 -0.7242 -0.8985 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L10 compound treatment 522170.0 67600.0 0.69 460810.0 15000.0 0.16 0.5973 0.8471 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L11 compound treatment 523680.0 69100.0 0.7 426400.0 -19400.0 -0.2 0.3532 0.4829 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L12 compound treatment 470080.0 15500.0 0.16 467470.0 21700.0 0.23 0.2724 0.9842 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L13 compound treatment 12590.0 -442000.0 -4.49 11750.0 -434000.0 -4.55 -6.3913 -1.0 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L14 compound treatment 30780.0 -424000.0 -4.31 11070.0 -435000.0 -4.55 -6.2657 -0.9996 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L15 mock treatment 503080.0 48500.0 0.49 495270.0 49500.0 0.52 0.7155 0.9997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L16 mock treatment 488450.0 33900.0 0.34 469050.0 23300.0 0.24 0.4161 0.9856 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L17 compound treatment 319320.0 -135000.0 -1.37 255220.0 -191000.0 -2.0 -2.3835 -0.9834 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L18 compound treatment 143810.0 -311000.0 -3.16 125560.0 -320000.0 -3.36 -4.6052 -0.9995 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L19 compound treatment 479430.0 24900.0 0.25 432910.0 -12900.0 -0.13 0.0835 0.2912 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L20 mock treatment 462500.0 7970.0 0.08 570120.0 124000.0 1.3 0.9784 0.7496 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L21 compound treatment 408960.0 -45600.0 -0.46 423280.0 -22500.0 -0.24 -0.4942 -0.951 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L22 compound treatment 429790.0 -24700.0 -0.25 431280.0 -14500.0 -0.15 -0.2853 -0.9709 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L23 mock treatment 425720.0 -28800.0 -0.29 473060.0 27300.0 0.29 -0.005 -0.0122 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 L24 mock treatment 373550.0 -81000.0 -0.82 448360.0 2570.0 0.03 -0.5629 -0.6836 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M01 mock treatment 462990.0 8460.0 0.09 498350.0 52600.0 0.55 0.4502 0.8077 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M02 compound treatment 504880.0 50300.0 0.51 415460.0 -30300.0 -0.32 0.1371 0.2276 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M03 compound treatment 457510.0 2980.0 0.03 386750.0 -59000.0 -0.62 -0.416 -0.6717 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M04 compound treatment 428830.0 -25700.0 -0.26 418330.0 -27500.0 -0.29 -0.3881 -0.9988 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M05 compound treatment 404740.0 -49800.0 -0.51 362430.0 -83400.0 -0.87 -0.9754 -0.9663 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M06 compound treatment 368690.0 -85800.0 -0.87 356000.0 -89800.0 -0.94 -1.282 -0.9993 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M07 compound treatment 442250.0 -12300.0 -0.12 409230.0 -36600.0 -0.38 -0.3591 -0.8914 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M08 compound treatment 382560.0 -72000.0 -0.73 443570.0 -2220.0 -0.02 -0.5336 -0.7292 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M09 mock treatment 534520.0 80000.0 0.81 425620.0 -20200.0 -0.21 0.4254 0.5065 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M10 mock treatment 552770.0 98200.0 1.0 514400.0 68600.0 0.72 1.2142 0.987 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M11 compound treatment 426170.0 -28400.0 -0.29 457160.0 11400.0 0.12 -0.1195 -0.3833 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M12 compound treatment 441010.0 -13500.0 -0.14 409120.0 -36700.0 -0.38 -0.3688 -0.904 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M13 mock treatment 487560.0 33000.0 0.34 497200.0 51400.0 0.54 0.6182 0.9741 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M14 mock treatment 562490.0 108000.0 1.1 456200.0 10400.0 0.11 0.8529 0.7736 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M15 mock treatment 546080.0 91500.0 0.93 474090.0 28300.0 0.3 0.8675 0.8885 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M16 mock treatment 506740.0 52200.0 0.53 477600.0 31800.0 0.33 0.6108 0.9749 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M17 compound treatment 527760.0 73200.0 0.74 450040.0 4250.0 0.04 0.5577 0.7481 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M18 compound treatment 525010.0 70500.0 0.72 510880.0 65100.0 0.68 0.9887 0.9997 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M19 compound treatment 521820.0 67300.0 0.68 482400.0 36600.0 0.38 0.7548 0.9627 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M20 compound treatment 438190.0 -16300.0 -0.17 378270.0 -67500.0 -0.71 -0.6177 -0.85 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M21 compound treatment 457990.0 3460.0 0.04 476090.0 30300.0 0.32 0.2493 0.7806 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M22 compound treatment 433700.0 -20800.0 -0.21 460210.0 14400.0 0.15 -0.0428 -0.1647 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M23 compound treatment 414690.0 -39800.0 -0.4 444240.0 -1550.0 -0.02 -0.2978 -0.7348 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 M24 compound treatment 395130.0 -59400.0 -0.6 405150.0 -40600.0 -0.43 -0.7279 -0.9854 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N01 compound treatment 388430.0 -66100.0 -0.67 455630.0 9840.0 0.1 -0.4021 -0.5916 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N02 mock treatment 453250.0 -1280.0 -0.01 466650.0 20900.0 0.22 0.1453 0.6637 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N03 compound treatment 482270.0 27700.0 0.28 465780.0 20000.0 0.21 0.3474 0.9893 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N04 compound treatment 277160.0 -177000.0 -1.8 233090.0 -213000.0 -2.23 -2.8504 -0.9945 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N05 compound treatment 258160.0 -196000.0 -2.0 214530.0 -231000.0 -2.42 -3.1244 -0.9954 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N06 compound treatment 445810.0 -8720.0 -0.09 439530.0 -6260.0 -0.07 -0.109 -0.989 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N07 compound treatment 455480.0 946.0 0.01 374930.0 -70900.0 -0.74 -0.5182 -0.6979 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N08 compound treatment 409360.0 -45200.0 -0.46 419840.0 -25900.0 -0.27 -0.5168 -0.9687 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N09 mock treatment 469030.0 14500.0 0.15 462420.0 16600.0 0.17 0.2274 0.9965 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N10 mock treatment 550450.0 95900.0 0.97 481180.0 35400.0 0.37 0.9514 0.9123 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N11 mock treatment 550350.0 95800.0 0.97 459910.0 14100.0 0.15 0.7931 0.8053 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N12 compound treatment 420530.0 -34000.0 -0.35 353730.0 -92100.0 -0.96 -0.9264 -0.9042 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N13 mock treatment 435840.0 -18700.0 -0.19 478010.0 32200.0 0.34 0.1044 0.2695 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N14 mock treatment 484960.0 30400.0 0.31 438280.0 -7510.0 -0.08 0.163 0.511 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N15 compound treatment 554740.0 100000.0 1.02 460960.0 15200.0 0.16 0.8325 0.8077 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N16 compound treatment 225600.0 -229000.0 -2.33 194720.0 -251000.0 -2.63 -3.5051 -0.9981 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N17 compound treatment 514360.0 59800.0 0.61 486690.0 40900.0 0.43 0.7329 0.9854 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N18 compound treatment 501330.0 46800.0 0.48 472370.0 26600.0 0.28 0.5332 0.9675 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N19 compound treatment 456670.0 2140.0 0.02 466300.0 20500.0 0.21 0.1673 0.7746 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N20 compound treatment 411560.0 -43000.0 -0.44 436650.0 -9140.0 -0.1 -0.3765 -0.8421 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N21 mock treatment 457890.0 3360.0 0.03 510560.0 64800.0 0.68 0.504 0.7417 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N22 compound treatment 467430.0 12900.0 0.13 391690.0 -54100.0 -0.57 -0.3081 -0.5296 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N23 compound treatment 400120.0 -54400.0 -0.55 469060.0 23300.0 0.24 -0.2186 -0.3617 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 N24 mock treatment 425670.0 -28900.0 -0.29 336280.0 -110000.0 -1.15 -1.0187 -0.8602 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O01 compound treatment 338020.0 -117000.0 -1.18 329790.0 -116000.0 -1.22 -1.6966 -0.9999 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O02 compound treatment 419840.0 -34700.0 -0.35 430480.0 -15300.0 -0.16 -0.3627 -0.9364 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O03 compound treatment 369930.0 -84600.0 -0.86 383200.0 -62600.0 -0.66 -1.0716 -0.9911 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O04 compound treatment 351520.0 -103000.0 -1.05 358160.0 -87600.0 -0.92 -1.3894 -0.9979 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O05 compound treatment 319520.0 -135000.0 -1.37 332130.0 -114000.0 -1.19 -1.8122 -0.9975 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O06 compound treatment 400960.0 -53600.0 -0.54 390130.0 -55700.0 -0.58 -0.7973 -0.9994 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O07 mock treatment 359150.0 -95400.0 -0.97 478400.0 32600.0 0.34 -0.4438 -0.4318 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O08 mock treatment 478420.0 23900.0 0.24 513670.0 67900.0 0.71 0.6746 0.8976 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O09 mock treatment 573330.0 119000.0 1.21 423760.0 -22000.0 -0.23 0.6904 0.5618 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O10 compound treatment 460390.0 5860.0 0.06 444360.0 -1430.0 -0.01 0.0315 0.5137 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O11 mock treatment 512610.0 58100.0 0.59 474150.0 28400.0 0.3 0.6275 0.9496 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O12 mock treatment 533040.0 78500.0 0.8 440070.0 -5720.0 -0.06 0.5218 0.6522 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O13 compound treatment 33880.0 -421000.0 -4.27 27390.0 -418000.0 -4.38 -6.1225 -0.9999 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O14 compound treatment 22920.0 -432000.0 -4.39 18620.0 -427000.0 -4.48 -6.2662 -0.9999 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O15 compound treatment 491480.0 36900.0 0.38 541480.0 95700.0 1.0 0.9745 0.9102 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O16 compound treatment 173240.0 -281000.0 -2.86 141500.0 -304000.0 -3.19 -4.2757 -0.9985 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O17 compound treatment 413680.0 -40900.0 -0.42 471010.0 25200.0 0.26 -0.1067 -0.2168 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O18 compound treatment 451840.0 -2690.0 -0.03 405310.0 -40500.0 -0.42 -0.3192 -0.7512 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O19 compound treatment 497600.0 43100.0 0.44 521670.0 75900.0 0.8 0.8717 0.9604 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O20 mock treatment 465140.0 10600.0 0.11 456220.0 10400.0 0.11 0.1535 1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O21 mock treatment 426560.0 -28000.0 -0.28 419060.0 -26700.0 -0.28 -0.399 -1.0 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O22 compound treatment 390020.0 -64500.0 -0.66 441860.0 -3930.0 -0.04 -0.4927 -0.75 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O23 compound treatment 365980.0 -88600.0 -0.9 380690.0 -65100.0 -0.68 -1.1186 -0.9907 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 O24 compound treatment 439600.0 -14900.0 -0.15 433940.0 -11800.0 -0.12 -0.1951 -0.995 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P01 compound treatment 438450.0 -16100.0 -0.16 315400.0 -130000.0 -1.37 -1.0816 -0.7861 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P02 mock treatment 392980.0 -61600.0 -0.63 412320.0 -33500.0 -0.35 -0.6902 -0.9626 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P03 mock treatment 371770.0 -82800.0 -0.84 396650.0 -49100.0 -0.51 -0.9588 -0.9723 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P04 compound treatment 333600.0 -121000.0 -1.23 300640.0 -145000.0 -1.52 -1.9443 -0.9944 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P05 compound treatment 241030.0 -214000.0 -2.17 241890.0 -204000.0 -2.14 -3.0448 -1.0 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P06 compound treatment 362770.0 -91800.0 -0.93 315890.0 -130000.0 -1.36 -1.6218 -0.983 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P07 compound treatment 413090.0 -41400.0 -0.42 399310.0 -46500.0 -0.49 -0.6421 -0.9974 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P08 compound treatment 306520.0 -148000.0 -1.5 276000.0 -170000.0 -1.78 -2.3215 -0.9965 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P09 mock treatment 365940.0 -88600.0 -0.9 381440.0 -64300.0 -0.67 -1.1133 -0.9898 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P10 compound treatment 348820.0 -106000.0 -1.07 401280.0 -44500.0 -0.47 -1.0894 -0.9302 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P11 mock treatment 488390.0 33900.0 0.34 415060.0 -30700.0 -0.32 0.0156 0.0332 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P12 mock treatment 413770.0 -40800.0 -0.41 395000.0 -50800.0 -0.53 -0.6692 -0.9923 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P13 compound treatment 399310.0 -55200.0 -0.56 372840.0 -72900.0 -0.76 -0.9373 -0.9885 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P14 compound treatment 16740.0 -438000.0 -4.45 18080.0 -428000.0 -4.48 -6.3146 -1.0 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P15 compound treatment 380010.0 -74500.0 -0.76 408810.0 -37000.0 -0.39 -0.8095 -0.9516 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P16 compound treatment 393000.0 -61500.0 -0.63 406880.0 -38900.0 -0.41 -0.7304 -0.9785 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P17 compound treatment 405370.0 -49200.0 -0.5 409920.0 -35900.0 -0.38 -0.619 -0.9901 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P18 compound treatment 388440.0 -66100.0 -0.67 398080.0 -47700.0 -0.5 -0.8284 -0.9894 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P19 compound treatment 409810.0 -44700.0 -0.45 423860.0 -21900.0 -0.23 -0.4838 -0.9501 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P20 mock treatment 429310.0 -25200.0 -0.26 395610.0 -50200.0 -0.53 -0.553 -0.9455 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P21 compound treatment 385400.0 -69100.0 -0.7 366370.0 -79400.0 -0.83 -1.0851 -0.9965 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P22 compound treatment 174590.0 -280000.0 -2.84 185280.0 -261000.0 -2.73 -3.9416 -0.9998 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P23 compound treatment 388960.0 -65600.0 -0.67 428570.0 -17200.0 -0.18 -0.5987 -0.8673 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.2284 P24 mock treatment 351080.0 -103000.0 -1.05 321390.0 -124000.0 -1.3 -1.665 -0.9943 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A01 mock treatment 469760.0 46500.0 0.47 418130.0 11700.0 0.12 -0.0644 -0.0907 413730.0 -33500.952380952 -0.311142923472089 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A02 mock treatment 401090.0 -22200.0 -0.23 435680.0 29200.0 0.31 0.3301 0.4319 438770.0 -8460.95238095202 -0.078581809532805 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A03 mock treatment 338260.0 -85000.0 -0.86 459320.0 52900.0 0.55 -0.3108 -0.2812 456880.0 9649.04761904798 0.089616344358586 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A04 mock treatment 383810.0 -39500.0 -0.4 383420.0 -23000.0 -0.24 -0.5405 -0.962 425060.0 -22170.952380952 -0.205914591965216 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A05 mock treatment 409870.0 -13400.0 -0.14 431930.0 25500.0 0.27 -0.7599 -0.5945 390910.0 -56320.952380952 -0.523085599993433 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A06 mock treatment 378240.0 -45000.0 -0.46 384320.0 -22100.0 -0.23 -0.6205 -0.7988 450580.0 3349.04761904798 0.0311045624968652 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A07 mock treatment 318660.0 -105000.0 -1.06 448530.0 42100.0 0.44 -1.131 -0.6489 312700.0 -134530.952380952 -1.24946757767679 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A08 mock treatment 341460.0 -81800.0 -0.83 412730.0 6260.0 0.07 -0.4367 -0.4704 471940.0 24709.047619048 0.229487365761366 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A09 mock treatment 466160.0 42900.0 0.44 424410.0 17900.0 0.19 -0.0031 -0.0044 392770.0 -54460.952380952 -0.505810692967592 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A10 mock treatment 430930.0 7650.0 0.08 475870.0 69400.0 0.73 0.1574 0.1926 429500.0 -17730.952380952 -0.164677717129337 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A11 mock treatment 359680.0 -63600.0 -0.65 380980.0 -25500.0 -0.27 -1.0679 -0.9069 410950.0 -36280.952380952 -0.336962408166626 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A12 mock treatment 363390.0 -59900.0 -0.61 411300.0 4830.0 0.05 -0.9903 -0.7894 403730.0 -43500.952380952 -0.404018767697042 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A13 mock treatment 414830.0 -8450.0 -0.09 411520.0 5050.0 0.05 -0.3292 -0.7041 404930.0 -42300.952380952 -0.392873666390048 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A14 mock treatment 405760.0 -17500.0 -0.18 350840.0 -55600.0 -0.58 -0.3527 -0.4161 405460.0 -41770.952380952 -0.387951246646125 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A15 mock treatment 387370.0 -35900.0 -0.36 475490.0 69000.0 0.72 0.0691 0.0837 433310.0 -13920.952380952 -0.12929202047963 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A16 mock treatment 406880.0 -16400.0 -0.17 314030.0 -92400.0 -0.97 -1.1066 -0.8889 385090.0 -62140.952380952 -0.577139341332356 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A17 mock treatment 367200.0 -56100.0 -0.57 387250.0 -19200.0 -0.2 -0.5188 -0.7987 421830.0 -25400.952380952 -0.235913489649876 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A18 mock treatment 505360.0 82100.0 0.83 414900.0 8430.0 0.09 0.2535 0.2759 442560.0 -4670.95238095202 -0.0433818645715476 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A19 mock treatment 408160.0 -15100.0 -0.15 375840.0 -30600.0 -0.32 -0.3073 -0.6869 458920.0 11689.047619048 0.108563016580477 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A20 mock treatment 455950.0 32700.0 0.33 408880.0 2410.0 0.03 -0.1618 -0.2689 421200.0 -26030.952380952 -0.241764667836048 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A21 mock treatment 426190.0 2910.0 0.03 435120.0 28700.0 0.3 -0.3503 -0.3858 357460.0 -89770.952380952 -0.833755298925903 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A22 mock treatment 378660.0 -44600.0 -0.45 404020.0 -2450.0 -0.03 -0.5786 -0.5202 342600.0 -104630.952380952 -0.971768803444184 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A23 mock treatment 422400.0 -884.0 -0.01 442470.0 36000.0 0.38 0.0116 0.0228 410500.0 -36730.952380952 -0.341141821156749 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base A24 mock treatment 429960.0 6680.0 0.07 463960.0 57500.0 0.6 -0.2162 -0.2171 397450.0 -49780.952380952 -0.462344797870313 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B01 mock treatment 444610.0 21300.0 0.22 423640.0 17200.0 0.18 0.9131 0.8512 541160.0 93929.047619048 0.872373959486495 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B02 mock treatment 494880.0 71600.0 0.73 525380.0 119000.0 1.25 1.1863 0.7277 522370.0 75139.047619048 0.697860248187807 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B03 mock treatment 556830.0 134000.0 1.36 410110.0 3640.0 0.04 0.312 0.2082 430420.0 -16810.952380952 -0.156133139460641 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B04 mock treatment 545500.0 122000.0 1.24 437970.0 31500.0 0.33 0.3369 0.2268 369350.0 -77880.952380952 -0.723325920142433 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B05 mock treatment 413310.0 -9970.0 -0.1 438240.0 31800.0 0.33 0.3114 0.1831 593290.0 146059.047619048 1.35653573543118 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B06 mock treatment 493510.0 70200.0 0.71 459860.0 53400.0 0.56 0.5147 0.5085 465770.0 18539.047619048 0.17218296987457 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B07 mock treatment 405600.0 -17700.0 -0.18 448960.0 42500.0 0.45 0.0546 0.0582 499680.0 52449.047619048 0.487124957641387 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B08 mock treatment 411720.0 -11600.0 -0.12 434370.0 27900.0 0.29 0.1216 0.2813 473140.0 25909.047619048 0.240632467068361 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B09 mock treatment 461500.0 38200.0 0.39 528810.0 122000.0 1.28 0.7275 0.5377 426750.0 -20480.952380952 -0.190218574291199 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B10 mock treatment 387370.0 -35900.0 -0.36 435930.0 29500.0 0.31 -0.2951 -0.4212 392100.0 -55130.952380952 -0.512033374530663 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B11 mock treatment 519940.0 96700.0 0.98 435960.0 29500.0 0.31 0.0758 0.0543 348690.0 -98540.952380952 -0.915207414311187 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B12 mock treatment 407740.0 -15500.0 -0.16 427720.0 21300.0 0.22 -0.1476 -0.3278 447040.0 -190.952380952018 -0.00177348635876836 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B13 mock treatment 447110.0 23800.0 0.24 323200.0 -83300.0 -0.87 -0.2644 -0.283 436030.0 -11200.952380952 -0.104029790850442 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B14 mock treatment 401290.0 -22000.0 -0.22 518740.0 112000.0 1.18 0.7578 0.594 491880.0 44649.047619048 0.414681799145924 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B15 mock treatment 471240.0 48000.0 0.49 388800.0 -17700.0 -0.19 -0.0783 -0.0829 477220.0 29989.047619048 0.278525811512142 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B16 mock treatment 454840.0 31600.0 0.32 421090.0 14600.0 0.15 0.006 0.0113 405650.0 -41580.952380952 -0.386186605605851 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B17 mock treatment 397210.0 -26100.0 -0.26 362930.0 -43500.0 -0.46 -0.5403 -0.8295 449600.0 2369.04761904798 0.0220027297628198 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B18 mock treatment 368430.0 -54900.0 -0.56 427300.0 20800.0 0.22 -0.1946 -0.2933 466180.0 18949.047619048 0.175990879487793 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B19 mock treatment 421800.0 -1480.0 -0.02 388800.0 -17700.0 -0.19 -0.1924 -0.5606 456890.0 9659.04761904798 0.0897092202028109 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B20 mock treatment 376650.0 -46600.0 -0.47 429780.0 23300.0 0.24 0.0626 0.1055 471520.0 24289.047619048 0.225586580303918 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B21 mock treatment 434600.0 11300.0 0.11 409840.0 3370.0 0.04 0.0424 0.1269 467140.0 19909.047619048 0.184906960533388 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B22 mock treatment 462730.0 39400.0 0.4 439490.0 33000.0 0.35 0.7325 0.7545 437490.0 -9740.95238095202 -0.090469917593599 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B23 mock treatment 458040.0 34800.0 0.35 374350.0 -32100.0 -0.34 0.2705 0.4387 480690.0 33459.047619048 0.310753729458201 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base B24 mock treatment 405030.0 -18300.0 -0.19 397470.0 -9000.0 -0.09 -0.2747 -0.7466 414750.0 -32480.952380952 -0.301669587361144 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C01 mock treatment 435890.0 12600.0 0.13 424050.0 17600.0 0.18 0.0679 0.1329 471380.0 24149.047619048 0.224286318484769 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C02 mock treatment 370740.0 -52500.0 -0.53 402630.0 -3840.0 -0.04 -0.781 -0.8433 416000.0 -31230.952380952 -0.290060106833024 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C03 mock treatment 458350.0 35100.0 0.36 341080.0 -65400.0 -0.69 -0.8215 -0.6769 367880.0 -79350.952380952 -0.736978669243501 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C04 mock treatment 436710.0 13400.0 0.14 361450.0 -45000.0 -0.47 -0.6775 -0.7684 382610.0 -64620.952380952 -0.600172550700144 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C05 mock treatment 364890.0 -58400.0 -0.59 369680.0 -36800.0 -0.39 -1.3363 -0.9552 344750.0 -102480.952380952 -0.951800496935819 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C06 mock treatment 397930.0 -25400.0 -0.26 421680.0 15200.0 0.16 -0.7855 -0.6354 413120.0 -34110.952380952 -0.316808349969811 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C07 mock treatment 400190.0 -23100.0 -0.23 367540.0 -38900.0 -0.41 -1.0819 -0.9077 380990.0 -66240.952380952 -0.615218437464587 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C08 mock treatment 325820.0 -97500.0 -0.99 320210.0 -86300.0 -0.9 -1.637 -0.9802 388080.0 -59150.952380952 -0.549369463909095 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C09 mock treatment 326370.0 -96900.0 -0.98 396180.0 -10300.0 -0.11 -1.0396 -0.8558 387600.0 -59630.952380952 -0.553827504431893 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C10 mock treatment 434080.0 10800.0 0.11 315470.0 -91000.0 -0.95 -0.7254 -0.5873 365180.0 -82050.952380952 -0.762055147184239 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C11 mock treatment 412120.0 -11200.0 -0.11 391630.0 -14800.0 -0.16 -0.3023 -0.9891 428810.0 -18420.952380952 -0.171086150380859 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C12 mock treatment 411640.0 -11600.0 -0.12 391800.0 -14700.0 -0.15 -0.2928 -0.986 433200.0 -14030.952380952 -0.130313654766104 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C13 mock treatment 472290.0 49000.0 0.5 405440.0 -1030.0 -0.01 0.1006 0.1665 452800.0 5569.04761904798 0.0517229999148049 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C14 mock treatment 374960.0 -48300.0 -0.49 368960.0 -37500.0 -0.39 -1.0555 -0.9846 383430.0 -63800.952380952 -0.592556731473698 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C15 mock treatment 438080.0 14800.0 0.15 312480.0 -94000.0 -0.98 -0.6655 -0.629 415950.0 -31280.952380952 -0.290524486054149 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C16 mock treatment 389700.0 -33600.0 -0.34 304670.0 -102000.0 -1.07 -1.2736 -0.8974 360500.0 -86730.952380952 -0.805521042281517 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C17 mock treatment 412590.0 -10700.0 -0.11 320770.0 -85700.0 -0.9 -0.9883 -0.83 422400.0 -24830.952380952 -0.230619566529054 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C18 mock treatment 452160.0 28900.0 0.29 332800.0 -73700.0 -0.77 -0.377 -0.4278 414240.0 -32990.952380952 -0.306406255416616 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C19 mock treatment 442180.0 18900.0 0.19 334560.0 -71900.0 -0.75 -0.34 -0.326 493410.0 46179.047619048 0.428891803312341 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C20 mock treatment 431390.0 8110.0 0.08 407360.0 890.0 0.01 -0.6007 -0.6521 371850.0 -75380.952380952 -0.700106959086194 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C21 mock treatment 357960.0 -65300.0 -0.66 326560.0 -79900.0 -0.84 -0.8344 -0.7427 413330.0 -33900.952380952 -0.314857957241087 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C22 mock treatment 396990.0 -26300.0 -0.27 285060.0 -121000.0 -1.27 -1.1773 -0.8279 404500.0 -42730.952380952 -0.396867327691721 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C23 mock treatment 351840.0 -71400.0 -0.73 359860.0 -46600.0 -0.49 -0.9851 -0.8767 371550.0 -75680.952380952 -0.702893234412943 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base C24 mock treatment 395580.0 -27700.0 -0.28 322400.0 -84100.0 -0.88 -1.0892 -0.9059 371760.0 -75470.952380952 -0.700942841684219 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D01 mock treatment 453030.0 29700.0 0.3 457240.0 50800.0 0.53 0.3498 0.5622 435290.0 -11940.952380952 -0.110902603323089 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D02 mock treatment 410240.0 -13000.0 -0.13 532160.0 126000.0 1.32 0.7489 0.5397 490950.0 43719.047619048 0.406044345633003 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D03 mock treatment 467530.0 44200.0 0.45 427930.0 21500.0 0.22 0.3147 0.3408 385890.0 -61340.952380952 -0.56970927379436 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D04 mock treatment 395520.0 -27800.0 -0.28 345230.0 -61200.0 -0.64 -0.8946 -0.9171 378340.0 -68890.952380952 -0.6398305361842 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D05 mock treatment 455730.0 32400.0 0.33 456110.0 49600.0 0.52 0.0627 0.0747 427370.0 -19860.952380952 -0.184460271949252 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D06 mock treatment 464270.0 41000.0 0.42 404800.0 -1670.0 -0.02 0.1891 0.4229 433830.0 -13400.952380952 -0.124462476579932 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D07 mock treatment 409200.0 -14100.0 -0.14 358180.0 -48300.0 -0.51 -0.5367 -0.878 417950.0 -29280.952380952 -0.271949317209158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D08 mock treatment 405090.0 -18200.0 -0.18 472980.0 66500.0 0.7 0.0591 0.0681 456170.0 8939.04761904798 0.0830221594186143 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D09 mock treatment 465250.0 42000.0 0.43 353360.0 -53100.0 -0.56 0.0228 0.0319 462080.0 14849.047619048 0.137911783355562 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D10 mock treatment 340700.0 -82600.0 -0.84 344220.0 -62200.0 -0.65 -1.0261 -0.8135 375070.0 -72160.952380952 -0.670200937245759 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D11 mock treatment 399800.0 -23500.0 -0.24 374930.0 -31500.0 -0.33 -0.617 -0.8841 387380.0 -59850.952380952 -0.555870773004842 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D12 mock treatment 388130.0 -35200.0 -0.36 318600.0 -87900.0 -0.92 -0.4935 -0.455 432530.0 -14700.952380952 -0.136536336329176 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D13 mock treatment 375160.0 -48100.0 -0.49 401720.0 -4750.0 -0.05 -0.4937 -0.8416 419740.0 -27490.952380952 -0.255324541092892 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D14 mock treatment 506770.0 83500.0 0.85 344810.0 -61700.0 -0.65 -0.5016 -0.3648 394720.0 -52510.952380952 -0.487699903343726 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D15 mock treatment 447040.0 23800.0 0.24 451740.0 45300.0 0.47 0.2204 0.2095 499910.0 52679.047619048 0.489261102058561 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D16 mock treatment 395900.0 -27400.0 -0.28 409460.0 2990.0 0.03 -0.3283 -0.54 459840.0 12609.047619048 0.117107594249172 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D17 mock treatment 487150.0 63900.0 0.65 366990.0 -39500.0 -0.41 -0.0469 -0.0583 429200.0 -18030.952380952 -0.167463992456086 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D18 mock treatment 435300.0 12000.0 0.12 347360.0 -59100.0 -0.62 -0.2344 -0.368 442480.0 -4750.95238095202 -0.0441248713253472 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D19 mock treatment 417760.0 -5520.0 -0.06 424000.0 17500.0 0.18 -0.1634 -0.4343 425630.0 -21600.952380952 -0.200620668844394 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D20 mock treatment 424090.0 806.0 0.01 358880.0 -47600.0 -0.5 -0.1903 -0.267 414800.0 -32430.952380952 -0.301205208140019 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D21 mock treatment 407040.0 -16200.0 -0.17 358400.0 -48100.0 -0.5 -0.0962 -0.1503 482310.0 35079.047619048 0.325799616222643 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D22 mock treatment 438030.0 14700.0 0.15 382360.0 -24100.0 -0.25 -0.3613 -0.6383 398250.0 -48980.952380952 -0.454914730332317 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D23 mock treatment 382950.0 -40300.0 -0.41 437040.0 30600.0 0.32 -0.0767 -0.1369 428320.0 -18910.952380952 -0.175637066747881 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base D24 mock treatment 412850.0 -10400.0 -0.11 322510.0 -84000.0 -0.88 -0.754 -0.7759 430590.0 -16640.952380952 -0.154554250108817 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E01 mock treatment 477070.0 53800.0 0.55 461120.0 54700.0 0.57 0.2629 0.2577 378170.0 -69060.952380952 -0.641409425536024 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E02 mock treatment 412270.0 -11000.0 -0.11 408120.0 1650.0 0.02 -0.1125 -0.2865 412480.0 -34750.952380952 -0.322752404000208 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E03 mock treatment 365340.0 -57900.0 -0.59 346880.0 -59600.0 -0.62 -0.8077 -0.8425 449860.0 2629.04761904798 0.0244175017126686 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E04 mock treatment 373170.0 -50100.0 -0.51 350660.0 -55800.0 -0.58 -0.8115 -0.8129 457220.0 9989.04761904798 0.0927741230622344 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E05 mock treatment 378360.0 -44900.0 -0.46 386430.0 -20000.0 -0.21 -0.1448 -0.2052 499330.0 52099.047619048 0.483874303093514 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E06 mock treatment 403610.0 -19700.0 -0.2 326780.0 -79700.0 -0.83 -0.7945 -0.7503 453960.0 6729.04761904798 0.0624965978448995 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E07 mock treatment 468480.0 45200.0 0.46 416080.0 9610.0 0.1 0.0833 0.1135 463300.0 16069.047619048 0.149242636351006 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E08 mock treatment 367840.0 -55400.0 -0.56 362360.0 -44100.0 -0.46 -0.4096 -0.4673 493730.0 46499.047619048 0.43186383032754 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E09 mock treatment 319360.0 -104000.0 -1.06 404960.0 -1510.0 -0.02 -0.3643 -0.3212 491170.0 43939.047619048 0.408087614205952 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E10 mock treatment 498950.0 75700.0 0.77 437560.0 31100.0 0.33 0.4407 0.4235 389890.0 -57340.952380952 -0.532558936104378 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E11 mock treatment 372520.0 -50800.0 -0.52 388580.0 -17900.0 -0.19 -0.5509 -0.8606 438780.0 -8450.95238095202 -0.07848893368858 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E12 mock treatment 398030.0 -25300.0 -0.26 451490.0 45000.0 0.47 0.3136 0.4986 458030.0 10799.047619048 0.100297066444456 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E13 mock treatment 416890.0 -6390.0 -0.06 449470.0 43000.0 0.45 0.3625 0.7039 467040.0 19809.047619048 0.183978202091139 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E14 mock treatment 400000.0 -23300.0 -0.24 406340.0 -130.0 0.0 -0.0631 -0.1873 470490.0 23259.047619048 0.216020368348748 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E15 mock treatment 401150.0 -22100.0 -0.22 403580.0 -2890.0 -0.03 -0.0575 -0.1484 432130.0 -15100.952380952 -0.140251370098174 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E16 mock treatment 457840.0 34600.0 0.35 416960.0 10500.0 0.11 0.2204 0.597 448160.0 929.047619047982 0.00862860819442644 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E17 mock treatment 430100.0 6820.0 0.07 403400.0 -3070.0 -0.03 -0.3263 -0.6205 423900.0 -23330.952380952 -0.216688189895311 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E18 mock treatment 332280.0 -91000.0 -0.92 353550.0 -52900.0 -0.55 -0.5156 -0.4533 484760.0 37529.047619048 0.348554198057757 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E19 mock treatment 445600.0 22300.0 0.23 422170.0 15700.0 0.16 0.3485 0.924 473620.0 26389.047619048 0.245090507591158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E20 mock treatment 442400.0 19100.0 0.19 378110.0 -28400.0 -0.3 0.2736 0.3938 453210.0 5979.04761904798 0.055530909528028 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E21 mock treatment 484020.0 60700.0 0.62 451110.0 44600.0 0.47 0.7474 0.8782 484650.0 37419.047619048 0.347532563771282 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E22 mock treatment 446880.0 23600.0 0.24 420480.0 14000.0 0.15 0.0291 0.0799 429780.0 -17450.952380952 -0.162077193491038 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E23 mock treatment 416050.0 -7230.0 -0.07 386110.0 -20400.0 -0.21 -0.1465 -0.486 431680.0 -15550.952380952 -0.144430783088297 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base E24 mock treatment 412270.0 -11000.0 -0.11 377770.0 -28700.0 -0.3 -0.3051 -0.5615 404960.0 -42270.952380952 -0.392595038857373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F01 mock treatment 421830.0 -1450.0 -0.01 492000.0 85500.0 0.9 0.7918 0.7699 478330.0 31099.047619048 0.288835030221111 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F02 mock treatment 460520.0 37200.0 0.38 433180.0 26700.0 0.28 0.3969 0.7548 470830.0 23599.047619048 0.219178147052396 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F03 mock treatment 452540.0 29300.0 0.3 464710.0 58200.0 0.61 0.2902 0.3369 465920.0 18689.047619048 0.173576107537944 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F04 mock treatment 429340.0 6060.0 0.06 324560.0 -81900.0 -0.86 -0.5452 -0.6156 428870.0 -18360.952380952 -0.170528895315509 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F05 mock treatment 287650.0 -136000.0 -1.38 393250.0 -13200.0 -0.14 -1.0304 -0.7067 399520.0 -47710.952380952 -0.443119498115748 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F06 mock treatment 352000.0 -71300.0 -0.72 503480.0 97000.0 1.02 -0.0032 -0.0025 420690.0 -26540.952380952 -0.246501335891521 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F07 mock treatment 382040.0 -41200.0 -0.42 413760.0 7290.0 0.08 -0.2547 -0.4895 417370.0 -29860.952380952 -0.277336116174206 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F08 mock treatment 433240.0 9960.0 0.1 524840.0 118000.0 1.24 0.4248 0.3214 441930.0 -5300.95238095202 -0.0492330427577196 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F09 mock treatment 324110.0 -99200.0 -1.01 356350.0 -50100.0 -0.53 -0.3685 -0.2902 494780.0 47549.047619048 0.44161579397116 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F10 mock treatment 449920.0 26600.0 0.27 379610.0 -26900.0 -0.28 -0.1215 -0.2816 428430.0 -18800.952380952 -0.174615432461407 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F11 mock treatment 448640.0 25400.0 0.26 371800.0 -34700.0 -0.36 -0.9517 -0.6591 390040.0 -57190.952380952 -0.531165798441004 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F12 mock treatment 448810.0 25500.0 0.26 350770.0 -55700.0 -0.58 -0.0574 -0.0599 405280.0 -41950.952380952 -0.389623011842175 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F13 mock treatment 459150.0 35900.0 0.36 427640.0 21200.0 0.22 0.4671 0.9171 475840.0 28609.047619048 0.265708945009098 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F14 mock treatment 296320.0 -127000.0 -1.29 412210.0 5740.0 0.06 -0.0852 -0.0535 461920.0 14689.047619048 0.136425769847963 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F15 mock treatment 410910.0 -12400.0 -0.13 371230.0 -35200.0 -0.37 -0.2928 -0.7337 446560.0 -670.952380952018 -0.00623152688156613 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F16 mock treatment 437520.0 14200.0 0.14 407950.0 1480.0 0.02 0.0895 0.5609 443360.0 -3870.95238095202 -0.0359517970335513 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F17 mock treatment 335070.0 -88200.0 -0.9 435400.0 28900.0 0.3 -0.3097 -0.2737 493060.0 45829.047619048 0.425641148764468 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F18 mock treatment 485780.0 62500.0 0.64 431680.0 25200.0 0.26 1.0607 0.9496 500320.0 53089.047619048 0.493069011671784 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F19 mock treatment 499200.0 75900.0 0.77 364000.0 -42500.0 -0.44 -0.0087 -0.0093 417450.0 -29780.952380952 -0.276593109420406 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F20 mock treatment 419200.0 -4080.0 -0.04 386910.0 -19600.0 -0.2 -0.1438 -0.6058 453280.0 6049.04761904798 0.0561810404376027 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F21 mock treatment 397230.0 -26100.0 -0.26 363360.0 -43100.0 -0.45 -0.0988 -0.136 448800.0 1569.04761904798 0.0145726622248235 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F22 mock treatment 375470.0 -47800.0 -0.49 379770.0 -26700.0 -0.28 -0.7996 -0.9826 403900.0 -43330.952380952 -0.402439878345218 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F23 mock treatment 385950.0 -37300.0 -0.38 417370.0 10900.0 0.11 -0.2032 -0.4777 430610.0 -16620.952380952 -0.154368498420367 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base F24 mock treatment 395140.0 -28100.0 -0.29 341150.0 -65300.0 -0.68 -0.5914 -0.7261 458720.0 11489.047619048 0.106705499695977 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G01 mock treatment 506660.0 83400.0 0.85 474480.0 68000.0 0.71 0.8041 0.6919 423060.0 -24170.952380952 -0.224489760810207 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G02 mock treatment 463840.0 40600.0 0.41 394660.0 -11800.0 -0.12 0.0337 0.0732 439160.0 -8070.95238095202 -0.0749596516080318 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G03 mock treatment 449810.0 26500.0 0.27 413490.0 7020.0 0.07 -0.2216 -0.3505 396390.0 -50840.952380952 -0.472189637358158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G04 mock treatment 375230.0 -48100.0 -0.49 533020.0 127000.0 1.33 -0.3473 -0.1939 349840.0 -97390.952380952 -0.904526692225317 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G05 mock treatment 428010.0 4730.0 0.05 342210.0 -64300.0 -0.67 -0.7597 -0.7952 417330.0 -29900.952380952 -0.277707619551106 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G06 mock treatment 481310.0 58000.0 0.59 400960.0 -5510.0 -0.06 -0.2774 -0.2791 372430.0 -74800.952380952 -0.694720160121147 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G07 mock treatment 382970.0 -40300.0 -0.41 457060.0 50600.0 0.53 0.191 0.2459 434880.0 -12350.952380952 -0.114710512936312 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G08 mock treatment 355860.0 -67400.0 -0.69 372560.0 -33900.0 -0.36 -0.2552 -0.2173 414720.0 -32510.952380952 -0.301948214893818 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G09 mock treatment 512590.0 89300.0 0.91 357960.0 -48500.0 -0.51 0.3391 0.3201 464830.0 17599.047619048 0.163452640517424 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G10 mock treatment 421940.0 -1340.0 -0.01 342790.0 -63700.0 -0.67 -0.2968 -0.4394 445560.0 -1670.95238095202 -0.0155191113040615 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G11 mock treatment 408390.0 -14900.0 -0.15 457790.0 51300.0 0.54 0.2808 0.4021 487160.0 39929.047619048 0.370844400671745 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G12 mock treatment 500430.0 77100.0 0.78 400770.0 -5700.0 -0.06 0.1811 0.1314 343750.0 -103480.952380952 -0.961088081358314 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G13 mock treatment 370880.0 -52400.0 -0.53 374560.0 -31900.0 -0.33 0.3095 0.2526 530340.0 83109.047619048 0.771882296035095 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G14 mock treatment 416290.0 -6990.0 -0.07 414880.0 8410.0 0.09 -0.0131 -0.0347 417730.0 -29500.952380952 -0.273992585782107 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G15 mock treatment 511240.0 88000.0 0.89 376000.0 -30500.0 -0.32 0.7789 0.6481 481490.0 34259.047619048 0.318183796996197 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G16 mock treatment 472330.0 49000.0 0.5 380670.0 -25800.0 -0.27 0.1682 0.2522 479130.0 31899.047619048 0.296265097759108 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G17 mock treatment 429550.0 6270.0 0.06 448160.0 41700.0 0.44 0.1601 0.2875 461460.0 14229.047619048 0.132153481013615 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G18 mock treatment 486720.0 63400.0 0.64 442400.0 35900.0 0.38 0.8721 0.8569 450680.0 3449.04761904798 0.0320333209391147 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G19 mock treatment 461280.0 38000.0 0.39 435550.0 29100.0 0.3 1.0096 0.9414 506490.0 59259.047619048 0.550373407558581 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G20 mock treatment 449920.0 26600.0 0.27 424890.0 18400.0 0.19 0.3121 0.7866 469920.0 22689.047619048 0.210726445227925 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G21 mock treatment 434270.0 11000.0 0.11 406350.0 -120.0 0.0 0.242 0.5786 444170.0 -3060.95238095202 -0.02842885365133 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G22 mock treatment 418790.0 -4490.0 -0.05 335580.0 -70900.0 -0.74 -0.3242 -0.3641 491220.0 43989.047619048 0.408551993427077 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G23 mock treatment 406790.0 -16500.0 -0.17 411520.0 5050.0 0.05 -0.1935 -0.3919 400640.0 -46590.952380952 -0.432717403562553 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base G24 mock treatment 345930.0 -77400.0 -0.79 375360.0 -31100.0 -0.33 -0.8106 -0.8405 440850.0 -6380.95238095202 -0.0592636339340146 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H01 mock treatment 428710.0 5430.0 0.06 456540.0 50100.0 0.52 0.6773 0.8817 497160.0 49929.047619048 0.463720244896699 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H02 mock treatment 364530.0 -58800.0 -0.6 299520.0 -107000.0 -1.12 -0.8326 -0.6502 462430.0 15199.047619048 0.141162437903435 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H03 mock treatment 493600.0 70300.0 0.71 334890.0 -71600.0 -0.75 0.6439 0.459 529090.0 81859.047619048 0.760272815506976 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H04 mock treatment 435110.0 11800.0 0.12 384410.0 -22100.0 -0.23 0.5516 0.6145 514720.0 67489.047619048 0.626810227355718 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H05 mock treatment 427800.0 4520.0 0.05 441060.0 34600.0 0.36 0.8317 0.7414 470590.0 23359.047619048 0.216949126790997 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H06 mock treatment 442460.0 19200.0 0.19 365240.0 -41200.0 -0.43 -0.038 -0.0451 403600.0 -43630.952380952 -0.405226153671967 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H07 mock treatment 506430.0 83100.0 0.84 322140.0 -84300.0 -0.88 0.2531 0.1893 447680.0 449.047619047982 0.00417056767162867 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H08 mock treatment 341570.0 -81700.0 -0.83 413940.0 7470.0 0.08 -0.1637 -0.1736 445650.0 -1580.95238095202 -0.0146832287060369 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H09 mock treatment 382420.0 -40900.0 -0.42 498200.0 91700.0 0.96 0.1529 0.1431 443700.0 -3530.95238095202 -0.0327940183299029 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H10 mock treatment 433550.0 10300.0 0.1 417840.0 11400.0 0.12 0.0264 0.1094 427700.0 -19530.952380952 -0.181395369089829 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H11 mock treatment 479520.0 56200.0 0.57 353500.0 -53000.0 -0.55 -0.3252 -0.3139 446740.0 -490.952380952018 -0.00455976168551697 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H12 mock treatment 496410.0 73100.0 0.74 466800.0 60300.0 0.63 1.0424 0.9439 495070.0 47839.047619048 0.444309193453684 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H13 mock treatment 372100.0 -51200.0 -0.52 471200.0 64700.0 0.68 0.4789 0.4157 530330.0 83099.047619048 0.77178942019087 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H14 mock treatment 393850.0 -29400.0 -0.3 388870.0 -17600.0 -0.18 0.0113 0.022 482480.0 35249.047619048 0.327378505574467 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H15 mock treatment 450920.0 27600.0 0.28 400960.0 -5510.0 -0.06 0.5886 0.7779 484320.0 37089.047619048 0.344467660911859 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H16 mock treatment 421460.0 -1820.0 -0.02 385820.0 -20600.0 -0.22 -0.1924 -0.7219 447720.0 489.047619047982 0.00454207104852848 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H17 mock treatment 443210.0 19900.0 0.2 406270.0 -200.0 0.0 0.2461 0.3173 517760.0 70529.047619048 0.655044484000104 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H18 mock treatment 496710.0 73400.0 0.75 425830.0 19400.0 0.2 0.9025 0.9042 506920.0 59689.047619048 0.554367068860254 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H19 mock treatment 471550.0 48300.0 0.49 462510.0 56000.0 0.59 0.8627 0.9674 483080.0 35849.047619048 0.332951056227964 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H20 mock treatment 492800.0 69500.0 0.71 466910.0 60400.0 0.63 0.9367 0.9125 467930.0 20699.047619048 0.19224415222716 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H21 mock treatment 392920.0 -30400.0 -0.31 412890.0 6420.0 0.07 0.1003 0.1585 436680.0 -10550.952380952 -0.0979928609758203 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H22 mock treatment 393070.0 -30200.0 -0.31 420230.0 13800.0 0.14 -0.0854 -0.2467 452070.0 4839.04761904798 0.0449430632863833 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H23 mock treatment 502600.0 79300.0 0.81 344390.0 -62100.0 -0.65 0.4005 0.2797 415200.0 -32030.952380952 -0.297490174371021 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base H24 mock treatment 380000.0 -43300.0 -0.44 404510.0 -1960.0 -0.02 -0.289 -0.6148 430080.0 -17150.952380952 -0.15929091816429 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I01 mock treatment 440980.0 17700.0 0.18 347890.0 -58600.0 -0.61 -0.0245 -0.0336 450970.0 3739.04761904798 0.0347267204216384 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I02 mock treatment 468800.0 45500.0 0.46 537080.0 131000.0 1.37 0.6029 0.3226 329850.0 -117380.952380952 -1.090185504831 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I03 mock treatment 345780.0 -77500.0 -0.79 382570.0 -23900.0 -0.25 -0.7522 -0.6165 358560.0 -88670.952380952 -0.823538956061158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I04 mock treatment 481610.0 58300.0 0.59 433150.0 26700.0 0.28 0.3237 0.4505 454020.0 6789.04761904798 0.0630538529102492 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I05 mock treatment 365440.0 -57800.0 -0.59 275530.0 -131000.0 -1.37 -0.8549 -0.558 438030.0 -9200.95238095202 -0.0854546220054516 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I06 mock treatment 327130.0 -96200.0 -0.98 399010.0 -7460.0 -0.08 -0.528 -0.5262 463550.0 16319.047619048 0.15156453245663 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I07 mock treatment 430510.0 7230.0 0.07 476260.0 69800.0 0.73 0.3412 0.4344 420580.0 -26650.952380952 -0.247522970177996 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I08 mock treatment 416120.0 -7160.0 -0.07 443070.0 36600.0 0.38 0.5558 0.7886 502050.0 54819.047619048 0.509136532722701 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I09 mock treatment 467560.0 44300.0 0.45 386310.0 -20200.0 -0.21 -0.0103 -0.018 450200.0 2969.04761904798 0.027575280416317 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I10 mock treatment 422980.0 -304.0 0.0 459290.0 52800.0 0.55 1.001 0.8512 513850.0 66619.047619048 0.618730028908147 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I11 mock treatment 452720.0 29400.0 0.3 404690.0 -1780.0 -0.02 0.6768 0.6353 557160.0 109929.047619048 1.02097531024642 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I12 mock treatment 393280.0 -30000.0 -0.3 398030.0 -8440.0 -0.09 -0.5206 -0.786 385120.0 -62110.952380952 -0.576860713799681 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I13 mock treatment 465570.0 42300.0 0.43 309060.0 -97400.0 -1.02 -0.4413 -0.3508 474160.0 26929.047619048 0.250105803179306 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I14 mock treatment 425950.0 2670.0 0.03 445840.0 39400.0 0.41 0.4737 0.7994 457320.0 10089.047619048 0.0937028815044839 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I15 mock treatment 422660.0 -624.0 -0.01 459430.0 53000.0 0.55 0.4201 0.6429 441870.0 -5360.95238095202 -0.0497902978230694 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I16 mock treatment 398080.0 -25200.0 -0.26 427680.0 21200.0 0.22 0.3093 0.5113 497200.0 49969.047619048 0.464091748273599 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I17 mock treatment 466120.0 42800.0 0.44 519210.0 113000.0 1.18 1.0099 0.768 488040.0 40809.047619048 0.379017474963541 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I18 mock treatment 436660.0 13400.0 0.14 481930.0 75500.0 0.79 0.9586 0.891 488960.0 41729.047619048 0.387562052632237 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I19 mock treatment 473250.0 50000.0 0.51 441520.0 35100.0 0.37 0.7566 0.8262 519070.0 71839.047619048 0.667211219593572 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I20 mock treatment 433600.0 10300.0 0.1 366560.0 -39900.0 -0.42 0.112 0.1886 487570.0 40339.047619048 0.374652310284969 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I21 mock treatment 454950.0 31700.0 0.32 372000.0 -34500.0 -0.36 0.0379 0.0763 459420.0 12189.047619048 0.113206808791724 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I22 mock treatment 398460.0 -24800.0 -0.25 393540.0 -12900.0 -0.14 -0.0624 -0.1352 437700.0 -9530.95238095202 -0.088519524864875 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I23 mock treatment 334240.0 -89000.0 -0.9 364030.0 -42400.0 -0.44 -0.8092 -0.6737 385200.0 -62030.952380952 -0.576117707045881 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base I24 mock treatment 356510.0 -66800.0 -0.68 320720.0 -85700.0 -0.9 -1.4253 -0.9827 390680.0 -56550.952380952 -0.525221744410607 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J01 mock treatment 430980.0 7700.0 0.08 370810.0 -35700.0 -0.37 -0.0077 -0.0179 462720.0 15489.047619048 0.143855837385959 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J02 mock treatment 399610.0 -23700.0 -0.24 405280.0 -1190.0 -0.01 0.1982 0.3348 460450.0 13219.047619048 0.122773020746894 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J03 mock treatment 401880.0 -21400.0 -0.22 473520.0 67100.0 0.7 0.4363 0.5072 494930.0 47699.047619048 0.443008931634534 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J04 mock treatment 344060.0 -79200.0 -0.81 300640.0 -106000.0 -1.11 -0.505 -0.325 468680.0 21449.047619048 0.199209840544031 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J05 mock treatment 314200.0 -109000.0 -1.11 304730.0 -102000.0 -1.07 -1.0108 -0.5694 522460.0 75229.047619048 0.698696130785832 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J06 mock treatment 420980.0 -2300.0 -0.02 347480.0 -59000.0 -0.62 -1.1479 -0.8673 356030.0 -91200.952380952 -0.847036544650071 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J07 mock treatment 312200.0 -111000.0 -1.13 365920.0 -40500.0 -0.42 -1.118 -0.7992 450030.0 2799.04761904798 0.0259963910644928 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J08 mock treatment 334910.0 -88400.0 -0.9 399380.0 -7090.0 -0.07 -0.2614 -0.269 457920.0 10689.047619048 0.0992754321579812 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J09 mock treatment 487270.0 64000.0 0.65 414410.0 7940.0 0.08 0.6818 0.8252 463400.0 16169.047619048 0.150171394793256 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J10 mock treatment 352980.0 -70300.0 -0.71 419290.0 12800.0 0.13 -0.2384 -0.2465 404520.0 -42710.952380952 -0.396681576003271 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J11 mock treatment 392960.0 -30300.0 -0.31 314960.0 -91500.0 -0.96 -1.0237 -0.8905 401370.0 -45860.952380952 -0.425937466934131 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J12 mock treatment 392580.0 -30700.0 -0.31 468960.0 62500.0 0.65 0.3785 0.248 569280.0 122049.047619048 1.13354083344706 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J13 mock treatment 441170.0 17900.0 0.18 396500.0 -9970.0 -0.1 0.8178 0.6747 566080.0 118849.047619048 1.10382056329508 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J14 mock treatment 391700.0 -31600.0 -0.32 403360.0 -3110.0 -0.03 -0.271 -0.3925 391720.0 -55510.952380952 -0.515562656611212 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J15 mock treatment 434770.0 11500.0 0.12 428120.0 21700.0 0.23 1.1391 0.7884 521770.0 74539.047619048 0.69228769753431 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J16 mock treatment 451250.0 28000.0 0.28 414360.0 7890.0 0.08 0.3922 0.6722 438720.0 -8510.95238095202 -0.0790461887539298 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J17 mock treatment 442150.0 18900.0 0.19 411610.0 5140.0 0.05 0.1672 0.228 398500.0 -48730.952380952 -0.452592834226693 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J18 mock treatment 438970.0 15700.0 0.16 406690.0 220.0 0.0 0.6043 0.7334 528320.0 81089.047619048 0.753121375501654 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J19 mock treatment 419610.0 -3670.0 -0.04 443410.0 36900.0 0.39 0.7202 0.8207 494140.0 46909.047619048 0.435671739940763 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J20 mock treatment 451460.0 28200.0 0.29 409020.0 2550.0 0.03 0.2382 0.7038 445670.0 -1560.95238095202 -0.014497477017587 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J21 mock treatment 432490.0 9210.0 0.09 424040.0 17600.0 0.18 0.4249 0.5613 431930.0 -15300.952380952 -0.142108886982673 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J22 mock treatment 355490.0 -67800.0 -0.69 376810.0 -29700.0 -0.31 -0.744 -0.8942 424200.0 -23030.952380952 -0.213901914568562 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J23 mock treatment 404190.0 -19100.0 -0.19 399230.0 -7240.0 -0.08 -0.5707 -0.7201 365850.0 -81380.952380952 -0.755832465621167 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base J24 mock treatment 362290.0 -61000.0 -0.62 370160.0 -36300.0 -0.38 -0.2393 -0.2933 477630.0 30399.047619048 0.282333721125365 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K01 mock treatment 393970.0 -29300.0 -0.3 450600.0 44100.0 0.46 0.6123 0.5733 464290.0 17059.047619048 0.158437344929277 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K02 mock treatment 403770.0 -19500.0 -0.2 432960.0 26500.0 0.28 0.5292 0.4892 442240.0 -4990.95238095202 -0.0463538915867461 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K03 mock treatment 348340.0 -74900.0 -0.76 343170.0 -63300.0 -0.66 -1.4592 -0.9973 372500.0 -74730.952380952 -0.694070029211572 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K04 mock treatment 445570.0 22300.0 0.23 445220.0 38800.0 0.41 0.2005 0.2644 478610.0 31379.047619048 0.29143555385941 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K05 mock treatment 292200.0 -131000.0 -1.33 356850.0 -49600.0 -0.52 -0.7658 -0.5121 492920.0 45689.047619048 0.424340886945319 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K06 mock treatment 395360.0 -27900.0 -0.28 396060.0 -10400.0 -0.11 -0.614 -0.9162 409070.0 -38160.952380952 -0.354423066880917 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K07 mock treatment 450510.0 27200.0 0.28 469140.0 62700.0 0.66 0.3611 0.4012 395580.0 -51650.952380952 -0.47971258074038 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K08 mock treatment 380190.0 -43100.0 -0.44 449770.0 43300.0 0.45 0.4965 0.4643 460390.0 13159.047619048 0.122215765681545 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K09 mock treatment 383880.0 -39400.0 -0.4 421330.0 14900.0 0.16 -0.1487 -0.3354 452230.0 4999.04761904798 0.0464290767939826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K10 mock treatment 436510.0 13200.0 0.13 453780.0 47300.0 0.5 0.6989 0.5101 576000.0 128769.047619048 1.19595340076623 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K11 mock treatment 521040.0 97800.0 0.99 430360.0 23900.0 0.25 1.2751 0.9029 494560.0 47329.047619048 0.439572525398211 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K12 mock treatment 490810.0 67500.0 0.69 393610.0 -12900.0 -0.13 1.1799 0.8096 545550.0 98319.047619048 0.913146455101249 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K13 mock treatment 534140.0 111000.0 1.13 507420.0 101000.0 1.06 1.0291 0.6418 408550.0 -38680.952380952 -0.359252610780615 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K14 mock treatment 515060.0 91800.0 0.93 426080.0 19600.0 0.21 0.7107 0.6967 485120.0 37889.047619048 0.351897728449855 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K15 mock treatment 507460.0 84200.0 0.86 419100.0 12600.0 0.13 1.4212 0.8091 606840.0 159609.047619048 1.48238250435599 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K16 mock treatment 412860.0 -10400.0 -0.11 432840.0 26400.0 0.28 1.1571 0.7483 568380.0 121149.047619048 1.12518200746682 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K17 mock treatment 455570.0 32300.0 0.33 412650.0 6180.0 0.06 0.7006 0.7047 547710.0 100479.047619048 0.93320763745384 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K18 mock treatment 529440.0 106000.0 1.08 471520.0 65100.0 0.68 1.8537 0.9854 542740.0 95509.047619048 0.887048342874038 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K19 mock treatment 515840.0 92600.0 0.94 488290.0 81800.0 0.86 1.9088 0.9101 621440.0 174209.047619048 1.61798123692442 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K20 mock treatment 528230.0 105000.0 1.07 442190.0 35700.0 0.37 1.3045 0.9119 532490.0 85259.047619048 0.79185060254346 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K21 mock treatment 515090.0 91800.0 0.93 411310.0 4840.0 0.05 0.5336 0.5697 449570.0 2339.04761904798 0.0217241022301449 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K22 mock treatment 482690.0 59400.0 0.6 444250.0 37800.0 0.4 0.7049 0.8608 449870.0 2639.04761904798 0.0245103775568935 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K23 mock treatment 541810.0 119000.0 1.2 421300.0 14800.0 0.16 1.1612 0.8193 478830.0 31599.047619048 0.293478822432359 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base K24 mock treatment 430740.0 7460.0 0.08 484590.0 78100.0 0.82 0.574 0.6095 428690.0 -18540.952380952 -0.172200660511558 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L01 mock treatment 339680.0 -83600.0 -0.85 451520.0 45100.0 0.47 -0.0381 -0.0347 428000.0 -19230.952380952 -0.17860909376308 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L02 mock treatment 510330.0 87000.0 0.88 372660.0 -33800.0 -0.35 0.3458 0.3385 482560.0 35329.047619048 0.328121512328267 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L03 mock treatment 352410.0 -70900.0 -0.72 361180.0 -45300.0 -0.47 -0.8564 -0.8064 457400.0 10169.047619048 0.0944458882582836 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L04 mock treatment 342750.0 -80500.0 -0.82 311430.0 -95000.0 -1.0 -1.197 -0.8525 387310.0 -59920.952380952 -0.556520903914416 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L05 mock treatment 298610.0 -125000.0 -1.27 448030.0 41600.0 0.44 -0.0954 -0.0674 486430.0 39199.047619048 0.364064464043324 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L06 mock treatment 417520.0 -5760.0 -0.06 371880.0 -34600.0 -0.36 -0.7124 -0.8813 383920.0 -63310.952380952 -0.588005815106675 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L07 mock treatment 438890.0 15600.0 0.16 384810.0 -21700.0 -0.23 -0.1159 -0.2386 409340.0 -37890.952380952 -0.351915419086843 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L08 mock treatment 338830.0 -84500.0 -0.86 352090.0 -54400.0 -0.57 -0.7605 -0.7035 417790.0 -29440.952380952 -0.273435330716758 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L09 mock treatment 450510.0 27200.0 0.28 306570.0 -99900.0 -1.05 -0.4543 -0.4154 430560.0 -16670.952380952 -0.154832877641492 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L10 mock treatment 417490.0 -5790.0 -0.06 394130.0 -12300.0 -0.13 0.4315 0.4279 554570.0 107339.047619048 0.996920466592158 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L11 mock treatment 441010.0 17700.0 0.18 389340.0 -17100.0 -0.18 -0.1974 -0.467 411540.0 -35690.952380952 -0.331482733357354 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L12 mock treatment 455950.0 32700.0 0.33 447950.0 41500.0 0.43 -0.2805 -0.2323 415900.0 -31330.952380952 -0.290988865275274 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L13 mock treatment 417920.0 -5360.0 -0.05 333040.0 -73400.0 -0.77 -0.6849 -0.7622 437050.0 -10180.952380952 -0.094556454739497 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L14 mock treatment 460380.0 37100.0 0.38 397510.0 -8960.0 -0.09 0.8732 0.683 574920.0 127689.047619048 1.18592280958994 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L15 mock treatment 371260.0 -52000.0 -0.53 373220.0 -33200.0 -0.35 -0.98 -0.8837 426420.0 -20810.952380952 -0.193283477150623 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L16 mock treatment 396220.0 -27100.0 -0.28 454370.0 47900.0 0.5 0.3371 0.4154 434720.0 -12510.952380952 -0.116196526443911 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L17 mock treatment 508670.0 85400.0 0.87 431650.0 25200.0 0.26 1.5346 0.8492 608800.0 161569.047619048 1.50058616982408 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L18 mock treatment 420710.0 -2570.0 -0.03 409160.0 2690.0 0.03 -0.1109 -0.5859 442520.0 -4710.95238095202 -0.0437533679484474 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L19 mock treatment 459230.0 35900.0 0.37 493040.0 86600.0 0.91 1.5339 0.9562 538400.0 91169.047619048 0.846740226480408 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L20 mock treatment 431800.0 8520.0 0.09 456520.0 50100.0 0.52 1.0597 0.8753 544680.0 97449.047619048 0.905066256653679 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L21 mock treatment 455040.0 31800.0 0.32 374950.0 -31500.0 -0.33 0.2111 0.3019 502960.0 55729.047619048 0.517588234547172 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L22 mock treatment 444550.0 21300.0 0.22 452560.0 46100.0 0.48 1.0736 0.931 527840.0 80609.047619048 0.748663334978857 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L23 mock treatment 457870.0 34600.0 0.35 506640.0 100000.0 1.05 0.6399 0.5423 410250.0 -36980.952380952 -0.343463717262373 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base L24 mock treatment 395680.0 -27600.0 -0.28 364520.0 -41900.0 -0.44 -0.2258 -0.4046 457280.0 10049.047619048 0.0933313781275841 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M01 mock treatment 373320.0 -50000.0 -0.51 317140.0 -89300.0 -0.94 -0.163 -0.1228 504110.0 56879.047619048 0.528268956633042 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M02 mock treatment 460750.0 37500.0 0.38 429760.0 23300.0 0.24 0.7253 0.6867 434210.0 -13020.952380952 -0.120933194499384 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M03 mock treatment 460920.0 37600.0 0.38 388010.0 -18500.0 -0.19 0.5456 0.7088 499160.0 51929.047619048 0.48229541374169 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M04 mock treatment 417230.0 -6050.0 -0.06 423380.0 16900.0 0.18 0.1101 0.0953 539490.0 92259.047619048 0.856863693500928 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M05 mock treatment 453280.0 30000.0 0.3 460710.0 54200.0 0.57 0.0212 0.0243 406310.0 -40920.952380952 -0.380056799887004 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M06 mock treatment 468660.0 45400.0 0.46 411850.0 5380.0 0.06 0.4356 0.6981 440910.0 -6320.95238095202 -0.0587063788686649 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M07 mock treatment 413820.0 -9460.0 -0.1 397530.0 -8940.0 -0.09 -0.5329 -0.6671 363050.0 -84180.952380952 -0.781837702004154 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M08 mock treatment 385620.0 -37700.0 -0.38 421210.0 14700.0 0.15 0.09 0.1285 432190.0 -15040.952380952 -0.139694115032824 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M09 mock treatment 442580.0 19300.0 0.2 421250.0 14800.0 0.15 0.5087 0.4561 557680.0 110449.047619048 1.02580485414612 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M10 mock treatment 477970.0 54700.0 0.56 449010.0 42500.0 0.45 0.6763 0.8817 476670.0 29439.047619048 0.273417640079769 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M11 mock treatment 514400.0 91100.0 0.93 398240.0 -8230.0 -0.09 0.3377 0.3576 429610.0 -17620.952380952 -0.163656082842862 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M12 mock treatment 409530.0 -13800.0 -0.14 266590.0 -140000.0 -1.47 -1.1471 -0.7288 389630.0 -57600.952380952 -0.534973708054227 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M13 mock treatment 502400.0 79100.0 0.8 459620.0 53200.0 0.56 1.0232 0.7546 422900.0 -24330.952380952 -0.225975774317806 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M14 mock treatment 403360.0 -19900.0 -0.2 454840.0 48400.0 0.51 0.6746 0.6636 470320.0 23089.047619048 0.214441478996924 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M15 mock treatment 467200.0 43900.0 0.45 475090.0 68600.0 0.72 1.6621 0.9152 601630.0 154399.047619048 1.43399418951479 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M16 mock treatment 474680.0 51400.0 0.52 401530.0 -4940.0 -0.05 1.0267 0.817 515230.0 67999.047619048 0.63154689541119 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M17 mock treatment 465920.0 42600.0 0.43 421720.0 15300.0 0.16 0.3814 0.7871 449930.0 2699.04761904798 0.0250676326222432 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M18 mock treatment 473710.0 50400.0 0.51 404960.0 -1510.0 -0.02 0.9247 0.719 467520.0 20289.047619048 0.188436242613937 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M19 mock treatment 455730.0 32400.0 0.33 391970.0 -14500.0 -0.15 0.5678 0.7344 492320.0 45089.047619048 0.418768336291822 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M20 mock treatment 510460.0 87200.0 0.89 448550.0 42100.0 0.44 0.9324 0.874 485220.0 37989.047619048 0.352826486892104 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M21 mock treatment 535730.0 112000.0 1.14 450840.0 44400.0 0.46 1.3423 0.892 535920.0 88689.047619048 0.823707017112619 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M22 mock treatment 424280.0 996.0 0.01 441890.0 35400.0 0.37 0.6977 0.6418 446420.0 -810.952380952018 -0.00753178870071548 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M23 mock treatment 429440.0 6160.0 0.06 364570.0 -41900.0 -0.44 -0.1587 -0.224 408450.0 -38780.952380952 -0.360181369222864 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base M24 mock treatment 410320.0 -13000.0 -0.13 376730.0 -29700.0 -0.31 -0.7371 -0.8585 414760.0 -32470.952380952 -0.301576711516919 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N01 mock treatment 382990.0 -40300.0 -0.41 514340.0 108000.0 1.13 0.7013 0.5146 516200.0 68969.047619048 0.640555852301011 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N02 mock treatment 387360.0 -35900.0 -0.37 468640.0 62200.0 0.65 0.6921 0.6412 511610.0 64379.047619048 0.597925839801757 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N03 mock treatment 380210.0 -43100.0 -0.44 409880.0 3410.0 0.04 -0.4275 -0.6645 396640.0 -50590.952380952 -0.469867741252535 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N04 mock treatment 365620.0 -57700.0 -0.59 381950.0 -24500.0 -0.26 -0.7535 -0.9136 394400.0 -52830.952380952 -0.490671930358924 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N05 mock treatment 413560.0 -9720.0 -0.1 350740.0 -55700.0 -0.58 -0.5075 -0.5852 384540.0 -62690.952380952 -0.582247512764728 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N06 mock treatment 292190.0 -131000.0 -1.33 359250.0 -47200.0 -0.49 -0.6758 -0.4146 527970.0 80739.047619048 0.749870720953781 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N07 mock treatment 353500.0 -69800.0 -0.71 406100.0 -370.0 0.0 -0.6058 -0.5053 488930.0 41699.047619048 0.387283425099562 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N08 mock treatment 356860.0 -66400.0 -0.68 411960.0 5490.0 0.06 0.3103 0.2536 553640.0 106409.047619048 0.988283013079237 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N09 mock treatment 475520.0 52200.0 0.53 389130.0 -17300.0 -0.18 0.5736 0.5101 550690.0 103459.047619048 0.960884639032876 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N10 mock treatment 471790.0 48500.0 0.49 344970.0 -61500.0 -0.64 0.6273 0.4571 559950.0 112719.047619048 1.04688767078518 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N11 mock treatment 323400.0 -99900.0 -1.02 417470.0 11000.0 0.12 0.1002 0.0778 499220.0 51989.047619048 0.482852668807039 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N12 mock treatment 404670.0 -18600.0 -0.19 428520.0 22100.0 0.23 0.135 0.3956 456840.0 9609.04761904798 0.0892448409816862 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N13 mock treatment 523900.0 101000.0 1.02 469280.0 62800.0 0.66 1.0159 0.7135 519280.0 72049.047619048 0.669161612322296 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N14 mock treatment 525240.0 102000.0 1.04 388930.0 -17500.0 -0.18 1.03 0.7598 514720.0 67489.047619048 0.626810227355718 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N15 mock treatment 478000.0 54700.0 0.56 456610.0 50100.0 0.53 1.2898 0.9255 491000.0 43769.047619048 0.406508724854128 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N16 mock treatment 478590.0 55300.0 0.56 494810.0 88300.0 0.93 1.0054 0.8241 443200.0 -4030.95238095202 -0.0374378105411505 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N17 mock treatment 493390.0 70100.0 0.71 451650.0 45200.0 0.47 1.1402 0.9878 509370.0 62139.047619048 0.577121650695367 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N18 mock treatment 452410.0 29100.0 0.3 428870.0 22400.0 0.23 0.8086 0.915 522400.0 75169.047619048 0.698138875720482 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N19 mock treatment 466650.0 43400.0 0.44 422640.0 16200.0 0.17 0.5169 0.7861 443700.0 -3530.95238095202 -0.0327940183299029 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N20 mock treatment 405980.0 -17300.0 -0.18 399550.0 -6920.0 -0.07 0.7423 0.597 547520.0 100289.047619048 0.931442996413565 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N21 mock treatment 469670.0 46400.0 0.47 432570.0 26100.0 0.27 0.8842 0.8211 546650.0 99419.047619048 0.923362797965994 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N22 mock treatment 437230.0 13900.0 0.14 416000.0 9530.0 0.1 0.7589 0.824 520670.0 73439.047619048 0.682071354669565 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N23 mock treatment 355520.0 -67800.0 -0.69 424210.0 17700.0 0.19 -0.0663 -0.0414 574600.0 127369.047619048 1.18295078257474 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base N24 mock treatment 470940.0 47700.0 0.48 363290.0 -43200.0 -0.45 0.0074 0.0108 459860.0 12629.047619048 0.117293345937622 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O01 mock treatment 430760.0 7480.0 0.08 451700.0 45200.0 0.47 0.1506 0.285 423680.0 -23550.952380952 -0.21873145846826 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O02 mock treatment 477390.0 54100.0 0.55 363170.0 -43300.0 -0.45 0.1393 0.0971 362840.0 -84390.952380952 -0.783788094732878 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O03 mock treatment 445120.0 21800.0 0.22 463090.0 56600.0 0.59 0.1451 0.1177 343560.0 -103670.952380952 -0.962852722398588 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O04 mock treatment 450570.0 27300.0 0.28 378410.0 -28100.0 -0.29 0.7607 0.59 487220.0 39989.047619048 0.371401655737095 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O05 mock treatment 310240.0 -113000.0 -1.15 390330.0 -16100.0 -0.17 -1.4145 -0.8962 368640.0 -78590.952380952 -0.729920105082405 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O06 mock treatment 495380.0 72100.0 0.73 529120.0 123000.0 1.29 0.6971 0.398 350670.0 -96560.952380952 -0.896817997154646 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O07 mock treatment 352270.0 -71000.0 -0.72 419110.0 12600.0 0.13 -0.5014 -0.4589 482440.0 35209.047619048 0.327007002197567 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O08 mock treatment 475640.0 52400.0 0.53 481350.0 74900.0 0.78 0.8749 0.8115 501930.0 54699.047619048 0.508022022592002 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O09 mock treatment 440980.0 17700.0 0.18 451780.0 45300.0 0.47 1.2881 0.6696 646880.0 199649.047619048 1.8542573846327 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O10 mock treatment 417320.0 -5960.0 -0.06 349720.0 -56700.0 -0.59 -0.1049 -0.1268 434780.0 -12450.952380952 -0.115639271378561 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O11 mock treatment 370680.0 -52600.0 -0.53 442460.0 36000.0 0.38 -0.4544 -0.4946 434620.0 -12610.952380952 -0.117125284886161 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O12 mock treatment 406240.0 -17000.0 -0.17 416800.0 10300.0 0.11 0.0112 0.0245 482570.0 35339.047619048 0.328214388172492 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O13 mock treatment 489620.0 66300.0 0.67 427850.0 21400.0 0.22 0.2157 0.21 472730.0 25499.047619048 0.236824557455137 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O14 mock treatment 534820.0 112000.0 1.13 424800.0 18300.0 0.19 1.2331 0.5816 629560.0 182329.047619048 1.69339642243508 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O15 mock treatment 480850.0 57600.0 0.58 413640.0 7170.0 0.08 0.22 0.3567 442250.0 -4980.95238095202 -0.0462610157425211 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O16 mock treatment 504870.0 81600.0 0.83 517480.0 111000.0 1.16 1.0621 0.6477 515240.0 68009.047619048 0.631639771255415 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O17 mock treatment 491200.0 67900.0 0.69 431280.0 24800.0 0.26 1.2903 0.9067 564700.0 117469.047619048 1.09100369679204 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O18 mock treatment 421440.0 -1840.0 -0.02 392920.0 -13500.0 -0.14 0.3768 0.5034 523040.0 75809.047619048 0.704082929750879 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O19 mock treatment 515240.0 92000.0 0.93 326410.0 -80100.0 -0.84 0.1226 0.097 447270.0 39.0476190479822 3.62658058405572E-4 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O20 mock treatment 526300.0 103000.0 1.05 443010.0 36500.0 0.38 1.3846 0.9403 532190.0 84959.047619048 0.789064327216711 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O21 mock treatment 451300.0 28000.0 0.28 393700.0 -12800.0 -0.13 0.3898 0.374 548740.0 101509.047619048 0.94277384940901 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O22 mock treatment 474670.0 51400.0 0.52 451450.0 45000.0 0.47 1.0403 0.9402 534090.0 86859.047619048 0.806710737619453 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O23 mock treatment 438600.0 15300.0 0.16 480050.0 73600.0 0.77 0.8955 0.6792 428000.0 -19230.952380952 -0.17860909376308 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base O24 mock treatment 461890.0 38600.0 0.39 422880.0 16400.0 0.17 0.9155 0.8954 496850.0 49619.047619048 0.460841093725726 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P01 mock treatment 460090.0 36800.0 0.37 466030.0 59600.0 0.62 -0.3413 -0.2423 372360.0 -74870.952380952 -0.695370291030722 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P02 mock treatment 316010.0 -107000.0 -1.09 428420.0 22000.0 0.23 -0.9442 -0.6477 346490.0 -100740.952380952 -0.935640100040677 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P03 mock treatment 364710.0 -58600.0 -0.6 379010.0 -27500.0 -0.29 -0.9331 -0.7904 446680.0 -550.952380952018 -0.00511701675086669 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P04 mock treatment 393350.0 -29900.0 -0.3 335110.0 -71400.0 -0.75 -0.9574 -0.7065 469400.0 22169.047619048 0.205896901328228 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P05 mock treatment 382890.0 -40400.0 -0.41 383680.0 -22800.0 -0.24 -1.045 -0.9261 362080.0 -85150.952380952 -0.790846658893974 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P06 mock treatment 351040.0 -72200.0 -0.73 297920.0 -109000.0 -1.14 -1.0085 -0.6497 496700.0 49469.047619048 0.459447956062351 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P07 mock treatment 335620.0 -87700.0 -0.89 392250.0 -14200.0 -0.15 -1.398 -0.8844 381280.0 -65950.952380952 -0.612525037982063 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P08 mock treatment 401400.0 -21900.0 -0.22 410400.0 3930.0 0.04 -0.6591 -0.7681 371040.0 -76190.952380952 -0.707629902468416 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P09 mock treatment 430460.0 7180.0 0.07 401320.0 -5150.0 -0.05 -0.5734 -0.5524 336930.0 -110300.952380952 -1.02442940711973 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P10 mock treatment 424970.0 1690.0 0.02 332670.0 -73800.0 -0.77 -0.974 -0.8459 373020.0 -74210.952380952 -0.689240485311875 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P11 mock treatment 377380.0 -45900.0 -0.47 379630.0 -26800.0 -0.28 -0.8247 -0.9833 399600.0 -47630.952380952 -0.442376491361948 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P12 mock treatment 381280.0 -42000.0 -0.43 347840.0 -58600.0 -0.61 -0.5528 -0.4601 515270.0 68039.047619048 0.63191839878809 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P13 mock treatment 352600.0 -70700.0 -0.72 436560.0 30100.0 0.32 -0.9387 -0.7171 375870.0 -71360.952380952 -0.662770869707763 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P14 mock treatment 348890.0 -74400.0 -0.76 437670.0 31200.0 0.33 -1.0436 -0.726 349250.0 -97980.952380952 -0.91000636703459 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P15 mock treatment 485660.0 62400.0 0.63 396840.0 -9630.0 -0.1 -0.4598 -0.3791 364320.0 -82910.952380952 -0.770042469787585 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P16 mock treatment 379550.0 -43700.0 -0.44 443960.0 37500.0 0.39 -0.4195 -0.4865 426630.0 -20600.952380952 -0.191333084421899 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P17 mock treatment 385280.0 -38000.0 -0.39 387450.0 -19000.0 -0.2 -0.8662 -0.8702 356560.0 -90670.952380952 -0.842114124906148 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P18 mock treatment 350040.0 -73200.0 -0.74 354480.0 -52000.0 -0.54 -0.7274 -0.7358 412740.0 -34490.952380952 -0.320337632050359 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P19 mock treatment 416250.0 -7030.0 -0.07 368110.0 -38400.0 -0.4 -0.7543 -0.7919 357040.0 -90190.952380952 -0.837656084383351 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P20 mock treatment 410000.0 -13300.0 -0.13 425760.0 19300.0 0.2 -0.485 -0.5475 358400.0 -88830.952380952 -0.825024969568757 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P21 mock treatment 389970.0 -33300.0 -0.34 372580.0 -33900.0 -0.36 -0.8317 -0.9857 397510.0 -49720.952380952 -0.461787542804964 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P22 mock treatment 366520.0 -56800.0 -0.58 381920.0 -24500.0 -0.26 -0.9309 -0.9522 404800.0 -42430.952380952 -0.394081052364972 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P23 mock treatment 336250.0 -87000.0 -0.88 357920.0 -48500.0 -0.51 -1.2999 -0.9519 358690.0 -88540.952380952 -0.822331570086233 1001.0069 CellTiterGlo(1001.0069) MODYPatientCellProfiling 1001.0069.Base P24 mock treatment 386460.0 -36800.0 -0.37 349280.0 -57200.0 -0.6 -1.0959 -0.9666 365650.0 -81580.952380952 -0.757689982505666