ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A01 compound treatment 120490.0 -252000.0 -1.42 98240.0 -249000.0 -1.45 -2.0249 -1.0 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A02 compound treatment 110030.0 -262000.0 -1.48 120990.0 -226000.0 -1.31 -1.9733 -0.9983 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A03 compound treatment 226300.0 -146000.0 -0.82 326470.0 -21000.0 -0.12 -0.6678 -0.8031 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A04 compound treatment 376560.0 4160.0 0.02 143530.0 -204000.0 -1.18 -0.8199 -0.693 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A05 compound treatment 178200.0 -194000.0 -1.09 134880.0 -213000.0 -1.23 -1.6449 -0.9982 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A06 compound treatment 136050.0 -236000.0 -1.33 149140.0 -198000.0 -1.15 -1.7542 -0.9974 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A07 compound treatment 146290.0 -226000.0 -1.27 174490.0 -173000.0 -1.0 -1.6095 -0.9931 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A08 compound treatment 161350.0 -211000.0 -1.19 194660.0 -153000.0 -0.89 -1.4669 -0.9896 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A09 compound treatment 145370.0 -227000.0 -1.28 148290.0 -199000.0 -1.16 -1.7206 -0.9987 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A10 compound treatment 112440.0 -260000.0 -1.46 136410.0 -211000.0 -1.22 -1.9004 -0.9961 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A11 compound treatment 162780.0 -210000.0 -1.18 173820.0 -174000.0 -1.01 -1.5466 -0.9969 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A12 compound treatment 188910.0 -183000.0 -1.03 162630.0 -185000.0 -1.07 -1.4885 -0.9998 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A13 mock treatment 283590.0 -88800.0 -0.5 264690.0 -82800.0 -0.48 -0.6931 -0.9998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A14 mock treatment 202690.0 -170000.0 -0.96 290530.0 -57000.0 -0.33 -0.9092 -0.8993 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A15 compound treatment 182020.0 -190000.0 -1.07 159680.0 -188000.0 -1.09 -1.528 -1.0 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A16 compound treatment 206420.0 -166000.0 -0.93 197880.0 -150000.0 -0.87 -1.2743 -0.9993 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A17 compound treatment 288060.0 -84300.0 -0.47 311560.0 -35900.0 -0.21 -0.4831 -0.9317 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A18 compound treatment 175420.0 -197000.0 -1.11 145170.0 -202000.0 -1.17 -1.6138 -0.9996 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A19 compound treatment 117920.0 -254000.0 -1.43 137880.0 -210000.0 -1.22 -1.8726 -0.9967 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A20 compound treatment 161920.0 -210000.0 -1.18 280900.0 -66600.0 -0.39 -1.1109 -0.8914 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A21 compound treatment 225930.0 -146000.0 -0.82 297760.0 -49700.0 -0.29 -0.787 -0.9009 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A22 compound treatment 309920.0 -62500.0 -0.35 219390.0 -128000.0 -0.74 -0.774 -0.9417 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A23 compound treatment 139200.0 -233000.0 -1.31 241490.0 -106000.0 -0.61 -1.363 -0.9402 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 A24 compound treatment 231230.0 -141000.0 -0.79 151310.0 -196000.0 -1.14 -1.3665 -0.9846 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B01 compound treatment 185640.0 -187000.0 -1.05 267200.0 -80300.0 -0.47 -1.0727 -0.9329 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B02 compound treatment 238940.0 -133000.0 -0.75 440930.0 93400.0 0.54 -0.1481 -0.1599 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B03 compound treatment 320120.0 -52300.0 -0.29 360980.0 13500.0 0.08 -0.1528 -0.5017 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B04 compound treatment 223170.0 -149000.0 -0.84 263610.0 -83900.0 -0.49 -0.938 -0.9663 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B05 compound treatment 257920.0 -114000.0 -0.64 189070.0 -158000.0 -0.92 -1.1054 -0.985 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B06 compound treatment 482280.0 110000.0 0.62 361870.0 14400.0 0.08 0.4963 0.7953 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B07 compound treatment 363740.0 -8660.0 -0.05 210690.0 -137000.0 -0.79 -0.5955 -0.7492 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B08 compound treatment 123270.0 -249000.0 -1.4 196980.0 -151000.0 -0.87 -1.6089 -0.974 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B09 compound treatment 200820.0 -172000.0 -0.97 195040.0 -152000.0 -0.88 -1.3082 -0.999 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B10 compound treatment 199360.0 -173000.0 -0.97 286490.0 -61000.0 -0.35 -0.939 -0.906 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B11 compound treatment 144480.0 -228000.0 -1.28 135940.0 -212000.0 -1.23 -1.7748 -0.9997 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B12 compound treatment 347520.0 -24900.0 -0.14 383520.0 36000.0 0.21 0.0487 0.1936 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B13 mock treatment 463200.0 90800.0 0.51 289030.0 -58500.0 -0.34 0.1217 0.1984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B14 mock treatment 468750.0 96300.0 0.54 457810.0 110000.0 0.64 0.8359 0.9966 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B15 compound treatment 301540.0 -70900.0 -0.4 347590.0 100.0 0.0 -0.2817 -0.7061 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B16 compound treatment 198410.0 -174000.0 -0.98 347780.0 290.0 0.0 -0.6914 -0.7059 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B17 compound treatment 257920.0 -114000.0 -0.64 161480.0 -186000.0 -1.08 -1.2185 -0.9697 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B18 compound treatment 346280.0 -26100.0 -0.15 259810.0 -87700.0 -0.51 -0.4636 -0.8757 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B19 compound treatment 246570.0 -126000.0 -0.71 253440.0 -94000.0 -0.55 -0.8866 -0.9917 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B20 compound treatment 223200.0 -149000.0 -0.84 181280.0 -166000.0 -0.96 -1.2755 -0.9976 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B21 compound treatment 307360.0 -65000.0 -0.37 160930.0 -187000.0 -1.08 -1.024 -0.8965 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B22 compound treatment 398570.0 26200.0 0.15 388210.0 40700.0 0.24 0.2711 0.9742 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B23 compound treatment 317300.0 -55100.0 -0.31 370080.0 22600.0 0.13 -0.1267 -0.3763 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 B24 compound treatment 300710.0 -71700.0 -0.4 256330.0 -91200.0 -0.53 -0.6592 -0.9911 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C01 compound treatment 54240.0 -318000.0 -1.79 104870.0 -243000.0 -1.41 -2.2614 -0.9929 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C02 compound treatment 139320.0 -233000.0 -1.31 168320.0 -179000.0 -1.04 -1.6626 -0.9933 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C03 compound treatment 314370.0 -58000.0 -0.33 154760.0 -193000.0 -1.12 -1.0214 -0.8771 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C04 compound treatment 265400.0 -107000.0 -0.6 150880.0 -197000.0 -1.14 -1.2322 -0.9555 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C05 compound treatment 310760.0 -61600.0 -0.35 205930.0 -142000.0 -0.82 -0.8259 -0.9266 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C06 compound treatment 201130.0 -171000.0 -0.96 164240.0 -183000.0 -1.06 -1.4333 -0.9988 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C07 compound treatment 307870.0 -64500.0 -0.36 393920.0 46400.0 0.27 -0.0665 -0.147 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C08 compound treatment 245470.0 -127000.0 -0.71 177690.0 -170000.0 -0.98 -1.2016 -0.9876 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C09 compound treatment 349920.0 -22500.0 -0.13 192800.0 -155000.0 -0.9 -0.7239 -0.799 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C10 compound treatment 208960.0 -163000.0 -0.92 127140.0 -220000.0 -1.28 -1.5542 -0.987 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C11 mock treatment 287840.0 -84600.0 -0.48 421830.0 74300.0 0.43 -0.0318 -0.0495 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C12 mock treatment 319330.0 -53100.0 -0.3 235840.0 -112000.0 -0.65 -0.6691 -0.9383 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C13 compound treatment 243380.0 -129000.0 -0.73 163200.0 -184000.0 -1.07 -1.2693 -0.9823 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C14 compound treatment 195450.0 -177000.0 -1.0 206080.0 -141000.0 -0.82 -1.2843 -0.9953 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C15 mock treatment 380350.0 7950.0 0.04 304110.0 -43400.0 -0.25 -0.1463 -0.5724 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C16 mock treatment 395230.0 22800.0 0.13 396480.0 49000.0 0.28 0.2918 0.9357 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C17 compound treatment 193450.0 -179000.0 -1.01 178360.0 -169000.0 -0.98 -1.4059 -0.9999 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C18 compound treatment 249480.0 -123000.0 -0.69 164990.0 -182000.0 -1.06 -1.2377 -0.9788 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C19 compound treatment 232160.0 -140000.0 -0.79 181290.0 -166000.0 -0.96 -1.2398 -0.9951 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C20 compound treatment 232870.0 -140000.0 -0.79 244370.0 -103000.0 -0.6 -0.9783 -0.9909 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C21 compound treatment 192600.0 -180000.0 -1.01 215280.0 -132000.0 -0.77 -1.2579 -0.9906 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C22 compound treatment 212570.0 -160000.0 -0.9 166150.0 -181000.0 -1.05 -1.3799 -0.997 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C23 compound treatment 285530.0 -86900.0 -0.49 320740.0 -26700.0 -0.16 -0.4555 -0.8878 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 C24 compound treatment 293500.0 -78900.0 -0.44 314690.0 -32800.0 -0.19 -0.4486 -0.9284 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D01 compound treatment 283460.0 -88900.0 -0.5 387920.0 40400.0 0.23 -0.1883 -0.3405 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D02 compound treatment 397280.0 24900.0 0.14 424390.0 76900.0 0.45 0.4144 0.8865 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D03 compound treatment 304420.0 -68000.0 -0.38 342820.0 -4670.0 -0.03 -0.2898 -0.7553 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D04 compound treatment 350650.0 -21800.0 -0.12 320590.0 -26900.0 -0.16 -0.1969 -0.9928 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D05 compound treatment 317240.0 -55200.0 -0.31 189150.0 -158000.0 -0.92 -0.8689 -0.8964 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D06 compound treatment 290620.0 -81800.0 -0.46 187220.0 -160000.0 -0.93 -0.9828 -0.9475 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D07 compound treatment 240660.0 -132000.0 -0.74 420510.0 73000.0 0.42 -0.225 -0.2634 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D08 compound treatment 260480.0 -112000.0 -0.63 103550.0 -244000.0 -1.41 -1.4459 -0.9336 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D09 compound treatment 322840.0 -49600.0 -0.28 166950.0 -181000.0 -1.05 -0.9377 -0.8653 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D10 compound treatment 463720.0 91300.0 0.51 336230.0 -11300.0 -0.07 0.3173 0.6124 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D11 mock treatment 444890.0 72500.0 0.41 413470.0 66000.0 0.38 0.5591 0.9995 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D12 mock treatment 264930.0 -107000.0 -0.61 258480.0 -89000.0 -0.52 -0.7928 -0.9969 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D13 compound treatment 258400.0 -114000.0 -0.64 271700.0 -75800.0 -0.44 -0.7646 -0.983 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D14 compound treatment 259640.0 -113000.0 -0.63 290610.0 -56900.0 -0.33 -0.6821 -0.9535 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D15 mock treatment 338660.0 -33700.0 -0.19 308130.0 -39400.0 -0.23 -0.2957 -0.9958 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D16 mock treatment 271850.0 -101000.0 -0.57 247550.0 -99900.0 -0.58 -0.8101 -0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D17 compound treatment 367270.0 -5130.0 -0.03 235680.0 -112000.0 -0.65 -0.4789 -0.7379 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D18 compound treatment 247390.0 -125000.0 -0.7 349640.0 2150.0 0.01 -0.4888 -0.6945 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D19 compound treatment 338140.0 -34300.0 -0.19 194730.0 -153000.0 -0.89 -0.7628 -0.8414 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D20 compound treatment 335360.0 -37000.0 -0.21 289030.0 -58500.0 -0.34 -0.3872 -0.9728 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D21 compound treatment 336690.0 -35700.0 -0.2 222960.0 -125000.0 -0.72 -0.6528 -0.8708 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D22 compound treatment 219410.0 -153000.0 -0.86 341070.0 -6420.0 -0.04 -0.6353 -0.737 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D23 compound treatment 221330.0 -151000.0 -0.85 205250.0 -142000.0 -0.82 -1.1847 -0.9999 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 D24 compound treatment 231410.0 -141000.0 -0.79 182170.0 -165000.0 -0.96 -1.2392 -0.9956 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E01 mock treatment 435950.0 63500.0 0.36 472990.0 126000.0 0.73 0.7676 0.9465 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E02 mock treatment 441600.0 69200.0 0.39 436160.0 88700.0 0.51 0.6391 0.9906 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E03 compound treatment 264800.0 -108000.0 -0.61 180700.0 -167000.0 -0.97 -1.1123 -0.9746 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E04 compound treatment 380030.0 7630.0 0.04 301960.0 -45500.0 -0.26 -0.1564 -0.5845 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E05 compound treatment 449880.0 77500.0 0.44 446580.0 99100.0 0.57 0.7148 0.9907 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E06 compound treatment 384020.0 11600.0 0.07 363680.0 16200.0 0.09 0.1126 0.9844 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E07 compound treatment 173120.0 -199000.0 -1.12 150300.0 -197000.0 -1.14 -1.6019 -1.0 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E08 compound treatment 346040.0 -26400.0 -0.15 328430.0 -19100.0 -0.11 -0.1831 -0.9895 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E09 mock treatment 462950.0 90500.0 0.51 455750.0 108000.0 0.63 0.8044 0.9947 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E10 mock treatment 461920.0 89500.0 0.5 230650.0 -117000.0 -0.68 -0.1228 -0.1454 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E11 compound treatment 386580.0 14200.0 0.08 175840.0 -172000.0 -1.0 -0.6475 -0.6483 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E12 compound treatment 286360.0 -86000.0 -0.48 171680.0 -176000.0 -1.02 -1.0635 -0.9421 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E13 compound treatment 296000.0 -76400.0 -0.43 224660.0 -123000.0 -0.71 -0.8078 -0.9708 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E14 compound treatment 408920.0 36500.0 0.21 259780.0 -87700.0 -0.51 -0.2143 -0.3907 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E15 compound treatment 322300.0 -50100.0 -0.28 290960.0 -56500.0 -0.33 -0.4313 -0.9972 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E16 compound treatment 233520.0 -139000.0 -0.78 279140.0 -68300.0 -0.4 -0.8331 -0.9504 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E17 mock treatment 474670.0 102000.0 0.58 273190.0 -74300.0 -0.43 0.1024 0.1424 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E18 mock treatment 410890.0 38500.0 0.22 272000.0 -75500.0 -0.44 -0.1564 -0.3201 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E19 compound treatment 369770.0 -2630.0 -0.01 379040.0 31600.0 0.18 0.1189 0.6477 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E20 compound treatment 313850.0 -58600.0 -0.33 167810.0 -180000.0 -1.04 -0.9699 -0.8874 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E21 compound treatment 362940.0 -9460.0 -0.05 263710.0 -83800.0 -0.49 -0.3812 -0.78 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E22 compound treatment 338400.0 -34000.0 -0.19 222720.0 -125000.0 -0.72 -0.647 -0.8644 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E23 compound treatment 303040.0 -69400.0 -0.39 193760.0 -154000.0 -0.89 -0.9065 -0.9314 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 E24 compound treatment 354100.0 -18300.0 -0.1 198270.0 -149000.0 -0.87 -0.6848 -0.7858 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F01 mock treatment 177460.0 -195000.0 -1.1 412710.0 65200.0 0.38 -0.5086 -0.4381 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F02 mock treatment 459950.0 87500.0 0.49 290240.0 -57200.0 -0.33 0.1137 0.1914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F03 compound treatment 217680.0 -155000.0 -0.87 217040.0 -130000.0 -0.76 -1.1509 -0.9975 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F04 compound treatment 237440.0 -135000.0 -0.76 183960.0 -164000.0 -0.95 -1.2079 -0.994 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F05 compound treatment 169160.0 -203000.0 -1.14 317440.0 -30000.0 -0.17 -0.9323 -0.8055 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F06 compound treatment 175520.0 -197000.0 -1.11 238370.0 -109000.0 -0.63 -1.2312 -0.9647 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F07 compound treatment 384820.0 12400.0 0.07 347790.0 300.0 0.0 0.0507 0.7245 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F08 compound treatment 248700.0 -124000.0 -0.7 150300.0 -197000.0 -1.14 -1.3011 -0.9717 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F09 mock treatment 287520.0 -84900.0 -0.48 487220.0 140000.0 0.81 0.2351 0.2499 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F10 mock treatment 465480.0 93100.0 0.52 439750.0 92300.0 0.54 0.7488 0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F11 compound treatment 221950.0 -150000.0 -0.85 265470.0 -82000.0 -0.48 -0.9353 -0.9628 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F12 compound treatment 411640.0 39200.0 0.22 459530.0 112000.0 0.65 0.6156 0.8971 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F13 compound treatment 229510.0 -143000.0 -0.8 223050.0 -124000.0 -0.72 -1.0791 -0.9985 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F14 compound treatment 290140.0 -82300.0 -0.46 247680.0 -99800.0 -0.58 -0.7368 -0.9939 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F15 compound treatment 214050.0 -158000.0 -0.89 139860.0 -208000.0 -1.2 -1.4818 -0.9891 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F16 compound treatment 216210.0 -156000.0 -0.88 243040.0 -104000.0 -0.61 -1.0501 -0.9835 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F17 mock treatment 313000.0 -59400.0 -0.33 420930.0 73400.0 0.43 0.0647 0.1195 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F18 mock treatment 316810.0 -55600.0 -0.31 370850.0 23400.0 0.14 -0.1255 -0.368 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F19 compound treatment 226300.0 -146000.0 -0.82 200110.0 -147000.0 -0.85 -1.186 -0.9998 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F20 compound treatment 346640.0 -25800.0 -0.15 359880.0 12400.0 0.07 -0.0518 -0.3197 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F21 compound treatment 278080.0 -94300.0 -0.53 254080.0 -93400.0 -0.54 -0.7585 -1.0 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F22 compound treatment 375380.0 2980.0 0.02 353780.0 6290.0 0.04 0.0376 0.9376 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F23 compound treatment 202110.0 -170000.0 -0.96 201180.0 -146000.0 -0.85 -1.2779 -0.9981 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 F24 compound treatment 345440.0 -27000.0 -0.15 299540.0 -47900.0 -0.28 -0.304 -0.9595 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G01 compound treatment 240880.0 -132000.0 -0.74 200480.0 -147000.0 -0.85 -1.1264 -0.9975 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G02 compound treatment 372100.0 -305.0 0.0 316750.0 -30700.0 -0.18 -0.1273 -0.7139 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G03 mock treatment 429320.0 56900.0 0.32 431920.0 84400.0 0.49 0.5728 0.9789 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G04 mock treatment 299730.0 -72700.0 -0.41 427400.0 79900.0 0.46 0.0384 0.0621 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G05 compound treatment 227170.0 -145000.0 -0.82 350210.0 2720.0 0.02 -0.567 -0.6933 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G06 compound treatment 400960.0 28600.0 0.16 216290.0 -131000.0 -0.76 -0.4244 -0.5457 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G07 compound treatment 473890.0 101000.0 0.57 141610.0 -206000.0 -1.19 -0.4403 -0.3326 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G08 compound treatment 325960.0 -46400.0 -0.26 384830.0 37300.0 0.22 -0.0318 -0.0935 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G09 compound treatment 404240.0 31800.0 0.18 317170.0 -30300.0 -0.18 0.0024 0.0095 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G10 compound treatment 350180.0 -22200.0 -0.13 148980.0 -199000.0 -1.15 -0.9025 -0.7794 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G11 compound treatment 416910.0 44500.0 0.25 284670.0 -62800.0 -0.36 -0.0805 -0.182 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G12 compound treatment 292320.0 -80100.0 -0.45 141730.0 -206000.0 -1.19 -1.1626 -0.9114 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G13 compound treatment 101830.0 -271000.0 -1.52 148330.0 -199000.0 -1.16 -1.8938 -0.9907 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G14 compound treatment 309140.0 -63300.0 -0.36 334600.0 -12900.0 -0.07 -0.3047 -0.8373 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G15 compound treatment 258240.0 -114000.0 -0.64 235890.0 -112000.0 -0.65 -0.9121 -1.0 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G16 compound treatment 230320.0 -142000.0 -0.8 192990.0 -154000.0 -0.9 -1.1992 -0.9984 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G17 compound treatment 252910.0 -119000.0 -0.67 348320.0 830.0 0.0 -0.4723 -0.702 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G18 compound treatment 351280.0 -21100.0 -0.12 230960.0 -117000.0 -0.68 -0.562 -0.819 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G19 mock treatment 461060.0 88700.0 0.5 409220.0 61700.0 0.36 0.6061 0.9867 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G20 mock treatment 251520.0 -121000.0 -0.68 380980.0 33500.0 0.19 -0.3439 -0.4859 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G21 compound treatment 388980.0 16600.0 0.09 248580.0 -98900.0 -0.57 -0.3396 -0.5844 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G22 compound treatment 283240.0 -89200.0 -0.5 205500.0 -142000.0 -0.82 -0.9372 -0.9718 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G23 compound treatment 356860.0 -15500.0 -0.09 295390.0 -52100.0 -0.3 -0.2755 -0.8759 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 G24 compound treatment 377660.0 5260.0 0.03 163730.0 -184000.0 -1.07 -0.7326 -0.6872 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H01 compound treatment 131890.0 -241000.0 -1.35 235910.0 -112000.0 -0.65 -1.415 -0.9429 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H02 compound treatment 227600.0 -145000.0 -0.82 148830.0 -199000.0 -1.15 -1.3911 -0.9856 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H03 mock treatment 491230.0 119000.0 0.67 300360.0 -47100.0 -0.27 0.2797 0.3871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H04 mock treatment 399950.0 27500.0 0.16 486880.0 139000.0 0.81 0.6813 0.8277 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H05 compound treatment 298280.0 -74100.0 -0.42 355840.0 8350.0 0.05 -0.2608 -0.6209 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H06 compound treatment 268580.0 -104000.0 -0.58 430740.0 83300.0 0.48 -0.0719 -0.0948 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H07 compound treatment 211130.0 -161000.0 -0.91 179450.0 -168000.0 -0.97 -1.3311 -0.9994 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H08 compound treatment 402970.0 30600.0 0.17 321450.0 -26000.0 -0.15 0.0149 0.065 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H09 compound treatment 214500.0 -158000.0 -0.89 231520.0 -116000.0 -0.67 -1.1041 -0.9905 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H10 compound treatment 344910.0 -27500.0 -0.15 155790.0 -192000.0 -1.11 -0.8956 -0.7979 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H11 compound treatment 190850.0 -182000.0 -1.02 219560.0 -128000.0 -0.74 -1.2473 -0.9876 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H12 compound treatment 130400.0 -242000.0 -1.36 155520.0 -192000.0 -1.11 -1.7506 -0.995 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H13 compound treatment 173630.0 -199000.0 -1.12 295040.0 -52400.0 -0.3 -1.0063 -0.8678 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H14 compound treatment 182840.0 -190000.0 -1.07 152220.0 -195000.0 -1.13 -1.5554 -0.9996 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H15 compound treatment 269140.0 -103000.0 -0.58 213510.0 -134000.0 -0.78 -0.9605 -0.9898 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H16 compound treatment 313540.0 -58900.0 -0.33 236270.0 -111000.0 -0.65 -0.6904 -0.9521 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H17 compound treatment 231070.0 -141000.0 -0.8 279120.0 -68400.0 -0.4 -0.843 -0.9483 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H18 compound treatment 381390.0 8990.0 0.05 326790.0 -20700.0 -0.12 -0.0491 -0.3771 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H19 mock treatment 467960.0 95600.0 0.54 300930.0 -46600.0 -0.27 0.1894 0.3147 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H20 mock treatment 499530.0 127000.0 0.72 332690.0 -14800.0 -0.09 0.4454 0.6179 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H21 compound treatment 289980.0 -82400.0 -0.46 193780.0 -154000.0 -0.89 -0.9584 -0.9537 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H22 compound treatment 224000.0 -148000.0 -0.84 179880.0 -168000.0 -0.97 -1.2781 -0.9972 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H23 compound treatment 291900.0 -80500.0 -0.45 237950.0 -110000.0 -0.64 -0.7697 -0.9863 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 H24 compound treatment 286480.0 -85900.0 -0.48 222520.0 -125000.0 -0.72 -0.8545 -0.9807 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I01 compound treatment 331170.0 -41200.0 -0.23 394320.0 46800.0 0.27 0.0279 0.0781 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I02 compound treatment 260130.0 -112000.0 -0.63 204590.0 -143000.0 -0.83 -1.0329 -0.9911 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I03 compound treatment 228000.0 -144000.0 -0.81 266140.0 -81300.0 -0.47 -0.9084 -0.9665 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I04 compound treatment 278270.0 -94100.0 -0.53 332560.0 -14900.0 -0.09 -0.4359 -0.8119 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I05 mock treatment 477470.0 105000.0 0.59 355310.0 7820.0 0.05 0.4503 0.7591 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I06 mock treatment 433880.0 61500.0 0.35 295290.0 -52200.0 -0.3 0.0307 0.0667 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I07 compound treatment 331290.0 -41100.0 -0.23 283910.0 -63600.0 -0.37 -0.4244 -0.9748 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I08 compound treatment 307360.0 -65000.0 -0.37 349410.0 1920.0 0.01 -0.251 -0.6853 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I09 compound treatment 344170.0 -28200.0 -0.16 402880.0 55400.0 0.32 0.1148 0.3202 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I10 compound treatment 422100.0 49700.0 0.28 178660.0 -169000.0 -0.98 -0.4945 -0.4856 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I11 compound treatment 274610.0 -97800.0 -0.55 231280.0 -116000.0 -0.67 -0.8658 -0.995 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I12 compound treatment 178000.0 -194000.0 -1.09 197490.0 -150000.0 -0.87 -1.389 -0.9935 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I13 compound treatment 487250.0 115000.0 0.65 302560.0 -44900.0 -0.26 0.2729 0.3915 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I14 compound treatment 279140.0 -93300.0 -0.53 250080.0 -97400.0 -0.56 -0.7707 -0.9993 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I15 compound treatment 276010.0 -96400.0 -0.54 372870.0 25400.0 0.15 -0.2796 -0.4973 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I16 compound treatment 305350.0 -67100.0 -0.38 161680.0 -186000.0 -1.08 -1.0289 -0.9011 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I17 compound treatment 441390.0 69000.0 0.39 334880.0 -12600.0 -0.07 0.2229 0.564 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I18 compound treatment 418900.0 46500.0 0.26 367960.0 20500.0 0.12 0.269 0.936 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I19 compound treatment 322880.0 -49500.0 -0.28 235780.0 -112000.0 -0.65 -0.6552 -0.929 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I20 compound treatment 334950.0 -37500.0 -0.21 241250.0 -106000.0 -0.62 -0.5848 -0.898 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I21 mock treatment 339400.0 -33000.0 -0.19 315200.0 -32300.0 -0.19 -0.2638 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I22 mock treatment 346820.0 -25600.0 -0.14 398880.0 51400.0 0.3 0.1089 0.329 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I23 compound treatment 324060.0 -48300.0 -0.27 199690.0 -148000.0 -0.86 -0.7985 -0.8879 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 I24 compound treatment 321920.0 -50500.0 -0.28 251050.0 -96400.0 -0.56 -0.5964 -0.9507 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J01 compound treatment 106730.0 -266000.0 -1.5 197310.0 -150000.0 -0.87 -1.6734 -0.9669 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J02 compound treatment 170790.0 -202000.0 -1.13 231680.0 -116000.0 -0.67 -1.2775 -0.9686 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J03 compound treatment 221760.0 -151000.0 -0.85 309800.0 -37700.0 -0.22 -0.7542 -0.8612 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J04 compound treatment 147000.0 -225000.0 -1.27 237600.0 -110000.0 -0.64 -1.3479 -0.9492 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J05 mock treatment 349950.0 -22500.0 -0.13 149360.0 -198000.0 -1.15 -0.9019 -0.7802 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J06 mock treatment 363050.0 -9350.0 -0.05 412880.0 65400.0 0.38 0.2309 0.6031 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J07 compound treatment 195080.0 -177000.0 -1.0 170560.0 -177000.0 -1.03 -1.4314 -0.9999 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J08 compound treatment 235880.0 -137000.0 -0.77 220580.0 -127000.0 -0.74 -1.0639 -0.9998 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J09 compound treatment 337660.0 -34700.0 -0.2 224560.0 -123000.0 -0.71 -0.6424 -0.869 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J10 compound treatment 265930.0 -106000.0 -0.6 142040.0 -205000.0 -1.19 -1.2664 -0.9495 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J11 compound treatment 294910.0 -77500.0 -0.44 70140.0 -277000.0 -1.61 -1.4458 -0.8675 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J12 compound treatment 461930.0 89500.0 0.5 177180.0 -170000.0 -0.99 -0.342 -0.3085 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J13 compound treatment 284400.0 -88000.0 -0.5 173240.0 -174000.0 -1.01 -1.0649 -0.9462 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J14 compound treatment 173860.0 -199000.0 -1.12 96640.0 -251000.0 -1.45 -1.819 -0.9915 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J15 compound treatment 366560.0 -5840.0 -0.03 259850.0 -87600.0 -0.51 -0.3827 -0.7513 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J16 compound treatment 291250.0 -81200.0 -0.46 335200.0 -12300.0 -0.07 -0.3734 -0.8076 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J17 compound treatment 284180.0 -88200.0 -0.5 302280.0 -45200.0 -0.26 -0.5366 -0.9554 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J18 compound treatment 299040.0 -73400.0 -0.41 195130.0 -152000.0 -0.88 -0.9168 -0.94 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J19 compound treatment 272340.0 -100000.0 -0.56 299110.0 -48400.0 -0.28 -0.5967 -0.9482 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J20 compound treatment 333570.0 -38800.0 -0.22 291890.0 -55600.0 -0.32 -0.3826 -0.9821 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J21 mock treatment 432480.0 60100.0 0.34 350150.0 2660.0 0.02 0.25 0.7386 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J22 mock treatment 390260.0 17900.0 0.1 316690.0 -30800.0 -0.18 -0.0552 -0.2695 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J23 compound treatment 301800.0 -70600.0 -0.4 284640.0 -62800.0 -0.36 -0.5388 -0.9991 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 J24 compound treatment 265920.0 -106000.0 -0.6 171940.0 -176000.0 -1.02 -1.1438 -0.9681 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K01 compound treatment 364750.0 -7650.0 -0.04 320760.0 -26700.0 -0.16 -0.1401 -0.8707 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K02 compound treatment 227650.0 -145000.0 -0.81 337520.0 -9970.0 -0.06 -0.6171 -0.7554 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K03 compound treatment 387370.0 15000.0 0.08 274580.0 -72900.0 -0.42 -0.2394 -0.5553 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K04 compound treatment 301800.0 -70600.0 -0.4 191280.0 -156000.0 -0.91 -0.9216 -0.9316 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K05 compound treatment 203880.0 -169000.0 -0.95 217440.0 -130000.0 -0.75 -1.2042 -0.9935 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K06 compound treatment 210360.0 -162000.0 -0.91 278660.0 -68800.0 -0.4 -0.9273 -0.9313 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K07 mock treatment 396800.0 24400.0 0.14 198990.0 -148000.0 -0.86 -0.5119 -0.5869 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K08 mock treatment 443280.0 70900.0 0.4 286950.0 -60500.0 -0.35 0.0339 0.0637 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K09 compound treatment 368570.0 -3830.0 -0.02 170560.0 -177000.0 -1.03 -0.7408 -0.7218 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K10 compound treatment 314820.0 -57600.0 -0.32 234920.0 -113000.0 -0.65 -0.6909 -0.9478 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K11 compound treatment 277180.0 -95200.0 -0.54 209510.0 -138000.0 -0.8 -0.9449 -0.981 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K12 compound treatment 193600.0 -179000.0 -1.01 203070.0 -144000.0 -0.84 -1.304 -0.9958 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K13 compound treatment 315040.0 -57400.0 -0.32 432500.0 85000.0 0.49 0.1203 0.2041 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K14 compound treatment 255840.0 -117000.0 -0.66 311520.0 -36000.0 -0.21 -0.6115 -0.8881 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K15 mock treatment 342780.0 -29600.0 -0.17 256370.0 -91100.0 -0.53 -0.4916 -0.8871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K16 mock treatment 437630.0 65200.0 0.37 324070.0 -23400.0 -0.14 0.1636 0.4179 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K17 compound treatment 474440.0 102000.0 0.57 361350.0 13900.0 0.08 0.463 0.7983 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K18 compound treatment 332480.0 -39900.0 -0.22 297940.0 -49500.0 -0.29 -0.3621 -0.9926 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K19 compound treatment 232480.0 -140000.0 -0.79 229300.0 -118000.0 -0.69 -1.0417 -0.9976 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K20 compound treatment 347550.0 -24900.0 -0.14 232430.0 -115000.0 -0.67 -0.5708 -0.8372 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K21 compound treatment 407880.0 35500.0 0.2 428420.0 80900.0 0.47 0.4731 0.9275 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K22 compound treatment 337880.0 -34500.0 -0.19 220960.0 -127000.0 -0.73 -0.6563 -0.8646 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K23 mock treatment 461250.0 88800.0 0.5 356290.0 8800.0 0.05 0.3898 0.7752 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 K24 mock treatment 350250.0 -22200.0 -0.12 318970.0 -28500.0 -0.17 -0.2051 -0.9903 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L01 compound treatment 104550.0 -268000.0 -1.51 123420.0 -224000.0 -1.3 -1.9851 -0.9973 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L02 compound treatment 246880.0 -126000.0 -0.71 192900.0 -155000.0 -0.9 -1.1336 -0.9931 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L03 compound treatment 202310.0 -170000.0 -0.96 221040.0 -126000.0 -0.73 -1.1956 -0.9913 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L04 compound treatment 232270.0 -140000.0 -0.79 127450.0 -220000.0 -1.28 -1.4602 -0.9733 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L05 compound treatment 219080.0 -153000.0 -0.86 171400.0 -176000.0 -1.02 -1.3324 -0.9965 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L06 compound treatment 206810.0 -166000.0 -0.93 214020.0 -133000.0 -0.77 -1.2065 -0.9957 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L07 mock treatment 321040.0 -51400.0 -0.29 409340.0 61900.0 0.36 0.0492 0.1067 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L08 mock treatment 431890.0 59500.0 0.33 505090.0 158000.0 0.91 0.8831 0.9072 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L09 compound treatment 383720.0 11300.0 0.06 234260.0 -113000.0 -0.66 -0.4193 -0.6355 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L10 compound treatment 418280.0 45900.0 0.26 457120.0 110000.0 0.64 0.6322 0.9212 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L11 compound treatment 221490.0 -151000.0 -0.85 274440.0 -73000.0 -0.42 -0.9003 -0.9483 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L12 compound treatment 231160.0 -141000.0 -0.8 251310.0 -96200.0 -0.56 -0.9567 -0.985 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L13 compound treatment 293000.0 -79400.0 -0.45 191160.0 -156000.0 -0.91 -0.9572 -0.9469 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L14 compound treatment 240550.0 -132000.0 -0.74 151320.0 -196000.0 -1.14 -1.3293 -0.9786 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L15 mock treatment 349070.0 -23300.0 -0.13 350200.0 2710.0 0.02 -0.0818 -0.6181 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L16 mock treatment 224690.0 -148000.0 -0.83 253970.0 -93500.0 -0.54 -0.9715 -0.9786 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L17 compound treatment 329920.0 -42500.0 -0.24 264810.0 -82700.0 -0.48 -0.5082 -0.9484 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L18 compound treatment 315710.0 -56700.0 -0.32 208390.0 -139000.0 -0.81 -0.7961 -0.9177 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L19 compound treatment 313760.0 -58600.0 -0.33 220600.0 -127000.0 -0.74 -0.7538 -0.9346 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L20 compound treatment 254580.0 -118000.0 -0.66 287110.0 -60400.0 -0.35 -0.7166 -0.9554 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L21 compound treatment 277670.0 -94700.0 -0.53 209200.0 -138000.0 -0.8 -0.9442 -0.9804 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L22 compound treatment 240320.0 -132000.0 -0.74 239040.0 -108000.0 -0.63 -0.9705 -0.9965 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L23 mock treatment 435300.0 62900.0 0.35 409600.0 62100.0 0.36 0.5051 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 L24 mock treatment 364500.0 -7900.0 -0.04 239870.0 -108000.0 -0.62 -0.4728 -0.7556 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M01 compound treatment 202820.0 -170000.0 -0.95 115320.0 -232000.0 -1.35 -1.6271 -0.9858 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M02 compound treatment 208030.0 -164000.0 -0.93 189530.0 -158000.0 -0.92 -1.3021 -1.0 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M03 compound treatment 233730.0 -139000.0 -0.78 238150.0 -109000.0 -0.63 -1.0004 -0.9947 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M04 compound treatment 375040.0 2640.0 0.01 250560.0 -96900.0 -0.56 -0.387 -0.6882 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M05 compound treatment 371360.0 -1040.0 -0.01 292010.0 -55500.0 -0.32 -0.2317 -0.7199 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M06 compound treatment 318560.0 -53800.0 -0.3 282270.0 -65200.0 -0.38 -0.4818 -0.994 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M07 compound treatment 424230.0 51800.0 0.29 258960.0 -88500.0 -0.51 -0.1567 -0.2654 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M08 compound treatment 185120.0 -187000.0 -1.05 176560.0 -171000.0 -0.99 -1.4465 -0.9995 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M09 mock treatment 395320.0 22900.0 0.13 402850.0 55400.0 0.32 0.3182 0.9198 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M10 mock treatment 345120.0 -27300.0 -0.15 394240.0 46800.0 0.27 0.0831 0.2667 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M11 compound treatment 355050.0 -17400.0 -0.1 317890.0 -29600.0 -0.17 -0.1905 -0.9643 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M12 compound treatment 300800.0 -71600.0 -0.4 143560.0 -204000.0 -1.18 -1.1213 -0.8974 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M13 mock treatment 375380.0 2980.0 0.02 287120.0 -60400.0 -0.35 -0.2357 -0.6725 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M14 mock treatment 331160.0 -41200.0 -0.23 398480.0 51000.0 0.3 0.0449 0.1195 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M15 compound treatment 387480.0 15100.0 0.08 248440.0 -99000.0 -0.57 -0.3462 -0.5962 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M16 compound treatment 449050.0 76600.0 0.43 343760.0 -3730.0 -0.02 0.2898 0.6708 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M17 compound treatment 406670.0 34300.0 0.19 303380.0 -44100.0 -0.26 -0.0445 -0.1389 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M18 compound treatment 293140.0 -79300.0 -0.45 211220.0 -136000.0 -0.79 -0.8743 -0.9634 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M19 compound treatment 449150.0 76700.0 0.43 302610.0 -44900.0 -0.26 0.1215 0.2408 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M20 compound treatment 389680.0 17300.0 0.1 342980.0 -4510.0 -0.03 0.0503 0.4992 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M21 compound treatment 331040.0 -41400.0 -0.23 210750.0 -137000.0 -0.79 -0.7254 -0.8777 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M22 compound treatment 346560.0 -25800.0 -0.15 255140.0 -92300.0 -0.54 -0.4816 -0.8677 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M23 compound treatment 125280.0 -247000.0 -1.39 24830.0 -323000.0 -1.87 -2.3069 -0.9893 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 M24 compound treatment 354800.0 -17600.0 -0.1 138460.0 -209000.0 -1.21 -0.9273 -0.7624 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N01 compound treatment 190660.0 -182000.0 -1.02 165130.0 -182000.0 -1.06 -1.4713 -0.9999 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N02 compound treatment 203040.0 -169000.0 -0.95 279230.0 -68300.0 -0.4 -0.9541 -0.9242 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N03 compound treatment 199410.0 -173000.0 -0.97 167330.0 -180000.0 -1.04 -1.4274 -0.9994 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N04 compound treatment 268760.0 -104000.0 -0.58 343200.0 -4290.0 -0.02 -0.4302 -0.7366 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N05 compound treatment 245920.0 -126000.0 -0.71 167570.0 -180000.0 -1.04 -1.2413 -0.9826 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N06 compound treatment 252480.0 -120000.0 -0.68 297770.0 -49700.0 -0.29 -0.6813 -0.928 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N07 compound treatment 242160.0 -130000.0 -0.73 176670.0 -171000.0 -0.99 -1.219 -0.989 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N08 compound treatment 163750.0 -209000.0 -1.17 131100.0 -216000.0 -1.25 -1.718 -0.9995 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N09 mock treatment 284410.0 -88000.0 -0.5 426800.0 79300.0 0.46 -0.025 -0.037 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N10 mock treatment 337440.0 -35000.0 -0.2 241040.0 -106000.0 -0.62 -0.5757 -0.8885 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N11 compound treatment 185030.0 -187000.0 -1.05 168850.0 -179000.0 -1.04 -1.4784 -1.0 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N12 compound treatment 264910.0 -107000.0 -0.61 225820.0 -122000.0 -0.71 -0.9268 -0.9971 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N13 mock treatment 277040.0 -95400.0 -0.54 348900.0 1410.0 0.01 -0.3738 -0.6963 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N14 mock treatment 317440.0 -55000.0 -0.31 290310.0 -57200.0 -0.33 -0.4533 -0.9994 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N15 compound treatment 268820.0 -104000.0 -0.58 197150.0 -150000.0 -0.87 -1.0289 -0.9809 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N16 compound treatment 277400.0 -95000.0 -0.53 224340.0 -123000.0 -0.71 -0.8832 -0.9898 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N17 compound treatment 281510.0 -90900.0 -0.51 133250.0 -214000.0 -1.24 -1.2404 -0.9231 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N18 compound treatment 199420.0 -173000.0 -0.97 197760.0 -150000.0 -0.87 -1.3026 -0.9984 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N19 compound treatment 298690.0 -73700.0 -0.41 204320.0 -143000.0 -0.83 -0.8805 -0.9486 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N20 compound treatment 228020.0 -144000.0 -0.81 206080.0 -141000.0 -0.82 -1.1546 -1.0 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N21 compound treatment 239810.0 -133000.0 -0.75 182280.0 -165000.0 -0.96 -1.2053 -0.9924 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N22 compound treatment 361210.0 -11200.0 -0.06 300320.0 -47200.0 -0.27 -0.238 -0.8478 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N23 compound treatment 233870.0 -139000.0 -0.78 123120.0 -224000.0 -1.3 -1.4716 -0.97 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 N24 compound treatment 337800.0 -34600.0 -0.19 212000.0 -135000.0 -0.79 -0.6934 -0.8565 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O01 compound treatment 189120.0 -183000.0 -1.03 213960.0 -134000.0 -0.77 -1.2772 -0.99 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O02 compound treatment 153770.0 -219000.0 -1.23 191270.0 -156000.0 -0.91 -1.5109 -0.9886 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O03 compound treatment 88510.0 -284000.0 -1.6 80860.0 -267000.0 -1.55 -2.2235 -0.9999 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O04 compound treatment 226200.0 -146000.0 -0.82 236840.0 -111000.0 -0.64 -1.0357 -0.9924 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O05 compound treatment 187880.0 -185000.0 -1.04 297870.0 -49600.0 -0.29 -0.938 -0.8702 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O06 compound treatment 200400.0 -172000.0 -0.97 334730.0 -12800.0 -0.07 -0.737 -0.7589 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O07 compound treatment 341170.0 -31200.0 -0.18 183910.0 -164000.0 -0.95 -0.7951 -0.8241 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O08 compound treatment 140080.0 -232000.0 -1.31 252000.0 -95500.0 -0.55 -1.3164 -0.9268 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O09 compound treatment 71390.0 -301000.0 -1.69 57220.0 -290000.0 -1.68 -2.3886 -1.0 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O10 compound treatment 216610.0 -156000.0 -0.88 194850.0 -153000.0 -0.89 -1.2461 -1.0 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O11 mock treatment 325170.0 -47200.0 -0.27 442970.0 95500.0 0.55 0.2035 0.3313 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O12 mock treatment 497520.0 125000.0 0.7 400070.0 52600.0 0.3 0.7137 0.9298 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O13 compound treatment 192320.0 -180000.0 -1.01 303680.0 -43800.0 -0.25 -0.8965 -0.8578 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O14 compound treatment 209090.0 -163000.0 -0.92 244830.0 -103000.0 -0.6 -1.0711 -0.9779 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O15 compound treatment 230020.0 -142000.0 -0.8 274050.0 -73400.0 -0.43 -0.8679 -0.9562 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O16 compound treatment 354090.0 -18300.0 -0.1 232390.0 -115000.0 -0.67 -0.5449 -0.8068 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O17 compound treatment 231550.0 -141000.0 -0.79 225670.0 -122000.0 -0.71 -1.0603 -0.9983 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O18 compound treatment 213160.0 -159000.0 -0.9 239370.0 -108000.0 -0.63 -1.0773 -0.9847 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O19 compound treatment 172450.0 -200000.0 -1.13 222480.0 -125000.0 -0.72 -1.3086 -0.9774 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O20 compound treatment 267780.0 -105000.0 -0.59 279200.0 -68300.0 -0.4 -0.6965 -0.9814 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O21 compound treatment 100480.0 -272000.0 -1.53 72890.0 -275000.0 -1.59 -2.2085 -0.9998 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O22 compound treatment 249030.0 -123000.0 -0.69 142900.0 -205000.0 -1.19 -1.3301 -0.9675 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O23 compound treatment 237780.0 -135000.0 -0.76 226350.0 -121000.0 -0.7 -1.0327 -0.9993 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 O24 compound treatment 264490.0 -108000.0 -0.61 281690.0 -65800.0 -0.38 -0.6994 -0.9749 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P01 compound treatment 166940.0 -205000.0 -1.16 175680.0 -172000.0 -1.0 -1.5224 -0.9972 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P02 compound treatment 49510.0 -323000.0 -1.82 55130.0 -292000.0 -1.7 -2.4842 -0.9994 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P03 compound treatment 123000.0 -249000.0 -1.4 95300.0 -252000.0 -1.46 -2.027 -0.9998 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P04 compound treatment 37480.0 -335000.0 -1.89 33330.0 -314000.0 -1.82 -2.6215 -0.9999 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P05 compound treatment 133350.0 -239000.0 -1.35 103610.0 -244000.0 -1.41 -1.9517 -0.9997 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P06 compound treatment 111590.0 -261000.0 -1.47 115770.0 -232000.0 -1.34 -1.9885 -0.999 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P07 compound treatment 249400.0 -123000.0 -0.69 284480.0 -63000.0 -0.37 -0.748 -0.9554 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P08 compound treatment 110290.0 -262000.0 -1.48 168350.0 -179000.0 -1.04 -1.778 -0.9853 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P09 compound treatment 150280.0 -222000.0 -1.25 150640.0 -197000.0 -1.14 -1.6914 -0.999 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P10 compound treatment 128210.0 -244000.0 -1.37 149760.0 -198000.0 -1.15 -1.7829 -0.9959 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P11 mock treatment 225830.0 -147000.0 -0.83 271590.0 -75900.0 -0.44 -0.8947 -0.9567 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P12 mock treatment 300480.0 -71900.0 -0.4 310720.0 -36800.0 -0.21 -0.4371 -0.9551 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P13 compound treatment 151200.0 -221000.0 -1.25 125120.0 -222000.0 -1.29 -1.7924 -0.9998 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P14 compound treatment 217660.0 -155000.0 -0.87 296220.0 -51300.0 -0.3 -0.8262 -0.8976 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P15 compound treatment 191840.0 -181000.0 -1.02 193630.0 -154000.0 -0.89 -1.3497 -0.9979 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P16 compound treatment 214340.0 -158000.0 -0.89 238180.0 -109000.0 -0.63 -1.0775 -0.9862 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P17 compound treatment 149600.0 -223000.0 -1.25 175370.0 -172000.0 -1.0 -1.5927 -0.9936 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P18 compound treatment 152190.0 -220000.0 -1.24 155570.0 -192000.0 -1.11 -1.6636 -0.9986 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P19 compound treatment 189050.0 -183000.0 -1.03 159750.0 -188000.0 -1.09 -1.4998 -0.9996 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P20 compound treatment 188170.0 -184000.0 -1.04 119850.0 -228000.0 -1.32 -1.6669 -0.9929 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P21 compound treatment 184000.0 -188000.0 -1.06 122490.0 -225000.0 -1.3 -1.6727 -0.9947 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P22 compound treatment 299520.0 -72900.0 -0.41 224320.0 -123000.0 -0.71 -0.7952 -0.9654 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P23 compound treatment 340970.0 -31400.0 -0.18 229290.0 -118000.0 -0.69 -0.6098 -0.8614 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2093 P24 compound treatment 118440.0 -254000.0 -1.43 125000.0 -222000.0 -1.29 -1.9233 -0.9987 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A01 compound treatment 141000.0 -243000.0 -1.37 187150.0 -216000.0 -1.26 -1.8557 -0.9991 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A02 compound treatment 138330.0 -246000.0 -1.38 113790.0 -290000.0 -1.68 -2.1671 -0.9954 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A03 compound treatment 180290.0 -204000.0 -1.15 399360.0 -4230.0 -0.02 -0.829 -0.722 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A04 compound treatment 178640.0 -206000.0 -1.16 318900.0 -84700.0 -0.49 -1.1656 -0.9272 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A05 compound treatment 363310.0 -20900.0 -0.12 436980.0 33400.0 0.19 0.0538 0.2373 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A06 compound treatment 297840.0 -86400.0 -0.49 228030.0 -176000.0 -1.02 -1.0637 -0.9428 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A07 compound treatment 199960.0 -184000.0 -1.04 164600.0 -239000.0 -1.39 -1.7135 -0.9898 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A08 compound treatment 288540.0 -95700.0 -0.54 303160.0 -100000.0 -0.58 -0.7926 -0.9992 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A09 compound treatment 332960.0 -51200.0 -0.29 196160.0 -207000.0 -1.2 -1.0546 -0.8525 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A10 compound treatment 163930.0 -220000.0 -1.24 236970.0 -167000.0 -0.97 -1.5601 -0.9924 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A11 compound treatment 123760.0 -260000.0 -1.47 250580.0 -153000.0 -0.89 -1.6642 -0.9711 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A12 compound treatment 163620.0 -221000.0 -1.24 152410.0 -251000.0 -1.46 -1.9081 -0.9968 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A13 mock treatment 222240.0 -162000.0 -0.91 391900.0 -11700.0 -0.07 -0.6926 -0.7576 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A14 mock treatment 372390.0 -11800.0 -0.07 429320.0 25700.0 0.15 0.0585 0.3581 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A15 compound treatment 315260.0 -68900.0 -0.39 184960.0 -219000.0 -1.27 -1.171 -0.8831 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A16 compound treatment 205500.0 -179000.0 -1.01 214090.0 -189000.0 -1.1 -1.4884 -0.999 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A17 compound treatment 222280.0 -162000.0 -0.91 374570.0 -29000.0 -0.17 -0.7636 -0.8237 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A18 compound treatment 199490.0 -185000.0 -1.04 241690.0 -162000.0 -0.94 -1.3992 -0.9987 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A19 compound treatment 255010.0 -129000.0 -0.73 262520.0 -141000.0 -0.82 -1.0928 -0.9983 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A20 compound treatment 213970.0 -170000.0 -0.96 289700.0 -114000.0 -0.66 -1.1447 -0.9835 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A21 compound treatment 260480.0 -124000.0 -0.7 242160.0 -161000.0 -0.94 -1.1545 -0.9894 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A22 compound treatment 396900.0 12700.0 0.07 356010.0 -47600.0 -0.28 -0.1446 -0.5072 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A23 compound treatment 247000.0 -137000.0 -0.77 275840.0 -128000.0 -0.74 -1.07 -0.9998 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 A24 compound treatment 278960.0 -105000.0 -0.59 481280.0 77700.0 0.45 -0.1003 -0.1348 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B01 compound treatment 261990.0 -122000.0 -0.69 171940.0 -232000.0 -1.34 -1.4364 -0.9517 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B02 compound treatment 231120.0 -153000.0 -0.86 203090.0 -200000.0 -1.16 -1.4316 -0.9891 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B03 compound treatment 251750.0 -132000.0 -0.75 414100.0 10500.0 0.06 -0.4841 -0.6471 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B04 compound treatment 341120.0 -43100.0 -0.24 316190.0 -87400.0 -0.51 -0.5299 -0.9431 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B05 compound treatment 258570.0 -126000.0 -0.71 335780.0 -67800.0 -0.39 -0.7782 -0.9616 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B06 compound treatment 272330.0 -112000.0 -0.63 165550.0 -238000.0 -1.38 -1.4215 -0.9368 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B07 compound treatment 202880.0 -181000.0 -1.02 302200.0 -101000.0 -0.59 -1.1376 -0.9657 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B08 compound treatment 286720.0 -97500.0 -0.55 288670.0 -115000.0 -0.67 -0.8593 -0.9953 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B09 compound treatment 319730.0 -64500.0 -0.36 239550.0 -164000.0 -0.95 -0.9293 -0.9127 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B10 compound treatment 241560.0 -143000.0 -0.8 319950.0 -83600.0 -0.49 -0.9108 -0.9709 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B11 compound treatment 161650.0 -223000.0 -1.25 142580.0 -261000.0 -1.51 -1.9563 -0.9956 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B12 compound treatment 142040.0 -242000.0 -1.36 208480.0 -195000.0 -1.13 -1.7641 -0.9957 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B13 mock treatment 450170.0 66000.0 0.37 346190.0 -57400.0 -0.33 0.0272 0.0546 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B14 mock treatment 483750.0 99500.0 0.56 392060.0 -11500.0 -0.07 0.349 0.6184 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B15 compound treatment 276190.0 -108000.0 -0.61 385700.0 -17900.0 -0.1 -0.5033 -0.816 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B16 compound treatment 213990.0 -170000.0 -0.96 152320.0 -251000.0 -1.46 -1.708 -0.9793 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B17 compound treatment 281760.0 -102000.0 -0.58 311160.0 -92400.0 -0.54 -0.7868 -0.9993 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B18 compound treatment 272760.0 -111000.0 -0.63 269300.0 -134000.0 -0.78 -0.9943 -0.9943 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B19 compound treatment 231920.0 -152000.0 -0.86 357080.0 -46500.0 -0.27 -0.7969 -0.8867 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B20 compound treatment 140960.0 -243000.0 -1.37 131630.0 -272000.0 -1.58 -2.0835 -0.9975 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B21 compound treatment 307640.0 -76600.0 -0.43 343640.0 -59900.0 -0.35 -0.5506 -0.9943 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B22 compound treatment 307770.0 -76400.0 -0.43 189490.0 -214000.0 -1.24 -1.1822 -0.8997 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B23 compound treatment 271750.0 -112000.0 -0.63 304020.0 -99600.0 -0.58 -0.8559 -0.9989 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 B24 compound treatment 286310.0 -97900.0 -0.55 293920.0 -110000.0 -0.64 -0.8394 -0.9975 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C01 compound treatment 263640.0 -121000.0 -0.68 186240.0 -217000.0 -1.26 -1.3712 -0.9578 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C02 compound treatment 270850.0 -113000.0 -0.64 222960.0 -181000.0 -1.05 -1.1919 -0.9717 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C03 compound treatment 334830.0 -49400.0 -0.28 172090.0 -231000.0 -1.34 -1.1459 -0.8358 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C04 compound treatment 206110.0 -178000.0 -1.0 380160.0 -23400.0 -0.14 -0.805 -0.7957 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C05 compound treatment 159490.0 -225000.0 -1.27 251120.0 -152000.0 -0.88 -1.5197 -0.9847 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C06 compound treatment 194850.0 -189000.0 -1.07 210680.0 -193000.0 -1.12 -1.5448 -0.9997 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C07 compound treatment 408610.0 24400.0 0.14 182930.0 -221000.0 -1.28 -0.8077 -0.6276 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C08 compound treatment 390460.0 6260.0 0.04 223040.0 -181000.0 -1.05 -0.7155 -0.6829 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C09 compound treatment 397490.0 13300.0 0.07 252860.0 -151000.0 -0.87 -0.5652 -0.6442 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C10 compound treatment 202420.0 -182000.0 -1.02 85640.0 -318000.0 -1.84 -2.0275 -0.9614 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C11 mock treatment 219710.0 -164000.0 -0.93 397140.0 -6450.0 -0.04 -0.6812 -0.7351 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C12 mock treatment 303880.0 -80300.0 -0.45 422350.0 18800.0 0.11 -0.2428 -0.5221 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C13 compound treatment 291360.0 -92800.0 -0.52 368160.0 -35400.0 -0.21 -0.5149 -0.9168 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C14 compound treatment 323070.0 -61100.0 -0.34 214810.0 -189000.0 -1.09 -1.0175 -0.8866 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C15 mock treatment 324380.0 -59800.0 -0.34 257330.0 -146000.0 -0.85 -0.8379 -0.9181 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C16 mock treatment 432830.0 48600.0 0.27 295800.0 -108000.0 -0.63 -0.2484 -0.3641 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C17 compound treatment 190780.0 -193000.0 -1.09 283520.0 -120000.0 -0.7 -1.2623 -0.9767 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C18 compound treatment 258490.0 -126000.0 -0.71 210820.0 -193000.0 -1.12 -1.2909 -0.9757 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C19 compound treatment 228680.0 -156000.0 -0.88 387130.0 -16500.0 -0.1 -0.6866 -0.7796 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C20 compound treatment 210910.0 -173000.0 -0.98 193820.0 -210000.0 -1.22 -1.55 -0.994 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C21 compound treatment 237230.0 -147000.0 -0.83 240030.0 -164000.0 -0.95 -1.2558 -0.9977 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C22 compound treatment 227940.0 -156000.0 -0.88 366050.0 -37500.0 -0.22 -0.776 -0.8563 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C23 compound treatment 270800.0 -113000.0 -0.64 384590.0 -19000.0 -0.11 -0.5293 -0.8171 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 C24 compound treatment 251690.0 -133000.0 -0.75 280840.0 -123000.0 -0.71 -1.0309 -0.9997 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D01 compound treatment 320850.0 -63400.0 -0.36 156740.0 -247000.0 -1.43 -1.2645 -0.8571 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D02 compound treatment 219160.0 -165000.0 -0.93 406810.0 3220.0 0.02 -0.6438 -0.6927 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D03 compound treatment 310560.0 -73600.0 -0.41 249360.0 -154000.0 -0.89 -0.9256 -0.9389 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D04 compound treatment 175970.0 -208000.0 -1.17 303860.0 -99700.0 -0.58 -1.2379 -0.947 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D05 compound treatment 231150.0 -153000.0 -0.86 281710.0 -122000.0 -0.71 -1.109 -0.9952 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D06 compound treatment 265880.0 -118000.0 -0.67 321670.0 -81900.0 -0.48 -0.8069 -0.9863 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D07 compound treatment 245280.0 -139000.0 -0.78 180890.0 -223000.0 -1.29 -1.4662 -0.9711 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D08 compound treatment 318090.0 -66100.0 -0.37 209840.0 -194000.0 -1.12 -1.0577 -0.8936 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D09 compound treatment 191770.0 -192000.0 -1.08 370660.0 -32900.0 -0.19 -0.901 -0.8191 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D10 compound treatment 235530.0 -149000.0 -0.84 173820.0 -230000.0 -1.33 -1.534 -0.9749 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D11 mock treatment 476580.0 92400.0 0.52 448380.0 44800.0 0.26 0.5514 0.9486 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D12 mock treatment 324200.0 -60000.0 -0.34 460720.0 57100.0 0.33 -0.0046 -0.0096 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D13 compound treatment 317500.0 -66700.0 -0.38 283060.0 -121000.0 -0.7 -0.7598 -0.9575 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D14 compound treatment 270320.0 -114000.0 -0.64 285760.0 -118000.0 -0.68 -0.9365 -0.9995 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D15 mock treatment 419520.0 35300.0 0.2 394610.0 -8980.0 -0.05 0.1038 0.5049 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D16 mock treatment 456260.0 72100.0 0.41 470830.0 67200.0 0.39 0.5626 0.9998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D17 compound treatment 187300.0 -197000.0 -1.11 192960.0 -211000.0 -1.22 -1.6475 -0.9988 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D18 compound treatment 335120.0 -49100.0 -0.28 210030.0 -194000.0 -1.12 -0.9891 -0.8556 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D19 compound treatment 275100.0 -109000.0 -0.61 374340.0 -29200.0 -0.17 -0.5542 -0.8698 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D20 compound treatment 342090.0 -42100.0 -0.24 309390.0 -94200.0 -0.55 -0.5539 -0.9302 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D21 compound treatment 243680.0 -141000.0 -0.79 255040.0 -149000.0 -0.86 -1.1685 -0.9991 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D22 compound treatment 220740.0 -163000.0 -0.92 251680.0 -152000.0 -0.88 -1.2736 -0.9998 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D23 compound treatment 308840.0 -75400.0 -0.42 327040.0 -76500.0 -0.44 -0.6139 -0.9997 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 D24 compound treatment 219720.0 -164000.0 -0.93 308490.0 -95100.0 -0.55 -1.0447 -0.9694 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E01 mock treatment 457880.0 73700.0 0.41 426670.0 23100.0 0.13 0.3879 0.8901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E02 mock treatment 447040.0 62800.0 0.35 353880.0 -49700.0 -0.29 0.0463 0.1014 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E03 compound treatment 223870.0 -160000.0 -0.9 370050.0 -33500.0 -0.19 -0.7758 -0.8402 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E04 compound treatment 326310.0 -57900.0 -0.33 215120.0 -188000.0 -1.09 -1.0033 -0.8797 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E05 compound treatment 335840.0 -48400.0 -0.27 322590.0 -81000.0 -0.47 -0.5247 -0.9664 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E06 compound treatment 227440.0 -157000.0 -0.88 203100.0 -200000.0 -1.16 -1.4462 -0.9907 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E07 compound treatment 162120.0 -222000.0 -1.25 104960.0 -299000.0 -1.73 -2.1087 -0.9872 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E08 compound treatment 277670.0 -107000.0 -0.6 263360.0 -140000.0 -0.81 -0.9991 -0.9888 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E09 mock treatment 454240.0 70000.0 0.39 351880.0 -51700.0 -0.3 0.0668 0.1348 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E10 mock treatment 445820.0 61600.0 0.35 479690.0 76100.0 0.44 0.5574 0.9929 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E11 compound treatment 283850.0 -100000.0 -0.56 209890.0 -194000.0 -1.12 -1.1938 -0.9494 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E12 compound treatment 506990.0 123000.0 0.69 356640.0 -46900.0 -0.27 0.2963 0.3988 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E13 compound treatment 315870.0 -68300.0 -0.38 227360.0 -176000.0 -1.02 -0.9947 -0.9109 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E14 compound treatment 401240.0 17000.0 0.1 227290.0 -176000.0 -1.02 -0.6551 -0.638 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E15 compound treatment 243710.0 -140000.0 -0.79 436680.0 33100.0 0.19 -0.4235 -0.5204 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E16 compound treatment 399100.0 14900.0 0.08 281620.0 -122000.0 -0.71 -0.4409 -0.6189 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E17 mock treatment 358460.0 -25700.0 -0.14 437000.0 33400.0 0.19 0.0345 0.1428 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E18 mock treatment 560530.0 176000.0 0.99 357560.0 -46000.0 -0.27 0.5132 0.4992 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E19 compound treatment 431840.0 47600.0 0.27 430030.0 26400.0 0.15 0.2981 0.9648 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E20 compound treatment 236050.0 -148000.0 -0.83 238980.0 -165000.0 -0.95 -1.2648 -0.9977 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E21 compound treatment 332550.0 -51700.0 -0.29 223310.0 -180000.0 -1.05 -0.9449 -0.8707 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E22 compound treatment 322300.0 -61900.0 -0.35 252580.0 -151000.0 -0.88 -0.8657 -0.9184 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E23 compound treatment 358450.0 -25800.0 -0.14 263940.0 -140000.0 -0.81 -0.6752 -0.8206 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 E24 compound treatment 285360.0 -98800.0 -0.56 234790.0 -169000.0 -0.98 -1.0857 -0.9642 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F01 mock treatment 454560.0 70400.0 0.4 399330.0 -4260.0 -0.02 0.2626 0.6617 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F02 mock treatment 463160.0 79000.0 0.44 466970.0 63400.0 0.37 0.5742 0.9955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F03 compound treatment 211200.0 -173000.0 -0.97 194360.0 -209000.0 -1.21 -1.5467 -0.9941 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F04 compound treatment 220000.0 -164000.0 -0.92 199400.0 -204000.0 -1.18 -1.491 -0.9925 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F05 compound treatment 248640.0 -136000.0 -0.76 283160.0 -120000.0 -0.7 -1.0335 -0.999 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F06 compound treatment 251490.0 -133000.0 -0.75 172480.0 -231000.0 -1.34 -1.476 -0.9619 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F07 compound treatment 124750.0 -259000.0 -1.46 98470.0 -305000.0 -1.77 -2.284 -0.9955 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F08 compound treatment 226270.0 -158000.0 -0.89 167260.0 -236000.0 -1.37 -1.5978 -0.978 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F09 mock treatment 312920.0 -71300.0 -0.4 464320.0 60700.0 0.35 -0.0347 -0.065 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F10 mock treatment 250950.0 -133000.0 -0.75 493510.0 89900.0 0.52 -0.1617 -0.177 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F11 compound treatment 269060.0 -115000.0 -0.65 272230.0 -131000.0 -0.76 -0.997 -0.9968 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F12 compound treatment 296340.0 -87900.0 -0.49 214850.0 -189000.0 -1.09 -1.1237 -0.9356 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F13 compound treatment 363430.0 -20800.0 -0.12 386170.0 -17400.0 -0.1 -0.1541 -0.9973 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F14 compound treatment 103880.0 -280000.0 -1.58 159780.0 -244000.0 -1.41 -2.1157 -0.9985 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F15 compound treatment 223300.0 -161000.0 -0.91 180080.0 -224000.0 -1.3 -1.5571 -0.9846 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F16 compound treatment 168000.0 -216000.0 -1.22 234770.0 -169000.0 -0.98 -1.5529 -0.9942 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F17 mock treatment 430340.0 46100.0 0.26 520890.0 117000.0 0.68 0.6647 0.9128 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F18 mock treatment 402600.0 18400.0 0.1 449480.0 45900.0 0.27 0.2614 0.9154 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F19 compound treatment 217480.0 -167000.0 -0.94 228050.0 -176000.0 -1.02 -1.3835 -0.9992 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F20 compound treatment 241650.0 -143000.0 -0.8 254940.0 -149000.0 -0.86 -1.177 -0.9994 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F21 compound treatment 303760.0 -80400.0 -0.45 283770.0 -120000.0 -0.69 -0.8116 -0.9785 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F22 compound treatment 193040.0 -191000.0 -1.08 154930.0 -249000.0 -1.44 -1.7807 -0.9896 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F23 compound treatment 262930.0 -121000.0 -0.68 295940.0 -108000.0 -0.62 -0.9242 -0.999 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 F24 compound treatment 298080.0 -86100.0 -0.48 276960.0 -127000.0 -0.73 -0.8621 -0.9797 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G01 compound treatment 352000.0 -32200.0 -0.18 311450.0 -92100.0 -0.53 -0.506 -0.8968 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G02 compound treatment 271470.0 -113000.0 -0.63 468480.0 64900.0 0.38 -0.1826 -0.2475 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G03 mock treatment 448960.0 64800.0 0.36 372060.0 -31500.0 -0.18 0.1285 0.315 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G04 mock treatment 307060.0 -77100.0 -0.43 358030.0 -45600.0 -0.26 -0.4939 -0.9716 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G05 compound treatment 385980.0 1780.0 0.01 275390.0 -128000.0 -0.74 -0.5186 -0.6975 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G06 compound treatment 346830.0 -37400.0 -0.21 247270.0 -156000.0 -0.91 -0.7898 -0.8486 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G07 compound treatment 277440.0 -107000.0 -0.6 277770.0 -126000.0 -0.73 -0.9409 -0.9954 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G08 compound treatment 401950.0 17700.0 0.1 363690.0 -39900.0 -0.23 -0.093 -0.3688 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G09 compound treatment 218660.0 -166000.0 -0.93 178190.0 -225000.0 -1.31 -1.5833 -0.9862 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G10 compound treatment 227140.0 -157000.0 -0.88 280250.0 -123000.0 -0.72 -1.131 -0.9945 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G11 compound treatment 285760.0 -98400.0 -0.55 204080.0 -200000.0 -1.16 -1.21 -0.9432 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G12 compound treatment 173600.0 -211000.0 -1.19 219200.0 -184000.0 -1.07 -1.5945 -0.9987 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G13 compound treatment 498950.0 115000.0 0.65 281370.0 -122000.0 -0.71 -0.0444 -0.0463 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G14 compound treatment 298820.0 -85400.0 -0.48 151640.0 -252000.0 -1.46 -1.3731 -0.8927 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G15 compound treatment 235910.0 -148000.0 -0.83 250640.0 -153000.0 -0.89 -1.2175 -0.9995 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G16 compound treatment 268080.0 -116000.0 -0.65 255280.0 -148000.0 -0.86 -1.0704 -0.9908 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G17 compound treatment 391560.0 7360.0 0.04 401990.0 -1600.0 -0.01 0.0227 0.5356 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G18 compound treatment 235720.0 -148000.0 -0.84 258500.0 -145000.0 -0.84 -1.186 -1.0 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G19 mock treatment 330680.0 -53500.0 -0.3 345760.0 -57800.0 -0.34 -0.4502 -0.9986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G20 mock treatment 395700.0 11500.0 0.06 373560.0 -30000.0 -0.17 -0.0774 -0.4164 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G21 compound treatment 221850.0 -162000.0 -0.91 376980.0 -26600.0 -0.15 -0.7554 -0.815 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G22 compound treatment 355360.0 -28800.0 -0.16 423130.0 19500.0 0.11 -0.0347 -0.1751 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G23 compound treatment 298080.0 -86100.0 -0.48 391230.0 -12400.0 -0.07 -0.3935 -0.8029 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 G24 compound treatment 277050.0 -107000.0 -0.6 445760.0 42200.0 0.24 -0.2536 -0.3896 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H01 compound treatment 309620.0 -74600.0 -0.42 157670.0 -246000.0 -1.43 -1.3053 -0.878 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H02 compound treatment 219700.0 -165000.0 -0.93 178270.0 -225000.0 -1.31 -1.5788 -0.9858 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H03 mock treatment 311770.0 -72400.0 -0.41 277300.0 -126000.0 -0.73 -0.8062 -0.9618 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H04 mock treatment 474980.0 90800.0 0.51 362400.0 -41200.0 -0.24 0.1925 0.3412 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H05 compound treatment 352320.0 -31900.0 -0.18 270560.0 -133000.0 -0.77 -0.6724 -0.8489 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H06 compound treatment 183360.0 -201000.0 -1.13 109600.0 -294000.0 -1.7 -2.0051 -0.9801 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H07 compound treatment 187470.0 -197000.0 -1.11 227770.0 -176000.0 -1.02 -1.5041 -0.9991 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H08 compound treatment 123170.0 -261000.0 -1.47 258760.0 -145000.0 -0.84 -1.633 -0.9648 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H09 compound treatment 269190.0 -115000.0 -0.65 328980.0 -74600.0 -0.43 -0.7638 -0.9808 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H10 compound treatment 189690.0 -195000.0 -1.1 206810.0 -197000.0 -1.14 -1.5812 -0.9998 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H11 compound treatment 229290.0 -155000.0 -0.87 229020.0 -175000.0 -1.01 -1.3325 -0.9972 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H12 compound treatment 180010.0 -204000.0 -1.15 263810.0 -140000.0 -0.81 -1.386 -0.9854 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H13 compound treatment 256000.0 -128000.0 -0.72 201960.0 -202000.0 -1.17 -1.3372 -0.9731 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H14 compound treatment 318150.0 -66100.0 -0.37 167240.0 -236000.0 -1.37 -1.2321 -0.8676 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H15 compound treatment 271380.0 -113000.0 -0.64 277880.0 -126000.0 -0.73 -0.9646 -0.9976 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H16 compound treatment 352550.0 -31700.0 -0.18 279470.0 -124000.0 -0.72 -0.635 -0.8563 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H17 compound treatment 397570.0 13400.0 0.08 469720.0 66100.0 0.38 0.3244 0.83 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H18 compound treatment 315090.0 -69100.0 -0.39 309490.0 -94100.0 -0.55 -0.661 -0.9862 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H19 mock treatment 481700.0 97500.0 0.55 470810.0 67200.0 0.39 0.6638 0.986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H20 mock treatment 407310.0 23100.0 0.13 409990.0 6400.0 0.04 0.1182 0.874 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H21 compound treatment 230790.0 -153000.0 -0.86 312270.0 -91300.0 -0.53 -0.9852 -0.9724 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H22 compound treatment 266770.0 -117000.0 -0.66 286320.0 -117000.0 -0.68 -0.9484 -0.9999 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H23 compound treatment 311840.0 -72400.0 -0.41 340640.0 -62900.0 -0.37 -0.5462 -0.9985 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 H24 compound treatment 273490.0 -111000.0 -0.62 313230.0 -90400.0 -0.52 -0.8112 -0.9963 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I01 compound treatment 278520.0 -106000.0 -0.59 340760.0 -62800.0 -0.36 -0.6783 -0.9723 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I02 compound treatment 408320.0 24100.0 0.14 462270.0 58700.0 0.34 0.3367 0.9188 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I03 compound treatment 164080.0 -220000.0 -1.24 452040.0 48500.0 0.28 -0.6775 -0.5332 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I04 compound treatment 337350.0 -46900.0 -0.26 210240.0 -193000.0 -1.12 -0.9794 -0.8502 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I05 mock treatment 333060.0 -51100.0 -0.29 452390.0 48800.0 0.28 -0.0035 -0.0085 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I06 mock treatment 186750.0 -197000.0 -1.11 301180.0 -102000.0 -0.59 -1.2059 -0.9569 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I07 compound treatment 294580.0 -89600.0 -0.5 409450.0 5860.0 0.03 -0.3327 -0.658 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I08 compound treatment 324600.0 -59600.0 -0.34 439040.0 35500.0 0.21 -0.0919 -0.2335 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I09 compound treatment 382600.0 -1600.0 -0.01 383860.0 -19700.0 -0.11 -0.0873 -0.7604 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I10 compound treatment 309280.0 -74900.0 -0.42 151680.0 -252000.0 -1.46 -1.3313 -0.8755 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I11 compound treatment 270640.0 -114000.0 -0.64 282590.0 -121000.0 -0.7 -0.9482 -0.9989 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I12 compound treatment 314280.0 -69900.0 -0.39 226120.0 -177000.0 -1.03 -1.0061 -0.913 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I13 compound treatment 236340.0 -148000.0 -0.83 277120.0 -126000.0 -0.73 -1.1072 -0.998 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I14 compound treatment 365280.0 -18900.0 -0.11 332900.0 -70700.0 -0.41 -0.3652 -0.8622 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I15 compound treatment 288980.0 -95200.0 -0.54 260640.0 -143000.0 -0.83 -0.9652 -0.9777 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I16 compound treatment 205480.0 -179000.0 -1.01 304250.0 -99300.0 -0.58 -1.1188 -0.965 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I17 compound treatment 298470.0 -85700.0 -0.48 331310.0 -72300.0 -0.42 -0.6377 -0.9975 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I18 compound treatment 293660.0 -90500.0 -0.51 251560.0 -152000.0 -0.88 -0.9839 -0.9661 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I19 compound treatment 331600.0 -52600.0 -0.3 410780.0 7190.0 0.04 -0.1799 -0.6016 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I20 compound treatment 283360.0 -101000.0 -0.57 296210.0 -107000.0 -0.62 -0.8418 -0.9989 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I21 mock treatment 356000.0 -28200.0 -0.16 398240.0 -5350.0 -0.03 -0.1342 -0.8296 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I22 mock treatment 460900.0 76700.0 0.43 447360.0 43800.0 0.25 0.4848 0.9679 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I23 compound treatment 327740.0 -56500.0 -0.32 419160.0 15600.0 0.09 -0.1609 -0.4869 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 I24 compound treatment 246840.0 -137000.0 -0.77 281760.0 -122000.0 -0.71 -1.0464 -0.999 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J01 compound treatment 221020.0 -163000.0 -0.92 187650.0 -216000.0 -1.25 -1.5351 -0.9884 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J02 compound treatment 231120.0 -153000.0 -0.86 204370.0 -199000.0 -1.16 -1.4263 -0.9896 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J03 compound treatment 229680.0 -155000.0 -0.87 242580.0 -161000.0 -0.93 -1.2754 -0.9994 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J04 compound treatment 168100.0 -216000.0 -1.22 159240.0 -244000.0 -1.42 -1.8623 -0.9971 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J05 mock treatment 418510.0 34300.0 0.19 198980.0 -205000.0 -1.19 -0.7025 -0.5843 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J06 mock treatment 425700.0 41500.0 0.23 296640.0 -107000.0 -0.62 -0.2734 -0.4125 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J07 compound treatment 196380.0 -188000.0 -1.06 208200.0 -195000.0 -1.13 -1.5489 -0.9994 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J08 compound treatment 163840.0 -220000.0 -1.24 302100.0 -101000.0 -0.59 -1.2934 -0.942 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J09 compound treatment 162920.0 -221000.0 -1.25 164320.0 -239000.0 -1.39 -1.862 -0.9986 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J10 compound treatment 253610.0 -131000.0 -0.74 232800.0 -171000.0 -0.99 -1.2202 -0.9892 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J11 compound treatment 307430.0 -76800.0 -0.43 245360.0 -158000.0 -0.92 -0.9545 -0.941 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J12 compound treatment 187790.0 -196000.0 -1.11 242840.0 -161000.0 -0.93 -1.441 -0.9964 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J13 compound treatment 199000.0 -185000.0 -1.04 227220.0 -176000.0 -1.02 -1.4605 -1.0 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J14 compound treatment 290650.0 -93600.0 -0.53 318240.0 -85300.0 -0.49 -0.7224 -0.9995 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J15 compound treatment 288640.0 -95600.0 -0.54 264120.0 -139000.0 -0.81 -0.9523 -0.9804 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J16 compound treatment 309920.0 -74300.0 -0.42 297760.0 -106000.0 -0.61 -0.7297 -0.9825 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J17 compound treatment 184230.0 -200000.0 -1.13 226280.0 -177000.0 -1.03 -1.5231 -0.999 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J18 compound treatment 321600.0 -62600.0 -0.35 216960.0 -187000.0 -1.08 -1.0145 -0.8913 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J19 compound treatment 194670.0 -190000.0 -1.07 298310.0 -105000.0 -0.61 -1.1862 -0.9649 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J20 compound treatment 307680.0 -76500.0 -0.43 257130.0 -146000.0 -0.85 -0.9052 -0.9505 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J21 mock treatment 374720.0 -9480.0 -0.05 327520.0 -76100.0 -0.44 -0.3497 -0.7869 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J22 mock treatment 348240.0 -36000.0 -0.2 348390.0 -55200.0 -0.32 -0.3695 -0.9756 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J23 compound treatment 215540.0 -169000.0 -0.95 355840.0 -47700.0 -0.28 -0.8672 -0.8768 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 J24 compound treatment 205360.0 -179000.0 -1.01 226100.0 -177000.0 -1.03 -1.4398 -0.9999 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K01 compound treatment 245500.0 -139000.0 -0.78 183220.0 -220000.0 -1.28 -1.4558 -0.9721 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K02 compound treatment 370250.0 -14000.0 -0.08 413320.0 9730.0 0.06 -0.0156 -0.1616 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K03 compound treatment 242280.0 -142000.0 -0.8 208400.0 -195000.0 -1.13 -1.3654 -0.9855 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K04 compound treatment 302820.0 -81400.0 -0.46 236480.0 -167000.0 -0.97 -1.0092 -0.9415 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K05 compound treatment 168000.0 -216000.0 -1.22 226760.0 -177000.0 -1.03 -1.5858 -0.9964 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K06 compound treatment 344080.0 -40100.0 -0.23 293250.0 -110000.0 -0.64 -0.6122 -0.9021 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K07 mock treatment 393960.0 9760.0 0.05 492050.0 88500.0 0.51 0.4016 0.7784 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K08 mock treatment 264410.0 -120000.0 -0.67 299540.0 -104000.0 -0.6 -0.9035 -0.9985 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K09 compound treatment 303040.0 -81200.0 -0.46 226810.0 -177000.0 -1.03 -1.048 -0.9337 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K10 compound treatment 363270.0 -20900.0 -0.12 260320.0 -143000.0 -0.83 -0.6708 -0.7994 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K11 compound treatment 225760.0 -158000.0 -0.89 231390.0 -172000.0 -1.0 -1.3369 -0.9984 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K12 compound treatment 303600.0 -80600.0 -0.45 302980.0 -101000.0 -0.58 -0.7334 -0.9923 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K13 compound treatment 266140.0 -118000.0 -0.66 346970.0 -56600.0 -0.33 -0.7021 -0.9472 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K14 compound treatment 192230.0 -192000.0 -1.08 234530.0 -169000.0 -0.98 -1.4575 -0.9988 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K15 mock treatment 485730.0 102000.0 0.57 427100.0 23500.0 0.14 0.5006 0.8519 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K16 mock treatment 403070.0 18900.0 0.11 575370.0 172000.0 1.0 0.7796 0.7781 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K17 compound treatment 393600.0 9400.0 0.05 258980.0 -145000.0 -0.84 -0.5556 -0.6612 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K18 compound treatment 366830.0 -17400.0 -0.1 244520.0 -159000.0 -0.92 -0.7215 -0.7777 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K19 compound treatment 392120.0 7920.0 0.04 458030.0 54400.0 0.32 0.2548 0.799 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K20 compound treatment 302400.0 -81800.0 -0.46 325280.0 -78300.0 -0.45 -0.6468 -1.0 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K21 compound treatment 393760.0 9560.0 0.05 335360.0 -68200.0 -0.4 -0.2417 -0.6054 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K22 compound treatment 333620.0 -50600.0 -0.28 386130.0 -17500.0 -0.1 -0.2729 -0.9031 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K23 mock treatment 305520.0 -78700.0 -0.44 397830.0 -5760.0 -0.03 -0.3368 -0.7583 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 K24 mock treatment 351860.0 -32300.0 -0.18 432800.0 29200.0 0.17 -0.0089 -0.036 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L01 compound treatment 401920.0 17700.0 0.1 313050.0 -90500.0 -0.53 -0.3007 -0.5627 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L02 compound treatment 345460.0 -38700.0 -0.22 282900.0 -121000.0 -0.7 -0.6491 -0.8854 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L03 compound treatment 207890.0 -176000.0 -0.99 228490.0 -175000.0 -1.02 -1.4199 -0.9999 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L04 compound treatment 335960.0 -48200.0 -0.27 305160.0 -98400.0 -0.57 -0.5957 -0.9423 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L05 compound treatment 134630.0 -250000.0 -1.4 259840.0 -144000.0 -0.83 -1.5829 -0.9689 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L06 compound treatment 232170.0 -152000.0 -0.86 295630.0 -108000.0 -0.63 -1.0479 -0.9882 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L07 mock treatment 241690.0 -143000.0 -0.8 346400.0 -57200.0 -0.33 -0.8018 -0.9236 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L08 mock treatment 330170.0 -54000.0 -0.3 488290.0 84700.0 0.49 0.1323 0.2289 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L09 compound treatment 436640.0 52400.0 0.3 428200.0 24600.0 0.14 0.3097 0.9444 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L10 compound treatment 244430.0 -140000.0 -0.79 204680.0 -199000.0 -1.15 -1.3721 -0.9826 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L11 compound treatment 405480.0 21300.0 0.12 411840.0 8250.0 0.05 0.1185 0.919 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L12 compound treatment 250200.0 -134000.0 -0.75 244840.0 -159000.0 -0.92 -1.1844 -0.9951 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L13 compound treatment 323170.0 -61000.0 -0.34 432960.0 29400.0 0.17 -0.1225 -0.3194 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L14 compound treatment 219140.0 -165000.0 -0.93 291200.0 -112000.0 -0.65 -1.1179 -0.985 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L15 mock treatment 492440.0 108000.0 0.61 397320.0 -6270.0 -0.04 0.4052 0.6637 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L16 mock treatment 374600.0 -9600.0 -0.05 467200.0 63600.0 0.37 0.2226 0.5971 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L17 compound treatment 198330.0 -186000.0 -1.05 155090.0 -248000.0 -1.44 -1.7589 -0.9876 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L18 compound treatment 232330.0 -152000.0 -0.85 393490.0 -10100.0 -0.06 -0.646 -0.7538 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L19 compound treatment 293140.0 -91100.0 -0.51 509640.0 106000.0 0.62 0.0724 0.0904 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L20 compound treatment 226800.0 -157000.0 -0.89 317380.0 -86200.0 -0.5 -0.9801 -0.9633 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L21 compound treatment 323410.0 -60800.0 -0.34 336490.0 -67100.0 -0.39 -0.5171 -0.9979 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L22 compound treatment 248020.0 -136000.0 -0.77 358560.0 -45000.0 -0.26 -0.7267 -0.8973 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L23 mock treatment 416920.0 32700.0 0.18 408260.0 4670.0 0.03 0.1494 0.8025 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 L24 mock treatment 281970.0 -102000.0 -0.58 446470.0 42900.0 0.25 -0.2311 -0.3686 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M01 compound treatment 216340.0 -168000.0 -0.94 149030.0 -255000.0 -1.48 -1.7121 -0.9768 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M02 compound treatment 270530.0 -114000.0 -0.64 271410.0 -132000.0 -0.77 -0.9945 -0.996 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M03 compound treatment 379960.0 -4240.0 -0.02 181480.0 -222000.0 -1.29 -0.9277 -0.7201 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M04 compound treatment 391380.0 7180.0 0.04 432600.0 29000.0 0.17 0.1475 0.8527 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M05 compound treatment 228830.0 -155000.0 -0.87 364010.0 -39600.0 -0.23 -0.7808 -0.8634 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M06 compound treatment 446520.0 62300.0 0.35 248320.0 -155000.0 -0.9 -0.3887 -0.4022 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M07 compound treatment 155970.0 -228000.0 -1.28 146400.0 -257000.0 -1.49 -1.9632 -0.9972 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M08 compound treatment 133310.0 -251000.0 -1.41 233600.0 -170000.0 -0.99 -1.6958 -0.9845 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M09 mock treatment 419520.0 35300.0 0.2 471250.0 67700.0 0.39 0.4181 0.9504 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M10 mock treatment 353800.0 -30400.0 -0.17 531610.0 128000.0 0.74 0.404 0.5302 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M11 compound treatment 219330.0 -165000.0 -0.93 273460.0 -130000.0 -0.75 -1.1899 -0.9947 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M12 compound treatment 454920.0 70700.0 0.4 443680.0 40100.0 0.23 0.4459 0.9672 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M13 mock treatment 202400.0 -182000.0 -1.02 434360.0 30800.0 0.18 -0.5975 -0.5751 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M14 mock treatment 489670.0 105000.0 0.59 465010.0 61400.0 0.36 0.6717 0.9701 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M15 compound treatment 351780.0 -32400.0 -0.18 242900.0 -161000.0 -0.93 -0.788 -0.8298 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M16 compound treatment 405360.0 21200.0 0.12 265820.0 -138000.0 -0.8 -0.4807 -0.5951 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M17 compound treatment 280120.0 -104000.0 -0.59 196970.0 -207000.0 -1.2 -1.2616 -0.9458 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M18 compound treatment 241640.0 -143000.0 -0.8 387100.0 -16500.0 -0.1 -0.6351 -0.7858 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M19 compound treatment 329280.0 -54900.0 -0.31 305300.0 -98300.0 -0.57 -0.6217 -0.9587 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M20 compound treatment 336800.0 -47400.0 -0.27 359430.0 -44200.0 -0.26 -0.3698 -0.9998 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M21 compound treatment 282750.0 -101000.0 -0.57 320280.0 -83300.0 -0.48 -0.7455 -0.9965 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M22 compound treatment 382480.0 -1720.0 -0.01 300770.0 -103000.0 -0.6 -0.4285 -0.7185 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M23 compound treatment 244690.0 -140000.0 -0.79 416390.0 12800.0 0.07 -0.5029 -0.6374 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 M24 compound treatment 306350.0 -77900.0 -0.44 398370.0 -5220.0 -0.03 -0.3313 -0.7541 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N01 compound treatment 283220.0 -101000.0 -0.57 396850.0 -6740.0 -0.04 -0.4296 -0.7539 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N02 compound treatment 453220.0 69000.0 0.39 395200.0 -8390.0 -0.05 0.2403 0.6138 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N03 compound treatment 323760.0 -60400.0 -0.34 420820.0 17200.0 0.1 -0.1699 -0.4792 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N04 compound treatment 371480.0 -12700.0 -0.07 439070.0 35500.0 0.21 0.0949 0.4354 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N05 compound treatment 311690.0 -72500.0 -0.41 372530.0 -31100.0 -0.18 -0.416 -0.9324 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N06 compound treatment 268330.0 -116000.0 -0.65 425480.0 21900.0 0.13 -0.3715 -0.559 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N07 compound treatment 442910.0 58700.0 0.33 279360.0 -124000.0 -0.72 -0.2757 -0.3479 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N08 compound treatment 381920.0 -2280.0 -0.01 419520.0 15900.0 0.09 0.0563 0.603 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N09 mock treatment 394320.0 10100.0 0.06 480270.0 76700.0 0.44 0.3547 0.7912 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N10 mock treatment 473570.0 89400.0 0.5 416430.0 12800.0 0.07 0.4084 0.803 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N11 compound treatment 504230.0 120000.0 0.68 384120.0 -19500.0 -0.11 0.398 0.5809 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N12 compound treatment 252690.0 -132000.0 -0.74 405460.0 1870.0 0.01 -0.5158 -0.6967 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N13 mock treatment 423080.0 38900.0 0.22 459090.0 55500.0 0.32 0.3824 0.9823 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N14 mock treatment 467710.0 83500.0 0.47 309730.0 -93900.0 -0.54 -0.0525 -0.073 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N15 compound treatment 320330.0 -63900.0 -0.36 505190.0 102000.0 0.59 0.1624 0.2353 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N16 compound treatment 392890.0 8690.0 0.05 477920.0 74300.0 0.43 0.3394 0.7823 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N17 compound treatment 394920.0 10700.0 0.06 496680.0 93100.0 0.54 0.4244 0.7813 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N18 compound treatment 243680.0 -141000.0 -0.79 408710.0 5120.0 0.03 -0.5384 -0.6801 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N19 compound treatment 349370.0 -34800.0 -0.2 504580.0 101000.0 0.59 0.2755 0.446 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N20 compound treatment 249510.0 -135000.0 -0.76 300060.0 -104000.0 -0.6 -0.9607 -0.9933 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N21 compound treatment 371080.0 -13100.0 -0.07 469120.0 65500.0 0.38 0.2165 0.5592 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N22 compound treatment 267640.0 -117000.0 -0.66 309960.0 -93600.0 -0.54 -0.8479 -0.9956 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N23 compound treatment 374720.0 -9480.0 -0.05 427520.0 23900.0 0.14 0.0604 0.4062 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 N24 compound treatment 278910.0 -105000.0 -0.59 435200.0 31600.0 0.18 -0.2895 -0.4666 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O01 compound treatment 112160.0 -272000.0 -1.53 107960.0 -296000.0 -1.71 -2.2952 -0.9984 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O02 compound treatment 199000.0 -185000.0 -1.04 169950.0 -234000.0 -1.35 -1.6953 -0.9916 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O03 compound treatment 244560.0 -140000.0 -0.79 440200.0 36600.0 0.21 -0.4057 -0.4983 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O04 compound treatment 320770.0 -63400.0 -0.36 486720.0 83100.0 0.48 0.0884 0.1474 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O05 compound treatment 176520.0 -208000.0 -1.17 320370.0 -83200.0 -0.48 -1.168 -0.9234 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O06 compound treatment 198170.0 -186000.0 -1.05 326170.0 -77400.0 -0.45 -1.058 -0.9285 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O07 compound treatment 265370.0 -119000.0 -0.67 223440.0 -180000.0 -1.04 -1.2118 -0.9768 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O08 compound treatment 254680.0 -130000.0 -0.73 256250.0 -147000.0 -0.85 -1.1198 -0.9969 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O09 compound treatment 187480.0 -197000.0 -1.11 219580.0 -184000.0 -1.07 -1.5377 -0.9998 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O10 compound treatment 287950.0 -96300.0 -0.54 185120.0 -218000.0 -1.27 -1.279 -0.9282 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O11 mock treatment 467850.0 83600.0 0.47 373370.0 -30200.0 -0.18 0.2091 0.4161 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O12 mock treatment 301870.0 -82300.0 -0.46 255750.0 -148000.0 -0.86 -0.934 -0.9583 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O13 compound treatment 411880.0 27700.0 0.16 239870.0 -164000.0 -0.95 -0.5612 -0.5833 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O14 compound treatment 301690.0 -82500.0 -0.46 304500.0 -99100.0 -0.57 -0.7348 -0.9944 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O15 compound treatment 422340.0 38100.0 0.21 336020.0 -67600.0 -0.39 -0.1253 -0.2804 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O16 compound treatment 235910.0 -148000.0 -0.83 325760.0 -77800.0 -0.45 -0.9095 -0.9583 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O17 compound treatment 277730.0 -106000.0 -0.6 195460.0 -208000.0 -1.21 -1.2773 -0.9478 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O18 compound treatment 261540.0 -123000.0 -0.69 240480.0 -163000.0 -0.95 -1.1572 -0.988 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O19 compound treatment 295270.0 -88900.0 -0.5 343250.0 -60300.0 -0.35 -0.6014 -0.9847 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O20 compound treatment 350680.0 -33500.0 -0.19 245030.0 -159000.0 -0.92 -0.7837 -0.8348 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O21 compound treatment 268670.0 -116000.0 -0.65 348690.0 -54900.0 -0.32 -0.685 -0.946 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O22 compound treatment 270960.0 -113000.0 -0.64 280130.0 -123000.0 -0.72 -0.9571 -0.9983 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O23 compound treatment 316640.0 -67600.0 -0.38 395440.0 -8150.0 -0.05 -0.3024 -0.7889 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 O24 compound treatment 234030.0 -150000.0 -0.85 234960.0 -169000.0 -0.98 -1.2893 -0.9974 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P01 compound treatment 142080.0 -242000.0 -1.36 269920.0 -134000.0 -0.78 -1.512 -0.9642 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P02 compound treatment 237440.0 -147000.0 -0.83 394500.0 -9090.0 -0.05 -0.6215 -0.7507 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P03 compound treatment 368710.0 -15500.0 -0.09 190880.0 -213000.0 -1.23 -0.9339 -0.7552 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P04 compound treatment 144830.0 -239000.0 -1.35 305460.0 -98100.0 -0.57 -1.3553 -0.9265 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P05 compound treatment 168580.0 -216000.0 -1.21 204740.0 -199000.0 -1.15 -1.6738 -0.9997 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P06 compound treatment 220010.0 -164000.0 -0.92 216880.0 -187000.0 -1.08 -1.4192 -0.9969 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P07 compound treatment 152660.0 -232000.0 -1.3 224320.0 -179000.0 -1.04 -1.6568 -0.9937 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P08 compound treatment 288480.0 -95700.0 -0.54 178420.0 -225000.0 -1.31 -1.3044 -0.9234 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P09 compound treatment 302890.0 -81300.0 -0.46 311440.0 -92100.0 -0.53 -0.7016 -0.997 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P10 compound treatment 216810.0 -167000.0 -0.94 211360.0 -192000.0 -1.11 -1.4546 -0.9965 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P11 mock treatment 344650.0 -39600.0 -0.22 436280.0 32700.0 0.19 -0.0234 -0.0799 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P12 mock treatment 321630.0 -62600.0 -0.35 369490.0 -34100.0 -0.2 -0.3889 -0.9627 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P13 compound treatment 294600.0 -89600.0 -0.5 312820.0 -90800.0 -0.53 -0.7289 -0.9998 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P14 compound treatment 302110.0 -82100.0 -0.46 370570.0 -33000.0 -0.19 -0.4622 -0.9239 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P15 compound treatment 280280.0 -104000.0 -0.59 299290.0 -104000.0 -0.6 -0.8414 -0.9999 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P16 compound treatment 283840.0 -100000.0 -0.56 340340.0 -63200.0 -0.37 -0.6589 -0.9781 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P17 compound treatment 366460.0 -17700.0 -0.1 312500.0 -91100.0 -0.53 -0.4442 -0.8262 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P18 compound treatment 338730.0 -45500.0 -0.26 298910.0 -105000.0 -0.61 -0.6103 -0.9263 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P19 compound treatment 383390.0 -811.0 0.0 421180.0 17600.0 0.1 0.0689 0.6748 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P20 compound treatment 348330.0 -35900.0 -0.2 370990.0 -32600.0 -0.19 -0.2765 -0.9995 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P21 compound treatment 354930.0 -29300.0 -0.16 235070.0 -169000.0 -0.98 -0.8076 -0.8148 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P22 compound treatment 309710.0 -74500.0 -0.42 350260.0 -53300.0 -0.31 -0.5152 -0.9888 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P23 compound treatment 280890.0 -103000.0 -0.58 377070.0 -26500.0 -0.15 -0.52 -0.8644 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2094 P24 compound treatment 245290.0 -139000.0 -0.78 366050.0 -37500.0 -0.22 -0.7069 -0.8708 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A01 compound treatment 302450.0 -66100.0 -0.37 366990.0 -7370.0 -0.04 -0.2935 -0.7831 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A02 compound treatment 447520.0 78900.0 0.44 280840.0 -93500.0 -0.54 -0.0693 -0.0988 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A03 compound treatment 316360.0 -52200.0 -0.29 362290.0 -12100.0 -0.07 -0.2574 -0.8516 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A04 compound treatment 173540.0 -195000.0 -1.1 105460.0 -269000.0 -1.56 -1.8791 -0.9853 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A05 compound treatment 246240.0 -122000.0 -0.69 121620.0 -253000.0 -1.47 -1.5234 -0.9407 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A06 compound treatment 398210.0 29600.0 0.17 313970.0 -60400.0 -0.35 -0.1297 -0.3344 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A07 compound treatment 257920.0 -111000.0 -0.62 401240.0 26900.0 0.16 -0.3303 -0.5143 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A08 compound treatment 219840.0 -149000.0 -0.84 175840.0 -199000.0 -1.15 -1.4062 -0.9878 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A09 compound treatment 416590.0 48000.0 0.27 282560.0 -91800.0 -0.53 -0.1854 -0.3105 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A10 compound treatment 183730.0 -185000.0 -1.04 274720.0 -99600.0 -0.58 -1.1444 -0.9615 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A11 compound treatment 179380.0 -189000.0 -1.07 164900.0 -209000.0 -1.21 -1.6121 -0.9979 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A12 compound treatment 217870.0 -151000.0 -0.85 355920.0 -18400.0 -0.11 -0.6756 -0.79 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A13 mock treatment 289280.0 -79300.0 -0.45 271770.0 -103000.0 -0.59 -0.7364 -0.99 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A14 mock treatment 401550.0 33000.0 0.19 239140.0 -135000.0 -0.78 -0.4233 -0.5253 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A15 compound treatment 237400.0 -131000.0 -0.74 268490.0 -106000.0 -0.61 -0.9564 -0.9958 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A16 compound treatment 173490.0 -195000.0 -1.1 264130.0 -110000.0 -0.64 -1.2286 -0.9668 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A17 compound treatment 314490.0 -54100.0 -0.3 329090.0 -45300.0 -0.26 -0.401 -0.9973 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A18 compound treatment 391380.0 22800.0 0.13 290240.0 -84100.0 -0.49 -0.2542 -0.504 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A19 compound treatment 298410.0 -70200.0 -0.4 228440.0 -146000.0 -0.85 -0.8777 -0.9398 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A20 compound treatment 149720.0 -219000.0 -1.23 163360.0 -211000.0 -1.22 -1.7365 -1.0 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A21 compound treatment 202840.0 -166000.0 -0.93 132090.0 -242000.0 -1.4 -1.6533 -0.9802 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A22 compound treatment 397350.0 28800.0 0.16 251480.0 -123000.0 -0.71 -0.3894 -0.5329 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A23 compound treatment 408480.0 39900.0 0.22 346050.0 -28300.0 -0.16 0.0427 0.1536 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 A24 compound treatment 342850.0 -25700.0 -0.14 192320.0 -182000.0 -1.06 -0.8489 -0.7967 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B01 compound treatment 150080.0 -219000.0 -1.23 133080.0 -241000.0 -1.4 -1.8592 -0.9979 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B02 compound treatment 424210.0 55600.0 0.31 440380.0 66000.0 0.38 0.4922 0.995 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B03 compound treatment 450210.0 81600.0 0.46 318090.0 -56300.0 -0.33 0.0942 0.1671 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B04 compound treatment 392370.0 23800.0 0.13 343360.0 -31000.0 -0.18 -0.0324 -0.1447 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B05 compound treatment 450820.0 82200.0 0.46 424430.0 50100.0 0.29 0.5327 0.9748 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B06 compound treatment 369640.0 1050.0 0.01 332540.0 -41800.0 -0.24 -0.1673 -0.6896 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B07 compound treatment 261600.0 -107000.0 -0.6 370610.0 -3750.0 -0.02 -0.4412 -0.7321 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B08 compound treatment 170980.0 -198000.0 -1.11 164530.0 -210000.0 -1.22 -1.6471 -0.999 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B09 compound treatment 262610.0 -106000.0 -0.6 277930.0 -96400.0 -0.56 -0.8173 -0.9995 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B10 compound treatment 251650.0 -117000.0 -0.66 276490.0 -97900.0 -0.57 -0.8668 -0.9973 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B11 compound treatment 424340.0 55800.0 0.31 423770.0 49400.0 0.29 0.4246 0.999 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B12 compound treatment 252380.0 -116000.0 -0.65 275620.0 -98700.0 -0.57 -0.8675 -0.9978 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B13 mock treatment 351720.0 -16900.0 -0.09 477210.0 103000.0 0.6 0.3546 0.5871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B14 mock treatment 340210.0 -28400.0 -0.16 393240.0 18900.0 0.11 -0.0355 -0.1834 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B15 compound treatment 426310.0 57700.0 0.32 428220.0 53900.0 0.31 0.4507 0.9998 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B16 compound treatment 248110.0 -120000.0 -0.68 362750.0 -11600.0 -0.07 -0.5272 -0.7735 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B17 compound treatment 431010.0 62400.0 0.35 335040.0 -39300.0 -0.23 0.0873 0.2083 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B18 compound treatment 422460.0 53900.0 0.3 455320.0 81000.0 0.47 0.5465 0.9776 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B19 compound treatment 204510.0 -164000.0 -0.92 287590.0 -86800.0 -0.5 -1.0089 -0.9592 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B20 compound treatment 352030.0 -16600.0 -0.09 377520.0 3170.0 0.02 -0.0529 -0.5572 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B21 compound treatment 248960.0 -120000.0 -0.67 331050.0 -43300.0 -0.25 -0.6538 -0.9096 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B22 compound treatment 304320.0 -64300.0 -0.36 259070.0 -115000.0 -0.67 -0.7286 -0.9584 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B23 compound treatment 459650.0 91100.0 0.51 227310.0 -147000.0 -0.85 -0.2405 -0.2417 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 B24 compound treatment 417520.0 48900.0 0.28 200320.0 -174000.0 -1.01 -0.5189 -0.496 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C01 compound treatment 407040.0 38500.0 0.22 365400.0 -8960.0 -0.05 0.1163 0.5226 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C02 compound treatment 316720.0 -51900.0 -0.29 302800.0 -71600.0 -0.41 -0.4999 -0.9852 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C03 compound treatment 311120.0 -57500.0 -0.32 283730.0 -90600.0 -0.53 -0.6004 -0.9728 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C04 compound treatment 10890.0 -358000.0 -2.01 9210.0 -365000.0 -2.12 -2.9213 -0.9997 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C05 compound treatment 319150.0 -49400.0 -0.28 217410.0 -157000.0 -0.91 -0.8404 -0.883 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C06 compound treatment 410460.0 41900.0 0.24 339430.0 -34900.0 -0.2 0.0235 0.0755 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C07 compound treatment 309840.0 -58700.0 -0.33 366780.0 -7580.0 -0.04 -0.2649 -0.7941 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C08 compound treatment 138900.0 -230000.0 -1.29 174400.0 -200000.0 -1.16 -1.7343 -0.9985 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C09 compound treatment 364250.0 -4340.0 -0.02 349310.0 -25000.0 -0.15 -0.12 -0.8146 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C10 compound treatment 81950.0 -287000.0 -1.61 8220.0 -366000.0 -2.12 -2.6425 -0.9908 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C11 mock treatment 392920.0 24300.0 0.14 321770.0 -52600.0 -0.3 -0.1188 -0.3553 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C12 mock treatment 421280.0 52700.0 0.3 365180.0 -9180.0 -0.05 0.1721 0.5711 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C13 compound treatment 279520.0 -89100.0 -0.5 302010.0 -72300.0 -0.42 -0.6512 -0.9961 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C14 compound treatment 339420.0 -29200.0 -0.16 306820.0 -67500.0 -0.39 -0.3931 -0.9255 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C15 mock treatment 275520.0 -93100.0 -0.52 317320.0 -57000.0 -0.33 -0.6044 -0.9754 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C16 mock treatment 344550.0 -24000.0 -0.14 395440.0 21100.0 0.12 -0.0092 -0.0506 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C17 compound treatment 385290.0 16700.0 0.09 255800.0 -119000.0 -0.69 -0.4197 -0.6048 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C18 compound treatment 253560.0 -115000.0 -0.65 141970.0 -232000.0 -1.35 -1.4109 -0.9436 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C19 compound treatment 213880.0 -155000.0 -0.87 291240.0 -83100.0 -0.48 -0.9567 -0.9611 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C20 compound treatment 239170.0 -129000.0 -0.73 182240.0 -192000.0 -1.11 -1.303 -0.9788 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C21 compound treatment 218560.0 -150000.0 -0.84 217870.0 -156000.0 -0.91 -1.2389 -0.9994 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C22 compound treatment 391420.0 22800.0 0.13 290970.0 -83400.0 -0.48 -0.2511 -0.5017 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C23 compound treatment 185490.0 -183000.0 -1.03 166650.0 -208000.0 -1.2 -1.5806 -0.997 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 C24 compound treatment 358820.0 -9770.0 -0.05 249720.0 -125000.0 -0.72 -0.55 -0.7587 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D01 compound treatment 380490.0 11900.0 0.07 368670.0 -5690.0 -0.03 0.0241 0.3222 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D02 compound treatment 187520.0 -181000.0 -1.02 199420.0 -175000.0 -1.01 -1.4381 -1.0 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D03 compound treatment 379940.0 11400.0 0.06 295010.0 -79300.0 -0.46 -0.2802 -0.6031 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D04 compound treatment 400920.0 32300.0 0.18 390900.0 16500.0 0.1 0.1965 0.9553 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D05 compound treatment 373280.0 4690.0 0.03 361670.0 -12700.0 -0.07 -0.0333 -0.4266 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D06 compound treatment 176660.0 -192000.0 -1.08 190720.0 -184000.0 -1.06 -1.5171 -1.0 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D07 compound treatment 423210.0 54600.0 0.31 378250.0 3900.0 0.02 0.2334 0.757 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D08 compound treatment 333820.0 -34800.0 -0.2 321400.0 -53000.0 -0.31 -0.3556 -0.9763 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D09 compound treatment 251610.0 -117000.0 -0.66 271280.0 -103000.0 -0.6 -0.8883 -0.9988 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D10 compound treatment 169140.0 -199000.0 -1.12 177890.0 -196000.0 -1.14 -1.5996 -1.0 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D11 mock treatment 391200.0 22600.0 0.13 485600.0 111000.0 0.65 0.5462 0.8306 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D12 mock treatment 331070.0 -37500.0 -0.21 405440.0 31100.0 0.18 -0.0219 -0.0788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D13 compound treatment 350280.0 -18300.0 -0.1 290200.0 -84200.0 -0.49 -0.418 -0.838 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D14 compound treatment 438830.0 70200.0 0.4 359790.0 -14600.0 -0.08 0.2199 0.5438 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D15 mock treatment 390040.0 21500.0 0.12 377810.0 3460.0 0.02 0.0996 0.8133 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D16 mock treatment 443040.0 74500.0 0.42 316770.0 -57600.0 -0.33 0.0602 0.1124 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D17 compound treatment 282760.0 -85800.0 -0.48 292330.0 -82000.0 -0.48 -0.678 -1.0 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D18 compound treatment 212980.0 -156000.0 -0.88 266810.0 -108000.0 -0.62 -1.0604 -0.9861 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D19 compound treatment 405080.0 36500.0 0.21 278130.0 -96200.0 -0.56 -0.2493 -0.4193 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D20 compound treatment 272640.0 -95900.0 -0.54 246420.0 -128000.0 -0.74 -0.9066 -0.9878 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D21 compound treatment 244840.0 -124000.0 -0.7 428960.0 54600.0 0.32 -0.2687 -0.3511 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D22 compound treatment 158470.0 -210000.0 -1.18 159360.0 -215000.0 -1.25 -1.7181 -0.9997 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D23 compound treatment 194990.0 -174000.0 -0.98 215740.0 -159000.0 -0.92 -1.3415 -0.9995 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 D24 compound treatment 179440.0 -189000.0 -1.06 165280.0 -209000.0 -1.21 -1.6103 -0.9979 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E01 mock treatment 488680.0 120000.0 0.68 330510.0 -43800.0 -0.25 0.2982 0.4129 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E02 mock treatment 466480.0 97900.0 0.55 364690.0 -9670.0 -0.06 0.35 0.6319 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E03 compound treatment 450090.0 81500.0 0.46 320980.0 -53400.0 -0.31 0.1055 0.1907 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E04 compound treatment 396480.0 27900.0 0.16 229060.0 -145000.0 -0.84 -0.4848 -0.5656 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E05 compound treatment 446680.0 78100.0 0.44 395840.0 21500.0 0.12 0.399 0.8731 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E06 compound treatment 167040.0 -202000.0 -1.13 172120.0 -202000.0 -1.17 -1.6316 -0.9999 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E07 compound treatment 385090.0 16500.0 0.09 419880.0 45500.0 0.26 0.2524 0.9017 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E08 compound treatment 433200.0 64600.0 0.36 278400.0 -96000.0 -0.56 -0.1363 -0.205 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E09 mock treatment 359290.0 -9300.0 -0.05 347930.0 -26400.0 -0.15 -0.1454 -0.8977 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E10 mock treatment 382140.0 13600.0 0.08 443930.0 69600.0 0.4 0.3393 0.8262 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E11 compound treatment 252800.0 -116000.0 -0.65 318130.0 -56200.0 -0.33 -0.6915 -0.9487 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E12 compound treatment 301460.0 -67100.0 -0.38 309440.0 -64900.0 -0.38 -0.5334 -1.0 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E13 compound treatment 240370.0 -128000.0 -0.72 355520.0 -18800.0 -0.11 -0.5876 -0.8049 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E14 compound treatment 248180.0 -120000.0 -0.68 258810.0 -116000.0 -0.67 -0.9531 -1.0 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E15 compound treatment 185490.0 -183000.0 -1.03 167370.0 -207000.0 -1.2 -1.5777 -0.9971 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E16 compound treatment 399840.0 31300.0 0.18 273530.0 -101000.0 -0.58 -0.2891 -0.4734 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E17 mock treatment 335920.0 -32700.0 -0.18 383250.0 8900.0 0.05 -0.0936 -0.4899 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E18 mock treatment 264130.0 -104000.0 -0.59 343470.0 -30900.0 -0.18 -0.5425 -0.8825 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E19 compound treatment 165620.0 -203000.0 -1.14 316960.0 -57400.0 -0.33 -1.0433 -0.8767 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E20 compound treatment 260430.0 -108000.0 -0.61 173120.0 -201000.0 -1.17 -1.2558 -0.954 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E21 compound treatment 175240.0 -193000.0 -1.09 238480.0 -136000.0 -0.79 -1.3269 -0.9874 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E22 compound treatment 233600.0 -135000.0 -0.76 282690.0 -91700.0 -0.53 -0.9132 -0.9847 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E23 compound treatment 329840.0 -38700.0 -0.22 228700.0 -146000.0 -0.84 -0.7515 -0.8614 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 E24 compound treatment 439290.0 70700.0 0.4 417880.0 43500.0 0.25 0.4599 0.9759 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F01 mock treatment 441660.0 73100.0 0.41 465190.0 90800.0 0.53 0.6634 0.9925 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F02 mock treatment 226000.0 -143000.0 -0.8 371130.0 -3230.0 -0.02 -0.5808 -0.7234 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F03 compound treatment 307930.0 -60700.0 -0.34 287360.0 -87000.0 -0.5 -0.5982 -0.9819 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F04 compound treatment 217120.0 -151000.0 -0.85 198240.0 -176000.0 -1.02 -1.3252 -0.996 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F05 compound treatment 226580.0 -142000.0 -0.8 190050.0 -184000.0 -1.07 -1.3211 -0.9898 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F06 compound treatment 277840.0 -90700.0 -0.51 278910.0 -95400.0 -0.55 -0.7526 -0.9992 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F07 compound treatment 165400.0 -203000.0 -1.14 152480.0 -222000.0 -1.29 -1.7187 -0.9983 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F08 compound treatment 383120.0 14500.0 0.08 431200.0 56800.0 0.33 0.291 0.8566 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F09 mock treatment 451280.0 82700.0 0.47 428000.0 53600.0 0.31 0.5492 0.9808 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F10 mock treatment 393340.0 24800.0 0.14 414270.0 39900.0 0.23 0.2622 0.9705 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F11 compound treatment 378820.0 10200.0 0.06 218990.0 -155000.0 -0.9 -0.5964 -0.6606 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F12 compound treatment 155840.0 -213000.0 -1.2 196740.0 -178000.0 -1.03 -1.5752 -0.9972 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F13 compound treatment 427690.0 59100.0 0.33 357960.0 -16400.0 -0.1 0.168 0.4856 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F14 compound treatment 371520.0 2930.0 0.02 441480.0 67100.0 0.39 0.2869 0.7364 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F15 compound treatment 201150.0 -167000.0 -0.94 210330.0 -164000.0 -0.95 -1.3392 -1.0 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F16 compound treatment 277190.0 -91400.0 -0.51 274570.0 -99800.0 -0.58 -0.773 -0.9983 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F17 mock treatment 395360.0 26800.0 0.15 362690.0 -11700.0 -0.07 0.0587 0.3555 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F18 mock treatment 302510.0 -66100.0 -0.37 501190.0 127000.0 0.74 0.2571 0.3119 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F19 compound treatment 189370.0 -179000.0 -1.01 209120.0 -165000.0 -0.96 -1.391 -0.9997 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F20 compound treatment 125280.0 -243000.0 -1.37 186440.0 -188000.0 -1.09 -1.7391 -0.9936 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F21 compound treatment 224480.0 -144000.0 -0.81 198720.0 -176000.0 -1.02 -1.2939 -0.9936 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F22 compound treatment 182820.0 -186000.0 -1.05 165610.0 -209000.0 -1.21 -1.5955 -0.9973 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F23 compound treatment 272740.0 -95800.0 -0.54 267040.0 -107000.0 -0.62 -0.8216 -0.9975 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 F24 compound treatment 364390.0 -4200.0 -0.02 272260.0 -102000.0 -0.59 -0.4354 -0.7347 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G01 compound treatment 217690.0 -151000.0 -0.85 214360.0 -160000.0 -0.93 -1.2568 -0.999 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G02 compound treatment 410100.0 41500.0 0.23 436260.0 61900.0 0.36 0.4191 0.9784 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G03 mock treatment 398400.0 29800.0 0.17 433500.0 59100.0 0.34 0.3612 0.9459 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G04 mock treatment 263840.0 -105000.0 -0.59 382350.0 8000.0 0.05 -0.3842 -0.6495 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G05 compound treatment 367270.0 -1320.0 -0.01 357980.0 -16400.0 -0.09 -0.0724 -0.7601 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G06 compound treatment 389230.0 20600.0 0.12 273050.0 -101000.0 -0.59 -0.3333 -0.5565 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G07 compound treatment 379690.0 11100.0 0.06 263790.0 -111000.0 -0.64 -0.4092 -0.6352 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G08 compound treatment 329160.0 -39400.0 -0.22 349240.0 -25100.0 -0.15 -0.2599 -0.9791 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G09 compound treatment 423840.0 55300.0 0.31 196420.0 -178000.0 -1.03 -0.5097 -0.473 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G10 compound treatment 271930.0 -96700.0 -0.54 339640.0 -34700.0 -0.2 -0.5271 -0.9085 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G11 compound treatment 266880.0 -102000.0 -0.57 368980.0 -5380.0 -0.03 -0.4269 -0.7445 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G12 compound treatment 164100.0 -204000.0 -1.15 125500.0 -249000.0 -1.44 -1.8345 -0.9937 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G13 compound treatment 462830.0 94200.0 0.53 381330.0 6980.0 0.04 0.4037 0.7588 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G14 compound treatment 369250.0 661.0 0.0 223100.0 -151000.0 -0.88 -0.6176 -0.7041 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G15 compound treatment 398600.0 30000.0 0.17 425700.0 51300.0 0.3 0.33 0.964 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G16 compound treatment 262990.0 -106000.0 -0.59 239150.0 -135000.0 -0.78 -0.9748 -0.9907 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G17 compound treatment 238920.0 -130000.0 -0.73 201210.0 -173000.0 -1.0 -1.2262 -0.9877 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G18 compound treatment 162720.0 -206000.0 -1.16 136980.0 -237000.0 -1.38 -1.7929 -0.9963 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G19 mock treatment 471770.0 103000.0 0.58 404930.0 30600.0 0.18 0.5361 0.8827 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G20 mock treatment 242270.0 -126000.0 -0.71 356020.0 -18300.0 -0.11 -0.578 -0.8039 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G21 compound treatment 325340.0 -43200.0 -0.24 274780.0 -99600.0 -0.58 -0.5805 -0.9263 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G22 compound treatment 253450.0 -115000.0 -0.65 297200.0 -77200.0 -0.45 -0.7747 -0.9836 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G23 compound treatment 396010.0 27400.0 0.15 182470.0 -192000.0 -1.11 -0.6777 -0.6032 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 G24 compound treatment 303360.0 -65200.0 -0.37 313030.0 -61300.0 -0.36 -0.5111 -0.9999 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H01 compound treatment 439600.0 71000.0 0.4 155100.0 -219000.0 -1.27 -0.6164 -0.4625 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H02 compound treatment 174100.0 -194000.0 -1.09 131690.0 -243000.0 -1.41 -1.7693 -0.9923 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H03 mock treatment 428590.0 60000.0 0.34 382520.0 8170.0 0.05 0.2723 0.7984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H04 mock treatment 314560.0 -54000.0 -0.3 441480.0 67100.0 0.39 0.0602 0.1219 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H05 compound treatment 452540.0 84000.0 0.47 432530.0 58200.0 0.34 0.5727 0.9863 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H06 compound treatment 184330.0 -184000.0 -1.04 192200.0 -182000.0 -1.06 -1.4805 -1.0 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H07 compound treatment 412480.0 43900.0 0.25 351650.0 -22700.0 -0.13 0.0816 0.2915 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H08 compound treatment 428590.0 60000.0 0.34 271050.0 -103000.0 -0.6 -0.1848 -0.2687 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H09 compound treatment 375250.0 6660.0 0.04 388700.0 14300.0 0.08 0.0853 0.9352 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H10 compound treatment 178240.0 -190000.0 -1.07 304580.0 -69800.0 -0.4 -1.0438 -0.9113 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H11 compound treatment 444000.0 75400.0 0.42 258510.0 -116000.0 -0.67 -0.1749 -0.22 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H12 compound treatment 455640.0 87100.0 0.49 377930.0 3580.0 0.02 0.3612 0.7364 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H13 compound treatment 252400.0 -116000.0 -0.65 370770.0 -3590.0 -0.02 -0.4772 -0.7292 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H14 compound treatment 472980.0 104000.0 0.59 233130.0 -141000.0 -0.82 -0.1636 -0.1623 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H15 compound treatment 305690.0 -62900.0 -0.35 284480.0 -89900.0 -0.52 -0.6189 -0.9823 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H16 compound treatment 377760.0 9170.0 0.05 328640.0 -45700.0 -0.27 -0.151 -0.5589 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H17 compound treatment 207110.0 -161000.0 -0.91 186320.0 -188000.0 -1.09 -1.4139 -0.9959 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H18 compound treatment 290610.0 -78000.0 -0.44 330420.0 -43900.0 -0.25 -0.4906 -0.9665 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H19 mock treatment 324840.0 -43700.0 -0.25 351430.0 -22900.0 -0.13 -0.2682 -0.9581 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H20 mock treatment 392110.0 23500.0 0.13 302420.0 -71900.0 -0.42 -0.2014 -0.4601 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H21 compound treatment 412700.0 44100.0 0.25 314720.0 -59600.0 -0.35 -0.069 -0.162 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H22 compound treatment 135900.0 -233000.0 -1.31 130630.0 -244000.0 -1.41 -1.9257 -0.9993 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H23 compound treatment 281320.0 -87300.0 -0.49 281950.0 -92400.0 -0.54 -0.7263 -0.9991 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 H24 compound treatment 269290.0 -99300.0 -0.56 255720.0 -119000.0 -0.69 -0.8818 -0.9947 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I01 compound treatment 341780.0 -26800.0 -0.15 341600.0 -32800.0 -0.19 -0.241 -0.9935 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I02 compound treatment 326170.0 -42400.0 -0.24 408030.0 33700.0 0.2 -0.0308 -0.0997 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I03 compound treatment 393630.0 25000.0 0.14 165630.0 -209000.0 -1.21 -0.7563 -0.6206 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I04 compound treatment 487860.0 119000.0 0.67 417680.0 43300.0 0.25 0.6524 0.9101 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I05 mock treatment 466930.0 98300.0 0.55 183280.0 -191000.0 -1.11 -0.3921 -0.3165 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I06 mock treatment 416680.0 48100.0 0.27 363060.0 -11300.0 -0.07 0.1451 0.521 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I07 compound treatment 408060.0 39500.0 0.22 350340.0 -24000.0 -0.14 0.0586 0.2236 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I08 compound treatment 429520.0 60900.0 0.34 247680.0 -127000.0 -0.73 -0.2769 -0.3416 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I09 compound treatment 178150.0 -190000.0 -1.07 162170.0 -212000.0 -1.23 -1.6282 -0.9976 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I10 compound treatment 422660.0 54100.0 0.3 334750.0 -39600.0 -0.23 0.0528 0.1385 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I11 compound treatment 335610.0 -33000.0 -0.19 361950.0 -12400.0 -0.07 -0.1821 -0.9148 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I12 compound treatment 340070.0 -28500.0 -0.16 297280.0 -77100.0 -0.45 -0.4296 -0.9045 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I13 compound treatment 309870.0 -58700.0 -0.33 361250.0 -13100.0 -0.08 -0.2875 -0.8476 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I14 compound treatment 283040.0 -85500.0 -0.48 331120.0 -43200.0 -0.25 -0.5178 -0.9537 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I15 compound treatment 220120.0 -148000.0 -0.84 455840.0 81500.0 0.47 -0.2569 -0.2675 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I16 compound treatment 226120.0 -142000.0 -0.8 192030.0 -182000.0 -1.06 -1.3148 -0.9907 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I17 compound treatment 332860.0 -35700.0 -0.2 348440.0 -25900.0 -0.15 -0.2485 -0.9897 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I18 compound treatment 387400.0 18800.0 0.11 253150.0 -121000.0 -0.7 -0.4222 -0.5939 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I19 compound treatment 356710.0 -11900.0 -0.07 298570.0 -75800.0 -0.44 -0.3581 -0.8054 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I20 compound treatment 268610.0 -100000.0 -0.56 341600.0 -32800.0 -0.19 -0.5323 -0.8961 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I21 mock treatment 306910.0 -61700.0 -0.35 409960.0 35600.0 0.21 -0.0995 -0.2463 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I22 mock treatment 213180.0 -155000.0 -0.87 401280.0 26900.0 0.16 -0.5082 -0.5719 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I23 compound treatment 265870.0 -103000.0 -0.58 359330.0 -15000.0 -0.09 -0.4705 -0.8046 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 I24 compound treatment 377120.0 8530.0 0.05 232810.0 -142000.0 -0.82 -0.5465 -0.6646 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J01 compound treatment 400910.0 32300.0 0.18 325980.0 -48400.0 -0.28 -0.0697 -0.2085 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J02 compound treatment 337880.0 -30700.0 -0.17 387780.0 13400.0 0.08 -0.0672 -0.3544 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J03 compound treatment 373890.0 5300.0 0.03 153120.0 -221000.0 -1.28 -0.8861 -0.6905 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J04 compound treatment 404540.0 36000.0 0.2 288120.0 -86200.0 -0.5 -0.2105 -0.3902 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J05 mock treatment 473410.0 105000.0 0.59 382780.0 8430.0 0.05 0.4518 0.763 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J06 mock treatment 332480.0 -36100.0 -0.2 317460.0 -56900.0 -0.33 -0.3771 -0.9729 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J07 compound treatment 182110.0 -186000.0 -1.05 161950.0 -212000.0 -1.23 -1.6133 -0.9968 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J08 compound treatment 170890.0 -198000.0 -1.11 184540.0 -190000.0 -1.1 -1.5654 -1.0 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J09 compound treatment 238880.0 -130000.0 -0.73 145760.0 -229000.0 -1.33 -1.4538 -0.9605 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J10 compound treatment 287130.0 -81500.0 -0.46 303410.0 -70900.0 -0.41 -0.6152 -0.9985 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J11 compound treatment 388930.0 20300.0 0.11 259250.0 -115000.0 -0.67 -0.3911 -0.5774 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J12 compound treatment 300610.0 -68000.0 -0.38 283360.0 -91000.0 -0.53 -0.6438 -0.9875 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J13 compound treatment 161220.0 -207000.0 -1.17 72430.0 -302000.0 -1.75 -2.0636 -0.9806 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J14 compound treatment 297610.0 -71000.0 -0.4 310190.0 -64200.0 -0.37 -0.5457 -0.9994 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J15 compound treatment 461220.0 92600.0 0.52 423280.0 48900.0 0.28 0.5694 0.9591 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J16 compound treatment 155800.0 -213000.0 -1.2 141360.0 -233000.0 -1.35 -1.8025 -0.9982 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J17 compound treatment 129940.0 -239000.0 -1.34 108430.0 -266000.0 -1.54 -2.0405 -0.9976 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J18 compound treatment 356050.0 -12500.0 -0.07 229040.0 -145000.0 -0.84 -0.6458 -0.7637 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J19 compound treatment 350460.0 -18100.0 -0.1 297600.0 -76800.0 -0.45 -0.3869 -0.8472 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J20 compound treatment 358920.0 -9670.0 -0.05 318200.0 -56200.0 -0.33 -0.2688 -0.814 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J21 mock treatment 452280.0 83700.0 0.47 370400.0 -3960.0 -0.02 0.3169 0.6719 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J22 mock treatment 236330.0 -132000.0 -0.74 228520.0 -146000.0 -0.85 -1.1245 -0.998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J23 compound treatment 343860.0 -24700.0 -0.14 201510.0 -173000.0 -1.0 -0.8072 -0.7977 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 J24 compound treatment 250560.0 -118000.0 -0.66 280000.0 -94400.0 -0.55 -0.8568 -0.9954 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K01 compound treatment 199570.0 -169000.0 -0.95 188830.0 -186000.0 -1.08 -1.4336 -0.9981 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K02 compound treatment 231280.0 -137000.0 -0.77 347300.0 -27100.0 -0.16 -0.6575 -0.8336 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K03 compound treatment 370260.0 1670.0 0.01 264200.0 -110000.0 -0.64 -0.4451 -0.6966 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K04 compound treatment 222240.0 -146000.0 -0.82 170600.0 -204000.0 -1.18 -1.4181 -0.9845 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K05 compound treatment 399890.0 31300.0 0.18 304850.0 -69500.0 -0.4 -0.1604 -0.3647 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K06 compound treatment 168730.0 -200000.0 -1.13 25370.0 -349000.0 -2.02 -2.2267 -0.9616 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K07 mock treatment 387050.0 18500.0 0.1 496820.0 122000.0 0.71 0.5757 0.802 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K08 mock treatment 299210.0 -69400.0 -0.39 348320.0 -26000.0 -0.15 -0.3829 -0.9145 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K09 compound treatment 474670.0 106000.0 0.6 430500.0 56100.0 0.33 0.6525 0.9593 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K10 compound treatment 351270.0 -17300.0 -0.1 268480.0 -106000.0 -0.61 -0.5031 -0.8092 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K11 compound treatment 407380.0 38800.0 0.22 386370.0 12000.0 0.07 0.2037 0.8886 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K12 compound treatment 168320.0 -200000.0 -1.13 126930.0 -247000.0 -1.43 -1.8118 -0.9929 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K13 compound treatment 413120.0 44500.0 0.25 333440.0 -40900.0 -0.24 0.0095 0.0275 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K14 compound treatment 383740.0 15200.0 0.09 347120.0 -27200.0 -0.16 -0.0514 -0.2862 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K15 mock treatment 445310.0 76700.0 0.43 415300.0 40900.0 0.24 0.4733 0.9603 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K16 mock treatment 273380.0 -95200.0 -0.54 446500.0 72100.0 0.42 -0.0831 -0.1223 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K17 compound treatment 129760.0 -239000.0 -1.34 164000.0 -210000.0 -1.22 -1.8133 -0.9988 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K18 compound treatment 8000.0 -361000.0 -2.03 5340.0 -369000.0 -2.14 -2.9486 -0.9997 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K19 compound treatment 497290.0 129000.0 0.72 315600.0 -58800.0 -0.34 0.2714 0.3389 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K20 compound treatment 314170.0 -54400.0 -0.31 293700.0 -80700.0 -0.47 -0.5474 -0.9789 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K21 compound treatment 443680.0 75100.0 0.42 310010.0 -64300.0 -0.37 0.035 0.0622 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K22 compound treatment 308840.0 -59700.0 -0.34 290750.0 -83600.0 -0.48 -0.5807 -0.984 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K23 mock treatment 392370.0 23800.0 0.13 256700.0 -118000.0 -0.68 -0.3878 -0.5577 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 K24 mock treatment 318950.0 -49600.0 -0.28 246850.0 -128000.0 -0.74 -0.7205 -0.9114 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L01 compound treatment 393500.0 24900.0 0.14 340240.0 -34100.0 -0.2 -0.0407 -0.168 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L02 compound treatment 183720.0 -185000.0 -1.04 98400.0 -276000.0 -1.6 -1.8675 -0.9783 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L03 compound treatment 241150.0 -127000.0 -0.72 257810.0 -117000.0 -0.68 -0.9852 -0.9996 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L04 compound treatment 424320.0 55700.0 0.31 415060.0 40700.0 0.24 0.3888 0.9902 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L05 compound treatment 480670.0 112000.0 0.63 352350.0 -22000.0 -0.13 0.3559 0.5529 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L06 compound treatment 450400.0 81800.0 0.46 472640.0 98300.0 0.57 0.7287 0.9944 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L07 mock treatment 413150.0 44600.0 0.25 388660.0 14300.0 0.08 0.236 0.8934 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L08 mock treatment 400680.0 32100.0 0.18 364110.0 -10200.0 -0.06 0.0857 0.4508 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L09 compound treatment 46600.0 -322000.0 -1.81 9310.0 -365000.0 -2.12 -2.7787 -0.997 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L10 compound treatment 365150.0 -3440.0 -0.02 229800.0 -145000.0 -0.84 -0.6065 -0.7232 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L11 compound treatment 374460.0 5870.0 0.03 388480.0 14100.0 0.08 0.0813 0.9203 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L12 compound treatment 174050.0 -195000.0 -1.1 151600.0 -223000.0 -1.29 -1.6879 -0.9966 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L13 compound treatment 187300.0 -181000.0 -1.02 149230.0 -225000.0 -1.31 -1.6448 -0.9926 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L14 compound treatment 408400.0 39800.0 0.22 444390.0 70000.0 0.41 0.4457 0.9607 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L15 mock treatment 292910.0 -75700.0 -0.43 384440.0 10100.0 0.06 -0.2599 -0.6044 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L16 mock treatment 470570.0 102000.0 0.57 355220.0 -19100.0 -0.11 0.3275 0.5601 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L17 compound treatment 437080.0 68500.0 0.39 356800.0 -17600.0 -0.1 0.2007 0.5032 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L18 compound treatment 149760.0 -219000.0 -1.23 191680.0 -183000.0 -1.06 -1.6202 -0.9972 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L19 compound treatment 255790.0 -113000.0 -0.64 315680.0 -58700.0 -0.34 -0.6896 -0.9572 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L20 compound treatment 344520.0 -24100.0 -0.14 232530.0 -142000.0 -0.82 -0.6774 -0.8126 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L21 compound treatment 320830.0 -47800.0 -0.27 210300.0 -164000.0 -0.95 -0.8629 -0.8727 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L22 compound treatment 339240.0 -29300.0 -0.17 382810.0 8460.0 0.05 -0.0822 -0.4767 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L23 mock treatment 219680.0 -149000.0 -0.84 307930.0 -66400.0 -0.39 -0.8652 -0.9378 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 L24 mock treatment 325240.0 -43300.0 -0.24 308730.0 -65600.0 -0.38 -0.4417 -0.9769 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M01 compound treatment 339780.0 -28800.0 -0.16 339040.0 -35300.0 -0.2 -0.2595 -0.9933 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M02 compound treatment 445970.0 77400.0 0.44 418200.0 43800.0 0.25 0.4878 0.9671 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M03 compound treatment 415000.0 46400.0 0.26 326720.0 -47600.0 -0.28 -0.0106 -0.0279 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M04 compound treatment 418320.0 49700.0 0.28 415680.0 41300.0 0.24 0.3674 0.997 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M05 compound treatment 150560.0 -218000.0 -1.23 97630.0 -277000.0 -1.6 -2.0027 -0.9912 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M06 compound treatment 420530.0 51900.0 0.29 261010.0 -113000.0 -0.66 -0.258 -0.3587 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M07 compound treatment 367750.0 -839.0 0.0 387560.0 13200.0 0.08 0.0508 0.6623 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M08 compound treatment 262400.0 -106000.0 -0.6 332220.0 -42100.0 -0.24 -0.5955 -0.9221 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M09 mock treatment 403940.0 35400.0 0.2 385360.0 11000.0 0.06 0.1859 0.8893 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M10 mock treatment 456640.0 88100.0 0.5 441840.0 67500.0 0.39 0.6272 0.9932 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M11 compound treatment 235880.0 -133000.0 -0.75 244880.0 -129000.0 -0.75 -1.0592 -1.0 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M12 compound treatment 34300.0 -334000.0 -1.88 6620.0 -368000.0 -2.13 -2.8387 -0.9981 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M13 mock treatment 425010.0 56400.0 0.32 451480.0 77100.0 0.45 0.5409 0.9859 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M14 mock treatment 309070.0 -59500.0 -0.34 465950.0 91600.0 0.53 0.1387 0.2208 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M15 compound treatment 367040.0 -1550.0 -0.01 368240.0 -6120.0 -0.04 -0.0312 -0.8555 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M16 compound treatment 338270.0 -30300.0 -0.17 399170.0 24800.0 0.14 -0.0189 -0.0848 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M17 compound treatment 425890.0 57300.0 0.32 456060.0 81700.0 0.47 0.5632 0.9824 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M18 compound treatment 318130.0 -50500.0 -0.28 324030.0 -50300.0 -0.29 -0.4072 -0.9999 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M19 compound treatment 400860.0 32300.0 0.18 285710.0 -88600.0 -0.51 -0.2351 -0.4311 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M20 compound treatment 210610.0 -158000.0 -0.89 341170.0 -33200.0 -0.19 -0.7649 -0.8407 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M21 compound treatment 229390.0 -139000.0 -0.78 250250.0 -124000.0 -0.72 -1.063 -0.9991 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M22 compound treatment 206720.0 -162000.0 -0.91 366800.0 -7560.0 -0.04 -0.6753 -0.7403 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M23 compound treatment 350750.0 -17800.0 -0.1 285280.0 -89100.0 -0.52 -0.4363 -0.829 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 M24 compound treatment 224110.0 -144000.0 -0.81 288760.0 -85600.0 -0.5 -0.9261 -0.9719 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N01 compound treatment 274310.0 -94300.0 -0.53 465150.0 90800.0 0.53 -0.003 -0.004 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N02 compound treatment 396710.0 28100.0 0.16 395420.0 21100.0 0.12 0.1983 0.9918 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N03 compound treatment 460640.0 92100.0 0.52 356800.0 -17600.0 -0.1 0.2944 0.5575 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N04 compound treatment 276320.0 -92300.0 -0.52 267220.0 -107000.0 -0.62 -0.8066 -0.996 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N05 compound treatment 416130.0 47500.0 0.27 307880.0 -66500.0 -0.39 -0.0834 -0.1776 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N06 compound treatment 170300.0 -198000.0 -1.12 138000.0 -236000.0 -1.37 -1.7586 -0.9948 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N07 compound treatment 369140.0 551.0 0.0 336480.0 -37900.0 -0.22 -0.1531 -0.697 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N08 compound treatment 383370.0 14800.0 0.08 369520.0 -4840.0 -0.03 0.039 0.4443 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N09 mock treatment 431840.0 63300.0 0.36 340020.0 -34300.0 -0.2 0.111 0.272 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N10 mock treatment 453830.0 85200.0 0.48 393170.0 18800.0 0.11 0.4165 0.8463 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N11 compound treatment 321280.0 -47300.0 -0.27 347760.0 -26600.0 -0.15 -0.2974 -0.9663 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N12 compound treatment 166500.0 -202000.0 -1.14 167060.0 -207000.0 -1.2 -1.6545 -0.9996 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N13 mock treatment 440450.0 71900.0 0.4 427040.0 52700.0 0.31 0.5021 0.9904 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N14 mock treatment 443710.0 75100.0 0.42 480290.0 106000.0 0.61 0.7335 0.9834 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N15 compound treatment 143260.0 -225000.0 -1.27 169860.0 -204000.0 -1.19 -1.7356 -0.9994 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N16 compound treatment 295850.0 -72700.0 -0.41 294310.0 -80000.0 -0.46 -0.6178 -0.998 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N17 compound treatment 267070.0 -102000.0 -0.57 419010.0 44700.0 0.26 -0.221 -0.3522 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N18 compound treatment 220280.0 -148000.0 -0.83 212230.0 -162000.0 -0.94 -1.2552 -0.9982 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N19 compound treatment 347550.0 -21000.0 -0.12 343300.0 -31100.0 -0.18 -0.2111 -0.9793 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N20 compound treatment 226730.0 -142000.0 -0.8 214690.0 -160000.0 -0.93 -1.2194 -0.9973 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N21 compound treatment 259580.0 -109000.0 -0.61 275040.0 -99300.0 -0.58 -0.8412 -0.9995 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N22 compound treatment 304070.0 -64500.0 -0.36 220690.0 -154000.0 -0.89 -0.887 -0.9217 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N23 compound treatment 325570.0 -43000.0 -0.24 236000.0 -138000.0 -0.8 -0.7386 -0.8813 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 N24 compound treatment 280120.0 -88500.0 -0.5 227450.0 -147000.0 -0.85 -0.9546 -0.9673 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O01 compound treatment 262240.0 -106000.0 -0.6 208110.0 -166000.0 -0.96 -1.1051 -0.9737 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O02 compound treatment 219390.0 -149000.0 -0.84 154250.0 -220000.0 -1.28 -1.4965 -0.9794 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O03 compound treatment 470210.0 102000.0 0.57 419600.0 45200.0 0.26 0.5901 0.9375 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O04 compound treatment 406080.0 37500.0 0.21 323970.0 -50400.0 -0.29 -0.0574 -0.1592 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O05 compound treatment 407300.0 38700.0 0.22 303040.0 -71300.0 -0.41 -0.1384 -0.2959 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O06 compound treatment 372970.0 4380.0 0.02 303880.0 -70500.0 -0.41 -0.2716 -0.6632 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O07 compound treatment 331040.0 -37500.0 -0.21 347550.0 -26800.0 -0.16 -0.2594 -0.9886 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O08 compound treatment 372490.0 3900.0 0.02 344350.0 -30000.0 -0.17 -0.1075 -0.613 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O09 compound treatment 343840.0 -24700.0 -0.14 413720.0 39400.0 0.23 0.0629 0.2352 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O10 compound treatment 448600.0 80000.0 0.45 358970.0 -15400.0 -0.09 0.2554 0.5562 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O11 mock treatment 459040.0 90500.0 0.51 440850.0 66500.0 0.39 0.6327 0.9906 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O12 mock treatment 381600.0 13000.0 0.07 480640.0 106000.0 0.62 0.4876 0.7856 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O13 compound treatment 341000.0 -27600.0 -0.16 396560.0 22200.0 0.13 -0.0188 -0.093 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O14 compound treatment 353560.0 -15000.0 -0.08 451970.0 77600.0 0.45 0.2585 0.5643 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O15 compound treatment 169890.0 -199000.0 -1.12 184000.0 -190000.0 -1.1 -1.5716 -1.0 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O16 compound treatment 365160.0 -3430.0 -0.02 332350.0 -42000.0 -0.24 -0.1859 -0.7607 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O17 compound treatment 339690.0 -28900.0 -0.16 296810.0 -77500.0 -0.45 -0.433 -0.9055 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O18 compound treatment 319470.0 -49100.0 -0.28 328760.0 -45600.0 -0.26 -0.3825 -0.9998 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O19 compound treatment 388480.0 19900.0 0.11 370510.0 -3850.0 -0.02 0.0634 0.5554 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O20 compound treatment 271080.0 -97500.0 -0.55 283310.0 -91000.0 -0.53 -0.7615 -0.9998 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O21 compound treatment 388030.0 19400.0 0.11 257190.0 -117000.0 -0.68 -0.4031 -0.5857 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O22 compound treatment 409760.0 41200.0 0.23 297040.0 -77300.0 -0.45 -0.1532 -0.3034 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O23 compound treatment 307760.0 -60800.0 -0.34 372870.0 -1490.0 -0.01 -0.2482 -0.7247 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 O24 compound treatment 281600.0 -87000.0 -0.49 284060.0 -90300.0 -0.52 -0.7166 -0.9994 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P01 compound treatment 315240.0 -53300.0 -0.3 260290.0 -114000.0 -0.66 -0.6801 -0.9362 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P02 compound treatment 248100.0 -120000.0 -0.68 325500.0 -48900.0 -0.28 -0.68 -0.925 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P03 compound treatment 240280.0 -128000.0 -0.72 172060.0 -202000.0 -1.17 -1.3403 -0.9729 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P04 compound treatment 274900.0 -93700.0 -0.53 174570.0 -200000.0 -1.16 -1.1922 -0.9365 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P05 compound treatment 137880.0 -231000.0 -1.3 136720.0 -238000.0 -1.38 -1.8929 -0.9996 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P06 compound treatment 285200.0 -83400.0 -0.47 248800.0 -126000.0 -0.73 -0.8468 -0.9775 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P07 compound treatment 271250.0 -97300.0 -0.55 346240.0 -28100.0 -0.16 -0.5028 -0.8794 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P08 compound treatment 311250.0 -57300.0 -0.32 376350.0 2000.0 0.01 -0.2201 -0.6813 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P09 compound treatment 282580.0 -86000.0 -0.48 278910.0 -95400.0 -0.55 -0.7338 -0.9978 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P10 compound treatment 235700.0 -133000.0 -0.75 201120.0 -173000.0 -1.0 -1.2394 -0.9895 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P11 mock treatment 306210.0 -62400.0 -0.35 254330.0 -120000.0 -0.7 -0.7405 -0.9498 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P12 mock treatment 226080.0 -143000.0 -0.8 243840.0 -131000.0 -0.76 -1.1025 -0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P13 compound treatment 296110.0 -72500.0 -0.41 292910.0 -81400.0 -0.47 -0.6225 -0.9973 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P14 compound treatment 166680.0 -202000.0 -1.14 179530.0 -195000.0 -1.13 -1.6027 -1.0 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P15 compound treatment 213160.0 -155000.0 -0.87 257480.0 -117000.0 -0.68 -1.098 -0.992 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P16 compound treatment 332240.0 -36300.0 -0.2 337300.0 -37100.0 -0.21 -0.2966 -0.9997 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P17 compound treatment 223360.0 -145000.0 -0.82 268250.0 -106000.0 -0.62 -1.0132 -0.9902 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P18 compound treatment 232490.0 -136000.0 -0.77 266210.0 -108000.0 -0.63 -0.9852 -0.9951 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P19 compound treatment 180000.0 -189000.0 -1.06 152160.0 -222000.0 -1.29 -1.6619 -0.9954 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P20 compound treatment 131730.0 -237000.0 -1.33 101760.0 -273000.0 -1.58 -2.0607 -0.9964 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P21 compound treatment 142770.0 -226000.0 -1.27 129760.0 -245000.0 -1.42 -1.9019 -0.9985 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P22 compound treatment 100230.0 -268000.0 -1.51 107960.0 -266000.0 -1.54 -2.1607 -0.9999 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P23 compound treatment 372250.0 3660.0 0.02 181300.0 -193000.0 -1.12 -0.7771 -0.694 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2095 P24 compound treatment 148180.0 -220000.0 -1.24 125830.0 -249000.0 -1.44 -1.8965 -0.9972 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A01 compound treatment 264030.0 -101000.0 -0.57 388830.0 41400.0 0.24 -0.2324 -0.3765 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A02 compound treatment 371760.0 6700.0 0.04 416320.0 68900.0 0.4 0.3091 0.7704 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A03 compound treatment 137660.0 -227000.0 -1.28 169760.0 -178000.0 -1.03 -1.6338 -0.9942 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A04 compound treatment 276860.0 -88200.0 -0.5 359590.0 12100.0 0.07 -0.3013 -0.6008 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A05 compound treatment 410190.0 45100.0 0.25 219880.0 -128000.0 -0.74 -0.3435 -0.4391 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A06 compound treatment 170080.0 -195000.0 -1.1 147200.0 -200000.0 -1.16 -1.5973 -0.9996 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A07 compound treatment 120490.0 -245000.0 -1.38 168020.0 -179000.0 -1.04 -1.7093 -0.9905 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A08 compound treatment 294760.0 -70300.0 -0.4 231200.0 -116000.0 -0.67 -0.7565 -0.9678 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A09 compound treatment 178410.0 -187000.0 -1.05 332960.0 -14500.0 -0.08 -0.8024 -0.7612 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A10 compound treatment 254530.0 -111000.0 -0.62 333030.0 -14400.0 -0.08 -0.4991 -0.7949 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A11 compound treatment 326720.0 -38300.0 -0.22 303360.0 -44100.0 -0.26 -0.3334 -0.9965 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A12 compound treatment 330620.0 -34400.0 -0.19 239250.0 -108000.0 -0.63 -0.5808 -0.8843 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A13 mock treatment 268810.0 -96300.0 -0.54 352020.0 4580.0 0.03 -0.3644 -0.6717 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A14 mock treatment 235010.0 -130000.0 -0.73 337540.0 -9900.0 -0.06 -0.5583 -0.7602 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A15 compound treatment 346450.0 -18600.0 -0.1 350350.0 2910.0 0.02 -0.0622 -0.5857 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A16 compound treatment 123940.0 -241000.0 -1.36 133820.0 -214000.0 -1.24 -1.8358 -0.999 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A17 compound treatment 366050.0 989.0 0.01 295680.0 -51800.0 -0.3 -0.2083 -0.6939 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A18 compound treatment 127700.0 -237000.0 -1.34 112610.0 -235000.0 -1.36 -1.9079 -1.0 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A19 compound treatment 292540.0 -72500.0 -0.41 312960.0 -34500.0 -0.2 -0.4301 -0.9461 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A20 compound treatment 261990.0 -103000.0 -0.58 199330.0 -148000.0 -0.86 -1.0177 -0.9818 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A21 compound treatment 270160.0 -94900.0 -0.53 337470.0 -9970.0 -0.06 -0.4187 -0.7791 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A22 compound treatment 367550.0 2490.0 0.01 276710.0 -70700.0 -0.41 -0.2802 -0.6826 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A23 compound treatment 278980.0 -86100.0 -0.48 384600.0 37200.0 0.22 -0.1903 -0.3588 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 A24 compound treatment 159930.0 -205000.0 -1.15 301670.0 -45800.0 -0.27 -1.0043 -0.8475 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B01 compound treatment 401760.0 36700.0 0.21 426130.0 78700.0 0.46 0.4688 0.9358 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B02 compound treatment 304080.0 -61000.0 -0.34 430190.0 82700.0 0.48 0.0966 0.1637 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B03 compound treatment 322930.0 -42100.0 -0.24 210170.0 -137000.0 -0.8 -0.7306 -0.8796 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B04 compound treatment 360370.0 -4690.0 -0.03 371720.0 24300.0 0.14 0.0809 0.5646 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B05 compound treatment 413290.0 48200.0 0.27 261930.0 -85500.0 -0.5 -0.1587 -0.2807 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B06 compound treatment 380920.0 15900.0 0.09 379390.0 31900.0 0.19 0.1941 0.944 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B07 compound treatment 361200.0 -3860.0 -0.02 371150.0 23700.0 0.14 0.0819 0.588 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B08 compound treatment 430510.0 65400.0 0.37 343440.0 -4000.0 -0.02 0.2441 0.6613 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B09 compound treatment 395000.0 29900.0 0.17 384060.0 36600.0 0.21 0.2693 0.9934 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B10 compound treatment 433560.0 68500.0 0.39 338830.0 -8610.0 -0.05 0.2374 0.6104 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B11 compound treatment 275150.0 -89900.0 -0.51 233760.0 -114000.0 -0.66 -0.8241 -0.9915 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B12 compound treatment 306310.0 -58800.0 -0.33 291120.0 -56300.0 -0.33 -0.4648 -1.0 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B13 mock treatment 455750.0 90700.0 0.51 478840.0 131000.0 0.76 0.8998 0.981 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B14 mock treatment 380750.0 15700.0 0.09 385060.0 37600.0 0.22 0.2167 0.9208 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B15 compound treatment 296580.0 -68500.0 -0.39 284740.0 -62700.0 -0.36 -0.5297 -0.9996 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B16 compound treatment 328930.0 -36100.0 -0.2 269640.0 -77800.0 -0.45 -0.4629 -0.9352 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B17 compound treatment 400520.0 35500.0 0.2 261680.0 -85800.0 -0.5 -0.2105 -0.3929 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B18 compound treatment 178260.0 -187000.0 -1.05 158900.0 -189000.0 -1.09 -1.5168 -0.9998 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B19 compound treatment 317130.0 -47900.0 -0.27 446590.0 99100.0 0.58 0.2158 0.3397 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B20 compound treatment 159530.0 -206000.0 -1.16 156960.0 -190000.0 -1.1 -1.5993 -0.9997 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B21 compound treatment 230830.0 -134000.0 -0.76 366690.0 19200.0 0.11 -0.4554 -0.5962 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B22 compound treatment 212990.0 -152000.0 -0.86 312190.0 -35300.0 -0.2 -0.7499 -0.852 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B23 compound treatment 252000.0 -113000.0 -0.64 290720.0 -56700.0 -0.33 -0.6827 -0.9528 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 B24 compound treatment 195380.0 -170000.0 -0.96 209390.0 -138000.0 -0.8 -1.2416 -0.9961 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C01 compound treatment 408540.0 43500.0 0.24 378200.0 30800.0 0.18 0.2992 0.9879 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C02 compound treatment 252800.0 -112000.0 -0.63 339950.0 -7490.0 -0.04 -0.4776 -0.7539 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C03 compound treatment 209070.0 -156000.0 -0.88 253200.0 -94200.0 -0.55 -1.0074 -0.974 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C04 compound treatment 140320.0 -225000.0 -1.27 142560.0 -205000.0 -1.19 -1.7348 -0.9995 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C05 compound treatment 155800.0 -209000.0 -1.18 117500.0 -230000.0 -1.33 -1.7759 -0.9981 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C06 compound treatment 263000.0 -102000.0 -0.57 294180.0 -53300.0 -0.31 -0.6247 -0.9576 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C07 compound treatment 160080.0 -205000.0 -1.15 158560.0 -189000.0 -1.1 -1.5905 -0.9997 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C08 compound treatment 327840.0 -37200.0 -0.21 361320.0 13900.0 0.08 -0.0913 -0.4065 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C09 compound treatment 150420.0 -215000.0 -1.21 171870.0 -176000.0 -1.02 -1.5744 -0.9964 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C10 compound treatment 366890.0 1830.0 0.01 351490.0 4050.0 0.02 0.0239 0.9316 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C11 mock treatment 179320.0 -186000.0 -1.05 260040.0 -87400.0 -0.51 -1.0978 -0.9447 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C12 mock treatment 413050.0 48000.0 0.27 401360.0 53900.0 0.31 0.4121 0.9973 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C13 compound treatment 314740.0 -50300.0 -0.28 185770.0 -162000.0 -0.94 -0.8633 -0.8814 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C14 compound treatment 409830.0 44800.0 0.25 219710.0 -128000.0 -0.74 -0.3456 -0.4417 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C15 mock treatment 280640.0 -84400.0 -0.48 232400.0 -115000.0 -0.67 -0.8078 -0.9862 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C16 mock treatment 287840.0 -77200.0 -0.43 338780.0 -8660.0 -0.05 -0.3429 -0.7836 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C17 compound treatment 267520.0 -97500.0 -0.55 253120.0 -94300.0 -0.55 -0.7751 -1.0 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C18 compound treatment 270980.0 -94100.0 -0.53 218430.0 -129000.0 -0.75 -0.9036 -0.9857 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C19 compound treatment 346760.0 -18300.0 -0.1 191630.0 -156000.0 -0.9 -0.7118 -0.7827 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C20 compound treatment 288480.0 -76600.0 -0.43 149920.0 -198000.0 -1.15 -1.1148 -0.9109 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C21 compound treatment 253730.0 -111000.0 -0.63 168400.0 -179000.0 -1.04 -1.1774 -0.9708 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C22 compound treatment 328530.0 -36500.0 -0.21 333170.0 -14300.0 -0.08 -0.2039 -0.92 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C23 compound treatment 112060.0 -253000.0 -1.42 133930.0 -214000.0 -1.24 -1.8827 -0.9976 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 C24 compound treatment 190480.0 -175000.0 -0.98 261370.0 -86100.0 -0.5 -1.0479 -0.9507 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D01 compound treatment 349160.0 -15900.0 -0.09 371750.0 24300.0 0.14 0.0364 0.2179 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D02 compound treatment 112390.0 -253000.0 -1.42 217360.0 -130000.0 -0.75 -1.5392 -0.956 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D03 compound treatment 198140.0 -167000.0 -0.94 318150.0 -29300.0 -0.17 -0.7846 -0.8216 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D04 compound treatment 351640.0 -13400.0 -0.08 299230.0 -48200.0 -0.28 -0.2511 -0.8671 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D05 compound treatment 219710.0 -145000.0 -0.82 223630.0 -124000.0 -0.72 -1.0863 -0.9979 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D06 compound treatment 373530.0 8470.0 0.05 361810.0 14400.0 0.08 0.0926 0.9649 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D07 compound treatment 432480.0 67400.0 0.38 297450.0 -50000.0 -0.29 0.0634 0.1327 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D08 compound treatment 257600.0 -107000.0 -0.6 231050.0 -116000.0 -0.68 -0.9051 -0.9985 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D09 compound treatment 164320.0 -201000.0 -1.13 157120.0 -190000.0 -1.1 -1.5796 -0.9999 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D10 compound treatment 295840.0 -69200.0 -0.39 342080.0 -5360.0 -0.03 -0.2975 -0.7611 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D11 mock treatment 385980.0 20900.0 0.12 393920.0 46500.0 0.27 0.2739 0.9311 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D12 mock treatment 330500.0 -34600.0 -0.19 263740.0 -83700.0 -0.49 -0.4808 -0.9194 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D13 compound treatment 275740.0 -89300.0 -0.5 232000.0 -115000.0 -0.67 -0.829 -0.99 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D14 compound treatment 385890.0 20800.0 0.12 293920.0 -53500.0 -0.31 -0.1366 -0.4116 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D15 mock treatment 389990.0 24900.0 0.14 326120.0 -21300.0 -0.12 0.0118 0.0631 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D16 mock treatment 246400.0 -119000.0 -0.67 232640.0 -115000.0 -0.67 -0.9431 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D17 compound treatment 243840.0 -121000.0 -0.68 365560.0 18100.0 0.11 -0.4082 -0.5913 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D18 compound treatment 304670.0 -60400.0 -0.34 249130.0 -98300.0 -0.57 -0.6436 -0.9695 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D19 compound treatment 297600.0 -67500.0 -0.38 255480.0 -92000.0 -0.53 -0.6457 -0.9862 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D20 compound treatment 361860.0 -3200.0 -0.02 341050.0 -6390.0 -0.04 -0.039 -0.9451 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D21 compound treatment 286620.0 -78400.0 -0.44 284040.0 -63400.0 -0.37 -0.5722 -0.9959 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D22 compound treatment 310560.0 -54500.0 -0.31 224190.0 -123000.0 -0.71 -0.7224 -0.9287 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D23 compound treatment 218900.0 -146000.0 -0.82 319330.0 -28100.0 -0.16 -0.6971 -0.8311 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 D24 compound treatment 203240.0 -162000.0 -0.91 186100.0 -161000.0 -0.94 -1.3058 -0.9999 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E01 mock treatment 318340.0 -46700.0 -0.26 435640.0 88200.0 0.51 0.1757 0.3055 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E02 mock treatment 395200.0 30100.0 0.17 388720.0 41300.0 0.24 0.2892 0.9858 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E03 compound treatment 155730.0 -209000.0 -1.18 126340.0 -221000.0 -1.28 -1.74 -0.9991 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E04 compound treatment 151600.0 -213000.0 -1.2 151440.0 -196000.0 -1.14 -1.6535 -0.9996 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E05 compound treatment 367840.0 2780.0 0.02 260600.0 -86800.0 -0.5 -0.3451 -0.6848 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E06 compound treatment 311650.0 -53400.0 -0.3 305300.0 -42100.0 -0.24 -0.3854 -0.9947 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E07 compound treatment 342370.0 -22700.0 -0.13 234470.0 -113000.0 -0.66 -0.5536 -0.8294 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E08 compound treatment 426080.0 61000.0 0.34 270970.0 -76500.0 -0.44 -0.0707 -0.126 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E09 mock treatment 317120.0 -47900.0 -0.27 418010.0 70600.0 0.41 0.0985 0.201 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E10 mock treatment 414880.0 49800.0 0.28 421670.0 74200.0 0.43 0.5027 0.9785 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E11 compound treatment 191250.0 -174000.0 -0.98 136200.0 -211000.0 -1.23 -1.5581 -0.9938 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E12 compound treatment 439490.0 74400.0 0.42 395850.0 48400.0 0.28 0.4948 0.981 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E13 compound treatment 114200.0 -251000.0 -1.41 160480.0 -187000.0 -1.08 -1.7653 -0.9915 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E14 compound treatment 414690.0 49600.0 0.28 354300.0 6860.0 0.04 0.2257 0.7997 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E15 compound treatment 322480.0 -42600.0 -0.24 298010.0 -49400.0 -0.29 -0.3722 -0.996 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E16 compound treatment 279430.0 -85600.0 -0.48 437700.0 90300.0 0.52 0.0293 0.0411 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E17 mock treatment 312060.0 -53000.0 -0.3 376770.0 29300.0 0.17 -0.0907 -0.2641 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E18 mock treatment 381600.0 16500.0 0.09 294400.0 -53000.0 -0.31 -0.1517 -0.4719 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E19 compound treatment 183960.0 -181000.0 -1.02 180240.0 -167000.0 -0.97 -1.4066 -0.9997 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E20 compound treatment 268370.0 -96700.0 -0.54 384640.0 37200.0 0.22 -0.2324 -0.3968 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E21 compound treatment 139880.0 -225000.0 -1.27 157870.0 -190000.0 -1.1 -1.6738 -0.9975 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E22 compound treatment 138190.0 -227000.0 -1.28 144220.0 -203000.0 -1.18 -1.7365 -0.9992 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E23 compound treatment 157280.0 -208000.0 -1.17 121080.0 -226000.0 -1.31 -1.7554 -0.9983 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 E24 compound treatment 131460.0 -234000.0 -1.32 89390.0 -258000.0 -1.5 -1.9881 -0.9979 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F01 mock treatment 423610.0 58500.0 0.33 420320.0 72900.0 0.42 0.5319 0.9924 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F02 mock treatment 221240.0 -144000.0 -0.81 337050.0 -10400.0 -0.06 -0.6151 -0.7576 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F03 compound treatment 250430.0 -115000.0 -0.65 377770.0 30300.0 0.18 -0.3319 -0.4963 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F04 compound treatment 377530.0 12500.0 0.07 343940.0 -3500.0 -0.02 0.0353 0.4827 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F05 compound treatment 398930.0 33900.0 0.19 355170.0 7730.0 0.04 0.1665 0.8502 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F06 compound treatment 171780.0 -193000.0 -1.09 209330.0 -138000.0 -0.8 -1.3358 -0.9886 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F07 compound treatment 416160.0 51100.0 0.29 412360.0 64900.0 0.38 0.4696 0.9912 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F08 compound treatment 346600.0 -18500.0 -0.1 245880.0 -102000.0 -0.59 -0.49 -0.8192 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F09 mock treatment 316010.0 -49100.0 -0.28 424360.0 76900.0 0.45 0.1202 0.2291 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F10 mock treatment 276330.0 -88700.0 -0.5 386350.0 38900.0 0.23 -0.1937 -0.3533 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F11 compound treatment 334560.0 -30500.0 -0.17 311600.0 -35800.0 -0.21 -0.2684 -0.9955 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F12 compound treatment 382560.0 17500.0 0.1 241190.0 -106000.0 -0.62 -0.3661 -0.5866 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F13 compound treatment 396810.0 31700.0 0.18 326580.0 -20900.0 -0.12 0.0408 0.1892 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F14 compound treatment 307710.0 -57400.0 -0.32 374900.0 27500.0 0.16 -0.1157 -0.3214 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F15 compound treatment 164590.0 -200000.0 -1.13 164800.0 -183000.0 -1.06 -1.547 -0.9995 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F16 compound treatment 215570.0 -149000.0 -0.84 185670.0 -162000.0 -0.94 -1.2585 -0.9985 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F17 mock treatment 289570.0 -75500.0 -0.42 260530.0 -86900.0 -0.5 -0.6569 -0.9964 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F18 mock treatment 394810.0 29700.0 0.17 418610.0 71200.0 0.41 0.4103 0.9211 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F19 compound treatment 110720.0 -254000.0 -1.43 150570.0 -197000.0 -1.14 -1.8198 -0.9937 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F20 compound treatment 265240.0 -99800.0 -0.56 173350.0 -174000.0 -1.01 -1.1113 -0.9617 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F21 compound treatment 141600.0 -223000.0 -1.26 196640.0 -151000.0 -0.87 -1.5079 -0.9842 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F22 compound treatment 382210.0 17100.0 0.1 239790.0 -108000.0 -0.62 -0.3732 -0.5907 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F23 compound treatment 219060.0 -146000.0 -0.82 372860.0 25400.0 0.15 -0.4769 -0.5712 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 F24 compound treatment 376640.0 11600.0 0.07 195630.0 -152000.0 -0.88 -0.5765 -0.653 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G01 compound treatment 429940.0 64900.0 0.37 250900.0 -96500.0 -0.56 -0.1376 -0.2059 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G02 compound treatment 286410.0 -78700.0 -0.44 299310.0 -48100.0 -0.28 -0.5105 -0.9753 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G03 mock treatment 363680.0 -1380.0 -0.01 250480.0 -97000.0 -0.56 -0.4031 -0.7168 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G04 mock treatment 441210.0 76100.0 0.43 379440.0 32000.0 0.19 0.4343 0.9298 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G05 compound treatment 158990.0 -206000.0 -1.16 155440.0 -192000.0 -1.11 -1.6077 -0.9998 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G06 compound treatment 168890.0 -196000.0 -1.1 168290.0 -179000.0 -1.04 -1.5156 -0.9995 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G07 compound treatment 114320.0 -251000.0 -1.41 164820.0 -183000.0 -1.06 -1.747 -0.99 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G08 compound treatment 133250.0 -232000.0 -1.3 162690.0 -185000.0 -1.07 -1.6804 -0.9952 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G09 compound treatment 274170.0 -90900.0 -0.51 366800.0 19400.0 0.11 -0.2824 -0.5391 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G10 compound treatment 385560.0 20500.0 0.12 305610.0 -41800.0 -0.24 -0.0899 -0.3348 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G11 compound treatment 171140.0 -194000.0 -1.09 155040.0 -192000.0 -1.12 -1.5609 -0.9999 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G12 compound treatment 306500.0 -58600.0 -0.33 303390.0 -44100.0 -0.26 -0.4138 -0.9921 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G13 compound treatment 191330.0 -174000.0 -0.98 275620.0 -71800.0 -0.42 -0.9861 -0.9276 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G14 compound treatment 249890.0 -115000.0 -0.65 230290.0 -117000.0 -0.68 -0.9389 -0.9997 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G15 compound treatment 410310.0 45200.0 0.25 259330.0 -88100.0 -0.51 -0.1812 -0.3174 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G16 compound treatment 189350.0 -176000.0 -0.99 206080.0 -141000.0 -0.82 -1.2791 -0.9956 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G17 compound treatment 236540.0 -129000.0 -0.72 262000.0 -85400.0 -0.5 -0.862 -0.983 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G18 compound treatment 138100.0 -227000.0 -1.28 169460.0 -178000.0 -1.03 -1.6333 -0.9944 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G19 mock treatment 446170.0 81100.0 0.46 410250.0 62800.0 0.36 0.5804 0.9937 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G20 mock treatment 368210.0 3150.0 0.02 232110.0 -115000.0 -0.67 -0.4604 -0.6881 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G21 compound treatment 165850.0 -199000.0 -1.12 172190.0 -175000.0 -1.02 -1.5117 -0.9988 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G22 compound treatment 312610.0 -52500.0 -0.3 256900.0 -90500.0 -0.53 -0.5801 -0.9629 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G23 compound treatment 347780.0 -17300.0 -0.1 269140.0 -78300.0 -0.45 -0.3899 -0.8395 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 G24 compound treatment 374560.0 9500.0 0.05 283120.0 -64300.0 -0.37 -0.226 -0.5996 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H01 compound treatment 300110.0 -65000.0 -0.37 398440.0 51000.0 0.3 -0.0494 -0.1051 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H02 compound treatment 379840.0 14800.0 0.08 309120.0 -38300.0 -0.22 -0.0983 -0.4143 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H03 mock treatment 438400.0 73300.0 0.41 150450.0 -197000.0 -1.14 -0.5159 -0.4247 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H04 mock treatment 462720.0 97700.0 0.55 396690.0 49200.0 0.29 0.5907 0.9535 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H05 compound treatment 398240.0 33200.0 0.19 379790.0 32300.0 0.19 0.2647 1.0 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H06 compound treatment 293920.0 -71100.0 -0.4 212730.0 -135000.0 -0.78 -0.8356 -0.9518 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H07 compound treatment 256990.0 -108000.0 -0.61 294480.0 -53000.0 -0.31 -0.6474 -0.9499 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H08 compound treatment 225930.0 -139000.0 -0.78 185920.0 -162000.0 -0.94 -1.2162 -0.996 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H09 compound treatment 187940.0 -177000.0 -1.0 153240.0 -194000.0 -1.13 -1.5014 -0.9982 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H10 compound treatment 235080.0 -130000.0 -0.73 220690.0 -127000.0 -0.74 -1.0372 -1.0 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H11 compound treatment 511800.0 147000.0 0.83 257380.0 -90100.0 -0.52 0.2148 0.2198 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H12 compound treatment 358240.0 -6820.0 -0.04 241760.0 -106000.0 -0.61 -0.4605 -0.7499 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H13 compound treatment 237970.0 -127000.0 -0.72 281220.0 -66200.0 -0.38 -0.7775 -0.9575 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H14 compound treatment 254880.0 -110000.0 -0.62 286080.0 -61400.0 -0.36 -0.6902 -0.9652 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H15 compound treatment 312590.0 -52500.0 -0.3 411750.0 64300.0 0.37 0.0548 0.1153 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H16 compound treatment 346100.0 -19000.0 -0.11 268250.0 -79200.0 -0.46 -0.4002 -0.8488 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H17 compound treatment 337820.0 -27200.0 -0.15 404910.0 57500.0 0.33 0.1272 0.3468 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H18 compound treatment 364920.0 -141.0 0.0 404810.0 57400.0 0.33 0.2347 0.7054 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H19 mock treatment 324670.0 -40400.0 -0.23 437460.0 90000.0 0.52 0.2084 0.3659 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H20 mock treatment 363520.0 -1540.0 -0.01 246330.0 -101000.0 -0.59 -0.4208 -0.7175 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H21 compound treatment 135790.0 -229000.0 -1.29 87520.0 -260000.0 -1.51 -1.9785 -0.997 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H22 compound treatment 288540.0 -76500.0 -0.43 279650.0 -67800.0 -0.39 -0.5826 -0.999 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H23 compound treatment 393870.0 28800.0 0.16 265230.0 -82200.0 -0.48 -0.2225 -0.4417 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 H24 compound treatment 248200.0 -117000.0 -0.66 215320.0 -132000.0 -0.77 -1.007 -0.9971 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I01 compound treatment 168400.0 -197000.0 -1.11 152380.0 -195000.0 -1.13 -1.5828 -0.9999 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I02 compound treatment 312740.0 -52300.0 -0.29 324900.0 -22500.0 -0.13 -0.3007 -0.9332 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I03 compound treatment 162480.0 -203000.0 -1.14 187540.0 -160000.0 -0.93 -1.4621 -0.9947 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I04 compound treatment 211130.0 -154000.0 -0.87 123310.0 -224000.0 -1.3 -1.5319 -0.9806 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I05 mock treatment 181090.0 -184000.0 -1.04 294100.0 -53300.0 -0.31 -0.9511 -0.8799 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I06 mock treatment 478750.0 114000.0 0.64 320270.0 -27200.0 -0.16 0.3411 0.5175 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I07 compound treatment 426730.0 61700.0 0.35 323570.0 -23900.0 -0.14 0.1476 0.3949 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I08 compound treatment 336690.0 -28400.0 -0.16 369470.0 22000.0 0.13 -0.0226 -0.1105 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I09 compound treatment 270580.0 -94500.0 -0.53 202400.0 -145000.0 -0.84 -0.9709 -0.9756 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I10 compound treatment 148960.0 -216000.0 -1.22 151490.0 -196000.0 -1.14 -1.6638 -0.9994 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I11 compound treatment 247250.0 -118000.0 -0.66 206510.0 -141000.0 -0.82 -1.0469 -0.9946 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I12 compound treatment 379420.0 14400.0 0.08 293410.0 -54000.0 -0.31 -0.1644 -0.5081 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I13 compound treatment 333040.0 -32000.0 -0.18 350240.0 2800.0 0.02 -0.116 -0.6409 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I14 compound treatment 213480.0 -152000.0 -0.85 191580.0 -156000.0 -0.9 -1.2426 -0.9996 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I15 compound treatment 471370.0 106000.0 0.6 289510.0 -57900.0 -0.34 0.1856 0.2704 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I16 compound treatment 353600.0 -11500.0 -0.06 280290.0 -67200.0 -0.39 -0.321 -0.8132 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I17 compound treatment 458320.0 93300.0 0.53 321570.0 -25900.0 -0.15 0.2651 0.4856 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I18 compound treatment 369180.0 4120.0 0.02 235220.0 -112000.0 -0.65 -0.4438 -0.6815 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I19 compound treatment 148980.0 -216000.0 -1.22 177160.0 -170000.0 -0.99 -1.5584 -0.9947 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I20 compound treatment 172800.0 -192000.0 -1.08 164010.0 -183000.0 -1.06 -1.5175 -1.0 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I21 mock treatment 446520.0 81500.0 0.46 467070.0 120000.0 0.69 0.8148 0.9798 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I22 mock treatment 415920.0 50900.0 0.29 319620.0 -27800.0 -0.16 0.0884 0.2689 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I23 compound treatment 404530.0 39500.0 0.22 332520.0 -14900.0 -0.09 0.0959 0.4023 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 I24 compound treatment 281380.0 -83700.0 -0.47 281130.0 -66300.0 -0.38 -0.605 -0.9949 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J01 compound treatment 14660.0 -350000.0 -1.97 14720.0 -333000.0 -1.93 -2.7593 -0.9999 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J02 compound treatment 323650.0 -41400.0 -0.23 195620.0 -152000.0 -0.88 -0.7874 -0.8645 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J03 compound treatment 290250.0 -74800.0 -0.42 252500.0 -94900.0 -0.55 -0.6871 -0.9912 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J04 compound treatment 180890.0 -184000.0 -1.04 274440.0 -73000.0 -0.42 -1.0325 -0.9219 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J05 mock treatment 402600.0 37500.0 0.21 236870.0 -111000.0 -0.64 -0.304 -0.4503 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J06 mock treatment 359620.0 -5440.0 -0.03 285530.0 -61900.0 -0.36 -0.2755 -0.7647 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J07 compound treatment 285220.0 -79800.0 -0.45 304900.0 -42500.0 -0.25 -0.4923 -0.9601 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J08 compound treatment 181560.0 -184000.0 -1.03 261920.0 -85500.0 -0.5 -1.0812 -0.9435 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J09 compound treatment 481410.0 116000.0 0.65 384390.0 36900.0 0.21 0.6147 0.8919 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J10 compound treatment 328770.0 -36300.0 -0.2 186720.0 -161000.0 -0.93 -0.8036 -0.8421 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J11 compound treatment 299520.0 -65500.0 -0.37 361630.0 14200.0 0.08 -0.2027 -0.5362 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J12 compound treatment 363960.0 -1100.0 -0.01 328390.0 -19100.0 -0.11 -0.0825 -0.7456 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J13 compound treatment 419600.0 54500.0 0.31 366480.0 19000.0 0.11 0.2952 0.9047 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J14 compound treatment 367950.0 2890.0 0.02 298010.0 -49400.0 -0.29 -0.1912 -0.6659 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J15 compound treatment 391200.0 26100.0 0.15 373650.0 26200.0 0.15 0.2115 0.9999 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J16 compound treatment 220860.0 -144000.0 -0.81 222290.0 -125000.0 -0.73 -1.0872 -0.9984 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J17 compound treatment 245410.0 -120000.0 -0.67 280430.0 -67000.0 -0.39 -0.7511 -0.9659 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J18 compound treatment 330030.0 -35000.0 -0.2 375900.0 28500.0 0.17 -0.0227 -0.0885 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J19 compound treatment 264210.0 -101000.0 -0.57 392820.0 45400.0 0.26 -0.2154 -0.3442 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J20 compound treatment 201880.0 -163000.0 -0.92 223690.0 -124000.0 -0.72 -1.1571 -0.9925 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J21 mock treatment 303610.0 -61500.0 -0.35 325280.0 -22200.0 -0.13 -0.3355 -0.9091 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J22 mock treatment 316050.0 -49000.0 -0.28 297630.0 -49800.0 -0.29 -0.3994 -0.9997 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J23 compound treatment 291460.0 -73600.0 -0.41 257700.0 -89700.0 -0.52 -0.661 -0.9936 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 J24 compound treatment 278630.0 -86400.0 -0.49 216980.0 -130000.0 -0.76 -0.8791 -0.9772 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K01 compound treatment 316840.0 -48200.0 -0.27 307440.0 -40000.0 -0.23 -0.356 -0.9969 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K02 compound treatment 354850.0 -10200.0 -0.06 256800.0 -90600.0 -0.53 -0.4124 -0.7798 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K03 compound treatment 379010.0 13900.0 0.08 351700.0 4260.0 0.02 0.073 0.8867 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K04 compound treatment 205990.0 -159000.0 -0.9 302160.0 -45300.0 -0.26 -0.8189 -0.8775 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K05 compound treatment 308020.0 -57000.0 -0.32 229490.0 -118000.0 -0.68 -0.7108 -0.9406 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K06 compound treatment 377050.0 12000.0 0.07 313920.0 -33500.0 -0.19 -0.0897 -0.4361 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K07 mock treatment 328520.0 -36500.0 -0.21 291330.0 -56100.0 -0.33 -0.3756 -0.9755 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K08 mock treatment 511700.0 147000.0 0.83 374300.0 26900.0 0.16 0.6939 0.826 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K09 compound treatment 323040.0 -42000.0 -0.24 242930.0 -105000.0 -0.61 -0.5959 -0.9158 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K10 compound treatment 287630.0 -77400.0 -0.44 440590.0 93100.0 0.54 0.0738 0.1063 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K11 compound treatment 345120.0 -19900.0 -0.11 457400.0 110000.0 0.64 0.3715 0.5738 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K12 compound treatment 391460.0 26400.0 0.15 403560.0 56100.0 0.33 0.3352 0.9369 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K13 compound treatment 316900.0 -48200.0 -0.27 402660.0 55200.0 0.32 0.0347 0.0828 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K14 compound treatment 475960.0 111000.0 0.62 348590.0 1150.0 0.01 0.4462 0.7146 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K15 mock treatment 381490.0 16400.0 0.09 483090.0 136000.0 0.79 0.6217 0.7848 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K16 mock treatment 466310.0 101000.0 0.57 348560.0 1120.0 0.01 0.4076 0.7151 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K17 compound treatment 304370.0 -60700.0 -0.34 345460.0 -1980.0 -0.01 -0.2497 -0.7305 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K18 compound treatment 421290.0 56200.0 0.32 436670.0 89200.0 0.52 0.5897 0.9722 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K19 compound treatment 121760.0 -243000.0 -1.37 119780.0 -228000.0 -1.32 -1.9021 -0.9998 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K20 compound treatment 331600.0 -33500.0 -0.19 392360.0 44900.0 0.26 0.051 0.1587 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K21 compound treatment 382200.0 17100.0 0.1 283860.0 -63600.0 -0.37 -0.1925 -0.5051 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K22 compound treatment 502650.0 138000.0 0.77 225760.0 -122000.0 -0.71 0.0487 0.0465 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K23 mock treatment 433360.0 68300.0 0.38 245320.0 -102000.0 -0.59 -0.1469 -0.2081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 K24 mock treatment 259610.0 -105000.0 -0.59 265530.0 -81900.0 -0.48 -0.7557 -0.9939 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L01 compound treatment 438250.0 73200.0 0.41 350500.0 3060.0 0.02 0.3039 0.7369 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L02 compound treatment 255400.0 -110000.0 -0.62 314720.0 -32700.0 -0.19 -0.5707 -0.8837 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L03 compound treatment 283320.0 -81700.0 -0.46 329610.0 -17800.0 -0.1 -0.3985 -0.8449 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L04 compound treatment 291610.0 -73500.0 -0.41 176350.0 -171000.0 -0.99 -0.994 -0.9247 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L05 compound treatment 402880.0 37800.0 0.21 313810.0 -33600.0 -0.2 0.0126 0.0437 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L06 compound treatment 288960.0 -76100.0 -0.43 253190.0 -94300.0 -0.55 -0.6894 -0.9927 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L07 mock treatment 376880.0 11800.0 0.07 458790.0 111000.0 0.65 0.5037 0.7759 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L08 mock treatment 243310.0 -122000.0 -0.69 397440.0 50000.0 0.29 -0.2796 -0.3757 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L09 compound treatment 436500.0 71400.0 0.4 313660.0 -33800.0 -0.2 0.1458 0.326 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L10 compound treatment 279010.0 -86100.0 -0.48 270880.0 -76600.0 -0.44 -0.6565 -0.9991 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L11 compound treatment 453480.0 88400.0 0.5 382430.0 35000.0 0.2 0.4954 0.9217 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L12 compound treatment 450340.0 85300.0 0.48 367230.0 19800.0 0.11 0.4206 0.8521 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L13 compound treatment 426210.0 61100.0 0.34 325280.0 -22200.0 -0.13 0.1525 0.4151 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L14 compound treatment 295740.0 -69300.0 -0.39 264000.0 -83400.0 -0.48 -0.6181 -0.9943 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L15 mock treatment 483560.0 118000.0 0.67 355280.0 7840.0 0.05 0.5038 0.7535 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L16 mock treatment 442460.0 77400.0 0.44 357610.0 10200.0 0.06 0.3498 0.7956 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L17 compound treatment 157410.0 -208000.0 -1.17 123750.0 -224000.0 -1.3 -1.7439 -0.9986 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L18 compound treatment 330120.0 -34900.0 -0.2 393440.0 46000.0 0.27 0.0495 0.1495 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L19 compound treatment 250970.0 -114000.0 -0.64 225920.0 -122000.0 -0.7 -0.9525 -0.9989 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L20 compound treatment 339290.0 -25800.0 -0.15 390880.0 43400.0 0.25 0.0755 0.2599 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L21 compound treatment 329950.0 -35100.0 -0.2 312760.0 -34700.0 -0.2 -0.282 -1.0 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L22 compound treatment 382620.0 17600.0 0.1 337380.0 -10100.0 -0.06 0.0286 0.2495 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L23 mock treatment 328810.0 -36300.0 -0.2 311710.0 -35700.0 -0.21 -0.2908 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 L24 mock treatment 364070.0 -991.0 -0.01 380330.0 32900.0 0.19 0.1309 0.6861 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M01 compound treatment 317290.0 -47800.0 -0.27 395550.0 48100.0 0.28 0.0071 0.0184 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M02 compound treatment 336160.0 -28900.0 -0.16 333030.0 -14400.0 -0.08 -0.1741 -0.9521 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M03 compound treatment 268890.0 -96200.0 -0.54 372850.0 25400.0 0.15 -0.2786 -0.4966 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M04 compound treatment 116000.0 -249000.0 -1.4 140160.0 -207000.0 -1.2 -1.8415 -0.9971 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M05 compound treatment 158640.0 -206000.0 -1.16 163360.0 -184000.0 -1.07 -1.5766 -0.9991 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M06 compound treatment 386180.0 21100.0 0.12 351910.0 4470.0 0.03 0.1024 0.8415 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M07 compound treatment 164960.0 -200000.0 -1.13 164960.0 -182000.0 -1.06 -1.5449 -0.9995 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M08 compound treatment 161030.0 -204000.0 -1.15 168500.0 -179000.0 -1.04 -1.546 -0.9987 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M09 mock treatment 280640.0 -84400.0 -0.48 295850.0 -51600.0 -0.3 -0.5476 -0.9751 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M10 mock treatment 421280.0 56200.0 0.32 445340.0 97900.0 0.57 0.6252 0.9619 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M11 compound treatment 352540.0 -12500.0 -0.07 421120.0 73700.0 0.43 0.2523 0.5826 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M12 compound treatment 300870.0 -64200.0 -0.36 297500.0 -49900.0 -0.29 -0.4603 -0.994 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M13 mock treatment 450490.0 85400.0 0.48 308520.0 -38900.0 -0.23 0.1805 0.3397 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M14 mock treatment 458400.0 93300.0 0.53 389040.0 41600.0 0.24 0.5421 0.9377 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M15 compound treatment 416400.0 51300.0 0.29 296990.0 -50500.0 -0.29 -0.0025 -0.0062 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M16 compound treatment 333970.0 -31100.0 -0.18 429760.0 82300.0 0.48 0.2138 0.4205 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M17 compound treatment 331950.0 -33100.0 -0.19 413600.0 66200.0 0.38 0.1395 0.327 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M18 compound treatment 334640.0 -30400.0 -0.17 362580.0 15100.0 0.09 -0.059 -0.3067 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M19 compound treatment 162270.0 -203000.0 -1.14 168000.0 -179000.0 -1.04 -1.5431 -0.9989 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M20 compound treatment 257440.0 -108000.0 -0.61 290810.0 -56600.0 -0.33 -0.6606 -0.9586 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M21 compound treatment 236380.0 -129000.0 -0.72 214780.0 -133000.0 -0.77 -1.0563 -0.9995 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M22 compound treatment 169170.0 -196000.0 -1.1 125530.0 -222000.0 -1.29 -1.6898 -0.997 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M23 compound treatment 172010.0 -193000.0 -1.09 147210.0 -200000.0 -1.16 -1.5896 -0.9995 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 M24 compound treatment 129360.0 -236000.0 -1.33 149290.0 -198000.0 -1.15 -1.7508 -0.9974 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N01 compound treatment 411930.0 46900.0 0.26 387230.0 39800.0 0.23 0.3497 0.9978 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N02 compound treatment 346050.0 -19000.0 -0.11 295610.0 -51800.0 -0.3 -0.2882 -0.9033 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N03 compound treatment 440200.0 75100.0 0.42 307800.0 -39600.0 -0.23 0.1365 0.2836 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N04 compound treatment 271540.0 -93500.0 -0.53 322120.0 -25300.0 -0.15 -0.4761 -0.8711 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N05 compound treatment 411640.0 46600.0 0.26 382930.0 35500.0 0.21 0.3309 0.9928 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N06 compound treatment 321820.0 -43200.0 -0.24 281330.0 -66100.0 -0.38 -0.4432 -0.976 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N07 compound treatment 374560.0 9500.0 0.05 263900.0 -83500.0 -0.48 -0.3048 -0.6253 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N08 compound treatment 410830.0 45800.0 0.26 346910.0 -532.0 0.0 0.18 0.6986 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N09 mock treatment 425810.0 60700.0 0.34 429980.0 82500.0 0.48 0.5803 0.9864 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N10 mock treatment 371320.0 6260.0 0.04 361050.0 13600.0 0.08 0.0807 0.9339 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N11 compound treatment 418400.0 53300.0 0.3 310400.0 -37000.0 -0.21 0.0604 0.1637 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N12 compound treatment 468520.0 103000.0 0.58 383570.0 36100.0 0.21 0.56 0.9047 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N13 mock treatment 437080.0 72000.0 0.41 401280.0 53800.0 0.31 0.5075 0.9917 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N14 mock treatment 467900.0 103000.0 0.58 376480.0 29000.0 0.17 0.5284 0.8765 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N15 compound treatment 355520.0 -9540.0 -0.05 192640.0 -155000.0 -0.9 -0.6728 -0.7481 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N16 compound treatment 262730.0 -102000.0 -0.58 322460.0 -25000.0 -0.14 -0.5098 -0.8582 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N17 compound treatment 406850.0 41800.0 0.24 393290.0 45800.0 0.27 0.3544 0.9981 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N18 compound treatment 292640.0 -72400.0 -0.41 279090.0 -68400.0 -0.4 -0.5686 -0.9999 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N19 compound treatment 336860.0 -28200.0 -0.16 412590.0 65100.0 0.38 0.1549 0.378 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N20 compound treatment 186420.0 -179000.0 -1.01 225650.0 -122000.0 -0.71 -1.2106 -0.9851 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N21 compound treatment 174040.0 -191000.0 -1.08 235200.0 -112000.0 -0.65 -1.2207 -0.9711 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N22 compound treatment 366180.0 1120.0 0.01 273300.0 -74100.0 -0.43 -0.2996 -0.6967 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N23 compound treatment 421410.0 56300.0 0.32 283160.0 -64300.0 -0.37 -0.0393 -0.0803 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 N24 compound treatment 377290.0 12200.0 0.07 328700.0 -18700.0 -0.11 -0.0282 -0.219 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O01 compound treatment 277940.0 -87100.0 -0.49 403420.0 56000.0 0.32 -0.1172 -0.1993 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O02 compound treatment 254120.0 -111000.0 -0.62 389640.0 42200.0 0.24 -0.2686 -0.4004 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O03 compound treatment 114400.0 -251000.0 -1.41 153980.0 -193000.0 -1.12 -1.7912 -0.9935 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O04 compound treatment 391210.0 26100.0 0.15 347890.0 448.0 0.0 0.1059 0.7195 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O05 compound treatment 184160.0 -181000.0 -1.02 175840.0 -172000.0 -1.0 -1.4238 -0.9999 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O06 compound treatment 406140.0 41100.0 0.23 389450.0 42000.0 0.24 0.3358 0.9997 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O07 compound treatment 166420.0 -199000.0 -1.12 175380.0 -172000.0 -1.0 -1.4963 -0.9984 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O08 compound treatment 154950.0 -210000.0 -1.18 139290.0 -208000.0 -1.21 -1.69 -0.9999 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O09 compound treatment 345990.0 -19100.0 -0.11 383790.0 36300.0 0.21 0.0731 0.3092 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O10 compound treatment 424740.0 59700.0 0.34 379630.0 32200.0 0.19 0.3696 0.9615 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O11 mock treatment 413880.0 48800.0 0.27 397810.0 50400.0 0.29 0.4009 0.9995 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O12 mock treatment 465930.0 101000.0 0.57 349760.0 2320.0 0.01 0.411 0.7236 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O13 compound treatment 350970.0 -14100.0 -0.08 354050.0 6610.0 0.04 -0.029 -0.3291 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O14 compound treatment 305970.0 -59100.0 -0.33 382720.0 35300.0 0.2 -0.0906 -0.2319 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O15 compound treatment 315200.0 -49900.0 -0.28 315370.0 -32100.0 -0.19 -0.33 -0.98 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O16 compound treatment 355170.0 -9890.0 -0.06 429930.0 82500.0 0.48 0.2989 0.6206 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O17 compound treatment 129620.0 -235000.0 -1.33 119200.0 -228000.0 -1.32 -1.8732 -1.0 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O18 compound treatment 181440.0 -184000.0 -1.03 156730.0 -191000.0 -1.11 -1.513 -0.9994 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O19 compound treatment 176360.0 -189000.0 -1.06 149140.0 -198000.0 -1.15 -1.5644 -0.9992 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O20 compound treatment 436160.0 71100.0 0.4 394960.0 47500.0 0.28 0.4779 0.9834 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O21 compound treatment 317780.0 -47300.0 -0.27 250650.0 -96800.0 -0.56 -0.5851 -0.9419 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O22 compound treatment 322400.0 -42700.0 -0.24 366400.0 19000.0 0.11 -0.0921 -0.3486 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O23 compound treatment 283250.0 -81800.0 -0.46 329670.0 -17800.0 -0.1 -0.3985 -0.8445 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 O24 compound treatment 319970.0 -45100.0 -0.25 290680.0 -56800.0 -0.33 -0.4123 -0.9918 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P01 compound treatment 345990.0 -19100.0 -0.11 333670.0 -13800.0 -0.08 -0.1324 -0.9894 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P02 compound treatment 178790.0 -186000.0 -1.05 359120.0 11700.0 0.07 -0.6936 -0.6601 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P03 compound treatment 342010.0 -23100.0 -0.13 263520.0 -83900.0 -0.49 -0.4359 -0.8654 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P04 compound treatment 248540.0 -117000.0 -0.66 372960.0 25500.0 0.15 -0.3592 -0.5342 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P05 compound treatment 244730.0 -120000.0 -0.68 284240.0 -63200.0 -0.37 -0.7382 -0.9584 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P06 compound treatment 196830.0 -168000.0 -0.95 243240.0 -104000.0 -0.6 -1.097 -0.9765 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P07 compound treatment 192350.0 -173000.0 -0.97 251250.0 -96200.0 -0.56 -1.082 -0.9652 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P08 compound treatment 279900.0 -85200.0 -0.48 237150.0 -110000.0 -0.64 -0.7913 -0.9899 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P09 compound treatment 307210.0 -57900.0 -0.33 236980.0 -110000.0 -0.64 -0.6833 -0.9508 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P10 compound treatment 330560.0 -34500.0 -0.19 364290.0 16800.0 0.1 -0.0682 -0.3139 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P11 mock treatment 262470.0 -103000.0 -0.58 308490.0 -39000.0 -0.23 -0.5681 -0.9161 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P12 mock treatment 261090.0 -104000.0 -0.59 268920.0 -78500.0 -0.46 -0.7359 -0.9923 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P13 compound treatment 137950.0 -227000.0 -1.28 113780.0 -234000.0 -1.36 -1.8623 -0.9996 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P14 compound treatment 263960.0 -101000.0 -0.57 238040.0 -109000.0 -0.63 -0.8511 -0.9985 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P15 compound treatment 216640.0 -148000.0 -0.84 215060.0 -132000.0 -0.77 -1.1337 -0.9991 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P16 compound treatment 171040.0 -194000.0 -1.09 184710.0 -163000.0 -0.94 -1.4397 -0.9974 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P17 compound treatment 4160.0 -361000.0 -2.03 3610.0 -344000.0 -1.99 -2.8466 -1.0 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P18 compound treatment 200600.0 -164000.0 -0.93 162880.0 -185000.0 -1.07 -1.4115 -0.9974 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P19 compound treatment 6500.0 -359000.0 -2.02 5710.0 -342000.0 -1.98 -2.8287 -1.0 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P20 compound treatment 239690.0 -125000.0 -0.71 234320.0 -113000.0 -0.66 -0.963 -0.9993 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P21 compound treatment 289790.0 -75300.0 -0.42 196540.0 -151000.0 -0.88 -0.9184 -0.9446 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P22 compound treatment 171880.0 -193000.0 -1.09 187170.0 -160000.0 -0.93 -1.4262 -0.9969 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P23 compound treatment 198800.0 -166000.0 -0.94 179700.0 -168000.0 -0.97 -1.3497 -0.9998 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2096 P24 compound treatment 248700.0 -116000.0 -0.66 235090.0 -112000.0 -0.65 -0.9239 -1.0 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A01 compound treatment 364440.0 11800.0 0.07 152930.0 -144000.0 -0.84 -0.5452 -0.649 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A02 compound treatment 202820.0 -150000.0 -0.84 294990.0 -2340.0 -0.01 -0.606 -0.7184 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A03 compound treatment 218270.0 -134000.0 -0.76 193640.0 -104000.0 -0.6 -0.9602 -0.9935 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A04 compound treatment 350300.0 -2350.0 -0.01 184530.0 -113000.0 -0.65 -0.4719 -0.7213 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A05 compound treatment 341680.0 -11000.0 -0.06 271890.0 -25400.0 -0.15 -0.148 -0.9253 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A06 compound treatment 84580.0 -268000.0 -1.51 15900.0 -281000.0 -1.63 -2.2212 -0.9992 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A07 compound treatment 249130.0 -104000.0 -0.58 249490.0 -47800.0 -0.28 -0.6083 -0.9424 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A08 compound treatment 279140.0 -73500.0 -0.41 324500.0 27200.0 0.16 -0.1812 -0.4092 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A09 compound treatment 330820.0 -21800.0 -0.12 166400.0 -131000.0 -0.76 -0.6238 -0.811 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A10 compound treatment 156720.0 -196000.0 -1.1 191240.0 -106000.0 -0.62 -1.215 -0.962 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A11 compound treatment 176720.0 -176000.0 -0.99 268340.0 -29000.0 -0.17 -0.8192 -0.8155 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A12 compound treatment 224540.0 -128000.0 -0.72 141180.0 -156000.0 -0.91 -1.1503 -0.9936 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A13 mock treatment 266620.0 -86000.0 -0.48 201350.0 -96000.0 -0.56 -0.7361 -0.9976 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A14 mock treatment 294950.0 -57700.0 -0.32 308920.0 11600.0 0.07 -0.1822 -0.5492 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A15 compound treatment 196600.0 -156000.0 -0.88 128540.0 -169000.0 -0.98 -1.3134 -0.9985 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A16 compound treatment 267270.0 -85400.0 -0.48 211410.0 -85900.0 -0.5 -0.6922 -0.9998 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A17 compound treatment 251100.0 -102000.0 -0.57 262240.0 -35100.0 -0.2 -0.5482 -0.9033 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A18 compound treatment 235270.0 -117000.0 -0.66 327050.0 29700.0 0.17 -0.3454 -0.5058 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A19 compound treatment 256210.0 -96400.0 -0.54 271940.0 -25400.0 -0.15 -0.488 -0.8676 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A20 compound treatment 193920.0 -159000.0 -0.89 178780.0 -119000.0 -0.69 -1.118 -0.9916 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A21 compound treatment 231240.0 -121000.0 -0.68 238080.0 -59300.0 -0.34 -0.7263 -0.9494 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A22 compound treatment 294040.0 -58600.0 -0.33 336920.0 39600.0 0.23 -0.071 -0.1766 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A23 compound treatment 141560.0 -211000.0 -1.19 167680.0 -130000.0 -0.75 -1.372 -0.9756 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 A24 compound treatment 248040.0 -105000.0 -0.59 163070.0 -134000.0 -0.78 -0.967 -0.9905 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B01 compound treatment 321050.0 -31600.0 -0.18 326600.0 29300.0 0.17 -0.0058 -0.0235 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B02 compound treatment 418360.0 65700.0 0.37 285700.0 -11600.0 -0.07 0.2139 0.5688 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B03 compound treatment 222630.0 -130000.0 -0.73 270810.0 -26500.0 -0.15 -0.6263 -0.8374 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B04 compound treatment 254300.0 -98400.0 -0.55 372320.0 75000.0 0.43 -0.084 -0.1193 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B05 compound treatment 355000.0 2350.0 0.01 314850.0 17500.0 0.1 0.0812 0.7925 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B06 compound treatment 175870.0 -177000.0 -1.0 188060.0 -109000.0 -0.63 -1.1518 -0.9763 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B07 compound treatment 169280.0 -183000.0 -1.03 132130.0 -165000.0 -0.96 -1.4074 -0.9993 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B08 compound treatment 267470.0 -85200.0 -0.48 212800.0 -84500.0 -0.49 -0.6857 -0.9999 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B09 compound treatment 174880.0 -178000.0 -1.0 227530.0 -69800.0 -0.4 -0.9939 -0.9207 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B10 compound treatment 216930.0 -136000.0 -0.76 202500.0 -94800.0 -0.55 -0.9292 -0.987 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B11 compound treatment 278960.0 -73700.0 -0.41 244430.0 -52900.0 -0.31 -0.5103 -0.989 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B12 compound treatment 314080.0 -38600.0 -0.22 211240.0 -86100.0 -0.5 -0.5066 -0.9304 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B13 mock treatment 387360.0 34700.0 0.2 310130.0 12800.0 0.07 0.1906 0.9121 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B14 mock treatment 420740.0 68100.0 0.38 356000.0 58700.0 0.34 0.5116 0.9982 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B15 compound treatment 361370.0 8720.0 0.05 199700.0 -97600.0 -0.57 -0.3657 -0.6434 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B16 compound treatment 208680.0 -144000.0 -0.81 195810.0 -102000.0 -0.59 -0.9894 -0.9877 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B17 compound treatment 279380.0 -73300.0 -0.41 250340.0 -47000.0 -0.27 -0.4844 -0.9798 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B18 compound treatment 241200.0 -111000.0 -0.63 131050.0 -166000.0 -0.96 -1.1255 -0.9783 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B19 compound treatment 259910.0 -92700.0 -0.52 163610.0 -134000.0 -0.78 -0.9175 -0.9815 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B20 compound treatment 308290.0 -44400.0 -0.25 310330.0 13000.0 0.08 -0.1233 -0.4726 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B21 compound treatment 360970.0 8320.0 0.05 296450.0 -884.0 -0.01 0.0295 0.626 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B22 compound treatment 280200.0 -72500.0 -0.41 223790.0 -73500.0 -0.43 -0.59 -0.9998 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B23 compound treatment 283700.0 -69000.0 -0.39 309230.0 11900.0 0.07 -0.2257 -0.5725 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 B24 compound treatment 308590.0 -44100.0 -0.25 248750.0 -48600.0 -0.28 -0.3746 -0.998 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C01 compound treatment 306730.0 -45900.0 -0.26 221130.0 -76200.0 -0.44 -0.4953 -0.9674 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C02 compound treatment 347890.0 -4760.0 -0.03 227650.0 -69700.0 -0.4 -0.3047 -0.7523 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C03 compound treatment 323240.0 -29400.0 -0.17 191700.0 -106000.0 -0.61 -0.5503 -0.8671 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C04 compound treatment 279360.0 -73300.0 -0.41 194300.0 -103000.0 -0.6 -0.7143 -0.9836 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C05 compound treatment 325440.0 -27200.0 -0.15 280800.0 -16500.0 -0.1 -0.1761 -0.9745 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C06 compound treatment 275910.0 -76700.0 -0.43 314110.0 16800.0 0.1 -0.2367 -0.5345 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C07 compound treatment 343850.0 -8800.0 -0.05 210890.0 -86400.0 -0.5 -0.3895 -0.7732 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C08 compound treatment 303200.0 -49500.0 -0.28 202200.0 -95100.0 -0.55 -0.587 -0.9498 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C09 compound treatment 192490.0 -160000.0 -0.9 171310.0 -126000.0 -0.73 -1.1543 -0.9946 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C10 compound treatment 320900.0 -31800.0 -0.18 240370.0 -57000.0 -0.33 -0.36 -0.9584 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C11 mock treatment 323090.0 -29600.0 -0.17 227530.0 -69800.0 -0.4 -0.4039 -0.9228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C12 mock treatment 388020.0 35400.0 0.2 271970.0 -25400.0 -0.15 0.0368 0.1486 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C13 compound treatment 275040.0 -77600.0 -0.44 322800.0 25500.0 0.15 -0.2045 -0.4434 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C14 compound treatment 163090.0 -190000.0 -1.07 85770.0 -212000.0 -1.23 -1.6222 -0.9976 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C15 mock treatment 238100.0 -115000.0 -0.64 293710.0 -3620.0 -0.02 -0.4708 -0.7298 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C16 mock treatment 236570.0 -116000.0 -0.65 256890.0 -40400.0 -0.23 -0.6279 -0.9044 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C17 compound treatment 274900.0 -77800.0 -0.44 176610.0 -121000.0 -0.7 -0.8046 -0.9744 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C18 compound treatment 357650.0 5000.0 0.03 207690.0 -89600.0 -0.52 -0.3477 -0.6678 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C19 compound treatment 253370.0 -99300.0 -0.56 130800.0 -167000.0 -0.97 -1.0781 -0.9662 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C20 compound treatment 31280.0 -321000.0 -1.81 7090.0 -290000.0 -1.68 -2.4695 -0.9994 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C21 compound treatment 208000.0 -145000.0 -0.81 118960.0 -178000.0 -1.03 -1.3073 -0.993 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C22 compound treatment 300500.0 -52200.0 -0.29 176610.0 -121000.0 -0.7 -0.7027 -0.9255 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C23 compound treatment 243910.0 -109000.0 -0.61 169050.0 -128000.0 -0.74 -0.9589 -0.9953 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 C24 compound treatment 223040.0 -130000.0 -0.73 262410.0 -34900.0 -0.2 -0.6592 -0.8705 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D01 compound treatment 434450.0 81800.0 0.46 393570.0 96200.0 0.56 0.7203 0.9954 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D02 compound treatment 319840.0 -32800.0 -0.18 243360.0 -54000.0 -0.31 -0.3519 -0.9683 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D03 compound treatment 335270.0 -17400.0 -0.1 198740.0 -98600.0 -0.57 -0.4735 -0.8162 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D04 compound treatment 384270.0 31600.0 0.18 200880.0 -96500.0 -0.56 -0.2697 -0.4594 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D05 compound treatment 326850.0 -25800.0 -0.15 323840.0 26500.0 0.15 0.006 0.0283 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D06 compound treatment 289340.0 -63300.0 -0.36 241920.0 -55400.0 -0.32 -0.4793 -0.9987 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D07 compound treatment 312320.0 -40300.0 -0.23 266880.0 -30500.0 -0.18 -0.2854 -0.9923 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D08 compound treatment 204370.0 -148000.0 -0.83 114680.0 -183000.0 -1.06 -1.3393 -0.993 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D09 compound treatment 323520.0 -29100.0 -0.16 215840.0 -81500.0 -0.47 -0.4501 -0.8998 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D10 compound treatment 205440.0 -147000.0 -0.83 160680.0 -137000.0 -0.79 -1.1464 -0.9998 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D11 mock treatment 368510.0 15900.0 0.09 289180.0 -8150.0 -0.05 0.0297 0.2939 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D12 mock treatment 441450.0 88800.0 0.5 323480.0 26100.0 0.15 0.4607 0.8819 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D13 compound treatment 400020.0 47400.0 0.27 185920.0 -111000.0 -0.65 -0.2683 -0.3839 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D14 compound treatment 415080.0 62400.0 0.35 179360.0 -118000.0 -0.68 -0.2353 -0.3059 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D15 mock treatment 421540.0 68900.0 0.39 245960.0 -51400.0 -0.3 0.0636 0.13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D16 mock treatment 373870.0 21200.0 0.12 274880.0 -22500.0 -0.13 -0.0076 -0.0431 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D17 compound treatment 373410.0 20800.0 0.12 234800.0 -62500.0 -0.36 -0.1738 -0.4561 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D18 compound treatment 243260.0 -109000.0 -0.62 242920.0 -54400.0 -0.32 -0.6586 -0.9518 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D19 compound treatment 409320.0 56700.0 0.32 190110.0 -107000.0 -0.62 -0.2141 -0.3064 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D20 compound treatment 256080.0 -96600.0 -0.54 203320.0 -94000.0 -0.55 -0.7699 -1.0 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D21 compound treatment 269090.0 -83600.0 -0.47 159940.0 -137000.0 -0.8 -0.8961 -0.9684 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D22 compound treatment 241540.0 -111000.0 -0.63 155040.0 -142000.0 -0.83 -1.0258 -0.9907 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D23 compound treatment 228820.0 -124000.0 -0.7 190000.0 -107000.0 -0.62 -0.9331 -0.9984 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 D24 compound treatment 339810.0 -12800.0 -0.07 299090.0 1760.0 0.01 -0.0439 -0.6015 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E01 mock treatment 404930.0 52300.0 0.29 339010.0 41700.0 0.24 0.379 0.9952 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E02 mock treatment 325920.0 -26700.0 -0.15 364160.0 66800.0 0.39 0.1676 0.4032 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E03 compound treatment 223240.0 -129000.0 -0.73 255630.0 -41700.0 -0.24 -0.6862 -0.8939 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E04 compound treatment 367550.0 14900.0 0.08 218400.0 -78900.0 -0.46 -0.2644 -0.5681 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E05 compound treatment 326150.0 -26500.0 -0.15 199760.0 -97600.0 -0.57 -0.5056 -0.864 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E06 compound treatment 188960.0 -164000.0 -0.92 104640.0 -193000.0 -1.12 -1.4418 -0.9954 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E07 compound treatment 337380.0 -15300.0 -0.09 242240.0 -55100.0 -0.32 -0.2867 -0.8665 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E08 compound treatment 293120.0 -59500.0 -0.34 239650.0 -57700.0 -0.33 -0.4735 -1.0 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E09 mock treatment 306810.0 -45800.0 -0.26 208890.0 -88400.0 -0.51 -0.5452 -0.9495 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E10 mock treatment 298240.0 -54400.0 -0.31 250990.0 -46300.0 -0.27 -0.4066 -0.9979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E11 compound treatment 393810.0 41200.0 0.23 316440.0 19100.0 0.11 0.2422 0.943 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E12 compound treatment 48250.0 -304000.0 -1.71 41670.0 -256000.0 -1.48 -2.2601 -0.9974 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E13 compound treatment 201990.0 -151000.0 -0.85 227680.0 -69700.0 -0.4 -0.8854 -0.9425 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E14 compound treatment 79710.0 -273000.0 -1.54 38560.0 -259000.0 -1.5 -2.1477 -0.9999 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E15 compound treatment 287850.0 -64800.0 -0.36 179850.0 -117000.0 -0.68 -0.7397 -0.9571 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E16 compound treatment 262690.0 -90000.0 -0.51 278400.0 -18900.0 -0.11 -0.4357 -0.8409 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E17 mock treatment 303430.0 -49200.0 -0.28 288000.0 -9330.0 -0.05 -0.2342 -0.8296 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E18 mock treatment 321780.0 -30900.0 -0.17 250790.0 -46500.0 -0.27 -0.3138 -0.9773 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E19 compound treatment 245150.0 -108000.0 -0.61 157330.0 -140000.0 -0.81 -1.0021 -0.9895 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E20 compound treatment 278370.0 -74300.0 -0.42 137150.0 -160000.0 -0.93 -0.9526 -0.935 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E21 compound treatment 232430.0 -120000.0 -0.68 168960.0 -128000.0 -0.74 -1.005 -0.9989 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E22 compound treatment 394730.0 42100.0 0.24 146210.0 -151000.0 -0.88 -0.4522 -0.4981 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E23 compound treatment 367680.0 15000.0 0.08 234300.0 -63000.0 -0.37 -0.1987 -0.5294 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 E24 compound treatment 316180.0 -36500.0 -0.21 187940.0 -109000.0 -0.63 -0.5938 -0.8905 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F01 mock treatment 402980.0 50300.0 0.28 349570.0 52200.0 0.3 0.4146 0.9994 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F02 mock treatment 292230.0 -60400.0 -0.34 379040.0 81700.0 0.47 0.0945 0.1621 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F03 compound treatment 246130.0 -107000.0 -0.6 204550.0 -92800.0 -0.54 -0.8045 -0.9985 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F04 compound treatment 296050.0 -56600.0 -0.32 323770.0 26400.0 0.15 -0.1169 -0.3306 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F05 compound treatment 181280.0 -171000.0 -0.96 184610.0 -113000.0 -0.65 -1.1444 -0.982 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F06 compound treatment 220480.0 -132000.0 -0.74 197210.0 -100000.0 -0.58 -0.9367 -0.9925 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F07 compound treatment 262780.0 -89900.0 -0.51 207270.0 -90100.0 -0.52 -0.7271 -0.9999 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F08 compound treatment 273340.0 -79300.0 -0.45 302320.0 4990.0 0.03 -0.2953 -0.6599 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F09 mock treatment 421030.0 68400.0 0.38 357480.0 60100.0 0.35 0.5188 0.9988 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F10 mock treatment 359890.0 7240.0 0.04 271900.0 -25400.0 -0.15 -0.0755 -0.4932 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F11 compound treatment 246940.0 -106000.0 -0.6 143680.0 -154000.0 -0.89 -1.0509 -0.9807 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F12 compound treatment 67360.0 -285000.0 -1.61 69870.0 -227000.0 -1.32 -2.0684 -0.9952 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F13 compound treatment 168920.0 -184000.0 -1.03 188380.0 -109000.0 -0.63 -1.1782 -0.972 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F14 compound treatment 371080.0 18400.0 0.1 175700.0 -122000.0 -0.71 -0.4254 -0.5967 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F15 compound treatment 296650.0 -56000.0 -0.32 132180.0 -165000.0 -0.96 -0.9002 -0.8927 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F16 compound treatment 290260.0 -62400.0 -0.35 194830.0 -103000.0 -0.59 -0.6687 -0.9685 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F17 mock treatment 325840.0 -26800.0 -0.15 207700.0 -89600.0 -0.52 -0.4743 -0.8762 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F18 mock treatment 422600.0 69900.0 0.39 226560.0 -70800.0 -0.41 -0.0118 -0.0207 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F19 compound treatment 312640.0 -40000.0 -0.23 156910.0 -140000.0 -0.81 -0.7351 -0.87 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F20 compound treatment 207570.0 -145000.0 -0.82 237780.0 -59600.0 -0.35 -0.8217 -0.9267 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F21 compound treatment 296000.0 -56700.0 -0.32 209600.0 -87700.0 -0.51 -0.5853 -0.9747 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F22 compound treatment 323390.0 -29300.0 -0.16 205310.0 -92000.0 -0.53 -0.4938 -0.8842 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F23 compound treatment 189520.0 -163000.0 -0.92 177500.0 -120000.0 -0.69 -1.1408 -0.9905 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 F24 compound treatment 174520.0 -178000.0 -1.0 196580.0 -101000.0 -0.58 -1.1222 -0.967 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G01 compound treatment 308210.0 -44400.0 -0.25 385730.0 88400.0 0.51 0.1856 0.3254 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G02 compound treatment 243140.0 -110000.0 -0.62 370260.0 72900.0 0.42 -0.1369 -0.1831 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G03 mock treatment 345160.0 -7490.0 -0.04 221030.0 -76300.0 -0.44 -0.3427 -0.771 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G04 mock treatment 222240.0 -130000.0 -0.73 345950.0 48600.0 0.28 -0.3198 -0.4066 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G05 compound treatment 267130.0 -85500.0 -0.48 348370.0 51000.0 0.3 -0.1311 -0.232 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G06 compound treatment 308160.0 -44500.0 -0.25 313400.0 16100.0 0.09 -0.1112 -0.4162 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G07 compound treatment 177800.0 -175000.0 -0.98 86360.0 -211000.0 -1.22 -1.5612 -0.9942 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G08 compound treatment 325600.0 -27100.0 -0.15 268370.0 -29000.0 -0.17 -0.2265 -0.9988 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G09 compound treatment 310340.0 -42300.0 -0.24 163640.0 -134000.0 -0.78 -0.7167 -0.8836 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G10 compound treatment 400840.0 48200.0 0.27 347580.0 50200.0 0.29 0.3979 0.9994 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G11 compound treatment 220960.0 -132000.0 -0.74 165790.0 -132000.0 -0.76 -1.0637 -0.9999 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G12 compound treatment 179470.0 -173000.0 -0.97 192070.0 -105000.0 -0.61 -1.121 -0.9746 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G13 compound treatment 432800.0 80100.0 0.45 229230.0 -68100.0 -0.39 0.0398 0.0663 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G14 compound treatment 248180.0 -104000.0 -0.59 131240.0 -166000.0 -0.96 -1.097 -0.972 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G15 compound treatment 360290.0 7640.0 0.04 277080.0 -20300.0 -0.12 -0.0526 -0.4209 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G16 compound treatment 191170.0 -161000.0 -0.91 284970.0 -12400.0 -0.07 -0.6935 -0.7605 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G17 compound treatment 280560.0 -72100.0 -0.41 200650.0 -96700.0 -0.56 -0.6834 -0.9874 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G18 compound treatment 268130.0 -84500.0 -0.48 204890.0 -92400.0 -0.54 -0.7155 -0.9982 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G19 mock treatment 398180.0 45500.0 0.26 280960.0 -16400.0 -0.09 0.1141 0.4174 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G20 mock treatment 374840.0 22200.0 0.12 223760.0 -73600.0 -0.43 -0.2134 -0.4799 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G21 compound treatment 290820.0 -61800.0 -0.35 220820.0 -76500.0 -0.44 -0.5599 -0.9928 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G22 compound treatment 263610.0 -89000.0 -0.5 257120.0 -40200.0 -0.23 -0.5193 -0.9394 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G23 compound treatment 249540.0 -103000.0 -0.58 261320.0 -36000.0 -0.21 -0.5581 -0.9047 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 G24 compound treatment 163380.0 -189000.0 -1.07 135160.0 -162000.0 -0.94 -1.4185 -0.9981 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H01 compound treatment 351740.0 -910.0 -0.01 246290.0 -51000.0 -0.3 -0.2129 -0.7192 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H02 compound treatment 418010.0 65400.0 0.37 167310.0 -130000.0 -0.75 -0.273 -0.3254 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H03 mock treatment 157540.0 -195000.0 -1.1 263700.0 -33600.0 -0.2 -0.9146 -0.8199 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H04 mock treatment 310580.0 -42100.0 -0.24 310720.0 13400.0 0.08 -0.1126 -0.4517 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H05 compound treatment 195360.0 -157000.0 -0.89 183900.0 -113000.0 -0.66 -1.0913 -0.9893 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H06 compound treatment 417440.0 64800.0 0.36 242490.0 -54800.0 -0.32 0.033 0.0682 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H07 compound treatment 304970.0 -47700.0 -0.27 254920.0 -42400.0 -0.25 -0.3637 -0.999 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H08 compound treatment 341610.0 -11000.0 -0.06 309490.0 12200.0 0.07 0.0059 0.0628 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H09 compound treatment 127120.0 -226000.0 -1.27 125980.0 -171000.0 -0.99 -1.6005 -0.9927 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H10 compound treatment 345000.0 -7650.0 -0.04 315330.0 18000.0 0.1 0.0433 0.3839 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H11 compound treatment 208640.0 -144000.0 -0.81 159450.0 -138000.0 -0.8 -1.1387 -1.0 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H12 compound treatment 292560.0 -60100.0 -0.34 194080.0 -103000.0 -0.6 -0.6626 -0.9635 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H13 compound treatment 161720.0 -191000.0 -1.07 146690.0 -151000.0 -0.87 -1.3778 -0.9947 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H14 compound treatment 258970.0 -93700.0 -0.53 229280.0 -68100.0 -0.39 -0.652 -0.9898 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H15 compound treatment 245360.0 -107000.0 -0.6 238850.0 -58500.0 -0.34 -0.6669 -0.9628 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H16 compound treatment 147050.0 -206000.0 -1.16 238260.0 -59100.0 -0.34 -1.0607 -0.8787 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H17 compound treatment 313790.0 -38900.0 -0.22 300870.0 3540.0 0.02 -0.1402 -0.638 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H18 compound treatment 239220.0 -113000.0 -0.64 247790.0 -49500.0 -0.29 -0.6547 -0.935 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H19 mock treatment 438890.0 86200.0 0.49 370080.0 72700.0 0.42 0.6416 0.9976 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H20 mock treatment 427410.0 74800.0 0.42 267690.0 -29600.0 -0.17 0.176 0.3872 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H21 compound treatment 292320.0 -60300.0 -0.34 270580.0 -26800.0 -0.16 -0.3499 -0.937 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H22 compound treatment 381660.0 29000.0 0.16 214490.0 -82800.0 -0.48 -0.2242 -0.4419 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H23 compound treatment 312720.0 -39900.0 -0.22 228640.0 -68700.0 -0.4 -0.4406 -0.9633 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 H24 compound treatment 190520.0 -162000.0 -0.91 204550.0 -92800.0 -0.54 -1.0259 -0.9682 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I01 compound treatment 376900.0 24200.0 0.14 346090.0 48800.0 0.28 0.2965 0.9442 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I02 compound treatment 245500.0 -107000.0 -0.6 252960.0 -44400.0 -0.26 -0.6085 -0.9279 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I03 compound treatment 438420.0 85800.0 0.48 204160.0 -93200.0 -0.54 -0.0407 -0.0561 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I04 compound treatment 334160.0 -18500.0 -0.1 209730.0 -87600.0 -0.51 -0.4328 -0.8346 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I05 mock treatment 372270.0 19600.0 0.11 322580.0 25200.0 0.15 0.1816 0.9903 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I06 mock treatment 415450.0 62800.0 0.35 337280.0 39900.0 0.23 0.4138 0.979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I07 compound treatment 209540.0 -143000.0 -0.81 209070.0 -88300.0 -0.51 -0.9316 -0.976 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I08 compound treatment 227760.0 -125000.0 -0.7 215330.0 -82000.0 -0.48 -0.8334 -0.9819 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I09 compound treatment 400520.0 47900.0 0.27 318950.0 21600.0 0.13 0.2792 0.9394 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I10 compound treatment 409340.0 56700.0 0.32 320580.0 23200.0 0.13 0.321 0.9265 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I11 compound treatment 343840.0 -8810.0 -0.05 195850.0 -101000.0 -0.59 -0.4512 -0.764 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I12 compound treatment 197310.0 -155000.0 -0.87 159060.0 -138000.0 -0.8 -1.1854 -0.9991 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I13 compound treatment 260980.0 -91700.0 -0.52 256640.0 -40700.0 -0.24 -0.5318 -0.9371 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I14 compound treatment 382980.0 30300.0 0.17 255520.0 -41800.0 -0.24 -0.0507 -0.1711 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I15 compound treatment 306500.0 -46200.0 -0.26 210890.0 -86400.0 -0.5 -0.5382 -0.9532 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I16 compound treatment 250500.0 -102000.0 -0.58 311230.0 13900.0 0.08 -0.3496 -0.6021 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I17 compound treatment 223200.0 -129000.0 -0.73 249060.0 -48300.0 -0.28 -0.7133 -0.9137 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I18 compound treatment 312660.0 -40000.0 -0.23 319100.0 21800.0 0.13 -0.0699 -0.2709 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I19 compound treatment 274830.0 -77800.0 -0.44 347400.0 50100.0 0.29 -0.1045 -0.1988 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I20 compound treatment 254090.0 -98600.0 -0.55 185310.0 -112000.0 -0.65 -0.8517 -0.9969 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I21 mock treatment 254350.0 -98300.0 -0.55 246420.0 -50900.0 -0.3 -0.6001 -0.9567 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I22 mock treatment 164930.0 -188000.0 -1.06 306750.0 9420.0 0.05 -0.7086 -0.6697 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I23 compound treatment 197210.0 -155000.0 -0.88 237370.0 -60000.0 -0.35 -0.8647 -0.9183 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 I24 compound treatment 256430.0 -96200.0 -0.54 236330.0 -61000.0 -0.35 -0.6332 -0.9787 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J01 compound treatment 222820.0 -130000.0 -0.73 361830.0 64500.0 0.37 -0.2523 -0.3073 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J02 compound treatment 328160.0 -24500.0 -0.14 200070.0 -97300.0 -0.56 -0.4963 -0.8548 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J03 compound treatment 239110.0 -114000.0 -0.64 316080.0 18700.0 0.11 -0.3751 -0.5785 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J04 compound treatment 336190.0 -16500.0 -0.09 343800.0 46500.0 0.27 0.125 0.4387 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J05 mock treatment 353790.0 1140.0 0.01 316380.0 19000.0 0.11 0.0826 0.7469 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J06 mock treatment 285120.0 -67500.0 -0.38 231710.0 -65600.0 -0.38 -0.5379 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J07 compound treatment 342590.0 -10100.0 -0.06 312250.0 14900.0 0.09 0.0211 0.2043 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J08 compound treatment 348090.0 -4560.0 -0.03 229620.0 -67700.0 -0.39 -0.2958 -0.7517 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J09 compound treatment 171210.0 -181000.0 -1.02 162080.0 -135000.0 -0.78 -1.2769 -0.9915 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J10 compound treatment 285080.0 -67600.0 -0.38 225440.0 -71900.0 -0.42 -0.5638 -0.999 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J11 compound treatment 247130.0 -106000.0 -0.59 226750.0 -70600.0 -0.41 -0.7095 -0.9835 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J12 compound treatment 171570.0 -181000.0 -1.02 159360.0 -138000.0 -0.8 -1.2866 -0.9928 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J13 compound treatment 322760.0 -29900.0 -0.17 250420.0 -46900.0 -0.27 -0.3114 -0.9733 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J14 compound treatment 326680.0 -26000.0 -0.15 177340.0 -120000.0 -0.7 -0.5954 -0.8374 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J15 compound treatment 284190.0 -68500.0 -0.39 177230.0 -120000.0 -0.7 -0.765 -0.9611 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J16 compound treatment 384060.0 31400.0 0.18 259270.0 -38100.0 -0.22 -0.0311 -0.1098 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J17 compound treatment 172490.0 -180000.0 -1.01 144050.0 -153000.0 -0.89 -1.3457 -0.9978 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J18 compound treatment 389180.0 36500.0 0.21 326020.0 28700.0 0.17 0.2631 0.9945 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J19 compound treatment 307890.0 -44800.0 -0.25 249090.0 -48200.0 -0.28 -0.376 -0.9986 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J20 compound treatment 272740.0 -79900.0 -0.45 183680.0 -114000.0 -0.66 -0.7842 -0.9827 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J21 mock treatment 250050.0 -103000.0 -0.58 306680.0 9350.0 0.05 -0.3701 -0.6379 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J22 mock treatment 208120.0 -145000.0 -0.81 260960.0 -36400.0 -0.21 -0.7245 -0.8619 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J23 compound treatment 342100.0 -10600.0 -0.06 207540.0 -89800.0 -0.52 -0.4102 -0.7827 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 J24 compound treatment 215170.0 -137000.0 -0.77 256750.0 -40600.0 -0.24 -0.7137 -0.8822 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K01 compound treatment 349660.0 -2990.0 -0.02 383290.0 86000.0 0.5 0.3406 0.6828 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K02 compound treatment 430050.0 77400.0 0.44 182370.0 -115000.0 -0.67 -0.1633 -0.2051 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K03 compound treatment 414090.0 61400.0 0.35 328800.0 31500.0 0.18 0.3736 0.9554 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K04 compound treatment 360200.0 7550.0 0.04 274270.0 -23100.0 -0.13 -0.0645 -0.4598 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K05 compound treatment 329300.0 -23400.0 -0.13 218940.0 -78400.0 -0.45 -0.4144 -0.8757 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K06 compound treatment 284170.0 -68500.0 -0.39 298740.0 1410.0 0.01 -0.2668 -0.692 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K07 mock treatment 396450.0 43800.0 0.25 331430.0 34100.0 0.2 0.3142 0.994 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K08 mock treatment 408910.0 56300.0 0.32 336500.0 39200.0 0.23 0.3846 0.9867 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K09 compound treatment 158840.0 -194000.0 -1.09 165290.0 -132000.0 -0.77 -1.313 -0.985 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K10 compound treatment 252770.0 -99900.0 -0.56 136800.0 -161000.0 -0.93 -1.0559 -0.9708 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K11 compound treatment 288450.0 -64200.0 -0.36 276080.0 -21300.0 -0.12 -0.3427 -0.8975 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K12 compound treatment 397880.0 45200.0 0.25 300980.0 3650.0 0.02 0.195 0.7632 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K13 compound treatment 286100.0 -66600.0 -0.37 206630.0 -90700.0 -0.53 -0.6369 -0.9862 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K14 compound treatment 258080.0 -94600.0 -0.53 195060.0 -102000.0 -0.59 -0.7959 -0.9985 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K15 mock treatment 358560.0 5910.0 0.03 279520.0 -17800.0 -0.1 -0.0495 -0.4563 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K16 mock treatment 351050.0 -1600.0 -0.01 362560.0 65200.0 0.38 0.2611 0.6901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K17 compound treatment 382440.0 29800.0 0.17 256890.0 -40400.0 -0.23 -0.0473 -0.1639 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K18 compound treatment 335800.0 -16900.0 -0.09 189600.0 -108000.0 -0.62 -0.5089 -0.8052 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K19 compound treatment 231040.0 -122000.0 -0.68 324890.0 27600.0 0.16 -0.3711 -0.5279 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K20 compound treatment 214510.0 -138000.0 -0.78 232840.0 -64500.0 -0.37 -0.8144 -0.9437 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K21 compound treatment 372400.0 19700.0 0.11 250620.0 -46700.0 -0.27 -0.1129 -0.3857 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K22 compound treatment 287150.0 -65500.0 -0.37 185980.0 -111000.0 -0.65 -0.7174 -0.9647 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K23 mock treatment 450260.0 97600.0 0.55 289850.0 -7480.0 -0.04 0.3579 0.6492 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 K24 mock treatment 434800.0 82100.0 0.46 415490.0 118000.0 0.69 0.8115 0.9817 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L01 compound treatment 172600.0 -180000.0 -1.01 189790.0 -108000.0 -0.62 -1.1577 -0.9728 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L02 compound treatment 249410.0 -103000.0 -0.58 331090.0 33800.0 0.2 -0.2725 -0.4444 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L03 compound treatment 88530.0 -264000.0 -1.49 58470.0 -239000.0 -1.39 -2.0309 -0.9994 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L04 compound treatment 287170.0 -65500.0 -0.37 299210.0 1880.0 0.01 -0.253 -0.6859 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L05 compound treatment 199560.0 -153000.0 -0.86 270420.0 -26900.0 -0.16 -0.7198 -0.8218 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L06 compound treatment 329210.0 -23400.0 -0.13 172750.0 -125000.0 -0.72 -0.6042 -0.8226 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L07 mock treatment 437860.0 85200.0 0.48 327630.0 30300.0 0.18 0.4634 0.9072 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L08 mock treatment 407620.0 55000.0 0.31 393120.0 95800.0 0.56 0.6116 0.9618 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L09 compound treatment 337390.0 -15300.0 -0.09 348800.0 51500.0 0.3 0.1503 0.4839 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L10 compound treatment 407300.0 54600.0 0.31 267060.0 -30300.0 -0.18 0.0934 0.2637 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L11 compound treatment 430250.0 77600.0 0.44 322820.0 25500.0 0.15 0.4134 0.8964 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L12 compound treatment 316400.0 -36300.0 -0.2 238200.0 -59100.0 -0.34 -0.3868 -0.9693 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L13 compound treatment 381290.0 28600.0 0.16 235360.0 -62000.0 -0.36 -0.1401 -0.3558 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L14 compound treatment 412320.0 59700.0 0.34 331960.0 34600.0 0.2 0.3795 0.9698 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L15 mock treatment 342140.0 -10500.0 -0.06 359460.0 62100.0 0.36 0.2129 0.5832 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L16 mock treatment 403360.0 50700.0 0.29 364710.0 67400.0 0.39 0.4782 0.9881 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L17 compound treatment 448070.0 95400.0 0.54 336800.0 39500.0 0.23 0.5417 0.9277 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L18 compound treatment 390970.0 38300.0 0.22 246400.0 -50900.0 -0.3 -0.0563 -0.154 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L19 compound treatment 310370.0 -42300.0 -0.24 219210.0 -78100.0 -0.45 -0.4887 -0.9548 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L20 compound treatment 249820.0 -103000.0 -0.58 217460.0 -79900.0 -0.46 -0.7369 -0.9939 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L21 compound treatment 407890.0 55200.0 0.31 317070.0 19700.0 0.11 0.3008 0.9078 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L22 compound treatment 375970.0 23300.0 0.13 206140.0 -91200.0 -0.53 -0.2811 -0.5159 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L23 mock treatment 349070.0 -3580.0 -0.02 308360.0 11000.0 0.06 0.031 0.4618 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 L24 mock treatment 412320.0 59700.0 0.34 195200.0 -102000.0 -0.59 -0.1813 -0.2663 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M01 compound treatment 336120.0 -16500.0 -0.09 333510.0 36200.0 0.21 0.0826 0.3597 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M02 compound treatment 415680.0 63000.0 0.35 371840.0 74500.0 0.43 0.5564 0.9952 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M03 compound treatment 344610.0 -8040.0 -0.05 224820.0 -72500.0 -0.42 -0.3294 -0.7787 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M04 compound treatment 197010.0 -156000.0 -0.88 209030.0 -88300.0 -0.51 -0.9817 -0.9673 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M05 compound treatment 409490.0 56800.0 0.32 340960.0 43600.0 0.25 0.4052 0.9932 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M06 compound treatment 419210.0 66600.0 0.37 206620.0 -90700.0 -0.53 -0.107 -0.1657 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M07 compound treatment 342520.0 -10100.0 -0.06 215040.0 -82300.0 -0.48 -0.3778 -0.786 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M08 compound treatment 261030.0 -91600.0 -0.52 240210.0 -57100.0 -0.33 -0.599 -0.9771 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M09 mock treatment 385120.0 32500.0 0.18 346580.0 49200.0 0.29 0.3312 0.9767 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M10 mock treatment 357180.0 4530.0 0.03 384750.0 87400.0 0.51 0.3765 0.7417 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M11 compound treatment 209070.0 -144000.0 -0.81 218910.0 -78400.0 -0.45 -0.8931 -0.963 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M12 compound treatment 172040.0 -181000.0 -1.02 107840.0 -189000.0 -1.1 -1.496 -0.9992 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M13 mock treatment 444230.0 91600.0 0.52 291390.0 -5940.0 -0.03 0.3402 0.6584 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M14 mock treatment 408480.0 55800.0 0.31 204110.0 -93200.0 -0.54 -0.1601 -0.2559 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M15 compound treatment 413040.0 60400.0 0.34 290450.0 -6880.0 -0.04 0.2122 0.6198 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M16 compound treatment 408800.0 56100.0 0.32 323760.0 26400.0 0.15 0.3319 0.9448 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M17 compound treatment 216800.0 -136000.0 -0.76 214930.0 -82400.0 -0.48 -0.8787 -0.9744 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M18 compound treatment 394320.0 41700.0 0.23 289330.0 -8000.0 -0.05 0.1331 0.5564 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M19 compound treatment 11260.0 -341000.0 -1.92 29150.0 -268000.0 -1.56 -2.4587 -0.9945 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M20 compound treatment 330240.0 -22400.0 -0.13 229460.0 -67900.0 -0.39 -0.3675 -0.8892 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M21 compound treatment 189310.0 -163000.0 -0.92 183480.0 -114000.0 -0.66 -1.1171 -0.9868 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M22 compound treatment 277170.0 -75500.0 -0.42 190930.0 -106000.0 -0.62 -0.7368 -0.9834 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M23 compound treatment 312010.0 -40600.0 -0.23 235240.0 -62100.0 -0.36 -0.4164 -0.976 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 M24 compound treatment 288540.0 -64100.0 -0.36 235860.0 -61500.0 -0.36 -0.5073 -1.0 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N01 compound treatment 361030.0 8380.0 0.05 397310.0 100000.0 0.58 0.4433 0.7621 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N02 compound treatment 278080.0 -74600.0 -0.42 379270.0 81900.0 0.48 0.0392 0.0618 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N03 compound treatment 363040.0 10400.0 0.06 238560.0 -58800.0 -0.34 -0.1997 -0.5773 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N04 compound treatment 222030.0 -131000.0 -0.74 341690.0 44400.0 0.26 -0.3381 -0.434 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N05 compound treatment 243840.0 -109000.0 -0.61 265520.0 -31800.0 -0.18 -0.5636 -0.881 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N06 compound treatment 352640.0 -10.3 0.0 286110.0 -11200.0 -0.07 -0.0461 -0.7077 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N07 compound treatment 309210.0 -43400.0 -0.24 237280.0 -60100.0 -0.35 -0.4192 -0.985 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N08 compound treatment 225460.0 -127000.0 -0.72 301120.0 3790.0 0.02 -0.4908 -0.6851 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N09 mock treatment 448110.0 95500.0 0.54 329770.0 32400.0 0.19 0.513 0.901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N10 mock treatment 405920.0 53300.0 0.3 293880.0 -3450.0 -0.02 0.1979 0.6584 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N11 compound treatment 331880.0 -20800.0 -0.12 189380.0 -108000.0 -0.63 -0.5254 -0.8249 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N12 compound treatment 280100.0 -72600.0 -0.41 190600.0 -107000.0 -0.62 -0.7265 -0.9796 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N13 mock treatment 371600.0 18900.0 0.11 200070.0 -97300.0 -0.56 -0.3234 -0.5634 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N14 mock treatment 334150.0 -18500.0 -0.1 306290.0 8960.0 0.05 -0.0369 -0.3172 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N15 compound treatment 327540.0 -25100.0 -0.14 270400.0 -26900.0 -0.16 -0.2104 -0.9988 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N16 compound treatment 285710.0 -66900.0 -0.38 314920.0 17600.0 0.1 -0.1943 -0.4978 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N17 compound treatment 313660.0 -39000.0 -0.22 252120.0 -45200.0 -0.26 -0.3406 -0.9961 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N18 compound treatment 304130.0 -48500.0 -0.27 249240.0 -48100.0 -0.28 -0.3904 -0.9999 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N19 compound treatment 453280.0 101000.0 0.57 187770.0 -110000.0 -0.64 -0.0487 -0.0572 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N20 compound treatment 337620.0 -15000.0 -0.08 269880.0 -27500.0 -0.16 -0.1724 -0.9562 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N21 compound treatment 297050.0 -55600.0 -0.31 259150.0 -38200.0 -0.22 -0.3779 -0.9856 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N22 compound treatment 317520.0 -35100.0 -0.2 194080.0 -103000.0 -0.6 -0.5633 -0.8932 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N23 compound treatment 372350.0 19700.0 0.11 254880.0 -42500.0 -0.25 -0.0957 -0.3543 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 N24 compound treatment 290330.0 -62300.0 -0.35 304510.0 7180.0 0.04 -0.2186 -0.6189 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O01 compound treatment 325980.0 -26700.0 -0.15 319070.0 21700.0 0.13 -0.017 -0.0869 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O02 compound treatment 265680.0 -87000.0 -0.49 254680.0 -42700.0 -0.25 -0.5211 -0.95 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O03 compound treatment 379520.0 26900.0 0.15 348100.0 50800.0 0.29 0.3151 0.9521 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O04 compound treatment 250450.0 -102000.0 -0.58 182560.0 -115000.0 -0.67 -0.8775 -0.9974 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O05 compound treatment 259520.0 -93100.0 -0.52 246240.0 -51100.0 -0.3 -0.5802 -0.9635 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O06 compound treatment 274310.0 -78300.0 -0.44 241690.0 -55600.0 -0.32 -0.54 -0.9882 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O07 compound treatment 456560.0 104000.0 0.58 280210.0 -17100.0 -0.1 0.3434 0.5788 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O08 compound treatment 362240.0 9590.0 0.05 307520.0 10200.0 0.06 0.0799 0.999 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O09 compound treatment 355580.0 2930.0 0.02 267890.0 -29400.0 -0.17 -0.1091 -0.6359 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O10 compound treatment 319240.0 -33400.0 -0.19 316110.0 18800.0 0.11 -0.056 -0.2577 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O11 mock treatment 450660.0 98000.0 0.55 329860.0 32500.0 0.19 0.5235 0.8978 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O12 mock treatment 356030.0 3380.0 0.02 291540.0 -5790.0 -0.03 -0.0103 -0.2669 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O13 compound treatment 345520.0 -7130.0 -0.04 272570.0 -24800.0 -0.14 -0.1299 -0.8713 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O14 compound treatment 293920.0 -58700.0 -0.33 224070.0 -73300.0 -0.42 -0.5342 -0.9923 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O15 compound treatment 374690.0 22000.0 0.12 266000.0 -31300.0 -0.18 -0.0408 -0.1852 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O16 compound treatment 264260.0 -88400.0 -0.5 238080.0 -59300.0 -0.34 -0.5948 -0.9837 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O17 compound treatment 286400.0 -66300.0 -0.37 230940.0 -66400.0 -0.39 -0.536 -0.9999 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O18 compound treatment 329370.0 -23300.0 -0.13 334420.0 37100.0 0.22 0.0594 0.2359 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O19 compound treatment 201090.0 -152000.0 -0.85 212500.0 -84800.0 -0.49 -0.9512 -0.9658 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O20 compound treatment 316060.0 -36600.0 -0.21 221010.0 -76300.0 -0.44 -0.4586 -0.9394 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O21 compound treatment 313390.0 -39300.0 -0.22 209370.0 -88000.0 -0.51 -0.517 -0.9299 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O22 compound treatment 238420.0 -114000.0 -0.64 179220.0 -118000.0 -0.68 -0.9391 -0.9995 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O23 compound treatment 177570.0 -175000.0 -0.99 141220.0 -156000.0 -0.91 -1.3371 -0.9991 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 O24 compound treatment 337340.0 -15300.0 -0.09 232020.0 -65300.0 -0.38 -0.3288 -0.8464 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P01 compound treatment 184960.0 -168000.0 -0.94 139900.0 -157000.0 -0.91 -1.3131 -0.9999 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P02 compound treatment 247040.0 -106000.0 -0.59 275860.0 -21500.0 -0.12 -0.5085 -0.8371 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P03 compound treatment 346760.0 -5890.0 -0.03 273340.0 -24000.0 -0.14 -0.1218 -0.8518 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P04 compound treatment 235040.0 -118000.0 -0.66 235840.0 -61500.0 -0.36 -0.7203 -0.9579 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P05 compound treatment 152810.0 -200000.0 -1.13 26640.0 -271000.0 -1.57 -1.9056 -0.9866 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P06 compound treatment 237510.0 -115000.0 -0.65 193870.0 -103000.0 -0.6 -0.8826 -0.9993 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P07 compound treatment 241440.0 -111000.0 -0.63 244700.0 -52600.0 -0.31 -0.6585 -0.9455 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P08 compound treatment 300270.0 -52400.0 -0.29 297000.0 -334.0 0.0 -0.2099 -0.7117 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P09 compound treatment 254460.0 -98200.0 -0.55 275680.0 -21700.0 -0.13 -0.4797 -0.8462 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P10 compound treatment 293310.0 -59300.0 -0.33 335860.0 38500.0 0.22 -0.0782 -0.1946 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P11 mock treatment 259440.0 -93200.0 -0.52 320670.0 23300.0 0.14 -0.2753 -0.5081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P12 mock treatment 270880.0 -81800.0 -0.46 299870.0 2540.0 0.01 -0.3151 -0.6842 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P13 compound treatment 314720.0 -37900.0 -0.21 232540.0 -64800.0 -0.38 -0.4167 -0.9641 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P14 compound treatment 233850.0 -119000.0 -0.67 256190.0 -41100.0 -0.24 -0.6416 -0.9036 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P15 compound treatment 231780.0 -121000.0 -0.68 236490.0 -60800.0 -0.35 -0.7307 -0.9532 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P16 compound treatment 280400.0 -72300.0 -0.41 220290.0 -77000.0 -0.45 -0.6035 -0.9989 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P17 compound treatment 242280.0 -110000.0 -0.62 275880.0 -21500.0 -0.12 -0.5273 -0.8322 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P18 compound treatment 59280.0 -293000.0 -1.65 41700.0 -256000.0 -1.48 -2.2161 -0.9985 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P19 compound treatment 203300.0 -149000.0 -0.84 243600.0 -53700.0 -0.31 -0.8149 -0.9088 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P20 compound treatment 287230.0 -65400.0 -0.37 220490.0 -76800.0 -0.45 -0.5755 -0.9955 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P21 compound treatment 262980.0 -89700.0 -0.5 245620.0 -51700.0 -0.3 -0.569 -0.9691 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P22 compound treatment 196880.0 -156000.0 -0.88 179040.0 -118000.0 -0.69 -1.1052 -0.9926 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P23 compound treatment 255410.0 -97200.0 -0.55 182050.0 -115000.0 -0.67 -0.8598 -0.9951 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2097 P24 compound treatment 205990.0 -147000.0 -0.83 144750.0 -153000.0 -0.88 -1.2095 -0.9994 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A01 compound treatment 439450.0 22000.0 0.12 461660.0 56000.0 0.32 0.3172 0.9125 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A02 compound treatment 385530.0 -31900.0 -0.18 388440.0 -17200.0 -0.1 -0.1977 -0.9613 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A03 compound treatment 450730.0 33300.0 0.19 315920.0 -89700.0 -0.52 -0.2355 -0.4259 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A04 compound treatment 406560.0 -10900.0 -0.06 473890.0 68300.0 0.4 0.2364 0.5903 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A05 compound treatment 315200.0 -102000.0 -0.58 229980.0 -176000.0 -1.02 -1.1275 -0.9635 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A06 compound treatment 194150.0 -223000.0 -1.26 318240.0 -87400.0 -0.51 -1.2474 -0.9202 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A07 compound treatment 197760.0 -220000.0 -1.24 146620.0 -259000.0 -1.5 -1.9368 -0.9953 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A08 compound treatment 231770.0 -186000.0 -1.05 235360.0 -170000.0 -0.99 -1.4375 -0.9996 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A09 compound treatment 429840.0 12400.0 0.07 255940.0 -150000.0 -0.87 -0.5647 -0.6483 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A10 compound treatment 272290.0 -145000.0 -0.82 417080.0 11400.0 0.07 -0.531 -0.6476 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A11 compound treatment 193800.0 -224000.0 -1.26 326720.0 -78900.0 -0.46 -1.214 -0.9061 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A12 compound treatment 359220.0 -58300.0 -0.33 453780.0 48100.0 0.28 -0.0345 -0.08 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A13 mock treatment 486270.0 68800.0 0.39 248660.0 -157000.0 -0.91 -0.3699 -0.3739 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A14 mock treatment 292120.0 -125000.0 -0.71 293720.0 -112000.0 -0.65 -0.9579 -0.9991 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A15 compound treatment 246400.0 -171000.0 -0.96 326890.0 -78700.0 -0.46 -1.0039 -0.9419 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A16 compound treatment 255650.0 -162000.0 -0.91 263920.0 -142000.0 -0.82 -1.2253 -0.9987 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A17 compound treatment 334270.0 -83200.0 -0.47 451550.0 45900.0 0.27 -0.1429 -0.2653 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A18 compound treatment 335040.0 -82400.0 -0.46 277210.0 -128000.0 -0.74 -0.8548 -0.9741 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A19 compound treatment 261050.0 -156000.0 -0.88 345600.0 -60000.0 -0.35 -0.8689 -0.9176 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A20 compound treatment 196480.0 -221000.0 -1.24 270890.0 -135000.0 -0.78 -1.4323 -0.9749 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A21 compound treatment 376770.0 -40700.0 -0.23 163580.0 -242000.0 -1.4 -1.1547 -0.8118 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A22 compound treatment 266500.0 -151000.0 -0.85 261210.0 -144000.0 -0.84 -1.1932 -1.0 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A23 compound treatment 284350.0 -133000.0 -0.75 187640.0 -218000.0 -1.26 -1.4239 -0.9688 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 A24 compound treatment 172180.0 -245000.0 -1.38 294140.0 -111000.0 -0.65 -1.4337 -0.9402 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B01 compound treatment 184760.0 -233000.0 -1.31 145040.0 -261000.0 -1.51 -1.995 -0.9975 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B02 compound treatment 423610.0 6140.0 0.03 505830.0 100000.0 0.58 0.4353 0.7478 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B03 compound treatment 428760.0 11300.0 0.06 522120.0 116000.0 0.68 0.5226 0.7702 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B04 compound treatment 303650.0 -114000.0 -0.64 487760.0 82100.0 0.48 -0.1163 -0.1457 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B05 compound treatment 519520.0 102000.0 0.57 543680.0 138000.0 0.8 0.9723 0.9868 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B06 compound treatment 385760.0 -31700.0 -0.18 298770.0 -107000.0 -0.62 -0.5645 -0.8752 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B07 compound treatment 393970.0 -23500.0 -0.13 307840.0 -97800.0 -0.57 -0.4946 -0.8493 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B08 compound treatment 344200.0 -73300.0 -0.41 282580.0 -123000.0 -0.71 -0.7963 -0.966 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B09 compound treatment 360000.0 -57500.0 -0.32 354450.0 -51200.0 -0.3 -0.4387 -0.9991 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B10 compound treatment 538920.0 121000.0 0.68 574850.0 169000.0 0.98 1.1773 0.9844 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B11 compound treatment 436340.0 18900.0 0.11 509480.0 104000.0 0.6 0.5009 0.8192 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B12 compound treatment 330420.0 -87100.0 -0.49 279450.0 -126000.0 -0.73 -0.864 -0.981 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B13 mock treatment 376330.0 -41100.0 -0.23 577280.0 172000.0 1.0 0.5401 0.5285 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B14 mock treatment 444960.0 27500.0 0.15 300330.0 -105000.0 -0.61 -0.3224 -0.5118 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B15 compound treatment 267600.0 -150000.0 -0.84 386140.0 -19500.0 -0.11 -0.6766 -0.7948 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B16 compound treatment 404090.0 -13400.0 -0.08 431310.0 25700.0 0.15 0.052 0.3117 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B17 compound treatment 340920.0 -76600.0 -0.43 417190.0 11600.0 0.07 -0.2574 -0.5901 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B18 compound treatment 321530.0 -95900.0 -0.54 490950.0 85300.0 0.49 -0.0321 -0.0438 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B19 compound treatment 289440.0 -128000.0 -0.72 534660.0 129000.0 0.75 0.0194 0.0187 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B20 compound treatment 200540.0 -217000.0 -1.22 145970.0 -260000.0 -1.51 -1.9284 -0.9946 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B21 compound treatment 305440.0 -112000.0 -0.63 406840.0 1200.0 0.01 -0.441 -0.6993 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B22 compound treatment 301780.0 -116000.0 -0.65 284410.0 -121000.0 -0.7 -0.9577 -0.9993 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B23 compound treatment 454640.0 37200.0 0.21 448120.0 42500.0 0.25 0.3222 0.9967 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 B24 compound treatment 274720.0 -143000.0 -0.8 413620.0 7980.0 0.05 -0.5355 -0.6653 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C01 compound treatment 467360.0 49900.0 0.28 333160.0 -72500.0 -0.42 -0.0986 -0.1951 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C02 compound treatment 390840.0 -26600.0 -0.15 245380.0 -160000.0 -0.93 -0.7632 -0.8107 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C03 compound treatment 301020.0 -116000.0 -0.66 461640.0 56000.0 0.32 -0.2339 -0.3197 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C04 compound treatment 245120.0 -172000.0 -0.97 260600.0 -145000.0 -0.84 -1.2809 -0.9975 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C05 compound treatment 339840.0 -77600.0 -0.44 309870.0 -95800.0 -0.56 -0.7018 -0.993 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C06 compound treatment 331590.0 -85900.0 -0.48 311160.0 -94500.0 -0.55 -0.7293 -0.9981 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C07 compound treatment 392440.0 -25000.0 -0.14 372700.0 -32900.0 -0.19 -0.2347 -0.9888 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C08 compound treatment 265010.0 -152000.0 -0.86 308610.0 -97000.0 -0.56 -1.0048 -0.979 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C09 compound treatment 197230.0 -220000.0 -1.24 281210.0 -124000.0 -0.72 -1.387 -0.9668 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C10 compound treatment 175570.0 -242000.0 -1.36 192800.0 -213000.0 -1.23 -1.8357 -0.9988 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C11 mock treatment 274770.0 -143000.0 -0.8 239520.0 -166000.0 -0.96 -1.2493 -0.9959 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C12 mock treatment 362280.0 -55200.0 -0.31 422150.0 16500.0 0.1 -0.152 -0.4675 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C13 compound treatment 174640.0 -243000.0 -1.37 206900.0 -199000.0 -1.15 -1.7816 -0.9964 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C14 compound treatment 420230.0 2760.0 0.02 399550.0 -6090.0 -0.04 -0.014 -0.3628 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C15 mock treatment 372910.0 -44600.0 -0.25 295300.0 -110000.0 -0.64 -0.6299 -0.9164 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C16 mock treatment 284800.0 -133000.0 -0.75 392820.0 -12800.0 -0.07 -0.5807 -0.7737 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C17 compound treatment 380810.0 -36700.0 -0.21 392160.0 -13500.0 -0.08 -0.2012 -0.9117 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C18 compound treatment 265670.0 -152000.0 -0.85 319210.0 -86400.0 -0.5 -0.9587 -0.9677 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C19 compound treatment 238040.0 -179000.0 -1.01 279360.0 -126000.0 -0.73 -1.2321 -0.9875 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C20 compound treatment 310820.0 -107000.0 -0.6 333770.0 -71900.0 -0.42 -0.7193 -0.9841 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C21 compound treatment 251480.0 -166000.0 -0.93 239360.0 -166000.0 -0.96 -1.3426 -0.9999 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C22 compound treatment 338910.0 -78600.0 -0.44 385600.0 -20000.0 -0.12 -0.3949 -0.8636 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C23 compound treatment 219490.0 -198000.0 -1.11 269560.0 -136000.0 -0.79 -1.3461 -0.9857 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 C24 compound treatment 259080.0 -158000.0 -0.89 376640.0 -29000.0 -0.17 -0.7494 -0.8259 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D01 compound treatment 292050.0 -125000.0 -0.71 409760.0 4120.0 0.02 -0.4824 -0.6828 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D02 compound treatment 254090.0 -163000.0 -0.92 301280.0 -104000.0 -0.61 -1.0783 -0.9794 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D03 compound treatment 448320.0 30800.0 0.17 305150.0 -100000.0 -0.58 -0.2893 -0.4757 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D04 compound treatment 252450.0 -165000.0 -0.93 407140.0 1500.0 0.01 -0.6507 -0.7005 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D05 compound treatment 334600.0 -82900.0 -0.47 230080.0 -176000.0 -1.02 -1.0498 -0.9374 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D06 compound treatment 183890.0 -234000.0 -1.31 185890.0 -220000.0 -1.27 -1.831 -0.9999 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D07 compound treatment 297030.0 -120000.0 -0.68 324610.0 -81000.0 -0.47 -0.8117 -0.984 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D08 compound treatment 259860.0 -158000.0 -0.89 404580.0 -1060.0 -0.01 -0.6317 -0.712 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D09 compound treatment 421850.0 4380.0 0.02 483680.0 78000.0 0.45 0.3375 0.7445 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D10 compound treatment 217840.0 -200000.0 -1.12 245290.0 -160000.0 -0.93 -1.4522 -0.9956 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D11 mock treatment 345630.0 -71800.0 -0.4 524380.0 119000.0 0.69 0.201 0.2516 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D12 mock treatment 425160.0 7690.0 0.04 447970.0 42300.0 0.25 0.2042 0.8191 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D13 compound treatment 437700.0 20200.0 0.11 358400.0 -47200.0 -0.27 -0.1132 -0.3815 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D14 compound treatment 378090.0 -39400.0 -0.22 402360.0 -3280.0 -0.02 -0.1702 -0.765 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D15 mock treatment 528020.0 111000.0 0.62 543810.0 138000.0 0.8 1.0067 0.9922 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D16 mock treatment 326910.0 -90600.0 -0.51 423480.0 17800.0 0.1 -0.2873 -0.5523 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D17 compound treatment 305780.0 -112000.0 -0.63 391400.0 -14200.0 -0.08 -0.503 -0.7932 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D18 compound treatment 394770.0 -22700.0 -0.13 411050.0 5410.0 0.03 -0.0682 -0.5181 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D19 compound treatment 282250.0 -135000.0 -0.76 407330.0 1690.0 0.01 -0.5313 -0.6979 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D20 compound treatment 275360.0 -142000.0 -0.8 424040.0 18400.0 0.11 -0.4902 -0.6074 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D21 compound treatment 300640.0 -117000.0 -0.66 314460.0 -91200.0 -0.53 -0.839 -0.9941 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D22 compound treatment 290970.0 -127000.0 -0.71 394670.0 -11000.0 -0.06 -0.5485 -0.7672 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D23 compound treatment 286110.0 -131000.0 -0.74 405120.0 -519.0 0.0 -0.525 -0.71 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 D24 compound treatment 302980.0 -114000.0 -0.64 367780.0 -37900.0 -0.22 -0.611 -0.8973 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E01 mock treatment 358000.0 -59500.0 -0.33 300070.0 -106000.0 -0.61 -0.6697 -0.9597 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E02 mock treatment 244960.0 -173000.0 -0.97 516320.0 111000.0 0.64 -0.2328 -0.2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E03 compound treatment 324350.0 -93100.0 -0.52 383520.0 -22100.0 -0.13 -0.4614 -0.8549 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E04 compound treatment 530430.0 113000.0 0.64 314190.0 -91400.0 -0.53 0.0746 0.0901 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E05 compound treatment 505760.0 88300.0 0.5 401490.0 -4150.0 -0.02 0.3344 0.6721 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E06 compound treatment 313170.0 -104000.0 -0.59 402500.0 -3140.0 -0.02 -0.4281 -0.7287 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E07 compound treatment 334100.0 -83400.0 -0.47 404960.0 -679.0 0.0 -0.3347 -0.713 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E08 compound treatment 396770.0 -20700.0 -0.12 338910.0 -66700.0 -0.39 -0.3561 -0.881 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E09 mock treatment 295260.0 -122000.0 -0.69 517250.0 112000.0 0.65 -0.0288 -0.0305 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E10 mock treatment 524930.0 107000.0 0.6 408930.0 3290.0 0.02 0.4412 0.7291 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E11 compound treatment 346930.0 -70500.0 -0.4 483540.0 77900.0 0.45 0.0386 0.0643 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E12 compound treatment 96550.0 -321000.0 -1.81 122270.0 -283000.0 -1.64 -2.4395 -0.9989 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E13 compound treatment 305090.0 -112000.0 -0.63 279710.0 -126000.0 -0.73 -0.9638 -0.9974 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E14 compound treatment 410240.0 -7230.0 -0.04 383060.0 -22600.0 -0.13 -0.1214 -0.8852 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E15 compound treatment 340720.0 -76800.0 -0.43 344130.0 -61500.0 -0.36 -0.5578 -0.9955 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E16 compound treatment 441890.0 24400.0 0.14 396330.0 -9310.0 -0.05 0.059 0.3997 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E17 mock treatment 405280.0 -12200.0 -0.07 495530.0 89900.0 0.52 0.3201 0.6088 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E18 mock treatment 490490.0 73000.0 0.41 487270.0 81600.0 0.47 0.6254 0.9975 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E19 compound treatment 223960.0 -194000.0 -1.09 214140.0 -191000.0 -1.11 -1.5556 -1.0 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E20 compound treatment 290740.0 -127000.0 -0.71 329290.0 -76300.0 -0.44 -0.8176 -0.9737 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E21 compound treatment 384450.0 -33000.0 -0.19 386340.0 -19300.0 -0.11 -0.2106 -0.9705 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E22 compound treatment 345530.0 -71900.0 -0.41 378240.0 -27400.0 -0.16 -0.3987 -0.9165 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E23 compound treatment 276320.0 -141000.0 -0.79 287320.0 -118000.0 -0.69 -1.0471 -0.9973 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 E24 compound treatment 312600.0 -105000.0 -0.59 448010.0 42400.0 0.25 -0.2437 -0.3811 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F01 mock treatment 469180.0 51700.0 0.29 347200.0 -58400.0 -0.34 -0.0338 -0.0757 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F02 mock treatment 171550.0 -246000.0 -1.38 222650.0 -183000.0 -1.06 -1.7293 -0.9914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F03 compound treatment 518750.0 101000.0 0.57 250790.0 -155000.0 -0.9 -0.2319 -0.218 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F04 compound treatment 287620.0 -130000.0 -0.73 314840.0 -90800.0 -0.53 -0.8893 -0.987 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F05 compound treatment 209560.0 -208000.0 -1.17 381120.0 -24500.0 -0.14 -0.9282 -0.7872 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F06 compound treatment 272400.0 -145000.0 -0.82 488530.0 82900.0 0.48 -0.2376 -0.2507 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F07 compound treatment 270740.0 -147000.0 -0.83 342790.0 -62800.0 -0.36 -0.8418 -0.9324 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F08 compound treatment 263970.0 -154000.0 -0.86 400220.0 -5420.0 -0.03 -0.6333 -0.7323 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F09 mock treatment 289060.0 -128000.0 -0.72 412750.0 7110.0 0.04 -0.482 -0.6657 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F10 mock treatment 516860.0 99400.0 0.56 400660.0 -4980.0 -0.03 0.3752 0.6697 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F11 compound treatment 386760.0 -30700.0 -0.17 404390.0 -1250.0 -0.01 -0.1274 -0.7361 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F12 compound treatment 439040.0 21600.0 0.12 329980.0 -75700.0 -0.44 -0.2244 -0.4929 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F13 compound treatment 425060.0 7590.0 0.04 515080.0 109000.0 0.63 0.479 0.753 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F14 compound treatment 336910.0 -80600.0 -0.45 487640.0 82000.0 0.48 0.0156 0.0237 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F15 compound treatment 271370.0 -146000.0 -0.82 286520.0 -119000.0 -0.69 -1.0701 -0.9962 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F16 compound treatment 283610.0 -134000.0 -0.75 296800.0 -109000.0 -0.63 -0.9792 -0.9961 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F17 mock treatment 387650.0 -29800.0 -0.17 428890.0 23300.0 0.13 -0.0234 -0.1085 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F18 mock treatment 395770.0 -21700.0 -0.12 466240.0 60600.0 0.35 0.1621 0.4357 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F19 compound treatment 229150.0 -188000.0 -1.06 279870.0 -126000.0 -0.73 -1.2654 -0.9833 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F20 compound treatment 397640.0 -19800.0 -0.11 326990.0 -78600.0 -0.46 -0.4015 -0.8549 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F21 compound treatment 268180.0 -149000.0 -0.84 348380.0 -57300.0 -0.33 -0.8291 -0.9175 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F22 compound treatment 367460.0 -50000.0 -0.28 307680.0 -98000.0 -0.57 -0.6008 -0.9476 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F23 compound treatment 232640.0 -185000.0 -1.04 161010.0 -245000.0 -1.42 -1.7389 -0.9884 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 F24 compound treatment 274330.0 -143000.0 -0.81 462800.0 57200.0 0.33 -0.3354 -0.3849 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G01 compound treatment 211630.0 -206000.0 -1.16 294240.0 -111000.0 -0.65 -1.2762 -0.9619 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G02 compound treatment 320650.0 -96800.0 -0.55 398340.0 -7300.0 -0.04 -0.4154 -0.7597 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G03 mock treatment 504030.0 86600.0 0.49 247010.0 -159000.0 -0.92 -0.306 -0.2939 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G04 mock treatment 247150.0 -170000.0 -0.96 498130.0 92500.0 0.54 -0.2987 -0.2719 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G05 compound treatment 457030.0 39600.0 0.22 361830.0 -43800.0 -0.25 -0.0222 -0.0657 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G06 compound treatment 103840.0 -314000.0 -1.77 88960.0 -317000.0 -1.84 -2.5471 -0.9998 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G07 compound treatment 300730.0 -117000.0 -0.66 261550.0 -144000.0 -0.84 -1.0556 -0.9929 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G08 compound treatment 266000.0 -151000.0 -0.85 217780.0 -188000.0 -1.09 -1.3733 -0.9927 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G09 compound treatment 325310.0 -92200.0 -0.52 514450.0 109000.0 0.63 0.0793 0.0971 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G10 compound treatment 267270.0 -150000.0 -0.85 456250.0 50600.0 0.29 -0.3904 -0.4361 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G11 compound treatment 14280.0 -403000.0 -2.27 14330.0 -391000.0 -2.27 -3.2097 -1.0 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G12 compound treatment 286160.0 -131000.0 -0.74 357990.0 -47600.0 -0.28 -0.7181 -0.9099 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G13 compound treatment 507280.0 89800.0 0.51 579040.0 173000.0 1.01 1.0686 0.9494 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G14 compound treatment 292030.0 -125000.0 -0.71 359760.0 -45900.0 -0.27 -0.6875 -0.911 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G15 compound treatment 498840.0 81400.0 0.46 536170.0 131000.0 0.76 0.8592 0.971 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G16 compound treatment 379550.0 -37900.0 -0.21 379690.0 -25900.0 -0.15 -0.2574 -0.9854 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G17 compound treatment 243210.0 -174000.0 -0.98 191810.0 -214000.0 -1.24 -1.5706 -0.9933 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G18 compound treatment 373770.0 -43700.0 -0.25 325200.0 -80400.0 -0.47 -0.5038 -0.9553 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G19 mock treatment 267070.0 -150000.0 -0.85 488250.0 82600.0 0.48 -0.2599 -0.2672 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G20 mock treatment 318880.0 -98600.0 -0.56 314570.0 -91100.0 -0.53 -0.7659 -0.9997 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G21 compound treatment 259880.0 -158000.0 -0.89 334160.0 -71500.0 -0.41 -0.9204 -0.94 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G22 compound treatment 315640.0 -102000.0 -0.57 405080.0 -559.0 0.0 -0.4077 -0.7111 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G23 compound treatment 273360.0 -144000.0 -0.81 334970.0 -70700.0 -0.41 -0.8635 -0.95 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 G24 compound treatment 284480.0 -133000.0 -0.75 435940.0 30300.0 0.18 -0.4051 -0.5268 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H01 compound treatment 244240.0 -173000.0 -0.98 296410.0 -109000.0 -0.63 -1.1375 -0.9782 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H02 compound treatment 426890.0 9420.0 0.05 223320.0 -182000.0 -1.06 -0.7102 -0.6708 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H03 mock treatment 538560.0 121000.0 0.68 502900.0 97300.0 0.56 0.8809 0.9956 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H04 mock treatment 379360.0 -38100.0 -0.21 325760.0 -79900.0 -0.46 -0.4793 -0.9388 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H05 compound treatment 292010.0 -125000.0 -0.71 449070.0 43400.0 0.25 -0.3213 -0.4285 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H06 compound treatment 512250.0 94800.0 0.53 327960.0 -77700.0 -0.45 0.0587 0.0841 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H07 compound treatment 318510.0 -99000.0 -0.56 411260.0 5620.0 0.03 -0.3709 -0.6646 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H08 compound treatment 502720.0 85200.0 0.48 494840.0 89200.0 0.52 0.7051 0.9993 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H09 compound treatment 500660.0 83200.0 0.47 440340.0 34700.0 0.2 0.4734 0.9288 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H10 compound treatment 389830.0 -27600.0 -0.16 482040.0 76400.0 0.44 0.2033 0.4328 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H11 compound treatment 216560.0 -201000.0 -1.13 439840.0 34200.0 0.2 -0.6595 -0.5743 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H12 compound treatment 274190.0 -143000.0 -0.81 297600.0 -108000.0 -0.63 -1.0134 -0.9922 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H13 compound treatment 440690.0 23200.0 0.13 491110.0 85500.0 0.5 0.4429 0.864 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H14 compound treatment 504410.0 86900.0 0.49 447960.0 42300.0 0.25 0.5196 0.9491 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H15 compound treatment 437440.0 20000.0 0.11 340190.0 -65400.0 -0.38 -0.1889 -0.4772 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H16 compound treatment 268170.0 -149000.0 -0.84 327360.0 -78300.0 -0.45 -0.9153 -0.9582 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H17 compound treatment 332710.0 -84800.0 -0.48 357020.0 -48600.0 -0.28 -0.5368 -0.9685 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H18 compound treatment 390970.0 -26500.0 -0.15 429920.0 24300.0 0.14 -0.0059 -0.0289 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H19 mock treatment 439630.0 22200.0 0.12 360880.0 -44800.0 -0.26 -0.0953 -0.3311 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H20 mock treatment 362240.0 -55200.0 -0.31 465440.0 59800.0 0.35 0.0254 0.0545 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H21 compound treatment 318790.0 -98700.0 -0.56 404690.0 -949.0 -0.01 -0.3967 -0.7141 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H22 compound treatment 333280.0 -84200.0 -0.47 353440.0 -52200.0 -0.3 -0.5492 -0.9765 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H23 compound treatment 289160.0 -128000.0 -0.72 332400.0 -73200.0 -0.42 -0.8111 -0.968 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 H24 compound treatment 342300.0 -75200.0 -0.42 381980.0 -23700.0 -0.14 -0.3963 -0.8907 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I01 compound treatment 221870.0 -196000.0 -1.1 302240.0 -103000.0 -0.6 -1.2026 -0.9592 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I02 compound treatment 478610.0 61100.0 0.34 360390.0 -45200.0 -0.26 0.0578 0.1336 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I03 compound treatment 203310.0 -214000.0 -1.21 228520.0 -177000.0 -1.03 -1.5788 -0.9968 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I04 compound treatment 307200.0 -110000.0 -0.62 267220.0 -138000.0 -0.8 -1.0066 -0.9919 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I05 mock treatment 375270.0 -42200.0 -0.24 230650.0 -175000.0 -1.01 -0.8856 -0.8497 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I06 mock treatment 443070.0 25600.0 0.14 472250.0 66600.0 0.39 0.3751 0.9096 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I07 compound treatment 538360.0 121000.0 0.68 288180.0 -117000.0 -0.68 -5.0E-4 -5.0E-4 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I08 compound treatment 348380.0 -69100.0 -0.39 332590.0 -73000.0 -0.42 -0.5746 -0.9991 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I09 compound treatment 343740.0 -73700.0 -0.42 299850.0 -106000.0 -0.61 -0.7273 -0.9819 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I10 compound treatment 307220.0 -110000.0 -0.62 450600.0 45000.0 0.26 -0.2545 -0.378 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I11 compound treatment 351740.0 -65700.0 -0.37 302590.0 -103000.0 -0.6 -0.6842 -0.9734 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I12 compound treatment 418440.0 968.0 0.01 349290.0 -56300.0 -0.33 -0.2272 -0.6952 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I13 compound treatment 462950.0 45500.0 0.26 474350.0 68700.0 0.4 0.4628 0.9771 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I14 compound treatment 299130.0 -118000.0 -0.67 320710.0 -84900.0 -0.49 -0.8194 -0.989 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I15 compound treatment 150780.0 -267000.0 -1.5 70760.0 -335000.0 -1.94 -2.4349 -0.9919 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I16 compound treatment 333410.0 -84100.0 -0.47 321440.0 -84200.0 -0.49 -0.6799 -0.9999 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I17 compound treatment 490270.0 72800.0 0.41 392600.0 -13000.0 -0.08 0.2363 0.5671 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I18 compound treatment 266160.0 -151000.0 -0.85 367650.0 -38000.0 -0.22 -0.7581 -0.8616 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I19 compound treatment 386300.0 -31200.0 -0.18 494470.0 88800.0 0.52 0.2402 0.4413 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I20 compound treatment 385870.0 -31600.0 -0.18 424360.0 18700.0 0.11 -0.049 -0.2352 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I21 mock treatment 423360.0 5890.0 0.03 398560.0 -7080.0 -0.04 -0.0056 -0.106 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I22 mock treatment 442720.0 25200.0 0.14 453400.0 47800.0 0.28 0.2964 0.9519 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I23 compound treatment 369670.0 -47800.0 -0.27 291710.0 -114000.0 -0.66 -0.6575 -0.9216 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 I24 compound treatment 260160.0 -157000.0 -0.89 252930.0 -153000.0 -0.89 -1.2524 -1.0 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J01 compound treatment 174880.0 -243000.0 -1.37 291200.0 -114000.0 -0.66 -1.435 -0.9451 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J02 compound treatment 168930.0 -249000.0 -1.4 448400.0 42800.0 0.25 -0.814 -0.5729 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J03 compound treatment 220330.0 -197000.0 -1.11 344420.0 -61200.0 -0.36 -1.0358 -0.8889 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J04 compound treatment 277780.0 -140000.0 -0.79 486790.0 81200.0 0.47 -0.2233 -0.2436 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J05 mock treatment 525870.0 108000.0 0.61 285940.0 -120000.0 -0.69 -0.0594 -0.0642 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J06 mock treatment 510830.0 93400.0 0.53 248370.0 -157000.0 -0.91 -0.2733 -0.2596 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J07 compound treatment 313010.0 -104000.0 -0.59 318460.0 -87200.0 -0.51 -0.7733 -0.9972 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J08 compound treatment 285920.0 -132000.0 -0.74 215770.0 -190000.0 -1.1 -1.3023 -0.9814 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J09 compound treatment 289080.0 -128000.0 -0.72 257050.0 -149000.0 -0.86 -1.1204 -0.9962 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J10 compound treatment 339740.0 -77700.0 -0.44 389700.0 -15900.0 -0.09 -0.3748 -0.838 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J11 compound treatment 338240.0 -79200.0 -0.45 377840.0 -27800.0 -0.16 -0.4294 -0.9054 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J12 compound treatment 274560.0 -143000.0 -0.8 133230.0 -272000.0 -1.58 -1.686 -0.951 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J13 compound treatment 355710.0 -61800.0 -0.35 404230.0 -1410.0 -0.01 -0.2516 -0.7235 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J14 compound treatment 423120.0 5650.0 0.03 345500.0 -60100.0 -0.35 -0.2241 -0.64 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J15 compound treatment 261810.0 -156000.0 -0.88 220000.0 -186000.0 -1.08 -1.3809 -0.9948 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J16 compound treatment 423440.0 5970.0 0.03 312920.0 -92700.0 -0.54 -0.3565 -0.6616 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J17 compound treatment 439100.0 21600.0 0.12 369760.0 -35900.0 -0.21 -0.061 -0.2532 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J18 compound treatment 305030.0 -112000.0 -0.63 362930.0 -42700.0 -0.25 -0.6227 -0.9162 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J19 compound treatment 352000.0 -65500.0 -0.37 337440.0 -68200.0 -0.4 -0.5403 -0.9994 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J20 compound treatment 525460.0 108000.0 0.61 404840.0 -799.0 0.0 0.4266 0.7017 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J21 mock treatment 363610.0 -53900.0 -0.3 482130.0 76500.0 0.44 0.0993 0.1847 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J22 mock treatment 519230.0 102000.0 0.57 426020.0 20400.0 0.12 0.4886 0.8354 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J23 compound treatment 297630.0 -120000.0 -0.67 235160.0 -170000.0 -0.99 -1.1762 -0.9826 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 J24 compound treatment 419620.0 2150.0 0.01 310200.0 -95400.0 -0.55 -0.3828 -0.6915 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K01 compound treatment 499360.0 81900.0 0.46 460060.0 54400.0 0.32 0.5491 0.9829 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K02 compound treatment 490370.0 72900.0 0.41 383240.0 -22400.0 -0.13 0.1983 0.4607 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K03 compound treatment 485670.0 68200.0 0.38 198650.0 -207000.0 -1.2 -0.5774 -0.4581 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K04 compound treatment 416760.0 -712.0 0.0 401040.0 -4600.0 -0.03 -0.0217 -0.8044 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K05 compound treatment 206300.0 -211000.0 -1.19 65310.0 -340000.0 -1.97 -2.2362 -0.9706 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K06 compound treatment 526680.0 109000.0 0.61 327560.0 -78100.0 -0.45 0.1145 0.15 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K07 mock treatment 558040.0 141000.0 0.79 537460.0 132000.0 0.76 1.1001 0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K08 mock treatment 450750.0 33300.0 0.19 344590.0 -61000.0 -0.35 -0.1179 -0.2943 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K09 compound treatment 279600.0 -138000.0 -0.78 239910.0 -166000.0 -0.96 -1.2284 -0.9944 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K10 compound treatment 436160.0 18700.0 0.11 348130.0 -57500.0 -0.33 -0.1614 -0.4616 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K11 compound treatment 134350.0 -283000.0 -1.59 202280.0 -203000.0 -1.18 -1.961 -0.989 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K12 compound treatment 361680.0 -55800.0 -0.31 209810.0 -196000.0 -1.14 -1.0251 -0.87 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K13 compound treatment 388670.0 -28800.0 -0.16 366260.0 -39400.0 -0.23 -0.2761 -0.9859 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K14 compound treatment 288660.0 -129000.0 -0.73 297390.0 -108000.0 -0.63 -0.9567 -0.9974 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K15 mock treatment 468900.0 51400.0 0.29 505300.0 99700.0 0.58 0.6134 0.9489 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K16 mock treatment 314750.0 -103000.0 -0.58 576700.0 171000.0 0.99 0.2926 0.2548 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K17 compound treatment 369450.0 -48000.0 -0.27 439590.0 34000.0 0.2 -0.0519 -0.1553 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K18 compound treatment 423700.0 6230.0 0.04 326920.0 -78700.0 -0.46 -0.298 -0.6509 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K19 compound treatment 396160.0 -21300.0 -0.12 395260.0 -10400.0 -0.06 -0.1274 -0.9491 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K20 compound treatment 450990.0 33500.0 0.19 482630.0 77000.0 0.45 0.4491 0.9266 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K21 compound treatment 390140.0 -27300.0 -0.15 461290.0 55700.0 0.32 0.1194 0.334 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K22 compound treatment 340250.0 -77200.0 -0.43 311470.0 -94200.0 -0.55 -0.6936 -0.9936 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K23 mock treatment 465650.0 48200.0 0.27 398290.0 -7350.0 -0.04 0.1616 0.5888 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 K24 mock treatment 399270.0 -18200.0 -0.1 399400.0 -6240.0 -0.04 -0.098 -0.9022 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L01 compound treatment 442650.0 25200.0 0.14 290970.0 -115000.0 -0.67 -0.37 -0.5442 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L02 compound treatment 215000.0 -202000.0 -1.14 136980.0 -269000.0 -1.56 -1.9077 -0.9882 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L03 compound treatment 71700.0 -346000.0 -1.95 54970.0 -351000.0 -2.03 -2.8144 -0.9998 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L04 compound treatment 407860.0 -9610.0 -0.05 141760.0 -264000.0 -1.53 -1.1204 -0.7317 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L05 compound treatment 313640.0 -104000.0 -0.58 431380.0 25700.0 0.15 -0.3078 -0.5101 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L06 compound treatment 300330.0 -117000.0 -0.66 314330.0 -91300.0 -0.53 -0.8407 -0.9941 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L07 mock treatment 503390.0 85900.0 0.48 426350.0 20700.0 0.12 0.4269 0.8567 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L08 mock treatment 544760.0 127000.0 0.72 304440.0 -101000.0 -0.59 0.0917 0.099 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L09 compound treatment 487070.0 69600.0 0.39 407930.0 2290.0 0.01 0.2864 0.7307 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L10 compound treatment 392960.0 -24500.0 -0.14 324760.0 -80900.0 -0.47 -0.4292 -0.8779 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L11 compound treatment 208390.0 -209000.0 -1.18 207380.0 -198000.0 -1.15 -1.6453 -0.9999 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L12 compound treatment 470240.0 52800.0 0.3 485440.0 79800.0 0.46 0.5373 0.977 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L13 compound treatment 443530.0 26100.0 0.15 462200.0 56600.0 0.33 0.3357 0.9342 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L14 compound treatment 464290.0 46800.0 0.26 355270.0 -50400.0 -0.29 -0.0202 -0.0513 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L15 mock treatment 495200.0 77700.0 0.44 365660.0 -40000.0 -0.23 0.1455 0.2937 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L16 mock treatment 462450.0 45000.0 0.25 485450.0 79800.0 0.46 0.5063 0.9597 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L17 compound treatment 434150.0 16700.0 0.09 535250.0 130000.0 0.75 0.5979 0.7893 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L18 compound treatment 432290.0 14800.0 0.08 434340.0 28700.0 0.17 0.1767 0.949 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L19 compound treatment 366530.0 -50900.0 -0.29 394250.0 -11400.0 -0.07 -0.2495 -0.8478 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L20 compound treatment 412710.0 -4760.0 -0.03 396920.0 -8720.0 -0.05 -0.0547 -0.956 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L21 compound treatment 348690.0 -68800.0 -0.39 449440.0 43800.0 0.25 -0.0942 -0.2034 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L22 compound treatment 405980.0 -11500.0 -0.06 373310.0 -32300.0 -0.19 -0.1783 -0.8991 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L23 mock treatment 284360.0 -133000.0 -0.75 326410.0 -79200.0 -0.46 -0.8548 -0.9724 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 L24 mock treatment 416980.0 -492.0 0.0 470450.0 64800.0 0.38 0.2638 0.7019 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M01 compound treatment 396060.0 -21400.0 -0.12 362720.0 -42900.0 -0.25 -0.2612 -0.9446 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M02 compound treatment 237030.0 -180000.0 -1.02 345280.0 -60400.0 -0.35 -0.9658 -0.8989 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M03 compound treatment 297800.0 -120000.0 -0.67 269860.0 -136000.0 -0.79 -1.0332 -0.997 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M04 compound treatment 324650.0 -92800.0 -0.52 282970.0 -123000.0 -0.71 -0.8725 -0.9885 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M05 compound treatment 407840.0 -9630.0 -0.05 203010.0 -203000.0 -1.18 -0.8693 -0.7389 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M06 compound treatment 289600.0 -128000.0 -0.72 435810.0 30200.0 0.17 -0.3853 -0.5201 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M07 compound treatment 479860.0 62400.0 0.35 307130.0 -98500.0 -0.57 -0.1556 -0.2321 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M08 compound treatment 403690.0 -13800.0 -0.08 375470.0 -30200.0 -0.17 -0.1786 -0.933 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M09 mock treatment 481220.0 63700.0 0.36 449480.0 43800.0 0.25 0.4335 0.9858 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M10 mock treatment 441130.0 23700.0 0.13 331420.0 -74200.0 -0.43 -0.2102 -0.4665 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M11 compound treatment 260490.0 -157000.0 -0.88 240700.0 -165000.0 -0.96 -1.3013 -0.9992 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M12 compound treatment 308740.0 -109000.0 -0.61 375860.0 -29800.0 -0.17 -0.5549 -0.8725 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M13 mock treatment 472910.0 55400.0 0.31 418000.0 12400.0 0.07 0.2714 0.8475 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M14 mock treatment 463160.0 45700.0 0.26 400430.0 -5210.0 -0.03 0.1605 0.6198 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M15 compound treatment 451120.0 33600.0 0.19 392290.0 -13300.0 -0.08 0.0792 0.387 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M16 compound treatment 415650.0 -1820.0 -0.01 540800.0 135000.0 0.78 0.547 0.6978 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M17 compound treatment 341450.0 -76000.0 -0.43 316110.0 -89500.0 -0.52 -0.6698 -0.9954 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M18 compound treatment 362100.0 -55400.0 -0.31 360990.0 -44600.0 -0.26 -0.4035 -0.9957 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M19 compound treatment 380130.0 -37300.0 -0.21 361240.0 -44400.0 -0.26 -0.3307 -0.9949 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M20 compound treatment 337470.0 -80000.0 -0.45 373840.0 -31800.0 -0.18 -0.4489 -0.9223 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M21 compound treatment 322400.0 -95100.0 -0.54 456860.0 51200.0 0.3 -0.1684 -0.2751 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M22 compound treatment 300960.0 -117000.0 -0.66 431170.0 25500.0 0.15 -0.3591 -0.534 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M23 compound treatment 396690.0 -20800.0 -0.12 439270.0 33600.0 0.2 0.0552 0.2426 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 M24 compound treatment 349710.0 -67800.0 -0.38 340160.0 -65500.0 -0.38 -0.5383 -1.0 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N01 compound treatment 388570.0 -28900.0 -0.16 230150.0 -175000.0 -1.02 -0.8347 -0.8099 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N02 compound treatment 377920.0 -39600.0 -0.22 401950.0 -3690.0 -0.02 -0.1726 -0.7715 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N03 compound treatment 368960.0 -48500.0 -0.27 332570.0 -73100.0 -0.42 -0.4928 -0.9774 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N04 compound treatment 352890.0 -64600.0 -0.36 264020.0 -142000.0 -0.82 -0.8378 -0.9328 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N05 compound treatment 437600.0 20100.0 0.11 456370.0 50700.0 0.29 0.2882 0.914 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N06 compound treatment 408090.0 -9380.0 -0.05 320500.0 -85100.0 -0.49 -0.3865 -0.7783 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N07 compound treatment 482330.0 64900.0 0.37 511870.0 106000.0 0.62 0.6938 0.9688 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N08 compound treatment 494260.0 76800.0 0.43 337340.0 -68300.0 -0.4 0.0256 0.0436 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N09 mock treatment 466940.0 49500.0 0.28 505600.0 100000.0 0.58 0.6068 0.9436 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N10 mock treatment 491200.0 73700.0 0.42 409460.0 3820.0 0.02 0.3092 0.7438 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N11 compound treatment 352550.0 -64900.0 -0.37 282940.0 -123000.0 -0.71 -0.7616 -0.9521 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N12 compound treatment 469970.0 52500.0 0.3 526770.0 121000.0 0.7 0.7057 0.926 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N13 mock treatment 339890.0 -77600.0 -0.44 496930.0 91300.0 0.53 0.0655 0.0955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N14 mock treatment 456690.0 39200.0 0.22 381150.0 -24500.0 -0.14 0.0557 0.2121 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N15 compound treatment 411730.0 -5740.0 -0.03 423460.0 17800.0 0.1 0.0502 0.4638 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N16 compound treatment 432130.0 14700.0 0.08 544390.0 139000.0 0.8 0.6273 0.7756 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N17 compound treatment 377010.0 -40500.0 -0.23 405120.0 -519.0 0.0 -0.1632 -0.7164 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N18 compound treatment 392090.0 -25400.0 -0.14 228920.0 -177000.0 -1.02 -0.8257 -0.798 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N19 compound treatment 327200.0 -90300.0 -0.51 330890.0 -74700.0 -0.43 -0.6659 -0.9969 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N20 compound treatment 353180.0 -64300.0 -0.36 316060.0 -89600.0 -0.52 -0.6233 -0.9844 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N21 compound treatment 382630.0 -34800.0 -0.2 494270.0 88600.0 0.51 0.2248 0.4085 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N22 compound treatment 321890.0 -95600.0 -0.54 341760.0 -63900.0 -0.37 -0.6424 -0.9834 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N23 compound treatment 370240.0 -47200.0 -0.27 335720.0 -69900.0 -0.41 -0.4747 -0.9791 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 N24 compound treatment 222800.0 -195000.0 -1.1 197470.0 -208000.0 -1.21 -1.6286 -0.9988 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O01 compound treatment 411690.0 -5780.0 -0.03 354670.0 -51000.0 -0.3 -0.232 -0.7803 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O02 compound treatment 413960.0 -3510.0 -0.02 325630.0 -80000.0 -0.46 -0.3421 -0.7366 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O03 compound treatment 522370.0 105000.0 0.59 323320.0 -82300.0 -0.48 0.08 0.1053 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O04 compound treatment 270090.0 -147000.0 -0.83 248000.0 -158000.0 -0.91 -1.2331 -0.9988 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O05 compound treatment 290020.0 -127000.0 -0.72 324390.0 -81200.0 -0.47 -0.8405 -0.9792 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O06 compound treatment 333440.0 -84000.0 -0.47 446420.0 40800.0 0.24 -0.1673 -0.3163 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O07 compound treatment 534050.0 117000.0 0.66 342850.0 -62800.0 -0.36 0.2066 0.2752 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O08 compound treatment 267800.0 -150000.0 -0.84 242670.0 -163000.0 -0.95 -1.2641 -0.9984 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O09 compound treatment 283750.0 -134000.0 -0.75 353700.0 -51900.0 -0.3 -0.7453 -0.9192 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O10 compound treatment 273700.0 -144000.0 -0.81 364720.0 -40900.0 -0.24 -0.7401 -0.8775 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O11 mock treatment 522720.0 105000.0 0.59 413720.0 8080.0 0.05 0.4521 0.7607 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O12 mock treatment 319330.0 -98100.0 -0.55 491060.0 85400.0 0.5 -0.0404 -0.0544 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O13 compound treatment 472900.0 55400.0 0.31 479440.0 73800.0 0.43 0.5233 0.9879 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O14 compound treatment 279170.0 -138000.0 -0.78 348030.0 -57600.0 -0.33 -0.7868 -0.9286 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O15 compound treatment 436850.0 19400.0 0.11 548070.0 142000.0 0.83 0.6612 0.7936 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O16 compound treatment 297760.0 -120000.0 -0.67 404000.0 -1640.0 -0.01 -0.4833 -0.717 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O17 compound treatment 323770.0 -93700.0 -0.53 435250.0 29600.0 0.17 -0.2516 -0.4535 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O18 compound treatment 396880.0 -20600.0 -0.12 418590.0 13000.0 0.08 -0.0289 -0.209 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O19 compound treatment 265120.0 -152000.0 -0.86 315700.0 -89900.0 -0.52 -0.9753 -0.9716 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O20 compound treatment 358650.0 -58800.0 -0.33 265670.0 -140000.0 -0.81 -0.8081 -0.9218 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O21 compound treatment 432480.0 15000.0 0.08 480410.0 74800.0 0.43 0.3664 0.8293 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O22 compound treatment 264650.0 -153000.0 -0.86 292710.0 -113000.0 -0.65 -1.0714 -0.9909 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O23 compound treatment 352260.0 -65200.0 -0.37 373410.0 -32200.0 -0.19 -0.3918 -0.951 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 O24 compound treatment 403330.0 -14100.0 -0.08 445490.0 39900.0 0.23 0.1071 0.4382 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P01 compound treatment 75570.0 -342000.0 -1.92 66940.0 -339000.0 -1.96 -2.7499 -0.9999 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P02 compound treatment 73930.0 -344000.0 -1.93 91120.0 -315000.0 -1.82 -2.6573 -0.9996 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P03 compound treatment 315610.0 -102000.0 -0.57 312810.0 -92800.0 -0.54 -0.7862 -0.9995 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P04 compound treatment 273240.0 -144000.0 -0.81 218170.0 -187000.0 -1.09 -1.3429 -0.9897 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P05 compound treatment 200050.0 -217000.0 -1.22 313170.0 -92500.0 -0.54 -1.2447 -0.9314 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P06 compound treatment 162410.0 -255000.0 -1.44 216320.0 -189000.0 -1.1 -1.7917 -0.9912 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P07 compound treatment 449880.0 32400.0 0.18 303240.0 -102000.0 -0.59 -0.2909 -0.4683 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P08 compound treatment 391550.0 -25900.0 -0.15 203790.0 -202000.0 -1.17 -0.9309 -0.7891 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P09 compound treatment 365960.0 -51500.0 -0.29 278370.0 -127000.0 -0.74 -0.727 -0.9167 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P10 compound treatment 221330.0 -196000.0 -1.1 208280.0 -197000.0 -1.14 -1.5901 -0.9998 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P11 mock treatment 458720.0 41200.0 0.23 331690.0 -73900.0 -0.43 -0.1391 -0.2851 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P12 mock treatment 463870.0 46400.0 0.26 278030.0 -128000.0 -0.74 -0.3386 -0.4315 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P13 compound treatment 254080.0 -163000.0 -0.92 320480.0 -85200.0 -0.49 -0.9996 -0.9575 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P14 compound treatment 328100.0 -89400.0 -0.5 410280.0 4640.0 0.03 -0.3367 -0.6683 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P15 compound treatment 351730.0 -65700.0 -0.37 293080.0 -113000.0 -0.65 -0.7233 -0.9639 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P16 compound treatment 319040.0 -98400.0 -0.55 332640.0 -73000.0 -0.42 -0.6912 -0.9912 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P17 compound treatment 297280.0 -120000.0 -0.68 305440.0 -100000.0 -0.58 -0.8893 -0.9971 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P18 compound treatment 314810.0 -103000.0 -0.58 322990.0 -82600.0 -0.48 -0.7476 -0.9957 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P19 compound treatment 369920.0 -47600.0 -0.27 380600.0 -25000.0 -0.15 -0.292 -0.9587 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P20 compound treatment 310170.0 -107000.0 -0.6 261710.0 -144000.0 -0.83 -1.0174 -0.9874 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P21 compound treatment 329780.0 -87700.0 -0.49 303320.0 -102000.0 -0.59 -0.7687 -0.9958 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P22 compound treatment 368680.0 -48800.0 -0.27 377720.0 -27900.0 -0.16 -0.3087 -0.9682 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P23 compound treatment 329070.0 -88400.0 -0.5 361190.0 -44400.0 -0.26 -0.5342 -0.9531 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2098 P24 compound treatment 332800.0 -84700.0 -0.48 461490.0 55900.0 0.32 -0.108 -0.1874 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A01 compound treatment 500830.0 48800.0 0.27 465680.0 1870.0 0.01 0.2021 0.7345 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A02 compound treatment 493810.0 41800.0 0.24 482840.0 19000.0 0.11 0.2445 0.9404 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A03 compound treatment 545330.0 93300.0 0.53 507700.0 43900.0 0.25 0.5515 0.9447 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A04 compound treatment 180820.0 -271000.0 -1.53 485660.0 21900.0 0.13 -0.9899 -0.6462 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A05 compound treatment 226400.0 -226000.0 -1.27 384670.0 -79100.0 -0.46 -1.2226 -0.9053 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A06 compound treatment 322420.0 -130000.0 -0.73 473480.0 9670.0 0.06 -0.4761 -0.6508 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A07 compound treatment 265820.0 -186000.0 -1.05 352640.0 -111000.0 -0.64 -1.197 -0.9728 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A08 compound treatment 211040.0 -241000.0 -1.36 554170.0 90400.0 0.52 -0.5886 -0.4048 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A09 compound treatment 332010.0 -120000.0 -0.68 356840.0 -107000.0 -0.62 -0.9163 -0.9991 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A10 compound treatment 468180.0 16200.0 0.09 439760.0 -24000.0 -0.14 -0.0342 -0.2053 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A11 compound treatment 364050.0 -87900.0 -0.5 377510.0 -86300.0 -0.5 -0.704 -1.0 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A12 compound treatment 433180.0 -18800.0 -0.11 294720.0 -169000.0 -0.98 -0.7683 -0.779 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A13 mock treatment 288530.0 -163000.0 -0.92 286240.0 -178000.0 -1.03 -1.3789 -0.9984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A14 mock treatment 325970.0 -126000.0 -0.71 449350.0 -14500.0 -0.08 -0.561 -0.7852 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A15 compound treatment 325610.0 -126000.0 -0.71 420890.0 -42900.0 -0.25 -0.6791 -0.9009 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A16 compound treatment 338020.0 -114000.0 -0.64 406180.0 -57600.0 -0.33 -0.69 -0.9538 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A17 compound treatment 351630.0 -100000.0 -0.57 402690.0 -61100.0 -0.35 -0.6502 -0.9748 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A18 compound treatment 496390.0 44400.0 0.25 379260.0 -84500.0 -0.49 -0.17 -0.3089 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A19 compound treatment 350400.0 -102000.0 -0.57 297600.0 -166000.0 -0.96 -1.086 -0.9689 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A20 compound treatment 374590.0 -77400.0 -0.44 356570.0 -107000.0 -0.62 -0.7479 -0.9849 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A21 compound treatment 465320.0 13300.0 0.07 298790.0 -165000.0 -0.96 -0.6237 -0.6497 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A22 compound treatment 360330.0 -91700.0 -0.52 272370.0 -191000.0 -1.11 -1.1499 -0.9393 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A23 compound treatment 329410.0 -123000.0 -0.69 244160.0 -220000.0 -1.27 -1.3887 -0.9586 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 A24 compound treatment 231410.0 -221000.0 -1.24 464400.0 594.0 0.0 -0.8757 -0.7051 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B01 compound treatment 341600.0 -110000.0 -0.62 321020.0 -143000.0 -0.83 -1.025 -0.99 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B02 compound treatment 415840.0 -36200.0 -0.2 330930.0 -133000.0 -0.77 -0.6888 -0.8642 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B03 compound treatment 560070.0 108000.0 0.61 376350.0 -87500.0 -0.51 0.0716 0.0903 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B04 compound treatment 314280.0 -138000.0 -0.78 512960.0 49200.0 0.29 -0.3466 -0.4196 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B05 compound treatment 512880.0 60900.0 0.34 455040.0 -8770.0 -0.05 0.2064 0.5957 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B06 compound treatment 447220.0 -4780.0 -0.03 533130.0 69300.0 0.4 0.2653 0.6583 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B07 compound treatment 533630.0 81600.0 0.46 524250.0 60400.0 0.35 0.5728 0.9911 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B08 compound treatment 462880.0 10900.0 0.06 378080.0 -85700.0 -0.5 -0.3082 -0.6153 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B09 compound treatment 381000.0 -71000.0 -0.4 433510.0 -30300.0 -0.18 -0.4069 -0.9319 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B10 compound treatment 324270.0 -128000.0 -0.72 498200.0 34400.0 0.2 -0.3674 -0.4924 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B11 compound treatment 554000.0 102000.0 0.57 442520.0 -21300.0 -0.12 0.3187 0.5427 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B12 compound treatment 444160.0 -7840.0 -0.04 594740.0 131000.0 0.76 0.5057 0.6649 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B13 mock treatment 548640.0 96600.0 0.54 384260.0 -79500.0 -0.46 0.0585 0.082 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B14 mock treatment 452980.0 982.0 0.01 396930.0 -66900.0 -0.39 -0.2703 -0.697 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B15 compound treatment 328430.0 -124000.0 -0.7 346200.0 -118000.0 -0.68 -0.9742 -1.0 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B16 compound treatment 409370.0 -42600.0 -0.24 481730.0 17900.0 0.1 -0.0962 -0.3678 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B17 compound treatment 397650.0 -54300.0 -0.31 418770.0 -45000.0 -0.26 -0.401 -0.9969 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B18 compound treatment 353160.0 -98800.0 -0.56 372200.0 -91600.0 -0.53 -0.7691 -0.9997 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B19 compound treatment 352600.0 -99400.0 -0.56 380730.0 -83100.0 -0.48 -0.7363 -0.9972 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B20 compound treatment 396590.0 -55400.0 -0.31 441140.0 -22700.0 -0.13 -0.3135 -0.9262 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B21 compound treatment 412540.0 -39500.0 -0.22 444270.0 -19500.0 -0.11 -0.2372 -0.9512 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B22 compound treatment 466040.0 14000.0 0.08 498140.0 34300.0 0.2 0.1967 0.9181 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B23 compound treatment 505220.0 53200.0 0.3 395120.0 -68700.0 -0.4 -0.0698 -0.1401 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 B24 compound treatment 302600.0 -149000.0 -0.84 521960.0 58200.0 0.34 -0.3562 -0.3931 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C01 compound treatment 272320.0 -180000.0 -1.01 514110.0 50300.0 0.29 -0.509 -0.4835 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C02 compound treatment 360800.0 -91200.0 -0.51 427240.0 -36600.0 -0.21 -0.513 -0.9235 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C03 compound treatment 513700.0 61700.0 0.35 380650.0 -83200.0 -0.48 -0.0954 -0.1605 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C04 compound treatment 356970.0 -95000.0 -0.53 354720.0 -109000.0 -0.63 -0.8256 -0.9965 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C05 compound treatment 493330.0 41300.0 0.23 219040.0 -245000.0 -1.42 -0.8392 -0.5834 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C06 compound treatment 290570.0 -161000.0 -0.91 280450.0 -183000.0 -1.06 -1.3945 -0.9969 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C07 compound treatment 280050.0 -172000.0 -0.97 472640.0 8830.0 0.05 -0.6482 -0.6687 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C08 compound treatment 415710.0 -36300.0 -0.2 212430.0 -251000.0 -1.46 -1.1753 -0.7984 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C09 compound treatment 432370.0 -19600.0 -0.11 445160.0 -18600.0 -0.11 -0.1546 -0.9999 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C10 compound treatment 484570.0 32600.0 0.18 395520.0 -68300.0 -0.4 -0.1504 -0.3446 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C11 mock treatment 332700.0 -119000.0 -0.67 454210.0 -9600.0 -0.06 -0.5142 -0.7631 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C12 mock treatment 546430.0 94400.0 0.53 518170.0 54400.0 0.32 0.5988 0.9689 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C13 compound treatment 384480.0 -67500.0 -0.38 512480.0 48700.0 0.28 -0.0692 -0.1461 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C14 compound treatment 484000.0 32000.0 0.18 325070.0 -139000.0 -0.8 -0.4415 -0.5355 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C15 mock treatment 331110.0 -121000.0 -0.68 435590.0 -28200.0 -0.16 -0.5969 -0.8528 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C16 mock treatment 458400.0 6400.0 0.04 390050.0 -73800.0 -0.43 -0.277 -0.6452 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C17 compound treatment 463550.0 11600.0 0.07 453550.0 -10300.0 -0.06 0.0039 0.0446 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C18 compound treatment 319540.0 -132000.0 -0.75 295430.0 -168000.0 -0.98 -1.2177 -0.9911 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C19 compound treatment 296070.0 -156000.0 -0.88 437660.0 -26100.0 -0.15 -0.7279 -0.8171 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C20 compound treatment 251480.0 -201000.0 -1.13 388010.0 -75800.0 -0.44 -1.109 -0.9155 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C21 compound treatment 310150.0 -142000.0 -0.8 440990.0 -22800.0 -0.13 -0.6582 -0.8132 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C22 compound treatment 242560.0 -209000.0 -1.18 423040.0 -40800.0 -0.24 -1.0009 -0.8323 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C23 compound treatment 272410.0 -180000.0 -1.01 371150.0 -92700.0 -0.54 -1.0948 -0.9563 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 C24 compound treatment 273280.0 -179000.0 -1.01 395580.0 -68200.0 -0.4 -0.9912 -0.9168 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D01 compound treatment 413450.0 -38500.0 -0.22 284720.0 -179000.0 -1.04 -0.8878 -0.8368 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D02 compound treatment 328000.0 -124000.0 -0.7 342310.0 -121000.0 -0.7 -0.9918 -1.0 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D03 compound treatment 312480.0 -140000.0 -0.79 352500.0 -111000.0 -0.65 -1.0118 -0.9953 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D04 compound treatment 354560.0 -97400.0 -0.55 363930.0 -99900.0 -0.58 -0.7974 -0.9996 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D05 compound treatment 461620.0 9620.0 0.05 486630.0 22800.0 0.13 0.1319 0.9222 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D06 compound treatment 576160.0 124000.0 0.7 500110.0 36300.0 0.21 0.6431 0.881 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D07 compound treatment 358560.0 -93400.0 -0.53 379960.0 -83800.0 -0.49 -0.7158 -0.9992 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D08 compound treatment 552040.0 100000.0 0.56 547070.0 83300.0 0.48 0.7397 0.9971 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D09 compound treatment 361040.0 -91000.0 -0.51 534240.0 70400.0 0.41 -0.0732 -0.1118 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D10 compound treatment 552000.0 100000.0 0.56 516820.0 53000.0 0.31 0.6155 0.9595 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D11 mock treatment 558880.0 107000.0 0.6 543840.0 80000.0 0.46 0.7537 0.9918 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D12 mock treatment 520180.0 68200.0 0.38 559370.0 95600.0 0.55 0.6633 0.9839 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D13 compound treatment 424420.0 -27600.0 -0.16 364760.0 -99000.0 -0.57 -0.5159 -0.8671 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D14 compound treatment 314100.0 -138000.0 -0.78 374920.0 -88900.0 -0.52 -0.9134 -0.9802 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D15 mock treatment 563050.0 111000.0 0.63 551370.0 87600.0 0.51 0.8011 0.9947 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D16 mock treatment 435860.0 -16100.0 -0.09 563570.0 99800.0 0.58 0.3449 0.5889 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D17 compound treatment 412070.0 -39900.0 -0.22 463600.0 -206.0 0.0 -0.1598 -0.7108 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D18 compound treatment 345190.0 -107000.0 -0.6 311080.0 -153000.0 -0.89 -1.0515 -0.9822 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D19 compound treatment 410840.0 -41200.0 -0.23 364800.0 -99000.0 -0.57 -0.5698 -0.9203 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D20 compound treatment 471380.0 19400.0 0.11 397670.0 -66100.0 -0.38 -0.1941 -0.4866 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D21 compound treatment 288970.0 -163000.0 -0.92 387440.0 -76400.0 -0.44 -0.9621 -0.9441 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D22 compound treatment 205950.0 -246000.0 -1.39 303850.0 -160000.0 -0.93 -1.6354 -0.981 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D23 compound treatment 345940.0 -106000.0 -0.6 419720.0 -44100.0 -0.26 -0.603 -0.9284 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 D24 compound treatment 405830.0 -46200.0 -0.26 353870.0 -110000.0 -0.64 -0.6346 -0.9217 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E01 mock treatment 477550.0 25600.0 0.14 178120.0 -286000.0 -1.66 -1.0698 -0.6433 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E02 mock treatment 570050.0 118000.0 0.66 358950.0 -105000.0 -0.61 0.0399 0.0443 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E03 compound treatment 426370.0 -25600.0 -0.14 261950.0 -202000.0 -1.17 -0.9298 -0.7883 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E04 compound treatment 448210.0 -3790.0 -0.02 481020.0 17200.0 0.1 0.0555 0.5438 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E05 compound treatment 525320.0 73300.0 0.41 367430.0 -96400.0 -0.56 -0.1033 -0.1487 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E06 compound treatment 438780.0 -13200.0 -0.07 561620.0 97800.0 0.57 0.3485 0.6091 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E07 compound treatment 362690.0 -89300.0 -0.5 493890.0 30100.0 0.17 -0.2321 -0.4362 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E08 compound treatment 419900.0 -32100.0 -0.18 411850.0 -52000.0 -0.3 -0.3408 -0.9701 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E09 mock treatment 567220.0 115000.0 0.65 577550.0 114000.0 0.66 0.9251 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E10 mock treatment 371860.0 -80100.0 -0.45 436320.0 -27500.0 -0.16 -0.4317 -0.9023 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E11 compound treatment 397920.0 -54100.0 -0.3 438460.0 -25300.0 -0.15 -0.3192 -0.9442 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E12 compound treatment 409940.0 -42100.0 -0.24 337320.0 -126000.0 -0.73 -0.6861 -0.8901 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E13 compound treatment 383720.0 -68300.0 -0.38 520530.0 56700.0 0.33 -0.0392 -0.0774 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E14 compound treatment 382500.0 -69500.0 -0.39 417720.0 -46100.0 -0.27 -0.4656 -0.9827 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E15 compound treatment 490090.0 38100.0 0.21 503400.0 39600.0 0.23 0.314 0.9994 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E16 compound treatment 558780.0 107000.0 0.6 532180.0 68400.0 0.4 0.7055 0.9796 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E17 mock treatment 401760.0 -50200.0 -0.28 515790.0 52000.0 0.3 0.0132 0.0319 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E18 mock treatment 442400.0 -9600.0 -0.05 481000.0 17200.0 0.1 0.0323 0.2848 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E19 compound treatment 257250.0 -195000.0 -1.1 372000.0 -91800.0 -0.53 -1.1517 -0.945 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E20 compound treatment 425540.0 -26500.0 -0.15 518170.0 54400.0 0.32 0.1176 0.3373 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E21 compound treatment 463970.0 12000.0 0.07 342100.0 -122000.0 -0.71 -0.4514 -0.6367 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E22 compound treatment 325480.0 -127000.0 -0.71 386590.0 -77200.0 -0.45 -0.8203 -0.975 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E23 compound treatment 431060.0 -20900.0 -0.12 365930.0 -97900.0 -0.57 -0.4847 -0.8361 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 E24 compound treatment 508320.0 56300.0 0.32 410660.0 -53100.0 -0.31 0.0063 0.0142 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F01 mock treatment 547270.0 95300.0 0.54 485760.0 22000.0 0.13 0.4693 0.8513 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F02 mock treatment 178910.0 -273000.0 -1.54 298720.0 -165000.0 -0.96 -1.7641 -0.974 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F03 compound treatment 303760.0 -148000.0 -0.83 354240.0 -110000.0 -0.64 -1.0394 -0.991 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F04 compound treatment 307370.0 -145000.0 -0.81 476700.0 12900.0 0.07 -0.5228 -0.6395 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F05 compound treatment 612840.0 161000.0 0.91 454720.0 -9090.0 -0.05 0.603 0.6648 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F06 compound treatment 337280.0 -115000.0 -0.65 499910.0 36100.0 0.21 -0.3086 -0.4546 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F07 compound treatment 586720.0 135000.0 0.76 362410.0 -101000.0 -0.59 0.1205 0.1255 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F08 compound treatment 261660.0 -190000.0 -1.07 479860.0 16100.0 0.09 -0.6918 -0.6432 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F09 mock treatment 458790.0 6790.0 0.04 475080.0 11300.0 0.07 0.0733 0.9673 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F10 mock treatment 529240.0 77200.0 0.43 273700.0 -190000.0 -1.1 -0.4721 -0.3984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F11 compound treatment 526090.0 74100.0 0.42 389320.0 -74500.0 -0.43 -0.0105 -0.0175 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F12 compound treatment 415120.0 -36900.0 -0.21 337940.0 -126000.0 -0.73 -0.663 -0.8736 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F13 compound treatment 419720.0 -32300.0 -0.18 313290.0 -151000.0 -0.87 -0.7457 -0.8364 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F14 compound treatment 553380.0 101000.0 0.57 498160.0 34400.0 0.2 0.5444 0.9006 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F15 compound treatment 391390.0 -60600.0 -0.34 607420.0 144000.0 0.83 0.3477 0.3863 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F16 compound treatment 388020.0 -64000.0 -0.36 496850.0 33000.0 0.19 -0.1192 -0.2921 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F17 mock treatment 463320.0 11300.0 0.06 490720.0 26900.0 0.16 0.1554 0.9219 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F18 mock treatment 424210.0 -27800.0 -0.16 415530.0 -48300.0 -0.28 -0.3086 -0.9622 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F19 compound treatment 482440.0 30400.0 0.17 510130.0 46300.0 0.27 0.3111 0.9764 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F20 compound treatment 459070.0 7070.0 0.04 421630.0 -42200.0 -0.24 -0.1448 -0.5843 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F21 compound treatment 406990.0 -45000.0 -0.25 406400.0 -57400.0 -0.33 -0.4146 -0.9909 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F22 compound treatment 346850.0 -105000.0 -0.59 302030.0 -162000.0 -0.94 -1.082 -0.9753 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F23 compound treatment 436270.0 -15700.0 -0.09 411950.0 -51900.0 -0.3 -0.2753 -0.878 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 F24 compound treatment 500640.0 48600.0 0.27 419160.0 -44600.0 -0.26 0.0105 0.028 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G01 compound treatment 544210.0 92200.0 0.52 308690.0 -155000.0 -0.9 -0.269 -0.259 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G02 compound treatment 549620.0 97600.0 0.55 381400.0 -82400.0 -0.48 0.0507 0.0696 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G03 mock treatment 614680.0 163000.0 0.92 316490.0 -147000.0 -0.85 0.0435 0.0347 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G04 mock treatment 360160.0 -91800.0 -0.52 412640.0 -51200.0 -0.3 -0.5754 -0.9653 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G05 compound treatment 313330.0 -139000.0 -0.78 424190.0 -39600.0 -0.23 -0.7144 -0.878 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G06 compound treatment 523520.0 71500.0 0.4 579080.0 115000.0 0.67 0.7574 0.9705 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G07 compound treatment 525920.0 73900.0 0.42 393920.0 -69900.0 -0.41 0.0077 0.0132 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G08 compound treatment 478530.0 26500.0 0.15 554100.0 90300.0 0.52 0.4759 0.8739 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G09 compound treatment 473030.0 21000.0 0.12 511770.0 48000.0 0.28 0.2804 0.9276 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G10 compound treatment 378120.0 -73900.0 -0.42 463000.0 -806.0 0.0 -0.2974 -0.715 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G11 compound treatment 476000.0 24000.0 0.14 568480.0 105000.0 0.61 0.5248 0.8438 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G12 compound treatment 555360.0 103000.0 0.58 536530.0 72700.0 0.42 0.7097 0.9875 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G13 compound treatment 578830.0 127000.0 0.71 516800.0 53000.0 0.31 0.7222 0.9291 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G14 compound treatment 328530.0 -123000.0 -0.7 428090.0 -35700.0 -0.21 -0.6379 -0.8796 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G15 compound treatment 349280.0 -103000.0 -0.58 284890.0 -179000.0 -1.04 -1.1426 -0.9619 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G16 compound treatment 528450.0 76500.0 0.43 541790.0 78000.0 0.45 0.6241 0.9997 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G17 compound treatment 415940.0 -36100.0 -0.2 498910.0 35100.0 0.2 4.0E-4 0.0015 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G18 compound treatment 379600.0 -72400.0 -0.41 539320.0 75500.0 0.44 0.0215 0.0359 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G19 mock treatment 361120.0 -90900.0 -0.51 511070.0 47300.0 0.27 -0.1679 -0.2893 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G20 mock treatment 404610.0 -47400.0 -0.27 524690.0 60900.0 0.35 0.061 0.1379 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G21 compound treatment 438030.0 -14000.0 -0.08 485160.0 21400.0 0.12 0.032 0.2179 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G22 compound treatment 472530.0 20500.0 0.12 385970.0 -77800.0 -0.45 -0.2375 -0.5096 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G23 compound treatment 409280.0 -42700.0 -0.24 423930.0 -39900.0 -0.23 -0.3336 -0.9998 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 G24 compound treatment 353690.0 -98300.0 -0.55 380600.0 -83200.0 -0.48 -0.7325 -0.9977 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H01 compound treatment 352530.0 -99500.0 -0.56 175320.0 -288000.0 -1.67 -1.579 -0.895 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H02 compound treatment 318990.0 -133000.0 -0.75 236710.0 -227000.0 -1.32 -1.4607 -0.9642 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H03 mock treatment 522080.0 70100.0 0.39 217160.0 -247000.0 -1.43 -0.7325 -0.4936 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H04 mock treatment 476320.0 24300.0 0.14 399450.0 -64400.0 -0.37 -0.1671 -0.4203 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H05 compound treatment 259320.0 -193000.0 -1.08 308700.0 -155000.0 -0.9 -1.403 -0.9957 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H06 compound treatment 219200.0 -233000.0 -1.31 272090.0 -192000.0 -1.11 -1.7129 -0.9967 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H07 compound treatment 322490.0 -130000.0 -0.73 441600.0 -22200.0 -0.13 -0.6066 -0.8193 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H08 compound treatment 574300.0 122000.0 0.69 565950.0 102000.0 0.59 0.9057 0.9972 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H09 compound treatment 429310.0 -22700.0 -0.13 436070.0 -27700.0 -0.16 -0.2041 -0.9935 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H10 compound treatment 220830.0 -231000.0 -1.3 542980.0 79200.0 0.46 -0.5955 -0.4315 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H11 compound treatment 394940.0 -57100.0 -0.32 195390.0 -268000.0 -1.56 -1.3279 -0.8354 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H12 compound treatment 361080.0 -90900.0 -0.51 320160.0 -144000.0 -0.83 -0.951 -0.9726 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H13 compound treatment 470140.0 18100.0 0.1 335000.0 -129000.0 -0.75 -0.456 -0.6048 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H14 compound treatment 435680.0 -16300.0 -0.09 456180.0 -7630.0 -0.04 -0.0962 -0.9438 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H15 compound treatment 574210.0 122000.0 0.69 534010.0 70200.0 0.41 0.7744 0.9687 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H16 compound treatment 494600.0 42600.0 0.24 528640.0 64800.0 0.38 0.4355 0.9764 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H17 compound treatment 426520.0 -25500.0 -0.14 401390.0 -62400.0 -0.36 -0.3574 -0.9179 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H18 compound treatment 536570.0 84600.0 0.48 526150.0 62300.0 0.36 0.5923 0.9908 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H19 mock treatment 396480.0 -55500.0 -0.31 526960.0 63200.0 0.37 0.038 0.0789 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H20 mock treatment 493600.0 41600.0 0.23 556480.0 92700.0 0.54 0.5456 0.9307 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H21 compound treatment 454170.0 2170.0 0.01 492560.0 28800.0 0.17 0.1266 0.7569 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H22 compound treatment 428730.0 -23300.0 -0.13 455840.0 -7970.0 -0.05 -0.1253 -0.902 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H23 compound treatment 427790.0 -24200.0 -0.14 383680.0 -80100.0 -0.46 -0.4249 -0.8775 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 H24 compound treatment 261220.0 -191000.0 -1.07 345560.0 -118000.0 -0.69 -1.2443 -0.9765 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I01 compound treatment 572430.0 120000.0 0.68 520070.0 56300.0 0.33 0.7101 0.9438 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I02 compound treatment 218740.0 -233000.0 -1.31 503480.0 39700.0 0.23 -0.7658 -0.5745 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I03 compound treatment 575100.0 123000.0 0.69 345370.0 -118000.0 -0.69 0.0043 0.0045 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I04 compound treatment 616590.0 165000.0 0.93 565340.0 102000.0 0.59 1.0716 0.9761 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I05 mock treatment 544760.0 92800.0 0.52 516840.0 53000.0 0.31 0.5867 0.9681 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I06 mock treatment 416530.0 -35500.0 -0.2 586160.0 122000.0 0.71 0.3606 0.4891 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I07 compound treatment 383700.0 -68300.0 -0.38 419740.0 -44100.0 -0.26 -0.4526 -0.9803 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I08 compound treatment 430400.0 -21600.0 -0.12 236330.0 -227000.0 -1.32 -1.0188 -0.769 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I09 compound treatment 524220.0 72200.0 0.41 542650.0 78800.0 0.46 0.6108 0.9983 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I10 compound treatment 548800.0 96800.0 0.54 311040.0 -153000.0 -0.89 -0.2411 -0.2318 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I11 compound treatment 559870.0 108000.0 0.61 443040.0 -20800.0 -0.12 0.3442 0.5561 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I12 compound treatment 479170.0 27200.0 0.15 283950.0 -180000.0 -1.04 -0.6294 -0.597 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I13 compound treatment 621220.0 169000.0 0.95 537190.0 73400.0 0.43 0.9746 0.934 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I14 compound treatment 595360.0 143000.0 0.81 532650.0 68800.0 0.4 0.853 0.9473 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I15 compound treatment 566970.0 115000.0 0.65 569170.0 105000.0 0.61 0.8897 0.9996 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I16 compound treatment 518880.0 66900.0 0.38 517920.0 54100.0 0.31 0.4881 0.9959 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I17 compound treatment 411840.0 -40200.0 -0.23 456640.0 -7170.0 -0.04 -0.1892 -0.8233 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I18 compound treatment 425840.0 -26200.0 -0.15 597570.0 134000.0 0.78 0.4444 0.5628 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I19 compound treatment 533230.0 81200.0 0.46 395280.0 -68500.0 -0.4 0.0423 0.0699 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I20 compound treatment 447360.0 -4640.0 -0.03 450560.0 -13200.0 -0.08 -0.0728 -0.8971 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I21 mock treatment 335940.0 -116000.0 -0.65 440060.0 -23700.0 -0.14 -0.5594 -0.8377 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I22 mock treatment 317170.0 -135000.0 -0.76 458590.0 -5220.0 -0.03 -0.5581 -0.7347 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I23 compound treatment 347850.0 -104000.0 -0.59 332240.0 -132000.0 -0.76 -0.9541 -0.9915 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 I24 compound treatment 353710.0 -98300.0 -0.55 483110.0 19300.0 0.11 -0.3121 -0.5528 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J01 compound treatment 153810.0 -298000.0 -1.68 511650.0 47800.0 0.28 -0.9908 -0.5823 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J02 compound treatment 524190.0 72200.0 0.41 347560.0 -116000.0 -0.67 -0.1893 -0.2405 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J03 compound treatment 220670.0 -231000.0 -1.3 315560.0 -148000.0 -0.86 -1.5288 -0.9797 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J04 compound treatment 513870.0 61900.0 0.35 274670.0 -189000.0 -1.1 -0.5293 -0.4599 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J05 mock treatment 501190.0 49200.0 0.28 405340.0 -58500.0 -0.34 -0.0439 -0.1004 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J06 mock treatment 298240.0 -154000.0 -0.87 415170.0 -48600.0 -0.28 -0.8115 -0.8914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J07 compound treatment 371610.0 -80400.0 -0.45 466170.0 2360.0 0.01 -0.3103 -0.6854 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J08 compound treatment 406460.0 -45500.0 -0.26 436050.0 -27800.0 -0.16 -0.2951 -0.9749 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J09 compound treatment 434630.0 -17400.0 -0.1 539570.0 75800.0 0.44 0.2416 0.5366 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J10 compound treatment 440010.0 -12000.0 -0.07 329730.0 -134000.0 -0.78 -0.5975 -0.7656 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J11 compound treatment 236290.0 -216000.0 -1.21 491600.0 27800.0 0.16 -0.7447 -0.6079 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J12 compound treatment 459930.0 7930.0 0.04 605380.0 142000.0 0.82 0.6121 0.7445 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J13 compound treatment 511440.0 59400.0 0.33 564980.0 101000.0 0.59 0.6515 0.9645 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J14 compound treatment 484640.0 32600.0 0.18 504960.0 41200.0 0.24 0.2987 0.9917 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J15 compound treatment 503100.0 51100.0 0.29 428160.0 -35600.0 -0.21 0.0572 0.1616 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J16 compound treatment 492010.0 40000.0 0.23 438560.0 -25200.0 -0.15 0.0557 0.2075 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J17 compound treatment 527580.0 75600.0 0.43 506100.0 42300.0 0.25 0.4743 0.9658 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J18 compound treatment 529230.0 77200.0 0.43 422730.0 -41100.0 -0.24 0.139 0.2804 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J19 compound treatment 477470.0 25500.0 0.14 381880.0 -81900.0 -0.48 -0.2346 -0.4726 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J20 compound treatment 441290.0 -10700.0 -0.06 472580.0 8770.0 0.05 -0.0066 -0.0842 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J21 mock treatment 416760.0 -35200.0 -0.2 424970.0 -38800.0 -0.23 -0.2995 -0.998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J22 mock treatment 376050.0 -75900.0 -0.43 329280.0 -135000.0 -0.78 -0.854 -0.9599 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J23 compound treatment 438930.0 -13100.0 -0.07 522730.0 58900.0 0.34 0.1896 0.5425 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 J24 compound treatment 293840.0 -158000.0 -0.89 290630.0 -173000.0 -1.0 -1.3397 -0.9982 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K01 compound treatment 362410.0 -89600.0 -0.5 469450.0 5640.0 0.03 -0.3335 -0.6598 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K02 compound treatment 351150.0 -101000.0 -0.57 406260.0 -57500.0 -0.33 -0.6374 -0.9679 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K03 compound treatment 549520.0 97500.0 0.55 405970.0 -57800.0 -0.34 0.151 0.2348 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K04 compound treatment 512410.0 60400.0 0.34 525610.0 61800.0 0.36 0.4939 0.9997 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K05 compound treatment 255730.0 -196000.0 -1.1 219300.0 -245000.0 -1.42 -1.7839 -0.9924 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K06 compound treatment 225790.0 -226000.0 -1.27 227840.0 -236000.0 -1.37 -1.8681 -0.9994 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K07 mock treatment 513340.0 61300.0 0.35 221730.0 -242000.0 -1.4 -0.7485 -0.5177 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K08 mock treatment 574250.0 122000.0 0.69 489300.0 25500.0 0.15 0.5912 0.8399 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K09 compound treatment 293990.0 -158000.0 -0.89 409460.0 -54300.0 -0.32 -0.8518 -0.9027 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K10 compound treatment 266320.0 -186000.0 -1.05 181480.0 -282000.0 -1.64 -1.8969 -0.9765 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K11 compound treatment 558950.0 107000.0 0.6 453180.0 -10600.0 -0.06 0.3822 0.6314 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K12 compound treatment 526530.0 74500.0 0.42 280580.0 -183000.0 -1.06 -0.4547 -0.398 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K13 compound treatment 520530.0 68500.0 0.39 553130.0 89300.0 0.52 0.6391 0.9895 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K14 compound treatment 541020.0 89000.0 0.5 480000.0 16200.0 0.09 0.4208 0.8253 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K15 mock treatment 529790.0 77800.0 0.44 483270.0 19500.0 0.11 0.3895 0.8612 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K16 mock treatment 605000.0 153000.0 0.86 604220.0 140000.0 0.81 1.1849 0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K17 compound treatment 585120.0 133000.0 0.75 542080.0 78300.0 0.45 0.8509 0.9712 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K18 compound treatment 631750.0 180000.0 1.01 585640.0 122000.0 0.71 1.2152 0.9846 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K19 compound treatment 455880.0 3880.0 0.02 520880.0 57100.0 0.33 0.2495 0.7522 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K20 compound treatment 344240.0 -108000.0 -0.61 460840.0 -2970.0 -0.02 -0.4411 -0.7269 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K21 compound treatment 444640.0 -7360.0 -0.04 476000.0 12200.0 0.07 0.0207 0.2528 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K22 compound treatment 395430.0 -56600.0 -0.32 401060.0 -62700.0 -0.36 -0.4825 -0.9978 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K23 mock treatment 504750.0 52800.0 0.3 413350.0 -50500.0 -0.29 0.0031 0.0074 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 K24 mock treatment 441450.0 -10500.0 -0.06 515570.0 51800.0 0.3 0.1703 0.5565 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L01 compound treatment 269200.0 -183000.0 -1.03 348340.0 -115000.0 -0.67 -1.2012 -0.9783 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L02 compound treatment 403440.0 -48600.0 -0.27 488430.0 24600.0 0.14 -0.0923 -0.2993 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L03 compound treatment 277960.0 -174000.0 -0.98 350460.0 -113000.0 -0.66 -1.1576 -0.9812 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L04 compound treatment 379480.0 -72500.0 -0.41 425790.0 -38000.0 -0.22 -0.4446 -0.9582 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L05 compound treatment 298410.0 -154000.0 -0.86 358590.0 -105000.0 -0.61 -1.0429 -0.9854 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L06 compound treatment 190650.0 -261000.0 -1.47 413830.0 -50000.0 -0.29 -1.2453 -0.8304 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L07 mock treatment 330740.0 -121000.0 -0.68 374830.0 -89000.0 -0.52 -0.8476 -0.9905 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L08 mock treatment 300290.0 -152000.0 -0.85 570200.0 106000.0 0.62 -0.1676 -0.1591 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L09 compound treatment 298840.0 -153000.0 -0.86 600690.0 137000.0 0.79 -0.0483 -0.0412 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L10 compound treatment 416280.0 -35700.0 -0.2 596560.0 133000.0 0.77 0.4022 0.5055 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L11 compound treatment 548110.0 96100.0 0.54 530810.0 67000.0 0.39 0.6574 0.9868 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L12 compound treatment 342240.0 -110000.0 -0.62 436670.0 -27100.0 -0.16 -0.5482 -0.8598 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L13 compound treatment 337000.0 -115000.0 -0.65 455750.0 -8060.0 -0.05 -0.4908 -0.7562 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L14 compound treatment 528080.0 76100.0 0.43 525320.0 61500.0 0.36 0.5551 0.9959 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L15 mock treatment 507200.0 55200.0 0.31 587360.0 124000.0 0.72 0.7264 0.9301 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L16 mock treatment 480500.0 28500.0 0.16 472030.0 8220.0 0.05 0.1472 0.8793 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L17 compound treatment 375040.0 -77000.0 -0.43 432180.0 -31600.0 -0.18 -0.436 -0.9268 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L18 compound treatment 535400.0 83400.0 0.47 526370.0 62600.0 0.36 0.5886 0.9919 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L19 compound treatment 488030.0 36000.0 0.2 458560.0 -5250.0 -0.03 0.1219 0.5944 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L20 compound treatment 463910.0 11900.0 0.07 449970.0 -13800.0 -0.08 -0.0093 -0.0891 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L21 compound treatment 333760.0 -118000.0 -0.67 483210.0 19400.0 0.11 -0.3911 -0.5793 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L22 compound treatment 424420.0 -27600.0 -0.16 506530.0 42700.0 0.25 0.0654 0.2238 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L23 mock treatment 394200.0 -57800.0 -0.33 472890.0 9080.0 0.05 -0.1928 -0.585 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 L24 mock treatment 474000.0 22000.0 0.12 497180.0 33400.0 0.19 0.2244 0.9767 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M01 compound treatment 434900.0 -17100.0 -0.1 391810.0 -72000.0 -0.42 -0.3633 -0.8479 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M02 compound treatment 488750.0 36800.0 0.21 516160.0 52400.0 0.3 0.361 0.9825 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M03 compound treatment 460840.0 8840.0 0.05 520230.0 56400.0 0.33 0.2666 0.8054 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M04 compound treatment 512060.0 60100.0 0.34 374100.0 -89700.0 -0.52 -0.1288 -0.2076 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M05 compound treatment 294640.0 -157000.0 -0.89 369280.0 -94500.0 -0.55 -1.014 -0.9734 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M06 compound treatment 161400.0 -291000.0 -1.64 390660.0 -73100.0 -0.42 -1.4567 -0.862 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M07 compound treatment 296430.0 -156000.0 -0.88 252030.0 -212000.0 -1.23 -1.4877 -0.9863 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M08 compound treatment 414750.0 -37200.0 -0.21 293790.0 -170000.0 -0.99 -0.8455 -0.8387 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M09 mock treatment 503450.0 51500.0 0.29 570470.0 107000.0 0.62 0.6422 0.9402 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M10 mock treatment 453550.0 1550.0 0.01 433670.0 -30100.0 -0.17 -0.1174 -0.6709 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M11 compound treatment 375430.0 -76600.0 -0.43 514720.0 50900.0 0.3 -0.096 -0.1837 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M12 compound treatment 386780.0 -65200.0 -0.37 473980.0 10200.0 0.06 -0.2179 -0.5859 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M13 mock treatment 606560.0 155000.0 0.87 475000.0 11200.0 0.06 0.6612 0.7578 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M14 mock treatment 445550.0 -6450.0 -0.04 513160.0 49400.0 0.29 0.1767 0.6125 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M15 compound treatment 417980.0 -34000.0 -0.19 437940.0 -25900.0 -0.15 -0.2415 -0.9927 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M16 compound treatment 366200.0 -85800.0 -0.48 460270.0 -3540.0 -0.02 -0.356 -0.7365 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M17 compound treatment 307150.0 -145000.0 -0.82 537560.0 73800.0 0.43 -0.2741 -0.2977 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M18 compound treatment 467360.0 15400.0 0.09 462880.0 -926.0 -0.01 0.0574 0.6619 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M19 compound treatment 336570.0 -115000.0 -0.65 441240.0 -22600.0 -0.13 -0.552 -0.8328 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M20 compound treatment 336040.0 -116000.0 -0.65 433810.0 -30000.0 -0.17 -0.5846 -0.8653 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M21 compound treatment 403580.0 -48400.0 -0.27 438600.0 -25200.0 -0.15 -0.2961 -0.9573 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M22 compound treatment 365810.0 -86200.0 -0.49 444420.0 -19400.0 -0.11 -0.4226 -0.8485 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M23 compound treatment 308440.0 -144000.0 -0.81 501280.0 37500.0 0.22 -0.4178 -0.4992 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 M24 compound treatment 381960.0 -70000.0 -0.39 470560.0 6750.0 0.04 -0.2511 -0.6337 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N01 compound treatment 238560.0 -213000.0 -1.2 517490.0 53700.0 0.31 -0.6295 -0.5071 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N02 compound treatment 352290.0 -99700.0 -0.56 375560.0 -88200.0 -0.51 -0.7588 -0.9989 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N03 compound treatment 594750.0 143000.0 0.8 521120.0 57300.0 0.33 0.8033 0.9237 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N04 compound treatment 428720.0 -23300.0 -0.13 392900.0 -70900.0 -0.41 -0.3834 -0.8884 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N05 compound treatment 494170.0 42200.0 0.24 286150.0 -178000.0 -1.03 -0.5607 -0.5303 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N06 compound treatment 200160.0 -252000.0 -1.42 328490.0 -135000.0 -0.78 -1.5574 -0.9611 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N07 compound treatment 384520.0 -67500.0 -0.38 465570.0 1760.0 0.01 -0.2614 -0.6878 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N08 compound treatment 509310.0 57300.0 0.32 469120.0 5310.0 0.03 0.2499 0.7711 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N09 mock treatment 560030.0 108000.0 0.61 605030.0 141000.0 0.82 1.0092 0.9893 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N10 mock treatment 392320.0 -59700.0 -0.34 549660.0 85900.0 0.5 0.1145 0.1906 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N11 compound treatment 540040.0 88000.0 0.5 465370.0 1560.0 0.01 0.3569 0.7199 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N12 compound treatment 281300.0 -171000.0 -0.96 510940.0 47100.0 0.27 -0.4862 -0.4867 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N13 mock treatment 441490.0 -10500.0 -0.06 389510.0 -74300.0 -0.43 -0.3465 -0.7967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N14 mock treatment 365820.0 -86200.0 -0.49 478020.0 14200.0 0.08 -0.2848 -0.5787 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N15 compound treatment 464680.0 12700.0 0.07 565920.0 102000.0 0.59 0.4692 0.7867 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N16 compound treatment 411480.0 -40500.0 -0.23 461760.0 -2050.0 -0.01 -0.1697 -0.7429 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N17 compound treatment 359610.0 -92400.0 -0.52 451470.0 -12300.0 -0.07 -0.4184 -0.7969 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N18 compound treatment 369820.0 -82200.0 -0.46 504910.0 41100.0 0.24 -0.1586 -0.3047 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N19 compound treatment 460500.0 8500.0 0.05 455710.0 -8100.0 -0.05 6.0E-4 0.0096 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N20 compound treatment 414990.0 -37000.0 -0.21 482430.0 18600.0 0.11 -0.0709 -0.3023 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N21 compound treatment 376510.0 -75500.0 -0.42 356930.0 -107000.0 -0.62 -0.7388 -0.983 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N22 compound treatment 464870.0 12900.0 0.07 379270.0 -84500.0 -0.49 -0.2954 -0.5961 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N23 compound treatment 403790.0 -48200.0 -0.27 343920.0 -120000.0 -0.7 -0.6835 -0.9158 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 N24 compound treatment 341130.0 -111000.0 -0.62 402430.0 -61400.0 -0.36 -0.693 -0.9645 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O01 compound treatment 484480.0 32500.0 0.18 269530.0 -194000.0 -1.13 -0.6674 -0.5847 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O02 compound treatment 538960.0 87000.0 0.49 350200.0 -114000.0 -0.66 -0.1197 -0.1458 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O03 compound treatment 289340.0 -163000.0 -0.92 538020.0 74200.0 0.43 -0.3431 -0.3391 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O04 compound treatment 384480.0 -67500.0 -0.38 379750.0 -84100.0 -0.49 -0.6135 -0.9924 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O05 compound treatment 533970.0 82000.0 0.46 400970.0 -62800.0 -0.36 0.0686 0.1167 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O06 compound treatment 341320.0 -111000.0 -0.62 488040.0 24200.0 0.14 -0.3412 -0.5342 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O07 compound treatment 462830.0 10800.0 0.06 320930.0 -143000.0 -0.83 -0.5428 -0.6533 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O08 compound treatment 509160.0 57200.0 0.32 421440.0 -42400.0 -0.25 0.0538 0.1329 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O09 compound treatment 546200.0 94200.0 0.53 492260.0 28500.0 0.17 0.4917 0.8853 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O10 compound treatment 418720.0 -33300.0 -0.19 402080.0 -61700.0 -0.36 -0.3856 -0.9544 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O11 mock treatment 482240.0 30200.0 0.17 432550.0 -31300.0 -0.18 -0.0078 -0.0313 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O12 mock treatment 417360.0 -34600.0 -0.19 529280.0 65500.0 0.38 0.1306 0.306 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O13 compound treatment 445660.0 -6340.0 -0.04 420390.0 -43400.0 -0.25 -0.2033 -0.7993 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O14 compound treatment 551520.0 99500.0 0.56 419840.0 -44000.0 -0.25 0.2159 0.3507 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O15 compound treatment 511810.0 59800.0 0.34 537050.0 73200.0 0.42 0.5385 0.9934 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O16 compound treatment 526080.0 74100.0 0.42 503880.0 40100.0 0.23 0.4592 0.9619 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O17 compound treatment 497640.0 45600.0 0.26 524320.0 60500.0 0.35 0.4298 0.9883 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O18 compound treatment 425520.0 -26500.0 -0.15 442370.0 -21400.0 -0.12 -0.1933 -0.9959 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O19 compound treatment 453160.0 1160.0 0.01 534140.0 70300.0 0.41 0.2931 0.7184 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O20 compound treatment 380120.0 -71900.0 -0.4 511910.0 48100.0 0.28 -0.0889 -0.1808 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O21 compound treatment 436540.0 -15500.0 -0.09 491520.0 27700.0 0.16 0.0521 0.2852 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O22 compound treatment 377310.0 -74700.0 -0.42 447040.0 -16800.0 -0.1 -0.3661 -0.8482 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O23 compound treatment 412160.0 -39800.0 -0.22 537240.0 73400.0 0.43 0.1426 0.2962 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 O24 compound treatment 427780.0 -24200.0 -0.14 529230.0 65400.0 0.38 0.1719 0.4263 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P01 compound treatment 405240.0 -46800.0 -0.26 402560.0 -61200.0 -0.36 -0.4373 -0.9891 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P02 compound treatment 348190.0 -104000.0 -0.58 329080.0 -135000.0 -0.78 -0.9657 -0.9898 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P03 compound treatment 207320.0 -245000.0 -1.38 171600.0 -292000.0 -1.69 -2.1723 -0.9947 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P04 compound treatment 224930.0 -227000.0 -1.28 303850.0 -160000.0 -0.93 -1.5598 -0.9876 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P05 compound treatment 239520.0 -212000.0 -1.2 233470.0 -230000.0 -1.34 -1.7904 -0.9985 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P06 compound treatment 288990.0 -163000.0 -0.92 289410.0 -174000.0 -1.01 -1.364 -0.9988 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P07 compound treatment 490270.0 38300.0 0.22 421020.0 -42800.0 -0.25 -0.0231 -0.0703 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P08 compound treatment 346880.0 -105000.0 -0.59 212430.0 -251000.0 -1.46 -1.4493 -0.9211 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P09 compound treatment 315890.0 -136000.0 -0.77 412320.0 -51500.0 -0.3 -0.7529 -0.9156 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P10 compound treatment 447520.0 -4480.0 -0.03 409020.0 -54800.0 -0.32 -0.2425 -0.7608 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P11 mock treatment 284710.0 -167000.0 -0.94 352400.0 -111000.0 -0.65 -1.1228 -0.9831 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P12 mock treatment 415200.0 -36800.0 -0.21 316930.0 -147000.0 -0.85 -0.7488 -0.8542 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P13 compound treatment 336570.0 -115000.0 -0.65 210720.0 -253000.0 -1.47 -1.4973 -0.9328 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P14 compound treatment 321440.0 -131000.0 -0.73 484340.0 20500.0 0.12 -0.4355 -0.5849 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P15 compound treatment 377920.0 -74100.0 -0.42 323490.0 -140000.0 -0.81 -0.8703 -0.9518 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P16 compound treatment 298020.0 -154000.0 -0.87 384020.0 -79800.0 -0.46 -0.9401 -0.9568 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P17 compound treatment 429920.0 -22100.0 -0.12 366880.0 -96900.0 -0.56 -0.4854 -0.8431 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P18 compound treatment 356240.0 -95800.0 -0.54 293530.0 -170000.0 -0.99 -1.0794 -0.9595 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P19 compound treatment 367040.0 -85000.0 -0.48 316420.0 -147000.0 -0.85 -0.9426 -0.9624 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P20 compound treatment 292000.0 -160000.0 -0.9 442510.0 -21300.0 -0.12 -0.7242 -0.7966 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P21 compound treatment 409090.0 -42900.0 -0.24 434520.0 -29300.0 -0.17 -0.2909 -0.9851 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P22 compound treatment 322420.0 -130000.0 -0.73 406510.0 -57300.0 -0.33 -0.7508 -0.9366 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P23 compound treatment 345600.0 -106000.0 -0.6 428010.0 -35800.0 -0.21 -0.5703 -0.8997 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2100 P24 compound treatment 256200.0 -196000.0 -1.1 452680.0 -11100.0 -0.06 -0.825 -0.7472 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A01 compound treatment 461360.0 40200.0 0.23 255240.0 -107000.0 -0.62 -0.2788 -0.4219 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A02 compound treatment 432410.0 11300.0 0.06 236570.0 -126000.0 -0.73 -0.4706 -0.643 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A03 compound treatment 411760.0 -9350.0 -0.05 201320.0 -161000.0 -0.93 -0.6974 -0.7458 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A04 compound treatment 233360.0 -188000.0 -1.06 247520.0 -115000.0 -0.67 -1.2181 -0.9752 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A05 compound treatment 224120.0 -197000.0 -1.11 269010.0 -93300.0 -0.54 -1.1667 -0.9456 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A06 compound treatment 385450.0 -35700.0 -0.2 368370.0 6070.0 0.04 -0.1171 -0.5744 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A07 compound treatment 408170.0 -12900.0 -0.07 244580.0 -118000.0 -0.68 -0.5343 -0.7781 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A08 compound treatment 349340.0 -71800.0 -0.4 425470.0 63200.0 0.37 -0.0267 -0.0489 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A09 compound treatment 416370.0 -4740.0 -0.03 377530.0 15200.0 0.09 0.0436 0.4723 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A10 compound treatment 322480.0 -98600.0 -0.56 345360.0 -16900.0 -0.1 -0.4621 -0.8195 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A11 compound treatment 408280.0 -12800.0 -0.07 406880.0 44600.0 0.26 0.1317 0.4907 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A12 compound treatment 284720.0 -136000.0 -0.77 234580.0 -128000.0 -0.74 -1.0667 -0.9998 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A13 mock treatment 406510.0 -14600.0 -0.08 213690.0 -149000.0 -0.86 -0.6676 -0.771 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A14 mock treatment 262300.0 -159000.0 -0.89 219900.0 -142000.0 -0.83 -1.2161 -0.9992 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A15 compound treatment 374080.0 -47000.0 -0.26 205670.0 -157000.0 -0.91 -0.8295 -0.8767 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A16 compound treatment 451170.0 30100.0 0.17 285080.0 -77200.0 -0.45 -0.197 -0.4115 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A17 compound treatment 437690.0 16600.0 0.09 217980.0 -144000.0 -0.84 -0.5258 -0.6244 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A18 compound treatment 409280.0 -11800.0 -0.07 293080.0 -69200.0 -0.4 -0.331 -0.8133 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A19 compound treatment 290500.0 -131000.0 -0.74 302720.0 -59600.0 -0.35 -0.7643 -0.9407 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A20 compound treatment 370490.0 -50600.0 -0.28 355460.0 -6840.0 -0.04 -0.2296 -0.7979 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A21 compound treatment 407570.0 -13500.0 -0.08 229980.0 -132000.0 -0.77 -0.5965 -0.7735 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A22 compound treatment 394010.0 -27100.0 -0.15 260290.0 -102000.0 -0.59 -0.5262 -0.8613 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A23 compound treatment 462240.0 41100.0 0.23 251840.0 -110000.0 -0.64 -0.2893 -0.4247 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 A24 compound treatment 318970.0 -102000.0 -0.58 254970.0 -107000.0 -0.62 -0.8467 -0.9992 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B01 compound treatment 412020.0 -9090.0 -0.05 242570.0 -120000.0 -0.69 -0.5272 -0.7572 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B02 compound treatment 508440.0 87300.0 0.49 434400.0 72100.0 0.42 0.6433 0.9968 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B03 compound treatment 478090.0 57000.0 0.32 480810.0 119000.0 0.69 0.7128 0.9398 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B04 compound treatment 378400.0 -42700.0 -0.24 477190.0 115000.0 0.67 0.3011 0.4251 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B05 compound treatment 216330.0 -205000.0 -1.15 361870.0 -434.0 0.0 -0.8169 -0.7087 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B06 compound treatment 398560.0 -22600.0 -0.13 392820.0 30500.0 0.18 0.0354 0.1624 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B07 compound treatment 395550.0 -25600.0 -0.14 247740.0 -115000.0 -0.66 -0.5716 -0.8408 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B08 compound treatment 458830.0 37700.0 0.21 370040.0 7740.0 0.04 0.1819 0.838 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B09 compound treatment 563620.0 143000.0 0.8 486240.0 124000.0 0.72 1.0755 0.9985 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B10 compound treatment 410400.0 -10700.0 -0.06 341360.0 -20900.0 -0.12 -0.1285 -0.9478 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B11 compound treatment 492860.0 71700.0 0.4 393960.0 31700.0 0.18 0.4154 0.9363 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B12 compound treatment 431930.0 10800.0 0.06 406140.0 43800.0 0.25 0.2228 0.8524 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B13 mock treatment 412930.0 -8180.0 -0.05 510760.0 148000.0 0.86 0.5762 0.6683 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B14 mock treatment 512800.0 91700.0 0.52 320640.0 -41700.0 -0.24 0.1941 0.3406 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B15 compound treatment 425710.0 4600.0 0.03 501600.0 139000.0 0.81 0.5895 0.7294 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B16 compound treatment 355590.0 -65500.0 -0.37 464160.0 102000.0 0.59 0.1569 0.2253 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B17 compound treatment 547250.0 126000.0 0.71 417460.0 55200.0 0.32 0.7283 0.9351 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B18 compound treatment 550630.0 130000.0 0.73 305160.0 -57100.0 -0.33 0.2812 0.3511 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B19 compound treatment 537040.0 116000.0 0.65 450250.0 87900.0 0.51 0.8221 0.9926 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B20 compound treatment 467620.0 46500.0 0.26 420240.0 57900.0 0.34 0.4227 0.9924 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B21 compound treatment 477800.0 56700.0 0.32 461410.0 99100.0 0.57 0.6321 0.9615 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B22 compound treatment 444170.0 23100.0 0.13 410610.0 48300.0 0.28 0.2899 0.9389 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B23 compound treatment 284960.0 -136000.0 -0.77 455760.0 93500.0 0.54 -0.1587 -0.1691 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 B24 compound treatment 430110.0 9000.0 0.05 378590.0 16300.0 0.09 0.1026 0.9574 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C01 compound treatment 431640.0 10500.0 0.06 420590.0 58300.0 0.34 0.2809 0.8186 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C02 compound treatment 303330.0 -118000.0 -0.66 277520.0 -84800.0 -0.49 -0.8165 -0.9892 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C03 compound treatment 447640.0 26500.0 0.15 244250.0 -118000.0 -0.68 -0.3785 -0.5402 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C04 compound treatment 245360.0 -176000.0 -0.99 394680.0 32400.0 0.19 -0.5668 -0.5629 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C05 compound treatment 351220.0 -69900.0 -0.39 356120.0 -6180.0 -0.04 -0.3036 -0.7684 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C06 compound treatment 221920.0 -199000.0 -1.12 266990.0 -95300.0 -0.55 -1.1838 -0.9469 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C07 compound treatment 322570.0 -98500.0 -0.55 287250.0 -75100.0 -0.44 -0.7 -0.9928 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C08 compound treatment 284230.0 -137000.0 -0.77 333710.0 -28600.0 -0.17 -0.6621 -0.84 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C09 compound treatment 448210.0 27100.0 0.15 372210.0 9910.0 0.06 0.1485 0.9109 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C10 compound treatment 379870.0 -41200.0 -0.23 268290.0 -94000.0 -0.55 -0.5497 -0.9276 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C11 mock treatment 424550.0 3440.0 0.02 306560.0 -55700.0 -0.32 -0.2149 -0.6636 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C12 mock treatment 485620.0 64500.0 0.36 271520.0 -90800.0 -0.53 -0.1155 -0.1806 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C13 compound treatment 219550.0 -202000.0 -1.13 320320.0 -42000.0 -0.24 -0.9745 -0.8397 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C14 compound treatment 400730.0 -20400.0 -0.11 222440.0 -140000.0 -0.81 -0.6547 -0.7992 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C15 mock treatment 396840.0 -24300.0 -0.14 320440.0 -41900.0 -0.24 -0.2683 -0.963 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C16 mock treatment 356680.0 -64400.0 -0.36 382880.0 20600.0 0.12 -0.1721 -0.4507 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C17 compound treatment 378730.0 -42400.0 -0.24 308540.0 -53800.0 -0.31 -0.3892 -0.9913 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C18 compound treatment 423480.0 2370.0 0.01 318720.0 -43600.0 -0.25 -0.1693 -0.6689 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C19 compound treatment 351040.0 -70100.0 -0.39 306130.0 -56200.0 -0.33 -0.5093 -0.9955 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C20 compound treatment 268710.0 -152000.0 -0.86 196800.0 -166000.0 -0.96 -1.2854 -0.9984 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C21 compound treatment 372550.0 -48600.0 -0.27 337710.0 -24600.0 -0.14 -0.2942 -0.954 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C22 compound treatment 385920.0 -35200.0 -0.2 378400.0 16100.0 0.09 -0.0741 -0.3383 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C23 compound treatment 408480.0 -12600.0 -0.07 281010.0 -81300.0 -0.47 -0.3836 -0.8046 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 C24 compound treatment 369280.0 -51800.0 -0.29 356750.0 -5550.0 -0.03 -0.2291 -0.7804 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D01 compound treatment 259620.0 -161000.0 -0.91 334640.0 -27700.0 -0.16 -0.7563 -0.8192 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D02 compound treatment 483360.0 62200.0 0.35 482950.0 121000.0 0.7 0.7425 0.9489 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D03 compound treatment 397880.0 -23200.0 -0.13 216800.0 -146000.0 -0.84 -0.6892 -0.8071 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D04 compound treatment 461760.0 40600.0 0.23 276970.0 -85300.0 -0.49 -0.1881 -0.345 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D05 compound treatment 469550.0 48400.0 0.27 309530.0 -52800.0 -0.31 -0.0236 -0.0576 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D06 compound treatment 548820.0 128000.0 0.72 420750.0 58400.0 0.34 0.748 0.9411 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D07 compound treatment 515470.0 94400.0 0.53 309160.0 -53100.0 -0.31 0.1577 0.2568 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D08 compound treatment 370460.0 -50700.0 -0.29 310110.0 -52200.0 -0.3 -0.4157 -0.9996 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D09 compound treatment 483200.0 62100.0 0.35 355770.0 -6530.0 -0.04 0.2204 0.6268 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D10 compound treatment 344850.0 -76300.0 -0.43 423460.0 61200.0 0.35 -0.0528 -0.0948 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D11 mock treatment 439200.0 18100.0 0.1 469730.0 107000.0 0.62 0.5125 0.8119 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D12 mock treatment 469440.0 48300.0 0.27 372180.0 9880.0 0.06 0.2329 0.8376 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D13 compound treatment 467140.0 46000.0 0.26 238080.0 -124000.0 -0.72 -0.3262 -0.4261 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D14 compound treatment 356870.0 -64200.0 -0.36 354620.0 -7680.0 -0.04 -0.2872 -0.7883 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D15 mock treatment 471600.0 50500.0 0.28 339450.0 -22900.0 -0.13 0.1073 0.342 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D16 mock treatment 391520.0 -29600.0 -0.17 409020.0 46700.0 0.27 0.0738 0.232 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D17 compound treatment 336160.0 -85000.0 -0.48 277720.0 -84600.0 -0.49 -0.685 -0.9999 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D18 compound treatment 519790.0 98700.0 0.56 439690.0 77400.0 0.45 0.7102 0.9944 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D19 compound treatment 459550.0 38400.0 0.22 272370.0 -89900.0 -0.52 -0.2158 -0.3821 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D20 compound treatment 478360.0 57200.0 0.32 380130.0 17800.0 0.1 0.301 0.8893 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D21 compound treatment 504090.0 83000.0 0.47 378920.0 16600.0 0.1 0.3985 0.8354 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D22 compound treatment 446880.0 25800.0 0.15 312390.0 -49900.0 -0.29 -0.1021 -0.3154 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D23 compound treatment 389980.0 -31100.0 -0.18 348760.0 -13500.0 -0.08 -0.1795 -0.9345 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 D24 compound treatment 449400.0 28300.0 0.16 442030.0 79700.0 0.46 0.4396 0.8988 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E01 mock treatment 530950.0 110000.0 0.62 435270.0 73000.0 0.42 0.7365 0.9829 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E02 mock treatment 549360.0 128000.0 0.72 382830.0 20500.0 0.12 0.5947 0.8127 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E03 compound treatment 455400.0 34300.0 0.19 313000.0 -49300.0 -0.29 -0.0657 -0.1904 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E04 compound treatment 495290.0 74200.0 0.42 456060.0 93800.0 0.54 0.6798 0.9915 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E05 compound treatment 270680.0 -150000.0 -0.85 381010.0 18700.0 0.11 -0.5221 -0.6115 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E06 compound treatment 468220.0 47100.0 0.27 400710.0 38400.0 0.22 0.345 0.9962 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E07 compound treatment 515470.0 94400.0 0.53 270460.0 -91800.0 -0.53 -0.001 -0.0014 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E08 compound treatment 431200.0 10100.0 0.06 325610.0 -36700.0 -0.21 -0.1103 -0.5008 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E09 mock treatment 561500.0 140000.0 0.79 466790.0 104000.0 0.61 0.9873 0.9914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E10 mock treatment 507160.0 86000.0 0.48 437600.0 75300.0 0.44 0.6513 0.9987 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E11 compound treatment 496840.0 75700.0 0.43 303460.0 -58800.0 -0.34 0.0601 0.1101 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E12 compound treatment 256960.0 -164000.0 -0.92 335390.0 -26900.0 -0.16 -0.7638 -0.815 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E13 compound treatment 351230.0 -69900.0 -0.39 388650.0 26300.0 0.15 -0.1701 -0.4031 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E14 compound treatment 481120.0 60000.0 0.34 314720.0 -47600.0 -0.28 0.0437 0.1003 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E15 compound treatment 387370.0 -33700.0 -0.19 361060.0 -1240.0 -0.01 -0.1394 -0.7334 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E16 compound treatment 293120.0 -128000.0 -0.72 369360.0 7060.0 0.04 -0.4806 -0.6659 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E17 mock treatment 554560.0 133000.0 0.75 349680.0 -12600.0 -0.07 0.4794 0.6352 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E18 mock treatment 540250.0 119000.0 0.67 443710.0 81400.0 0.47 0.8081 0.9852 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E19 compound treatment 370720.0 -50400.0 -0.28 290670.0 -71600.0 -0.42 -0.4943 -0.9827 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E20 compound treatment 388380.0 -32700.0 -0.18 383070.0 20800.0 0.12 -0.0451 -0.205 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E21 compound treatment 416160.0 -4950.0 -0.03 307360.0 -54900.0 -0.32 -0.245 -0.766 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E22 compound treatment 288350.0 -133000.0 -0.75 244270.0 -118000.0 -0.68 -1.0125 -0.999 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E23 compound treatment 310750.0 -110000.0 -0.62 262080.0 -100000.0 -0.58 -0.8503 -0.9994 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 E24 compound treatment 368020.0 -53100.0 -0.3 450080.0 87800.0 0.51 0.1486 0.2518 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F01 mock treatment 370740.0 -50400.0 -0.28 301460.0 -60800.0 -0.35 -0.45 -0.9941 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F02 mock treatment 407360.0 -13800.0 -0.08 285280.0 -77000.0 -0.45 -0.3706 -0.8175 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F03 compound treatment 241850.0 -179000.0 -1.01 328030.0 -34300.0 -0.2 -0.8541 -0.8304 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F04 compound treatment 290400.0 -131000.0 -0.74 300170.0 -62100.0 -0.36 -0.7751 -0.946 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F05 compound treatment 275770.0 -145000.0 -0.82 361290.0 -1010.0 -0.01 -0.5827 -0.7122 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F06 compound treatment 469630.0 48500.0 0.27 280320.0 -82000.0 -0.48 -0.1431 -0.2609 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F07 compound treatment 506580.0 85500.0 0.48 319620.0 -42700.0 -0.25 0.1652 0.3053 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F08 compound treatment 456720.0 35600.0 0.2 363090.0 786.0 0.0 0.145 0.723 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F09 mock treatment 373170.0 -47900.0 -0.27 437150.0 74800.0 0.43 0.1161 0.2271 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F10 mock treatment 495430.0 74300.0 0.42 238560.0 -124000.0 -0.72 -0.2116 -0.2547 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F11 compound treatment 376990.0 -44100.0 -0.25 332990.0 -29300.0 -0.17 -0.2958 -0.9829 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F12 compound treatment 510000.0 88900.0 0.5 469840.0 108000.0 0.62 0.7948 0.994 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F13 compound treatment 417770.0 -3340.0 -0.02 352170.0 -10100.0 -0.06 -0.0549 -0.889 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F14 compound treatment 543010.0 122000.0 0.69 460210.0 97900.0 0.57 0.8867 0.9956 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F15 compound treatment 434590.0 13500.0 0.08 298050.0 -64300.0 -0.37 -0.2098 -0.5518 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F16 compound treatment 399840.0 -21300.0 -0.12 464740.0 102000.0 0.59 0.3354 0.5534 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F17 mock treatment 269050.0 -152000.0 -0.86 481920.0 120000.0 0.69 -0.1148 -0.1042 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F18 mock treatment 429870.0 8760.0 0.05 390530.0 28200.0 0.16 0.1506 0.881 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F19 compound treatment 401440.0 -19700.0 -0.11 299870.0 -62400.0 -0.36 -0.3343 -0.883 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F20 compound treatment 429190.0 8080.0 0.05 308990.0 -53300.0 -0.31 -0.1865 -0.5967 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F21 compound treatment 379700.0 -41400.0 -0.23 301720.0 -60600.0 -0.35 -0.4133 -0.9801 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F22 compound treatment 331840.0 -89300.0 -0.5 306910.0 -55400.0 -0.32 -0.5825 -0.9766 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F23 compound treatment 388960.0 -32200.0 -0.18 233320.0 -129000.0 -0.75 -0.6569 -0.8536 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 F24 compound treatment 414880.0 -6230.0 -0.04 349560.0 -12700.0 -0.07 -0.0771 -0.942 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G01 compound treatment 371890.0 -49200.0 -0.28 275040.0 -87300.0 -0.51 -0.5538 -0.9598 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G02 compound treatment 326450.0 -94700.0 -0.53 294720.0 -67600.0 -0.39 -0.654 -0.9886 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G03 mock treatment 272810.0 -148000.0 -0.83 349820.0 -12500.0 -0.07 -0.6415 -0.7656 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G04 mock treatment 349330.0 -71800.0 -0.4 393310.0 31000.0 0.18 -0.1586 -0.3586 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G05 compound treatment 510800.0 89700.0 0.5 348450.0 -13900.0 -0.08 0.3002 0.5872 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G06 compound treatment 253440.0 -168000.0 -0.94 220480.0 -142000.0 -0.82 -1.249 -0.9976 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G07 compound treatment 283650.0 -137000.0 -0.77 193440.0 -169000.0 -0.98 -1.2397 -0.9932 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G08 compound treatment 343160.0 -78000.0 -0.44 375300.0 13000.0 0.08 -0.257 -0.5772 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G09 compound treatment 471540.0 50400.0 0.28 391520.0 29200.0 0.17 0.3206 0.9696 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G10 compound treatment 448930.0 27800.0 0.16 297500.0 -64800.0 -0.38 -0.155 -0.3807 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G11 compound treatment 317870.0 -103000.0 -0.58 475000.0 113000.0 0.65 0.0512 0.0585 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G12 compound treatment 192680.0 -228000.0 -1.29 182080.0 -180000.0 -1.05 -1.6484 -0.9947 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G13 compound treatment 367270.0 -53800.0 -0.3 391200.0 28900.0 0.17 -0.0958 -0.2767 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G14 compound treatment 257280.0 -164000.0 -0.92 302050.0 -60300.0 -0.35 -0.8992 -0.9118 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G15 compound treatment 309760.0 -111000.0 -0.63 404800.0 42500.0 0.25 -0.269 -0.3993 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G16 compound treatment 346560.0 -74600.0 -0.42 389850.0 27500.0 0.16 -0.1838 -0.4093 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G17 compound treatment 555840.0 135000.0 0.76 330720.0 -31600.0 -0.18 0.4068 0.5214 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G18 compound treatment 390580.0 -30500.0 -0.17 314080.0 -48200.0 -0.28 -0.3193 -0.9727 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G19 mock treatment 371070.0 -50000.0 -0.28 425710.0 63400.0 0.37 0.0608 0.1313 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G20 mock treatment 342310.0 -78800.0 -0.44 316810.0 -45500.0 -0.26 -0.5002 -0.9692 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G21 compound treatment 322480.0 -98600.0 -0.56 365970.0 3670.0 0.02 -0.3776 -0.6795 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G22 compound treatment 415100.0 -6010.0 -0.03 267480.0 -94800.0 -0.55 -0.4128 -0.7492 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G23 compound treatment 378610.0 -42500.0 -0.24 370490.0 8190.0 0.05 -0.1356 -0.556 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 G24 compound treatment 448710.0 27600.0 0.16 341440.0 -20900.0 -0.12 0.0243 0.1234 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H01 compound treatment 111810.0 -309000.0 -1.74 470150.0 108000.0 0.63 -0.789 -0.4264 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H02 compound treatment 367860.0 -53300.0 -0.3 403840.0 41500.0 0.24 -0.0416 -0.1083 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H03 mock treatment 346160.0 -75000.0 -0.42 447590.0 85300.0 0.49 0.0514 0.079 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H04 mock treatment 527200.0 106000.0 0.6 454980.0 92700.0 0.54 0.8024 0.9986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H05 compound treatment 296160.0 -125000.0 -0.7 394330.0 32000.0 0.19 -0.3661 -0.5032 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H06 compound treatment 528080.0 107000.0 0.6 378320.0 16000.0 0.09 0.4915 0.8066 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H07 compound treatment 324170.0 -96900.0 -0.55 337550.0 -24800.0 -0.14 -0.4874 -0.8637 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H08 compound treatment 277700.0 -143000.0 -0.81 371080.0 8780.0 0.05 -0.5349 -0.6612 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H09 compound treatment 328580.0 -92500.0 -0.52 290810.0 -71500.0 -0.41 -0.6615 -0.9936 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H10 compound treatment 367390.0 -53700.0 -0.3 548840.0 187000.0 1.08 0.5511 0.4906 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H11 compound treatment 212730.0 -208000.0 -1.17 317800.0 -44500.0 -0.26 -1.012 -0.8425 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H12 compound treatment 552560.0 131000.0 0.74 146880.0 -215000.0 -1.25 -0.3602 -0.248 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H13 compound treatment 406850.0 -14300.0 -0.08 390260.0 28000.0 0.16 0.0579 0.3199 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H14 compound treatment 480690.0 59600.0 0.34 466040.0 104000.0 0.6 0.6626 0.9619 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H15 compound treatment 352520.0 -68600.0 -0.39 382290.0 20000.0 0.12 -0.1911 -0.474 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H16 compound treatment 511630.0 90500.0 0.51 450720.0 88400.0 0.51 0.7229 1.0 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H17 compound treatment 408510.0 -12600.0 -0.07 407090.0 44800.0 0.26 0.1335 0.4958 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H18 compound treatment 401820.0 -19300.0 -0.11 492160.0 130000.0 0.75 0.4557 0.5989 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H19 mock treatment 392130.0 -29000.0 -0.16 382160.0 19900.0 0.12 -0.0339 -0.1699 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H20 mock treatment 473490.0 52400.0 0.29 461780.0 99500.0 0.58 0.6164 0.9514 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H21 compound treatment 286410.0 -135000.0 -0.76 340870.0 -21400.0 -0.12 -0.6241 -0.8122 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H22 compound treatment 403010.0 -18100.0 -0.1 246290.0 -116000.0 -0.67 -0.5478 -0.805 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H23 compound treatment 412420.0 -8690.0 -0.05 268320.0 -94000.0 -0.55 -0.42 -0.7675 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 H24 compound treatment 413330.0 -7780.0 -0.04 347650.0 -14700.0 -0.08 -0.0911 -0.9525 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I01 compound treatment 251300.0 -170000.0 -0.96 456800.0 94500.0 0.55 -0.2885 -0.2618 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I02 compound treatment 423650.0 2540.0 0.01 394970.0 32700.0 0.19 0.1441 0.7583 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I03 compound treatment 234080.0 -187000.0 -1.05 407720.0 45400.0 0.26 -0.5583 -0.5144 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I04 compound treatment 309120.0 -112000.0 -0.63 254140.0 -108000.0 -0.63 -0.8894 -1.0 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I05 mock treatment 355170.0 -65900.0 -0.37 240810.0 -121000.0 -0.7 -0.7607 -0.9552 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I06 mock treatment 211730.0 -209000.0 -1.18 352050.0 -10300.0 -0.06 -0.8755 -0.7418 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I07 compound treatment 472910.0 51800.0 0.29 259860.0 -102000.0 -0.59 -0.2139 -0.3232 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I08 compound treatment 504710.0 83600.0 0.47 317920.0 -44400.0 -0.26 0.1508 0.2811 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I09 compound treatment 489970.0 68900.0 0.39 353050.0 -9250.0 -0.05 0.2362 0.6035 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I10 compound treatment 458490.0 37400.0 0.21 363960.0 1660.0 0.01 0.1556 0.7386 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I11 compound treatment 360640.0 -60500.0 -0.34 460810.0 98500.0 0.57 0.1632 0.2455 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I12 compound treatment 331700.0 -89400.0 -0.5 342750.0 -19600.0 -0.11 -0.4361 -0.8452 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I13 compound treatment 468120.0 47000.0 0.26 471010.0 109000.0 0.63 0.6329 0.9257 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I14 compound treatment 373920.0 -47200.0 -0.27 411200.0 48900.0 0.28 0.0127 0.0326 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I15 compound treatment 458080.0 37000.0 0.21 449870.0 87600.0 0.51 0.5063 0.9224 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I16 compound treatment 467290.0 46200.0 0.26 316590.0 -45700.0 -0.27 -0.0036 -0.0098 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I17 compound treatment 474760.0 53600.0 0.3 304930.0 -57400.0 -0.33 -0.0217 -0.0483 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I18 compound treatment 408650.0 -12500.0 -0.07 449330.0 87000.0 0.5 0.3073 0.603 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I19 compound treatment 434780.0 13700.0 0.08 308260.0 -54000.0 -0.31 -0.1672 -0.5181 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I20 compound treatment 347320.0 -73800.0 -0.42 353500.0 -8800.0 -0.05 -0.3298 -0.7881 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I21 mock treatment 387810.0 -33300.0 -0.19 431570.0 69300.0 0.4 0.1515 0.3417 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I22 mock treatment 388900.0 -32200.0 -0.18 390280.0 28000.0 0.16 -0.0135 -0.0555 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I23 compound treatment 403750.0 -17400.0 -0.1 415680.0 53400.0 0.31 0.1498 0.4614 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 I24 compound treatment 414630.0 -6480.0 -0.04 313310.0 -49000.0 -0.28 -0.2267 -0.7914 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J01 compound treatment 229610.0 -192000.0 -1.08 220110.0 -142000.0 -0.82 -1.3454 -0.9912 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J02 compound treatment 281660.0 -139000.0 -0.79 269120.0 -93200.0 -0.54 -0.9372 -0.9834 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J03 compound treatment 291170.0 -130000.0 -0.73 376290.0 14000.0 0.08 -0.4599 -0.6249 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J04 compound treatment 376550.0 -44600.0 -0.25 348190.0 -14100.0 -0.08 -0.2353 -0.8916 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J05 mock treatment 460710.0 39600.0 0.22 248320.0 -114000.0 -0.66 -0.3098 -0.4441 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J06 mock treatment 164420.0 -257000.0 -1.45 231720.0 -131000.0 -0.76 -1.5573 -0.9545 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J07 compound treatment 325400.0 -95700.0 -0.54 251270.0 -111000.0 -0.64 -0.8363 -0.9961 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J08 compound treatment 466040.0 44900.0 0.25 296500.0 -65800.0 -0.38 -0.091 -0.1988 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J09 compound treatment 378970.0 -42100.0 -0.24 432800.0 70500.0 0.41 0.1213 0.2567 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J10 compound treatment 329060.0 -92100.0 -0.52 259270.0 -103000.0 -0.6 -0.7889 -0.9975 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J11 compound treatment 471310.0 50200.0 0.28 237540.0 -125000.0 -0.72 -0.3118 -0.4014 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J12 compound treatment 397620.0 -23500.0 -0.13 353600.0 -8700.0 -0.05 -0.1292 -0.9128 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J13 compound treatment 502920.0 81800.0 0.46 313350.0 -49000.0 -0.28 0.1249 0.2309 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J14 compound treatment 504180.0 83100.0 0.47 363490.0 1190.0 0.01 0.3355 0.7174 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J15 compound treatment 449090.0 28000.0 0.16 350590.0 -11700.0 -0.07 0.0633 0.3692 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J16 compound treatment 470830.0 49700.0 0.28 283200.0 -79100.0 -0.46 -0.1265 -0.2353 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J17 compound treatment 428440.0 7330.0 0.04 429860.0 67600.0 0.39 0.3062 0.7773 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J18 compound treatment 339950.0 -81200.0 -0.46 259140.0 -103000.0 -0.6 -0.7461 -0.9911 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J19 compound treatment 368370.0 -52700.0 -0.3 295520.0 -66800.0 -0.39 -0.4838 -0.9914 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J20 compound treatment 267070.0 -154000.0 -0.87 304510.0 -57800.0 -0.34 -0.8502 -0.9145 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J21 mock treatment 365300.0 -55800.0 -0.31 341830.0 -20500.0 -0.12 -0.3061 -0.9114 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J22 mock treatment 355750.0 -65400.0 -0.37 284160.0 -78100.0 -0.45 -0.5806 -0.9947 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J23 compound treatment 306790.0 -114000.0 -0.64 288880.0 -73400.0 -0.43 -0.7562 -0.9799 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 J24 compound treatment 301930.0 -119000.0 -0.67 323300.0 -39000.0 -0.23 -0.6344 -0.896 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K01 compound treatment 449980.0 28900.0 0.16 453300.0 91000.0 0.53 0.4881 0.8839 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K02 compound treatment 188400.0 -233000.0 -1.31 364720.0 2420.0 0.01 -0.9164 -0.6995 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K03 compound treatment 517620.0 96500.0 0.54 473320.0 111000.0 0.64 0.8394 0.9964 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K04 compound treatment 281760.0 -139000.0 -0.78 419200.0 56900.0 0.33 -0.3214 -0.3776 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K05 compound treatment 265690.0 -155000.0 -0.87 194760.0 -168000.0 -0.97 -1.3057 -0.9986 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K06 compound treatment 302950.0 -118000.0 -0.67 314720.0 -47600.0 -0.28 -0.6655 -0.9241 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K07 mock treatment 397600.0 -23500.0 -0.13 414570.0 52300.0 0.3 0.1207 0.3651 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K08 mock treatment 558900.0 138000.0 0.78 312410.0 -49900.0 -0.29 0.3439 0.4154 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K09 compound treatment 429920.0 8810.0 0.05 272500.0 -89800.0 -0.52 -0.3332 -0.6369 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K10 compound treatment 372340.0 -48800.0 -0.27 272060.0 -90200.0 -0.52 -0.5642 -0.9547 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K11 compound treatment 269940.0 -151000.0 -0.85 306360.0 -55900.0 -0.32 -0.8312 -0.9126 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K12 compound treatment 393680.0 -27400.0 -0.15 240690.0 -122000.0 -0.71 -0.6079 -0.842 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K13 compound treatment 423840.0 2730.0 0.02 306630.0 -55700.0 -0.32 -0.2174 -0.6727 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K14 compound treatment 487360.0 66200.0 0.37 343370.0 -18900.0 -0.11 0.1861 0.4786 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K15 mock treatment 415280.0 -5830.0 -0.03 337120.0 -25200.0 -0.15 -0.1265 -0.8449 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K16 mock treatment 453060.0 31900.0 0.18 277760.0 -84500.0 -0.49 -0.2195 -0.4203 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K17 compound treatment 530890.0 110000.0 0.62 403380.0 41100.0 0.24 0.6054 0.9141 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K18 compound treatment 348030.0 -73100.0 -0.41 358350.0 -3950.0 -0.02 -0.3071 -0.7454 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K19 compound treatment 332640.0 -88500.0 -0.5 450160.0 87900.0 0.51 0.0081 0.0114 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K20 compound treatment 392090.0 -29000.0 -0.16 365000.0 2700.0 0.02 -0.1045 -0.6365 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K21 compound treatment 437700.0 16600.0 0.09 333610.0 -28700.0 -0.17 -0.0516 -0.2706 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K22 compound treatment 333410.0 -87700.0 -0.49 365180.0 2880.0 0.02 -0.3373 -0.6828 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K23 mock treatment 374340.0 -46800.0 -0.26 346990.0 -15300.0 -0.09 -0.249 -0.896 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 K24 mock treatment 410480.0 -10600.0 -0.06 440690.0 78400.0 0.45 0.2791 0.6088 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L01 compound treatment 405570.0 -15500.0 -0.09 215050.0 -147000.0 -0.85 -0.6657 -0.7755 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L02 compound treatment 500430.0 79300.0 0.45 545480.0 183000.0 1.06 1.0669 0.9259 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L03 compound treatment 386930.0 -34200.0 -0.19 249050.0 -113000.0 -0.66 -0.6005 -0.8774 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L04 compound treatment 493160.0 72000.0 0.41 445930.0 83600.0 0.48 0.6297 0.9961 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L05 compound treatment 401620.0 -19500.0 -0.11 370360.0 8060.0 0.05 -0.0446 -0.3736 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L06 compound treatment 301060.0 -120000.0 -0.68 353240.0 -9060.0 -0.05 -0.5151 -0.7598 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L07 mock treatment 474110.0 53000.0 0.3 256040.0 -106000.0 -0.62 -0.2248 -0.3283 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L08 mock treatment 378580.0 -42500.0 -0.24 396680.0 34400.0 0.2 -0.0283 -0.0909 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L09 compound treatment 249600.0 -172000.0 -0.97 386030.0 23700.0 0.14 -0.5854 -0.6003 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L10 compound treatment 530690.0 110000.0 0.62 347250.0 -15100.0 -0.09 0.3745 0.601 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L11 compound treatment 297130.0 -124000.0 -0.7 271140.0 -91200.0 -0.53 -0.8674 -0.9906 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L12 compound treatment 512120.0 91000.0 0.51 513760.0 151000.0 0.88 0.9834 0.9671 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L13 compound treatment 482080.0 61000.0 0.34 322890.0 -39400.0 -0.23 0.0811 0.1966 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L14 compound treatment 555550.0 134000.0 0.76 492250.0 130000.0 0.75 1.068 1.0 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L15 mock treatment 473760.0 52600.0 0.3 375040.0 12700.0 0.07 0.2618 0.8571 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L16 mock treatment 439570.0 18500.0 0.1 267900.0 -94400.0 -0.55 -0.3137 -0.5628 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L17 compound treatment 521030.0 99900.0 0.56 374240.0 11900.0 0.07 0.4467 0.7882 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L18 compound treatment 452830.0 31700.0 0.18 256260.0 -106000.0 -0.61 -0.3086 -0.4819 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L19 compound treatment 294610.0 -127000.0 -0.71 430980.0 68700.0 0.4 -0.2219 -0.272 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L20 compound treatment 379520.0 -41600.0 -0.23 341950.0 -20400.0 -0.12 -0.249 -0.9497 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L21 compound treatment 333060.0 -88100.0 -0.5 296550.0 -65800.0 -0.38 -0.6201 -0.9916 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L22 compound treatment 436670.0 15600.0 0.09 383480.0 21200.0 0.12 0.1488 0.9863 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L23 mock treatment 424060.0 2950.0 0.02 383330.0 21000.0 0.12 0.098 0.7961 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 L24 mock treatment 473400.0 52300.0 0.29 354240.0 -8060.0 -0.05 0.1751 0.5874 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M01 compound treatment 333610.0 -87500.0 -0.49 193850.0 -168000.0 -0.98 -1.0391 -0.9497 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M02 compound treatment 425020.0 3910.0 0.02 304480.0 -57800.0 -0.34 -0.2216 -0.6593 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M03 compound treatment 415000.0 -6110.0 -0.03 258630.0 -104000.0 -0.6 -0.4495 -0.7463 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M04 compound treatment 389700.0 -31400.0 -0.18 411080.0 48800.0 0.28 0.075 0.2248 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M05 compound treatment 263620.0 -157000.0 -0.89 259520.0 -103000.0 -0.6 -1.0484 -0.9813 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M06 compound treatment 370750.0 -50400.0 -0.28 284070.0 -78200.0 -0.45 -0.5213 -0.9744 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M07 compound treatment 369610.0 -51500.0 -0.29 194790.0 -168000.0 -0.97 -0.892 -0.8798 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M08 compound treatment 196560.0 -225000.0 -1.26 257030.0 -105000.0 -0.61 -1.3256 -0.9443 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M09 mock treatment 446820.0 25700.0 0.14 382720.0 20400.0 0.12 0.1861 0.995 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M10 mock treatment 343520.0 -77600.0 -0.44 299710.0 -62600.0 -0.36 -0.5655 -0.9958 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M11 compound treatment 422590.0 1480.0 0.01 269400.0 -92900.0 -0.54 -0.3751 -0.6961 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M12 compound treatment 323360.0 -97800.0 -0.55 404540.0 42200.0 0.24 -0.2159 -0.3585 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M13 mock treatment 452540.0 31400.0 0.18 495090.0 133000.0 0.77 0.6696 0.8475 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M14 mock treatment 486780.0 65700.0 0.37 356500.0 -5800.0 -0.03 0.2376 0.6401 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M15 compound treatment 408840.0 -12300.0 -0.07 392220.0 29900.0 0.17 0.0738 0.3954 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M16 compound treatment 356550.0 -64600.0 -0.36 227440.0 -135000.0 -0.78 -0.81 -0.9392 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M17 compound treatment 472160.0 51000.0 0.29 310010.0 -52300.0 -0.3 -0.0112 -0.0269 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M18 compound treatment 414330.0 -6780.0 -0.04 326720.0 -35600.0 -0.21 -0.1729 -0.8239 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M19 compound treatment 396820.0 -24300.0 -0.14 357870.0 -4430.0 -0.03 -0.1149 -0.8256 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M20 compound treatment 382990.0 -38100.0 -0.21 431850.0 69500.0 0.4 0.1334 0.2921 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M21 compound treatment 395440.0 -25700.0 -0.14 374650.0 12300.0 0.07 -0.0516 -0.3197 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M22 compound treatment 412420.0 -8690.0 -0.05 345000.0 -17300.0 -0.1 -0.1056 -0.9455 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M23 compound treatment 398240.0 -22900.0 -0.13 329010.0 -33300.0 -0.19 -0.2276 -0.9806 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 M24 compound treatment 424040.0 2930.0 0.02 312510.0 -49800.0 -0.29 -0.1925 -0.6656 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N01 compound treatment 156410.0 -265000.0 -1.49 328560.0 -33700.0 -0.2 -1.1921 -0.7932 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N02 compound treatment 505440.0 84300.0 0.47 366470.0 4170.0 0.02 0.3528 0.7421 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N03 compound treatment 369690.0 -51400.0 -0.29 312730.0 -49600.0 -0.29 -0.408 -1.0 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N04 compound treatment 526210.0 105000.0 0.59 512570.0 150000.0 0.87 1.0346 0.9822 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N05 compound treatment 435080.0 14000.0 0.08 448480.0 86200.0 0.5 0.409 0.8084 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N06 compound treatment 511290.0 90200.0 0.51 362730.0 426.0 0.0 0.3607 0.7105 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N07 compound treatment 500280.0 79200.0 0.45 277290.0 -85000.0 -0.49 -0.0335 -0.0504 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N08 compound treatment 380200.0 -40900.0 -0.23 283960.0 -78300.0 -0.45 -0.4841 -0.9504 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N09 mock treatment 408640.0 -12500.0 -0.07 380420.0 18100.0 0.11 0.0246 0.1951 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N10 mock treatment 451790.0 30700.0 0.17 342350.0 -20000.0 -0.12 0.0403 0.1938 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N11 compound treatment 443680.0 22600.0 0.13 303200.0 -59100.0 -0.34 -0.1525 -0.4173 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N12 compound treatment 457300.0 36200.0 0.2 270560.0 -91700.0 -0.53 -0.2322 -0.4075 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N13 mock treatment 404380.0 -16700.0 -0.09 268810.0 -93500.0 -0.54 -0.45 -0.8177 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N14 mock treatment 339330.0 -81800.0 -0.46 463050.0 101000.0 0.58 0.0876 0.1178 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N15 compound treatment 486240.0 65100.0 0.37 425080.0 62800.0 0.36 0.5167 1.0 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N16 compound treatment 585620.0 165000.0 0.93 457870.0 95600.0 0.55 1.0468 0.9699 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N17 compound treatment 378890.0 -42200.0 -0.24 388640.0 26300.0 0.15 -0.0601 -0.2126 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N18 compound treatment 452800.0 31700.0 0.18 447200.0 84900.0 0.49 0.4743 0.9057 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N19 compound treatment 470940.0 49800.0 0.28 355610.0 -6690.0 -0.04 0.1709 0.6035 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N20 compound treatment 494570.0 73500.0 0.41 368580.0 6280.0 0.04 0.3182 0.7664 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N21 compound treatment 317020.0 -104000.0 -0.59 295130.0 -67200.0 -0.39 -0.6898 -0.9803 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N22 compound treatment 427520.0 6410.0 0.04 351920.0 -10400.0 -0.06 -0.0171 -0.2431 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N23 compound treatment 471750.0 50600.0 0.29 391750.0 29400.0 0.17 0.3223 0.97 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 N24 compound treatment 443460.0 22300.0 0.13 344800.0 -17500.0 -0.1 0.0172 0.1063 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O01 compound treatment 230450.0 -191000.0 -1.07 190140.0 -172000.0 -1.0 -1.465 -0.9993 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O02 compound treatment 448000.0 26900.0 0.15 412700.0 50400.0 0.29 0.3137 0.9531 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O03 compound treatment 457730.0 36600.0 0.21 284390.0 -77900.0 -0.45 -0.1737 -0.3498 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O04 compound treatment 290080.0 -131000.0 -0.74 365570.0 3270.0 0.02 -0.5082 -0.6887 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O05 compound treatment 276190.0 -145000.0 -0.82 269640.0 -92700.0 -0.54 -0.9569 -0.9795 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O06 compound treatment 321220.0 -99900.0 -0.56 230820.0 -131000.0 -0.76 -0.9368 -0.9888 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O07 compound treatment 379120.0 -42000.0 -0.24 408850.0 46500.0 0.27 0.0237 0.0661 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O08 compound treatment 329680.0 -91400.0 -0.51 217470.0 -145000.0 -0.84 -0.9579 -0.9724 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O09 compound treatment 371160.0 -50000.0 -0.28 429210.0 66900.0 0.39 0.0755 0.1576 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O10 compound treatment 290900.0 -130000.0 -0.73 399200.0 36900.0 0.21 -0.367 -0.4806 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O11 mock treatment 526160.0 105000.0 0.59 448900.0 86600.0 0.5 0.7733 0.9967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O12 mock treatment 452080.0 31000.0 0.17 380000.0 17700.0 0.1 0.1958 0.9681 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O13 compound treatment 383680.0 -37400.0 -0.21 318040.0 -44300.0 -0.26 -0.3305 -0.9952 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O14 compound treatment 363290.0 -57800.0 -0.33 218830.0 -143000.0 -0.83 -0.8185 -0.9161 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O15 compound treatment 460290.0 39200.0 0.22 404970.0 42700.0 0.25 0.3309 0.9984 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O16 compound treatment 404770.0 -16300.0 -0.09 378280.0 16000.0 0.09 5.0E-4 0.0036 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O17 compound treatment 237840.0 -183000.0 -1.03 399390.0 37100.0 0.22 -0.5775 -0.5479 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O18 compound treatment 426210.0 5100.0 0.03 413690.0 51400.0 0.3 0.231 0.7717 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O19 compound treatment 425030.0 3920.0 0.02 338280.0 -24000.0 -0.14 -0.0829 -0.5878 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O20 compound treatment 326690.0 -94400.0 -0.53 347300.0 -15000.0 -0.09 -0.4374 -0.8121 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O21 compound treatment 386580.0 -34500.0 -0.19 333220.0 -29100.0 -0.17 -0.2567 -0.9975 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O22 compound treatment 410780.0 -10300.0 -0.06 324090.0 -38200.0 -0.22 -0.1978 -0.8634 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O23 compound treatment 439290.0 18200.0 0.1 386790.0 24500.0 0.14 0.1728 0.9871 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 O24 compound treatment 447920.0 26800.0 0.15 337250.0 -25100.0 -0.15 0.004 0.019 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P01 compound treatment 230350.0 -191000.0 -1.07 314190.0 -48100.0 -0.28 -0.9567 -0.8622 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P02 compound treatment 355330.0 -65800.0 -0.37 304670.0 -57600.0 -0.33 -0.4982 -0.9987 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P03 compound treatment 246940.0 -174000.0 -0.98 224510.0 -138000.0 -0.8 -1.2584 -0.9948 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P04 compound treatment 250000.0 -171000.0 -0.96 240990.0 -121000.0 -0.7 -1.1786 -0.9881 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P05 compound treatment 405920.0 -15200.0 -0.09 214100.0 -148000.0 -0.86 -0.6682 -0.7736 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P06 compound treatment 317630.0 -103000.0 -0.58 327540.0 -34800.0 -0.2 -0.5545 -0.8995 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P07 compound treatment 365790.0 -55300.0 -0.31 187360.0 -175000.0 -1.01 -0.9376 -0.8835 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P08 compound treatment 391210.0 -29900.0 -0.17 421840.0 59500.0 0.35 0.1251 0.3257 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P09 compound treatment 239010.0 -182000.0 -1.03 268490.0 -93800.0 -0.54 -1.1096 -0.9561 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P10 compound treatment 318250.0 -103000.0 -0.58 283070.0 -79200.0 -0.46 -0.7344 -0.9934 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P11 mock treatment 397440.0 -23700.0 -0.13 386580.0 24300.0 0.14 0.0053 0.0275 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P12 mock treatment 328070.0 -93000.0 -0.52 280130.0 -82200.0 -0.48 -0.7073 -0.9989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P13 compound treatment 302200.0 -119000.0 -0.67 420560.0 58300.0 0.34 -0.2344 -0.3127 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P14 compound treatment 329510.0 -91600.0 -0.52 308650.0 -53700.0 -0.31 -0.5847 -0.9707 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P15 compound treatment 212490.0 -209000.0 -1.17 224240.0 -138000.0 -0.8 -1.3966 -0.9826 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P16 compound treatment 423640.0 2530.0 0.01 307100.0 -55200.0 -0.32 -0.2163 -0.675 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P17 compound treatment 297640.0 -123000.0 -0.7 291650.0 -70700.0 -0.41 -0.7812 -0.9682 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P18 compound treatment 467940.0 46800.0 0.26 286650.0 -75700.0 -0.44 -0.1238 -0.2419 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P19 compound treatment 366040.0 -55100.0 -0.31 328200.0 -34100.0 -0.2 -0.3591 -0.9764 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P20 compound treatment 306590.0 -115000.0 -0.64 364590.0 2290.0 0.01 -0.4465 -0.6924 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P21 compound treatment 406360.0 -14800.0 -0.08 323320.0 -39000.0 -0.23 -0.2186 -0.9075 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P22 compound treatment 340180.0 -80900.0 -0.46 312480.0 -49800.0 -0.29 -0.5265 -0.9759 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P23 compound treatment 317720.0 -103000.0 -0.58 271300.0 -91000.0 -0.53 -0.7848 -0.9988 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2101 P24 compound treatment 393560.0 -27600.0 -0.16 327130.0 -35200.0 -0.2 -0.2539 -0.9909 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A01 compound treatment 180910.0 -279000.0 -1.57 294320.0 -142000.0 -0.82 -1.6914 -0.9549 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A02 compound treatment 88320.0 -371000.0 -2.09 102030.0 -334000.0 -1.94 -2.8485 -0.9993 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A03 compound treatment 190370.0 -269000.0 -1.51 173350.0 -263000.0 -1.53 -2.1499 -1.0 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A04 compound treatment 240160.0 -219000.0 -1.23 397570.0 -38800.0 -0.23 -1.0322 -0.8225 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A05 compound treatment 455590.0 -3870.0 -0.02 192050.0 -244000.0 -1.42 -1.0174 -0.7179 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A06 compound treatment 96380.0 -363000.0 -2.04 359650.0 -76700.0 -0.45 -1.76 -0.8414 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A07 compound treatment 419570.0 -39900.0 -0.22 201620.0 -235000.0 -1.36 -1.1216 -0.8127 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A08 compound treatment 152600.0 -307000.0 -1.73 76740.0 -360000.0 -2.09 -2.6964 -0.9956 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A09 compound treatment 138820.0 -321000.0 -1.81 232870.0 -204000.0 -1.18 -2.111 -0.9788 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A10 compound treatment 238350.0 -221000.0 -1.24 149550.0 -287000.0 -1.66 -2.0565 -0.9898 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A11 compound treatment 218820.0 -241000.0 -1.35 219040.0 -217000.0 -1.26 -1.8492 -0.9994 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A12 compound treatment 147280.0 -312000.0 -1.76 233400.0 -203000.0 -1.18 -2.0751 -0.981 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A13 mock treatment 217650.0 -242000.0 -1.36 276800.0 -160000.0 -0.93 -1.617 -0.9823 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A14 mock treatment 329920.0 -130000.0 -0.73 492190.0 55800.0 0.32 -0.2868 -0.3596 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A15 compound treatment 182590.0 -277000.0 -1.56 238470.0 -198000.0 -1.15 -1.9138 -0.9887 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A16 compound treatment 201720.0 -258000.0 -1.45 190630.0 -246000.0 -1.43 -2.0338 -1.0 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A17 compound treatment 96000.0 -363000.0 -2.05 135090.0 -301000.0 -1.75 -2.6824 -0.9969 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A18 compound treatment 97280.0 -362000.0 -2.04 100160.0 -336000.0 -1.95 -2.8206 -0.9998 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A19 compound treatment 162620.0 -297000.0 -1.67 152570.0 -284000.0 -1.65 -2.3455 -1.0 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A20 compound treatment 109380.0 -350000.0 -1.97 148080.0 -288000.0 -1.67 -2.5759 -0.9967 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A21 compound treatment 250520.0 -209000.0 -1.18 350430.0 -86000.0 -0.5 -1.1842 -0.927 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A22 compound treatment 211840.0 -248000.0 -1.39 147600.0 -289000.0 -1.67 -2.17 -0.9958 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A23 compound treatment 208320.0 -251000.0 -1.41 396120.0 -40300.0 -0.23 -1.1649 -0.8129 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 A24 compound treatment 279790.0 -180000.0 -1.01 381820.0 -54600.0 -0.32 -0.939 -0.886 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B01 compound treatment 238800.0 -221000.0 -1.24 462010.0 25600.0 0.15 -0.7733 -0.6182 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B02 compound treatment 192000.0 -267000.0 -1.51 310120.0 -126000.0 -0.73 -1.5825 -0.9452 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B03 compound treatment 555540.0 96100.0 0.54 600500.0 164000.0 0.95 1.0554 0.9642 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B04 compound treatment 242250.0 -217000.0 -1.22 274620.0 -162000.0 -0.94 -1.528 -0.9914 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B05 compound treatment 287950.0 -172000.0 -0.97 203240.0 -233000.0 -1.35 -1.6388 -0.9864 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B06 compound treatment 424390.0 -35100.0 -0.2 200160.0 -236000.0 -1.37 -1.1084 -0.8007 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B07 compound treatment 453000.0 -6460.0 -0.04 226880.0 -210000.0 -1.22 -0.8849 -0.7279 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B08 compound treatment 254480.0 -205000.0 -1.15 272420.0 -164000.0 -0.95 -1.4884 -0.9954 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B09 compound treatment 269630.0 -190000.0 -1.07 274200.0 -162000.0 -0.94 -1.4208 -0.998 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B10 compound treatment 267940.0 -192000.0 -1.08 229760.0 -207000.0 -1.2 -1.6097 -0.9986 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B11 compound treatment 189440.0 -270000.0 -1.52 317690.0 -119000.0 -0.69 -1.5616 -0.9359 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B12 compound treatment 151370.0 -308000.0 -1.73 201980.0 -234000.0 -1.36 -2.1877 -0.9927 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B13 mock treatment 504280.0 44800.0 0.25 464800.0 28400.0 0.16 0.2949 0.9786 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B14 mock treatment 467230.0 7780.0 0.04 404500.0 -31900.0 -0.18 -0.0999 -0.5253 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B15 compound treatment 237460.0 -222000.0 -1.25 301630.0 -135000.0 -0.78 -1.4363 -0.9745 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B16 compound treatment 266080.0 -193000.0 -1.09 309280.0 -127000.0 -0.74 -1.2911 -0.982 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B17 compound treatment 229390.0 -230000.0 -1.3 235410.0 -201000.0 -1.17 -1.74 -0.9986 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B18 compound treatment 279100.0 -180000.0 -1.02 326900.0 -109000.0 -0.64 -1.167 -0.9745 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B19 compound treatment 316400.0 -143000.0 -0.81 452610.0 16200.0 0.09 -0.503 -0.6203 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B20 compound treatment 383060.0 -76400.0 -0.43 351520.0 -84900.0 -0.49 -0.6522 -0.9977 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B21 compound treatment 398240.0 -61200.0 -0.34 400910.0 -35500.0 -0.21 -0.3892 -0.9696 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B22 compound treatment 252360.0 -207000.0 -1.17 253560.0 -183000.0 -1.06 -1.5742 -0.9989 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B23 compound treatment 301200.0 -158000.0 -0.89 362130.0 -74300.0 -0.43 -0.9345 -0.9444 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 B24 compound treatment 519900.0 60400.0 0.34 500440.0 64000.0 0.37 0.5032 0.999 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C01 compound treatment 307370.0 -152000.0 -0.86 400900.0 -35500.0 -0.21 -0.751 -0.8528 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C02 compound treatment 310320.0 -149000.0 -0.84 193090.0 -243000.0 -1.41 -1.5914 -0.9692 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C03 compound treatment 461210.0 1760.0 0.01 225920.0 -210000.0 -1.22 -0.8561 -0.7014 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C04 compound treatment 236070.0 -223000.0 -1.26 254140.0 -182000.0 -1.06 -1.6366 -0.9963 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C05 compound treatment 287860.0 -172000.0 -0.97 404590.0 -31800.0 -0.18 -0.8135 -0.8272 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C06 compound treatment 52240.0 -407000.0 -2.29 13240.0 -423000.0 -2.45 -3.3563 -0.9994 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C07 compound treatment 445720.0 -13700.0 -0.08 453050.0 16700.0 0.1 0.0136 0.11 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C08 compound treatment 223530.0 -236000.0 -1.33 190200.0 -246000.0 -1.43 -1.9488 -0.9993 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C09 compound treatment 240800.0 -219000.0 -1.23 289380.0 -147000.0 -0.85 -1.4733 -0.9839 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C10 compound treatment 210340.0 -249000.0 -1.4 82190.0 -354000.0 -2.05 -2.4442 -0.9827 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C11 mock treatment 293210.0 -166000.0 -0.94 544120.0 108000.0 0.62 -0.22 -0.1955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C12 mock treatment 495080.0 35600.0 0.2 378940.0 -57500.0 -0.33 -0.0938 -0.2412 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C13 compound treatment 473280.0 13800.0 0.08 215080.0 -221000.0 -1.28 -0.8526 -0.663 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C14 compound treatment 245440.0 -214000.0 -1.2 34720.0 -402000.0 -2.33 -2.4991 -0.9529 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C15 mock treatment 516970.0 57500.0 0.32 294240.0 -142000.0 -0.82 -0.354 -0.3997 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C16 mock treatment 407310.0 -52100.0 -0.29 417600.0 -18800.0 -0.11 -0.2847 -0.909 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C17 compound treatment 299300.0 -160000.0 -0.9 226670.0 -210000.0 -1.22 -1.4976 -0.9891 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C18 compound treatment 245600.0 -214000.0 -1.2 190360.0 -246000.0 -1.43 -1.8602 -0.9964 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C19 compound treatment 333160.0 -126000.0 -0.71 216450.0 -220000.0 -1.28 -1.4047 -0.9619 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C20 compound treatment 334650.0 -125000.0 -0.7 234330.0 -202000.0 -1.17 -1.3255 -0.9701 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C21 compound treatment 301780.0 -158000.0 -0.89 257930.0 -178000.0 -1.04 -1.3595 -0.9971 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C22 compound treatment 377640.0 -81800.0 -0.46 377650.0 -58700.0 -0.34 -0.5666 -0.989 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C23 compound treatment 273990.0 -185000.0 -1.04 266450.0 -170000.0 -0.99 -1.4352 -0.9996 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 C24 compound treatment 358300.0 -101000.0 -0.57 257180.0 -179000.0 -1.04 -1.1376 -0.9599 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D01 compound treatment 271270.0 -188000.0 -1.06 219170.0 -217000.0 -1.26 -1.6399 -0.9963 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D02 compound treatment 344000.0 -115000.0 -0.65 255240.0 -181000.0 -1.05 -1.2025 -0.9734 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D03 compound treatment 374140.0 -85300.0 -0.48 249280.0 -187000.0 -1.09 -1.1069 -0.9328 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D04 compound treatment 256680.0 -203000.0 -1.14 309480.0 -127000.0 -0.74 -1.3276 -0.9775 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D05 compound treatment 325690.0 -134000.0 -0.75 321800.0 -115000.0 -0.66 -1.0024 -0.9981 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D06 compound treatment 320900.0 -139000.0 -0.78 238740.0 -198000.0 -1.15 -1.3621 -0.9824 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D07 compound treatment 500960.0 41500.0 0.23 512390.0 76000.0 0.44 0.4768 0.956 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D08 compound treatment 351010.0 -108000.0 -0.61 469760.0 33400.0 0.19 -0.2949 -0.4604 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D09 compound treatment 322850.0 -137000.0 -0.77 349850.0 -86500.0 -0.5 -0.8987 -0.9786 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D10 compound treatment 388120.0 -71300.0 -0.4 425840.0 -10600.0 -0.06 -0.3273 -0.8056 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D11 mock treatment 594250.0 135000.0 0.76 290410.0 -146000.0 -0.85 -0.0621 -0.0546 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D12 mock treatment 487640.0 28200.0 0.16 491130.0 54700.0 0.32 0.3366 0.9487 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D13 compound treatment 263880.0 -196000.0 -1.1 459310.0 22900.0 0.13 -0.6846 -0.6173 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D14 compound treatment 177280.0 -282000.0 -1.59 160430.0 -276000.0 -1.6 -2.2549 -1.0 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D15 mock treatment 481540.0 22100.0 0.12 530910.0 94500.0 0.55 0.4755 0.846 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D16 mock treatment 582140.0 123000.0 0.69 369280.0 -67100.0 -0.39 0.2131 0.2688 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D17 compound treatment 435960.0 -23500.0 -0.13 292800.0 -144000.0 -0.83 -0.6824 -0.8093 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D18 compound treatment 369290.0 -90200.0 -0.51 350640.0 -85800.0 -0.5 -0.7106 -0.9999 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D19 compound treatment 338900.0 -121000.0 -0.68 333560.0 -103000.0 -0.6 -0.9016 -0.9979 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D20 compound treatment 109060.0 -350000.0 -1.97 52410.0 -384000.0 -2.23 -2.9695 -0.9982 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D21 compound treatment 413950.0 -45500.0 -0.26 329970.0 -106000.0 -0.62 -0.6176 -0.9241 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D22 compound treatment 529760.0 70300.0 0.4 476560.0 40200.0 0.23 0.4446 0.968 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D23 compound treatment 419910.0 -39500.0 -0.22 345690.0 -90700.0 -0.53 -0.5294 -0.9268 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 D24 compound treatment 338020.0 -121000.0 -0.68 251720.0 -185000.0 -1.07 -1.2407 -0.9765 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E01 mock treatment 276740.0 -183000.0 -1.03 562600.0 126000.0 0.73 -0.2098 -0.1662 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E02 mock treatment 441850.0 -17600.0 -0.1 278490.0 -158000.0 -0.92 -0.7176 -0.7791 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E03 compound treatment 201390.0 -258000.0 -1.45 191680.0 -245000.0 -1.42 -2.0308 -0.9999 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E04 compound treatment 279940.0 -180000.0 -1.01 143230.0 -293000.0 -1.7 -1.9168 -0.9691 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E05 compound treatment 242430.0 -217000.0 -1.22 178590.0 -258000.0 -1.5 -1.9211 -0.995 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E06 compound treatment 205460.0 -254000.0 -1.43 193370.0 -243000.0 -1.41 -2.0077 -1.0 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E07 compound treatment 258580.0 -201000.0 -1.13 166780.0 -270000.0 -1.56 -1.9053 -0.9873 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E08 compound treatment 215850.0 -244000.0 -1.37 63520.0 -373000.0 -2.16 -2.4988 -0.9758 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E09 mock treatment 379470.0 -80000.0 -0.45 553330.0 117000.0 0.68 0.1611 0.1979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E10 mock treatment 569600.0 110000.0 0.62 585810.0 149000.0 0.87 1.0512 0.9865 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E11 compound treatment 249950.0 -210000.0 -1.18 292910.0 -143000.0 -0.83 -1.4224 -0.9854 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E12 compound treatment 153600.0 -306000.0 -1.72 197280.0 -239000.0 -1.39 -2.1981 -0.9942 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E13 compound treatment 235840.0 -224000.0 -1.26 237510.0 -199000.0 -1.15 -1.7057 -0.999 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E14 compound treatment 322750.0 -137000.0 -0.77 209010.0 -227000.0 -1.32 -1.4767 -0.9671 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E15 compound treatment 375420.0 -84000.0 -0.47 267520.0 -169000.0 -0.98 -1.0271 -0.9443 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E16 compound treatment 502580.0 43100.0 0.24 381440.0 -55000.0 -0.32 -0.0537 -0.134 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E17 mock treatment 553160.0 93700.0 0.53 380050.0 -56300.0 -0.33 0.1419 0.2287 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E18 mock treatment 567360.0 108000.0 0.61 557210.0 121000.0 0.7 0.925 0.9975 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E19 compound treatment 282140.0 -177000.0 -1.0 189440.0 -247000.0 -1.43 -1.7186 -0.9844 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E20 compound treatment 320540.0 -139000.0 -0.78 456690.0 20300.0 0.12 -0.4698 -0.594 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E21 compound treatment 302770.0 -157000.0 -0.88 199450.0 -237000.0 -1.37 -1.5954 -0.977 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E22 compound treatment 314040.0 -145000.0 -0.82 232910.0 -203000.0 -1.18 -1.4133 -0.984 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E23 compound treatment 259490.0 -200000.0 -1.13 236860.0 -200000.0 -1.16 -1.6143 -0.9999 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 E24 compound treatment 224610.0 -235000.0 -1.32 295000.0 -141000.0 -0.82 -1.5147 -0.9736 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F01 mock treatment 508770.0 49300.0 0.28 514880.0 78500.0 0.46 0.5181 0.9719 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F02 mock treatment 186000.0 -273000.0 -1.54 526170.0 89800.0 0.52 -0.7204 -0.4433 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F03 compound treatment 390130.0 -69300.0 -0.39 216390.0 -220000.0 -1.28 -1.1782 -0.883 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F04 compound treatment 191230.0 -268000.0 -1.51 295360.0 -141000.0 -0.82 -1.6461 -0.9585 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F05 compound treatment 226470.0 -233000.0 -1.31 198170.0 -238000.0 -1.38 -1.9044 -0.9997 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F06 compound treatment 143550.0 -316000.0 -1.78 99220.0 -337000.0 -1.96 -2.6402 -0.9989 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F07 compound treatment 194660.0 -265000.0 -1.49 234750.0 -202000.0 -1.17 -1.881 -0.9928 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F08 compound treatment 307130.0 -152000.0 -0.86 261650.0 -175000.0 -1.01 -1.323 -0.9965 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F09 mock treatment 446090.0 -13400.0 -0.08 326600.0 -110000.0 -0.64 -0.5035 -0.7852 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F10 mock treatment 285510.0 -174000.0 -0.98 349340.0 -87100.0 -0.5 -1.0494 -0.9525 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F11 compound treatment 316160.0 -143000.0 -0.81 175220.0 -261000.0 -1.51 -1.6415 -0.9565 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F12 compound treatment 479840.0 20400.0 0.11 189770.0 -247000.0 -1.43 -0.9302 -0.6483 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F13 compound treatment 325940.0 -134000.0 -0.75 214670.0 -222000.0 -1.29 -1.4407 -0.9673 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F14 compound treatment 464920.0 5470.0 0.03 288060.0 -148000.0 -0.86 -0.5866 -0.6814 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F15 compound treatment 552100.0 92600.0 0.52 252640.0 -184000.0 -1.07 -0.3848 -0.3243 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F16 compound treatment 344960.0 -114000.0 -0.64 268860.0 -168000.0 -0.97 -1.1428 -0.9801 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F17 mock treatment 478030.0 18600.0 0.1 386620.0 -49800.0 -0.29 -0.1302 -0.424 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F18 mock treatment 519840.0 60400.0 0.34 385460.0 -50900.0 -0.3 0.0315 0.0699 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F19 compound treatment 259590.0 -200000.0 -1.13 345990.0 -90400.0 -0.52 -1.1663 -0.9396 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F20 compound treatment 345280.0 -114000.0 -0.64 437560.0 1160.0 0.01 -0.4497 -0.6997 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F21 compound treatment 238940.0 -221000.0 -1.24 344980.0 -91400.0 -0.53 -1.2527 -0.928 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F22 compound treatment 211250.0 -248000.0 -1.4 173550.0 -263000.0 -1.52 -2.0659 -0.9991 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F23 compound treatment 286480.0 -173000.0 -0.97 284220.0 -152000.0 -0.88 -1.3126 -0.9988 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 F24 compound treatment 378330.0 -81100.0 -0.46 309860.0 -127000.0 -0.73 -0.8418 -0.974 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G01 compound treatment 283370.0 -176000.0 -0.99 201600.0 -235000.0 -1.36 -1.6638 -0.9878 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G02 compound treatment 256000.0 -203000.0 -1.15 299150.0 -137000.0 -0.8 -1.3727 -0.9842 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G03 mock treatment 588270.0 129000.0 0.73 370630.0 -65800.0 -0.38 0.2431 0.2967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G04 mock treatment 209120.0 -250000.0 -1.41 270560.0 -166000.0 -0.96 -1.6766 -0.9827 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G05 compound treatment 204090.0 -255000.0 -1.44 223760.0 -213000.0 -1.23 -1.8885 -0.9971 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G06 compound treatment 124030.0 -335000.0 -1.89 186560.0 -250000.0 -1.45 -2.3598 -0.9914 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G07 compound treatment 315360.0 -144000.0 -0.81 233300.0 -203000.0 -1.18 -1.4065 -0.9834 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G08 compound treatment 191770.0 -268000.0 -1.51 193790.0 -243000.0 -1.41 -2.0605 -0.9994 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G09 compound treatment 254240.0 -205000.0 -1.16 104960.0 -331000.0 -1.92 -2.1761 -0.9703 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G10 compound treatment 234190.0 -225000.0 -1.27 241790.0 -195000.0 -1.13 -1.6948 -0.9983 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G11 compound treatment 155600.0 -304000.0 -1.71 156220.0 -280000.0 -1.62 -2.3585 -0.9997 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G12 compound treatment 441040.0 -18400.0 -0.1 248120.0 -188000.0 -1.09 -0.8454 -0.7708 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G13 compound treatment 156230.0 -303000.0 -1.71 188960.0 -247000.0 -1.43 -2.2217 -0.9963 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G14 compound treatment 133000.0 -326000.0 -1.84 84220.0 -352000.0 -2.04 -2.7437 -0.9986 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G15 compound treatment 199680.0 -260000.0 -1.46 155740.0 -281000.0 -1.63 -2.185 -0.9986 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G16 compound treatment 215040.0 -244000.0 -1.38 213650.0 -223000.0 -1.29 -1.8864 -0.9995 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G17 compound treatment 131630.0 -328000.0 -1.85 147010.0 -289000.0 -1.68 -2.4917 -0.9989 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G18 compound treatment 283530.0 -176000.0 -0.99 316650.0 -120000.0 -0.69 -1.1914 -0.9849 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G19 mock treatment 406030.0 -53400.0 -0.3 477030.0 40600.0 0.24 -0.046 -0.1205 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G20 mock treatment 365720.0 -93700.0 -0.53 354980.0 -81400.0 -0.47 -0.707 -0.9985 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G21 compound treatment 245990.0 -213000.0 -1.2 272160.0 -164000.0 -0.95 -1.5232 -0.9934 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G22 compound treatment 238560.0 -221000.0 -1.24 210820.0 -226000.0 -1.31 -1.8044 -0.9997 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G23 compound treatment 304370.0 -155000.0 -0.87 297920.0 -138000.0 -0.8 -1.1852 -0.9991 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 G24 compound treatment 325690.0 -134000.0 -0.75 240960.0 -195000.0 -1.13 -1.3339 -0.9803 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H01 compound treatment 218580.0 -241000.0 -1.36 219010.0 -217000.0 -1.26 -1.8503 -0.9993 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H02 compound treatment 276800.0 -183000.0 -1.03 292030.0 -144000.0 -0.84 -1.3191 -0.9948 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H03 mock treatment 521980.0 62500.0 0.35 237460.0 -199000.0 -1.15 -0.5669 -0.47 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H04 mock treatment 261530.0 -198000.0 -1.11 559910.0 124000.0 0.72 -0.2814 -0.2124 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H05 compound treatment 492640.0 33200.0 0.19 179330.0 -257000.0 -1.49 -0.9221 -0.6137 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H06 compound treatment 515860.0 56400.0 0.32 420410.0 -16000.0 -0.09 0.159 0.4806 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H07 compound treatment 454250.0 -5210.0 -0.03 220920.0 -215000.0 -1.25 -0.9044 -0.7235 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H08 compound treatment 168000.0 -291000.0 -1.64 163950.0 -272000.0 -1.58 -2.2774 -0.9998 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H09 compound treatment 255680.0 -204000.0 -1.15 252100.0 -184000.0 -1.07 -1.5669 -0.9994 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H10 compound treatment 89850.0 -370000.0 -2.08 91380.0 -345000.0 -2.0 -2.8861 -0.9998 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H11 compound treatment 153970.0 -305000.0 -1.72 207290.0 -229000.0 -1.33 -2.1556 -0.9919 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H12 compound treatment 171810.0 -288000.0 -1.62 185170.0 -251000.0 -1.46 -2.1753 -0.9986 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H13 compound treatment 263650.0 -196000.0 -1.1 361050.0 -75300.0 -0.44 -1.0884 -0.9179 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H14 compound treatment 13600.0 -446000.0 -2.51 14660.0 -422000.0 -2.45 -3.5043 -0.9999 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H15 compound treatment 210200.0 -249000.0 -1.4 325460.0 -111000.0 -0.64 -1.4471 -0.9375 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H16 compound treatment 390110.0 -69300.0 -0.39 219230.0 -217000.0 -1.26 -1.1666 -0.8848 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H17 compound treatment 329390.0 -130000.0 -0.73 360680.0 -75700.0 -0.44 -0.8283 -0.9701 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H18 compound treatment 21090.0 -438000.0 -2.47 16750.0 -420000.0 -2.43 -3.4659 -1.0 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H19 mock treatment 378730.0 -80700.0 -0.45 528850.0 92500.0 0.54 0.0578 0.0822 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H20 mock treatment 448480.0 -11000.0 -0.06 549690.0 113000.0 0.66 0.4209 0.6378 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H21 compound treatment 256040.0 -203000.0 -1.15 298030.0 -138000.0 -0.8 -1.3772 -0.9849 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H22 compound treatment 281130.0 -178000.0 -1.0 126620.0 -310000.0 -1.8 -1.9802 -0.9622 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H23 compound treatment 430030.0 -29400.0 -0.17 326170.0 -110000.0 -0.64 -0.5692 -0.8619 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 H24 compound treatment 417290.0 -42200.0 -0.24 392490.0 -43900.0 -0.25 -0.3479 -0.9994 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I01 compound treatment 202940.0 -257000.0 -1.44 259560.0 -177000.0 -1.03 -1.7463 -0.9859 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I02 compound treatment 229930.0 -230000.0 -1.29 332100.0 -104000.0 -0.6 -1.3414 -0.9402 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I03 compound treatment 390650.0 -68800.0 -0.39 214530.0 -222000.0 -1.29 -1.1837 -0.8809 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I04 compound treatment 100980.0 -358000.0 -2.02 95910.0 -340000.0 -1.97 -2.8233 -0.9999 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I05 mock treatment 526020.0 66600.0 0.37 454800.0 18400.0 0.11 0.3404 0.8737 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I06 mock treatment 480830.0 21400.0 0.12 344480.0 -91900.0 -0.53 -0.2919 -0.5341 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I07 compound treatment 198330.0 -261000.0 -1.47 301560.0 -135000.0 -0.78 -1.5924 -0.9564 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I08 compound treatment 140610.0 -319000.0 -1.79 457380.0 21000.0 0.12 -1.1832 -0.6577 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I09 compound treatment 403260.0 -56200.0 -0.32 585600.0 149000.0 0.87 0.3882 0.4213 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I10 compound treatment 194040.0 -265000.0 -1.49 116850.0 -320000.0 -1.85 -2.3669 -0.9943 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I11 compound treatment 174300.0 -285000.0 -1.61 148880.0 -288000.0 -1.67 -2.3142 -0.9998 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I12 compound treatment 195840.0 -264000.0 -1.48 197620.0 -239000.0 -1.38 -2.0286 -0.9994 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I13 compound treatment 409530.0 -49900.0 -0.28 319880.0 -117000.0 -0.68 -0.6766 -0.9244 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I14 compound treatment 287940.0 -172000.0 -0.97 317680.0 -119000.0 -0.69 -1.1696 -0.9863 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I15 compound treatment 331800.0 -128000.0 -0.72 356960.0 -79400.0 -0.46 -0.8339 -0.9769 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I16 compound treatment 217530.0 -242000.0 -1.36 136450.0 -300000.0 -1.74 -2.1931 -0.9927 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I17 compound treatment 325600.0 -134000.0 -0.75 188820.0 -248000.0 -1.44 -1.5481 -0.9547 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I18 compound treatment 287520.0 -172000.0 -0.97 432050.0 -4350.0 -0.03 -0.7022 -0.7253 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I19 compound treatment 375080.0 -84400.0 -0.47 360980.0 -75400.0 -0.44 -0.6451 -0.9992 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I20 compound treatment 345230.0 -114000.0 -0.64 276280.0 -160000.0 -0.93 -1.1113 -0.9839 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I21 mock treatment 547420.0 88000.0 0.5 371290.0 -65100.0 -0.38 0.0832 0.1335 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I22 mock treatment 381850.0 -77600.0 -0.44 352610.0 -83800.0 -0.49 -0.6525 -0.9986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I23 compound treatment 392400.0 -67100.0 -0.38 256980.0 -179000.0 -1.04 -1.0027 -0.9059 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 I24 compound treatment 358470.0 -101000.0 -0.57 289470.0 -147000.0 -0.85 -1.0045 -0.9806 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J01 compound treatment 397280.0 -62200.0 -0.35 190570.0 -246000.0 -1.43 -1.2556 -0.8553 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J02 compound treatment 246170.0 -213000.0 -1.2 469120.0 32700.0 0.19 -0.7148 -0.5881 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J03 compound treatment 203910.0 -256000.0 -1.44 226740.0 -210000.0 -1.22 -1.877 -0.9965 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J04 compound treatment 327130.0 -132000.0 -0.74 405720.0 -30700.0 -0.18 -0.6525 -0.852 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J05 mock treatment 201350.0 -258000.0 -1.45 278740.0 -158000.0 -0.91 -1.674 -0.9751 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J06 mock treatment 407380.0 -52100.0 -0.29 454890.0 18500.0 0.11 -0.1315 -0.4211 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J07 compound treatment 439840.0 -19600.0 -0.11 447910.0 11500.0 0.07 -0.0309 -0.2393 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J08 compound treatment 15540.0 -444000.0 -2.5 22560.0 -414000.0 -2.4 -3.4642 -0.9998 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J09 compound treatment 306680.0 -153000.0 -0.86 265300.0 -171000.0 -0.99 -1.3098 -0.9975 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J10 compound treatment 328740.0 -131000.0 -0.74 334330.0 -102000.0 -0.59 -0.9389 -0.9942 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J11 compound treatment 211360.0 -248000.0 -1.4 378690.0 -57700.0 -0.33 -1.2242 -0.8524 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J12 compound treatment 74490.0 -385000.0 -2.17 136490.0 -300000.0 -1.74 -2.7623 -0.9941 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J13 compound treatment 178080.0 -281000.0 -1.58 255310.0 -181000.0 -1.05 -1.8627 -0.9801 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J14 compound treatment 461730.0 2280.0 0.01 395380.0 -41000.0 -0.24 -0.1592 -0.6681 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J15 compound treatment 304900.0 -155000.0 -0.87 303810.0 -133000.0 -0.77 -1.159 -0.9981 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J16 compound treatment 394970.0 -64500.0 -0.36 405320.0 -31100.0 -0.18 -0.3841 -0.9478 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J17 compound treatment 395430.0 -64000.0 -0.36 346980.0 -89400.0 -0.52 -0.6216 -0.9842 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J18 compound treatment 221600.0 -238000.0 -1.34 290400.0 -146000.0 -0.85 -1.5455 -0.9756 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J19 compound treatment 445440.0 -14000.0 -0.08 498430.0 62000.0 0.36 0.1986 0.5392 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J20 compound treatment 301410.0 -158000.0 -0.89 300340.0 -136000.0 -0.79 -1.1871 -0.9982 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J21 mock treatment 387000.0 -72500.0 -0.41 286980.0 -149000.0 -0.87 -0.9012 -0.9409 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J22 mock treatment 368320.0 -91100.0 -0.51 330880.0 -106000.0 -0.61 -0.7955 -0.9962 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J23 compound treatment 426950.0 -32500.0 -0.18 293400.0 -143000.0 -0.83 -0.7158 -0.8429 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 J24 compound treatment 306950.0 -153000.0 -0.86 353410.0 -83000.0 -0.48 -0.9474 -0.9626 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K01 compound treatment 459880.0 425.0 0.0 481530.0 45100.0 0.26 0.1868 0.7135 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K02 compound treatment 135740.0 -324000.0 -1.82 245440.0 -191000.0 -1.11 -2.0717 -0.9715 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K03 compound treatment 448680.0 -10800.0 -0.06 338560.0 -97800.0 -0.57 -0.4441 -0.7783 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K04 compound treatment 242400.0 -217000.0 -1.22 201000.0 -235000.0 -1.37 -1.8293 -0.9985 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K05 compound treatment 287310.0 -172000.0 -0.97 328390.0 -108000.0 -0.63 -1.1282 -0.9777 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K06 compound treatment 46330.0 -413000.0 -2.33 117000.0 -319000.0 -1.85 -2.9543 -0.9936 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K07 mock treatment 178500.0 -281000.0 -1.58 436450.0 51.4 0.0 -1.1182 -0.707 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K08 mock treatment 485210.0 25800.0 0.14 381630.0 -54800.0 -0.32 -0.1221 -0.3496 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K09 compound treatment 458950.0 -505.0 0.0 294970.0 -141000.0 -0.82 -0.582 -0.7096 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K10 compound treatment 226080.0 -233000.0 -1.31 204760.0 -232000.0 -1.34 -1.8789 -0.9999 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K11 compound treatment 308440.0 -151000.0 -0.85 262350.0 -174000.0 -1.01 -1.3149 -0.9964 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K12 compound treatment 240260.0 -219000.0 -1.23 195840.0 -241000.0 -1.4 -1.859 -0.9981 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K13 compound treatment 352890.0 -107000.0 -0.6 284320.0 -152000.0 -0.88 -1.0478 -0.9824 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K14 compound treatment 233890.0 -226000.0 -1.27 265650.0 -171000.0 -0.99 -1.5981 -0.9924 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K15 mock treatment 443490.0 -16000.0 -0.09 488890.0 52500.0 0.3 0.1517 0.4779 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K16 mock treatment 607710.0 148000.0 0.83 471370.0 35000.0 0.2 0.7336 0.8541 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K17 compound treatment 237520.0 -222000.0 -1.25 266610.0 -170000.0 -0.98 -1.5797 -0.9931 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K18 compound treatment 224490.0 -235000.0 -1.32 236700.0 -200000.0 -1.16 -1.7542 -0.9978 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K19 compound treatment 596670.0 137000.0 0.77 397920.0 -38500.0 -0.22 0.3884 0.4831 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K20 compound treatment 306980.0 -152000.0 -0.86 237830.0 -199000.0 -1.15 -1.4212 -0.9895 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K21 compound treatment 405350.0 -54100.0 -0.3 297160.0 -139000.0 -0.81 -0.7864 -0.9112 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K22 compound treatment 295950.0 -164000.0 -0.92 396610.0 -39800.0 -0.23 -0.814 -0.8578 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K23 mock treatment 372800.0 -86700.0 -0.49 405700.0 -30700.0 -0.18 -0.4708 -0.9067 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 K24 mock treatment 430250.0 -29200.0 -0.16 333790.0 -103000.0 -0.6 -0.537 -0.8699 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L01 compound treatment 296420.0 -163000.0 -0.92 347320.0 -89100.0 -0.52 -1.0143 -0.963 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L02 compound treatment 380580.0 -78900.0 -0.44 314850.0 -122000.0 -0.7 -0.8124 -0.9752 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L03 compound treatment 152820.0 -307000.0 -1.73 233630.0 -203000.0 -1.18 -2.0521 -0.9825 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L04 compound treatment 199150.0 -260000.0 -1.47 309880.0 -127000.0 -0.73 -1.555 -0.9489 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L05 compound treatment 463470.0 4020.0 0.02 200920.0 -235000.0 -1.37 -0.9497 -0.6953 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L06 compound treatment 470420.0 11000.0 0.06 191560.0 -245000.0 -1.42 -0.9604 -0.6757 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L07 mock treatment 467040.0 7590.0 0.04 443650.0 7250.0 0.04 0.0599 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L08 mock treatment 471410.0 12000.0 0.07 437540.0 1140.0 0.01 0.0523 0.7729 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L09 compound treatment 132430.0 -327000.0 -1.84 399690.0 -36700.0 -0.21 -1.4523 -0.7837 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L10 compound treatment 428820.0 -30600.0 -0.17 417210.0 -19200.0 -0.11 -0.2006 -0.9775 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L11 compound treatment 432380.0 -27100.0 -0.15 187210.0 -249000.0 -1.45 -1.1297 -0.7774 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L12 compound treatment 401050.0 -58400.0 -0.33 473760.0 37400.0 0.22 -0.0793 -0.2013 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L13 compound treatment 242250.0 -217000.0 -1.22 361880.0 -74500.0 -0.43 -1.1702 -0.9023 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L14 compound treatment 324890.0 -135000.0 -0.76 309520.0 -127000.0 -0.74 -1.056 -0.9999 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L15 mock treatment 351170.0 -108000.0 -0.61 618040.0 182000.0 1.05 0.3138 0.2579 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L16 mock treatment 428110.0 -31300.0 -0.18 462240.0 25800.0 0.15 -0.0188 -0.0812 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L17 compound treatment 578170.0 119000.0 0.67 323280.0 -113000.0 -0.66 0.0087 0.0093 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L18 compound treatment 564850.0 105000.0 0.59 437470.0 1070.0 0.01 0.4239 0.7145 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L19 compound treatment 186730.0 -273000.0 -1.54 294250.0 -142000.0 -0.82 -1.6686 -0.9575 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L20 compound treatment 501530.0 42100.0 0.24 315100.0 -121000.0 -0.7 -0.3299 -0.4445 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L21 compound treatment 317850.0 -142000.0 -0.8 286620.0 -150000.0 -0.87 -1.1779 -0.9991 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L22 compound treatment 404210.0 -55200.0 -0.31 408430.0 -28000.0 -0.16 -0.3346 -0.9539 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L23 mock treatment 471590.0 12100.0 0.07 513540.0 77100.0 0.45 0.3646 0.8057 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 L24 mock treatment 474010.0 14600.0 0.08 478530.0 42100.0 0.24 0.2307 0.8952 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M01 compound treatment 131780.0 -328000.0 -1.84 145440.0 -291000.0 -1.69 -2.4975 -0.999 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M02 compound treatment 134530.0 -325000.0 -1.83 112890.0 -324000.0 -1.88 -2.6201 -0.9999 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M03 compound treatment 223450.0 -236000.0 -1.33 215200.0 -221000.0 -1.28 -1.8466 -0.9998 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M04 compound treatment 214520.0 -245000.0 -1.38 281530.0 -155000.0 -0.9 -1.6101 -0.9784 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M05 compound treatment 119160.0 -340000.0 -1.92 189840.0 -247000.0 -1.43 -2.3657 -0.9896 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M06 compound treatment 173440.0 -286000.0 -1.61 212210.0 -224000.0 -1.3 -2.0579 -0.9944 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M07 compound treatment 189880.0 -270000.0 -1.52 314930.0 -121000.0 -0.7 -1.5712 -0.9391 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M08 compound treatment 143040.0 -316000.0 -1.78 138040.0 -298000.0 -1.73 -2.4831 -0.9999 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M09 mock treatment 418830.0 -40600.0 -0.23 583050.0 147000.0 0.85 0.4397 0.4992 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M10 mock treatment 470280.0 10800.0 0.06 612160.0 176000.0 1.02 0.7639 0.748 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M11 compound treatment 357080.0 -102000.0 -0.58 417600.0 -18800.0 -0.11 -0.4846 -0.8262 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M12 compound treatment 332990.0 -126000.0 -0.71 550480.0 114000.0 0.66 -0.0356 -0.0366 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M13 mock treatment 522290.0 62800.0 0.35 620840.0 184000.0 1.07 1.0065 0.8934 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M14 mock treatment 404480.0 -55000.0 -0.31 554400.0 118000.0 0.68 0.2651 0.3529 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M15 compound treatment 246510.0 -213000.0 -1.2 237290.0 -199000.0 -1.15 -1.6642 -0.9998 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M16 compound treatment 283330.0 -176000.0 -0.99 381010.0 -55400.0 -0.32 -0.9282 -0.8906 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M17 compound treatment 114640.0 -345000.0 -1.94 226890.0 -210000.0 -1.22 -2.2318 -0.9745 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M18 compound treatment 249440.0 -210000.0 -1.18 270900.0 -165000.0 -0.96 -1.5147 -0.9946 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M19 compound treatment 486880.0 27400.0 0.15 571360.0 135000.0 0.78 0.6626 0.8306 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M20 compound treatment 114450.0 -345000.0 -1.94 318650.0 -118000.0 -0.68 -1.8562 -0.9016 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M21 compound treatment 296850.0 -163000.0 -0.92 294180.0 -142000.0 -0.82 -1.2305 -0.9986 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M22 compound treatment 341690.0 -118000.0 -0.66 353630.0 -82800.0 -0.48 -0.8082 -0.9874 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M23 compound treatment 349480.0 -110000.0 -0.62 394400.0 -42000.0 -0.24 -0.61 -0.9169 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 M24 compound treatment 234920.0 -225000.0 -1.26 183160.0 -253000.0 -1.47 -1.9323 -0.9972 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N01 compound treatment 324610.0 -135000.0 -0.76 293770.0 -143000.0 -0.83 -1.1217 -0.9991 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N02 compound treatment 440000.0 -19500.0 -0.11 459400.0 23000.0 0.13 0.0169 0.0978 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N03 compound treatment 368860.0 -90600.0 -0.51 255710.0 -181000.0 -1.05 -1.1016 -0.9452 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N04 compound treatment 219530.0 -240000.0 -1.35 213160.0 -223000.0 -1.29 -1.8705 -0.9998 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N05 compound treatment 178560.0 -281000.0 -1.58 443430.0 7030.0 0.04 -1.0893 -0.6886 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N06 compound treatment 360920.0 -98500.0 -0.55 370010.0 -66400.0 -0.39 -0.6645 -0.9841 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N07 compound treatment 417120.0 -42300.0 -0.24 364480.0 -71900.0 -0.42 -0.4634 -0.9648 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N08 compound treatment 333010.0 -126000.0 -0.71 509780.0 73400.0 0.43 -0.2024 -0.2441 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N09 mock treatment 530830.0 71400.0 0.4 522630.0 86200.0 0.5 0.6377 0.9941 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N10 mock treatment 506400.0 46900.0 0.26 568730.0 132000.0 0.77 0.7295 0.8988 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N11 compound treatment 311010.0 -148000.0 -0.84 167000.0 -269000.0 -1.56 -1.6957 -0.957 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N12 compound treatment 309440.0 -150000.0 -0.84 207280.0 -229000.0 -1.33 -1.5367 -0.9761 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N13 mock treatment 584260.0 125000.0 0.7 553410.0 117000.0 0.68 0.9766 0.9998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N14 mock treatment 554050.0 94600.0 0.53 519970.0 83600.0 0.48 0.7193 0.9989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N15 compound treatment 207890.0 -252000.0 -1.42 317820.0 -119000.0 -0.69 -1.4877 -0.945 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N16 compound treatment 417280.0 -42200.0 -0.24 437460.0 1060.0 0.01 -0.1635 -0.6885 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N17 compound treatment 525280.0 65800.0 0.37 330770.0 -106000.0 -0.61 -0.1711 -0.239 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N18 compound treatment 423330.0 -36100.0 -0.2 511730.0 75300.0 0.44 0.1651 0.3426 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N19 compound treatment 309800.0 -150000.0 -0.84 451480.0 15100.0 0.09 -0.5339 -0.6303 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N20 compound treatment 544840.0 85400.0 0.48 397400.0 -39000.0 -0.23 0.18 0.3388 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N21 compound treatment 221950.0 -238000.0 -1.34 205050.0 -231000.0 -1.34 -1.8941 -1.0 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N22 compound treatment 209320.0 -250000.0 -1.41 149380.0 -287000.0 -1.66 -2.1727 -0.9965 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N23 compound treatment 271950.0 -188000.0 -1.06 329220.0 -107000.0 -0.62 -1.1859 -0.9681 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 N24 compound treatment 482260.0 22800.0 0.13 315800.0 -121000.0 -0.7 -0.4038 -0.5678 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O01 compound treatment 492520.0 33100.0 0.19 389240.0 -47200.0 -0.27 -0.0618 -0.1867 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O02 compound treatment 227690.0 -232000.0 -1.3 231010.0 -205000.0 -1.19 -1.7648 -0.999 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O03 compound treatment 260660.0 -199000.0 -1.12 506820.0 70400.0 0.41 -0.5026 -0.4218 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O04 compound treatment 168050.0 -291000.0 -1.64 163040.0 -273000.0 -1.59 -2.281 -0.9999 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O05 compound treatment 200380.0 -259000.0 -1.46 229030.0 -207000.0 -1.2 -1.8817 -0.9954 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O06 compound treatment 18140.0 -441000.0 -2.48 204160.0 -232000.0 -1.35 -2.7091 -0.9586 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O07 compound treatment 317980.0 -141000.0 -0.8 205920.0 -230000.0 -1.34 -1.5083 -0.9694 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O08 compound treatment 216160.0 -243000.0 -1.37 200100.0 -236000.0 -1.37 -1.9375 -1.0 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O09 compound treatment 196920.0 -263000.0 -1.48 150660.0 -286000.0 -1.66 -2.2168 -0.9984 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O10 compound treatment 254970.0 -204000.0 -1.15 238580.0 -198000.0 -1.15 -1.6252 -1.0 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O11 mock treatment 474450.0 15000.0 0.08 505020.0 68600.0 0.4 0.3411 0.8384 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O12 mock treatment 575090.0 116000.0 0.65 311520.0 -125000.0 -0.72 -0.0518 -0.0532 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O13 compound treatment 195780.0 -264000.0 -1.48 261920.0 -174000.0 -1.01 -1.7651 -0.9826 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O14 compound treatment 280800.0 -179000.0 -1.01 209650.0 -227000.0 -1.32 -1.641 -0.9912 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O15 compound treatment 182490.0 -277000.0 -1.56 158510.0 -278000.0 -1.61 -2.2421 -0.9999 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O16 compound treatment 243200.0 -216000.0 -1.22 207590.0 -229000.0 -1.33 -1.7991 -0.9991 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O17 compound treatment 239110.0 -220000.0 -1.24 368160.0 -68200.0 -0.4 -1.157 -0.8886 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O18 compound treatment 228570.0 -231000.0 -1.3 245560.0 -191000.0 -1.11 -1.7017 -0.9968 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O19 compound treatment 263260.0 -196000.0 -1.1 237340.0 -199000.0 -1.15 -1.5973 -0.9998 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O20 compound treatment 185640.0 -274000.0 -1.54 211130.0 -225000.0 -1.31 -2.0138 -0.9966 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O21 compound treatment 245380.0 -214000.0 -1.21 188210.0 -248000.0 -1.44 -1.8699 -0.9961 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O22 compound treatment 254930.0 -205000.0 -1.15 201400.0 -235000.0 -1.36 -1.7778 -0.9965 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O23 compound treatment 299800.0 -160000.0 -0.9 299360.0 -137000.0 -0.79 -1.1975 -0.9981 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 O24 compound treatment 175770.0 -284000.0 -1.6 216480.0 -220000.0 -1.28 -2.0311 -0.9938 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P01 compound treatment 86660.0 -373000.0 -2.1 98960.0 -337000.0 -1.96 -2.8677 -0.9994 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P02 compound treatment 186500.0 -273000.0 -1.54 368570.0 -67800.0 -0.39 -1.3647 -0.8604 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P03 compound treatment 169690.0 -290000.0 -1.63 192730.0 -244000.0 -1.41 -2.1527 -0.9974 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P04 compound treatment 238620.0 -221000.0 -1.24 150200.0 -286000.0 -1.66 -2.0527 -0.9899 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P05 compound treatment 74640.0 -385000.0 -2.17 58360.0 -378000.0 -2.19 -3.0821 -1.0 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P06 compound treatment 437990.0 -21500.0 -0.12 433410.0 -2990.0 -0.02 -0.0977 -0.8003 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P07 compound treatment 305660.0 -154000.0 -0.87 287300.0 -149000.0 -0.86 -1.2236 -1.0 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P08 compound treatment 338430.0 -121000.0 -0.68 412060.0 -24300.0 -0.14 -0.5816 -0.8359 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P09 compound treatment 180860.0 -279000.0 -1.57 171040.0 -265000.0 -1.54 -2.1972 -1.0 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P10 compound treatment 207010.0 -252000.0 -1.42 287840.0 -149000.0 -0.86 -1.6141 -0.9712 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P11 mock treatment 349090.0 -110000.0 -0.62 227610.0 -209000.0 -1.21 -1.2955 -0.9519 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P12 mock treatment 214640.0 -245000.0 -1.38 293540.0 -143000.0 -0.83 -1.5604 -0.9703 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P13 compound treatment 273230.0 -186000.0 -1.05 136200.0 -300000.0 -1.74 -1.9724 -0.9705 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P14 compound treatment 299600.0 -160000.0 -0.9 326640.0 -110000.0 -0.64 -1.0864 -0.9856 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P15 compound treatment 275680.0 -184000.0 -1.03 235360.0 -201000.0 -1.17 -1.556 -0.9982 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P16 compound treatment 360990.0 -98500.0 -0.55 262840.0 -174000.0 -1.01 -1.1037 -0.9605 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P17 compound treatment 244390.0 -215000.0 -1.21 239400.0 -197000.0 -1.14 -1.664 -0.9996 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P18 compound treatment 218750.0 -241000.0 -1.36 277760.0 -159000.0 -0.92 -1.6087 -0.9822 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P19 compound treatment 186200.0 -273000.0 -1.54 365810.0 -70600.0 -0.41 -1.3772 -0.8652 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P20 compound treatment 214900.0 -245000.0 -1.38 254350.0 -182000.0 -1.06 -1.72 -0.9914 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P21 compound treatment 149250.0 -310000.0 -1.75 188290.0 -248000.0 -1.44 -2.2523 -0.9954 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P22 compound treatment 202750.0 -257000.0 -1.45 276490.0 -160000.0 -0.93 -1.6776 -0.977 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P23 compound treatment 270080.0 -189000.0 -1.07 286510.0 -150000.0 -0.87 -1.3685 -0.9949 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2102 P24 compound treatment 261890.0 -198000.0 -1.11 272050.0 -164000.0 -0.95 -1.4604 -0.997 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A01 compound treatment 379360.0 -30800.0 -0.17 176000.0 -242000.0 -1.4 -1.1148 -0.7885 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A02 compound treatment 276840.0 -133000.0 -0.75 345140.0 -72800.0 -0.42 -0.8292 -0.963 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A03 compound treatment 283950.0 -126000.0 -0.71 326880.0 -91100.0 -0.53 -0.8758 -0.9893 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A04 compound treatment 516580.0 106000.0 0.6 508640.0 90700.0 0.53 0.7956 0.9979 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A05 compound treatment 476730.0 66600.0 0.37 299800.0 -118000.0 -0.69 -0.2195 -0.2811 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A06 compound treatment 195000.0 -215000.0 -1.21 400430.0 -17500.0 -0.1 -0.9283 -0.7637 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A07 compound treatment 261850.0 -148000.0 -0.83 282900.0 -135000.0 -0.78 -1.1442 -0.9995 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A08 compound treatment 307680.0 -102000.0 -0.58 296640.0 -121000.0 -0.7 -0.9054 -0.9952 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A09 compound treatment 255590.0 -155000.0 -0.87 314890.0 -103000.0 -0.6 -1.0379 -0.9832 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A10 compound treatment 317770.0 -92400.0 -0.52 232360.0 -186000.0 -1.08 -1.1288 -0.9443 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A11 compound treatment 299760.0 -110000.0 -0.62 209620.0 -208000.0 -1.21 -1.2938 -0.9523 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A12 compound treatment 252600.0 -158000.0 -0.89 403240.0 -14700.0 -0.09 -0.6875 -0.7715 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A13 mock treatment 523200.0 113000.0 0.64 465570.0 47600.0 0.28 0.6453 0.9302 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A14 mock treatment 303760.0 -106000.0 -0.6 368380.0 -49600.0 -0.29 -0.6268 -0.9434 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A15 compound treatment 245920.0 -164000.0 -0.92 237570.0 -180000.0 -1.05 -1.3935 -0.9981 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A16 compound treatment 321030.0 -89100.0 -0.5 340770.0 -77200.0 -0.45 -0.6713 -0.9984 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A17 compound treatment 490350.0 80200.0 0.45 259750.0 -158000.0 -0.92 -0.3295 -0.3223 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A18 compound treatment 304520.0 -106000.0 -0.59 246090.0 -172000.0 -1.0 -1.1252 -0.9696 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A19 compound treatment 230050.0 -180000.0 -1.01 192480.0 -225000.0 -1.31 -1.6415 -0.9921 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A20 compound treatment 397770.0 -12400.0 -0.07 293700.0 -124000.0 -0.72 -0.5588 -0.772 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A21 compound treatment 184170.0 -226000.0 -1.27 252000.0 -166000.0 -0.96 -1.5801 -0.9905 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A22 compound treatment 297840.0 -112000.0 -0.63 207900.0 -210000.0 -1.22 -1.3084 -0.9534 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A23 compound treatment 341920.0 -68200.0 -0.38 298750.0 -119000.0 -0.69 -0.7604 -0.9616 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 A24 compound treatment 231290.0 -179000.0 -1.01 424700.0 6770.0 0.04 -0.6843 -0.679 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B01 compound treatment 478720.0 68600.0 0.39 462440.0 44500.0 0.26 0.4554 0.9809 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B02 compound treatment 415600.0 5430.0 0.03 324640.0 -93300.0 -0.54 -0.361 -0.6661 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B03 compound treatment 496760.0 86600.0 0.49 560900.0 143000.0 0.83 0.931 0.9679 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B04 compound treatment 534210.0 124000.0 0.7 597880.0 180000.0 1.04 1.2317 0.9809 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B05 compound treatment 462500.0 52300.0 0.29 510200.0 92300.0 0.54 0.5867 0.9605 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B06 compound treatment 312430.0 -97700.0 -0.55 459110.0 41200.0 0.24 -0.2202 -0.3671 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B07 compound treatment 449280.0 39100.0 0.22 442080.0 24100.0 0.14 0.2547 0.9761 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B08 compound treatment 438440.0 28300.0 0.16 481440.0 63500.0 0.37 0.373 0.9296 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B09 compound treatment 535970.0 126000.0 0.71 523840.0 106000.0 0.61 0.9351 0.9975 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B10 compound treatment 325080.0 -85100.0 -0.48 363810.0 -54100.0 -0.31 -0.5607 -0.979 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B11 compound treatment 536560.0 126000.0 0.71 559040.0 141000.0 0.82 1.0818 0.9976 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B12 compound treatment 426170.0 16000.0 0.09 282690.0 -135000.0 -0.78 -0.4909 -0.6218 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B13 mock treatment 333600.0 -76600.0 -0.43 342670.0 -75300.0 -0.44 -0.6134 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B14 mock treatment 568800.0 159000.0 0.89 340450.0 -77500.0 -0.45 0.3137 0.3138 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B15 compound treatment 514900.0 105000.0 0.59 479200.0 61300.0 0.36 0.6681 0.9706 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B16 compound treatment 493810.0 83600.0 0.47 375240.0 -42700.0 -0.25 0.1579 0.2968 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B17 compound treatment 328080.0 -82100.0 -0.46 517370.0 99400.0 0.58 0.081 0.1096 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B18 compound treatment 358100.0 -52100.0 -0.29 297830.0 -120000.0 -0.7 -0.6998 -0.926 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B19 compound treatment 376480.0 -33700.0 -0.19 439890.0 22000.0 0.13 -0.0441 -0.1929 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B20 compound treatment 524280.0 114000.0 0.64 337790.0 -80100.0 -0.46 0.1256 0.1584 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B21 compound treatment 241280.0 -169000.0 -0.95 514560.0 96600.0 0.56 -0.276 -0.2501 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B22 compound treatment 433640.0 23500.0 0.13 236190.0 -182000.0 -1.05 -0.6519 -0.6137 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B23 compound treatment 366180.0 -44000.0 -0.25 411390.0 -6540.0 -0.04 -0.2019 -0.8061 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 B24 compound treatment 302940.0 -107000.0 -0.6 390850.0 -27100.0 -0.16 -0.5379 -0.8624 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C01 compound treatment 389440.0 -20700.0 -0.12 265470.0 -152000.0 -0.88 -0.7077 -0.7935 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C02 compound treatment 419360.0 9190.0 0.05 393020.0 -24900.0 -0.14 -0.0656 -0.4273 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C03 compound treatment 456640.0 46500.0 0.26 346800.0 -71100.0 -0.41 -0.1067 -0.2185 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C04 compound treatment 438880.0 28700.0 0.16 456850.0 38900.0 0.23 0.2739 0.9866 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C05 compound treatment 249210.0 -161000.0 -0.91 287250.0 -131000.0 -0.76 -1.1766 -0.9961 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C06 compound treatment 314640.0 -95500.0 -0.54 281040.0 -137000.0 -0.79 -0.9416 -0.982 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C07 compound treatment 340010.0 -70200.0 -0.39 334430.0 -83500.0 -0.48 -0.6217 -0.9949 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C08 compound treatment 303300.0 -107000.0 -0.6 345610.0 -72300.0 -0.42 -0.722 -0.9845 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C09 compound treatment 376320.0 -33800.0 -0.19 360670.0 -57300.0 -0.33 -0.3696 -0.9652 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C10 compound treatment 495780.0 85600.0 0.48 365720.0 -52200.0 -0.3 0.1267 0.2226 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C11 mock treatment 343080.0 -67100.0 -0.38 360540.0 -57400.0 -0.33 -0.5024 -0.998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C12 mock treatment 481120.0 71000.0 0.4 326400.0 -91500.0 -0.53 -0.0929 -0.1399 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C13 compound treatment 313680.0 -96500.0 -0.54 385600.0 -32300.0 -0.19 -0.5167 -0.8991 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C14 compound treatment 142970.0 -267000.0 -1.5 248160.0 -170000.0 -0.98 -1.7598 -0.9789 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C15 mock treatment 260420.0 -150000.0 -0.84 498040.0 80100.0 0.46 -0.2676 -0.278 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C16 mock treatment 306750.0 -103000.0 -0.58 446460.0 28500.0 0.17 -0.2947 -0.4869 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C17 compound treatment 240520.0 -170000.0 -0.96 288100.0 -130000.0 -0.75 -1.2077 -0.9931 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C18 compound treatment 240070.0 -170000.0 -0.96 148500.0 -269000.0 -1.56 -1.782 -0.9724 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C19 compound treatment 204600.0 -206000.0 -1.16 208960.0 -209000.0 -1.21 -1.6753 -0.9997 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C20 compound treatment 198880.0 -211000.0 -1.19 323270.0 -94700.0 -0.55 -1.2293 -0.9383 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C21 compound treatment 238210.0 -172000.0 -0.97 234240.0 -184000.0 -1.07 -1.4378 -0.9989 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C22 compound treatment 197960.0 -212000.0 -1.19 256320.0 -162000.0 -0.94 -1.5075 -0.9928 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C23 compound treatment 247850.0 -162000.0 -0.91 325920.0 -92000.0 -0.53 -1.0235 -0.9672 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 C24 compound treatment 253840.0 -156000.0 -0.88 326400.0 -91500.0 -0.53 -0.9977 -0.9707 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D01 compound treatment 520210.0 110000.0 0.62 488480.0 70500.0 0.41 0.7273 0.9797 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D02 compound treatment 441550.0 31400.0 0.18 477820.0 59900.0 0.35 0.3705 0.9509 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D03 compound treatment 428480.0 18300.0 0.1 428640.0 10700.0 0.06 0.1168 0.9705 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D04 compound treatment 374350.0 -35800.0 -0.2 325520.0 -92400.0 -0.54 -0.5215 -0.9108 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D05 compound treatment 544830.0 135000.0 0.76 513500.0 95600.0 0.55 0.9279 0.9881 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D06 compound treatment 243740.0 -166000.0 -0.94 292200.0 -126000.0 -0.73 -1.1781 -0.9923 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D07 compound treatment 486680.0 76500.0 0.43 577600.0 160000.0 0.93 0.9593 0.9394 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D08 compound treatment 478590.0 68400.0 0.39 536960.0 119000.0 0.69 0.7605 0.962 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D09 compound treatment 518960.0 109000.0 0.61 474570.0 56600.0 0.33 0.6653 0.9573 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D10 compound treatment 450350.0 40200.0 0.23 540190.0 122000.0 0.71 0.6613 0.8886 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D11 mock treatment 536930.0 127000.0 0.71 401250.0 -16700.0 -0.1 0.4362 0.6057 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D12 mock treatment 513820.0 104000.0 0.58 456540.0 38600.0 0.22 0.5709 0.9135 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D13 compound treatment 567900.0 158000.0 0.89 560660.0 143000.0 0.83 1.2132 0.9994 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D14 compound treatment 456000.0 45800.0 0.26 501250.0 83300.0 0.48 0.5241 0.9568 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D15 mock treatment 507760.0 97600.0 0.55 374630.0 -43300.0 -0.25 0.2109 0.3491 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D16 mock treatment 425850.0 15700.0 0.09 347750.0 -70200.0 -0.41 -0.2254 -0.5411 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D17 compound treatment 455800.0 45600.0 0.26 422160.0 4230.0 0.02 0.199 0.7711 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D18 compound treatment 419860.0 9690.0 0.05 434240.0 16300.0 0.09 0.1055 0.9659 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D19 compound treatment 232670.0 -177000.0 -1.0 469940.0 52000.0 0.3 -0.4933 -0.4726 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D20 compound treatment 202580.0 -208000.0 -1.17 299800.0 -118000.0 -0.69 -1.3108 -0.9676 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D21 compound treatment 361570.0 -48600.0 -0.27 427070.0 9140.0 0.05 -0.156 -0.5598 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D22 compound treatment 403050.0 -7120.0 -0.04 408930.0 -9000.0 -0.05 -0.0653 -0.9914 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D23 compound treatment 467490.0 57300.0 0.32 345340.0 -72600.0 -0.42 -0.0695 -0.131 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 D24 compound treatment 301300.0 -109000.0 -0.61 309440.0 -108000.0 -0.63 -0.8783 -0.9999 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E01 mock treatment 507270.0 97100.0 0.55 471580.0 53600.0 0.31 0.6065 0.9643 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E02 mock treatment 375760.0 -34400.0 -0.19 524260.0 106000.0 0.62 0.2991 0.4627 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E03 compound treatment 442200.0 32000.0 0.18 289140.0 -129000.0 -0.75 -0.4006 -0.5214 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E04 compound treatment 498770.0 88600.0 0.5 494670.0 76700.0 0.45 0.6674 0.9984 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E05 compound treatment 389120.0 -21000.0 -0.12 369670.0 -48300.0 -0.28 -0.2817 -0.9268 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E06 compound treatment 432600.0 22400.0 0.13 452580.0 34600.0 0.2 0.2314 0.975 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E07 compound treatment 418180.0 8010.0 0.05 527650.0 110000.0 0.64 0.4818 0.7553 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E08 compound treatment 300540.0 -110000.0 -0.62 466010.0 48100.0 0.28 -0.2392 -0.3533 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E09 mock treatment 508180.0 98000.0 0.55 516420.0 98500.0 0.57 0.794 0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E10 mock treatment 392230.0 -17900.0 -0.1 391760.0 -26200.0 -0.15 -0.1787 -0.9804 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E11 compound treatment 330290.0 -79900.0 -0.45 391040.0 -26900.0 -0.16 -0.4283 -0.8998 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E12 compound treatment 319740.0 -90400.0 -0.51 269410.0 -149000.0 -0.86 -0.969 -0.9685 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E13 compound treatment 418490.0 8320.0 0.05 362620.0 -55300.0 -0.32 -0.1937 -0.5975 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E14 compound treatment 327050.0 -83100.0 -0.47 451740.0 33800.0 0.2 -0.1922 -0.3789 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E15 compound treatment 419200.0 9030.0 0.05 342670.0 -75300.0 -0.44 -0.2727 -0.6205 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E16 compound treatment 177760.0 -232000.0 -1.31 111130.0 -307000.0 -1.78 -2.1833 -0.9886 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E17 mock treatment 354690.0 -55500.0 -0.31 400120.0 -17800.0 -0.1 -0.2939 -0.8934 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E18 mock treatment 317800.0 -92400.0 -0.52 492450.0 74500.0 0.43 -0.0621 -0.0919 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E19 compound treatment 275400.0 -135000.0 -0.76 288920.0 -129000.0 -0.75 -1.0655 -1.0 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E20 compound treatment 271630.0 -139000.0 -0.78 361440.0 -56500.0 -0.33 -0.7831 -0.9258 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E21 compound treatment 243930.0 -166000.0 -0.94 249470.0 -168000.0 -0.98 -1.3526 -0.9998 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E22 compound treatment 334920.0 -75200.0 -0.42 377630.0 -40300.0 -0.23 -0.4648 -0.9607 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E23 compound treatment 186960.0 -223000.0 -1.26 255590.0 -162000.0 -0.94 -1.5543 -0.9899 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 E24 compound treatment 231550.0 -179000.0 -1.01 294170.0 -124000.0 -0.72 -1.2185 -0.9863 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F01 mock treatment 441920.0 31800.0 0.18 386090.0 -31800.0 -0.18 -0.0042 -0.0163 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F02 mock treatment 333760.0 -76400.0 -0.43 361850.0 -56100.0 -0.33 -0.5341 -0.9905 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F03 compound treatment 518360.0 108000.0 0.61 306970.0 -111000.0 -0.64 -0.0244 -0.0275 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F04 compound treatment 284210.0 -126000.0 -0.71 261240.0 -157000.0 -0.91 -1.144 -0.9925 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F05 compound treatment 319430.0 -90700.0 -0.51 368840.0 -49100.0 -0.28 -0.5625 -0.9619 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F06 compound treatment 371650.0 -38500.0 -0.22 431880.0 13900.0 0.08 -0.0961 -0.4154 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F07 compound treatment 363720.0 -46400.0 -0.26 436920.0 19000.0 0.11 -0.107 -0.3773 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F08 compound treatment 494810.0 84600.0 0.48 417160.0 -774.0 0.0 0.3338 0.7004 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F09 mock treatment 445370.0 35200.0 0.2 505850.0 87900.0 0.51 0.5007 0.9152 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F10 mock treatment 502810.0 92600.0 0.52 364610.0 -53300.0 -0.31 0.1501 0.2476 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F11 compound treatment 429770.0 19600.0 0.11 389820.0 -28100.0 -0.16 -0.0373 -0.1892 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F12 compound treatment 491290.0 81100.0 0.46 357660.0 -60300.0 -0.35 0.0758 0.1317 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F13 compound treatment 592080.0 182000.0 1.02 294210.0 -124000.0 -0.72 0.2168 0.1734 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F14 compound treatment 254830.0 -155000.0 -0.87 308000.0 -110000.0 -0.64 -1.0692 -0.9879 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F15 compound treatment 390350.0 -19800.0 -0.11 463110.0 45200.0 0.26 0.1064 0.3736 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F16 compound treatment 442810.0 32600.0 0.18 236440.0 -181000.0 -1.05 -0.6143 -0.575 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F17 mock treatment 545490.0 135000.0 0.76 501920.0 84000.0 0.49 0.8831 0.9766 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F18 mock treatment 307060.0 -103000.0 -0.58 236610.0 -181000.0 -1.05 -1.154 -0.9608 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F19 compound treatment 356860.0 -53300.0 -0.3 323870.0 -94100.0 -0.55 -0.5979 -0.9604 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F20 compound treatment 339560.0 -70600.0 -0.4 249600.0 -168000.0 -0.98 -0.9714 -0.9216 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F21 compound treatment 356060.0 -54100.0 -0.3 453760.0 35800.0 0.21 -0.0685 -0.1857 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F22 compound treatment 453000.0 42800.0 0.24 248610.0 -169000.0 -0.98 -0.5239 -0.5181 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F23 compound treatment 438300.0 28100.0 0.16 370800.0 -47100.0 -0.27 -0.0813 -0.2573 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 F24 compound treatment 312000.0 -98200.0 -0.55 307200.0 -111000.0 -0.64 -0.8449 -0.9972 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G01 compound treatment 319770.0 -90400.0 -0.51 463760.0 45800.0 0.27 -0.1719 -0.2995 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G02 compound treatment 70750.0 -339000.0 -1.91 143710.0 -274000.0 -1.59 -2.4756 -0.9958 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G03 mock treatment 472690.0 62500.0 0.35 303160.0 -115000.0 -0.67 -0.2218 -0.2946 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G04 mock treatment 531330.0 121000.0 0.68 457040.0 39100.0 0.23 0.6427 0.8941 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G05 compound treatment 362080.0 -48100.0 -0.27 498240.0 80300.0 0.47 0.1379 0.256 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G06 compound treatment 366930.0 -43200.0 -0.24 466590.0 48700.0 0.28 0.0274 0.0736 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G07 compound treatment 259840.0 -150000.0 -0.85 410370.0 -7560.0 -0.04 -0.6294 -0.7428 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G08 compound treatment 345650.0 -64500.0 -0.36 475840.0 57900.0 0.34 -0.0194 -0.0391 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G09 compound treatment 410110.0 -57.2 0.0 515740.0 97800.0 0.57 0.4009 0.7067 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G10 compound treatment 427380.0 17200.0 0.1 468020.0 50100.0 0.29 0.2739 0.8945 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G11 compound treatment 409210.0 -957.0 -0.01 299240.0 -119000.0 -0.69 -0.4906 -0.7126 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G12 compound treatment 476030.0 65900.0 0.37 175910.0 -242000.0 -1.4 -0.7303 -0.5031 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G13 compound treatment 381700.0 -28500.0 -0.16 390720.0 -27200.0 -0.16 -0.2249 -1.0 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G14 compound treatment 518080.0 108000.0 0.61 405290.0 -12600.0 -0.07 0.3777 0.6173 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G15 compound treatment 477170.0 67000.0 0.38 348540.0 -69400.0 -0.4 -0.0179 -0.0324 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G16 compound treatment 412000.0 1830.0 0.01 297010.0 -121000.0 -0.7 -0.4886 -0.6966 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G17 compound treatment 269030.0 -141000.0 -0.79 249010.0 -169000.0 -0.98 -1.2545 -0.9946 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G18 compound treatment 515880.0 106000.0 0.6 336120.0 -81800.0 -0.47 0.0853 0.1121 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G19 mock treatment 297600.0 -113000.0 -0.63 307520.0 -110000.0 -0.64 -0.9009 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G20 mock treatment 455200.0 45000.0 0.25 498030.0 80100.0 0.46 0.5077 0.9594 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G21 compound treatment 250750.0 -159000.0 -0.9 443460.0 25500.0 0.15 -0.5299 -0.5826 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G22 compound treatment 282830.0 -127000.0 -0.72 282200.0 -136000.0 -0.79 -1.0635 -0.9989 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G23 compound treatment 274050.0 -136000.0 -0.77 281450.0 -136000.0 -0.79 -1.1015 -0.9999 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 G24 compound treatment 285480.0 -125000.0 -0.7 388480.0 -29500.0 -0.17 -0.6171 -0.8543 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H01 compound treatment 468610.0 58400.0 0.33 343320.0 -74600.0 -0.43 -0.0733 -0.1349 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H02 compound treatment 336510.0 -73700.0 -0.41 358310.0 -59600.0 -0.35 -0.5377 -0.9959 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H03 mock treatment 268930.0 -141000.0 -0.8 529130.0 111000.0 0.64 -0.1062 -0.1038 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H04 mock treatment 513960.0 104000.0 0.58 463360.0 45400.0 0.26 0.5994 0.9353 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H05 compound treatment 296920.0 -113000.0 -0.64 265610.0 -152000.0 -0.88 -1.0755 -0.9872 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H06 compound treatment 222960.0 -187000.0 -1.05 466440.0 48500.0 0.28 -0.5463 -0.5008 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H07 compound treatment 525370.0 115000.0 0.65 519650.0 102000.0 0.59 0.8757 0.9989 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H08 compound treatment 489940.0 79800.0 0.45 316020.0 -102000.0 -0.59 -0.1004 -0.1352 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H09 compound treatment 342560.0 -67600.0 -0.38 381730.0 -36200.0 -0.21 -0.4176 -0.9607 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H10 compound treatment 341760.0 -68400.0 -0.39 288380.0 -130000.0 -0.75 -0.8036 -0.9518 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H11 compound treatment 327540.0 -82600.0 -0.47 330050.0 -87900.0 -0.51 -0.6893 -0.999 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H12 compound treatment 458170.0 48000.0 0.27 360210.0 -57700.0 -0.33 -0.0456 -0.1061 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H13 compound treatment 544960.0 135000.0 0.76 435430.0 17500.0 0.1 0.6083 0.7946 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H14 compound treatment 249220.0 -161000.0 -0.91 272250.0 -146000.0 -0.84 -1.2381 -0.9994 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H15 compound treatment 519890.0 110000.0 0.62 503740.0 85800.0 0.5 0.7886 0.9943 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H16 compound treatment 376700.0 -33500.0 -0.19 347430.0 -70500.0 -0.41 -0.4223 -0.9381 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H17 compound treatment 248830.0 -161000.0 -0.91 342600.0 -75300.0 -0.44 -0.9512 -0.9437 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H18 compound treatment 439750.0 29600.0 0.17 300670.0 -117000.0 -0.68 -0.3631 -0.5186 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H19 mock treatment 348680.0 -61500.0 -0.35 289830.0 -128000.0 -0.74 -0.7701 -0.9396 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H20 mock treatment 184000.0 -226000.0 -1.27 348210.0 -69700.0 -0.4 -1.1862 -0.888 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H21 compound treatment 284910.0 -125000.0 -0.71 287240.0 -131000.0 -0.76 -1.0346 -0.9993 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H22 compound treatment 189490.0 -221000.0 -1.24 225820.0 -192000.0 -1.11 -1.6663 -0.9985 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H23 compound treatment 215300.0 -195000.0 -1.1 374330.0 -43600.0 -0.25 -0.9545 -0.8479 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 H24 compound treatment 318720.0 -91400.0 -0.51 337990.0 -79900.0 -0.46 -0.6919 -0.9986 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I01 compound treatment 177340.0 -233000.0 -1.31 273600.0 -144000.0 -0.84 -1.5187 -0.9765 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I02 compound treatment 452640.0 42500.0 0.24 509020.0 91100.0 0.53 0.5426 0.9358 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I03 compound treatment 309120.0 -101000.0 -0.57 332960.0 -85000.0 -0.49 -0.7507 -0.9974 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I04 compound treatment 337980.0 -72200.0 -0.41 399450.0 -18500.0 -0.11 -0.3632 -0.8641 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I05 mock treatment 506560.0 96400.0 0.54 460420.0 42500.0 0.25 0.5579 0.9362 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I06 mock treatment 388020.0 -22100.0 -0.12 513730.0 95800.0 0.56 0.3047 0.5351 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I07 compound treatment 472210.0 62000.0 0.35 492170.0 74200.0 0.43 0.5514 0.9946 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I08 compound treatment 368560.0 -41600.0 -0.23 530880.0 113000.0 0.66 0.2975 0.4277 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I09 compound treatment 457890.0 47700.0 0.27 433480.0 15500.0 0.09 0.2537 0.8953 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I10 compound treatment 274040.0 -136000.0 -0.77 465760.0 47800.0 0.28 -0.3458 -0.4242 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I11 compound treatment 393630.0 -16500.0 -0.09 225880.0 -192000.0 -1.11 -0.8534 -0.7635 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I12 compound treatment 327240.0 -82900.0 -0.47 426880.0 8950.0 0.05 -0.2934 -0.6247 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I13 compound treatment 373130.0 -37000.0 -0.21 398030.0 -19900.0 -0.12 -0.2291 -0.9611 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I14 compound treatment 370820.0 -39300.0 -0.22 536330.0 118000.0 0.69 0.3289 0.4559 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I15 compound treatment 421440.0 11300.0 0.06 295470.0 -122000.0 -0.71 -0.4573 -0.6414 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I16 compound treatment 453600.0 43400.0 0.24 496930.0 79000.0 0.46 0.4968 0.9568 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I17 compound treatment 229670.0 -180000.0 -1.02 457240.0 39300.0 0.23 -0.5573 -0.5352 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I18 compound treatment 97210.0 -313000.0 -1.76 200510.0 -217000.0 -1.26 -2.1374 -0.9865 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I19 compound treatment 335160.0 -75000.0 -0.42 305800.0 -112000.0 -0.65 -0.7584 -0.9781 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I20 compound treatment 422290.0 12100.0 0.07 475740.0 57800.0 0.34 0.2853 0.8339 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I21 mock treatment 413940.0 3770.0 0.02 476730.0 58800.0 0.34 0.2561 0.7497 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I22 mock treatment 240850.0 -169000.0 -0.95 220610.0 -197000.0 -1.14 -1.4832 -0.9959 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I23 compound treatment 385990.0 -24200.0 -0.14 214730.0 -203000.0 -1.18 -0.9295 -0.7836 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 I24 compound treatment 293150.0 -117000.0 -0.66 336800.0 -81100.0 -0.47 -0.7985 -0.9864 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J01 compound treatment 204610.0 -206000.0 -1.16 366880.0 -51100.0 -0.3 -1.0276 -0.8603 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J02 compound treatment 150570.0 -260000.0 -1.46 303440.0 -114000.0 -0.66 -1.5029 -0.9363 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J03 compound treatment 517970.0 108000.0 0.61 321920.0 -96000.0 -0.56 0.0354 0.043 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J04 compound treatment 317150.0 -93000.0 -0.52 339280.0 -78700.0 -0.46 -0.6928 -0.9976 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J05 mock treatment 513940.0 104000.0 0.58 462080.0 44100.0 0.26 0.5941 0.9315 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J06 mock treatment 456510.0 46300.0 0.26 327950.0 -90000.0 -0.52 -0.1845 -0.3163 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J07 compound treatment 488260.0 78100.0 0.44 480550.0 62600.0 0.36 0.5676 0.9955 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J08 compound treatment 200800.0 -209000.0 -1.18 167600.0 -250000.0 -1.45 -1.86 -0.9947 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J09 compound treatment 418640.0 8470.0 0.05 373300.0 -44600.0 -0.26 -0.1493 -0.5673 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J10 compound treatment 288960.0 -121000.0 -0.68 298270.0 -120000.0 -0.69 -0.9732 -1.0 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J11 compound treatment 453920.0 43800.0 0.25 309190.0 -109000.0 -0.63 -0.2718 -0.4014 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J12 compound treatment 300080.0 -110000.0 -0.62 289330.0 -129000.0 -0.75 -0.9656 -0.9958 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J13 compound treatment 498770.0 88600.0 0.5 351560.0 -66400.0 -0.38 0.0805 0.1278 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J14 compound treatment 263270.0 -147000.0 -0.83 224110.0 -194000.0 -1.12 -1.3796 -0.9886 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J15 compound treatment 532160.0 122000.0 0.69 467010.0 49100.0 0.28 0.6869 0.9239 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J16 compound treatment 210900.0 -199000.0 -1.12 199970.0 -218000.0 -1.26 -1.687 -0.9982 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J17 compound treatment 377040.0 -33100.0 -0.19 530560.0 113000.0 0.65 0.33 0.4858 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J18 compound treatment 243680.0 -166000.0 -0.94 198130.0 -220000.0 -1.27 -1.5641 -0.9886 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J19 compound treatment 316700.0 -93500.0 -0.53 443120.0 25200.0 0.15 -0.2688 -0.4922 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J20 compound treatment 178000.0 -232000.0 -1.31 210350.0 -208000.0 -1.2 -1.7754 -0.9992 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J21 mock treatment 373570.0 -36600.0 -0.21 500830.0 82900.0 0.48 0.1943 0.3714 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J22 mock treatment 280560.0 -130000.0 -0.73 243200.0 -175000.0 -1.01 -1.2325 -0.987 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J23 compound treatment 271270.0 -139000.0 -0.78 305770.0 -112000.0 -0.65 -1.0129 -0.9958 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 J24 compound treatment 303700.0 -106000.0 -0.6 266740.0 -151000.0 -0.88 -1.0438 -0.9828 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K01 compound treatment 387770.0 -22400.0 -0.13 218500.0 -199000.0 -1.16 -0.907 -0.7796 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K02 compound treatment 403940.0 -6230.0 -0.04 363240.0 -54700.0 -0.32 -0.2491 -0.7805 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K03 compound treatment 154410.0 -256000.0 -1.44 233240.0 -185000.0 -1.07 -1.7755 -0.9894 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K04 compound treatment 417720.0 7550.0 0.04 404040.0 -13900.0 -0.08 -0.0269 -0.2954 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K05 compound treatment 432850.0 22700.0 0.13 212650.0 -205000.0 -1.19 -0.7515 -0.6277 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K06 compound treatment 235400.0 -175000.0 -0.98 288160.0 -130000.0 -0.75 -1.2279 -0.9912 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K07 mock treatment 270660.0 -140000.0 -0.79 351170.0 -66800.0 -0.39 -0.8291 -0.9469 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K08 mock treatment 493280.0 83100.0 0.47 376850.0 -41100.0 -0.24 0.1624 0.3092 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K09 compound treatment 303890.0 -106000.0 -0.6 267710.0 -150000.0 -0.87 -1.0391 -0.9832 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K10 compound treatment 44380.0 -366000.0 -2.06 51840.0 -366000.0 -2.12 -2.9574 -0.9999 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K11 compound treatment 292530.0 -118000.0 -0.66 186080.0 -232000.0 -1.34 -1.4191 -0.9468 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K12 compound treatment 444670.0 34500.0 0.19 367810.0 -50100.0 -0.29 -0.0682 -0.1951 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K13 compound treatment 342890.0 -67300.0 -0.38 361130.0 -56800.0 -0.33 -0.5008 -0.9976 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K14 compound treatment 558840.0 149000.0 0.84 569300.0 151000.0 0.88 1.2125 0.9997 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K15 mock treatment 561820.0 152000.0 0.85 408800.0 -9130.0 -0.05 0.5662 0.662 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K16 mock treatment 478340.0 68200.0 0.38 322210.0 -95700.0 -0.56 -0.1212 -0.1795 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K17 compound treatment 498760.0 88600.0 0.5 451120.0 33200.0 0.19 0.4887 0.9143 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K18 compound treatment 551370.0 141000.0 0.79 323460.0 -94500.0 -0.55 0.1747 0.1809 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K19 compound treatment 278270.0 -132000.0 -0.74 292960.0 -125000.0 -0.72 -1.0375 -0.9999 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K20 compound treatment 446420.0 36300.0 0.2 325340.0 -92600.0 -0.54 -0.2354 -0.4098 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K21 compound treatment 345550.0 -64600.0 -0.36 383900.0 -34000.0 -0.2 -0.3968 -0.9587 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K22 compound treatment 265980.0 -144000.0 -0.81 378190.0 -39700.0 -0.23 -0.7369 -0.8734 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K23 mock treatment 365600.0 -44600.0 -0.25 253440.0 -164000.0 -0.95 -0.852 -0.8637 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 K24 mock treatment 330350.0 -79800.0 -0.45 339390.0 -78500.0 -0.46 -0.6398 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L01 compound treatment 417120.0 6950.0 0.04 310530.0 -107000.0 -0.62 -0.4128 -0.6614 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L02 compound treatment 580570.0 170000.0 0.96 553080.0 135000.0 0.78 1.2325 0.995 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L03 compound treatment 316130.0 -94000.0 -0.53 319170.0 -98800.0 -0.57 -0.7793 -0.9992 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L04 compound treatment 358400.0 -51800.0 -0.29 333620.0 -84300.0 -0.49 -0.5518 -0.9694 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L05 compound treatment 529390.0 119000.0 0.67 359330.0 -58600.0 -0.34 0.2343 0.3114 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L06 compound treatment 168090.0 -242000.0 -1.36 192640.0 -225000.0 -1.31 -1.8875 -0.9998 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L07 mock treatment 425050.0 14900.0 0.08 561300.0 143000.0 0.83 0.6472 0.7744 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L08 mock treatment 419530.0 9360.0 0.05 488000.0 70100.0 0.41 0.3246 0.7922 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L09 compound treatment 239140.0 -171000.0 -0.96 329440.0 -88500.0 -0.51 -1.0437 -0.9566 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L10 compound treatment 232830.0 -177000.0 -1.0 224870.0 -193000.0 -1.12 -1.4976 -0.9984 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L11 compound treatment 517080.0 107000.0 0.6 471170.0 53200.0 0.31 0.6439 0.9519 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L12 compound treatment 427930.0 17800.0 0.1 329190.0 -88700.0 -0.51 -0.2932 -0.5593 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L13 compound treatment 433600.0 23400.0 0.13 504800.0 86900.0 0.5 0.4495 0.8632 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L14 compound treatment 232540.0 -178000.0 -1.0 291480.0 -126000.0 -0.73 -1.2256 -0.9884 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L15 mock treatment 421560.0 11400.0 0.06 567080.0 149000.0 0.86 0.657 0.7575 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L16 mock treatment 548820.0 139000.0 0.78 475260.0 57300.0 0.33 0.787 0.9276 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L17 compound treatment 585530.0 175000.0 0.99 543050.0 125000.0 0.73 1.2111 0.9885 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L18 compound treatment 309690.0 -100000.0 -0.57 273120.0 -145000.0 -0.84 -0.9938 -0.9815 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L19 compound treatment 449960.0 39800.0 0.22 457690.0 39800.0 0.23 0.3214 0.9999 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L20 compound treatment 177120.0 -233000.0 -1.31 270310.0 -148000.0 -0.86 -1.5331 -0.9786 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L21 compound treatment 308320.0 -102000.0 -0.57 438850.0 20900.0 0.12 -0.3196 -0.5454 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L22 compound treatment 223680.0 -186000.0 -1.05 189940.0 -228000.0 -1.32 -1.6773 -0.9935 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L23 mock treatment 399840.0 -10300.0 -0.06 294720.0 -123000.0 -0.71 -0.5464 -0.7621 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 L24 mock treatment 418840.0 8670.0 0.05 519040.0 101000.0 0.59 0.4491 0.7633 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M01 compound treatment 278910.0 -131000.0 -0.74 294670.0 -123000.0 -0.71 -1.028 -0.9999 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M02 compound treatment 535720.0 126000.0 0.71 528860.0 111000.0 0.64 0.9547 0.9989 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M03 compound treatment 442420.0 32300.0 0.18 431920.0 14000.0 0.08 0.1857 0.934 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M04 compound treatment 338900.0 -71300.0 -0.4 494020.0 76100.0 0.44 0.0283 0.0475 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M05 compound treatment 501620.0 91500.0 0.51 353640.0 -64300.0 -0.37 0.1004 0.1579 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M06 compound treatment 356960.0 -53200.0 -0.3 337960.0 -80000.0 -0.46 -0.5398 -0.9776 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M07 compound treatment 556360.0 146000.0 0.82 449780.0 31800.0 0.18 0.7125 0.8448 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M08 compound treatment 324330.0 -85800.0 -0.48 388730.0 -29200.0 -0.17 -0.4615 -0.9012 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M09 mock treatment 296800.0 -113000.0 -0.64 359690.0 -58200.0 -0.34 -0.6901 -0.9557 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M10 mock treatment 578730.0 169000.0 0.95 419840.0 1910.0 0.01 0.6788 0.7153 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M11 compound treatment 496980.0 86800.0 0.49 404910.0 -13000.0 -0.08 0.2922 0.5908 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M12 compound treatment 447490.0 37300.0 0.21 492390.0 74500.0 0.43 0.4539 0.9452 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M13 mock treatment 402300.0 -7870.0 -0.04 406190.0 -11700.0 -0.07 -0.0795 -0.9783 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M14 mock treatment 532010.0 122000.0 0.69 538080.0 120000.0 0.7 0.9777 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M15 compound treatment 535160.0 125000.0 0.7 507040.0 89100.0 0.52 0.863 0.9885 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M16 compound treatment 557880.0 148000.0 0.83 512200.0 94300.0 0.55 0.9746 0.9793 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M17 compound treatment 411650.0 1480.0 0.01 426190.0 8260.0 0.05 0.0398 0.8181 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M18 compound treatment 472380.0 62200.0 0.35 511960.0 94000.0 0.55 0.6332 0.9771 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M19 mock treatment 346080.0 -64100.0 -0.36 521170.0 103000.0 0.6 0.1682 0.2407 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M20 compound treatment 229760.0 -180000.0 -1.02 369290.0 -48600.0 -0.28 -0.9176 -0.8706 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M21 mock treatment 502730.0 92600.0 0.52 453010.0 35100.0 0.2 0.5123 0.9158 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M22 compound treatment 349240.0 -60900.0 -0.34 409770.0 -8160.0 -0.05 -0.276 -0.7972 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M23 mock treatment 428700.0 18500.0 0.1 426100.0 8170.0 0.05 0.1073 0.9361 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 M24 compound treatment 181870.0 -228000.0 -1.29 333550.0 -84400.0 -0.49 -1.2548 -0.9124 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N01 compound treatment 477840.0 67700.0 0.38 424640.0 6710.0 0.04 0.2969 0.7753 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N02 compound treatment 279840.0 -130000.0 -0.73 243390.0 -175000.0 -1.01 -1.2346 -0.9875 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N03 compound treatment 452960.0 42800.0 0.24 330740.0 -87200.0 -0.51 -0.1872 -0.3342 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N04 compound treatment 372000.0 -38200.0 -0.21 515700.0 97800.0 0.57 0.249 0.4106 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N05 compound treatment 404660.0 -5510.0 -0.03 496130.0 78200.0 0.45 0.2987 0.6572 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N06 compound treatment 282080.0 -128000.0 -0.72 263760.0 -154000.0 -0.89 -1.1421 -0.9943 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N07 compound treatment 411320.0 1150.0 0.01 314670.0 -103000.0 -0.6 -0.4189 -0.6994 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N08 compound treatment 413440.0 3270.0 0.02 320840.0 -97100.0 -0.56 -0.3851 -0.6836 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N09 mock treatment 270240.0 -140000.0 -0.79 316220.0 -102000.0 -0.59 -0.9741 -0.9898 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N10 mock treatment 318800.0 -91400.0 -0.51 376480.0 -41500.0 -0.24 -0.5337 -0.94 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N11 compound treatment 406180.0 -3990.0 -0.02 346410.0 -71500.0 -0.41 -0.3092 -0.7443 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N12 compound treatment 391920.0 -18200.0 -0.1 231970.0 -186000.0 -1.08 -0.8352 -0.771 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N13 mock treatment 473920.0 63800.0 0.36 466170.0 48200.0 0.28 0.4516 0.9924 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N14 mock treatment 523840.0 114000.0 0.64 516010.0 98100.0 0.57 0.8547 0.9983 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N15 compound treatment 528430.0 118000.0 0.67 509210.0 91300.0 0.53 0.8451 0.9935 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N16 compound treatment 399210.0 -11000.0 -0.06 550790.0 133000.0 0.77 0.5012 0.6484 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N17 compound treatment 273220.0 -137000.0 -0.77 429700.0 11800.0 0.07 -0.4969 -0.642 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N18 compound treatment 261760.0 -148000.0 -0.84 332970.0 -85000.0 -0.49 -0.9392 -0.9683 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N19 compound treatment 567110.0 157000.0 0.88 414900.0 -3030.0 -0.02 0.6123 0.6929 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N20 compound treatment 162450.0 -248000.0 -1.39 155440.0 -262000.0 -1.52 -2.0625 -0.999 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N21 compound treatment 386990.0 -23200.0 -0.13 503410.0 85500.0 0.5 0.2583 0.5038 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N22 compound treatment 166170.0 -244000.0 -1.37 262020.0 -156000.0 -0.9 -1.6106 -0.9794 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N23 compound treatment 306630.0 -104000.0 -0.58 391290.0 -26600.0 -0.15 -0.5214 -0.8647 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 N24 compound treatment 209830.0 -200000.0 -1.13 226940.0 -191000.0 -1.11 -1.5807 -1.0 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O01 mock treatment 475950.0 65800.0 0.37 476760.0 58800.0 0.34 0.5031 0.9992 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O02 compound treatment 337450.0 -72700.0 -0.41 231130.0 -187000.0 -1.08 -1.0555 -0.9114 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O03 mock treatment 362290.0 -47900.0 -0.27 455880.0 37900.0 0.22 -0.035 -0.1005 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O04 mock treatment 336170.0 -74000.0 -0.42 539600.0 122000.0 0.71 0.2044 0.2494 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O05 mock treatment 534170.0 124000.0 0.7 545370.0 127000.0 0.74 1.0162 0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O06 mock treatment 418940.0 8770.0 0.05 421770.0 3840.0 0.02 0.0507 0.9351 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O07 mock treatment 466340.0 56200.0 0.32 363710.0 -54200.0 -0.31 0.0012 0.0028 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O08 mock treatment 379210.0 -31000.0 -0.17 511090.0 93200.0 0.54 0.2588 0.4559 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O09 mock treatment 360690.0 -49500.0 -0.28 229940.0 -188000.0 -1.09 -0.9679 -0.8601 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O10 mock treatment 536700.0 127000.0 0.71 367130.0 -50800.0 -0.29 0.2953 0.3831 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O11 mock treatment 441570.0 31400.0 0.18 380260.0 -37700.0 -0.22 -0.0295 -0.1049 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O12 mock treatment 476080.0 65900.0 0.37 481360.0 63400.0 0.37 0.5225 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O13 mock treatment 375200.0 -35000.0 -0.2 407770.0 -10200.0 -0.06 -0.1809 -0.8802 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O14 mock treatment 478210.0 68000.0 0.38 382040.0 -35900.0 -0.21 0.1237 0.2837 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O15 mock treatment 389820.0 -20300.0 -0.11 463200.0 45300.0 0.26 0.1046 0.3653 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O16 mock treatment 482090.0 71900.0 0.4 471840.0 53900.0 0.31 0.5074 0.9918 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O17 mock treatment 334490.0 -75700.0 -0.43 431080.0 13100.0 0.08 -0.2473 -0.5715 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O18 mock treatment 224030.0 -186000.0 -1.05 525070.0 107000.0 0.62 -0.3016 -0.2476 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O19 mock treatment 366670.0 -43500.0 -0.24 400750.0 -17200.0 -0.1 -0.2436 -0.9215 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O20 mock treatment 391430.0 -18700.0 -0.11 558170.0 140000.0 0.81 0.5005 0.6103 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O21 mock treatment 361130.0 -49000.0 -0.28 428060.0 10100.0 0.06 -0.1537 -0.5445 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O22 mock treatment 348090.0 -62100.0 -0.35 424580.0 6650.0 0.04 -0.2199 -0.6253 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O23 mock treatment 393440.0 -16700.0 -0.09 517360.0 99400.0 0.58 0.3411 0.5839 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 O24 mock treatment 467520.0 57400.0 0.32 410750.0 -7180.0 -0.04 0.1988 0.6108 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P01 compound treatment 460160.0 50000.0 0.28 322830.0 -95100.0 -0.55 -0.191 -0.3085 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P02 compound treatment 389010.0 -21200.0 -0.12 298650.0 -119000.0 -0.69 -0.5734 -0.8168 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P03 compound treatment 356030.0 -54100.0 -0.3 319140.0 -98800.0 -0.57 -0.6206 -0.9564 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P04 compound treatment 150770.0 -259000.0 -1.46 209600.0 -208000.0 -1.21 -1.8869 -0.9956 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P05 compound treatment 363470.0 -46700.0 -0.26 181840.0 -236000.0 -1.37 -1.1541 -0.8278 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P06 compound treatment 388110.0 -22100.0 -0.12 444000.0 26100.0 0.15 0.0191 0.0976 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P07 compound treatment 361920.0 -48200.0 -0.27 276990.0 -141000.0 -0.82 -0.77 -0.894 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P08 compound treatment 234400.0 -176000.0 -0.99 260990.0 -157000.0 -0.91 -1.3433 -0.9991 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P09 compound treatment 419650.0 9480.0 0.05 417720.0 -214.0 0.0 0.0369 0.6905 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P10 compound treatment 230340.0 -180000.0 -1.01 284000.0 -134000.0 -0.78 -1.2651 -0.9914 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P11 mock treatment 235230.0 -175000.0 -0.98 257300.0 -161000.0 -0.93 -1.3551 -0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P12 mock treatment 267640.0 -143000.0 -0.8 287120.0 -131000.0 -0.76 -1.1038 -0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P13 compound treatment 276930.0 -133000.0 -0.75 258560.0 -159000.0 -0.92 -1.1839 -0.9946 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P14 compound treatment 270350.0 -140000.0 -0.79 194670.0 -223000.0 -1.29 -1.4721 -0.9715 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P15 compound treatment 268380.0 -142000.0 -0.8 211370.0 -207000.0 -1.2 -1.4115 -0.9805 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P16 compound treatment 236590.0 -174000.0 -0.98 251100.0 -167000.0 -0.97 -1.3751 -1.0 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P17 compound treatment 317020.0 -93100.0 -0.52 360700.0 -57200.0 -0.33 -0.6055 -0.9757 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P18 compound treatment 116960.0 -293000.0 -1.65 170630.0 -247000.0 -1.43 -2.1813 -0.9975 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P19 compound treatment 157060.0 -253000.0 -1.42 352090.0 -65800.0 -0.38 -1.2776 -0.866 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P20 compound treatment 131080.0 -279000.0 -1.57 159420.0 -259000.0 -1.5 -2.1711 -0.9997 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P21 compound treatment 236960.0 -173000.0 -0.98 310950.0 -107000.0 -0.62 -1.1282 -0.9762 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P22 compound treatment 233510.0 -177000.0 -0.99 239360.0 -179000.0 -1.04 -1.4355 -0.9998 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P23 compound treatment 381610.0 -28600.0 -0.16 299130.0 -119000.0 -0.69 -0.6009 -0.8493 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2130 P24 compound treatment 215330.0 -195000.0 -1.1 264650.0 -153000.0 -0.89 -1.4042 -0.9946 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A01 compound treatment 239880.0 -244000.0 -1.37 260100.0 -149000.0 -0.86 -1.5825 -0.975 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A02 compound treatment 398800.0 -85100.0 -0.48 321780.0 -87300.0 -0.51 -0.6969 -0.9996 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A03 compound treatment 402970.0 -80900.0 -0.46 500640.0 91500.0 0.53 0.0531 0.0759 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A04 compound treatment 447710.0 -36200.0 -0.2 277280.0 -132000.0 -0.76 -0.6847 -0.8654 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A05 compound treatment 287520.0 -196000.0 -1.11 224860.0 -184000.0 -1.07 -1.5374 -0.9999 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A06 compound treatment 211100.0 -273000.0 -1.54 126760.0 -282000.0 -1.64 -2.2439 -0.9995 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A07 compound treatment 240160.0 -244000.0 -1.37 165120.0 -244000.0 -1.42 -1.9709 -0.9999 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A08 compound treatment 502190.0 18300.0 0.1 260840.0 -148000.0 -0.86 -0.5353 -0.6181 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A09 compound treatment 139720.0 -344000.0 -1.94 108270.0 -301000.0 -1.74 -2.6038 -0.9986 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A10 compound treatment 274310.0 -210000.0 -1.18 262480.0 -147000.0 -0.85 -1.4357 -0.9871 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A11 compound treatment 238450.0 -245000.0 -1.38 283410.0 -126000.0 -0.73 -1.4926 -0.9554 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A12 compound treatment 401690.0 -82200.0 -0.46 356010.0 -53100.0 -0.31 -0.5451 -0.9804 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A13 mock treatment 547710.0 63800.0 0.36 211630.0 -197000.0 -1.15 -0.5559 -0.4631 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A14 mock treatment 417080.0 -66800.0 -0.38 378750.0 -30400.0 -0.18 -0.3906 -0.9402 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A15 compound treatment 257020.0 -227000.0 -1.28 356970.0 -52100.0 -0.3 -1.117 -0.851 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A16 compound treatment 487890.0 3980.0 0.02 412070.0 2950.0 0.02 0.028 0.9912 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A17 compound treatment 266920.0 -217000.0 -1.22 291690.0 -117000.0 -0.68 -1.3453 -0.9619 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A18 compound treatment 444930.0 -39000.0 -0.22 368770.0 -40300.0 -0.23 -0.3206 -0.9995 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A19 compound treatment 521990.0 38100.0 0.21 380260.0 -28900.0 -0.17 0.0332 0.1223 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A20 compound treatment 361730.0 -122000.0 -0.69 201400.0 -208000.0 -1.2 -1.3382 -0.9647 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A21 compound treatment 265350.0 -219000.0 -1.23 196240.0 -213000.0 -1.23 -1.743 -1.0 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A22 compound treatment 527390.0 43500.0 0.24 481450.0 72300.0 0.42 0.4697 0.9671 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A23 compound treatment 368320.0 -116000.0 -0.65 299470.0 -110000.0 -0.64 -0.9098 -0.9999 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 A24 compound treatment 335490.0 -148000.0 -0.84 187850.0 -221000.0 -1.28 -1.4982 -0.9784 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B01 compound treatment 611410.0 128000.0 0.72 557410.0 148000.0 0.86 1.1157 0.996 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B02 compound treatment 435730.0 -48200.0 -0.27 464070.0 55000.0 0.32 0.0336 0.0802 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B03 compound treatment 173370.0 -311000.0 -1.75 217500.0 -192000.0 -1.11 -2.0219 -0.9761 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B04 compound treatment 225520.0 -258000.0 -1.45 270410.0 -139000.0 -0.8 -1.5974 -0.961 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B05 compound treatment 477550.0 -6360.0 -0.04 503040.0 93900.0 0.54 0.3598 0.6592 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B06 compound treatment 313120.0 -171000.0 -0.96 402400.0 -6720.0 -0.04 -0.7074 -0.7352 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B07 compound treatment 266950.0 -217000.0 -1.22 236570.0 -173000.0 -1.0 -1.5712 -0.9951 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B08 compound treatment 306900.0 -177000.0 -1.0 167010.0 -242000.0 -1.4 -1.6975 -0.9859 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B09 compound treatment 593770.0 110000.0 0.62 341950.0 -67200.0 -0.39 0.1619 0.2215 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B10 compound treatment 592930.0 109000.0 0.61 485550.0 76400.0 0.44 0.7474 0.9872 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B11 compound treatment 436330.0 -47600.0 -0.27 504930.0 95800.0 0.56 0.2035 0.3299 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B12 compound treatment 154960.0 -329000.0 -1.85 156450.0 -253000.0 -1.47 -2.3456 -0.9933 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B13 mock treatment 330880.0 -153000.0 -0.86 385020.0 -24100.0 -0.14 -0.708 -0.8112 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B14 mock treatment 524550.0 40600.0 0.23 513050.0 104000.0 0.6 0.588 0.912 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B15 compound treatment 406400.0 -77500.0 -0.44 203400.0 -206000.0 -1.19 -1.1521 -0.907 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B16 compound treatment 14680.0 -469000.0 -2.64 10080.0 -399000.0 -2.31 -3.5042 -0.9978 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B17 compound treatment 515620.0 31700.0 0.18 367040.0 -42100.0 -0.24 -0.0463 -0.1532 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B18 compound treatment 595950.0 112000.0 0.63 466670.0 57600.0 0.33 0.682 0.9557 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B19 compound treatment 535210.0 51300.0 0.29 362080.0 -47000.0 -0.27 0.0113 0.0285 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B20 compound treatment 435270.0 -48600.0 -0.27 439590.0 30500.0 0.18 -0.0687 -0.2107 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B21 compound treatment 547320.0 63400.0 0.36 438310.0 29200.0 0.17 0.3721 0.9419 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B22 compound treatment 15000.0 -469000.0 -2.64 12380.0 -397000.0 -2.3 -3.4935 -0.9977 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B23 compound treatment 363200.0 -121000.0 -0.68 347790.0 -61300.0 -0.36 -0.732 -0.9544 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 B24 compound treatment 57760.0 -426000.0 -2.4 12080.0 -397000.0 -2.3 -3.3245 -0.9998 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C01 compound treatment 270300.0 -214000.0 -1.2 493220.0 84100.0 0.49 -0.5054 -0.3895 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C02 compound treatment 332420.0 -151000.0 -0.85 425120.0 16000.0 0.09 -0.5374 -0.6265 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C03 compound treatment 273320.0 -211000.0 -1.19 232480.0 -177000.0 -1.02 -1.5626 -0.9974 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C04 compound treatment 526680.0 42800.0 0.24 226050.0 -183000.0 -1.06 -0.5805 -0.5332 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C05 compound treatment 16360.0 -468000.0 -2.63 12390.0 -397000.0 -2.3 -3.4881 -0.9978 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C06 compound treatment 497950.0 14000.0 0.08 331490.0 -77600.0 -0.45 -0.2624 -0.5742 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C07 compound treatment 541780.0 57900.0 0.33 292920.0 -116000.0 -0.67 -0.2461 -0.3288 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C08 compound treatment 441040.0 -42900.0 -0.24 382080.0 -27000.0 -0.16 -0.2815 -0.9782 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C09 compound treatment 456360.0 -27500.0 -0.16 282880.0 -126000.0 -0.73 -0.6273 -0.8383 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C10 compound treatment 383070.0 -101000.0 -0.57 267320.0 -142000.0 -0.82 -0.9829 -0.9836 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C11 mock treatment 316480.0 -167000.0 -0.94 435440.0 26300.0 0.15 -0.5585 -0.585 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C12 mock treatment 407840.0 -76100.0 -0.43 365760.0 -43400.0 -0.25 -0.4806 -0.9678 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C13 compound treatment 449930.0 -34000.0 -0.19 241850.0 -167000.0 -0.97 -0.8212 -0.8305 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C14 compound treatment 424480.0 -59400.0 -0.33 402760.0 -6360.0 -0.04 -0.2626 -0.7803 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C15 mock treatment 382960.0 -101000.0 -0.57 368980.0 -40100.0 -0.23 -0.5664 -0.9224 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C16 mock treatment 431360.0 -52500.0 -0.3 427060.0 17900.0 0.1 -0.1356 -0.4324 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C17 compound treatment 320200.0 -164000.0 -0.92 318470.0 -90600.0 -0.53 -1.0234 -0.9646 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C18 compound treatment 401950.0 -82000.0 -0.46 283680.0 -125000.0 -0.73 -0.8406 -0.9759 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C19 compound treatment 461920.0 -22000.0 -0.12 324260.0 -84900.0 -0.49 -0.4355 -0.8582 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C20 compound treatment 445460.0 -38400.0 -0.22 308640.0 -100000.0 -0.58 -0.5651 -0.9091 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C21 compound treatment 471930.0 -12000.0 -0.07 385330.0 -23800.0 -0.14 -0.1452 -0.9458 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C22 compound treatment 432280.0 -51600.0 -0.29 343780.0 -65300.0 -0.38 -0.4735 -0.9914 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C23 compound treatment 542350.0 58400.0 0.33 454970.0 45900.0 0.27 0.4207 0.9944 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 C24 compound treatment 366240.0 -118000.0 -0.66 335570.0 -73500.0 -0.43 -0.77 -0.9773 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D01 compound treatment 533160.0 49300.0 0.28 536360.0 127000.0 0.74 0.7178 0.9106 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D02 compound treatment 583390.0 99500.0 0.56 451270.0 42200.0 0.24 0.5689 0.9309 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D03 compound treatment 527060.0 43200.0 0.24 489710.0 80600.0 0.47 0.5023 0.9535 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D04 compound treatment 440280.0 -43600.0 -0.25 400320.0 -8800.0 -0.05 -0.2097 -0.8361 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D05 compound treatment 193510.0 -290000.0 -1.63 182600.0 -227000.0 -1.31 -2.0849 -0.9941 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D06 compound treatment 544210.0 60300.0 0.34 396440.0 -12700.0 -0.07 0.1881 0.5414 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D07 compound treatment 544960.0 61100.0 0.34 461840.0 52700.0 0.31 0.4592 0.9983 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D08 compound treatment 455230.0 -28700.0 -0.16 261180.0 -148000.0 -0.86 -0.7208 -0.8257 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D09 compound treatment 371520.0 -112000.0 -0.63 342080.0 -67000.0 -0.39 -0.7223 -0.9727 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D10 compound treatment 273840.0 -210000.0 -1.18 306730.0 -102000.0 -0.59 -1.2561 -0.9492 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D11 mock treatment 543010.0 59100.0 0.33 515080.0 106000.0 0.61 0.6698 0.9585 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D12 mock treatment 548890.0 65000.0 0.37 305930.0 -103000.0 -0.6 -0.1645 -0.2345 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D13 compound treatment 458970.0 -24900.0 -0.14 381610.0 -27500.0 -0.16 -0.2121 -0.998 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D14 compound treatment 537710.0 53800.0 0.3 235770.0 -173000.0 -1.01 -0.4967 -0.4731 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D15 mock treatment 546620.0 62700.0 0.35 501640.0 92500.0 0.54 0.629 0.9794 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D16 mock treatment 564900.0 81000.0 0.46 528610.0 119000.0 0.69 0.8124 0.9794 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D17 compound treatment 622400.0 138000.0 0.78 545650.0 137000.0 0.79 1.1112 1.0 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D18 compound treatment 483700.0 -209.0 0.0 407630.0 -1490.0 -0.01 -0.0069 -0.7963 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D19 compound treatment 498890.0 15000.0 0.08 318720.0 -90400.0 -0.52 -0.3111 -0.5858 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D20 compound treatment 472130.0 -11800.0 -0.07 252260.0 -157000.0 -0.91 -0.6901 -0.7566 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D21 compound treatment 483550.0 -359.0 0.0 450750.0 41600.0 0.24 0.1693 0.7012 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D22 compound treatment 559560.0 75700.0 0.43 392220.0 -16900.0 -0.1 0.2318 0.5305 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D23 compound treatment 425830.0 -58100.0 -0.33 345630.0 -63500.0 -0.37 -0.4915 -0.9982 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 D24 compound treatment 274890.0 -209000.0 -1.18 279870.0 -129000.0 -0.75 -1.3621 -0.9763 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E01 mock treatment 565300.0 81400.0 0.46 509480.0 100000.0 0.58 0.7356 0.993 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E02 mock treatment 585000.0 101000.0 0.57 439200.0 30100.0 0.17 0.5258 0.8833 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E03 compound treatment 613280.0 129000.0 0.73 262830.0 -146000.0 -0.85 -0.0849 -0.0759 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E04 compound treatment 521950.0 38000.0 0.21 382940.0 -26200.0 -0.15 0.0441 0.1679 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E05 compound treatment 411940.0 -72000.0 -0.41 461670.0 52600.0 0.3 -0.071 -0.14 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E06 compound treatment 482040.0 -1870.0 -0.01 423310.0 14200.0 0.08 0.0508 0.6117 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E07 compound treatment 374080.0 -110000.0 -0.62 411210.0 2090.0 0.01 -0.4286 -0.6931 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E08 compound treatment 436980.0 -46900.0 -0.26 329060.0 -80100.0 -0.46 -0.5151 -0.9643 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E09 mock treatment 569950.0 86000.0 0.48 443330.0 34200.0 0.2 0.4828 0.9224 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E10 mock treatment 528550.0 44600.0 0.25 466730.0 57600.0 0.33 0.414 0.9901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E11 compound treatment 484640.0 731.0 0.0 285230.0 -124000.0 -0.72 -0.5051 -0.703 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E12 compound treatment 448870.0 -35000.0 -0.2 441480.0 32400.0 0.19 -0.0068 -0.0248 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E13 compound treatment 441990.0 -41900.0 -0.24 331140.0 -78000.0 -0.45 -0.4866 -0.954 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E14 compound treatment 474790.0 -9120.0 -0.05 483400.0 74300.0 0.43 0.2683 0.6185 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E15 compound treatment 516540.0 32600.0 0.18 459900.0 50800.0 0.29 0.3381 0.9742 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E16 compound treatment 481440.0 -2470.0 -0.01 418880.0 9760.0 0.06 0.0302 0.5181 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E17 mock treatment 571730.0 87800.0 0.49 346430.0 -62700.0 -0.36 0.0925 0.1508 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E18 mock treatment 590950.0 107000.0 0.6 400960.0 -8160.0 -0.05 0.3926 0.6496 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E19 compound treatment 356210.0 -128000.0 -0.72 252640.0 -156000.0 -0.91 -1.15 -0.9933 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E20 compound treatment 380860.0 -103000.0 -0.58 422050.0 12900.0 0.08 -0.3572 -0.6106 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E21 compound treatment 442690.0 -41200.0 -0.23 313460.0 -95700.0 -0.55 -0.5564 -0.9252 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E22 compound treatment 439890.0 -44000.0 -0.25 392250.0 -16900.0 -0.1 -0.2444 -0.9173 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E23 compound treatment 506940.0 23000.0 0.13 318620.0 -90500.0 -0.52 -0.2794 -0.5169 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 E24 compound treatment 435410.0 -48500.0 -0.27 416410.0 7290.0 0.04 -0.1632 -0.5905 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F01 mock treatment 574500.0 90600.0 0.51 550880.0 142000.0 0.82 0.942 0.9736 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F02 mock treatment 237450.0 -246000.0 -1.39 401010.0 -8110.0 -0.05 -1.0143 -0.7306 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F03 compound treatment 341920.0 -142000.0 -0.8 251520.0 -158000.0 -0.91 -1.2115 -0.9978 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F04 compound treatment 410720.0 -73200.0 -0.41 346880.0 -62200.0 -0.36 -0.5466 -0.9978 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F05 compound treatment 559290.0 75400.0 0.42 321570.0 -87500.0 -0.51 -0.0589 -0.0891 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F06 compound treatment 348070.0 -136000.0 -0.76 304050.0 -105000.0 -0.61 -0.9716 -0.9937 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F07 compound treatment 318980.0 -165000.0 -0.93 232440.0 -177000.0 -1.02 -1.381 -0.9988 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F08 compound treatment 520190.0 36300.0 0.2 449410.0 40300.0 0.23 0.3097 0.9977 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F09 mock treatment 291460.0 -192000.0 -1.08 397190.0 -11900.0 -0.07 -0.815 -0.7507 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F10 mock treatment 452870.0 -31000.0 -0.17 423360.0 14200.0 0.08 -0.0651 -0.3371 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F11 compound treatment 410980.0 -72900.0 -0.41 428750.0 19600.0 0.11 -0.2098 -0.4924 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F12 compound treatment 303750.0 -180000.0 -1.01 256500.0 -153000.0 -0.89 -1.343 -0.9977 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F13 compound treatment 225330.0 -259000.0 -1.46 192420.0 -217000.0 -1.26 -1.918 -0.9973 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F14 compound treatment 343040.0 -141000.0 -0.79 333280.0 -75800.0 -0.44 -0.8717 -0.9613 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F15 compound treatment 600210.0 116000.0 0.65 401120.0 -8000.0 -0.05 0.4302 0.6554 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F16 compound treatment 435480.0 -48400.0 -0.27 427940.0 18800.0 0.11 -0.1156 -0.3936 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F17 mock treatment 409440.0 -74500.0 -0.42 425550.0 16400.0 0.1 -0.229 -0.5328 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F18 mock treatment 569760.0 85900.0 0.48 277050.0 -132000.0 -0.77 -0.1998 -0.2207 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F19 compound treatment 423170.0 -60700.0 -0.34 325020.0 -84100.0 -0.49 -0.5866 -0.9849 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F20 compound treatment 107110.0 -377000.0 -2.12 98880.0 -310000.0 -1.8 -2.7721 -0.9966 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F21 compound treatment 520580.0 36700.0 0.21 388900.0 -20200.0 -0.12 0.0631 0.2656 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F22 compound treatment 262370.0 -222000.0 -1.25 330720.0 -78400.0 -0.45 -1.2034 -0.9065 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F23 compound treatment 405450.0 -78500.0 -0.44 218180.0 -191000.0 -1.11 -1.0953 -0.9188 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 F24 compound treatment 504720.0 20800.0 0.12 414190.0 5070.0 0.03 0.1036 0.858 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G01 compound treatment 480320.0 -3590.0 -0.02 399160.0 -9960.0 -0.06 -0.0551 -0.901 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G02 compound treatment 494760.0 10900.0 0.06 242800.0 -166000.0 -0.96 -0.6388 -0.661 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G03 mock treatment 621840.0 138000.0 0.78 384320.0 -24800.0 -0.14 0.4474 0.5665 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G04 mock treatment 329320.0 -155000.0 -0.87 265360.0 -144000.0 -0.83 -1.2049 -0.9998 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G05 compound treatment 173480.0 -310000.0 -1.75 169680.0 -239000.0 -1.39 -2.2176 -0.9935 PK04_181123 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G06 compound treatment 537890.0 54000.0 0.3 305190.0 -104000.0 -0.6 -0.2113 -0.313 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G07 compound treatment 504840.0 20900.0 0.12 332770.0 -76300.0 -0.44 -0.2298 -0.5015 PK04_181125 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G08 compound treatment 617940.0 134000.0 0.75 333790.0 -75300.0 -0.44 0.2246 0.2576 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G09 compound treatment 572480.0 88600.0 0.5 209440.0 -200000.0 -1.16 -0.4663 -0.3698 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G10 compound treatment 484530.0 621.0 0.0 270560.0 -139000.0 -0.8 -0.5657 -0.704 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G11 compound treatment 486880.0 2970.0 0.02 471680.0 62600.0 0.36 0.2684 0.7389 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G12 compound treatment 384290.0 -99600.0 -0.56 253090.0 -156000.0 -0.9 -1.0364 -0.9735 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G13 compound treatment 463430.0 -20500.0 -0.12 344880.0 -64200.0 -0.37 -0.3449 -0.8845 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G14 compound treatment 485210.0 1300.0 0.01 267240.0 -142000.0 -0.82 -0.5766 -0.7008 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G15 compound treatment 327420.0 -156000.0 -0.88 274200.0 -135000.0 -0.78 -1.1762 -0.9983 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G16 compound treatment 557520.0 73600.0 0.41 362470.0 -46600.0 -0.27 0.1017 0.2056 3561954 PK04_181134 COc1ccccc1/C=C/CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G17 compound treatment 528210.0 44300.0 0.25 349760.0 -59400.0 -0.34 -0.0671 -0.1578 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G18 compound treatment 542750.0 58800.0 0.33 394800.0 -14300.0 -0.08 0.1755 0.514 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G19 mock treatment 512240.0 28300.0 0.16 378820.0 -30300.0 -0.18 -0.0115 -0.0483 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G20 mock treatment 438430.0 -45500.0 -0.26 365190.0 -43900.0 -0.25 -0.3612 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G21 compound treatment 604070.0 120000.0 0.68 324130.0 -85000.0 -0.49 0.1298 0.1551 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G22 compound treatment 463010.0 -20900.0 -0.12 231130.0 -178000.0 -1.03 -0.8131 -0.7826 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G23 compound treatment 441130.0 -42800.0 -0.24 300340.0 -109000.0 -0.63 -0.6164 -0.9128 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 G24 compound treatment 497360.0 13500.0 0.08 303490.0 -106000.0 -0.61 -0.3796 -0.615 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H01 compound treatment 342740.0 -141000.0 -0.79 519950.0 111000.0 0.64 -0.1074 -0.1051 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H02 compound treatment 609280.0 125000.0 0.71 333000.0 -76100.0 -0.44 0.1869 0.2245 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H03 mock treatment 570240.0 86300.0 0.49 447570.0 38500.0 0.22 0.5013 0.9376 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H04 mock treatment 282940.0 -201000.0 -1.13 519840.0 111000.0 0.64 -0.3459 -0.2659 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H05 compound treatment 209030.0 -275000.0 -1.55 273670.0 -135000.0 -0.79 -1.6496 -0.9506 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H06 compound treatment 361880.0 -122000.0 -0.69 288240.0 -121000.0 -0.7 -0.9815 -0.9999 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H07 compound treatment 416490.0 -67400.0 -0.38 405820.0 -3300.0 -0.02 -0.2819 -0.7418 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H08 compound treatment 469560.0 -14300.0 -0.08 443840.0 34700.0 0.2 0.0853 0.393 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H09 compound treatment 495010.0 11100.0 0.06 285480.0 -124000.0 -0.72 -0.4628 -0.643 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H10 compound treatment 368100.0 -116000.0 -0.65 187770.0 -221000.0 -1.28 -1.3687 -0.9507 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H11 compound treatment 331070.0 -153000.0 -0.86 250340.0 -159000.0 -0.92 -1.2595 -0.9994 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H12 compound treatment 551680.0 67800.0 0.38 333300.0 -75800.0 -0.44 -0.0411 -0.0707 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H13 compound treatment 195070.0 -289000.0 -1.63 211150.0 -198000.0 -1.15 -1.9616 -0.9855 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H14 compound treatment 474460.0 -9450.0 -0.05 257030.0 -152000.0 -0.88 -0.6613 -0.7484 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H15 compound treatment 346350.0 -138000.0 -0.77 286960.0 -122000.0 -0.71 -1.0485 -0.999 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H16 compound treatment 264000.0 -220000.0 -1.24 135690.0 -273000.0 -1.59 -1.9967 -0.9925 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H17 compound treatment 520670.0 36800.0 0.21 464220.0 55100.0 0.32 0.3723 0.9779 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H18 compound treatment 262780.0 -221000.0 -1.24 286090.0 -123000.0 -0.71 -1.3848 -0.9651 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H19 mock treatment 420220.0 -63700.0 -0.36 320450.0 -88700.0 -0.51 -0.6171 -0.9845 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H20 mock treatment 531210.0 47300.0 0.27 410910.0 1790.0 0.01 0.1956 0.7342 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H21 compound treatment 232980.0 -251000.0 -1.41 250880.0 -158000.0 -0.92 -1.6478 -0.9782 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H22 compound treatment 29240.0 -455000.0 -2.56 22270.0 -387000.0 -2.24 -3.3963 -0.9978 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H23 compound treatment 19520.0 -464000.0 -2.61 12040.0 -397000.0 -2.3 -3.4769 -0.998 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 H24 compound treatment 302720.0 -181000.0 -1.02 270590.0 -139000.0 -0.8 -1.2893 -0.993 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I01 compound treatment 437890.0 -46000.0 -0.26 421510.0 12400.0 0.07 -0.1324 -0.4923 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I02 compound treatment 456640.0 -27300.0 -0.15 363220.0 -45900.0 -0.27 -0.2968 -0.9658 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I03 compound treatment 497370.0 13500.0 0.08 333290.0 -75800.0 -0.44 -0.2574 -0.5768 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I04 compound treatment 438760.0 -45100.0 -0.25 403050.0 -6070.0 -0.04 -0.2046 -0.7974 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I05 mock treatment 442910.0 -41000.0 -0.23 291840.0 -117000.0 -0.68 -0.6441 -0.8968 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I06 mock treatment 616110.0 132000.0 0.74 444980.0 35900.0 0.21 0.6733 0.8713 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I07 compound treatment 305450.0 -178000.0 -1.0 373390.0 -35700.0 -0.21 -0.8569 -0.8354 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I08 compound treatment 393300.0 -90600.0 -0.51 249810.0 -159000.0 -0.92 -1.014 -0.9608 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I09 compound treatment 351390.0 -133000.0 -0.75 396030.0 -13100.0 -0.08 -0.5812 -0.775 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I10 compound treatment 325350.0 -159000.0 -0.89 183210.0 -226000.0 -1.31 -1.5576 -0.9825 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I11 compound treatment 318890.0 -165000.0 -0.93 432730.0 23600.0 0.14 -0.5601 -0.5964 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I12 compound treatment 536170.0 52300.0 0.29 421640.0 12500.0 0.07 0.2594 0.856 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I13 compound treatment 394280.0 -89600.0 -0.5 451140.0 42000.0 0.24 -0.1845 -0.3292 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I14 compound treatment 481360.0 -2550.0 -0.01 518130.0 109000.0 0.63 0.4369 0.6909 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I15 compound treatment 370620.0 -113000.0 -0.64 273770.0 -135000.0 -0.78 -1.006 -0.9947 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I16 compound treatment 546680.0 62800.0 0.35 465040.0 55900.0 0.32 0.4792 0.9991 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I17 compound treatment 372280.0 -112000.0 -0.63 270960.0 -138000.0 -0.8 -1.0109 -0.9928 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I18 compound treatment 573200.0 89300.0 0.5 448370.0 39300.0 0.23 0.5164 0.9358 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I19 compound treatment 575520.0 91600.0 0.52 438490.0 29400.0 0.17 0.4851 0.8932 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I20 compound treatment 555440.0 71500.0 0.4 284650.0 -124000.0 -0.72 -0.2257 -0.273 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I21 mock treatment 501040.0 17100.0 0.1 408530.0 -587.0 0.0 0.0658 0.6817 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I22 mock treatment 429850.0 -54100.0 -0.3 429620.0 20500.0 0.12 -0.1311 -0.4013 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I23 compound treatment 321450.0 -162000.0 -0.91 329780.0 -79300.0 -0.46 -0.972 -0.9495 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 I24 compound treatment 405840.0 -78100.0 -0.44 393640.0 -15500.0 -0.09 -0.3742 -0.8343 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J01 compound treatment 519540.0 35600.0 0.2 466750.0 57600.0 0.33 0.3782 0.9702 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J02 compound treatment 316960.0 -167000.0 -0.94 342790.0 -66300.0 -0.38 -0.9366 -0.9223 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J03 compound treatment 408440.0 -75500.0 -0.42 304550.0 -105000.0 -0.61 -0.7292 -0.9849 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J04 compound treatment 403840.0 -80100.0 -0.45 200080.0 -209000.0 -1.21 -1.176 -0.9092 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J05 mock treatment 505980.0 22100.0 0.12 493790.0 84700.0 0.49 0.4351 0.859 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J06 mock treatment 586370.0 102000.0 0.58 258960.0 -150000.0 -0.87 -0.2079 -0.199 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J07 compound treatment 533870.0 50000.0 0.28 270240.0 -139000.0 -0.81 -0.3706 -0.4345 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J08 compound treatment 121930.0 -362000.0 -2.04 89600.0 -320000.0 -1.85 -2.7512 -0.9989 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J09 compound treatment 423010.0 -60900.0 -0.34 327640.0 -81500.0 -0.47 -0.5765 -0.9876 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J10 compound treatment 136320.0 -348000.0 -1.96 90960.0 -318000.0 -1.85 -2.6883 -0.9996 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J11 compound treatment 366670.0 -117000.0 -0.66 300890.0 -108000.0 -0.63 -0.9105 -0.9997 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J12 compound treatment 402280.0 -81600.0 -0.46 220420.0 -189000.0 -1.09 -1.0988 -0.9257 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J13 compound treatment 205300.0 -279000.0 -1.57 306100.0 -103000.0 -0.6 -1.5315 -0.9125 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J14 compound treatment 445940.0 -38000.0 -0.21 329020.0 -80100.0 -0.46 -0.4796 -0.9379 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J15 compound treatment 381320.0 -103000.0 -0.58 298740.0 -110000.0 -0.64 -0.861 -0.9987 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J16 compound treatment 361650.0 -122000.0 -0.69 307000.0 -102000.0 -0.59 -0.9054 -0.9972 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J17 compound treatment 436960.0 -46900.0 -0.26 222950.0 -186000.0 -1.08 -0.9503 -0.855 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J18 compound treatment 497730.0 13800.0 0.08 406890.0 -2230.0 -0.01 0.0459 0.5818 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J19 compound treatment 464280.0 -19600.0 -0.11 339590.0 -69500.0 -0.4 -0.3633 -0.8689 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J20 compound treatment 486250.0 2340.0 0.01 459320.0 50200.0 0.29 0.2152 0.7384 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J21 mock treatment 340370.0 -144000.0 -0.81 368760.0 -40400.0 -0.23 -0.7369 -0.8759 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J22 mock treatment 465410.0 -18500.0 -0.1 363800.0 -45300.0 -0.26 -0.2595 -0.9179 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J23 compound treatment 411620.0 -72300.0 -0.41 278880.0 -130000.0 -0.76 -0.8218 -0.9579 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 J24 compound treatment 477250.0 -6660.0 -0.04 269600.0 -140000.0 -0.81 -0.5986 -0.7391 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K01 compound treatment 429880.0 -54000.0 -0.3 448030.0 38900.0 0.23 -0.0555 -0.1465 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K02 compound treatment 600670.0 117000.0 0.66 434150.0 25000.0 0.15 0.5674 0.843 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K03 compound treatment 210810.0 -273000.0 -1.54 294180.0 -115000.0 -0.67 -1.5585 -0.93 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K04 compound treatment 229390.0 -255000.0 -1.43 414480.0 5360.0 0.03 -0.9912 -0.6916 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K05 compound treatment 381120.0 -103000.0 -0.58 431450.0 22300.0 0.13 -0.3176 -0.5356 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K06 compound treatment 293830.0 -190000.0 -1.07 493210.0 84100.0 0.49 -0.4118 -0.3502 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K07 mock treatment 341630.0 -142000.0 -0.8 465040.0 55900.0 0.32 -0.337 -0.39 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K08 mock treatment 359260.0 -125000.0 -0.7 382560.0 -26600.0 -0.15 -0.6051 -0.8423 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K09 compound treatment 242250.0 -242000.0 -1.36 208810.0 -200000.0 -1.16 -1.7834 -0.9969 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K10 compound treatment 200750.0 -283000.0 -1.59 331300.0 -77800.0 -0.45 -1.4463 -0.873 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K11 compound treatment 126020.0 -358000.0 -2.01 145820.0 -263000.0 -1.53 -2.5044 -0.9906 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K12 compound treatment 601570.0 118000.0 0.66 295700.0 -113000.0 -0.66 0.0033 0.0035 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K13 compound treatment 383050.0 -101000.0 -0.57 316680.0 -92400.0 -0.54 -0.7806 -0.9996 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K14 compound treatment 452480.0 -31400.0 -0.18 375310.0 -33800.0 -0.2 -0.2637 -0.9987 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K15 mock treatment 553720.0 69800.0 0.39 477370.0 68300.0 0.4 0.5578 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K16 mock treatment 513150.0 29200.0 0.16 458340.0 49200.0 0.29 0.3183 0.9658 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K17 compound treatment 354670.0 -129000.0 -0.73 335560.0 -73600.0 -0.43 -0.8161 -0.9676 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K18 compound treatment 603710.0 120000.0 0.67 514880.0 106000.0 0.61 0.9106 0.9989 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K19 compound treatment 487520.0 3610.0 0.02 262920.0 -146000.0 -0.85 -0.5852 -0.69 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K20 compound treatment 499490.0 15600.0 0.09 514750.0 106000.0 0.61 0.4952 0.8002 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K21 compound treatment 384500.0 -99400.0 -0.56 393120.0 -16000.0 -0.09 -0.4613 -0.8132 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K22 compound treatment 504650.0 20700.0 0.12 493920.0 84800.0 0.49 0.4303 0.8513 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K23 mock treatment 494800.0 10900.0 0.06 315420.0 -93700.0 -0.54 -0.3409 -0.6234 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 K24 mock treatment 551640.0 67700.0 0.38 444670.0 35600.0 0.21 0.4154 0.9583 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L01 compound treatment 368570.0 -115000.0 -0.65 424180.0 15100.0 0.09 -0.3974 -0.6065 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L02 compound treatment 471450.0 -12500.0 -0.07 489190.0 80100.0 0.46 0.2788 0.5936 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L03 compound treatment 145240.0 -339000.0 -1.91 208640.0 -200000.0 -1.16 -2.1703 -0.9719 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L04 compound treatment 41680.0 -442000.0 -2.49 30100.0 -379000.0 -2.2 -3.3146 -0.9981 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L05 compound treatment 322990.0 -161000.0 -0.91 103580.0 -306000.0 -1.77 -1.8935 -0.9515 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L06 compound treatment 275010.0 -209000.0 -1.18 354240.0 -54900.0 -0.32 -1.0566 -0.8673 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L07 mock treatment 404580.0 -79300.0 -0.45 441250.0 32100.0 0.19 -0.184 -0.3803 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L08 mock treatment 407790.0 -76100.0 -0.43 395450.0 -13700.0 -0.08 -0.3591 -0.8239 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L09 compound treatment 373960.0 -110000.0 -0.62 429570.0 20500.0 0.12 -0.3538 -0.5614 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L10 compound treatment 82750.0 -401000.0 -2.26 81940.0 -327000.0 -1.9 -2.9386 -0.9963 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L11 compound treatment 502290.0 18400.0 0.1 440860.0 31700.0 0.18 0.2033 0.9629 1006359 PK04_181227 Cc1cccc[n+]1C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L12 compound treatment 401760.0 -82100.0 -0.46 218750.0 -190000.0 -1.1 -1.1077 -0.9254 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L13 compound treatment 491740.0 7830.0 0.04 399710.0 -9410.0 -0.05 -0.0074 -0.1056 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L14 compound treatment 492850.0 8940.0 0.05 388830.0 -20300.0 -0.12 -0.0476 -0.372 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L15 mock treatment 571040.0 87100.0 0.49 329810.0 -79300.0 -0.46 0.0216 0.0321 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L16 mock treatment 540720.0 56800.0 0.32 287100.0 -122000.0 -0.71 -0.2742 -0.3531 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L17 compound treatment 437780.0 -46100.0 -0.26 302130.0 -107000.0 -0.62 -0.6224 -0.9253 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L18 compound treatment 384770.0 -99100.0 -0.56 446800.0 37700.0 0.22 -0.2401 -0.4006 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L19 compound treatment 494940.0 11000.0 0.06 393120.0 -16000.0 -0.09 -0.0217 -0.1943 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L20 compound treatment 219000.0 -265000.0 -1.49 235400.0 -174000.0 -1.01 -1.7669 -0.9818 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L21 compound treatment 511840.0 27900.0 0.16 348160.0 -61000.0 -0.35 -0.1388 -0.3587 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L22 compound treatment 80180.0 -404000.0 -2.27 85300.0 -324000.0 -1.88 -2.935 -0.9955 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L23 mock treatment 477540.0 -6370.0 -0.04 438510.0 29400.0 0.17 0.0952 0.5464 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 L24 mock treatment 529080.0 45200.0 0.25 363680.0 -45400.0 -0.26 -0.0065 -0.0178 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M01 compound treatment 163050.0 -321000.0 -1.81 173920.0 -235000.0 -1.36 -2.2417 -0.9904 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M02 compound treatment 156760.0 -327000.0 -1.84 171770.0 -237000.0 -1.38 -2.2756 -0.9897 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M03 compound treatment 308450.0 -175000.0 -0.99 228370.0 -181000.0 -1.05 -1.4397 -0.9996 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M04 compound treatment 18910.0 -465000.0 -2.62 22050.0 -387000.0 -2.24 -3.4383 -0.9971 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M05 compound treatment 179380.0 -305000.0 -1.71 104340.0 -305000.0 -1.77 -2.4621 -0.9999 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M06 compound treatment 566100.0 82200.0 0.46 332980.0 -76100.0 -0.44 0.015 0.0234 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M07 compound treatment 416480.0 -67400.0 -0.38 209380.0 -200000.0 -1.16 -1.0875 -0.8921 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M08 compound treatment 290890.0 -193000.0 -1.09 259200.0 -150000.0 -0.87 -1.3831 -0.9939 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M09 mock treatment 532440.0 48500.0 0.27 442910.0 33800.0 0.2 0.3318 0.9867 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M10 mock treatment 424800.0 -59100.0 -0.33 491360.0 82200.0 0.48 0.102 0.1753 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M11 compound treatment 227270.0 -257000.0 -1.44 223520.0 -186000.0 -1.08 -1.7827 -0.9895 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M12 compound treatment 531380.0 47500.0 0.27 419810.0 10700.0 0.06 0.2328 0.8486 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M13 mock treatment 275760.0 -208000.0 -1.17 376600.0 -32500.0 -0.19 -0.9619 -0.8105 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M14 mock treatment 637810.0 154000.0 0.87 374480.0 -34600.0 -0.2 0.4706 0.5291 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M15 compound treatment 291780.0 -192000.0 -1.08 219080.0 -190000.0 -1.1 -1.5441 -1.0 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M16 compound treatment 44190.0 -440000.0 -2.48 35890.0 -373000.0 -2.16 -3.2809 -0.9978 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M17 compound treatment 236550.0 -247000.0 -1.39 208320.0 -201000.0 -1.16 -1.8081 -0.996 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M18 compound treatment 495860.0 12000.0 0.07 248690.0 -160000.0 -0.93 -0.6103 -0.6543 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M19 compound treatment 262490.0 -221000.0 -1.25 285720.0 -123000.0 -0.72 -1.3874 -0.9653 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M20 compound treatment 232570.0 -251000.0 -1.41 160420.0 -249000.0 -1.44 -2.0204 -1.0 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M21 compound treatment 349790.0 -134000.0 -0.76 327720.0 -81400.0 -0.47 -0.8677 -0.9744 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M22 compound treatment 425880.0 -58000.0 -0.33 390560.0 -18600.0 -0.11 -0.3071 -0.8929 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M23 compound treatment 188010.0 -296000.0 -1.67 164730.0 -244000.0 -1.42 -2.1801 -0.9968 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 M24 compound treatment 521830.0 37900.0 0.21 326020.0 -83100.0 -0.48 -0.1898 -0.3601 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N01 compound treatment 523590.0 39700.0 0.22 449920.0 40800.0 0.24 0.3253 0.9996 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N02 compound treatment 528710.0 44800.0 0.25 280350.0 -129000.0 -0.75 -0.3497 -0.4437 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N03 compound treatment 286360.0 -198000.0 -1.11 343320.0 -65800.0 -0.38 -1.0562 -0.8983 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N04 compound treatment 454970.0 -28900.0 -0.16 271040.0 -138000.0 -0.8 -0.6814 -0.8339 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N05 compound treatment 428290.0 -55600.0 -0.31 383080.0 -26000.0 -0.15 -0.3282 -0.9441 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N06 compound treatment 514360.0 30500.0 0.17 396160.0 -13000.0 -0.08 0.0681 0.3637 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N07 compound treatment 275540.0 -208000.0 -1.17 219390.0 -190000.0 -1.1 -1.6075 -0.9995 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N08 compound treatment 523580.0 39700.0 0.22 439550.0 30400.0 0.18 0.2827 0.9932 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N09 mock treatment 440910.0 -43000.0 -0.24 468160.0 59000.0 0.34 0.071 0.1692 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N10 mock treatment 421310.0 -62600.0 -0.35 450980.0 41900.0 0.24 -0.0775 -0.1811 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N11 compound treatment 433980.0 -49900.0 -0.28 325220.0 -83900.0 -0.49 -0.5428 -0.966 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N12 compound treatment 433650.0 -50300.0 -0.28 518730.0 110000.0 0.64 0.2494 0.3585 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N13 mock treatment 619930.0 136000.0 0.77 518850.0 110000.0 0.64 0.9914 0.9958 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N14 mock treatment 583910.0 100000.0 0.56 489280.0 80200.0 0.46 0.7268 0.9955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N15 compound treatment 515800.0 31900.0 0.18 484110.0 75000.0 0.43 0.4345 0.9234 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N16 compound treatment 549280.0 65400.0 0.37 489600.0 80500.0 0.47 0.5903 0.9931 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N17 compound treatment 500410.0 16500.0 0.09 270350.0 -139000.0 -0.8 -0.5034 -0.6214 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N18 compound treatment 439710.0 -44200.0 -0.25 382850.0 -26300.0 -0.15 -0.2837 -0.9723 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N19 compound treatment 456390.0 -27500.0 -0.15 369600.0 -39500.0 -0.23 -0.2716 -0.9818 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N20 compound treatment 191010.0 -293000.0 -1.65 152050.0 -257000.0 -1.49 -2.2201 -0.9987 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N21 compound treatment 339520.0 -144000.0 -0.81 228340.0 -181000.0 -1.05 -1.3161 -0.9921 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N22 compound treatment 536700.0 52800.0 0.3 412160.0 3040.0 0.02 0.2226 0.7478 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N23 compound treatment 411360.0 -72500.0 -0.41 391770.0 -17300.0 -0.1 -0.3599 -0.8557 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 N24 compound treatment 537790.0 53900.0 0.3 290610.0 -119000.0 -0.69 -0.2715 -0.3614 1004341 PK04_181276 c1ccc2cnccc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O01 compound treatment 381180.0 -103000.0 -0.58 435090.0 26000.0 0.15 -0.3024 -0.5061 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O02 compound treatment 168190.0 -316000.0 -1.78 154090.0 -255000.0 -1.48 -2.3026 -0.9958 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O03 compound treatment 172880.0 -311000.0 -1.75 427850.0 18700.0 0.11 -1.1613 -0.662 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O04 compound treatment 112840.0 -371000.0 -2.09 81290.0 -328000.0 -1.9 -2.8215 -0.9989 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O05 compound treatment 439870.0 -44000.0 -0.25 487920.0 78800.0 0.46 0.1478 0.2844 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O06 compound treatment 128050.0 -356000.0 -2.0 168270.0 -241000.0 -1.4 -2.4042 -0.9845 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O07 compound treatment 88500.0 -395000.0 -2.23 73330.0 -336000.0 -1.95 -2.951 -0.9978 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O08 compound treatment 112000.0 -372000.0 -2.09 122130.0 -287000.0 -1.66 -2.6573 -0.9935 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O09 compound treatment 205960.0 -278000.0 -1.56 145700.0 -263000.0 -1.53 -2.1866 -0.9999 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O10 compound treatment 361930.0 -122000.0 -0.69 361920.0 -47200.0 -0.27 -0.6791 -0.9187 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O11 mock treatment 514410.0 30500.0 0.17 405410.0 -3710.0 -0.02 0.1062 0.6138 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O12 mock treatment 570000.0 86100.0 0.48 454960.0 45800.0 0.27 0.5307 0.96 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O13 compound treatment 375680.0 -108000.0 -0.61 510260.0 101000.0 0.59 -0.0161 -0.019 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O14 compound treatment 509760.0 25900.0 0.15 414130.0 5010.0 0.03 0.1235 0.8319 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O15 compound treatment 422730.0 -61200.0 -0.34 351680.0 -57400.0 -0.33 -0.4791 -0.9999 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O16 compound treatment 421030.0 -62900.0 -0.35 466110.0 57000.0 0.33 -0.0166 -0.0342 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O17 compound treatment 459110.0 -24800.0 -0.14 452420.0 43300.0 0.25 0.0789 0.2745 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O18 compound treatment 568020.0 84100.0 0.47 340010.0 -69100.0 -0.4 0.0514 0.0829 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O19 compound treatment 359100.0 -125000.0 -0.7 353520.0 -55600.0 -0.32 -0.7248 -0.9376 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O20 compound treatment 491840.0 7930.0 0.04 365800.0 -43300.0 -0.25 -0.1461 -0.5725 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O21 compound treatment 334810.0 -149000.0 -0.84 353400.0 -55700.0 -0.32 -0.822 -0.9139 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O22 compound treatment 541090.0 57200.0 0.32 436210.0 27100.0 0.16 0.3387 0.9456 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O23 compound treatment 587100.0 103000.0 0.58 425160.0 16000.0 0.09 0.4766 0.81 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 O24 compound treatment 459170.0 -24700.0 -0.14 284660.0 -124000.0 -0.72 -0.6089 -0.8283 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P01 compound treatment 163810.0 -320000.0 -1.8 253670.0 -155000.0 -0.9 -1.9117 -0.9488 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P02 compound treatment 441030.0 -42900.0 -0.24 411880.0 2760.0 0.02 -0.1594 -0.6587 1015751 PK04_181300 Cc1ccncc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P03 compound treatment 323560.0 -160000.0 -0.9 268210.0 -141000.0 -0.82 -1.2161 -0.9988 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P04 compound treatment 534320.0 50400.0 0.28 305800.0 -103000.0 -0.6 -0.223 -0.3364 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P05 compound treatment 421800.0 -62100.0 -0.35 186270.0 -223000.0 -1.29 -1.1611 -0.8672 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P06 compound treatment 390720.0 -93200.0 -0.52 266770.0 -142000.0 -0.83 -0.9547 -0.9761 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P07 compound treatment 243200.0 -241000.0 -1.36 97950.0 -311000.0 -1.8 -2.2342 -0.99 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P08 compound treatment 305990.0 -178000.0 -1.0 392040.0 -17100.0 -0.1 -0.7783 -0.7733 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P09 compound treatment 356640.0 -127000.0 -0.72 236920.0 -172000.0 -1.0 -1.2128 -0.9867 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P10 compound treatment 376040.0 -108000.0 -0.61 395440.0 -13700.0 -0.08 -0.4855 -0.7927 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P11 mock treatment 445780.0 -38100.0 -0.21 376030.0 -33100.0 -0.19 -0.2875 -0.9984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P12 mock treatment 408000.0 -75900.0 -0.43 364420.0 -44700.0 -0.26 -0.4855 -0.9713 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P13 compound treatment 247740.0 -236000.0 -1.33 330420.0 -78700.0 -0.46 -1.2628 -0.8984 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P14 compound treatment 444800.0 -39100.0 -0.22 417830.0 8710.0 0.05 -0.12 -0.531 1009497 PK04_181310 Cc1cc[n+](C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P15 compound treatment 291310.0 -193000.0 -1.08 288960.0 -120000.0 -0.7 -1.2594 -0.9772 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P16 compound treatment 382720.0 -101000.0 -0.57 324170.0 -84900.0 -0.49 -0.7512 -0.9974 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P17 compound treatment 202620.0 -281000.0 -1.58 207070.0 -202000.0 -1.17 -1.9483 -0.989 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P18 compound treatment 434300.0 -49600.0 -0.28 368430.0 -40700.0 -0.24 -0.3643 -0.9965 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P19 compound treatment 319060.0 -165000.0 -0.93 276230.0 -133000.0 -0.77 -1.2012 -0.9957 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P20 compound treatment 393730.0 -90200.0 -0.51 363880.0 -45200.0 -0.26 -0.5445 -0.9528 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P21 compound treatment 272210.0 -212000.0 -1.19 258930.0 -150000.0 -0.87 -1.4586 -0.9881 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P22 compound treatment 402100.0 -81800.0 -0.46 297500.0 -112000.0 -0.65 -0.7834 -0.9861 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P23 compound treatment 424270.0 -59600.0 -0.34 327380.0 -81700.0 -0.47 -0.5726 -0.9857 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2181 P24 compound treatment 351040.0 -133000.0 -0.75 165920.0 -243000.0 -1.41 -1.5262 -0.956 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A01 compound treatment 116890.0 -321000.0 -1.81 323810.0 -22800.0 -0.13 -1.3717 -0.7569 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A02 compound treatment 158400.0 -280000.0 -1.57 150010.0 -197000.0 -1.14 -1.9191 -0.9875 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A03 compound treatment 196390.0 -242000.0 -1.36 230250.0 -116000.0 -0.68 -1.4389 -0.9478 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A04 compound treatment 307210.0 -131000.0 -0.74 290010.0 -56600.0 -0.33 -0.7527 -0.9339 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A05 compound treatment 189600.0 -248000.0 -1.4 151330.0 -195000.0 -1.13 -1.7895 -0.9945 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A06 compound treatment 114810.0 -323000.0 -1.82 149010.0 -198000.0 -1.15 -2.0968 -0.9752 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A07 compound treatment 209920.0 -228000.0 -1.28 532800.0 186000.0 1.08 -0.1443 -0.086 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A08 compound treatment 229770.0 -208000.0 -1.17 289620.0 -57000.0 -0.33 -1.0625 -0.8726 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A09 compound treatment 205510.0 -232000.0 -1.31 389200.0 42600.0 0.25 -0.7507 -0.5638 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A10 compound treatment 213710.0 -224000.0 -1.26 251450.0 -95200.0 -0.55 -1.283 -0.9312 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A11 compound treatment 174500.0 -263000.0 -1.48 525130.0 178000.0 1.04 -0.3168 -0.1751 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A12 compound treatment 177970.0 -260000.0 -1.46 273080.0 -73600.0 -0.43 -1.3366 -0.8767 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A13 mock treatment 196360.0 -242000.0 -1.36 195360.0 -151000.0 -0.88 -1.5821 -0.9775 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A14 mock treatment 211000.0 -227000.0 -1.28 206240.0 -140000.0 -0.81 -1.4792 -0.9763 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A15 compound treatment 223910.0 -214000.0 -1.2 244000.0 -103000.0 -0.6 -1.2729 -0.9472 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A16 compound treatment 538340.0 100000.0 0.57 313060.0 -33600.0 -0.19 0.2619 0.4381 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A17 compound treatment 505400.0 67500.0 0.38 432320.0 85700.0 0.5 0.6198 0.9912 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A18 compound treatment 280640.0 -157000.0 -0.89 348880.0 2240.0 0.01 -0.617 -0.6967 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A19 compound treatment 241120.0 -197000.0 -1.11 226660.0 -120000.0 -0.7 -1.2755 -0.9749 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A20 compound treatment 317800.0 -120000.0 -0.68 320440.0 -26200.0 -0.15 -0.5857 -0.8449 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A21 compound treatment 468110.0 30200.0 0.17 418890.0 72200.0 0.42 0.4163 0.9209 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A22 compound treatment 357140.0 -80800.0 -0.45 262460.0 -84200.0 -0.49 -0.6669 -0.9994 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A23 compound treatment 280910.0 -157000.0 -0.88 257450.0 -89200.0 -0.52 -0.9909 -0.9674 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 A24 compound treatment 230560.0 -207000.0 -1.17 333560.0 -13100.0 -0.08 -0.8792 -0.7515 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B01 compound treatment 529990.0 92000.0 0.52 559690.0 213000.0 1.24 1.2401 0.9255 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B02 compound treatment 381150.0 -56800.0 -0.32 184520.0 -162000.0 -0.94 -0.8909 -0.8971 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B03 compound treatment 280550.0 -157000.0 -0.89 389220.0 42600.0 0.25 -0.452 -0.4913 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B04 compound treatment 412890.0 -25100.0 -0.14 324010.0 -22600.0 -0.13 -0.1926 -0.9994 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B05 compound treatment 264610.0 -173000.0 -0.98 390100.0 43500.0 0.25 -0.5118 -0.5078 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B06 compound treatment 205440.0 -233000.0 -1.31 416190.0 69500.0 0.4 -0.6403 -0.4675 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B07 compound treatment 570940.0 133000.0 0.75 257530.0 -89100.0 -0.52 0.164 0.1802 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B08 compound treatment 586810.0 149000.0 0.84 564100.0 217000.0 1.26 1.4843 0.9803 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B09 compound treatment 341600.0 -96300.0 -0.54 325980.0 -20700.0 -0.12 -0.4683 -0.843 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B10 compound treatment 387210.0 -50700.0 -0.29 500830.0 154000.0 0.89 0.4303 0.4584 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B11 compound treatment 338000.0 -99900.0 -0.56 231520.0 -115000.0 -0.67 -0.87 -0.9964 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B12 compound treatment 339430.0 -98500.0 -0.55 371910.0 25300.0 0.15 -0.2886 -0.503 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B13 mock treatment 409040.0 -28900.0 -0.16 553700.0 207000.0 1.2 0.734 0.6057 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B14 mock treatment 323040.0 -115000.0 -0.65 366240.0 19600.0 0.11 -0.377 -0.5741 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B15 compound treatment 487900.0 50000.0 0.28 604420.0 258000.0 1.49 1.2559 0.8256 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B16 compound treatment 265360.0 -173000.0 -0.97 235780.0 -111000.0 -0.64 -1.1416 -0.9799 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B17 compound treatment 460900.0 23000.0 0.13 536700.0 190000.0 1.1 0.8708 0.7846 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B18 compound treatment 482820.0 44900.0 0.25 492870.0 146000.0 0.85 0.7783 0.8795 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B19 compound treatment 390770.0 -47200.0 -0.27 451070.0 104000.0 0.61 0.2404 0.3636 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B20 compound treatment 289380.0 -149000.0 -0.84 517280.0 171000.0 0.99 0.1083 0.0836 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B21 compound treatment 371380.0 -66600.0 -0.37 555260.0 209000.0 1.21 0.5905 0.4662 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B22 compound treatment 529640.0 91700.0 0.52 319520.0 -27100.0 -0.16 0.2538 0.4703 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B23 compound treatment 446100.0 8150.0 0.05 364530.0 17900.0 0.1 0.1058 0.9327 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 B24 compound treatment 366490.0 -71500.0 -0.4 438890.0 92200.0 0.53 0.0938 0.1402 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C01 compound treatment 388660.0 -49300.0 -0.28 504740.0 158000.0 0.92 0.4521 0.472 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C02 compound treatment 196680.0 -241000.0 -1.36 438080.0 91400.0 0.53 -0.5854 -0.4015 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C03 compound treatment 244710.0 -193000.0 -1.09 297930.0 -48700.0 -0.28 -0.969 -0.8621 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C04 compound treatment 210240.0 -228000.0 -1.28 376440.0 29800.0 0.17 -0.7842 -0.6063 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C05 compound treatment 431710.0 -6240.0 -0.04 208480.0 -138000.0 -0.8 -0.5914 -0.7374 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C06 compound treatment 276520.0 -161000.0 -0.91 200050.0 -147000.0 -0.85 -1.2437 -0.9994 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C07 compound treatment 394650.0 -43300.0 -0.24 249330.0 -97300.0 -0.56 -0.5714 -0.9295 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C08 compound treatment 457120.0 19200.0 0.11 356230.0 9590.0 0.06 0.1156 0.9524 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C09 compound treatment 441310.0 3360.0 0.02 466980.0 120000.0 0.7 0.5069 0.726 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C10 compound treatment 540930.0 103000.0 0.58 185160.0 -161000.0 -0.94 -0.2523 -0.229 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C11 mock treatment 587330.0 149000.0 0.84 256130.0 -90500.0 -0.52 0.2235 0.2254 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C12 mock treatment 484880.0 46900.0 0.26 221210.0 -125000.0 -0.73 -0.3276 -0.4232 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C13 compound treatment 255630.0 -182000.0 -1.03 240320.0 -106000.0 -0.62 -1.1618 -0.9703 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C14 compound treatment 397940.0 -40000.0 -0.23 510450.0 164000.0 0.95 0.5125 0.5249 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C15 mock treatment 249660.0 -188000.0 -1.06 503600.0 157000.0 0.91 -0.1059 -0.0758 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C16 mock treatment 379590.0 -58400.0 -0.33 453950.0 107000.0 0.62 0.2077 0.2952 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C17 compound treatment 419120.0 -18800.0 -0.11 346690.0 48.1 0.0 -0.0748 -0.7052 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C18 compound treatment 438840.0 891.0 0.01 223490.0 -123000.0 -0.71 -0.5015 -0.7021 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C19 compound treatment 142600.0 -295000.0 -1.66 70400.0 -276000.0 -1.6 -2.3085 -0.9998 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C20 compound treatment 440400.0 2450.0 0.01 153670.0 -193000.0 -1.12 -0.7816 -0.6983 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C21 compound treatment 566320.0 128000.0 0.72 304930.0 -41700.0 -0.24 0.3399 0.4461 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C22 compound treatment 508580.0 70600.0 0.4 315360.0 -31300.0 -0.18 0.1529 0.3498 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C23 compound treatment 279650.0 -158000.0 -0.89 247450.0 -99200.0 -0.58 -1.0369 -0.9776 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 C24 compound treatment 317340.0 -121000.0 -0.68 315630.0 -31000.0 -0.18 -0.6073 -0.8646 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D01 compound treatment 408070.0 -29900.0 -0.17 220850.0 -126000.0 -0.73 -0.6348 -0.8479 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D02 compound treatment 215140.0 -223000.0 -1.25 174560.0 -172000.0 -1.0 -1.5926 -0.9936 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D03 compound treatment 443040.0 5090.0 0.03 214000.0 -133000.0 -0.77 -0.5237 -0.6803 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D04 compound treatment 552360.0 114000.0 0.64 329130.0 -17500.0 -0.1 0.3836 0.5883 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D05 compound treatment 237090.0 -201000.0 -1.13 228290.0 -118000.0 -0.69 -1.2849 -0.9714 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D06 compound treatment 194090.0 -244000.0 -1.37 190320.0 -156000.0 -0.91 -1.6118 -0.9797 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D07 compound treatment 222590.0 -215000.0 -1.21 446530.0 99900.0 0.58 -0.4477 -0.3332 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D08 compound treatment 352220.0 -85700.0 -0.48 330530.0 -16100.0 -0.09 -0.4073 -0.8286 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D09 compound treatment 390010.0 -47900.0 -0.27 318940.0 -27700.0 -0.16 -0.3044 -0.9693 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D10 compound treatment 540100.0 102000.0 0.58 373170.0 26500.0 0.15 0.5154 0.8658 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D11 mock treatment 504720.0 66800.0 0.38 383230.0 36600.0 0.21 0.4158 0.9634 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D12 mock treatment 258170.0 -180000.0 -1.01 288890.0 -57800.0 -0.33 -0.9525 -0.8935 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D13 compound treatment 251810.0 -186000.0 -1.05 349180.0 2540.0 0.01 -0.7306 -0.6971 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D14 compound treatment 342010.0 -95900.0 -0.54 364010.0 17400.0 0.1 -0.3107 -0.5655 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D15 mock treatment 543170.0 105000.0 0.59 487910.0 141000.0 0.82 0.9982 0.9873 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D16 mock treatment 477010.0 39100.0 0.22 408240.0 61600.0 0.36 0.4081 0.9728 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D17 compound treatment 382210.0 -55700.0 -0.31 381210.0 34600.0 0.2 -0.0801 -0.2152 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D18 compound treatment 237200.0 -201000.0 -1.13 334300.0 -12300.0 -0.07 -0.8497 -0.7504 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D19 compound treatment 416400.0 -21500.0 -0.12 321570.0 -25100.0 -0.15 -0.1886 -0.9959 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D20 compound treatment 325040.0 -113000.0 -0.64 461570.0 115000.0 0.67 0.0218 0.0237 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D21 compound treatment 325410.0 -113000.0 -0.63 311790.0 -34900.0 -0.2 -0.5909 -0.8886 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D22 compound treatment 439680.0 1730.0 0.01 350490.0 3850.0 0.02 0.0227 0.931 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D23 compound treatment 388800.0 -49100.0 -0.28 257650.0 -89000.0 -0.52 -0.5606 -0.9573 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 D24 compound treatment 478370.0 40400.0 0.23 507200.0 161000.0 0.93 0.8193 0.8548 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E01 mock treatment 404660.0 -33300.0 -0.19 202690.0 -144000.0 -0.83 -0.7228 -0.8448 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E02 mock treatment 492760.0 54800.0 0.31 423270.0 76600.0 0.44 0.5324 0.9841 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E03 mock treatment 397330.0 -40600.0 -0.23 326290.0 -20400.0 -0.12 -0.2452 -0.9527 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E04 compound treatment 126960.0 -311000.0 -1.75 439680.0 93000.0 0.54 -0.8564 -0.4675 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E05 compound treatment 401320.0 -36600.0 -0.21 256000.0 -90600.0 -0.53 -0.5175 -0.9165 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E06 compound treatment 239420.0 -199000.0 -1.12 331470.0 -15200.0 -0.09 -0.8525 -0.7604 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E07 compound treatment 439430.0 1480.0 0.01 419200.0 72600.0 0.42 0.3034 0.721 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E08 compound treatment 361320.0 -76600.0 -0.43 318750.0 -27900.0 -0.16 -0.4194 -0.9104 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E09 mock treatment 377980.0 -60000.0 -0.34 332370.0 -14300.0 -0.08 -0.2972 -0.8551 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E10 mock treatment 510500.0 72600.0 0.41 566340.0 220000.0 1.27 1.1897 0.8892 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E11 compound treatment 505860.0 67900.0 0.38 247730.0 -98900.0 -0.57 -0.1353 -0.1963 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E12 compound treatment 196270.0 -242000.0 -1.36 134640.0 -212000.0 -1.23 -1.8314 -0.9987 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E13 compound treatment 434820.0 -3130.0 -0.02 509210.0 163000.0 0.94 0.6542 0.6938 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E14 compound treatment 496640.0 58700.0 0.33 504440.0 158000.0 0.92 0.8807 0.9052 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E15 compound treatment 317440.0 -121000.0 -0.68 125950.0 -221000.0 -1.28 -1.3847 -0.9559 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E16 compound treatment 366830.0 -71100.0 -0.4 278660.0 -68000.0 -0.39 -0.5619 -1.0 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E17 mock treatment 422880.0 -15100.0 -0.08 550410.0 204000.0 1.18 0.7756 0.6547 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E18 mock treatment 327600.0 -110000.0 -0.62 532240.0 186000.0 1.08 0.3218 0.259 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E19 compound treatment 301130.0 -137000.0 -0.77 291590.0 -55100.0 -0.32 -0.7704 -0.924 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E20 compound treatment 367040.0 -70900.0 -0.4 468320.0 122000.0 0.71 0.2167 0.2673 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E21 compound treatment 427520.0 -10400.0 -0.06 264410.0 -82200.0 -0.48 -0.3787 -0.7882 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E22 compound treatment 369210.0 -68700.0 -0.39 285060.0 -61600.0 -0.36 -0.5262 -0.9992 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E23 compound treatment 339040.0 -98900.0 -0.56 271160.0 -75500.0 -0.44 -0.7033 -0.9929 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 E24 compound treatment 365650.0 -72300.0 -0.41 467210.0 121000.0 0.7 0.2066 0.2554 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F01 mock treatment 309290.0 -129000.0 -0.72 520010.0 173000.0 1.01 0.1988 0.1604 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F02 mock treatment 485180.0 47200.0 0.27 266120.0 -80500.0 -0.47 -0.1422 -0.2646 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F03 compound treatment 557640.0 120000.0 0.67 235380.0 -111000.0 -0.65 0.0202 0.0216 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F04 compound treatment 433780.0 -4170.0 -0.02 194690.0 -152000.0 -0.88 -0.6397 -0.7257 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F05 compound treatment 222370.0 -216000.0 -1.21 209350.0 -137000.0 -0.8 -1.4212 -0.9791 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F06 compound treatment 323100.0 -115000.0 -0.65 201340.0 -145000.0 -0.84 -1.053 -0.9914 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F07 compound treatment 480480.0 42500.0 0.24 279430.0 -67200.0 -0.39 -0.1063 -0.2324 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F08 compound treatment 427090.0 -10900.0 -0.06 508800.0 162000.0 0.94 0.6218 0.6597 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F09 mock treatment 641670.0 204000.0 1.15 205790.0 -141000.0 -0.82 0.2333 0.1657 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F10 mock treatment 586080.0 148000.0 0.83 296860.0 -49800.0 -0.29 0.3855 0.4369 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F11 compound treatment 197120.0 -241000.0 -1.36 523720.0 177000.0 1.03 -0.2325 -0.1367 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F12 compound treatment 340590.0 -97400.0 -0.55 245870.0 -101000.0 -0.58 -0.8008 -0.9995 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F13 compound treatment 511710.0 73800.0 0.42 585190.0 239000.0 1.38 1.2719 0.8805 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F14 compound treatment 419200.0 -18700.0 -0.11 246270.0 -100000.0 -0.58 -0.4862 -0.8219 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F15 compound treatment 371520.0 -66400.0 -0.37 489760.0 143000.0 0.83 0.3225 0.3542 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F16 compound treatment 465720.0 27800.0 0.16 512040.0 165000.0 0.96 0.7888 0.8116 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F17 mock treatment 470020.0 32100.0 0.18 529300.0 183000.0 1.06 0.8767 0.8159 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F18 mock treatment 369230.0 -68700.0 -0.39 289920.0 -56700.0 -0.33 -0.5062 -0.9967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F19 compound treatment 477600.0 39700.0 0.22 276050.0 -70600.0 -0.41 -0.1316 -0.2823 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F20 compound treatment 291930.0 -146000.0 -0.82 216130.0 -131000.0 -0.76 -1.1165 -0.9992 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F21 compound treatment 435110.0 -2840.0 -0.02 239250.0 -107000.0 -0.62 -0.4517 -0.725 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F22 compound treatment 275930.0 -162000.0 -0.91 244010.0 -103000.0 -0.6 -1.0658 -0.9786 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F23 compound treatment 328080.0 -110000.0 -0.62 271200.0 -75400.0 -0.44 -0.7467 -0.9856 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 F24 compound treatment 327850.0 -110000.0 -0.62 361600.0 15000.0 0.09 -0.3769 -0.6023 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G01 compound treatment 454750.0 16800.0 0.09 531470.0 185000.0 1.07 0.8248 0.7665 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G02 compound treatment 563850.0 126000.0 0.71 593560.0 247000.0 1.43 1.5137 0.9474 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G03 mock treatment 341950.0 -96000.0 -0.54 404520.0 57900.0 0.34 -0.1448 -0.2276 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G04 mock treatment 369870.0 -68100.0 -0.38 374080.0 27400.0 0.16 -0.1585 -0.3819 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G05 compound treatment 358620.0 -79300.0 -0.45 272710.0 -73900.0 -0.43 -0.619 -0.9998 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G06 compound treatment 337760.0 -100000.0 -0.56 391930.0 45300.0 0.26 -0.2131 -0.3425 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G07 compound treatment 372030.0 -65900.0 -0.37 514210.0 168000.0 0.97 0.4248 0.4083 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G08 compound treatment 260770.0 -177000.0 -1.0 538030.0 191000.0 1.11 0.0796 0.0533 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G09 compound treatment 462570.0 24600.0 0.14 277020.0 -69600.0 -0.4 -0.1875 -0.4392 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G10 compound treatment 210110.0 -228000.0 -1.28 229540.0 -117000.0 -0.68 -1.3872 -0.9558 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G11 compound treatment 231300.0 -207000.0 -1.16 459270.0 113000.0 0.65 -0.3607 -0.2704 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G12 compound treatment 205530.0 -232000.0 -1.31 471270.0 125000.0 0.72 -0.4141 -0.277 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G13 compound treatment 545970.0 108000.0 0.61 178240.0 -168000.0 -0.98 -0.2606 -0.2265 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G14 compound treatment 496610.0 58700.0 0.33 216370.0 -130000.0 -0.76 -0.3007 -0.3647 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G15 compound treatment 252200.0 -186000.0 -1.05 279930.0 -66700.0 -0.39 -1.013 -0.9085 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G16 compound treatment 396810.0 -41100.0 -0.23 199620.0 -147000.0 -0.85 -0.7667 -0.8677 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G17 compound treatment 436870.0 -1080.0 -0.01 207520.0 -139000.0 -0.81 -0.5748 -0.7124 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G18 compound treatment 311060.0 -127000.0 -0.71 295790.0 -50900.0 -0.29 -0.7136 -0.9234 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G19 mock treatment 484670.0 46700.0 0.26 330780.0 -15900.0 -0.09 0.1209 0.434 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G20 mock treatment 393720.0 -44200.0 -0.25 370510.0 23900.0 0.14 -0.0782 -0.2744 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G21 compound treatment 502270.0 64300.0 0.36 539840.0 193000.0 1.12 1.0483 0.8903 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G22 compound treatment 415960.0 -22000.0 -0.12 337250.0 -9390.0 -0.05 -0.126 -0.932 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G23 compound treatment 25280.0 -413000.0 -2.32 28990.0 -318000.0 -1.84 -2.9453 -0.9934 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 G24 compound treatment 347450.0 -90500.0 -0.51 441090.0 94400.0 0.55 0.0271 0.0362 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H01 compound treatment 553930.0 116000.0 0.65 130840.0 -216000.0 -1.25 -0.4233 -0.2999 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H02 compound treatment 207210.0 -231000.0 -1.3 241650.0 -105000.0 -0.61 -1.349 -0.9404 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H03 mock treatment 341230.0 -96700.0 -0.54 204000.0 -143000.0 -0.83 -0.97 -0.9794 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H04 mock treatment 539400.0 101000.0 0.57 147960.0 -199000.0 -1.15 -0.4109 -0.3195 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H05 compound treatment 240840.0 -197000.0 -1.11 289680.0 -57000.0 -0.33 -1.0182 -0.8795 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H06 compound treatment 496960.0 59000.0 0.33 589520.0 243000.0 1.41 1.2309 0.8505 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H07 compound treatment 282800.0 -155000.0 -0.87 394920.0 48300.0 0.28 -0.4196 -0.4575 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H08 compound treatment 417940.0 -20000.0 -0.11 259330.0 -87300.0 -0.51 -0.4377 -0.8438 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H09 compound treatment 601360.0 163000.0 0.92 399550.0 52900.0 0.31 0.8675 0.8945 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H10 compound treatment 409120.0 -28800.0 -0.16 229400.0 -117000.0 -0.68 -0.5955 -0.852 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H11 compound treatment 447330.0 9380.0 0.05 176010.0 -171000.0 -0.99 -0.6624 -0.6684 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H12 compound treatment 457340.0 19400.0 0.11 226480.0 -120000.0 -0.7 -0.4156 -0.5892 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H13 compound treatment 496820.0 58900.0 0.33 148510.0 -198000.0 -1.15 -0.5782 -0.4835 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H14 compound treatment 350270.0 -87700.0 -0.49 300280.0 -46400.0 -0.27 -0.5391 -0.9592 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H15 compound treatment 282040.0 -156000.0 -0.88 294650.0 -52000.0 -0.3 -0.8338 -0.8985 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H16 compound treatment 542830.0 105000.0 0.59 290210.0 -56400.0 -0.33 0.1861 0.2756 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H17 compound treatment 389660.0 -48300.0 -0.27 414460.0 67800.0 0.39 0.0859 0.1796 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H18 compound treatment 422720.0 -15200.0 -0.09 494370.0 148000.0 0.86 0.5452 0.6332 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H19 mock treatment 624760.0 187000.0 1.05 348750.0 2110.0 0.01 0.7523 0.7153 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H20 mock treatment 484500.0 46600.0 0.26 527040.0 180000.0 1.05 0.9251 0.8577 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H21 compound treatment 496550.0 58600.0 0.33 486040.0 139000.0 0.81 0.8049 0.9219 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H22 compound treatment 365890.0 -72100.0 -0.41 300480.0 -46200.0 -0.27 -0.4761 -0.9797 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H23 compound treatment 313640.0 -124000.0 -0.7 335010.0 -11600.0 -0.07 -0.5425 -0.7717 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 H24 compound treatment 338480.0 -99500.0 -0.56 262110.0 -84500.0 -0.49 -0.7426 -0.9978 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I01 compound treatment 551790.0 114000.0 0.64 525760.0 179000.0 1.04 1.1877 0.9731 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I02 compound treatment 493040.0 55100.0 0.31 489350.0 143000.0 0.83 0.8045 0.9103 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I03 compound treatment 178600.0 -259000.0 -1.46 270520.0 -76100.0 -0.44 -1.3445 -0.8815 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I04 compound treatment 280910.0 -157000.0 -0.88 452360.0 106000.0 0.61 -0.1916 -0.1781 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I05 mock treatment 552760.0 115000.0 0.65 400220.0 53600.0 0.31 0.6767 0.9437 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I06 mock treatment 350090.0 -87900.0 -0.49 275240.0 -71400.0 -0.41 -0.6425 -0.9961 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I07 compound treatment 189230.0 -249000.0 -1.4 151610.0 -195000.0 -1.13 -1.7899 -0.9944 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I08 compound treatment 337690.0 -100000.0 -0.56 385200.0 38600.0 0.22 -0.241 -0.3969 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I09 compound treatment 401980.0 -36000.0 -0.2 418500.0 71900.0 0.42 0.1515 0.327 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I10 compound treatment 651850.0 214000.0 1.2 239970.0 -107000.0 -0.62 0.414 0.3058 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I11 compound treatment 320900.0 -117000.0 -0.66 308860.0 -37800.0 -0.22 -0.6209 -0.8941 BCB03_000168 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I12 compound treatment 261480.0 -176000.0 -0.99 285000.0 -61600.0 -0.36 -0.9552 -0.9048 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I13 compound treatment 9920.0 -428000.0 -2.41 8000.0 -339000.0 -1.96 -3.0926 -0.9948 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I14 compound treatment 333980.0 -104000.0 -0.59 498030.0 151000.0 0.88 0.2069 0.1961 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I15 compound treatment 280020.0 -158000.0 -0.89 414410.0 67800.0 0.39 -0.3508 -0.3608 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I16 compound treatment 270080.0 -168000.0 -0.95 223800.0 -123000.0 -0.71 -1.172 -0.9903 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I17 compound treatment 584170.0 146000.0 0.82 339450.0 -7190.0 -0.04 0.5526 0.6704 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I18 compound treatment 449010.0 11100.0 0.06 314010.0 -32600.0 -0.19 -0.0898 -0.4507 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I19 compound treatment 183720.0 -254000.0 -1.43 150740.0 -196000.0 -1.14 -1.8154 -0.9935 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I20 compound treatment 392960.0 -45000.0 -0.25 228570.0 -118000.0 -0.68 -0.6633 -0.9085 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I21 mock treatment 370740.0 -67200.0 -0.38 429650.0 83000.0 0.48 0.0729 0.119 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I22 mock treatment 312710.0 -125000.0 -0.71 286980.0 -59700.0 -0.35 -0.7432 -0.9463 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I23 compound treatment 324480.0 -113000.0 -0.64 275260.0 -71400.0 -0.41 -0.7444 -0.978 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 I24 compound treatment 442080.0 4130.0 0.02 365070.0 18400.0 0.11 0.092 0.8413 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J01 compound treatment 187750.0 -250000.0 -1.41 230090.0 -117000.0 -0.68 -1.4739 -0.9434 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J02 compound treatment 168820.0 -269000.0 -1.52 273450.0 -73200.0 -0.42 -1.3715 -0.8717 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J03 compound treatment 471700.0 33800.0 0.19 557940.0 211000.0 1.23 1.0008 0.8071 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J04 compound treatment 542790.0 105000.0 0.59 163840.0 -183000.0 -1.06 -0.3323 -0.2739 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J05 mock treatment 450110.0 12200.0 0.07 274100.0 -72500.0 -0.42 -0.2491 -0.5844 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J06 mock treatment 552830.0 115000.0 0.65 295760.0 -50900.0 -0.3 0.2486 0.3498 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J07 compound treatment 545560.0 108000.0 0.61 198200.0 -148000.0 -0.86 -0.1804 -0.1713 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J08 compound treatment 85120.0 -353000.0 -1.99 99240.0 -247000.0 -1.43 -2.419 -0.9873 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J09 compound treatment 308480.0 -129000.0 -0.73 310300.0 -36300.0 -0.21 -0.6644 -0.8757 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J10 compound treatment 477460.0 39500.0 0.22 300280.0 -46400.0 -0.27 -0.0328 -0.0941 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J11 compound treatment 201880.0 -236000.0 -1.33 567060.0 220000.0 1.28 -0.0358 -0.0194 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J12 compound treatment 584380.0 146000.0 0.82 206900.0 -140000.0 -0.81 0.0098 0.0085 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J13 compound treatment 402370.0 -35600.0 -0.2 376720.0 30100.0 0.17 -0.0183 -0.0688 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J14 compound treatment 488610.0 50700.0 0.29 364550.0 17900.0 0.1 0.2751 0.9064 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J15 compound treatment 303230.0 -135000.0 -0.76 261390.0 -85300.0 -0.49 -0.8859 -0.9785 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J16 compound treatment 428160.0 -9790.0 -0.06 294320.0 -52300.0 -0.3 -0.2535 -0.8221 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J17 compound treatment 258400.0 -180000.0 -1.01 352340.0 5700.0 0.03 -0.6914 -0.6836 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J18 compound treatment 433830.0 -4120.0 -0.02 340340.0 -6300.0 -0.04 -0.0422 -0.9759 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J19 compound treatment 577680.0 140000.0 0.79 327330.0 -19300.0 -0.11 0.477 0.6004 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J20 compound treatment 331890.0 -106000.0 -0.6 262500.0 -84100.0 -0.49 -0.7672 -0.995 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J21 mock treatment 373760.0 -64200.0 -0.36 463070.0 116000.0 0.68 0.2219 0.2898 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J22 mock treatment 398930.0 -39000.0 -0.22 349070.0 2430.0 0.01 -0.1454 -0.6604 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J23 compound treatment 339250.0 -98700.0 -0.56 462800.0 116000.0 0.67 0.0835 0.0956 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 J24 compound treatment 312820.0 -125000.0 -0.7 327000.0 -19600.0 -0.11 -0.5786 -0.8109 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K01 compound treatment 257000.0 -181000.0 -1.02 503110.0 156000.0 0.91 -0.0787 -0.0577 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K02 compound treatment 341520.0 -96400.0 -0.54 399580.0 52900.0 0.31 -0.1668 -0.2674 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K03 compound treatment 162940.0 -275000.0 -1.55 557470.0 211000.0 1.22 -0.2302 -0.1167 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K04 compound treatment 390420.0 -47500.0 -0.27 488130.0 141000.0 0.82 0.391 0.4531 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K05 compound treatment 10640.0 -427000.0 -2.41 9830.0 -337000.0 -1.95 -3.0822 -0.9947 1107217 BCB03_000204 Cc1cccnc1I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K06 compound treatment 357050.0 -80900.0 -0.46 270370.0 -76300.0 -0.44 -0.6348 -0.9999 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K07 mock treatment 570260.0 132000.0 0.74 254010.0 -92600.0 -0.54 0.1468 0.1599 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K08 mock treatment 618080.0 180000.0 1.01 335410.0 -11200.0 -0.07 0.671 0.6603 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K09 compound treatment 586080.0 148000.0 0.83 627750.0 281000.0 1.63 1.7424 0.9515 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K10 compound treatment 319210.0 -119000.0 -0.67 159250.0 -187000.0 -1.09 -1.2411 -0.9728 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K11 compound treatment 514270.0 76300.0 0.43 506050.0 159000.0 0.92 0.9575 0.9393 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K12 compound treatment 476700.0 38800.0 0.22 215900.0 -131000.0 -0.76 -0.3819 -0.484 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K13 compound treatment 199690.0 -238000.0 -1.34 349320.0 2680.0 0.02 -0.9375 -0.6989 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K14 compound treatment 461950.0 24000.0 0.14 463460.0 117000.0 0.68 0.5746 0.8317 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K15 mock treatment 494420.0 56500.0 0.32 336930.0 -9710.0 -0.06 0.185 0.5729 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K16 mock treatment 429600.0 -8350.0 -0.05 480240.0 134000.0 0.77 0.5146 0.663 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K17 compound treatment 446670.0 8720.0 0.05 332820.0 -13800.0 -0.08 -0.022 -0.2337 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K18 compound treatment 394760.0 -43200.0 -0.24 495170.0 149000.0 0.86 0.4372 0.4884 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K19 compound treatment 430050.0 -7900.0 -0.04 440760.0 94100.0 0.55 0.3545 0.6474 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K20 compound treatment 374590.0 -63400.0 -0.36 385040.0 38400.0 0.22 -0.0947 -0.2253 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K21 compound treatment 429650.0 -8300.0 -0.05 308110.0 -38500.0 -0.22 -0.191 -0.8369 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K22 compound treatment 424450.0 -13500.0 -0.08 329970.0 -16700.0 -0.1 -0.1221 -0.9929 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K23 mock treatment 337570.0 -100000.0 -0.57 285720.0 -60900.0 -0.35 -0.6494 -0.9744 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 K24 mock treatment 389570.0 -48400.0 -0.27 188610.0 -158000.0 -0.92 -0.8406 -0.8792 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L01 compound treatment 157880.0 -280000.0 -1.58 284510.0 -62100.0 -0.36 -1.3697 -0.8469 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L02 compound treatment 371290.0 -66700.0 -0.38 205120.0 -142000.0 -0.82 -0.8457 -0.9371 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L03 compound treatment 454990.0 17000.0 0.1 293860.0 -52800.0 -0.31 -0.1486 -0.4633 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L04 compound treatment 217720.0 -220000.0 -1.24 221760.0 -125000.0 -0.72 -1.3888 -0.9672 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L05 compound treatment 257010.0 -181000.0 -1.02 348640.0 2000.0 0.01 -0.7121 -0.699 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L06 compound treatment 254780.0 -183000.0 -1.03 176350.0 -170000.0 -0.99 -1.4275 -0.9998 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L07 mock treatment 443270.0 5320.0 0.03 258440.0 -88200.0 -0.51 -0.3405 -0.6646 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L08 mock treatment 277350.0 -161000.0 -0.9 269490.0 -77200.0 -0.45 -0.9557 -0.9474 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L09 compound treatment 599490.0 162000.0 0.91 360410.0 13800.0 0.08 0.6995 0.7662 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L10 compound treatment 327560.0 -110000.0 -0.62 272000.0 -74600.0 -0.43 -0.7455 -0.9844 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L11 compound treatment 284980.0 -153000.0 -0.86 235390.0 -111000.0 -0.65 -1.0651 -0.9899 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L12 compound treatment 257760.0 -180000.0 -1.01 229780.0 -117000.0 -0.68 -1.1965 -0.9808 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L13 compound treatment 585220.0 147000.0 0.83 300010.0 -46600.0 -0.27 0.395 0.453 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L14 compound treatment 240660.0 -197000.0 -1.11 316870.0 -29800.0 -0.17 -0.9074 -0.8073 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L15 mock treatment 377450.0 -60500.0 -0.34 243320.0 -103000.0 -0.6 -0.6645 -0.9642 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L16 mock treatment 549810.0 112000.0 0.63 259640.0 -87000.0 -0.5 0.0885 0.1097 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L17 compound treatment 431840.0 -6110.0 -0.03 430300.0 83700.0 0.49 0.3187 0.6553 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L18 compound treatment 396580.0 -41400.0 -0.23 413780.0 67100.0 0.39 0.1106 0.2439 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L19 compound treatment 423040.0 -14900.0 -0.08 291450.0 -55200.0 -0.32 -0.2857 -0.8633 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L20 compound treatment 271040.0 -167000.0 -0.94 319390.0 -27300.0 -0.16 -0.7762 -0.8146 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L21 compound treatment 455910.0 18000.0 0.1 368480.0 21800.0 0.13 0.161 0.9938 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L22 compound treatment 450730.0 12800.0 0.07 171690.0 -175000.0 -1.01 -0.6666 -0.6553 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L23 mock treatment 484710.0 46800.0 0.26 389090.0 42400.0 0.25 0.3602 0.9994 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 L24 mock treatment 529280.0 91300.0 0.51 284520.0 -62100.0 -0.36 0.1088 0.1733 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M01 compound treatment 272070.0 -166000.0 -0.93 463170.0 117000.0 0.68 -0.1825 -0.1583 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M02 compound treatment 375970.0 -62000.0 -0.35 307680.0 -39000.0 -0.23 -0.4065 -0.9779 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M03 compound treatment 206950.0 -231000.0 -1.3 254880.0 -91800.0 -0.53 -1.2958 -0.9222 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M04 compound treatment 439250.0 1300.0 0.01 477730.0 131000.0 0.76 0.5427 0.7139 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M05 compound treatment 309070.0 -129000.0 -0.73 400360.0 53700.0 0.31 -0.2927 -0.3708 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M06 compound treatment 438310.0 361.0 0.0 201920.0 -145000.0 -0.84 -0.592 -0.7054 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M07 compound treatment 340410.0 -97500.0 -0.55 579890.0 233000.0 1.35 0.5682 0.3892 3000956 BCB03_000242 CCCc1cccc(=O)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M08 compound treatment 395700.0 -42200.0 -0.24 498240.0 152000.0 0.88 0.4535 0.4979 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M09 mock treatment 513060.0 75100.0 0.42 467680.0 121000.0 0.7 0.7953 0.9706 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M10 mock treatment 585710.0 148000.0 0.83 448080.0 101000.0 0.59 1.0042 0.9856 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M11 compound treatment 397770.0 -40200.0 -0.23 405240.0 58600.0 0.34 0.0804 0.1968 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M12 compound treatment 419050.0 -18900.0 -0.11 379520.0 32900.0 0.19 0.0596 0.2729 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M13 mock treatment 475740.0 37800.0 0.21 316580.0 -30100.0 -0.17 0.0272 0.0987 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M14 mock treatment 487080.0 49100.0 0.28 543920.0 197000.0 1.14 1.0046 0.8535 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M15 compound treatment 509780.0 71800.0 0.4 495330.0 149000.0 0.86 0.8957 0.9404 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M16 compound treatment 316520.0 -121000.0 -0.68 195270.0 -151000.0 -0.88 -1.1041 -0.9923 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M17 compound treatment 246660.0 -191000.0 -1.08 422640.0 76000.0 0.44 -0.4498 -0.3866 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M18 compound treatment 395710.0 -42200.0 -0.24 257090.0 -89600.0 -0.52 -0.5354 -0.9373 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M19 compound treatment 535590.0 97600.0 0.55 348880.0 2240.0 0.01 0.3979 0.7236 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M20 compound treatment 557060.0 119000.0 0.67 273050.0 -73600.0 -0.43 0.1724 0.2168 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M21 compound treatment 286090.0 -152000.0 -0.85 345790.0 -852.0 0.0 -0.608 -0.7112 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M22 compound treatment 334180.0 -104000.0 -0.58 199210.0 -147000.0 -0.86 -1.0177 -0.9827 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M23 compound treatment 441240.0 3290.0 0.02 336690.0 -9950.0 -0.06 -0.0277 -0.4572 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 M24 compound treatment 430360.0 -7590.0 -0.04 354780.0 8140.0 0.05 0.0032 0.0497 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N01 compound treatment 544210.0 106000.0 0.6 177390.0 -169000.0 -0.98 -0.2711 -0.2358 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N02 compound treatment 534400.0 96500.0 0.54 291780.0 -54900.0 -0.32 0.159 0.2526 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N03 compound treatment 545140.0 107000.0 0.6 520930.0 174000.0 1.01 1.1414 0.9696 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N04 compound treatment 491810.0 53900.0 0.3 241180.0 -105000.0 -0.61 -0.2181 -0.3195 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N05 compound treatment 248810.0 -189000.0 -1.06 446480.0 99800.0 0.58 -0.3435 -0.2834 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N06 compound treatment 281870.0 -156000.0 -0.88 243410.0 -103000.0 -0.6 -1.0446 -0.9825 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N07 compound treatment 274420.0 -164000.0 -0.92 347430.0 788.0 0.0 -0.6477 -0.7036 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N08 compound treatment 288480.0 -149000.0 -0.84 173440.0 -173000.0 -1.0 -1.3053 -0.9961 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N09 mock treatment 516730.0 78800.0 0.44 282890.0 -63800.0 -0.37 0.0522 0.0903 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N10 mock treatment 386120.0 -51800.0 -0.29 483300.0 137000.0 0.79 0.3541 0.4193 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N11 compound treatment 525280.0 87300.0 0.49 572810.0 226000.0 1.31 1.2751 0.9103 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N12 compound treatment 564700.0 127000.0 0.71 567620.0 221000.0 1.28 1.4107 0.9618 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N13 mock treatment 539130.0 101000.0 0.57 407260.0 60600.0 0.35 0.6514 0.9731 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N14 mock treatment 231890.0 -206000.0 -1.16 401810.0 55200.0 0.32 -0.594 -0.4936 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N15 compound treatment 562520.0 125000.0 0.7 425820.0 79200.0 0.46 0.8206 0.9789 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N16 compound treatment 506150.0 68200.0 0.38 435270.0 88600.0 0.51 0.6349 0.9897 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N17 compound treatment 557980.0 120000.0 0.68 430960.0 84300.0 0.49 0.8236 0.9874 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N18 compound treatment 432380.0 -5570.0 -0.03 371440.0 24800.0 0.14 0.0795 0.5403 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N19 compound treatment 393350.0 -44600.0 -0.25 350290.0 3650.0 0.02 -0.1626 -0.6452 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N20 compound treatment 330160.0 -108000.0 -0.61 240830.0 -106000.0 -0.61 -0.863 -1.0 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N21 compound treatment 309550.0 -128000.0 -0.72 453510.0 107000.0 0.62 -0.0729 -0.0765 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N22 compound treatment 343490.0 -94500.0 -0.53 261700.0 -84900.0 -0.49 -0.7243 -0.9993 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N23 compound treatment 450790.0 12800.0 0.07 353380.0 6740.0 0.04 0.0787 0.9583 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 N24 compound treatment 322990.0 -115000.0 -0.65 417650.0 71000.0 0.41 -0.1664 -0.217 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O01 compound treatment 365090.0 -72900.0 -0.41 216560.0 -130000.0 -0.75 -0.8235 -0.959 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O02 compound treatment 345470.0 -92500.0 -0.52 238940.0 -108000.0 -0.62 -0.8098 -0.9959 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O03 compound treatment 474930.0 37000.0 0.21 440570.0 93900.0 0.54 0.5324 0.9129 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O04 compound treatment 385980.0 -52000.0 -0.29 257550.0 -89100.0 -0.52 -0.5722 -0.9637 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O05 compound treatment 345810.0 -92100.0 -0.52 390880.0 44200.0 0.26 -0.1854 -0.3203 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O06 compound treatment 273720.0 -164000.0 -0.92 447170.0 101000.0 0.58 -0.2415 -0.2209 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O07 compound treatment 544430.0 106000.0 0.6 368430.0 21800.0 0.13 0.5132 0.8378 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O08 compound treatment 221710.0 -216000.0 -1.22 412820.0 66200.0 0.38 -0.5894 -0.4618 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O09 compound treatment 466310.0 28400.0 0.16 519900.0 173000.0 1.0 0.8234 0.8093 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O10 compound treatment 584650.0 147000.0 0.83 454530.0 108000.0 0.63 1.0264 0.9906 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O11 mock treatment 421730.0 -16200.0 -0.09 277240.0 -69400.0 -0.4 -0.3492 -0.846 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O12 mock treatment 464540.0 26600.0 0.15 245870.0 -101000.0 -0.58 -0.3074 -0.5095 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O13 compound treatment 270450.0 -167000.0 -0.94 298100.0 -48500.0 -0.28 -0.8658 -0.8798 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O14 compound treatment 516560.0 78600.0 0.44 521850.0 175000.0 1.02 1.0314 0.9306 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O15 compound treatment 282520.0 -155000.0 -0.87 447410.0 101000.0 0.58 -0.2055 -0.1953 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O16 compound treatment 398980.0 -39000.0 -0.22 504800.0 158000.0 0.92 0.4935 0.5232 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O17 compound treatment 303760.0 -134000.0 -0.76 512020.0 165000.0 0.96 0.144 0.118 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O18 compound treatment 465010.0 27100.0 0.15 447300.0 101000.0 0.58 0.5205 0.8627 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O19 compound treatment 345400.0 -92500.0 -0.52 385650.0 39000.0 0.23 -0.2084 -0.367 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O20 compound treatment 472700.0 34800.0 0.2 452430.0 106000.0 0.61 0.5721 0.8885 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O21 compound treatment 345060.0 -92900.0 -0.52 340870.0 -5770.0 -0.03 -0.3934 -0.7508 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O22 compound treatment 470660.0 32700.0 0.18 527330.0 181000.0 1.05 0.8712 0.8188 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O23 compound treatment 493050.0 55100.0 0.31 408810.0 62200.0 0.36 0.4743 0.9972 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 O24 compound treatment 333720.0 -104000.0 -0.59 399100.0 52500.0 0.3 -0.1998 -0.3023 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P01 compound treatment 358620.0 -79300.0 -0.45 345640.0 -1000.0 -0.01 -0.3199 -0.7162 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P02 compound treatment 161710.0 -276000.0 -1.56 293130.0 -53500.0 -0.31 -1.3191 -0.8318 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P03 compound treatment 371140.0 -66800.0 -0.38 313840.0 -32800.0 -0.19 -0.4005 -0.9501 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P04 compound treatment 210340.0 -228000.0 -1.28 199310.0 -147000.0 -0.85 -1.5102 -0.9806 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P05 compound treatment 248160.0 -190000.0 -1.07 329250.0 -17400.0 -0.1 -0.8268 -0.7704 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P06 compound treatment 275870.0 -162000.0 -0.91 148320.0 -198000.0 -1.15 -1.4585 -0.9934 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P07 compound treatment 301090.0 -137000.0 -0.77 229610.0 -117000.0 -0.68 -1.0247 -0.998 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P08 compound treatment 273520.0 -164000.0 -0.93 220830.0 -126000.0 -0.73 -1.1705 -0.9931 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P09 compound treatment 359040.0 -78900.0 -0.44 248770.0 -97900.0 -0.57 -0.7155 -0.9926 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P10 compound treatment 248110.0 -190000.0 -1.07 295950.0 -50700.0 -0.29 -0.9636 -0.8693 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P11 mock treatment 460200.0 22300.0 0.13 252520.0 -94100.0 -0.55 -0.2974 -0.531 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P12 mock treatment 280640.0 -157000.0 -0.89 190810.0 -156000.0 -0.9 -1.2652 -0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P13 compound treatment 390240.0 -47700.0 -0.27 225160.0 -121000.0 -0.7 -0.6881 -0.9126 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P14 compound treatment 336960.0 -101000.0 -0.57 236640.0 -110000.0 -0.64 -0.8531 -0.9983 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P15 compound treatment 266190.0 -172000.0 -0.97 207440.0 -139000.0 -0.81 -1.2546 -0.996 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P16 compound treatment 391470.0 -46500.0 -0.26 358610.0 12000.0 0.07 -0.1359 -0.5022 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P17 compound treatment 375200.0 -62700.0 -0.35 483960.0 137000.0 0.8 0.3133 0.3597 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P18 compound treatment 278100.0 -160000.0 -0.9 278020.0 -68600.0 -0.4 -0.9177 -0.9327 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P19 compound treatment 198280.0 -240000.0 -1.35 289930.0 -56700.0 -0.33 -1.1866 -0.8545 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P20 compound treatment 317620.0 -120000.0 -0.68 252420.0 -94200.0 -0.55 -0.8654 -0.9943 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P21 compound treatment 119280.0 -319000.0 -1.79 113040.0 -234000.0 -1.35 -2.2265 -0.9904 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P22 compound treatment 284050.0 -154000.0 -0.87 292540.0 -54100.0 -0.31 -0.8345 -0.9056 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P23 compound treatment 300800.0 -137000.0 -0.77 294200.0 -52400.0 -0.3 -0.761 -0.9171 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2281 P24 compound treatment 147290.0 -291000.0 -1.64 173920.0 -173000.0 -1.0 -1.8653 -0.9723 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A01 compound treatment 444920.0 7450.0 0.04 423320.0 67200.0 0.39 0.3053 0.7787 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A02 compound treatment 263250.0 -174000.0 -0.98 211400.0 -145000.0 -0.84 -1.2869 -0.997 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A03 compound treatment 521550.0 84100.0 0.47 214930.0 -141000.0 -0.82 -0.2442 -0.2583 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A04 compound treatment 316830.0 -121000.0 -0.68 245870.0 -110000.0 -0.64 -0.9323 -0.9995 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A05 compound treatment 182030.0 -255000.0 -1.44 184430.0 -172000.0 -1.0 -1.7208 -0.9839 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A06 compound treatment 372440.0 -65000.0 -0.37 208680.0 -147000.0 -0.85 -0.8634 -0.9284 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A07 compound treatment 490260.0 52800.0 0.3 153070.0 -203000.0 -1.18 -0.6225 -0.5126 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A08 compound treatment 243520.0 -194000.0 -1.09 208330.0 -148000.0 -0.86 -1.378 -0.9928 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A09 compound treatment 327850.0 -110000.0 -0.62 284890.0 -71200.0 -0.41 -0.7284 -0.9809 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A10 compound treatment 440080.0 2610.0 0.01 246000.0 -110000.0 -0.64 -0.4411 -0.6907 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A11 compound treatment 280030.0 -157000.0 -0.89 165280.0 -191000.0 -1.11 -1.4093 -0.9939 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A12 compound treatment 221010.0 -216000.0 -1.22 296170.0 -59900.0 -0.35 -1.1074 -0.8739 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A13 mock treatment 329650.0 -108000.0 -0.61 213850.0 -142000.0 -0.82 -1.0126 -0.9886 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A14 mock treatment 494130.0 56700.0 0.32 170140.0 -186000.0 -1.08 -0.5371 -0.4775 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A15 compound treatment 545200.0 108000.0 0.61 340330.0 -15800.0 -0.09 0.3641 0.5937 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A16 compound treatment 176700.0 -261000.0 -1.47 216640.0 -139000.0 -0.81 -1.61 -0.9606 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A17 compound treatment 474980.0 37500.0 0.21 184110.0 -172000.0 -1.0 -0.556 -0.5453 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A18 compound treatment 565760.0 128000.0 0.72 220160.0 -136000.0 -0.79 -0.0468 -0.0438 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A19 compound treatment 471100.0 33600.0 0.19 195450.0 -161000.0 -0.93 -0.5249 -0.5521 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A20 compound treatment 322370.0 -115000.0 -0.65 335540.0 -20600.0 -0.12 -0.5425 -0.8234 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A21 compound treatment 314190.0 -123000.0 -0.69 251010.0 -105000.0 -0.61 -0.9217 -0.9979 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A22 compound treatment 285600.0 -152000.0 -0.85 172160.0 -184000.0 -1.07 -1.3589 -0.994 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A23 compound treatment 266610.0 -171000.0 -0.96 179610.0 -176000.0 -1.02 -1.4039 -0.9995 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 A24 compound treatment 537060.0 99600.0 0.56 473450.0 117000.0 0.68 0.8776 0.9954 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B01 compound treatment 300800.0 -137000.0 -0.77 181370.0 -175000.0 -1.01 -1.2606 -0.9908 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B02 compound treatment 370670.0 -66800.0 -0.38 218030.0 -138000.0 -0.8 -0.8321 -0.9406 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B03 compound treatment 541240.0 104000.0 0.58 256410.0 -99700.0 -0.58 0.0042 0.0052 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B04 compound treatment 459680.0 22200.0 0.13 388890.0 32800.0 0.19 0.2229 0.9793 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B05 compound treatment 521440.0 84000.0 0.47 512090.0 156000.0 0.9 0.9739 0.9542 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B06 compound treatment 196480.0 -241000.0 -1.36 209050.0 -147000.0 -0.85 -1.5623 -0.975 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B07 compound treatment 509720.0 72200.0 0.41 336670.0 -19400.0 -0.11 0.2079 0.4926 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B08 compound treatment 318080.0 -119000.0 -0.67 384580.0 28500.0 0.17 -0.3585 -0.518 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B09 compound treatment 377520.0 -60000.0 -0.34 488100.0 132000.0 0.77 0.3026 0.3618 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B10 compound treatment 389180.0 -48300.0 -0.27 299520.0 -56600.0 -0.33 -0.4243 -0.9956 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B11 compound treatment 560270.0 123000.0 0.69 296000.0 -60100.0 -0.35 0.2423 0.313 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B12 compound treatment 61700.0 -376000.0 -2.12 17060.0 -339000.0 -1.97 -2.8862 -0.9993 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B13 mock treatment 543840.0 106000.0 0.6 481120.0 125000.0 0.73 0.9361 0.9955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B14 mock treatment 543170.0 106000.0 0.6 315890.0 -40200.0 -0.23 0.2558 0.4003 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B15 compound treatment 602110.0 165000.0 0.93 412750.0 56600.0 0.33 0.8877 0.9027 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B16 compound treatment 32340.0 -405000.0 -2.28 25230.0 -331000.0 -1.92 -2.9695 -0.9963 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B17 compound treatment 583520.0 146000.0 0.82 483090.0 127000.0 0.74 1.1021 0.9985 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B18 compound treatment 487050.0 49600.0 0.28 400430.0 44300.0 0.26 0.3791 0.9992 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B19 compound treatment 368550.0 -68900.0 -0.39 362400.0 6300.0 0.04 -0.2485 -0.6377 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B20 compound treatment 369230.0 -68200.0 -0.38 319040.0 -37100.0 -0.21 -0.4236 -0.9624 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B21 compound treatment 308690.0 -129000.0 -0.72 368920.0 12800.0 0.07 -0.4601 -0.6313 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B22 compound treatment 377120.0 -60400.0 -0.34 295620.0 -60500.0 -0.35 -0.4883 -0.9999 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B23 compound treatment 508080.0 70600.0 0.4 377030.0 20900.0 0.12 0.3669 0.8828 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 B24 compound treatment 323580.0 -114000.0 -0.64 428500.0 72400.0 0.42 -0.1565 -0.2042 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C01 compound treatment 192640.0 -245000.0 -1.38 352170.0 -3930.0 -0.02 -0.9907 -0.7187 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C02 compound treatment 384420.0 -53100.0 -0.3 303620.0 -52500.0 -0.3 -0.4264 -1.0 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C03 compound treatment 546910.0 109000.0 0.62 377380.0 21300.0 0.12 0.5229 0.8322 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C04 compound treatment 488000.0 50500.0 0.28 238780.0 -117000.0 -0.68 -0.28 -0.3796 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C05 compound treatment 180800.0 -257000.0 -1.44 244010.0 -112000.0 -0.65 -1.4814 -0.935 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C06 compound treatment 325030.0 -112000.0 -0.63 315080.0 -41000.0 -0.24 -0.6158 -0.9107 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C07 compound treatment 314360.0 -123000.0 -0.69 186720.0 -169000.0 -0.98 -1.1847 -0.9854 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C08 compound treatment 495280.0 57800.0 0.33 291040.0 -65100.0 -0.38 -0.0367 -0.0736 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C09 compound treatment 287270.0 -150000.0 -0.85 305760.0 -50300.0 -0.29 -0.8044 -0.8992 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C10 compound treatment 393280.0 -44200.0 -0.25 263600.0 -92500.0 -0.54 -0.5553 -0.939 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C11 mock treatment 420530.0 -16900.0 -0.1 242880.0 -113000.0 -0.66 -0.5317 -0.8014 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C12 mock treatment 377860.0 -59600.0 -0.34 326350.0 -29800.0 -0.17 -0.3593 -0.9522 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C13 compound treatment 387850.0 -49600.0 -0.28 217150.0 -139000.0 -0.81 -0.7673 -0.8997 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C14 compound treatment 512330.0 74900.0 0.42 253400.0 -103000.0 -0.6 -0.1232 -0.1688 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C15 mock treatment 271680.0 -166000.0 -0.93 502840.0 147000.0 0.85 -0.0582 -0.0461 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C16 mock treatment 431070.0 -6400.0 -0.04 370900.0 14800.0 0.09 0.0352 0.3782 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C17 compound treatment 361460.0 -76000.0 -0.43 374130.0 18000.0 0.1 -0.2287 -0.5191 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C18 compound treatment 343810.0 -93700.0 -0.53 255230.0 -101000.0 -0.59 -0.7865 -0.9987 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C19 compound treatment 522880.0 85400.0 0.48 284100.0 -72000.0 -0.42 0.0447 0.0702 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C20 compound treatment 374520.0 -63000.0 -0.35 272960.0 -83100.0 -0.48 -0.5915 -0.9885 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C21 compound treatment 475740.0 38300.0 0.22 183000.0 -173000.0 -1.0 -0.5575 -0.543 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C22 compound treatment 333960.0 -104000.0 -0.58 248230.0 -108000.0 -0.63 -0.8544 -0.9994 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C23 compound treatment 350080.0 -87400.0 -0.49 309870.0 -46200.0 -0.27 -0.5375 -0.9593 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 C24 compound treatment 365660.0 -71800.0 -0.4 342050.0 -14100.0 -0.08 -0.3435 -0.8329 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D01 compound treatment 453400.0 15900.0 0.09 452110.0 96000.0 0.56 0.4571 0.8105 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D02 compound treatment 532110.0 94600.0 0.53 454660.0 98600.0 0.57 0.7809 0.9994 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D03 compound treatment 469030.0 31600.0 0.18 374340.0 18200.0 0.11 0.2004 0.9693 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D04 compound treatment 449760.0 12300.0 0.07 410020.0 53900.0 0.31 0.27 0.8432 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D05 compound treatment 354400.0 -83100.0 -0.47 510260.0 154000.0 0.89 0.3015 0.2988 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D06 compound treatment 403920.0 -33600.0 -0.19 257440.0 -98700.0 -0.57 -0.5382 -0.8931 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D07 compound treatment 411080.0 -26400.0 -0.15 196980.0 -159000.0 -0.92 -0.7576 -0.8105 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D08 compound treatment 327540.0 -110000.0 -0.62 262780.0 -93300.0 -0.54 -0.8203 -0.9978 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D09 compound treatment 504720.0 67200.0 0.38 402240.0 46100.0 0.27 0.4569 0.9856 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D10 compound treatment 226240.0 -211000.0 -1.19 171250.0 -185000.0 -1.07 -1.5989 -0.9987 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D11 mock treatment 536510.0 99000.0 0.56 490740.0 135000.0 0.78 0.9464 0.9864 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D12 mock treatment 569680.0 132000.0 0.74 374240.0 18100.0 0.11 0.6007 0.7991 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D13 compound treatment 472770.0 35300.0 0.2 327900.0 -28200.0 -0.16 0.0249 0.0966 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D14 compound treatment 378340.0 -59100.0 -0.33 187200.0 -169000.0 -0.98 -0.928 -0.897 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D15 mock treatment 534080.0 96600.0 0.54 474340.0 118000.0 0.69 0.8694 0.9934 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D16 mock treatment 558300.0 121000.0 0.68 534250.0 178000.0 1.03 1.2115 0.9794 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D17 compound treatment 350080.0 -87400.0 -0.49 193570.0 -163000.0 -0.94 -1.0144 -0.954 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D18 compound treatment 456390.0 18900.0 0.11 224890.0 -131000.0 -0.76 -0.4628 -0.6023 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D19 compound treatment 285030.0 -152000.0 -0.86 407490.0 51400.0 0.3 -0.3961 -0.436 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D20 compound treatment 208190.0 -229000.0 -1.29 173090.0 -183000.0 -1.06 -1.6632 -0.9953 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D21 compound treatment 365490.0 -72000.0 -0.41 154280.0 -202000.0 -1.17 -1.1142 -0.8995 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D22 compound treatment 367120.0 -70400.0 -0.4 320960.0 -35100.0 -0.2 -0.4242 -0.9523 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D23 compound treatment 443780.0 6310.0 0.04 194580.0 -162000.0 -0.94 -0.6373 -0.6798 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 D24 compound treatment 283840.0 -154000.0 -0.86 357760.0 1660.0 0.01 -0.6048 -0.6992 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E01 mock treatment 429510.0 -7960.0 -0.04 396800.0 40700.0 0.24 0.1352 0.5628 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E02 mock treatment 565120.0 128000.0 0.72 458310.0 102000.0 0.59 0.9273 0.9954 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E03 compound treatment 567800.0 130000.0 0.73 423070.0 67000.0 0.39 0.7934 0.9558 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E04 compound treatment 499710.0 62200.0 0.35 542360.0 186000.0 1.08 1.0116 0.8908 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E05 compound treatment 406450.0 -31000.0 -0.17 318280.0 -37800.0 -0.22 -0.2786 -0.9936 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E06 compound treatment 302410.0 -135000.0 -0.76 386930.0 30800.0 0.18 -0.4112 -0.5265 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E07 compound treatment 527220.0 89700.0 0.51 296880.0 -59200.0 -0.34 0.1144 0.1872 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E08 compound treatment 404000.0 -33500.0 -0.19 496350.0 140000.0 0.81 0.4419 0.5293 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E09 mock treatment 534790.0 97300.0 0.55 342210.0 -13900.0 -0.08 0.3304 0.5967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E10 mock treatment 537130.0 99700.0 0.56 432590.0 76500.0 0.44 0.7104 0.9932 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E11 compound treatment 555220.0 118000.0 0.66 232960.0 -123000.0 -0.71 -0.0363 -0.0372 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E12 compound treatment 329950.0 -108000.0 -0.61 142950.0 -213000.0 -1.24 -1.3021 -0.946 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E13 compound treatment 360410.0 -77100.0 -0.43 283210.0 -72900.0 -0.42 -0.6057 -0.9999 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E14 compound treatment 576120.0 139000.0 0.78 351940.0 -4160.0 -0.02 0.5348 0.6849 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E15 compound treatment 249120.0 -188000.0 -1.06 312320.0 -43800.0 -0.25 -0.9293 -0.8523 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E16 compound treatment 576870.0 139000.0 0.78 416800.0 60700.0 0.35 0.8038 0.9346 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E17 mock treatment 517120.0 79600.0 0.45 290880.0 -65200.0 -0.38 0.0496 0.0845 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E18 mock treatment 526530.0 89100.0 0.5 382790.0 26700.0 0.15 0.4639 0.8842 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E19 compound treatment 457490.0 20000.0 0.11 374150.0 18000.0 0.1 0.1537 0.9993 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E20 compound treatment 483120.0 45600.0 0.26 366310.0 10200.0 0.06 0.2236 0.8478 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E21 compound treatment 382630.0 -54800.0 -0.31 331800.0 -24300.0 -0.14 -0.318 -0.9369 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E22 compound treatment 458990.0 21500.0 0.12 446740.0 90600.0 0.53 0.4573 0.8478 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E23 compound treatment 531570.0 94100.0 0.53 374010.0 17900.0 0.1 0.448 0.8299 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 E24 compound treatment 340160.0 -97300.0 -0.55 305850.0 -50300.0 -0.29 -0.5934 -0.9564 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F01 mock treatment 571070.0 134000.0 0.75 450240.0 94100.0 0.55 0.9178 0.9876 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F02 mock treatment 411780.0 -25700.0 -0.14 264640.0 -91500.0 -0.53 -0.4773 -0.8682 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F03 compound treatment 361160.0 -76300.0 -0.43 258210.0 -97900.0 -0.57 -0.7052 -0.9905 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F04 compound treatment 325700.0 -112000.0 -0.63 310190.0 -45900.0 -0.27 -0.6332 -0.9268 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F05 compound treatment 469460.0 32000.0 0.18 228730.0 -127000.0 -0.74 -0.395 -0.5195 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F06 compound treatment 293210.0 -144000.0 -0.81 440960.0 84900.0 0.49 -0.2263 -0.2383 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F07 compound treatment 489920.0 52400.0 0.3 210530.0 -146000.0 -0.84 -0.3882 -0.434 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F08 compound treatment 528730.0 91300.0 0.51 458660.0 103000.0 0.59 0.7838 0.9973 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F09 mock treatment 332230.0 -105000.0 -0.59 457760.0 102000.0 0.59 -0.0021 -0.0025 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F10 mock treatment 505360.0 67900.0 0.38 172160.0 -184000.0 -1.07 -0.4841 -0.4272 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F11 compound treatment 187520.0 -250000.0 -1.41 59060.0 -297000.0 -1.72 -2.2131 -0.995 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F12 compound treatment 264960.0 -173000.0 -0.97 202460.0 -154000.0 -0.89 -1.3168 -0.9991 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F13 compound treatment 229720.0 -208000.0 -1.17 306800.0 -49300.0 -0.29 -1.0292 -0.8548 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F14 compound treatment 460030.0 22600.0 0.13 351090.0 -5010.0 -0.03 0.0692 0.5314 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F15 compound treatment 423580.0 -13900.0 -0.08 389930.0 33800.0 0.2 0.0834 0.395 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F16 compound treatment 524000.0 86500.0 0.49 294910.0 -61200.0 -0.35 0.0935 0.1551 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F17 mock treatment 422850.0 -14600.0 -0.08 332880.0 -23200.0 -0.13 -0.1534 -0.9721 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F18 mock treatment 533720.0 96200.0 0.54 240800.0 -115000.0 -0.67 -0.0897 -0.1042 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F19 compound treatment 362680.0 -74800.0 -0.42 260400.0 -95700.0 -0.56 -0.6902 -0.9907 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F20 compound treatment 326130.0 -111000.0 -0.63 222950.0 -133000.0 -0.77 -0.9893 -0.9946 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F21 compound treatment 276390.0 -161000.0 -0.91 312660.0 -43400.0 -0.25 -0.8194 -0.8706 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F22 compound treatment 404060.0 -33400.0 -0.19 257760.0 -98300.0 -0.57 -0.5363 -0.893 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F23 compound treatment 365760.0 -71700.0 -0.4 198470.0 -158000.0 -0.91 -0.9319 -0.9325 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 F24 compound treatment 241050.0 -196000.0 -1.11 192700.0 -163000.0 -0.95 -1.452 -0.997 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G01 compound treatment 432160.0 -5310.0 -0.03 339800.0 -16300.0 -0.09 -0.088 -0.8874 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G02 compound treatment 309810.0 -128000.0 -0.72 281490.0 -74600.0 -0.43 -0.8142 -0.9705 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G03 mock treatment 429400.0 -8070.0 -0.05 463250.0 107000.0 0.62 0.4073 0.6537 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G04 mock treatment 547840.0 110000.0 0.62 464320.0 108000.0 0.63 0.8831 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G05 compound treatment 450890.0 13400.0 0.08 453220.0 97100.0 0.56 0.4517 0.7948 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G06 compound treatment 569530.0 132000.0 0.74 409400.0 53300.0 0.31 0.7442 0.9244 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G07 compound treatment 426920.0 -10600.0 -0.06 484910.0 129000.0 0.75 0.4862 0.6488 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G08 compound treatment 502240.0 64800.0 0.36 367930.0 11800.0 0.07 0.3063 0.8256 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G09 compound treatment 492550.0 55100.0 0.31 274920.0 -81200.0 -0.47 -0.1137 -0.2016 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G10 compound treatment 580610.0 143000.0 0.81 385950.0 29800.0 0.17 0.6922 0.8398 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G11 compound treatment 466330.0 28900.0 0.16 163140.0 -193000.0 -1.12 -0.6764 -0.5982 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G12 compound treatment 463150.0 25700.0 0.14 464400.0 108000.0 0.63 0.5463 0.8477 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G13 compound treatment 266740.0 -171000.0 -0.96 215320.0 -141000.0 -0.82 -1.257 -0.9967 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G14 compound treatment 246940.0 -191000.0 -1.07 420230.0 64100.0 0.37 -0.4955 -0.4364 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G15 compound treatment 152070.0 -285000.0 -1.61 110240.0 -246000.0 -1.43 -2.1443 -0.9982 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G16 compound treatment 327750.0 -110000.0 -0.62 454880.0 98800.0 0.57 -0.0317 -0.0376 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G17 compound treatment 428360.0 -9110.0 -0.05 429250.0 73100.0 0.42 0.2637 0.6171 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G18 compound treatment 266770.0 -171000.0 -0.96 442370.0 86300.0 0.5 -0.3257 -0.3007 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G19 mock treatment 376160.0 -61300.0 -0.35 245960.0 -110000.0 -0.64 -0.6957 -0.9582 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G20 mock treatment 353070.0 -84400.0 -0.48 329120.0 -27000.0 -0.16 -0.4466 -0.8928 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G21 compound treatment 346750.0 -90700.0 -0.51 345990.0 -10100.0 -0.06 -0.4026 -0.7832 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G22 compound treatment 417440.0 -20000.0 -0.11 309330.0 -46800.0 -0.27 -0.2715 -0.9244 3071255 BCB03_000457 NC(=N)NCC#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G23 compound treatment 376820.0 -60700.0 -0.34 339970.0 -16100.0 -0.09 -0.3076 -0.8689 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 G24 compound treatment 514780.0 77300.0 0.44 327800.0 -28300.0 -0.16 0.1917 0.4121 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H01 compound treatment 355590.0 -81900.0 -0.46 142000.0 -214000.0 -1.24 -1.2039 -0.909 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H02 compound treatment 515970.0 78500.0 0.44 172500.0 -184000.0 -1.06 -0.4404 -0.382 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H03 mock treatment 274980.0 -162000.0 -0.91 416560.0 60500.0 0.35 -0.3989 -0.4072 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H04 mock treatment 233730.0 -204000.0 -1.15 275840.0 -80300.0 -0.47 -1.1402 -0.9211 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H05 compound treatment 477970.0 40500.0 0.23 182640.0 -173000.0 -1.01 -0.5501 -0.5333 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H06 compound treatment 347420.0 -90100.0 -0.51 373090.0 17000.0 0.1 -0.2888 -0.5592 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H07 compound treatment 261550.0 -176000.0 -0.99 425570.0 69500.0 0.4 -0.4154 -0.3885 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H08 compound treatment 336600.0 -101000.0 -0.57 446670.0 90600.0 0.53 -0.0301 -0.039 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H09 compound treatment 9340.0 -428000.0 -2.41 9440.0 -347000.0 -2.01 -3.1259 -0.9959 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H10 compound treatment 434140.0 -3330.0 -0.02 471940.0 116000.0 0.67 0.4618 0.6871 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H11 compound treatment 247540.0 -190000.0 -1.07 256920.0 -99200.0 -0.58 -1.1628 -0.9577 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H12 compound treatment 554790.0 117000.0 0.66 447140.0 91000.0 0.53 0.8403 0.9938 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H13 compound treatment 222080.0 -215000.0 -1.21 302940.0 -53200.0 -0.31 -1.0754 -0.8596 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H14 compound treatment 380480.0 -57000.0 -0.32 335200.0 -20900.0 -0.12 -0.3126 -0.9114 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H15 compound treatment 484530.0 47100.0 0.26 248970.0 -107000.0 -0.62 -0.252 -0.3731 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H16 compound treatment 321490.0 -116000.0 -0.65 323860.0 -32200.0 -0.19 -0.5939 -0.8745 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H17 compound treatment 494880.0 57400.0 0.32 359160.0 3060.0 0.02 0.2411 0.7448 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H18 compound treatment 462310.0 24800.0 0.14 462530.0 106000.0 0.62 0.5353 0.8459 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H19 mock treatment 403890.0 -33600.0 -0.19 373830.0 17700.0 0.1 -0.061 -0.2834 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H20 mock treatment 492970.0 55500.0 0.31 346340.0 -9760.0 -0.06 0.1809 0.5697 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H21 compound treatment 340380.0 -97100.0 -0.55 163650.0 -192000.0 -1.12 -1.1757 -0.946 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H22 compound treatment 424720.0 -12800.0 -0.07 235950.0 -120000.0 -0.7 -0.5435 -0.7758 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H23 compound treatment 363420.0 -74100.0 -0.42 309340.0 -46800.0 -0.27 -0.4865 -0.9783 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 H24 compound treatment 310720.0 -127000.0 -0.71 268160.0 -87900.0 -0.51 -0.8652 -0.9864 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I01 compound treatment 449080.0 11600.0 0.07 497650.0 142000.0 0.82 0.6267 0.761 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I02 compound treatment 507370.0 69900.0 0.39 310740.0 -45400.0 -0.26 0.0922 0.1948 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I03 compound treatment 299610.0 -138000.0 -0.78 207360.0 -149000.0 -0.86 -1.1588 -0.9986 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I04 compound treatment 286880.0 -151000.0 -0.85 253560.0 -103000.0 -0.59 -1.02 -0.985 1035256 BCB03_000483 C#CCNCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I05 mock treatment 238510.0 -199000.0 -1.12 278950.0 -77200.0 -0.45 -1.1084 -0.919 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I06 mock treatment 434630.0 -2840.0 -0.02 274120.0 -82000.0 -0.48 -0.3475 -0.7305 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I07 compound treatment 514290.0 76800.0 0.43 163160.0 -193000.0 -1.12 -0.4854 -0.4047 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I08 compound treatment 345700.0 -91800.0 -0.52 265710.0 -90400.0 -0.52 -0.736 -1.0 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I09 compound treatment 190130.0 -247000.0 -1.39 203930.0 -152000.0 -0.88 -1.6086 -0.9758 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I10 compound treatment 361720.0 -75800.0 -0.43 523520.0 167000.0 0.97 0.385 0.3631 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I11 compound treatment 326760.0 -111000.0 -0.62 191490.0 -165000.0 -0.95 -1.1158 -0.9786 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I12 compound treatment 464960.0 27500.0 0.15 278640.0 -77500.0 -0.45 -0.2082 -0.4383 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I13 compound treatment 322950.0 -115000.0 -0.64 354620.0 -1480.0 -0.01 -0.462 -0.7165 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I14 compound treatment 374880.0 -62600.0 -0.35 205390.0 -151000.0 -0.87 -0.8672 -0.9202 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I15 compound treatment 350570.0 -86900.0 -0.49 225480.0 -131000.0 -0.76 -0.8816 -0.9776 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I16 compound treatment 269570.0 -168000.0 -0.95 245410.0 -111000.0 -0.64 -1.1223 -0.9822 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I17 compound treatment 449120.0 11600.0 0.07 412900.0 56800.0 0.33 0.2793 0.8316 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I18 compound treatment 563680.0 126000.0 0.71 353980.0 -2120.0 -0.01 0.4937 0.6947 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I19 compound treatment 286950.0 -151000.0 -0.85 405730.0 49600.0 0.29 -0.3957 -0.4421 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I20 compound treatment 272880.0 -165000.0 -0.93 296480.0 -59600.0 -0.35 -0.8997 -0.9097 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I21 mock treatment 524530.0 87100.0 0.49 279770.0 -76300.0 -0.44 0.0335 0.0508 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I22 mock treatment 362670.0 -74800.0 -0.42 404200.0 48100.0 0.28 -0.1005 -0.199 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I23 compound treatment 327720.0 -110000.0 -0.62 328170.0 -27900.0 -0.16 -0.5514 -0.8633 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 I24 compound treatment 295770.0 -142000.0 -0.8 542330.0 186000.0 1.08 0.1996 0.1487 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J01 compound treatment 267520.0 -170000.0 -0.96 129300.0 -227000.0 -1.32 -1.6066 -0.9878 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J02 compound treatment 526730.0 89300.0 0.5 330930.0 -25200.0 -0.15 0.2521 0.4817 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J03 compound treatment 467200.0 29700.0 0.17 320660.0 -35400.0 -0.21 -0.027 -0.1019 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J04 compound treatment 344560.0 -92900.0 -0.52 135270.0 -221000.0 -1.28 -1.2754 -0.922 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J05 mock treatment 272580.0 -165000.0 -0.93 163170.0 -193000.0 -1.12 -1.4476 -0.9957 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J06 mock treatment 208130.0 -229000.0 -1.29 359560.0 3460.0 0.02 -0.8988 -0.696 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J07 compound treatment 413310.0 -24200.0 -0.14 183850.0 -172000.0 -1.0 -0.8026 -0.796 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J08 compound treatment 294500.0 -143000.0 -0.8 239720.0 -116000.0 -0.67 -1.0464 -0.9962 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J09 compound treatment 492260.0 54800.0 0.31 200720.0 -155000.0 -0.9 -0.4191 -0.44 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J10 compound treatment 342730.0 -94700.0 -0.53 270740.0 -85400.0 -0.5 -0.7272 -0.9993 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J11 compound treatment 435260.0 -2210.0 -0.01 454900.0 98800.0 0.57 0.3963 0.6916 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J12 compound treatment 359200.0 -78300.0 -0.44 303450.0 -52700.0 -0.31 -0.5275 -0.984 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J13 compound treatment 272650.0 -165000.0 -0.93 230460.0 -126000.0 -0.73 -1.1713 -0.9928 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J14 compound treatment 428340.0 -9130.0 -0.05 347240.0 -8860.0 -0.05 -0.0727 -1.0 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J15 compound treatment 131470.0 -306000.0 -1.72 116480.0 -240000.0 -1.39 -2.2007 -0.9943 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J16 compound treatment 327090.0 -110000.0 -0.62 328320.0 -27800.0 -0.16 -0.5533 -0.862 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J17 compound treatment 283260.0 -154000.0 -0.87 272990.0 -83100.0 -0.48 -0.9547 -0.9615 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J18 compound treatment 376230.0 -61200.0 -0.34 401370.0 45300.0 0.26 -0.0582 -0.1342 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J19 compound treatment 152480.0 -285000.0 -1.6 177440.0 -179000.0 -1.04 -1.8671 -0.9776 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J20 compound treatment 409340.0 -28100.0 -0.16 328830.0 -27300.0 -0.16 -0.2238 -1.0 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J21 mock treatment 298340.0 -139000.0 -0.78 423260.0 67200.0 0.39 -0.2784 -0.3183 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J22 mock treatment 457800.0 20300.0 0.11 401220.0 45100.0 0.26 0.2659 0.9312 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J23 compound treatment 320660.0 -117000.0 -0.66 298620.0 -57500.0 -0.33 -0.7007 -0.9504 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 J24 compound treatment 382240.0 -55200.0 -0.31 288520.0 -67600.0 -0.39 -0.497 -0.9934 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K01 compound treatment 200400.0 -237000.0 -1.33 206610.0 -149000.0 -0.87 -1.5567 -0.9782 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K02 compound treatment 487920.0 50400.0 0.28 529920.0 174000.0 1.01 0.9136 0.8724 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K03 compound treatment 537440.0 100000.0 0.56 280210.0 -75900.0 -0.44 0.0867 0.1214 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K04 compound treatment 459710.0 22200.0 0.13 498560.0 142000.0 0.83 0.6727 0.8051 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K05 compound treatment 191530.0 -246000.0 -1.38 218720.0 -137000.0 -0.8 -1.5424 -0.9656 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K06 compound treatment 393130.0 -44300.0 -0.25 379310.0 23200.0 0.13 -0.0813 -0.2868 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K07 mock treatment 568800.0 131000.0 0.74 382560.0 26500.0 0.15 0.6313 0.836 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K08 mock treatment 210820.0 -227000.0 -1.28 540740.0 185000.0 1.07 -0.1451 -0.0871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K09 compound treatment 512740.0 75300.0 0.42 236320.0 -120000.0 -0.69 -0.1916 -0.2355 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K10 compound treatment 301180.0 -136000.0 -0.77 206560.0 -150000.0 -0.87 -1.1558 -0.9981 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K11 compound treatment 304910.0 -133000.0 -0.75 261360.0 -94700.0 -0.55 -0.9162 -0.9887 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K12 compound treatment 327570.0 -110000.0 -0.62 263130.0 -93000.0 -0.54 -0.8187 -0.9977 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K13 compound treatment 206100.0 -231000.0 -1.3 178340.0 -178000.0 -1.03 -1.65 -0.9933 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K14 compound treatment 495910.0 58400.0 0.33 450660.0 94600.0 0.55 0.6204 0.9701 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K15 mock treatment 493780.0 56300.0 0.32 477170.0 121000.0 0.7 0.7206 0.9354 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K16 mock treatment 435760.0 -1710.0 -0.01 377700.0 21600.0 0.13 0.0818 0.6508 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K17 compound treatment 418500.0 -19000.0 -0.11 488900.0 133000.0 0.77 0.4691 0.6033 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K18 compound treatment 395770.0 -41700.0 -0.23 455840.0 99700.0 0.58 0.243 0.3893 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K19 compound treatment 390410.0 -47100.0 -0.26 331590.0 -24500.0 -0.14 -0.2879 -0.9574 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K20 compound treatment 529140.0 91700.0 0.52 398480.0 42400.0 0.25 0.5387 0.9424 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K21 compound treatment 364380.0 -73100.0 -0.41 233240.0 -123000.0 -0.71 -0.7948 -0.9659 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K22 compound treatment 341240.0 -96200.0 -0.54 377390.0 21300.0 0.12 -0.2958 -0.5323 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K23 mock treatment 577860.0 140000.0 0.79 429220.0 73100.0 0.42 0.8587 0.9574 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 K24 mock treatment 362100.0 -75400.0 -0.42 325010.0 -31100.0 -0.18 -0.4275 -0.9274 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L01 compound treatment 322880.0 -115000.0 -0.65 196000.0 -160000.0 -0.93 -1.1127 -0.9842 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L02 compound treatment 481160.0 43700.0 0.25 359250.0 3150.0 0.02 0.1868 0.7575 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L03 compound treatment 263060.0 -174000.0 -0.98 321080.0 -35000.0 -0.2 -0.8379 -0.8357 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L04 compound treatment 221140.0 -216000.0 -1.22 451040.0 94900.0 0.55 -0.4718 -0.353 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L05 compound treatment 327040.0 -110000.0 -0.62 450760.0 94700.0 0.55 -0.0514 -0.062 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L06 compound treatment 400730.0 -36700.0 -0.21 324640.0 -31500.0 -0.18 -0.2753 -0.998 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L07 mock treatment 374400.0 -63100.0 -0.36 431040.0 74900.0 0.43 0.0562 0.1002 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L08 mock treatment 326690.0 -111000.0 -0.62 173280.0 -183000.0 -1.06 -1.1907 -0.968 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L09 compound treatment 603860.0 166000.0 0.94 368560.0 12500.0 0.07 0.7134 0.7594 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L10 compound treatment 302720.0 -135000.0 -0.76 339220.0 -16900.0 -0.1 -0.6056 -0.7918 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L11 compound treatment 310330.0 -127000.0 -0.72 265720.0 -90400.0 -0.52 -0.8768 -0.9883 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L12 compound treatment 200540.0 -237000.0 -1.33 275810.0 -80300.0 -0.47 -1.2724 -0.9007 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L13 compound treatment 328490.0 -109000.0 -0.61 275680.0 -80400.0 -0.47 -0.7636 -0.9909 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L14 compound treatment 554800.0 117000.0 0.66 288250.0 -67900.0 -0.39 0.1888 0.2456 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L15 mock treatment 419420.0 -18100.0 -0.1 405440.0 49300.0 0.29 0.1305 0.4297 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L16 mock treatment 477810.0 40300.0 0.23 339870.0 -16200.0 -0.09 0.094 0.3824 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L17 compound treatment 515580.0 78100.0 0.44 371730.0 15600.0 0.09 0.375 0.8353 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L18 compound treatment 424000.0 -13500.0 -0.08 362590.0 6490.0 0.04 -0.027 -0.3193 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L19 compound treatment 457340.0 19900.0 0.11 266810.0 -89300.0 -0.52 -0.2871 -0.5419 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L20 compound treatment 365440.0 -72000.0 -0.41 262240.0 -93900.0 -0.54 -0.6717 -0.9895 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L21 compound treatment 213730.0 -224000.0 -1.26 212260.0 -144000.0 -0.83 -1.4805 -0.98 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L22 compound treatment 387160.0 -50300.0 -0.28 358510.0 2410.0 0.01 -0.1904 -0.6715 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L23 mock treatment 377060.0 -60400.0 -0.34 232640.0 -123000.0 -0.72 -0.7468 -0.9421 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 L24 mock treatment 306990.0 -130000.0 -0.73 346560.0 -9540.0 -0.06 -0.5585 -0.7582 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M01 compound treatment 530510.0 93000.0 0.52 419520.0 63400.0 0.37 0.6304 0.985 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M02 compound treatment 447900.0 10400.0 0.06 444610.0 88500.0 0.51 0.4045 0.7829 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M03 compound treatment 282890.0 -155000.0 -0.87 433250.0 77100.0 0.45 -0.299 -0.3055 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M04 compound treatment 530940.0 93500.0 0.53 390590.0 34500.0 0.2 0.5135 0.9122 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M05 compound treatment 407890.0 -29600.0 -0.17 370100.0 14000.0 0.08 -0.0604 -0.3258 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M06 compound treatment 487550.0 50100.0 0.28 479610.0 124000.0 0.72 0.7058 0.917 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M07 compound treatment 384500.0 -53000.0 -0.3 413760.0 57700.0 0.33 0.0256 0.0571 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M08 compound treatment 380990.0 -56500.0 -0.32 428090.0 72000.0 0.42 0.0704 0.1341 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M09 mock treatment 351580.0 -85900.0 -0.48 501000.0 145000.0 0.84 0.2523 0.2602 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M10 mock treatment 351490.0 -86000.0 -0.48 334610.0 -21500.0 -0.12 -0.4304 -0.8611 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M11 compound treatment 239800.0 -198000.0 -1.11 531360.0 175000.0 1.02 -0.0682 -0.0452 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M12 compound treatment 567320.0 130000.0 0.73 334120.0 -22000.0 -0.13 0.4267 0.5751 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M13 mock treatment 496000.0 58500.0 0.33 420090.0 64000.0 0.37 0.4954 0.9982 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M14 mock treatment 598960.0 161000.0 0.91 259320.0 -96800.0 -0.56 0.2459 0.2302 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M15 compound treatment 442110.0 4640.0 0.03 396960.0 40900.0 0.24 0.186 0.7803 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M16 compound treatment 561160.0 124000.0 0.7 290010.0 -66100.0 -0.38 0.2213 0.2785 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M17 compound treatment 581790.0 144000.0 0.81 444640.0 88500.0 0.51 0.9376 0.9755 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M18 compound treatment 602210.0 165000.0 0.93 382620.0 26500.0 0.15 0.7645 0.8133 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M19 compound treatment 348800.0 -88700.0 -0.5 338240.0 -17900.0 -0.1 -0.4262 -0.836 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M20 compound treatment 452390.0 14900.0 0.08 278560.0 -77500.0 -0.45 -0.2586 -0.5653 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M21 compound treatment 311460.0 -126000.0 -0.71 359170.0 3070.0 0.02 -0.489 -0.6892 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M22 compound treatment 522370.0 84900.0 0.48 298810.0 -57300.0 -0.33 0.103 0.177 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M23 compound treatment 361500.0 -76000.0 -0.43 278750.0 -77400.0 -0.45 -0.6196 -0.9997 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 M24 compound treatment 311650.0 -126000.0 -0.71 329820.0 -26300.0 -0.15 -0.6086 -0.84 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N01 compound treatment 419250.0 -18200.0 -0.1 435600.0 79500.0 0.46 0.2535 0.5367 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N02 compound treatment 404390.0 -33100.0 -0.19 269370.0 -86700.0 -0.5 -0.4874 -0.9086 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N03 compound treatment 377540.0 -59900.0 -0.34 405340.0 49200.0 0.29 -0.0367 -0.0829 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N04 compound treatment 529640.0 92200.0 0.52 210780.0 -145000.0 -0.84 -0.2291 -0.2314 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N05 compound treatment 463380.0 25900.0 0.15 371840.0 15700.0 0.09 0.1677 0.9745 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N06 compound treatment 202740.0 -235000.0 -1.32 74300.0 -282000.0 -1.63 -2.09 -0.9944 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N07 compound treatment 387750.0 -49700.0 -0.28 146930.0 -209000.0 -1.21 -1.0557 -0.848 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N08 compound treatment 363200.0 -74300.0 -0.42 211330.0 -145000.0 -0.84 -0.8893 -0.9482 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N09 mock treatment 576080.0 139000.0 0.78 295330.0 -60800.0 -0.35 0.3025 0.3533 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N10 mock treatment 469120.0 31600.0 0.18 356220.0 116.0 0.0 0.1265 0.7098 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N11 compound treatment 209990.0 -227000.0 -1.28 190050.0 -166000.0 -0.96 -1.5865 -0.9901 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N12 compound treatment 170080.0 -267000.0 -1.51 106960.0 -249000.0 -1.44 -2.0861 -0.9998 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N13 mock treatment 559750.0 122000.0 0.69 313940.0 -42200.0 -0.24 0.3138 0.4296 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N14 mock treatment 420010.0 -17500.0 -0.1 348080.0 -8020.0 -0.05 -0.1024 -0.9417 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N15 compound treatment 319060.0 -118000.0 -0.67 182970.0 -173000.0 -1.0 -1.1813 -0.9802 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N16 compound treatment 168520.0 -269000.0 -1.51 152570.0 -204000.0 -1.18 -1.9053 -0.9924 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N17 compound treatment 239760.0 -198000.0 -1.11 169210.0 -187000.0 -1.08 -1.5534 -0.9999 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N18 compound treatment 234820.0 -203000.0 -1.14 41060.0 -315000.0 -1.83 -2.0986 -0.9743 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N19 compound treatment 443200.0 5730.0 0.03 126820.0 -229000.0 -1.33 -0.9174 -0.6898 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N20 compound treatment 105500.0 -332000.0 -1.87 67200.0 -289000.0 -1.68 -2.5062 -0.9985 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N21 compound treatment 328930.0 -109000.0 -0.61 189820.0 -166000.0 -0.96 -1.114 -0.9758 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N22 compound treatment 250310.0 -187000.0 -1.05 216180.0 -140000.0 -0.81 -1.3188 -0.9917 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N23 compound treatment 367260.0 -70200.0 -0.4 369400.0 13300.0 0.08 -0.225 -0.5586 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 N24 compound treatment 344480.0 -93000.0 -0.52 272660.0 -83400.0 -0.48 -0.7124 -0.9992 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O01 compound treatment 236340.0 -201000.0 -1.13 442880.0 86800.0 0.5 -0.4448 -0.359 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O02 compound treatment 588690.0 151000.0 0.85 397700.0 41600.0 0.24 0.7725 0.8731 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O03 compound treatment 457370.0 19900.0 0.11 372230.0 16100.0 0.09 0.1453 0.996 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O04 compound treatment 201710.0 -236000.0 -1.33 509690.0 154000.0 0.89 -0.3087 -0.1931 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O05 compound treatment 562890.0 125000.0 0.71 483010.0 127000.0 0.74 1.0197 0.9998 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O06 compound treatment 550670.0 113000.0 0.64 430690.0 74600.0 0.43 0.7565 0.9822 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O07 compound treatment 564890.0 127000.0 0.72 453810.0 97700.0 0.57 0.9079 0.9932 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O08 compound treatment 510490.0 73000.0 0.41 441090.0 85000.0 0.49 0.6392 0.9959 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O09 compound treatment 590020.0 153000.0 0.86 287420.0 -68700.0 -0.4 0.3256 0.3439 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O10 compound treatment 436440.0 -1030.0 -0.01 186340.0 -170000.0 -0.98 -0.7003 -0.7113 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O11 mock treatment 613030.0 176000.0 0.99 306340.0 -49800.0 -0.29 0.4948 0.4805 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O12 mock treatment 589540.0 152000.0 0.86 316200.0 -39900.0 -0.23 0.4417 0.4981 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O13 compound treatment 605680.0 168000.0 0.95 498470.0 142000.0 0.83 1.2534 0.9977 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O14 compound treatment 236090.0 -201000.0 -1.13 289400.0 -66700.0 -0.39 -1.0752 -0.8976 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O15 compound treatment 539430.0 102000.0 0.57 353280.0 -2820.0 -0.02 0.3943 0.6866 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O16 compound treatment 354280.0 -83200.0 -0.47 518530.0 162000.0 0.94 0.3349 0.3184 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O17 compound treatment 625640.0 188000.0 1.06 483600.0 127000.0 0.74 1.2719 0.9845 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O18 compound treatment 335200.0 -102000.0 -0.58 348610.0 -7490.0 -0.04 -0.4378 -0.7583 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O19 compound treatment 309250.0 -128000.0 -0.72 449760.0 93700.0 0.54 -0.1263 -0.1399 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O20 compound treatment 517180.0 79700.0 0.45 427360.0 71300.0 0.41 0.6095 0.9992 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O21 compound treatment 323680.0 -114000.0 -0.64 216660.0 -139000.0 -0.81 -1.0248 -0.9933 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O22 compound treatment 440930.0 3460.0 0.02 416000.0 59900.0 0.35 0.2594 0.7456 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O23 compound treatment 406180.0 -31300.0 -0.18 460700.0 105000.0 0.61 0.3044 0.4819 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 O24 compound treatment 403800.0 -33700.0 -0.19 449120.0 93000.0 0.54 0.2474 0.4327 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P01 compound treatment 307330.0 -130000.0 -0.73 354010.0 -2090.0 -0.01 -0.5266 -0.7187 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P02 compound treatment 232850.0 -205000.0 -1.15 155130.0 -201000.0 -1.17 -1.6387 -1.0 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P03 compound treatment 316870.0 -121000.0 -0.68 351910.0 -4190.0 -0.02 -0.4973 -0.732 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P04 compound treatment 425380.0 -12100.0 -0.07 182640.0 -173000.0 -1.01 -0.7595 -0.7532 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P05 compound treatment 374660.0 -62800.0 -0.35 238880.0 -117000.0 -0.68 -0.7307 -0.9536 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P06 compound treatment 252100.0 -185000.0 -1.04 180690.0 -175000.0 -1.02 -1.4572 -0.9999 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P07 compound treatment 157060.0 -280000.0 -1.58 115040.0 -241000.0 -1.4 -2.1048 -0.9982 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P08 compound treatment 249930.0 -188000.0 -1.06 141570.0 -215000.0 -1.24 -1.6263 -0.9967 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P09 compound treatment 182490.0 -255000.0 -1.44 155840.0 -200000.0 -1.16 -1.8362 -0.9945 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P10 compound treatment 299570.0 -138000.0 -0.78 360340.0 4240.0 0.02 -0.5316 -0.6844 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P11 mock treatment 292250.0 -145000.0 -0.82 423200.0 67100.0 0.39 -0.3029 -0.3346 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P12 mock treatment 341880.0 -95600.0 -0.54 236050.0 -120000.0 -0.7 -0.8728 -0.9919 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P13 compound treatment 248400.0 -189000.0 -1.06 115110.0 -241000.0 -1.4 -1.7409 -0.991 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P14 compound treatment 214650.0 -223000.0 -1.25 165640.0 -190000.0 -1.1 -1.668 -0.998 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P15 compound treatment 286560.0 -151000.0 -0.85 195700.0 -160000.0 -0.93 -1.2585 -0.999 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P16 compound treatment 239250.0 -198000.0 -1.12 336340.0 -19800.0 -0.11 -0.8701 -0.7757 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P17 compound treatment 216110.0 -221000.0 -1.25 191040.0 -165000.0 -0.96 -1.5581 -0.9915 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P18 compound treatment 392160.0 -45300.0 -0.26 367570.0 11500.0 0.07 -0.1333 -0.5059 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P19 compound treatment 242090.0 -195000.0 -1.1 270990.0 -85100.0 -0.49 -1.1268 -0.9346 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P20 compound treatment 287000.0 -150000.0 -0.85 277620.0 -78500.0 -0.46 -0.9208 -0.9576 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P21 compound treatment 263450.0 -174000.0 -0.98 122350.0 -234000.0 -1.36 -1.6513 -0.9873 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P22 compound treatment 343480.0 -94000.0 -0.53 281480.0 -74600.0 -0.43 -0.6802 -0.995 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P23 compound treatment 188960.0 -249000.0 -1.4 221010.0 -135000.0 -0.78 -1.5432 -0.9625 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2282 P24 compound treatment 439750.0 2280.0 0.01 304000.0 -52100.0 -0.3 -0.2046 -0.6765 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A01 compound treatment 467390.0 24100.0 0.14 516380.0 100000.0 0.58 0.5068 0.8495 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A02 compound treatment 174780.0 -268000.0 -1.51 233560.0 -183000.0 -1.06 -1.8177 -0.9849 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A03 compound treatment 236180.0 -207000.0 -1.17 251150.0 -165000.0 -0.96 -1.5012 -0.9952 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A04 compound treatment 262430.0 -181000.0 -1.02 426400.0 10200.0 0.06 -0.678 -0.6649 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A05 compound treatment 480160.0 36900.0 0.21 505090.0 88900.0 0.52 0.5114 0.9202 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A06 compound treatment 283380.0 -160000.0 -0.9 352970.0 -63200.0 -0.37 -0.8958 -0.9217 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A07 compound treatment 490340.0 47100.0 0.27 494510.0 78300.0 0.45 0.5085 0.9671 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A08 compound treatment 241450.0 -202000.0 -1.14 262730.0 -153000.0 -0.89 -1.4327 -0.9927 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A09 compound treatment 302580.0 -141000.0 -0.79 257830.0 -158000.0 -0.92 -1.2095 -0.9973 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A10 compound treatment 183250.0 -260000.0 -1.46 274730.0 -141000.0 -0.82 -1.6152 -0.9626 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A11 compound treatment 272800.0 -170000.0 -0.96 350520.0 -65700.0 -0.38 -0.9479 -0.9181 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A12 compound treatment 355120.0 -88100.0 -0.5 255150.0 -161000.0 -0.93 -1.0113 -0.9562 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A13 mock treatment 554410.0 111000.0 0.63 374490.0 -41700.0 -0.24 0.2714 0.4045 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A14 mock treatment 419450.0 -23800.0 -0.13 268740.0 -147000.0 -0.86 -0.6995 -0.8081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A15 compound treatment 236760.0 -207000.0 -1.16 287110.0 -129000.0 -0.75 -1.3514 -0.9774 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A16 compound treatment 353500.0 -89800.0 -0.51 259100.0 -157000.0 -0.91 -1.0016 -0.9613 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A17 compound treatment 301400.0 -142000.0 -0.8 426880.0 10700.0 0.06 -0.5209 -0.6504 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A18 compound treatment 452960.0 9700.0 0.05 390400.0 -25800.0 -0.15 -0.0672 -0.4219 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A19 compound treatment 356810.0 -86500.0 -0.49 227520.0 -189000.0 -1.09 -1.1179 -0.9334 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A20 compound treatment 514960.0 71700.0 0.4 329620.0 -86600.0 -0.5 -0.0697 -0.1081 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A21 compound treatment 332320.0 -111000.0 -0.62 272110.0 -144000.0 -0.84 -1.0325 -0.9897 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A22 compound treatment 507540.0 64300.0 0.36 356410.0 -59800.0 -0.35 0.0107 0.0213 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A23 compound treatment 362360.0 -80900.0 -0.46 260190.0 -156000.0 -0.9 -0.9618 -0.9495 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 A24 compound treatment 214960.0 -228000.0 -1.29 445630.0 29400.0 0.17 -0.7881 -0.6079 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B01 compound treatment 486470.0 43200.0 0.24 446350.0 30100.0 0.17 0.2956 0.9869 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B02 compound treatment 556450.0 113000.0 0.64 454100.0 37900.0 0.22 0.606 0.899 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B03 compound treatment 318400.0 -125000.0 -0.7 184500.0 -232000.0 -1.34 -1.4472 -0.9543 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B04 compound treatment 449020.0 5760.0 0.03 542920.0 127000.0 0.73 0.5426 0.7376 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B05 compound treatment 432700.0 -10600.0 -0.06 499360.0 83200.0 0.48 0.299 0.6153 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B06 compound treatment 426050.0 -17200.0 -0.1 314440.0 -102000.0 -0.59 -0.4858 -0.8123 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B07 compound treatment 451290.0 8030.0 0.05 417820.0 1610.0 0.01 0.0386 0.8357 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B08 compound treatment 371330.0 -71900.0 -0.4 445400.0 29200.0 0.17 -0.1666 -0.3796 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B09 compound treatment 584490.0 141000.0 0.8 441390.0 25200.0 0.15 0.6655 0.8232 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B10 compound treatment 130960.0 -312000.0 -1.76 104320.0 -312000.0 -1.81 -2.5222 -0.9999 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B11 compound treatment 419770.0 -23500.0 -0.13 526210.0 110000.0 0.64 0.3576 0.5489 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B12 compound treatment 257530.0 -186000.0 -1.05 230980.0 -185000.0 -1.07 -1.4989 -0.9999 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B13 mock treatment 474630.0 31400.0 0.18 517950.0 102000.0 0.59 0.5421 0.8802 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B14 mock treatment 519270.0 76000.0 0.43 507390.0 91200.0 0.53 0.6765 0.9945 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B15 compound treatment 332160.0 -111000.0 -0.63 389360.0 -26800.0 -0.16 -0.5524 -0.857 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B16 compound treatment 125990.0 -317000.0 -1.79 132160.0 -284000.0 -1.65 -2.4278 -0.9992 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B17 compound treatment 322820.0 -120000.0 -0.68 405710.0 -10500.0 -0.06 -0.5225 -0.7675 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B18 compound treatment 116450.0 -327000.0 -1.84 108210.0 -308000.0 -1.79 -2.564 -0.9999 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B19 compound treatment 420180.0 -23100.0 -0.13 462120.0 45900.0 0.27 0.0964 0.3254 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B20 compound treatment 183050.0 -260000.0 -1.46 149630.0 -267000.0 -1.55 -2.129 -0.9996 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B21 compound treatment 438670.0 -4590.0 -0.03 481160.0 65000.0 0.38 0.2481 0.6571 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B22 compound treatment 141570.0 -302000.0 -1.7 136820.0 -279000.0 -1.62 -2.3466 -0.9997 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B23 compound treatment 451320.0 8060.0 0.05 484550.0 68300.0 0.4 0.3123 0.7829 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 B24 compound treatment 169080.0 -274000.0 -1.54 124530.0 -292000.0 -1.69 -2.2875 -0.999 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C01 compound treatment 474680.0 31400.0 0.18 357140.0 -59100.0 -0.34 -0.1172 -0.3039 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C02 compound treatment 513380.0 70100.0 0.39 308260.0 -108000.0 -0.63 -0.1635 -0.221 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C03 compound treatment 396360.0 -46900.0 -0.26 215220.0 -201000.0 -1.17 -1.0109 -0.8458 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C04 compound treatment 507400.0 64100.0 0.36 210400.0 -206000.0 -1.19 -0.5887 -0.4721 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C05 compound treatment 482980.0 39700.0 0.22 408160.0 -8050.0 -0.05 0.1251 0.5477 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C06 compound treatment 464900.0 21600.0 0.12 352170.0 -64000.0 -0.37 -0.1765 -0.4515 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C07 compound treatment 411920.0 -31300.0 -0.18 281630.0 -135000.0 -0.78 -0.6766 -0.8456 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C08 compound treatment 380960.0 -62300.0 -0.35 307480.0 -109000.0 -0.63 -0.6939 -0.9617 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C09 compound treatment 491610.0 48300.0 0.27 472240.0 56000.0 0.32 0.4222 0.9961 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C10 compound treatment 298110.0 -145000.0 -0.82 316230.0 -100000.0 -0.58 -0.9878 -0.9859 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C11 mock treatment 412930.0 -30300.0 -0.17 397180.0 -19000.0 -0.11 -0.1988 -0.9777 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C12 mock treatment 289730.0 -154000.0 -0.86 404200.0 -12000.0 -0.07 -0.6604 -0.7616 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C13 compound treatment 23100.0 -420000.0 -2.37 12270.0 -404000.0 -2.34 -3.329 -1.0 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C14 compound treatment 379300.0 -64000.0 -0.36 340640.0 -75600.0 -0.44 -0.5645 -0.9952 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C15 mock treatment 436990.0 -6270.0 -0.04 315240.0 -101000.0 -0.59 -0.439 -0.7484 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C16 mock treatment 288870.0 -154000.0 -0.87 347290.0 -68900.0 -0.4 -0.8972 -0.9379 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C17 compound treatment 54570.0 -389000.0 -2.19 22880.0 -393000.0 -2.28 -3.1602 -0.9998 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C18 compound treatment 273860.0 -169000.0 -0.95 394600.0 -21600.0 -0.13 -0.7629 -0.7932 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C19 compound treatment 231710.0 -212000.0 -1.19 259950.0 -156000.0 -0.91 -1.4829 -0.9909 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C20 compound treatment 378970.0 -64300.0 -0.36 255450.0 -161000.0 -0.93 -0.9152 -0.9151 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C21 compound treatment 365630.0 -77600.0 -0.44 308520.0 -108000.0 -0.62 -0.7506 -0.9848 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C22 compound treatment 355120.0 -88100.0 -0.5 302690.0 -114000.0 -0.66 -0.8164 -0.9903 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C23 compound treatment 428640.0 -14600.0 -0.08 444040.0 27800.0 0.16 0.0559 0.3087 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 C24 compound treatment 342430.0 -101000.0 -0.57 342600.0 -73600.0 -0.43 -0.7032 -0.9901 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D01 compound treatment 533920.0 90700.0 0.51 297230.0 -119000.0 -0.69 -0.127 -0.148 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D02 compound treatment 82440.0 -361000.0 -2.03 47160.0 -369000.0 -2.14 -2.9497 -0.9997 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D03 compound treatment 512040.0 68800.0 0.39 305280.0 -111000.0 -0.64 -0.1811 -0.2412 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D04 compound treatment 219040.0 -224000.0 -1.26 180640.0 -236000.0 -1.37 -1.8586 -0.9992 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D05 compound treatment 455760.0 12500.0 0.07 286250.0 -130000.0 -0.75 -0.4832 -0.6383 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D06 compound treatment 127360.0 -316000.0 -1.78 157800.0 -258000.0 -1.5 -2.3172 -0.9964 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D07 compound treatment 477150.0 33900.0 0.19 268270.0 -148000.0 -0.86 -0.4718 -0.5368 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D08 compound treatment 238780.0 -204000.0 -1.15 209920.0 -206000.0 -1.2 -1.6599 -0.9998 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D09 compound treatment 520450.0 77200.0 0.43 389020.0 -27200.0 -0.16 0.1958 0.4235 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D10 compound treatment 268750.0 -175000.0 -0.98 306660.0 -110000.0 -0.64 -1.1439 -0.9777 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D11 mock treatment 532240.0 89000.0 0.5 595520.0 179000.0 1.04 1.0895 0.9439 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D12 mock treatment 434240.0 -9020.0 -0.05 593840.0 178000.0 1.03 0.6925 0.6714 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D13 compound treatment 482760.0 39500.0 0.22 489510.0 73300.0 0.43 0.4578 0.9543 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D14 compound treatment 185550.0 -258000.0 -1.45 143420.0 -273000.0 -1.58 -2.1445 -0.9991 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D15 mock treatment 541390.0 98100.0 0.55 353850.0 -62400.0 -0.36 0.1349 0.2043 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D16 mock treatment 541000.0 97700.0 0.55 386210.0 -30000.0 -0.17 0.2661 0.461 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D17 compound treatment 379310.0 -64000.0 -0.36 438810.0 22600.0 0.13 -0.1619 -0.4225 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D18 compound treatment 296170.0 -147000.0 -0.83 241760.0 -174000.0 -1.01 -1.3009 -0.9951 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D19 compound treatment 392800.0 -50500.0 -0.28 508670.0 92500.0 0.54 0.1783 0.2938 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D20 compound treatment 549940.0 107000.0 0.6 386910.0 -29300.0 -0.17 0.3045 0.4879 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D21 compound treatment 346810.0 -96500.0 -0.54 311270.0 -105000.0 -0.61 -0.8143 -0.9984 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D22 compound treatment 420500.0 -22800.0 -0.13 237000.0 -179000.0 -1.04 -0.8255 -0.7883 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D23 compound treatment 200710.0 -243000.0 -1.37 245320.0 -171000.0 -0.99 -1.6663 -0.9876 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 D24 compound treatment 27610.0 -416000.0 -2.34 9690.0 -407000.0 -2.36 -3.3216 -1.0 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E01 mock treatment 393810.0 -49500.0 -0.28 405600.0 -10600.0 -0.06 -0.2403 -0.843 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E02 mock treatment 440960.0 -2300.0 -0.01 316560.0 -99600.0 -0.58 -0.4178 -0.7228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E03 compound treatment 519910.0 76600.0 0.43 325290.0 -90900.0 -0.53 -0.0677 -0.0994 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E04 compound treatment 590530.0 147000.0 0.83 349170.0 -67000.0 -0.39 0.3113 0.34 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E05 compound treatment 407520.0 -35700.0 -0.2 252320.0 -164000.0 -0.95 -0.8143 -0.8382 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E06 compound treatment 400250.0 -43000.0 -0.24 294600.0 -122000.0 -0.71 -0.6699 -0.8984 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E07 compound treatment 504520.0 61300.0 0.34 435540.0 19300.0 0.11 0.3231 0.8911 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E08 compound treatment 497330.0 54100.0 0.3 529400.0 113000.0 0.66 0.6794 0.939 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E09 mock treatment 582730.0 139000.0 0.79 393280.0 -22900.0 -0.13 0.4612 0.5791 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E10 mock treatment 507900.0 64600.0 0.36 407860.0 -8350.0 -0.05 0.2231 0.6077 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E11 compound treatment 404090.0 -39200.0 -0.22 436800.0 20600.0 0.12 -0.0715 -0.285 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E12 compound treatment 287060.0 -156000.0 -0.88 197920.0 -218000.0 -1.27 -1.5169 -0.9841 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E13 compound treatment 375360.0 -67900.0 -0.38 330530.0 -85700.0 -0.5 -0.6216 -0.9916 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E14 compound treatment 226530.0 -217000.0 -1.22 191720.0 -224000.0 -1.3 -1.7833 -0.9995 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E15 compound treatment 322410.0 -121000.0 -0.68 382940.0 -33300.0 -0.19 -0.6175 -0.8732 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E16 compound treatment 170180.0 -273000.0 -1.54 183440.0 -233000.0 -1.35 -2.0416 -0.9979 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E17 mock treatment 390890.0 -52400.0 -0.29 329760.0 -86400.0 -0.5 -0.563 -0.968 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E18 mock treatment 271140.0 -172000.0 -0.97 355700.0 -60500.0 -0.35 -0.9333 -0.9056 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E19 compound treatment 455620.0 12400.0 0.07 313280.0 -103000.0 -0.6 -0.3729 -0.6205 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E20 compound treatment 347940.0 -95300.0 -0.54 381820.0 -34400.0 -0.2 -0.5205 -0.9091 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E21 compound treatment 342960.0 -100000.0 -0.56 284120.0 -132000.0 -0.77 -0.9409 -0.9887 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E22 compound treatment 395270.0 -48000.0 -0.27 261930.0 -154000.0 -0.89 -0.8237 -0.8813 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E23 compound treatment 336860.0 -106000.0 -0.6 313120.0 -103000.0 -0.6 -0.8463 -1.0 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 E24 compound treatment 516360.0 73100.0 0.41 471040.0 54800.0 0.32 0.5158 0.9919 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F01 mock treatment 554170.0 111000.0 0.62 514190.0 98000.0 0.57 0.8433 0.9989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F02 mock treatment 336930.0 -106000.0 -0.6 372730.0 -43500.0 -0.25 -0.6016 -0.9261 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F03 compound treatment 524700.0 81400.0 0.46 192640.0 -224000.0 -1.3 -0.5926 -0.4309 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F04 compound treatment 320250.0 -123000.0 -0.69 252350.0 -164000.0 -0.95 -1.1616 -0.9879 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F05 compound treatment 276480.0 -167000.0 -0.94 313530.0 -103000.0 -0.6 -1.085 -0.9759 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F06 compound treatment 489140.0 45900.0 0.26 411770.0 -4440.0 -0.03 0.1644 0.6335 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F07 compound treatment 249610.0 -194000.0 -1.09 211120.0 -205000.0 -1.19 -1.6119 -0.9991 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F08 compound treatment 465630.0 22400.0 0.13 477060.0 60900.0 0.35 0.3386 0.9036 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F09 mock treatment 471120.0 27900.0 0.16 374310.0 -41900.0 -0.24 -0.0609 -0.2106 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F10 mock treatment 421880.0 -21400.0 -0.12 564230.0 148000.0 0.86 0.5219 0.6021 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F11 compound treatment 338620.0 -105000.0 -0.59 491560.0 75400.0 0.44 -0.1075 -0.1466 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F12 compound treatment 394680.0 -48600.0 -0.27 495530.0 79300.0 0.46 0.1319 0.2465 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F13 compound treatment 467770.0 24500.0 0.14 613440.0 197000.0 1.14 0.9064 0.7867 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F14 compound treatment 263420.0 -180000.0 -1.01 321210.0 -95000.0 -0.55 -1.1055 -0.9591 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F15 compound treatment 479090.0 35800.0 0.2 304250.0 -112000.0 -0.65 -0.3165 -0.4655 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F16 compound treatment 189170.0 -254000.0 -1.43 131590.0 -285000.0 -1.65 -2.1786 -0.9975 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F17 mock treatment 389560.0 -53700.0 -0.3 407410.0 -8800.0 -0.05 -0.2498 -0.8149 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F18 mock treatment 439840.0 -3420.0 -0.02 421630.0 5420.0 0.03 0.0086 0.2338 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F19 compound treatment 472090.0 28800.0 0.16 306600.0 -110000.0 -0.64 -0.3347 -0.5102 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F20 compound treatment 367680.0 -75600.0 -0.43 423840.0 7630.0 0.04 -0.2696 -0.6301 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F21 compound treatment 535460.0 92200.0 0.52 393200.0 -23000.0 -0.13 0.2727 0.5088 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F22 compound treatment 351240.0 -92000.0 -0.52 370500.0 -45700.0 -0.27 -0.5537 -0.9516 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F23 compound treatment 422760.0 -20500.0 -0.12 225710.0 -190000.0 -1.1 -0.8628 -0.7767 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 F24 compound treatment 300750.0 -143000.0 -0.8 454330.0 38100.0 0.22 -0.411 -0.4938 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G01 compound treatment 521600.0 78300.0 0.44 314140.0 -102000.0 -0.59 -0.1067 -0.1446 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G02 compound treatment 577470.0 134000.0 0.76 364260.0 -51900.0 -0.3 0.3212 0.3949 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G03 mock treatment 536380.0 93100.0 0.52 353880.0 -62300.0 -0.36 0.1151 0.1807 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G04 mock treatment 542240.0 99000.0 0.56 407380.0 -8830.0 -0.05 0.3578 0.6394 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G05 compound treatment 279940.0 -163000.0 -0.92 466420.0 50200.0 0.29 -0.4442 -0.4606 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G06 compound treatment 277390.0 -166000.0 -0.93 443550.0 27300.0 0.16 -0.5481 -0.5787 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G07 compound treatment 340240.0 -103000.0 -0.58 488600.0 72400.0 0.42 -0.1132 -0.1581 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G08 compound treatment 253680.0 -190000.0 -1.07 480890.0 64700.0 0.38 -0.4894 -0.4326 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G09 compound treatment 484000.0 40700.0 0.23 403950.0 -12300.0 -0.07 0.1119 0.4661 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G10 compound treatment 231410.0 -212000.0 -1.19 377510.0 -38700.0 -0.22 -1.002 -0.8257 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G11 compound treatment 564500.0 121000.0 0.68 340000.0 -76200.0 -0.44 0.1701 0.2092 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G12 compound treatment 170270.0 -273000.0 -1.54 140190.0 -276000.0 -1.6 -2.2186 -0.9998 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G13 compound treatment 525630.0 82400.0 0.46 224730.0 -191000.0 -1.11 -0.4573 -0.38 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G14 compound treatment 278950.0 -164000.0 -0.92 481320.0 65100.0 0.38 -0.3871 -0.3874 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G15 compound treatment 521120.0 77900.0 0.44 369940.0 -46300.0 -0.27 0.1202 0.2339 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G16 compound treatment 392960.0 -50300.0 -0.28 300570.0 -116000.0 -0.67 -0.6744 -0.9265 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G17 compound treatment 363610.0 -79700.0 -0.45 497790.0 81600.0 0.47 0.0175 0.0268 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G18 compound treatment 550030.0 107000.0 0.6 496560.0 80400.0 0.47 0.7545 0.9921 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G19 mock treatment 416670.0 -26600.0 -0.15 426610.0 10400.0 0.06 -0.0632 -0.3915 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G20 mock treatment 583270.0 140000.0 0.79 471230.0 55000.0 0.32 0.783 0.9208 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G21 compound treatment 270570.0 -173000.0 -0.97 430350.0 14100.0 0.08 -0.6294 -0.6452 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G22 compound treatment 499860.0 56600.0 0.32 362300.0 -53900.0 -0.31 0.0042 0.0095 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G23 compound treatment 258730.0 -185000.0 -1.04 353290.0 -62900.0 -0.36 -0.9926 -0.9015 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 G24 compound treatment 364120.0 -79100.0 -0.45 358580.0 -57600.0 -0.33 -0.5514 -0.99 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H01 compound treatment 432870.0 -10400.0 -0.06 268590.0 -148000.0 -0.86 -0.6467 -0.7537 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H02 compound treatment 155840.0 -287000.0 -1.62 154840.0 -261000.0 -1.52 -2.2159 -0.9995 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H03 mock treatment 356220.0 -87000.0 -0.49 436200.0 20000.0 0.12 -0.2645 -0.5253 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H04 mock treatment 541980.0 98700.0 0.56 351260.0 -64900.0 -0.38 0.1266 0.1886 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H05 compound treatment 306630.0 -137000.0 -0.77 395630.0 -20600.0 -0.12 -0.6283 -0.8072 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H06 compound treatment 278360.0 -165000.0 -0.93 258310.0 -158000.0 -0.92 -1.3039 -1.0 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H07 compound treatment 303710.0 -140000.0 -0.79 382980.0 -33200.0 -0.19 -0.6918 -0.8552 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H08 mock treatment 516260.0 73000.0 0.41 480840.0 64600.0 0.37 0.5556 0.9989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H09 compound treatment 393880.0 -49400.0 -0.28 368720.0 -47500.0 -0.28 -0.3913 -1.0 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H10 mock treatment 522660.0 79400.0 0.45 389620.0 -26600.0 -0.15 0.207 0.4379 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H11 compound treatment 522260.0 79000.0 0.44 355270.0 -60900.0 -0.35 0.0646 0.1137 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H12 mock treatment 545090.0 102000.0 0.57 469090.0 52900.0 0.31 0.6222 0.957 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H13 compound treatment 285870.0 -157000.0 -0.89 310510.0 -106000.0 -0.61 -1.06 -0.9838 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H14 mock treatment 386400.0 -56900.0 -0.32 329950.0 -86300.0 -0.5 -0.5801 -0.9767 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H15 compound treatment 456320.0 13100.0 0.07 371530.0 -44700.0 -0.26 -0.1312 -0.4872 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H16 mock treatment 297510.0 -146000.0 -0.82 350160.0 -66000.0 -0.38 -0.851 -0.9398 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H17 compound treatment 410300.0 -33000.0 -0.19 208000.0 -208000.0 -1.21 -0.985 -0.8063 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H18 mock treatment 546310.0 103000.0 0.58 399680.0 -16500.0 -0.1 0.3424 0.5824 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H19 mock treatment 568730.0 125000.0 0.71 356960.0 -59200.0 -0.34 0.2565 0.3265 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H20 mock treatment 405300.0 -38000.0 -0.21 530210.0 114000.0 0.66 0.3164 0.4554 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H21 compound treatment 274730.0 -169000.0 -0.95 394370.0 -21800.0 -0.13 -0.7604 -0.7944 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H22 mock treatment 485440.0 42200.0 0.24 197850.0 -218000.0 -1.27 -0.7275 -0.5647 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H23 compound treatment 334730.0 -109000.0 -0.61 340480.0 -75700.0 -0.44 -0.7426 -0.9869 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 H24 mock treatment 321150.0 -122000.0 -0.69 502720.0 86500.0 0.5 -0.1313 -0.1543 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I01 compound treatment 436890.0 -6370.0 -0.04 384990.0 -31200.0 -0.18 -0.1534 -0.831 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I02 compound treatment 524600.0 81300.0 0.46 402610.0 -13600.0 -0.08 0.268 0.5768 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I03 compound treatment 37120.0 -406000.0 -2.29 44640.0 -372000.0 -2.15 -3.1404 -0.9996 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I04 compound treatment 345490.0 -97800.0 -0.55 158810.0 -257000.0 -1.49 -1.4447 -0.9081 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I05 mock treatment 300110.0 -143000.0 -0.81 487310.0 71100.0 0.41 -0.2783 -0.3074 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I06 mock treatment 567850.0 125000.0 0.7 484580.0 68400.0 0.4 0.7763 0.9635 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I07 compound treatment 439720.0 -3540.0 -0.02 471620.0 55400.0 0.32 0.2131 0.662 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I08 compound treatment 215200.0 -228000.0 -1.28 263370.0 -153000.0 -0.89 -1.5346 -0.9836 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I09 compound treatment 305070.0 -138000.0 -0.78 496480.0 80300.0 0.47 -0.2209 -0.2437 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I10 compound treatment 193280.0 -250000.0 -1.41 208070.0 -208000.0 -1.21 -1.8486 -0.9971 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I11 compound treatment 293830.0 -149000.0 -0.84 427540.0 11300.0 0.07 -0.5484 -0.6499 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I12 compound treatment 261340.0 -182000.0 -1.02 289340.0 -127000.0 -0.74 -1.2444 -0.9868 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I13 compound treatment 526270.0 83000.0 0.47 368970.0 -47200.0 -0.27 0.1367 0.2524 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I14 compound treatment 164060.0 -279000.0 -1.57 171710.0 -244000.0 -1.42 -2.114 -0.9987 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I15 compound treatment 326510.0 -117000.0 -0.66 442570.0 26400.0 0.15 -0.3566 -0.5285 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I16 compound treatment 139050.0 -304000.0 -1.71 118260.0 -298000.0 -1.73 -2.4328 -1.0 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I17 compound treatment 488410.0 45100.0 0.25 227780.0 -188000.0 -1.09 -0.593 -0.5285 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I18 compound treatment 211220.0 -232000.0 -1.31 287230.0 -129000.0 -0.75 -1.4526 -0.965 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I19 compound treatment 414490.0 -28800.0 -0.16 427310.0 11100.0 0.06 -0.069 -0.3959 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I20 compound treatment 217080.0 -226000.0 -1.27 307260.0 -109000.0 -0.63 -1.3471 -0.9477 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I21 mock treatment 336000.0 -107000.0 -0.6 405540.0 -10700.0 -0.06 -0.4707 -0.7755 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I22 mock treatment 249440.0 -194000.0 -1.09 390000.0 -26200.0 -0.15 -0.879 -0.7979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I23 compound treatment 241960.0 -201000.0 -1.13 173120.0 -243000.0 -1.41 -1.7982 -0.9941 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 I24 compound treatment 161960.0 -281000.0 -1.58 148730.0 -267000.0 -1.55 -2.2166 -0.9999 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J01 compound treatment 386120.0 -57100.0 -0.32 428530.0 12300.0 0.07 -0.1769 -0.5369 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J02 mock treatment 334280.0 -109000.0 -0.61 436890.0 20700.0 0.12 -0.349 -0.5583 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J03 compound treatment 184100.0 -259000.0 -1.46 311370.0 -105000.0 -0.61 -1.4616 -0.9247 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J04 mock treatment 318250.0 -125000.0 -0.7 455960.0 39800.0 0.23 -0.3346 -0.4518 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J05 mock treatment 335420.0 -108000.0 -0.61 517500.0 101000.0 0.59 -0.0139 -0.0164 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J06 mock treatment 454930.0 11700.0 0.07 286580.0 -130000.0 -0.75 -0.4851 -0.6429 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J07 compound treatment 289220.0 -154000.0 -0.87 303720.0 -112000.0 -0.65 -1.0745 -0.9902 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J08 mock treatment 528120.0 84900.0 0.48 420400.0 4190.0 0.02 0.355 0.7421 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J09 compound treatment 451550.0 8290.0 0.05 424810.0 8600.0 0.05 0.0683 0.9994 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J10 mock treatment 358290.0 -85000.0 -0.48 328590.0 -87600.0 -0.51 -0.6975 -0.9995 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J11 compound treatment 309440.0 -134000.0 -0.75 376580.0 -39600.0 -0.23 -0.6952 -0.8827 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J12 mock treatment 555010.0 112000.0 0.63 385530.0 -30700.0 -0.18 0.319 0.488 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J13 compound treatment 357850.0 -85400.0 -0.48 458740.0 42500.0 0.25 -0.1656 -0.3064 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J14 mock treatment 370610.0 -72700.0 -0.41 451400.0 35200.0 0.2 -0.1449 -0.317 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J15 compound treatment 209570.0 -234000.0 -1.32 323090.0 -93100.0 -0.54 -1.3121 -0.9227 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J16 mock treatment 315900.0 -127000.0 -0.72 495520.0 79300.0 0.46 -0.1817 -0.2133 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J17 compound treatment 374500.0 -68800.0 -0.39 409600.0 -6610.0 -0.04 -0.3008 -0.7733 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J18 mock treatment 392500.0 -50800.0 -0.29 474600.0 58400.0 0.34 0.0374 0.0844 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J19 compound treatment 365160.0 -78100.0 -0.44 230760.0 -185000.0 -1.08 -1.0714 -0.9221 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J20 mock treatment 406370.0 -36900.0 -0.21 355230.0 -61000.0 -0.35 -0.3969 -0.9678 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J21 mock treatment 246280.0 -197000.0 -1.11 273650.0 -143000.0 -0.83 -1.3687 -0.9895 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J22 mock treatment 463580.0 20300.0 0.11 249660.0 -167000.0 -0.97 -0.6021 -0.619 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J23 compound treatment 322590.0 -121000.0 -0.68 264190.0 -152000.0 -0.88 -1.1037 -0.9917 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 J24 mock treatment 395690.0 -47600.0 -0.27 356800.0 -59400.0 -0.34 -0.433 -0.9922 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K01 compound treatment 6010.0 -437000.0 -2.46 5600.0 -411000.0 -2.38 -3.4244 -0.9999 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K02 compound treatment 85350.0 -358000.0 -2.01 122020.0 -294000.0 -1.71 -2.6311 -0.9966 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K03 compound treatment 7310.0 -436000.0 -2.45 7970.0 -408000.0 -2.37 -3.4095 -0.9998 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K04 compound treatment 307400.0 -136000.0 -0.76 229310.0 -187000.0 -1.08 -1.3072 -0.9854 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K05 compound treatment 178210.0 -265000.0 -1.49 53480.0 -363000.0 -2.1 -2.5426 -0.9858 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K06 compound treatment 159040.0 -284000.0 -1.6 123040.0 -293000.0 -1.7 -2.3336 -0.9995 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K07 mock treatment 586310.0 143000.0 0.81 419740.0 3530.0 0.02 0.5839 0.7249 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K08 mock treatment 615850.0 173000.0 0.97 560020.0 144000.0 0.83 1.2768 0.9971 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K09 compound treatment 499680.0 56400.0 0.32 425120.0 8910.0 0.05 0.2611 0.8115 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K10 compound treatment 324920.0 -118000.0 -0.67 329310.0 -86900.0 -0.5 -0.8274 -0.9905 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K11 compound treatment 336490.0 -107000.0 -0.6 282690.0 -134000.0 -0.77 -0.9725 -0.9922 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K12 compound treatment 535400.0 92100.0 0.52 503620.0 87400.0 0.51 0.7252 0.9999 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K13 compound treatment 632530.0 189000.0 1.07 428000.0 11800.0 0.07 0.8018 0.7509 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K14 compound treatment 441150.0 -2110.0 -0.01 499010.0 82800.0 0.48 0.3312 0.6894 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K15 mock treatment 446560.0 3300.0 0.02 603530.0 187000.0 1.09 0.7813 0.7191 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K16 mock treatment 404010.0 -39300.0 -0.22 370510.0 -45700.0 -0.27 -0.3436 -0.9959 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K17 compound treatment 523720.0 80500.0 0.45 397080.0 -19100.0 -0.11 0.2418 0.5186 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K18 compound treatment 532800.0 89500.0 0.5 571910.0 156000.0 0.9 0.9949 0.9621 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K19 compound treatment 558120.0 115000.0 0.65 586830.0 171000.0 0.99 1.1569 0.9787 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K20 compound treatment 483600.0 40300.0 0.23 409080.0 -7130.0 -0.04 0.1314 0.5691 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K21 compound treatment 476660.0 33400.0 0.19 417760.0 1550.0 0.01 0.1393 0.7401 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K22 compound treatment 356030.0 -87200.0 -0.49 413030.0 -3180.0 -0.02 -0.3603 -0.7331 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K23 mock treatment 457920.0 14700.0 0.08 331780.0 -84400.0 -0.49 -0.2879 -0.5797 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 K24 mock treatment 217690.0 -226000.0 -1.27 258400.0 -158000.0 -0.92 -1.5451 -0.9871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L01 compound treatment 361040.0 -82200.0 -0.46 340360.0 -75800.0 -0.44 -0.6383 -0.9997 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L02 mock treatment 469770.0 26500.0 0.15 315060.0 -101000.0 -0.59 -0.3093 -0.5109 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L03 compound treatment 540640.0 97400.0 0.55 305960.0 -110000.0 -0.64 -0.0645 -0.0765 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L04 mock treatment 524410.0 81100.0 0.46 451490.0 35300.0 0.2 0.4677 0.9344 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L05 compound treatment 341120.0 -102000.0 -0.58 324000.0 -92200.0 -0.53 -0.7847 -0.9993 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L06 mock treatment 525210.0 81900.0 0.46 375800.0 -40400.0 -0.23 0.1605 0.3102 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L07 mock treatment 456700.0 13400.0 0.08 408960.0 -7250.0 -0.04 0.0238 0.2747 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L08 mock treatment 385440.0 -57800.0 -0.33 476240.0 60000.0 0.35 0.016 0.0336 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L09 compound treatment 577760.0 134000.0 0.76 441620.0 25400.0 0.15 0.6396 0.8292 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L10 mock treatment 495060.0 51800.0 0.29 568810.0 153000.0 0.89 0.832 0.8929 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L11 compound treatment 472320.0 29100.0 0.16 420390.0 4180.0 0.02 0.1328 0.8032 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L12 mock treatment 598050.0 155000.0 0.87 521160.0 105000.0 0.61 1.0466 0.9846 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L13 compound treatment 600240.0 157000.0 0.88 518600.0 102000.0 0.59 1.0448 0.9813 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L14 mock treatment 542460.0 99200.0 0.56 591720.0 176000.0 1.02 1.1146 0.9601 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L15 mock treatment 470190.0 26900.0 0.15 452860.0 36700.0 0.21 0.2575 0.9863 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L16 mock treatment 510470.0 67200.0 0.38 428870.0 12700.0 0.07 0.3195 0.8289 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L17 compound treatment 599930.0 157000.0 0.88 502500.0 86300.0 0.5 0.9775 0.964 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L18 mock treatment 566530.0 123000.0 0.69 391910.0 -24300.0 -0.14 0.3911 0.5523 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L19 compound treatment 466630.0 23400.0 0.13 486670.0 70500.0 0.41 0.382 0.8898 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L20 mock treatment 576000.0 133000.0 0.75 572130.0 156000.0 0.9 1.1678 0.9955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L21 compound treatment 458290.0 15000.0 0.08 493700.0 77500.0 0.45 0.3776 0.8257 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L22 mock treatment 552920.0 110000.0 0.62 289640.0 -127000.0 -0.73 -0.0825 -0.086 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L23 mock treatment 550880.0 108000.0 0.61 510570.0 94400.0 0.55 0.8154 0.9987 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 L24 mock treatment 381830.0 -61400.0 -0.35 488170.0 72000.0 0.42 0.0506 0.0933 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M01 compound treatment 7690.0 -436000.0 -2.45 8670.0 -408000.0 -2.36 -3.4051 -0.9998 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M02 compound treatment 259740.0 -184000.0 -1.03 234780.0 -181000.0 -1.05 -1.4745 -1.0 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M03 compound treatment 277360.0 -166000.0 -0.93 292600.0 -124000.0 -0.72 -1.1673 -0.9915 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M04 compound treatment 479310.0 36000.0 0.2 243380.0 -173000.0 -1.0 -0.5652 -0.5527 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M05 compound treatment 17360.0 -426000.0 -2.4 14010.0 -402000.0 -2.33 -3.3447 -0.9999 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M06 compound treatment 528090.0 84800.0 0.48 395520.0 -20700.0 -0.12 0.2528 0.5135 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M07 compound treatment 550850.0 108000.0 0.61 465980.0 49800.0 0.29 0.6324 0.9425 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M08 compound treatment 443520.0 260.0 0.0 328280.0 -87900.0 -0.51 -0.3595 -0.7051 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M09 mock treatment 467950.0 24700.0 0.14 395390.0 -20800.0 -0.12 0.0129 0.0701 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M10 mock treatment 328100.0 -115000.0 -0.65 447950.0 31700.0 0.18 -0.3282 -0.4871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M11 compound treatment 448110.0 4850.0 0.03 518480.0 102000.0 0.59 0.4387 0.7389 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M12 compound treatment 502450.0 59200.0 0.33 404660.0 -11500.0 -0.07 0.1883 0.5539 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M13 mock treatment 445440.0 2180.0 0.01 520210.0 104000.0 0.6 0.4352 0.7213 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M14 mock treatment 567470.0 124000.0 0.7 574010.0 158000.0 0.92 1.1416 0.9912 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M15 compound treatment 510780.0 67500.0 0.38 327330.0 -88900.0 -0.52 -0.0957 -0.1494 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M16 compound treatment 549990.0 107000.0 0.6 452560.0 36400.0 0.21 0.5739 0.9013 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M17 compound treatment 598080.0 155000.0 0.87 369760.0 -46400.0 -0.27 0.4258 0.4668 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M18 compound treatment 532100.0 88800.0 0.5 455620.0 39400.0 0.23 0.5153 0.937 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M19 compound treatment 320400.0 -123000.0 -0.69 381600.0 -34600.0 -0.2 -0.631 -0.8762 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M20 compound treatment 390010.0 -53300.0 -0.3 358150.0 -58100.0 -0.34 -0.4501 -0.9983 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M21 compound treatment 258200.0 -185000.0 -1.04 376770.0 -39400.0 -0.23 -0.8984 -0.8423 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M22 compound treatment 381930.0 -61300.0 -0.35 349230.0 -67000.0 -0.39 -0.5188 -0.9983 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M23 compound treatment 539970.0 96700.0 0.54 486360.0 70200.0 0.41 0.6727 0.9897 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 M24 compound treatment 253620.0 -190000.0 -1.07 245020.0 -171000.0 -0.99 -1.4569 -0.9993 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N01 compound treatment 536390.0 93100.0 0.52 372550.0 -43700.0 -0.25 0.1917 0.3292 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N02 mock treatment 436080.0 -7180.0 -0.04 599860.0 184000.0 1.07 0.7245 0.6798 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N03 compound treatment 523680.0 80400.0 0.45 401300.0 -14900.0 -0.09 0.259 0.5619 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N04 mock treatment 399610.0 -43700.0 -0.25 377710.0 -38500.0 -0.22 -0.3316 -0.9989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N05 compound treatment 520760.0 77500.0 0.44 269830.0 -146000.0 -0.85 -0.2918 -0.3057 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N06 mock treatment 414090.0 -29200.0 -0.16 488580.0 72400.0 0.42 0.1807 0.4009 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N07 compound treatment 494630.0 51400.0 0.29 533440.0 117000.0 0.68 0.6852 0.9275 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N08 mock treatment 530270.0 87000.0 0.49 503040.0 86800.0 0.5 0.7024 0.9999 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N09 mock treatment 526650.0 83400.0 0.47 487640.0 71400.0 0.41 0.6249 0.9981 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N10 mock treatment 561300.0 118000.0 0.66 396070.0 -20100.0 -0.12 0.3873 0.574 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N11 compound treatment 540480.0 97200.0 0.55 447840.0 31600.0 0.18 0.5167 0.8952 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N12 mock treatment 557990.0 115000.0 0.65 493370.0 77200.0 0.45 0.7731 0.9839 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N13 mock treatment 584480.0 141000.0 0.8 374650.0 -41600.0 -0.24 0.3917 0.4716 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N14 mock treatment 556960.0 114000.0 0.64 434460.0 18300.0 0.11 0.5275 0.813 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N15 compound treatment 468230.0 25000.0 0.14 496380.0 80200.0 0.46 0.4282 0.8815 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N16 mock treatment 513760.0 70500.0 0.4 408870.0 -7340.0 -0.04 0.2505 0.6277 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N17 compound treatment 427540.0 -15700.0 -0.09 539110.0 123000.0 0.71 0.4414 0.6146 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N18 mock treatment 525820.0 82600.0 0.46 283840.0 -132000.0 -0.77 -0.2142 -0.2387 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N19 compound treatment 326680.0 -117000.0 -0.66 325850.0 -90400.0 -0.52 -0.8346 -0.9938 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N20 mock treatment 474670.0 31400.0 0.18 412960.0 -3250.0 -0.02 0.1117 0.6282 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N21 compound treatment 395720.0 -47500.0 -0.27 263740.0 -152000.0 -0.88 -0.8145 -0.8816 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N22 mock treatment 531950.0 88700.0 0.5 437180.0 21000.0 0.12 0.439 0.8544 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N23 compound treatment 382400.0 -60900.0 -0.34 313330.0 -103000.0 -0.6 -0.6641 -0.9653 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 N24 mock treatment 308510.0 -135000.0 -0.76 259840.0 -156000.0 -0.91 -1.1776 -0.9961 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O01 compound treatment 118950.0 -324000.0 -1.83 121760.0 -294000.0 -1.71 -2.4984 -0.9994 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O02 compound treatment 366310.0 -77000.0 -0.43 527360.0 111000.0 0.64 0.1495 0.1925 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O03 compound treatment 517600.0 74300.0 0.42 457280.0 41100.0 0.24 0.4644 0.9643 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O04 compound treatment 401200.0 -42100.0 -0.24 325120.0 -91100.0 -0.53 -0.541 -0.9345 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O05 compound treatment 428390.0 -14900.0 -0.08 439320.0 23100.0 0.13 0.0356 0.2252 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O06 compound treatment 290370.0 -153000.0 -0.86 343520.0 -72700.0 -0.42 -0.9067 -0.9461 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O07 compound treatment 565210.0 122000.0 0.69 487680.0 71500.0 0.41 0.7785 0.9708 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O08 compound treatment 294800.0 -148000.0 -0.84 305870.0 -110000.0 -0.64 -1.0434 -0.9913 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O09 compound treatment 417120.0 -26100.0 -0.15 539680.0 123000.0 0.72 0.4023 0.5503 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O10 compound treatment 487420.0 44200.0 0.25 382270.0 -33900.0 -0.2 0.0366 0.1155 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O11 mock treatment 424420.0 -18800.0 -0.11 449480.0 33300.0 0.19 0.0614 0.2791 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O12 mock treatment 388960.0 -54300.0 -0.31 559570.0 143000.0 0.83 0.3718 0.4197 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O13 compound treatment 528280.0 85000.0 0.48 464510.0 48300.0 0.28 0.5365 0.9674 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O14 compound treatment 544710.0 101000.0 0.57 451090.0 34900.0 0.2 0.5469 0.9026 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O15 compound treatment 424670.0 -18600.0 -0.1 402010.0 -14200.0 -0.08 -0.1322 -0.993 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O16 compound treatment 343250.0 -100000.0 -0.56 563950.0 148000.0 0.86 0.2078 0.2026 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O17 compound treatment 506270.0 63000.0 0.35 455260.0 39100.0 0.23 0.411 0.9765 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O18 compound treatment 526890.0 83600.0 0.47 453120.0 36900.0 0.21 0.4843 0.9364 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O19 compound treatment 528320.0 85100.0 0.48 421240.0 5030.0 0.03 0.3592 0.7488 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O20 compound treatment 337330.0 -106000.0 -0.6 251780.0 -164000.0 -0.95 -1.096 -0.9744 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O21 compound treatment 370590.0 -72700.0 -0.41 546190.0 130000.0 0.75 0.2438 0.2842 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O22 compound treatment 374000.0 -69300.0 -0.39 337680.0 -78500.0 -0.46 -0.5977 -0.997 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O23 compound treatment 355680.0 -87600.0 -0.49 436840.0 20600.0 0.12 -0.264 -0.5204 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 O24 compound treatment 492580.0 49300.0 0.28 346880.0 -69300.0 -0.4 -0.088 -0.18 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P01 compound treatment 208060.0 -235000.0 -1.32 270690.0 -146000.0 -0.84 -1.533 -0.9763 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P02 mock treatment 441720.0 -1540.0 -0.01 320000.0 -96200.0 -0.56 -0.4007 -0.718 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P03 compound treatment 269890.0 -173000.0 -0.98 310020.0 -106000.0 -0.62 -1.1256 -0.9753 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P04 mock treatment 353790.0 -89500.0 -0.5 434130.0 17900.0 0.1 -0.2827 -0.5496 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P05 compound treatment 321240.0 -122000.0 -0.69 405990.0 -10200.0 -0.06 -0.5276 -0.7653 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P06 mock treatment 450830.0 7570.0 0.04 392880.0 -23300.0 -0.14 -0.0655 -0.462 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P07 compound treatment 348220.0 -95000.0 -0.54 420160.0 3950.0 0.02 -0.3621 -0.6762 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P08 mock treatment 331870.0 -111000.0 -0.63 328360.0 -87800.0 -0.51 -0.8037 -0.9947 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P09 compound treatment 327840.0 -115000.0 -0.65 373830.0 -42400.0 -0.25 -0.6332 -0.9115 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P10 mock treatment 355460.0 -87800.0 -0.49 425500.0 9290.0 0.05 -0.3114 -0.6263 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P11 mock treatment 336530.0 -107000.0 -0.6 483530.0 67300.0 0.39 -0.1488 -0.2076 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P12 mock treatment 368320.0 -74900.0 -0.42 314310.0 -102000.0 -0.59 -0.7162 -0.9864 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P13 compound treatment 282790.0 -160000.0 -0.9 298240.0 -118000.0 -0.68 -1.1225 -0.9906 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P14 mock treatment 358240.0 -85000.0 -0.48 442980.0 26800.0 0.16 -0.2286 -0.4544 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P15 compound treatment 354090.0 -89200.0 -0.5 203620.0 -213000.0 -1.23 -1.2267 -0.9216 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P16 mock treatment 419700.0 -23600.0 -0.13 408830.0 -7380.0 -0.04 -0.124 -0.89 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P17 compound treatment 297860.0 -145000.0 -0.82 275690.0 -141000.0 -0.81 -1.155 -1.0 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P18 mock treatment 304700.0 -139000.0 -0.78 236560.0 -180000.0 -1.04 -1.2883 -0.9898 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P19 compound treatment 464450.0 21200.0 0.12 295260.0 -121000.0 -0.7 -0.4116 -0.5785 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P20 mock treatment 377990.0 -65300.0 -0.37 315160.0 -101000.0 -0.59 -0.6742 -0.9747 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P21 compound treatment 368380.0 -74900.0 -0.42 259150.0 -157000.0 -0.91 -0.9421 -0.9387 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P22 mock treatment 312530.0 -131000.0 -0.74 299520.0 -117000.0 -0.68 -0.9989 -0.9991 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P23 compound treatment 242910.0 -200000.0 -1.13 236080.0 -180000.0 -1.04 -1.5362 -0.9993 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2283 P24 mock treatment 208400.0 -235000.0 -1.32 286890.0 -129000.0 -0.75 -1.4652 -0.9639 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A01 mock treatment 443280.0 709.0 0.0 298780.0 -118000.0 -0.68 -0.4804 -0.703 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A02 compound treatment 516280.0 73700.0 0.41 202180.0 -214000.0 -1.24 -0.5859 -0.4469 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A03 mock treatment 139840.0 -303000.0 -1.7 227850.0 -189000.0 -1.09 -1.9791 -0.9771 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A04 compound treatment 447520.0 4950.0 0.03 205500.0 -211000.0 -1.22 -0.846 -0.6908 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A05 compound treatment 208340.0 -234000.0 -1.32 270980.0 -146000.0 -0.84 -1.5296 -0.9768 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A06 compound treatment 292710.0 -150000.0 -0.84 346990.0 -69600.0 -0.4 -0.882 -0.9431 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A07 mock treatment 401200.0 -41400.0 -0.23 298190.0 -118000.0 -0.69 -0.6503 -0.8967 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A08 compound treatment 233290.0 -209000.0 -1.18 305210.0 -111000.0 -0.65 -1.2899 -0.96 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A09 compound treatment 515960.0 73400.0 0.41 371280.0 -45300.0 -0.26 0.1062 0.217 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A10 compound treatment 536640.0 94100.0 0.53 369050.0 -47600.0 -0.28 0.1794 0.3005 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A11 mock treatment 377020.0 -65600.0 -0.37 271080.0 -146000.0 -0.84 -0.8577 -0.9312 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A12 compound treatment 473640.0 31100.0 0.17 274180.0 -142000.0 -0.83 -0.4604 -0.5453 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A13 mock treatment 438610.0 -3960.0 -0.02 292650.0 -124000.0 -0.72 -0.5241 -0.7287 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A14 mock treatment 219410.0 -223000.0 -1.26 521650.0 105000.0 0.61 -0.4576 -0.3277 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A15 compound treatment 441630.0 -941.0 -0.01 388030.0 -28600.0 -0.17 -0.1209 -0.7293 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A16 compound treatment 390740.0 -51800.0 -0.29 404640.0 -12000.0 -0.07 -0.2554 -0.8516 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A17 compound treatment 148170.0 -294000.0 -1.66 246000.0 -171000.0 -0.99 -1.8716 -0.9696 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A18 compound treatment 15840.0 -427000.0 -2.4 14520.0 -402000.0 -2.33 -3.3476 -0.9999 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A19 compound treatment 461140.0 18600.0 0.1 318420.0 -98200.0 -0.57 -0.3287 -0.5678 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A20 compound treatment 342090.0 -100000.0 -0.57 421070.0 4460.0 0.03 -0.3817 -0.6741 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A21 compound treatment 496890.0 54300.0 0.31 403610.0 -13000.0 -0.08 0.1629 0.5173 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A22 compound treatment 560180.0 118000.0 0.66 483720.0 67100.0 0.39 0.7434 0.9679 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A23 compound treatment 523560.0 81000.0 0.46 519120.0 103000.0 0.59 0.7428 0.9914 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 A24 compound treatment 244870.0 -198000.0 -1.11 181630.0 -235000.0 -1.36 -1.7506 -0.9949 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B01 compound treatment 516350.0 73800.0 0.42 537630.0 121000.0 0.7 0.79 0.9687 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B02 compound treatment 223280.0 -219000.0 -1.23 238340.0 -178000.0 -1.03 -1.604 -0.9961 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B03 compound treatment 534290.0 91700.0 0.52 570250.0 154000.0 0.89 0.9952 0.9663 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B04 compound treatment 377840.0 -64700.0 -0.36 495440.0 78800.0 0.46 0.0656 0.1122 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B05 compound treatment 521020.0 78400.0 0.44 280750.0 -136000.0 -0.79 -0.2449 -0.2711 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B06 compound treatment 380240.0 -62300.0 -0.35 297950.0 -119000.0 -0.69 -0.7347 -0.9511 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B07 compound treatment 467270.0 24700.0 0.14 469730.0 53100.0 0.31 0.3162 0.9354 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B08 compound treatment 427060.0 -15500.0 -0.09 263080.0 -154000.0 -0.89 -0.6913 -0.7727 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B09 compound treatment 424000.0 -18600.0 -0.1 297290.0 -119000.0 -0.69 -0.5632 -0.8048 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B10 compound treatment 449650.0 7080.0 0.04 483330.0 66700.0 0.39 0.3018 0.7758 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B11 compound treatment 481500.0 38900.0 0.22 535120.0 119000.0 0.69 0.641 0.8885 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B12 compound treatment 301320.0 -141000.0 -0.8 536000.0 119000.0 0.69 -0.0727 -0.0689 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B13 mock treatment 558720.0 116000.0 0.65 495430.0 78800.0 0.46 0.7856 0.9847 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B14 mock treatment 551650.0 109000.0 0.61 488390.0 71800.0 0.42 0.7286 0.9821 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B15 compound treatment 259770.0 -183000.0 -1.03 286880.0 -130000.0 -0.75 -1.2597 -0.9881 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B16 compound treatment 317920.0 -125000.0 -0.7 304570.0 -112000.0 -0.65 -0.9556 -0.9993 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B17 compound treatment 325570.0 -117000.0 -0.66 193570.0 -223000.0 -1.29 -1.3804 -0.951 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B18 compound treatment 345140.0 -97400.0 -0.55 321290.0 -95300.0 -0.55 -0.7787 -1.0 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B19 compound treatment 386480.0 -56100.0 -0.32 597370.0 181000.0 1.05 0.518 0.4731 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B20 mock treatment 486080.0 43500.0 0.24 549760.0 133000.0 0.77 0.7192 0.8878 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B21 compound treatment 431150.0 -11400.0 -0.06 328080.0 -88500.0 -0.51 -0.4085 -0.7895 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B22 compound treatment 356050.0 -86500.0 -0.49 371250.0 -45400.0 -0.26 -0.5304 -0.9582 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B23 compound treatment 484090.0 41500.0 0.23 328480.0 -88100.0 -0.51 -0.1961 -0.349 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 B24 compound treatment 470690.0 28100.0 0.16 296610.0 -120000.0 -0.7 -0.3802 -0.5327 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C01 compound treatment 431560.0 -11000.0 -0.06 411130.0 -5480.0 -0.03 -0.0663 -0.9518 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C02 compound treatment 366720.0 -75900.0 -0.43 316540.0 -100000.0 -0.58 -0.7123 -0.9886 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C03 compound treatment 216340.0 -226000.0 -1.27 288830.0 -128000.0 -0.74 -1.4246 -0.9668 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C04 compound treatment 327640.0 -115000.0 -0.65 206050.0 -211000.0 -1.22 -1.321 -0.9559 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C05 compound treatment 296090.0 -146000.0 -0.82 215000.0 -202000.0 -1.17 -1.4099 -0.9854 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C06 compound treatment 343790.0 -98800.0 -0.56 334340.0 -82300.0 -0.48 -0.7306 -0.9971 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C07 compound treatment 272410.0 -170000.0 -0.96 257660.0 -159000.0 -0.92 -1.3292 -0.9998 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C08 compound treatment 266880.0 -176000.0 -0.99 218150.0 -198000.0 -1.15 -1.5132 -0.9972 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C09 compound treatment 429760.0 -12800.0 -0.07 300130.0 -116000.0 -0.68 -0.5287 -0.7782 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C10 compound treatment 493470.0 50900.0 0.29 337360.0 -79300.0 -0.46 -0.1224 -0.226 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C11 mock treatment 503200.0 60600.0 0.34 448250.0 31600.0 0.18 0.3711 0.9576 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C12 mock treatment 545830.0 103000.0 0.58 400500.0 -16100.0 -0.09 0.345 0.5859 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C13 compound treatment 289770.0 -153000.0 -0.86 458400.0 41800.0 0.24 -0.4369 -0.4888 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C14 compound treatment 457240.0 14700.0 0.08 297340.0 -119000.0 -0.69 -0.4307 -0.6183 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C15 mock treatment 479700.0 37100.0 0.21 498910.0 82300.0 0.48 0.4853 0.9314 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C16 mock treatment 350790.0 -91800.0 -0.52 326720.0 -89900.0 -0.52 -0.734 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C17 compound treatment 326440.0 -116000.0 -0.65 272160.0 -144000.0 -0.84 -1.0546 -0.9925 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C18 compound treatment 358770.0 -83800.0 -0.47 321760.0 -94900.0 -0.55 -0.7225 -0.9971 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C19 compound treatment 485760.0 43200.0 0.24 495270.0 78700.0 0.46 0.4945 0.9566 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C20 compound treatment 241250.0 -201000.0 -1.13 153160.0 -263000.0 -1.53 -1.8818 -0.9892 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C21 compound treatment 98240.0 -344000.0 -1.94 62740.0 -354000.0 -2.05 -2.8218 -0.9996 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C22 compound treatment 396710.0 -45900.0 -0.26 311120.0 -105000.0 -0.61 -0.6152 -0.9264 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C23 compound treatment 564090.0 122000.0 0.68 228590.0 -188000.0 -1.09 -0.2873 -0.2232 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 C24 compound treatment 218050.0 -225000.0 -1.26 283870.0 -133000.0 -0.77 -1.4381 -0.9717 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D01 compound treatment 284190.0 -158000.0 -0.89 524110.0 108000.0 0.62 -0.1896 -0.1743 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D02 compound treatment 403400.0 -39200.0 -0.22 476810.0 60200.0 0.35 0.0909 0.2202 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D03 compound treatment 371100.0 -71500.0 -0.4 346160.0 -70500.0 -0.41 -0.5734 -1.0 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D04 mock treatment 481610.0 39000.0 0.22 321700.0 -94900.0 -0.55 -0.2338 -0.3945 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D05 compound treatment 421980.0 -20600.0 -0.12 510730.0 94100.0 0.55 0.304 0.5448 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D06 compound treatment 410490.0 -32100.0 -0.18 345050.0 -71600.0 -0.42 -0.4212 -0.9305 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D07 compound treatment 386240.0 -56300.0 -0.32 416610.0 0.0 0.0 -0.2242 -0.7071 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D08 mock treatment 517300.0 74700.0 0.42 606560.0 190000.0 1.1 1.0764 0.9128 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D09 compound treatment 542400.0 99800.0 0.56 402880.0 -13700.0 -0.08 0.3411 0.6009 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D10 compound treatment 308130.0 -134000.0 -0.76 222920.0 -194000.0 -1.12 -1.3295 -0.9815 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D11 mock treatment 656640.0 214000.0 1.21 500670.0 84100.0 0.49 1.1969 0.9207 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D12 mock treatment 521710.0 79100.0 0.45 531650.0 115000.0 0.67 0.7868 0.9807 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D13 mock treatment 532030.0 89500.0 0.5 384000.0 -32600.0 -0.19 0.2224 0.4134 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D14 compound treatment 231150.0 -211000.0 -1.19 510210.0 93600.0 0.54 -0.4578 -0.3499 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D15 mock treatment 434420.0 -8150.0 -0.05 245760.0 -171000.0 -0.99 -0.7331 -0.7391 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D16 mock treatment 586910.0 144000.0 0.81 364480.0 -52100.0 -0.3 0.3608 0.4161 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D17 compound treatment 341090.0 -101000.0 -0.57 348080.0 -68500.0 -0.4 -0.685 -0.9843 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D18 compound treatment 461060.0 18500.0 0.1 471630.0 55000.0 0.32 0.2992 0.8915 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D19 compound treatment 14240.0 -428000.0 -2.41 12660.0 -404000.0 -2.34 -3.3616 -0.9999 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D20 compound treatment 487450.0 44900.0 0.25 512160.0 95600.0 0.55 0.5705 0.9367 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D21 compound treatment 483570.0 41000.0 0.23 290420.0 -126000.0 -0.73 -0.3543 -0.4617 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D22 compound treatment 339200.0 -103000.0 -0.58 451410.0 34800.0 0.2 -0.2688 -0.4364 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D23 mock treatment 531680.0 89100.0 0.5 455390.0 38800.0 0.22 0.5137 0.9345 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 D24 compound treatment 453300.0 10700.0 0.06 174340.0 -242000.0 -1.41 -0.9508 -0.6761 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E01 mock treatment 358500.0 -84100.0 -0.47 456960.0 40400.0 0.23 -0.1692 -0.3205 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E02 mock treatment 367600.0 -75000.0 -0.42 364290.0 -52300.0 -0.3 -0.513 -0.9869 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E03 mock treatment 322100.0 -120000.0 -0.68 338130.0 -78500.0 -0.46 -0.8014 -0.9812 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E04 compound treatment 334780.0 -108000.0 -0.61 240860.0 -176000.0 -1.02 -1.1498 -0.9693 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E05 compound treatment 282240.0 -160000.0 -0.9 337160.0 -79500.0 -0.46 -0.964 -0.9513 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E06 compound treatment 272860.0 -170000.0 -0.96 300800.0 -116000.0 -0.67 -1.1505 -0.9851 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E07 compound treatment 340280.0 -102000.0 -0.58 303360.0 -113000.0 -0.66 -0.8716 -0.9979 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E08 compound treatment 344550.0 -98000.0 -0.55 353920.0 -62700.0 -0.36 -0.6473 -0.9795 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E09 mock treatment 587730.0 145000.0 0.82 593620.0 177000.0 1.03 1.3037 0.9936 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E10 mock treatment 589710.0 147000.0 0.83 470970.0 54400.0 0.32 0.8086 0.9124 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E11 compound treatment 199040.0 -244000.0 -1.37 169130.0 -247000.0 -1.44 -1.9843 -0.9997 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E12 compound treatment 524640.0 82100.0 0.46 402980.0 -13600.0 -0.08 0.2708 0.5777 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E13 compound treatment 486180.0 43600.0 0.25 367220.0 -49400.0 -0.29 -0.0289 -0.0767 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E14 compound treatment 418910.0 -23700.0 -0.13 346930.0 -69700.0 -0.4 -0.3799 -0.8929 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E15 compound treatment 147260.0 -295000.0 -1.66 126270.0 -290000.0 -1.68 -2.3662 -1.0 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E16 compound treatment 317300.0 -125000.0 -0.71 138400.0 -278000.0 -1.61 -1.6395 -0.9311 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E17 mock treatment 326560.0 -116000.0 -0.65 427650.0 11000.0 0.06 -0.4165 -0.6347 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E18 mock treatment 531520.0 88900.0 0.5 270580.0 -146000.0 -0.85 -0.2448 -0.2488 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E19 compound treatment 467430.0 24900.0 0.14 385210.0 -31400.0 -0.18 -0.0298 -0.1298 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E20 compound treatment 349370.0 -93200.0 -0.52 360640.0 -56000.0 -0.32 -0.6005 -0.9734 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E21 mock treatment 537980.0 95400.0 0.54 587140.0 171000.0 0.99 1.0791 0.9589 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E22 compound treatment 525280.0 82700.0 0.47 391040.0 -25600.0 -0.15 0.2244 0.4592 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E23 compound treatment 354240.0 -88300.0 -0.5 254880.0 -162000.0 -0.94 -1.0148 -0.956 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 E24 mock treatment 291200.0 -151000.0 -0.85 363620.0 -53000.0 -0.31 -0.8199 -0.9051 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F01 mock treatment 484590.0 42000.0 0.24 480420.0 63800.0 0.37 0.4289 0.9766 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F02 mock treatment 496160.0 53600.0 0.3 192180.0 -224000.0 -1.3 -0.707 -0.5292 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F03 compound treatment 254130.0 -188000.0 -1.06 334830.0 -81800.0 -0.47 -1.0855 -0.9341 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F04 compound treatment 177000.0 -266000.0 -1.5 298690.0 -118000.0 -0.68 -1.5407 -0.9372 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F05 compound treatment 198010.0 -245000.0 -1.38 207400.0 -209000.0 -1.21 -1.8314 -0.998 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F06 mock treatment 268510.0 -174000.0 -0.98 199680.0 -217000.0 -1.26 -1.5825 -0.9924 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F07 compound treatment 309600.0 -133000.0 -0.75 463120.0 46500.0 0.27 -0.3386 -0.4255 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F08 compound treatment 541070.0 98500.0 0.55 271690.0 -145000.0 -0.84 -0.2022 -0.2008 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F09 mock treatment 494130.0 51600.0 0.29 554790.0 138000.0 0.8 0.7719 0.9056 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F10 mock treatment 413160.0 -29400.0 -0.17 398990.0 -17600.0 -0.1 -0.1893 -0.9731 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F11 mock treatment 555930.0 113000.0 0.64 560070.0 143000.0 0.83 1.0395 0.9914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F12 compound treatment 248720.0 -194000.0 -1.09 286770.0 -130000.0 -0.75 -1.3041 -0.9836 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F13 compound treatment 545120.0 103000.0 0.58 245280.0 -171000.0 -0.99 -0.2944 -0.2562 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F14 compound treatment 18990.0 -424000.0 -2.38 12840.0 -404000.0 -2.34 -3.3419 -1.0 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F15 compound treatment 205950.0 -237000.0 -1.33 178150.0 -238000.0 -1.38 -1.9198 -0.9998 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F16 compound treatment 347160.0 -95400.0 -0.54 209120.0 -207000.0 -1.2 -1.2307 -0.9339 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F17 mock treatment 268690.0 -174000.0 -0.98 559050.0 142000.0 0.83 -0.108 -0.0844 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F18 mock treatment 341190.0 -101000.0 -0.57 469280.0 52700.0 0.31 -0.1876 -0.2898 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F19 compound treatment 525150.0 82600.0 0.46 321280.0 -95300.0 -0.55 -0.0622 -0.0861 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F20 compound treatment 429790.0 -12800.0 -0.07 407090.0 -9520.0 -0.06 -0.0899 -0.9914 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F21 compound treatment 399560.0 -43000.0 -0.24 389920.0 -26700.0 -0.15 -0.2807 -0.9766 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F22 compound treatment 261710.0 -181000.0 -1.02 302130.0 -114000.0 -0.66 -1.1894 -0.9785 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F23 compound treatment 397820.0 -44800.0 -0.25 309520.0 -107000.0 -0.62 -0.6173 -0.921 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 F24 compound treatment 287520.0 -155000.0 -0.87 417710.0 1100.0 0.01 -0.6127 -0.7019 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G01 compound treatment 438560.0 -4010.0 -0.02 281840.0 -135000.0 -0.78 -0.5686 -0.7272 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G02 mock treatment 586910.0 144000.0 0.81 311110.0 -106000.0 -0.61 0.1419 0.1395 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G03 mock treatment 508320.0 65700.0 0.37 472640.0 56000.0 0.32 0.4915 0.9979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G04 mock treatment 327720.0 -115000.0 -0.65 311560.0 -105000.0 -0.61 -0.888 -0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G05 compound treatment 224130.0 -218000.0 -1.23 418560.0 1950.0 0.01 -0.8615 -0.7006 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G06 compound treatment 386760.0 -55800.0 -0.31 460260.0 43700.0 0.25 -0.0432 -0.107 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G07 compound treatment 561040.0 118000.0 0.67 326030.0 -90600.0 -0.53 0.1001 0.1179 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G08 mock treatment 587840.0 145000.0 0.82 559870.0 143000.0 0.83 1.1657 1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G09 compound treatment 354030.0 -88500.0 -0.5 518240.0 102000.0 0.59 0.0643 0.0833 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G10 compound treatment 279840.0 -163000.0 -0.92 305090.0 -112000.0 -0.65 -1.1051 -0.9855 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G11 mock treatment 515610.0 73000.0 0.41 445790.0 29200.0 0.17 0.4104 0.923 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G12 compound treatment 254570.0 -188000.0 -1.06 231050.0 -186000.0 -1.08 -1.5093 -1.0 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G13 compound treatment 289840.0 -153000.0 -0.86 241230.0 -175000.0 -1.02 -1.3272 -0.9965 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G14 compound treatment 160070.0 -283000.0 -1.59 184040.0 -233000.0 -1.35 -2.0783 -0.9966 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G15 compound treatment 135420.0 -307000.0 -1.73 125930.0 -291000.0 -1.69 -2.4147 -0.9999 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G16 compound treatment 319100.0 -123000.0 -0.7 318630.0 -98000.0 -0.57 -0.8933 -0.995 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G17 mock treatment 436810.0 -5760.0 -0.03 482330.0 65700.0 0.38 0.2466 0.6446 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G18 compound treatment 80890.0 -362000.0 -2.04 79070.0 -338000.0 -1.96 -2.8239 -0.9998 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G19 mock treatment 402270.0 -40300.0 -0.23 439890.0 23300.0 0.14 -0.065 -0.246 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G20 mock treatment 362800.0 -79800.0 -0.45 285570.0 -131000.0 -0.76 -0.8549 -0.9685 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G21 compound treatment 470720.0 28100.0 0.16 212860.0 -204000.0 -1.18 -0.7235 -0.6068 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G22 compound treatment 270570.0 -172000.0 -0.97 282880.0 -134000.0 -0.78 -1.2331 -0.9939 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G23 compound treatment 381930.0 -60600.0 -0.34 365010.0 -51600.0 -0.3 -0.453 -0.9978 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 G24 compound treatment 464490.0 21900.0 0.12 200290.0 -216000.0 -1.25 -0.7998 -0.6345 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H01 compound treatment 276640.0 -166000.0 -0.93 400350.0 -16300.0 -0.09 -0.7272 -0.7746 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H02 compound treatment 189290.0 -253000.0 -1.43 233490.0 -183000.0 -1.06 -1.7592 -0.9895 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H03 mock treatment 262530.0 -180000.0 -1.01 277190.0 -139000.0 -0.81 -1.2884 -0.9937 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H04 mock treatment 420350.0 -22200.0 -0.13 236820.0 -180000.0 -1.04 -0.8257 -0.7863 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H05 compound treatment 280500.0 -162000.0 -0.91 425440.0 8830.0 0.05 -0.6089 -0.6664 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H06 compound treatment 328160.0 -114000.0 -0.64 237950.0 -179000.0 -1.04 -1.1881 -0.9738 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H07 compound treatment 270980.0 -172000.0 -0.97 193930.0 -223000.0 -1.29 -1.5962 -0.9898 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H08 compound treatment 437390.0 -5180.0 -0.03 410560.0 -6050.0 -0.04 -0.0454 -0.9958 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H09 compound treatment 325250.0 -117000.0 -0.66 320040.0 -96600.0 -0.56 -0.863 -0.9966 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H10 compound treatment 446820.0 4250.0 0.02 397970.0 -18600.0 -0.11 -0.0595 -0.5376 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H11 compound treatment 347880.0 -94700.0 -0.53 284230.0 -132000.0 -0.77 -0.9198 -0.9841 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H12 compound treatment 408500.0 -34100.0 -0.19 321760.0 -94900.0 -0.55 -0.5246 -0.9005 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H13 mock treatment 254080.0 -188000.0 -1.06 592130.0 176000.0 1.02 -0.0305 -0.0208 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H14 compound treatment 5840.0 -437000.0 -2.46 11120.0 -405000.0 -2.35 -3.4013 -0.9998 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H15 compound treatment 221890.0 -221000.0 -1.24 350880.0 -65700.0 -0.38 -1.148 -0.8834 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H16 compound treatment 475950.0 33400.0 0.19 517860.0 101000.0 0.59 0.5481 0.889 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H17 compound treatment 533080.0 90500.0 0.51 264220.0 -152000.0 -0.88 -0.2646 -0.2594 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H18 compound treatment 279310.0 -163000.0 -0.92 308160.0 -108000.0 -0.63 -1.0946 -0.9829 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H19 mock treatment 367320.0 -75300.0 -0.42 474830.0 58200.0 0.34 -0.0608 -0.1122 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H20 mock treatment 379210.0 -63400.0 -0.36 418610.0 2000.0 0.01 -0.244 -0.6838 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H21 compound treatment 15320.0 -427000.0 -2.41 11200.0 -405000.0 -2.35 -3.3633 -0.9999 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H22 compound treatment 262740.0 -180000.0 -1.01 299600.0 -117000.0 -0.68 -1.1957 -0.9811 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H23 mock treatment 338520.0 -104000.0 -0.59 399650.0 -17000.0 -0.1 -0.4837 -0.8144 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 H24 compound treatment 236260.0 -206000.0 -1.16 286050.0 -131000.0 -0.76 -1.3567 -0.9785 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I01 compound treatment 546940.0 104000.0 0.59 517080.0 100000.0 0.58 0.8275 1.0 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I02 compound treatment 287320.0 -155000.0 -0.87 355310.0 -61300.0 -0.36 -0.8694 -0.9214 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I03 compound treatment 358760.0 -83800.0 -0.47 261310.0 -155000.0 -0.9 -0.9705 -0.9545 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I04 mock treatment 416510.0 -26100.0 -0.15 498370.0 81800.0 0.47 0.2315 0.4665 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I05 mock treatment 262560.0 -180000.0 -1.01 305330.0 -111000.0 -0.65 -1.1729 -0.9763 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I06 mock treatment 317080.0 -125000.0 -0.71 326010.0 -90600.0 -0.53 -0.8711 -0.9894 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I07 compound treatment 294450.0 -148000.0 -0.83 226680.0 -190000.0 -1.1 -1.3685 -0.9906 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I08 compound treatment 250880.0 -192000.0 -1.08 323580.0 -93000.0 -0.54 -1.1446 -0.9487 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I09 compound treatment 376380.0 -66200.0 -0.37 312260.0 -104000.0 -0.61 -0.6914 -0.9729 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I10 compound treatment 488990.0 46400.0 0.26 285940.0 -131000.0 -0.76 -0.3511 -0.438 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I11 compound treatment 540040.0 97500.0 0.55 265290.0 -151000.0 -0.88 -0.2325 -0.2247 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I12 compound treatment 423330.0 -19200.0 -0.11 413600.0 -3010.0 -0.02 -0.0889 -0.8106 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I13 compound treatment 55920.0 -387000.0 -2.18 63790.0 -353000.0 -2.05 -2.986 -0.9995 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I14 compound treatment 74320.0 -368000.0 -2.07 63650.0 -353000.0 -2.05 -2.9133 -1.0 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I15 compound treatment 507410.0 64800.0 0.37 407550.0 -9060.0 -0.05 0.2209 0.5991 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I16 compound treatment 322780.0 -120000.0 -0.67 200650.0 -216000.0 -1.25 -1.3625 -0.9578 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I17 compound treatment 522750.0 80200.0 0.45 465830.0 49200.0 0.29 0.521 0.9756 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I18 compound treatment 318530.0 -124000.0 -0.7 264870.0 -152000.0 -0.88 -1.116 -0.9934 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I19 compound treatment 328120.0 -114000.0 -0.64 252250.0 -164000.0 -0.95 -1.1296 -0.9818 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I20 compound treatment 244480.0 -198000.0 -1.12 357920.0 -58700.0 -0.34 -1.0292 -0.8827 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I21 mock treatment 268880.0 -174000.0 -0.98 246440.0 -170000.0 -0.99 -1.3892 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I22 mock treatment 549140.0 107000.0 0.6 340000.0 -76600.0 -0.44 0.1101 0.1474 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I23 compound treatment 212280.0 -230000.0 -1.3 164530.0 -252000.0 -1.46 -1.9504 -0.9982 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 I24 compound treatment 210400.0 -232000.0 -1.31 139520.0 -277000.0 -1.61 -2.0605 -0.9947 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J01 compound treatment 243040.0 -200000.0 -1.12 282140.0 -134000.0 -0.78 -1.3457 -0.9841 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J02 compound treatment 290000.0 -153000.0 -0.86 363050.0 -53600.0 -0.31 -0.827 -0.9054 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J03 compound treatment 385770.0 -56800.0 -0.32 529820.0 113000.0 0.66 0.2381 0.3261 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J04 mock treatment 501960.0 59400.0 0.33 556040.0 139000.0 0.81 0.8082 0.9236 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J05 mock treatment 328970.0 -114000.0 -0.64 387390.0 -29200.0 -0.17 -0.572 -0.8646 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J06 mock treatment 449210.0 6640.0 0.04 277860.0 -139000.0 -0.8 -0.5426 -0.6735 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J07 compound treatment 368730.0 -73800.0 -0.42 271480.0 -145000.0 -0.84 -0.8891 -0.9471 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J08 compound treatment 338970.0 -104000.0 -0.58 232480.0 -184000.0 -1.07 -1.1675 -0.9595 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J09 compound treatment 321800.0 -121000.0 -0.68 470270.0 53700.0 0.31 -0.2607 -0.3487 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J10 compound treatment 310890.0 -132000.0 -0.74 277230.0 -139000.0 -0.81 -1.0958 -0.9991 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J11 compound treatment 276030.0 -167000.0 -0.94 268910.0 -148000.0 -0.86 -1.2686 -0.999 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J12 compound treatment 362080.0 -80500.0 -0.45 371430.0 -45200.0 -0.26 -0.5057 -0.9661 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J13 compound treatment 7220.0 -435000.0 -2.45 6560.0 -410000.0 -2.38 -3.4145 -0.9999 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J14 compound treatment 21680.0 -421000.0 -2.37 23380.0 -393000.0 -2.28 -3.288 -0.9998 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J15 compound treatment 224800.0 -218000.0 -1.23 295680.0 -121000.0 -0.7 -1.3628 -0.9649 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J16 mock treatment 413800.0 -28800.0 -0.16 547040.0 130000.0 0.76 0.4203 0.5434 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J17 compound treatment 25680.0 -417000.0 -2.35 24220.0 -392000.0 -2.28 -3.2686 -0.9999 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J18 mock treatment 323140.0 -119000.0 -0.67 301600.0 -115000.0 -0.67 -0.9471 -1.0 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J19 compound treatment 324070.0 -119000.0 -0.67 289440.0 -127000.0 -0.74 -0.9932 -0.9987 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J20 compound treatment 364210.0 -78400.0 -0.44 369390.0 -47200.0 -0.27 -0.5056 -0.9737 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J21 mock treatment 542720.0 100000.0 0.56 257610.0 -159000.0 -0.92 -0.2534 -0.2344 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J22 mock treatment 257960.0 -185000.0 -1.04 259280.0 -157000.0 -0.91 -1.3801 -0.9979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J23 compound treatment 294850.0 -148000.0 -0.83 253550.0 -163000.0 -0.95 -1.2567 -0.9979 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 J24 compound treatment 260820.0 -182000.0 -1.02 366140.0 -50500.0 -0.29 -0.9305 -0.8743 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K01 compound treatment 309520.0 -133000.0 -0.75 322690.0 -93900.0 -0.54 -0.9148 -0.9878 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K02 compound treatment 322150.0 -120000.0 -0.68 175720.0 -241000.0 -1.4 -1.4672 -0.9449 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K03 compound treatment 312670.0 -130000.0 -0.73 516350.0 99700.0 0.58 -0.1081 -0.1159 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K04 mock treatment 587750.0 145000.0 0.82 566130.0 150000.0 0.87 1.1911 0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K05 compound treatment 341280.0 -101000.0 -0.57 434240.0 17600.0 0.1 -0.3309 -0.5712 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K06 compound treatment 560110.0 118000.0 0.66 550340.0 134000.0 0.78 1.0163 0.9969 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K07 mock treatment 517080.0 74500.0 0.42 394680.0 -21900.0 -0.13 0.2067 0.4715 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K08 mock treatment 413390.0 -29200.0 -0.16 425940.0 9330.0 0.05 -0.0779 -0.4504 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K09 compound treatment 337210.0 -105000.0 -0.59 365890.0 -50700.0 -0.29 -0.6274 -0.9476 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K10 compound treatment 404530.0 -38000.0 -0.21 408600.0 -8010.0 -0.05 -0.1843 -0.8409 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K11 compound treatment 385120.0 -57500.0 -0.32 424190.0 7580.0 0.04 -0.1976 -0.6054 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K12 compound treatment 398910.0 -43700.0 -0.25 198780.0 -218000.0 -1.26 -1.0671 -0.8291 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K13 mock treatment 597920.0 155000.0 0.87 552250.0 136000.0 0.79 1.1746 0.9986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K14 compound treatment 329530.0 -113000.0 -0.64 357790.0 -58800.0 -0.34 -0.6912 -0.9573 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K15 mock treatment 495910.0 53300.0 0.3 414720.0 -1890.0 -0.01 0.2046 0.6808 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K16 mock treatment 421330.0 -21200.0 -0.12 563840.0 147000.0 0.85 0.5192 0.6022 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K17 compound treatment 352000.0 -90600.0 -0.51 347520.0 -69100.0 -0.4 -0.6439 -0.9929 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K18 compound treatment 422470.0 -20100.0 -0.11 602960.0 186000.0 1.08 0.6842 0.6296 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K19 compound treatment 457170.0 14600.0 0.08 548860.0 132000.0 0.77 0.6004 0.7784 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K20 compound treatment 328520.0 -114000.0 -0.64 339520.0 -77100.0 -0.45 -0.7701 -0.9844 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K21 mock treatment 269660.0 -173000.0 -0.97 443260.0 26700.0 0.15 -0.579 -0.5875 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K22 compound treatment 303840.0 -139000.0 -0.78 300830.0 -116000.0 -0.67 -1.027 -0.9972 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K23 mock treatment 514840.0 72300.0 0.41 534330.0 118000.0 0.68 0.7704 0.9694 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 K24 mock treatment 384200.0 -58400.0 -0.33 338560.0 -78100.0 -0.45 -0.5524 -0.9876 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L01 mock treatment 475200.0 32600.0 0.18 520390.0 104000.0 0.6 0.5555 0.8827 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L02 compound treatment 228490.0 -214000.0 -1.21 253600.0 -163000.0 -0.95 -1.5207 -0.9928 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L03 mock treatment 240890.0 -202000.0 -1.14 549860.0 133000.0 0.77 -0.2564 -0.1867 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L04 mock treatment 567790.0 125000.0 0.7 426130.0 9520.0 0.06 0.5375 0.7602 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L05 compound treatment 434730.0 -7840.0 -0.04 423360.0 6750.0 0.04 -0.0035 -0.0599 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L06 compound treatment 398210.0 -44400.0 -0.25 250810.0 -166000.0 -0.96 -0.8565 -0.8622 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L07 mock treatment 516400.0 73800.0 0.42 436200.0 19600.0 0.11 0.3742 0.8685 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L08 mock treatment 524100.0 81500.0 0.46 519840.0 103000.0 0.6 0.7479 0.9914 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L09 compound treatment 364930.0 -77600.0 -0.44 282990.0 -134000.0 -0.77 -0.857 -0.9633 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L10 compound treatment 395140.0 -47400.0 -0.27 399330.0 -17300.0 -0.1 -0.2597 -0.9105 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L11 compound treatment 340000.0 -103000.0 -0.58 434560.0 18000.0 0.1 -0.3347 -0.5704 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L12 compound treatment 547120.0 105000.0 0.59 346400.0 -70200.0 -0.41 0.1283 0.1792 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L13 compound treatment 18470.0 -424000.0 -2.39 13720.0 -403000.0 -2.34 -3.3404 -0.9999 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L14 compound treatment 13760.0 -429000.0 -2.41 11710.0 -405000.0 -2.35 -3.3674 -0.9999 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L15 mock treatment 470040.0 27500.0 0.15 391970.0 -24600.0 -0.14 0.0083 0.0394 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L16 mock treatment 535380.0 92800.0 0.52 517930.0 101000.0 0.59 0.7849 0.9983 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L17 compound treatment 324110.0 -118000.0 -0.67 350420.0 -66200.0 -0.38 -0.743 -0.9656 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L18 compound treatment 168570.0 -274000.0 -1.54 123390.0 -293000.0 -1.7 -2.2931 -0.9988 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L19 compound treatment 539590.0 97000.0 0.55 374120.0 -42500.0 -0.25 0.212 0.3537 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L20 mock treatment 463040.0 20500.0 0.12 543360.0 127000.0 0.74 0.6013 0.8081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L21 compound treatment 533640.0 91100.0 0.51 531920.0 115000.0 0.67 0.8354 0.9914 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L22 compound treatment 582040.0 139000.0 0.79 538500.0 122000.0 0.71 1.055 0.9986 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L23 mock treatment 359740.0 -82800.0 -0.47 426940.0 10300.0 0.06 -0.2874 -0.6112 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 L24 mock treatment 495730.0 53200.0 0.3 365670.0 -50900.0 -0.3 0.0027 0.0065 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M01 mock treatment 517530.0 75000.0 0.42 519850.0 103000.0 0.6 0.7218 0.9853 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M02 compound treatment 303000.0 -140000.0 -0.79 546530.0 130000.0 0.75 -0.0228 -0.021 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M03 compound treatment 436000.0 -6570.0 -0.04 482420.0 65800.0 0.38 0.2437 0.6356 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M04 compound treatment 302310.0 -140000.0 -0.79 467890.0 51300.0 0.3 -0.348 -0.4125 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M05 compound treatment 443220.0 649.0 0.0 389710.0 -26900.0 -0.16 -0.1077 -0.6904 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M06 compound treatment 351470.0 -91100.0 -0.51 419900.0 3290.0 0.02 -0.3492 -0.6803 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M07 compound treatment 509450.0 66900.0 0.38 277120.0 -139000.0 -0.81 -0.3058 -0.3427 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M08 compound treatment 473860.0 31300.0 0.18 369120.0 -47500.0 -0.28 -0.0702 -0.2147 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M09 mock treatment 442110.0 -461.0 0.0 518790.0 102000.0 0.59 0.4172 0.704 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M10 mock treatment 449530.0 6960.0 0.04 501980.0 85400.0 0.5 0.3778 0.7607 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M11 compound treatment 536050.0 93500.0 0.53 461800.0 45200.0 0.26 0.5574 0.9482 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M12 compound treatment 445000.0 2430.0 0.01 438020.0 21400.0 0.12 0.0975 0.7803 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M13 mock treatment 546110.0 104000.0 0.58 550050.0 133000.0 0.77 0.9594 0.9902 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M14 mock treatment 572800.0 130000.0 0.73 413180.0 -3430.0 -0.02 0.5043 0.6877 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M15 mock treatment 557550.0 115000.0 0.65 442920.0 26300.0 0.15 0.5656 0.8505 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M16 mock treatment 610940.0 168000.0 0.95 598630.0 182000.0 1.06 1.4167 0.9986 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M17 compound treatment 275940.0 -167000.0 -0.94 441440.0 24800.0 0.14 -0.5615 -0.5916 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M18 compound treatment 468240.0 25700.0 0.14 486880.0 70300.0 0.41 0.3903 0.9028 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M19 compound treatment 353500.0 -89100.0 -0.5 561130.0 145000.0 0.84 0.2381 0.2438 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M20 compound treatment 503920.0 61300.0 0.35 498030.0 81400.0 0.47 0.5781 0.9882 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M21 compound treatment 489210.0 46600.0 0.26 398270.0 -18300.0 -0.11 0.1104 0.3899 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M22 compound treatment 542560.0 100000.0 0.56 453570.0 37000.0 0.21 0.5496 0.9125 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M23 compound treatment 404720.0 -37900.0 -0.21 464160.0 47600.0 0.28 0.0443 0.1272 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 M24 compound treatment 277320.0 -165000.0 -0.93 238000.0 -179000.0 -1.04 -1.3903 -0.9986 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N01 compound treatment 275520.0 -167000.0 -0.94 447270.0 30700.0 0.18 -0.5392 -0.5634 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N02 mock treatment 360260.0 -82300.0 -0.46 233470.0 -183000.0 -1.06 -1.0787 -0.9309 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N03 compound treatment 409760.0 -32800.0 -0.18 456730.0 40100.0 0.23 0.0339 0.1142 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N04 compound treatment 184670.0 -258000.0 -1.45 177610.0 -239000.0 -1.39 -2.0067 -0.9997 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N05 compound treatment 249640.0 -193000.0 -1.09 231710.0 -185000.0 -1.07 -1.5262 -1.0 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N06 compound treatment 515740.0 73200.0 0.41 512200.0 95600.0 0.55 0.6833 0.9893 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N07 compound treatment 405630.0 -36900.0 -0.21 460980.0 44400.0 0.26 0.0349 0.1055 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N08 compound treatment 385670.0 -56900.0 -0.32 449010.0 32400.0 0.19 -0.0936 -0.2521 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N09 mock treatment 418250.0 -24300.0 -0.14 411150.0 -5460.0 -0.03 -0.1192 -0.8483 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N10 mock treatment 436100.0 -6470.0 -0.04 375470.0 -41100.0 -0.24 -0.1945 -0.8057 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N11 mock treatment 479730.0 37200.0 0.21 586200.0 170000.0 0.98 0.8434 0.8387 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N12 compound treatment 418680.0 -23900.0 -0.13 287720.0 -129000.0 -0.75 -0.6237 -0.8212 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N13 mock treatment 441250.0 -1320.0 -0.01 414670.0 -1940.0 -0.01 -0.0132 -0.9798 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N14 mock treatment 524160.0 81600.0 0.46 470600.0 54000.0 0.31 0.5462 0.9826 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N15 compound treatment 543960.0 101000.0 0.57 469690.0 53100.0 0.31 0.6213 0.958 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N16 compound treatment 190010.0 -253000.0 -1.42 112530.0 -304000.0 -1.76 -2.2523 -0.9943 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N17 compound treatment 482880.0 40300.0 0.23 514190.0 97600.0 0.57 0.5606 0.9195 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N18 compound treatment 387200.0 -55400.0 -0.31 505760.0 89200.0 0.52 0.1452 0.2405 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N19 compound treatment 583160.0 141000.0 0.79 408660.0 -7950.0 -0.05 0.527 0.6648 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N20 compound treatment 265080.0 -177000.0 -1.0 320070.0 -96500.0 -0.56 -1.1024 -0.9625 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N21 mock treatment 490780.0 48200.0 0.27 439410.0 22800.0 0.13 0.2854 0.9454 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N22 compound treatment 416190.0 -26400.0 -0.15 392430.0 -24200.0 -0.14 -0.2042 -0.9996 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N23 compound treatment 267440.0 -175000.0 -0.99 484860.0 68300.0 0.4 -0.4173 -0.3928 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 N24 mock treatment 376580.0 -66000.0 -0.37 463440.0 46800.0 0.27 -0.0706 -0.1535 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O01 compound treatment 379110.0 -63500.0 -0.36 335540.0 -81100.0 -0.47 -0.5851 -0.9908 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O02 compound treatment 233890.0 -209000.0 -1.17 485290.0 68700.0 0.4 -0.549 -0.4426 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O03 compound treatment 231360.0 -211000.0 -1.19 432370.0 15800.0 0.09 -0.7761 -0.6508 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O04 compound treatment 405690.0 -36900.0 -0.21 320900.0 -95700.0 -0.56 -0.5393 -0.91 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O05 compound treatment 246110.0 -196000.0 -1.11 269060.0 -148000.0 -0.86 -1.3871 -0.992 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O06 compound treatment 379680.0 -62900.0 -0.35 531950.0 115000.0 0.67 0.2226 0.2942 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O07 mock treatment 463860.0 21300.0 0.12 307960.0 -109000.0 -0.63 -0.3608 -0.5625 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O08 mock treatment 484670.0 42100.0 0.24 507140.0 90500.0 0.53 0.5388 0.9354 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O09 mock treatment 439950.0 -2620.0 -0.01 297650.0 -119000.0 -0.69 -0.4983 -0.7221 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O10 compound treatment 520840.0 78300.0 0.44 340260.0 -76400.0 -0.44 -0.0015 -0.0025 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O11 mock treatment 435970.0 -6600.0 -0.04 501280.0 84700.0 0.49 0.3209 0.6517 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O12 mock treatment 549920.0 107000.0 0.6 436230.0 19600.0 0.11 0.5078 0.8257 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O13 compound treatment 26020.0 -417000.0 -2.34 25050.0 -392000.0 -2.27 -3.2639 -0.9999 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O14 compound treatment 30990.0 -412000.0 -2.32 25120.0 -391000.0 -2.27 -3.2438 -0.9999 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O15 compound treatment 595040.0 152000.0 0.86 474030.0 57400.0 0.33 0.8424 0.915 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O16 compound treatment 218760.0 -224000.0 -1.26 133070.0 -284000.0 -1.64 -2.0537 -0.9914 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O17 compound treatment 474270.0 31700.0 0.18 381700.0 -34900.0 -0.2 -0.017 -0.0629 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O18 compound treatment 376160.0 -66400.0 -0.37 325370.0 -91200.0 -0.53 -0.6385 -0.9855 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O19 compound treatment 492920.0 50300.0 0.28 403050.0 -13600.0 -0.08 0.1448 0.4923 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O20 mock treatment 365170.0 -77400.0 -0.44 367470.0 -49100.0 -0.28 -0.5096 -0.9788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O21 mock treatment 577780.0 135000.0 0.76 279680.0 -137000.0 -0.79 -0.0233 -0.0212 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O22 compound treatment 334010.0 -109000.0 -0.61 536320.0 120000.0 0.69 0.0588 0.0635 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O23 compound treatment 290560.0 -152000.0 -0.86 208160.0 -208000.0 -1.21 -1.4599 -0.9857 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 O24 compound treatment 178430.0 -264000.0 -1.49 320640.0 -96000.0 -0.56 -1.445 -0.9101 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P01 compound treatment 393340.0 -49200.0 -0.28 299250.0 -117000.0 -0.68 -0.6772 -0.9216 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P02 mock treatment 384800.0 -57800.0 -0.33 243960.0 -173000.0 -1.0 -0.938 -0.891 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P03 mock treatment 246140.0 -196000.0 -1.11 246560.0 -170000.0 -0.99 -1.4793 -0.9984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P04 compound treatment 319040.0 -124000.0 -0.7 240760.0 -176000.0 -1.02 -1.2129 -0.9826 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P05 compound treatment 208030.0 -235000.0 -1.32 311320.0 -105000.0 -0.61 -1.3654 -0.9386 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P06 compound treatment 245670.0 -197000.0 -1.11 234830.0 -182000.0 -1.05 -1.5292 -0.9997 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P07 compound treatment 341760.0 -101000.0 -0.57 270840.0 -146000.0 -0.85 -0.9991 -0.9812 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P08 compound treatment 307170.0 -135000.0 -0.76 352400.0 -64200.0 -0.37 -0.8023 -0.9457 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P09 mock treatment 336510.0 -106000.0 -0.6 272160.0 -144000.0 -0.84 -1.0146 -0.9862 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P10 compound treatment 374320.0 -68300.0 -0.38 427790.0 11200.0 0.06 -0.2258 -0.5796 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P11 mock treatment 410690.0 -31900.0 -0.18 312120.0 -104000.0 -0.61 -0.5554 -0.8788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P12 mock treatment 340250.0 -102000.0 -0.58 357710.0 -58900.0 -0.34 -0.6488 -0.9689 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P13 compound treatment 375120.0 -67500.0 -0.38 344850.0 -71800.0 -0.42 -0.5628 -0.999 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P14 compound treatment 20850.0 -422000.0 -2.37 18130.0 -398000.0 -2.31 -3.3128 -0.9999 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P15 compound treatment 345120.0 -97500.0 -0.55 402850.0 -13800.0 -0.08 -0.4443 -0.8015 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P16 compound treatment 295610.0 -147000.0 -0.83 380530.0 -36100.0 -0.21 -0.733 -0.8589 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P17 compound treatment 303170.0 -139000.0 -0.78 306130.0 -110000.0 -0.64 -1.008 -0.9949 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P18 compound treatment 252340.0 -190000.0 -1.07 392850.0 -23800.0 -0.14 -0.8547 -0.7916 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P19 compound treatment 279730.0 -163000.0 -0.92 273390.0 -143000.0 -0.83 -1.2355 -0.9988 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P20 mock treatment 492530.0 50000.0 0.28 349710.0 -66900.0 -0.39 -0.0755 -0.1575 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P21 compound treatment 273440.0 -169000.0 -0.95 263490.0 -153000.0 -0.89 -1.3012 -0.9994 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P22 compound treatment 121600.0 -321000.0 -1.81 214890.0 -202000.0 -1.17 -2.1049 -0.9779 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P23 compound treatment 235790.0 -207000.0 -1.16 328880.0 -87700.0 -0.51 -1.1829 -0.9311 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.2284 P24 mock treatment 287810.0 -155000.0 -0.87 257700.0 -159000.0 -0.92 -1.2677 -0.9996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A01 mock treatment 468160.0 101000.0 0.57 177530.0 -217000.0 -1.26 -0.6141 -0.4008 387570.0 -119533.84 -0.656070672970078 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A02 mock treatment 378470.0 11600.0 0.07 408900.0 14700.0 0.09 -0.38 -0.4696 362530.0 -144573.84 -0.793504638541423 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A03 mock treatment 311420.0 -55400.0 -0.31 166830.0 -227000.0 -1.32 -1.5176 -0.8631 445950.0 -61153.84 -0.335647553558929 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A04 mock treatment 198080.0 -169000.0 -0.95 188160.0 -206000.0 -1.19 -2.2912 -0.9833 331230.0 -175873.84 -0.965297095505605 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A05 mock treatment 173460.0 -193000.0 -1.09 472030.0 77800.0 0.45 -1.4672 -0.7137 240330.0 -266773.84 -1.46420873569871 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A06 mock treatment 460060.0 93200.0 0.52 142410.0 -252000.0 -1.46 -1.5891 -0.7157 313570.0 -193533.84 -1.06222536355632 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A07 mock treatment 168640.0 -198000.0 -1.12 240570.0 -154000.0 -0.89 -1.7258 -0.9674 334800.0 -172303.84 -0.945702875973269 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A08 mock treatment 194080.0 -173000.0 -0.97 194970.0 -199000.0 -1.16 -0.9185 -0.5942 500420.0 -6683.84000000003 -0.0366847698260538 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A09 mock treatment 229320.0 -138000.0 -0.77 187000.0 -207000.0 -1.2 -0.9162 -0.5718 427800.0 -79303.84 -0.435265224290555 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A10 mock treatment 236060.0 -131000.0 -0.74 195570.0 -199000.0 -1.15 -1.8786 -0.9879 340100.0 -167003.84 -0.916613418404254 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A11 mock treatment 298490.0 -68400.0 -0.38 234810.0 -159000.0 -0.92 -1.5048 -0.9617 353850.0 -153253.84 -0.84114548603181 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A12 mock treatment 453700.0 86900.0 0.49 204660.0 -190000.0 -1.1 -0.8437 -0.5923 414740.0 -92363.84 -0.506946038602128 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A13 mock treatment 154420.0 -212000.0 -1.2 207130.0 -187000.0 -1.08 -1.4068 -0.8412 486690.0 -20413.84 -0.112042930660502 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A14 mock treatment 254140.0 -113000.0 -0.63 365700.0 -28500.0 -0.17 -1.1042 -0.9247 386760.0 -120343.84 -0.660516420258927 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A15 mock treatment 257760.0 -109000.0 -0.61 440540.0 46400.0 0.27 -0.8648 -0.589 269540.0 -237563.84 -1.30388740445514 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A16 mock treatment 347150.0 -19700.0 -0.11 312120.0 -82100.0 -0.48 -1.0253 -0.8937 383700.0 -123403.84 -0.677311465572358 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A17 mock treatment 319410.0 -47400.0 -0.27 311230.0 -83000.0 -0.48 -0.2536 -0.4387 522790.0 15686.16 0.0860946954227882 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A18 mock treatment 338890.0 -28000.0 -0.16 440800.0 46600.0 0.27 0.1815 0.4856 543160.0 36056.16 0.197897006872002 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A19 mock treatment 263810.0 -103000.0 -0.58 278750.0 -115000.0 -0.67 -1.3748 -0.8786 465020.0 -42083.84 -0.230980392079474 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A20 mock treatment 344180.0 -22700.0 -0.13 334580.0 -59600.0 -0.35 -0.3811 -0.5595 411840.0 -95263.84 -0.522862911611589 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A21 mock treatment 434560.0 67700.0 0.38 334360.0 -59800.0 -0.35 0.0267 0.0469 539840.0 32736.16 0.179674931564619 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A22 mock treatment 330490.0 -36400.0 -0.2 350830.0 -43400.0 -0.25 -1.0512 -0.8514 324510.0 -182593.84 -1.00218033227236 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A23 mock treatment 385920.0 19100.0 0.11 441600.0 47400.0 0.27 0.6324 0.7969 537070.0 29966.16 0.164471573552134 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base A24 mock treatment 295080.0 -71800.0 -0.4 241240.0 -153000.0 -0.89 -0.3852 -0.3684 566240.0 59136.16 0.324573361719712 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B01 mock treatment 464730.0 97900.0 0.55 442240.0 48100.0 0.28 0.8296 0.9671 595920.0 88816.16 0.487474324106195 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B02 mock treatment 430450.0 63600.0 0.36 482270.0 88100.0 0.51 0.9555 0.979 583620.0 76516.16 0.419964828238481 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B03 mock treatment 492440.0 126000.0 0.71 350530.0 -43700.0 -0.25 0.3041 0.2747 625000.0 117896.16 0.64708214035279 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B04 mock treatment 406240.0 39400.0 0.22 319090.0 -75100.0 -0.44 -0.0971 -0.0661 687250.0 180146.16 0.988746052366219 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B05 mock treatment 225960.0 -141000.0 -0.79 453860.0 59700.0 0.35 0.1795 0.1652 622650.0 115546.16 0.634183984638227 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B06 mock treatment 357120.0 -9720.0 -0.05 468120.0 73900.0 0.43 0.6599 0.6837 663530.0 156426.16 0.858557008302628 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B07 mock treatment 457770.0 90900.0 0.51 477810.0 83600.0 0.48 0.0854 0.0901 463750.0 -43353.84 -0.237950884742238 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B08 mock treatment 472900.0 106000.0 0.6 430600.0 36400.0 0.21 0.9719 0.9199 644750.0 137646.16 0.755481534124119 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B09 mock treatment 405600.0 38800.0 0.22 412010.0 17800.0 0.1 0.2016 0.3481 447140.0 -59963.84 -0.32911614704815 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B10 mock treatment 344510.0 -22300.0 -0.13 453210.0 59000.0 0.34 0.2328 0.4954 499070.0 -8033.84000000003 -0.0440943486408028 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B11 mock treatment 510330.0 143000.0 0.81 447420.0 53200.0 0.31 0.1319 0.0825 274630.0 -232473.84 -1.27595054803508 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B12 mock treatment 525440.0 159000.0 0.89 276690.0 -117000.0 -0.68 -0.0625 -0.0521 520650.0 13546.16 0.074349140857186 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B13 mock treatment 352600.0 -14200.0 -0.08 518260.0 124000.0 0.72 0.6069 0.7146 582560.0 75456.16 0.414146936724678 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B14 mock treatment 283000.0 -83800.0 -0.47 485150.0 91000.0 0.53 0.2417 0.2611 479840.0 -27263.84 -0.149639682424228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B15 mock treatment 466510.0 99700.0 0.56 369000.0 -25200.0 -0.15 0.3103 0.2812 645350.0 138246.16 0.758774680264007 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B16 mock treatment 512250.0 145000.0 0.82 475640.0 81500.0 0.47 0.689 0.7114 488900.0 -18203.84 -0.0999131757119125 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B17 mock treatment 461020.0 94200.0 0.53 391860.0 -2330.0 -0.01 0.3372 0.3921 435450.0 -71653.84 -0.393277611006977 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B18 mock treatment 282320.0 -84500.0 -0.48 452530.0 58300.0 0.34 0.3917 0.4206 549730.0 42626.16 0.233956957103781 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B19 mock treatment 398500.0 31700.0 0.18 490400.0 96200.0 0.56 0.7577 0.8491 528260.0 21156.16 0.116117211064771 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B20 mock treatment 271300.0 -95500.0 -0.54 395230.0 1040.0 0.01 0.1388 0.1728 559000.0 51896.16 0.284836064965058 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B21 mock treatment 223520.0 -143000.0 -0.81 451730.0 57500.0 0.33 0.1757 0.1649 606000.0 98896.16 0.542799179256321 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B22 mock treatment 306720.0 -60100.0 -0.34 297360.0 -96800.0 -0.56 -0.4697 -0.7127 511380.0 4276.15999999997 0.023470032995909 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B23 mock treatment 212580.0 -154000.0 -0.87 450780.0 56600.0 0.33 -0.3205 -0.2661 596390.0 89286.16 0.490053955249108 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base B24 mock treatment 411320.0 44500.0 0.25 384100.0 -10100.0 -0.06 0.2235 0.2955 441710.0 -65393.84 -0.358919119614141 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C01 mock treatment 225920.0 -141000.0 -0.79 383840.0 -10300.0 -0.06 -0.687 -0.5487 574830.0 67726.16 0.371720237289115 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C02 mock treatment 349200.0 -17600.0 -0.1 382210.0 -12000.0 -0.07 0.1718 0.3452 594880.0 87776.16 0.481766204130388 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C03 mock treatment 209250.0 -158000.0 -0.89 405310.0 11100.0 0.06 -0.51 -0.5626 502760.0 -4343.84000000003 -0.0238414998804887 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C04 mock treatment 291290.0 -75600.0 -0.43 224050.0 -170000.0 -0.99 -1.2072 -0.7603 535560.0 28456.16 0.156183822433415 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C05 mock treatment 228020.0 -139000.0 -0.78 419150.0 25000.0 0.14 -0.9185 -0.6039 524090.0 16986.16 0.0932298453925465 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C06 mock treatment 414340.0 47500.0 0.27 325600.0 -68600.0 -0.4 -0.1674 -0.2589 435780.0 -71323.84 -0.391466380630039 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C07 mock treatment 407150.0 40300.0 0.23 359680.0 -34500.0 -0.2 0.1136 0.2904 551580.0 44476.16 0.244110824368437 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C08 mock treatment 445050.0 78200.0 0.44 311600.0 -82600.0 -0.48 -0.2578 -0.2897 528740.0 21636.16 0.118751727976682 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C09 mock treatment 430510.0 63700.0 0.36 441770.0 47600.0 0.28 0.0419 0.066 485220.0 -21883.84 -0.120111138703228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C10 mock treatment 346170.0 -20700.0 -0.12 418100.0 23900.0 0.14 -0.4 -0.4245 524830.0 17726.16 0.097291392298409 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C11 mock treatment 391200.0 24400.0 0.14 386890.0 -7300.0 -0.04 0.183 0.4336 576590.0 69486.16 0.381380132632788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C12 mock treatment 466750.0 99900.0 0.56 260860.0 -133000.0 -0.77 -0.563 -0.484 441870.0 -65233.84 -0.358040947310171 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C13 mock treatment 222470.0 -144000.0 -0.81 378570.0 -15600.0 -0.09 -0.0701 -0.0708 558040.0 50936.16 0.279567031141236 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C14 mock treatment 413920.0 47100.0 0.27 411870.0 17700.0 0.1 0.5926 0.88 556320.0 49216.16 0.270126678873556 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C15 mock treatment 322260.0 -44600.0 -0.25 362340.0 -31800.0 -0.18 -0.054 -0.1209 565460.0 58356.16 0.320292271737857 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C16 mock treatment 237800.0 -129000.0 -0.73 287400.0 -107000.0 -0.62 -0.7203 -0.6788 439380.0 -67723.84 -0.371707503790708 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C17 mock treatment 352400.0 -14400.0 -0.08 413760.0 19600.0 0.11 0.4055 0.6709 551490.0 44386.16 0.243616852447454 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C18 mock treatment 241310.0 -126000.0 -0.71 345570.0 -48600.0 -0.28 -0.8072 -0.8592 407770.0 -99333.84 -0.545201419593832 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C19 mock treatment 302530.0 -64300.0 -0.36 280640.0 -114000.0 -0.66 -0.2585 -0.308 538400.0 31296.16 0.171771380828887 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C20 mock treatment 213560.0 -153000.0 -0.86 271300.0 -123000.0 -0.71 -0.9794 -0.7774 538030.0 30926.16 0.169740607375955 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C21 mock treatment 311550.0 -55300.0 -0.31 279950.0 -114000.0 -0.66 -0.4103 -0.5493 507890.0 786.159999999974 0.00431489961555773 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C22 mock treatment 442510.0 75700.0 0.43 247200.0 -147000.0 -0.85 0.162 0.1481 585280.0 78176.16 0.429075865892173 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C23 mock treatment 328040.0 -38800.0 -0.22 296890.0 -97300.0 -0.56 -0.6271 -0.8497 497610.0 -9493.84000000003 -0.0521076709145315 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base C24 mock treatment 311120.0 -55700.0 -0.31 256220.0 -138000.0 -0.8 -0.5561 -0.6236 537850.0 30746.16 0.168752663533989 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D01 mock treatment 429850.0 63000.0 0.35 481870.0 87700.0 0.51 0.8333 0.9688 556970.0 49866.16 0.273694253858435 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D02 mock treatment 366720.0 -123.0 0.0 360050.0 -34100.0 -0.2 0.1798 0.2791 618370.0 111266.16 0.610692875507022 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D03 mock treatment 369990.0 3150.0 0.02 374480.0 -19700.0 -0.11 0.369 0.5837 608240.0 101136.16 0.555093591511905 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D04 mock treatment 465470.0 98600.0 0.56 321150.0 -73000.0 -0.42 0.4981 0.5349 595600.0 88496.16 0.485717979498255 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D05 mock treatment 432160.0 65300.0 0.37 339210.0 -55000.0 -0.32 -0.4129 -0.5067 454650.0 -52453.84 -0.287896934530546 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D06 mock treatment 480330.0 113000.0 0.64 352750.0 -41400.0 -0.24 0.5937 0.6464 612200.0 105096.16 0.576828356035169 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D07 mock treatment 354880.0 -12000.0 -0.07 429930.0 35700.0 0.21 0.246 0.3561 617290.0 110186.16 0.604765212455223 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D08 mock treatment 327040.0 -39800.0 -0.22 441840.0 47700.0 0.28 -0.1632 -0.1872 569180.0 62076.16 0.340709777805165 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D09 mock treatment 343360.0 -23500.0 -0.13 480160.0 86000.0 0.5 0.3742 0.4801 608650.0 101546.16 0.557343908040829 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D10 mock treatment 448760.0 81900.0 0.46 473520.0 79300.0 0.46 0.4344 0.446 409180.0 -97923.84 -0.537462526165094 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D11 mock treatment 424020.0 57200.0 0.32 447470.0 53300.0 0.31 -0.2964 -0.2816 344130.0 -162973.84 -0.894494453498003 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D12 mock treatment 299890.0 -67000.0 -0.38 400870.0 6680.0 0.04 0.1368 0.1959 511790.0 4686.15999999997 0.0257203495248328 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D13 mock treatment 357600.0 -9240.0 -0.05 435360.0 41200.0 0.24 0.5572 0.7887 579360.0 72256.16 0.396583490645273 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D14 mock treatment 272810.0 -94000.0 -0.53 485460.0 91300.0 0.53 0.5014 0.4838 611920.0 104816.16 0.575291554503221 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D15 mock treatment 431110.0 64300.0 0.36 444800.0 50600.0 0.29 -0.0805 -0.0717 324230.0 -182873.84 -1.0037171338043 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D16 mock treatment 376420.0 9580.0 0.05 395780.0 1590.0 0.01 -0.0473 -0.0695 578880.0 71776.16 0.393948973733362 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D17 mock treatment 255250.0 -112000.0 -0.63 462080.0 67900.0 0.39 0.4791 0.4135 578900.0 71796.16 0.394058745271359 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D18 mock treatment 454660.0 87800.0 0.49 396160.0 1970.0 0.01 0.018 0.0274 500190.0 -6913.84000000003 -0.037947142513011 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D19 mock treatment 356800.0 -10000.0 -0.06 302300.0 -91900.0 -0.53 0.1573 0.183 616290.0 109186.16 0.599276635555409 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D20 mock treatment 241120.0 -126000.0 -0.71 280740.0 -113000.0 -0.66 -0.7802 -0.7334 543880.0 36776.16 0.201848782239868 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D21 mock treatment 275080.0 -91800.0 -0.52 322300.0 -71900.0 -0.42 -0.5674 -0.8319 497200.0 -9903.84000000003 -0.0543579874434553 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D22 mock treatment 274690.0 -92200.0 -0.52 397760.0 3570.0 0.02 -0.3517 -0.5321 537670.0 30566.16 0.167764719692022 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D23 mock treatment 326080.0 -40800.0 -0.23 299920.0 -94300.0 -0.55 -0.0593 -0.0763 542560.0 35456.16 0.194603860732113 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base D24 mock treatment 168580.0 -198000.0 -1.12 419110.0 24900.0 0.14 -0.2727 -0.231 570600.0 63496.16 0.348503557002901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E01 mock treatment 355050.0 -11800.0 -0.07 457820.0 63600.0 0.37 -0.0677 -0.0586 602120.0 95016.16 0.521503500885043 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E02 mock treatment 399370.0 32500.0 0.18 465340.0 71200.0 0.41 0.4899 0.8685 568050.0 60946.16 0.334507685908375 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E03 mock treatment 416640.0 49800.0 0.28 487460.0 93300.0 0.54 0.9479 0.9287 644340.0 137236.16 0.753231217595195 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E04 mock treatment 297080.0 -69800.0 -0.39 196760.0 -197000.0 -1.14 -0.9671 -0.5986 337970.0 -169133.84 -0.928304087200858 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E05 mock treatment 246450.0 -120000.0 -0.68 464070.0 69900.0 0.41 -0.1141 -0.1325 555220.0 48116.16 0.26408924428376 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E06 mock treatment 451560.0 84700.0 0.48 364670.0 -29500.0 -0.17 0.378 0.3768 444420.0 -62683.84 -0.344045076215645 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E07 mock treatment 444170.0 77300.0 0.44 485090.0 90900.0 0.53 0.6142 0.6138 440350.0 -66753.84 -0.366383584197888 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E08 mock treatment 463240.0 96400.0 0.54 476500.0 82300.0 0.48 0.1164 0.0693 253940.0 -253163.84 -1.38950920409224 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E09 mock treatment 468650.0 102000.0 0.57 521300.0 127000.0 0.74 1.1182 0.9743 574900.0 67796.16 0.372104437672102 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E10 mock treatment 304060.0 -62800.0 -0.35 440540.0 46400.0 0.27 0.1286 0.1842 600320.0 93216.16 0.511624062465377 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E11 mock treatment 483200.0 116000.0 0.66 481630.0 87400.0 0.51 1.0251 0.9653 560010.0 52906.16 0.29037952763387 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E12 mock treatment 508760.0 142000.0 0.8 496480.0 102000.0 0.59 0.9292 0.856 513280.0 6176.15999999997 0.0338983291055559 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E13 mock treatment 436450.0 69600.0 0.39 389810.0 -4380.0 -0.03 0.1659 0.257 438020.0 -69083.84 -0.379171968374455 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E14 mock treatment 481920.0 115000.0 0.65 469490.0 75300.0 0.44 0.7464 0.8636 514560.0 7456.15999999997 0.0409237075373179 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E15 mock treatment 410720.0 43900.0 0.25 514740.0 121000.0 0.7 0.8011 0.9038 548360.0 41256.16 0.226437606751035 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E16 mock treatment 379420.0 12600.0 0.07 463730.0 69500.0 0.4 0.1186 0.258 501650.0 -5453.84000000003 -0.0299338202392824 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E17 mock treatment 503040.0 136000.0 0.77 387740.0 -6450.0 -0.04 0.7991 0.8124 589940.0 82836.16 0.454652634245307 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E18 mock treatment 464000.0 97200.0 0.55 547940.0 154000.0 0.89 0.8576 0.6021 410350.0 -96753.84 -0.531040891192312 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E19 mock treatment 411370.0 44500.0 0.25 312190.0 -82000.0 -0.48 0.359 0.417 581540.0 74436.16 0.408548588286868 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E20 mock treatment 425930.0 59100.0 0.33 362650.0 -31500.0 -0.18 -0.0251 -0.0582 469710.0 -37393.84 -0.205238966419346 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E21 mock treatment 329610.0 -37200.0 -0.21 448190.0 54000.0 0.31 0.0954 0.2374 531230.0 24126.16 0.132418284457219 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E22 mock treatment 286400.0 -80400.0 -0.45 427040.0 32900.0 0.19 -0.1543 -0.2754 537310.0 30206.16 0.165788832008089 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E23 mock treatment 436800.0 70000.0 0.39 295710.0 -98500.0 -0.57 -0.0608 -0.0862 528320.0 21216.16 0.11644652567876 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base E24 mock treatment 320920.0 -45900.0 -0.26 340190.0 -54000.0 -0.31 -0.5234 -0.5424 359700.0 -147403.84 -0.809037311167897 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F01 mock treatment 484170.0 117000.0 0.66 468930.0 74700.0 0.43 0.6506 0.7648 561960.0 54856.16 0.301082252588507 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F02 mock treatment 385920.0 19100.0 0.11 405370.0 11200.0 0.06 -1.2214 -0.659 269520.0 -237583.84 -1.30399717599314 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F03 mock treatment 230690.0 -136000.0 -0.77 272810.0 -121000.0 -0.7 -0.5503 -0.4972 505920.0 -1183.84000000003 -0.00649759687707609 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F04 mock treatment 245200.0 -122000.0 -0.68 228330.0 -166000.0 -0.96 -0.7235 -0.5287 612550.0 105446.16 0.578749357950104 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F05 mock treatment 226120.0 -141000.0 -0.79 505780.0 112000.0 0.65 -0.7401 -0.3972 225870.0 -281233.84 -1.54357355767002 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F06 mock treatment 387380.0 20500.0 0.12 199970.0 -194000.0 -1.13 -0.0704 -0.0475 492090.0 -15013.84 -0.0824046154015054 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F07 mock treatment 485440.0 119000.0 0.67 430880.0 36700.0 0.21 -0.1725 -0.1258 498320.0 -8783.84000000003 -0.0482107813156634 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F08 mock treatment 274300.0 -92500.0 -0.52 484850.0 90700.0 0.53 0.7397 0.5769 653820.0 146716.16 0.805262926605433 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F09 mock treatment 397950.0 31100.0 0.18 410350.0 16200.0 0.09 0.3099 0.4294 622560.0 115456.16 0.633690012717243 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F10 mock treatment 518500.0 152000.0 0.85 346720.0 -47500.0 -0.28 -0.1122 -0.0968 493720.0 -13383.84 -0.0734582350548084 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F11 mock treatment 287040.0 -79800.0 -0.45 519530.0 125000.0 0.73 0.4101 0.3438 461370.0 -45733.84 -0.251013697763795 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F12 mock treatment 346280.0 -20600.0 -0.12 312160.0 -82000.0 -0.48 -0.4302 -0.4961 393700.0 -113403.84 -0.622425696574217 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F13 mock treatment 346240.0 -20600.0 -0.12 360260.0 -33900.0 -0.2 0.0511 0.0698 463680.0 -43423.84 -0.238335085125225 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F14 mock treatment 246920.0 -120000.0 -0.68 259680.0 -135000.0 -0.78 -0.7186 -0.5142 630170.0 123066.16 0.675458082924829 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F15 mock treatment 274040.0 -92800.0 -0.52 321280.0 -72900.0 -0.42 -0.5363 -0.7628 519410.0 12306.16 0.0675433055014164 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F16 mock treatment 380960.0 14100.0 0.08 415430.0 21200.0 0.12 0.3297 0.7925 520710.0 13606.16 0.0746784554711748 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F17 mock treatment 352860.0 -14000.0 -0.08 471840.0 77700.0 0.45 0.076 0.1572 484830.0 -22273.84 -0.122251683694156 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F18 mock treatment 339880.0 -27000.0 -0.15 401920.0 7730.0 0.04 0.5253 0.6268 601480.0 94376.16 0.517990811669162 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F19 mock treatment 367330.0 487.0 0.0 378470.0 -15700.0 -0.09 0.4829 0.611 571440.0 64336.16 0.353113961598745 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F20 mock treatment 341850.0 -25000.0 -0.14 392980.0 -1210.0 -0.01 0.0218 0.0611 486000.0 -21103.84 -0.115830048721373 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F21 mock treatment 262620.0 -104000.0 -0.59 379700.0 -14500.0 -0.08 0.2942 0.2736 607520.0 100416.16 0.551141816144039 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F22 mock treatment 297530.0 -69300.0 -0.39 440860.0 46700.0 0.27 -0.2463 -0.2432 363010.0 -144093.84 -0.790870121629513 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F23 mock treatment 414990.0 48100.0 0.27 395640.0 1450.0 0.01 0.0733 0.2317 512090.0 4986.15999999997 0.0273669225947771 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base F24 mock treatment 324490.0 -42400.0 -0.24 313490.0 -80700.0 -0.47 -0.3642 -0.6743 521190.0 14086.16 0.0773129723830856 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G01 mock treatment 389800.0 23000.0 0.13 297250.0 -96900.0 -0.56 -1.1137 -0.7974 332210.0 -174893.84 -0.959918290143788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G02 mock treatment 491320.0 124000.0 0.7 426300.0 32100.0 0.19 1.1206 0.9198 604260.0 97156.16 0.533249055450645 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G03 mock treatment 234560.0 -132000.0 -0.74 492010.0 97800.0 0.57 0.0064 0.0068 538560.0 31456.16 0.172649553132857 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G04 mock treatment 510090.0 143000.0 0.81 220640.0 -174000.0 -1.01 -0.2683 -0.1707 588050.0 80946.16 0.444279223904658 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G05 mock treatment 228130.0 -139000.0 -0.78 495110.0 101000.0 0.59 -1.0846 -0.6256 285440.0 -221663.84 -1.21661903174809 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G06 mock treatment 488980.0 122000.0 0.69 447780.0 53600.0 0.31 0.6695 0.5118 404000.0 -103103.84 -0.565893354506132 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G07 mock treatment 289530.0 -77300.0 -0.44 499880.0 106000.0 0.61 -0.6687 -0.4955 411480.0 -95623.84 -0.524838799295522 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G08 mock treatment 461660.0 94800.0 0.53 504410.0 110000.0 0.64 -0.2028 -0.1437 334040.0 -173063.84 -0.949874194417128 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G09 mock treatment 266050.0 -101000.0 -0.57 400960.0 6770.0 0.04 -0.0801 -0.0943 466690.0 -40413.84 -0.221814468656784 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G10 mock treatment 290400.0 -76400.0 -0.43 437800.0 43600.0 0.25 0.2049 0.2946 528500.0 21396.16 0.117434469520727 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G11 mock treatment 232800.0 -134000.0 -0.75 368230.0 -26000.0 -0.15 -1.1883 -0.9158 385250.0 -121853.84 -0.668804171377646 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G12 mock treatment 337890.0 -29000.0 -0.16 485600.0 91400.0 0.53 -1.2565 -0.5917 214900.0 -292203.84 -1.60378324626098 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G13 mock treatment 347140.0 -19700.0 -0.11 232880.0 -161000.0 -0.94 -0.2052 -0.1345 421760.0 -85343.84 -0.468416228765433 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G14 mock treatment 377280.0 10400.0 0.06 434400.0 40200.0 0.23 0.5086 0.7425 622810.0 115706.16 0.635062156942197 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G15 mock treatment 466720.0 99900.0 0.56 367450.0 -26700.0 -0.16 -0.2422 -0.2779 444930.0 -62173.84 -0.34124590199674 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G16 mock treatment 425350.0 58500.0 0.33 278960.0 -115000.0 -0.67 0.3597 0.2803 509600.0 2496.15999999997 0.0137003661142399 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G17 mock treatment 469150.0 102000.0 0.58 401400.0 7210.0 0.04 0.198 0.2501 553650.0 46546.16 0.255472178551052 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G18 mock treatment 447840.0 81000.0 0.46 400710.0 6520.0 0.04 0.5659 0.6401 486990.0 -20113.84 -0.110396357590557 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G19 mock treatment 330090.0 -36800.0 -0.21 326020.0 -68200.0 -0.4 -0.1113 -0.1489 610790.0 103686.16 0.569089462606431 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G20 mock treatment 370100.0 3260.0 0.02 459360.0 65200.0 0.38 0.3581 0.7504 559760.0 52656.16 0.289007383408916 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G21 mock treatment 382880.0 16000.0 0.09 486880.0 92700.0 0.54 0.8331 0.8944 578850.0 71746.16 0.393784316426368 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G22 mock treatment 478000.0 111000.0 0.63 390620.0 -3570.0 -0.02 -0.0595 -0.0407 283940.0 -223163.84 -1.22485189709782 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G23 mock treatment 376610.0 9770.0 0.05 357970.0 -36200.0 -0.21 -0.0223 -0.031 604910.0 97806.16 0.536816630435524 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base G24 mock treatment 219900.0 -147000.0 -0.83 259530.0 -135000.0 -0.78 -0.9401 -0.8148 480800.0 -26303.84 -0.144370648600407 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H01 mock treatment 331040.0 -35800.0 -0.2 405640.0 11500.0 0.07 0.403 0.5769 594370.0 87266.16 0.478967029911483 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H02 mock treatment 291860.0 -75000.0 -0.42 492200.0 98000.0 0.57 0.3889 0.4644 567790.0 60686.16 0.333080655914424 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H03 mock treatment 281120.0 -85700.0 -0.48 494960.0 101000.0 0.58 -0.4343 -0.3853 479840.0 -27263.84 -0.149639682424228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H04 mock treatment 363540.0 -3300.0 -0.02 482960.0 88800.0 0.51 0.5152 0.7955 569480.0 62376.16 0.34235635087511 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H05 mock treatment 249970.0 -117000.0 -0.66 350980.0 -43200.0 -0.25 -0.9864 -0.8453 339650.0 -167453.84 -0.919083278009171 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H06 mock treatment 256160.0 -111000.0 -0.62 357250.0 -36900.0 -0.21 -0.2609 -0.3184 480110.0 -26993.84 -0.148157766661279 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H07 mock treatment 249860.0 -117000.0 -0.66 262880.0 -131000.0 -0.76 -0.6407 -0.6255 540530.0 33426.16 0.183462049625491 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H08 mock treatment 372160.0 5320.0 0.03 340670.0 -53500.0 -0.31 0.2589 0.4014 581600.0 74496.16 0.408877902900857 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H09 mock treatment 497210.0 130000.0 0.73 384370.0 -9820.0 -0.06 -0.4918 -0.3104 256850.0 -250253.84 -1.37353744531378 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H10 mock treatment 478240.0 111000.0 0.63 393610.0 -579.0 0.0 0.3858 0.4543 593130.0 86026.16 0.472161194555714 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H11 mock treatment 189010.0 -178000.0 -1.0 269670.0 -125000.0 -0.72 -0.2314 -0.152 617130.0 110026.16 0.603887040151253 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H12 mock treatment 241600.0 -125000.0 -0.71 534890.0 141000.0 0.82 0.1458 0.1168 444210.0 -62893.84 -0.345197677364606 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H13 mock treatment 356450.0 -10400.0 -0.06 180850.0 -213000.0 -1.24 -1.4874 -0.8662 362880.0 -144223.84 -0.791583636626488 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H14 mock treatment 174200.0 -193000.0 -1.08 376580.0 -17600.0 -0.1 -0.9827 -0.7782 394470.0 -112633.84 -0.61819949236136 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H15 mock treatment 413020.0 46200.0 0.26 303690.0 -90500.0 -0.52 -0.9245 -0.6841 301230.0 -205873.84 -1.12995440250003 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H16 mock treatment 439570.0 72700.0 0.41 264160.0 -130000.0 -0.75 -0.0978 -0.1099 493300.0 -13803.84 -0.0757634373527303 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H17 mock treatment 253770.0 -113000.0 -0.64 376800.0 -17400.0 -0.1 -0.4298 -0.6556 506690.0 -413.840000000026 -0.00227139266421922 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H18 mock treatment 382830.0 16000.0 0.09 415330.0 21100.0 0.12 -0.1226 -0.1581 554050.0 46946.16 0.257667609310978 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H19 mock treatment 511920.0 145000.0 0.82 411440.0 17300.0 0.1 0.9283 0.8612 619480.0 112376.16 0.616785195865816 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H20 mock treatment 477120.0 110000.0 0.62 453850.0 59700.0 0.35 0.4942 0.6563 541030.0 33926.16 0.186206338075398 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H21 mock treatment 416400.0 49600.0 0.28 398190.0 4000.0 0.02 -0.0918 -0.1051 365950.0 -141153.84 -0.774733705544059 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H22 mock treatment 422480.0 55600.0 0.31 465120.0 70900.0 0.41 0.299 0.408 429660.0 -77443.84 -0.425056471256901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H23 mock treatment 408060.0 41200.0 0.23 408160.0 14000.0 0.08 0.3566 0.8813 523900.0 16796.16 0.0921870157815819 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base H24 mock treatment 397020.0 30200.0 0.17 261050.0 -133000.0 -0.77 -0.6348 -0.5887 518620.0 11516.16 0.0632073297505633 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I01 mock treatment 369850.0 3010.0 0.02 424430.0 30200.0 0.18 0.6487 0.6949 546030.0 38926.16 0.213649222574468 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I02 mock treatment 485610.0 119000.0 0.67 274520.0 -120000.0 -0.69 0.3296 0.3018 591610.0 84506.16 0.463818557667996 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I03 mock treatment 437500.0 70700.0 0.4 362940.0 -31200.0 -0.18 -0.3803 -0.4649 414810.0 -92293.84 -0.506561838219141 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I04 mock treatment 274990.0 -91900.0 -0.52 353080.0 -41100.0 -0.24 0.0603 0.0716 583220.0 76116.16 0.417769397478556 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I05 mock treatment 232180.0 -135000.0 -0.76 482180.0 88000.0 0.51 -0.7833 -0.588 421080.0 -86023.84 -0.472148461057306 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I06 mock treatment 438080.0 71200.0 0.4 432100.0 37900.0 0.22 0.1998 0.2237 583720.0 76616.16 0.420513685928463 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I07 mock treatment 241620.0 -125000.0 -0.7 394920.0 731.0 0.0 -1.3266 -0.8558 330020.0 -177083.84 -0.971938273554381 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I08 mock treatment 454880.0 88000.0 0.5 490200.0 96000.0 0.56 0.4754 0.4053 614150.0 107046.16 0.587531080989807 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I09 mock treatment 476900.0 110000.0 0.62 506150.0 112000.0 0.65 1.1479 0.8815 523040.0 15936.16 0.0874668396477417 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I10 mock treatment 444190.0 77300.0 0.44 410850.0 16700.0 0.1 0.2549 0.2737 399790.0 -107313.84 -0.589000263254349 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I11 mock treatment 477760.0 111000.0 0.62 340000.0 -54200.0 -0.31 -0.6745 -0.4724 302250.0 -204853.84 -1.12435605406222 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I12 mock treatment 418100.0 51300.0 0.29 529600.0 135000.0 0.79 0.9419 0.8931 543470.0 36366.16 0.199598465710944 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I13 mock treatment 287270.0 -79600.0 -0.45 450640.0 56500.0 0.33 0.004 0.0055 579800.0 72696.16 0.398998464481191 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I14 mock treatment 229690.0 -137000.0 -0.77 510980.0 117000.0 0.68 0.3622 0.3065 591810.0 84706.16 0.464916273047959 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I15 mock treatment 377980.0 11100.0 0.06 520720.0 127000.0 0.73 0.4101 0.4089 421600.0 -85503.84 -0.469294401069403 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I16 mock treatment 484870.0 118000.0 0.66 472860.0 78700.0 0.46 0.8812 0.9504 557350.0 50246.16 0.275779913080364 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I17 mock treatment 257670.0 -109000.0 -0.61 428910.0 34700.0 0.2 -0.3771 -0.4855 521920.0 14816.16 0.0813196335199499 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I18 mock treatment 422680.0 55800.0 0.31 388240.0 -5950.0 -0.03 -0.0852 -0.1718 493230.0 -13873.84 -0.0761476377357173 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I19 mock treatment 308500.0 -58300.0 -0.33 367480.0 -26700.0 -0.15 0.1154 0.1477 511300.0 4196.15999999997 0.0230309468439239 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I20 mock treatment 307150.0 -59700.0 -0.34 453080.0 58900.0 0.34 -0.4208 -0.4912 380800.0 -126303.84 -0.693228338581819 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I21 mock treatment 268350.0 -98500.0 -0.55 383110.0 -11100.0 -0.06 -0.2794 -0.3132 602030.0 94926.16 0.521009528964059 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I22 mock treatment 474030.0 107000.0 0.6 329920.0 -64300.0 -0.37 0.0249 0.0341 475050.0 -32053.84 -0.175929965774338 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I23 mock treatment 266130.0 -101000.0 -0.57 324080.0 -70100.0 -0.41 -0.5347 -0.4326 367220.0 -139883.84 -0.767763212881295 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base I24 mock treatment 258720.0 -108000.0 -0.61 405890.0 11700.0 0.07 0.2371 0.248 579750.0 72646.16 0.398724035636201 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J01 mock treatment 407570.0 40700.0 0.23 457020.0 62800.0 0.36 0.3253 0.5504 564220.0 57116.16 0.313486436382087 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J02 mock treatment 434560.0 67700.0 0.38 293610.0 -101000.0 -0.58 -0.0215 -0.0223 605830.0 98726.16 0.541866121183353 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J03 mock treatment 483380.0 117000.0 0.66 329640.0 -64500.0 -0.37 -0.0539 -0.0413 339170.0 -167933.84 -0.921717794921081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J04 mock treatment 238050.0 -129000.0 -0.73 123210.0 -271000.0 -1.57 -2.038 -0.8251 186080.0 -321023.84 -1.76196403251363 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J05 mock treatment 221790.0 -145000.0 -0.82 347910.0 -46300.0 -0.27 -1.4403 -0.8519 251770.0 -255333.84 -1.40141941596484 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J06 mock treatment 262500.0 -104000.0 -0.59 219950.0 -174000.0 -1.01 -1.5093 -0.9597 337370.0 -169733.84 -0.931597233340747 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J07 mock treatment 466510.0 99700.0 0.56 186400.0 -208000.0 -1.21 -1.3473 -0.6759 278670.0 -228433.84 -1.25377669735984 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J08 mock treatment 519880.0 153000.0 0.86 501850.0 108000.0 0.62 0.6072 0.5537 506080.0 -1023.84000000003 -0.00561942457310583 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J09 mock treatment 286840.0 -80000.0 -0.45 366330.0 -27900.0 -0.16 -1.4279 -0.8583 284030.0 -223073.84 -1.22435792517683 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J10 mock treatment 374580.0 7740.0 0.04 423710.0 29500.0 0.17 -0.4659 -0.5363 435800.0 -71303.84 -0.391356609092042 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J11 mock treatment 350660.0 -16200.0 -0.09 390290.0 -3900.0 -0.02 -0.2068 -0.2055 605950.0 98846.16 0.542524750411331 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J12 mock treatment 392960.0 26100.0 0.15 540230.0 146000.0 0.85 0.0364 0.0336 411220.0 -95883.84 -0.526265829289474 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J13 mock treatment 453530.0 86700.0 0.49 436820.0 42600.0 0.25 1.059 0.9288 605850.0 98746.16 0.541975892721349 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J14 mock treatment 381200.0 14400.0 0.08 322650.0 -71500.0 -0.41 0.3391 0.3931 569600.0 62496.16 0.343014980103087 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J15 mock treatment 355430.0 -11400.0 -0.06 458610.0 64400.0 0.37 0.5233 0.811 578020.0 70916.16 0.389228797599522 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J16 mock treatment 479360.0 113000.0 0.63 455680.0 61500.0 0.36 -0.1248 -0.1031 341370.0 -165733.84 -0.90964292574149 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J17 mock treatment 397920.0 31100.0 0.17 278340.0 -116000.0 -0.67 -0.4145 -0.5201 436520.0 -70583.84 -0.387404833724176 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J18 mock treatment 381120.0 14300.0 0.08 512320.0 118000.0 0.69 0.479 0.6249 485330.0 -21773.84 -0.119507395244249 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J19 mock treatment 364420.0 -2420.0 -0.01 440690.0 46500.0 0.27 0.2286 0.4974 569710.0 62606.16 0.343618723562067 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J20 mock treatment 409600.0 42800.0 0.24 426720.0 32500.0 0.19 0.0342 0.0809 492640.0 -14463.84 -0.0793858981066077 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J21 mock treatment 386600.0 19800.0 0.11 391870.0 -2320.0 -0.01 -0.0716 -0.1201 413030.0 -94073.84 -0.51633150510081 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J22 mock treatment 339870.0 -27000.0 -0.15 382160.0 -12000.0 -0.07 -0.1381 -0.6953 489240.0 -17863.84 -0.0980470595659757 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J23 mock treatment 357280.0 -9560.0 -0.05 347420.0 -46800.0 -0.27 0.1126 0.2205 580680.0 73576.16 0.403828412153028 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base J24 mock treatment 309360.0 -57500.0 -0.32 273300.0 -121000.0 -0.7 -0.3504 -0.3874 589650.0 82546.16 0.453060946944361 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K01 mock treatment 345310.0 -21500.0 -0.12 497800.0 104000.0 0.6 -0.8634 -0.5145 316050.0 -191053.84 -1.04861369284478 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K02 mock treatment 303360.0 -63500.0 -0.36 500570.0 106000.0 0.62 0.3326 0.395 588380.0 81276.16 0.446090454281597 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K03 mock treatment 252230.0 -115000.0 -0.65 259480.0 -135000.0 -0.78 -1.3864 -0.9885 408270.0 -98833.84 -0.542457131143925 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K04 mock treatment 322430.0 -44400.0 -0.25 148060.0 -246000.0 -1.43 -0.0398 -0.0216 631360.0 124256.16 0.681989489435608 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K05 mock treatment 418240.0 51400.0 0.29 434080.0 39900.0 0.23 0.4811 0.638 472870.0 -34233.84 -0.187895063415933 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K06 mock treatment 328560.0 -38300.0 -0.22 289940.0 -104000.0 -0.6 -0.4645 -0.4534 599560.0 92456.16 0.507452744021519 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K07 mock treatment 310990.0 -55900.0 -0.31 512830.0 119000.0 0.69 -0.5086 -0.3944 335040.0 -172063.84 -0.944385617517314 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K08 mock treatment 415300.0 48500.0 0.27 378190.0 -16000.0 -0.09 0.6147 0.7622 619370.0 112266.16 0.616181452406836 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K09 mock treatment 348830.0 -18000.0 -0.1 449650.0 55500.0 0.32 0.776 0.7742 620090.0 112986.16 0.620133227774702 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K10 mock treatment 351900.0 -14900.0 -0.08 499130.0 105000.0 0.61 0.7844 0.8166 602520.0 95416.16 0.523698931644968 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K11 mock treatment 383810.0 17000.0 0.1 383880.0 -10300.0 -0.06 -0.7508 -0.6844 354900.0 -152203.84 -0.835382480287005 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K12 mock treatment 360660.0 -6180.0 -0.03 454670.0 60500.0 0.35 0.3087 0.4553 465180.0 -41923.84 -0.230102219775504 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K13 mock treatment 476700.0 110000.0 0.62 490340.0 96200.0 0.56 0.8601 0.7641 472610.0 -34493.84 -0.189322093409885 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K14 mock treatment 468900.0 102000.0 0.57 531910.0 138000.0 0.8 1.5105 0.9426 593810.0 86706.16 0.475893426847587 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K15 mock treatment 349220.0 -17600.0 -0.1 469070.0 74900.0 0.43 0.6045 0.7933 589280.0 82176.16 0.451030173491429 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K16 mock treatment 227740.0 -139000.0 -0.78 484000.0 89800.0 0.52 -0.1335 -0.1092 607280.0 100176.16 0.549824557688084 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K17 mock treatment 497770.0 131000.0 0.74 490950.0 96800.0 0.56 0.6508 0.697 492440.0 -14663.84 -0.0804836134865705 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K18 mock treatment 478320.0 111000.0 0.63 550790.0 157000.0 0.91 0.9024 0.7405 593400.0 86296.16 0.473643110318663 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K19 mock treatment 442190.0 75300.0 0.42 527130.0 133000.0 0.77 1.1698 0.902 676120.0 169016.16 0.927658191471288 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K20 mock treatment 466740.0 99900.0 0.56 465440.0 71300.0 0.41 1.1831 0.9812 634440.0 127336.16 0.698894306287035 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K21 mock treatment 314570.0 -52300.0 -0.29 455870.0 61700.0 0.36 0.3044 0.4152 610560.0 103456.16 0.567827089919474 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K22 mock treatment 353150.0 -13700.0 -0.08 346110.0 -48100.0 -0.28 -0.4924 -0.6475 520000.0 12896.16 0.0707815658723068 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K23 mock treatment 423140.0 56300.0 0.32 385300.0 -8890.0 -0.05 -0.5787 -0.4436 278820.0 -228283.84 -1.25295341082486 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base K24 mock treatment 430030.0 63200.0 0.36 417680.0 23500.0 0.14 0.7577 0.921 611910.0 104806.16 0.575236668734223 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L01 mock treatment 337030.0 -29800.0 -0.17 475700.0 81500.0 0.47 -0.5331 -0.2925 194150.0 -312953.84 -1.71767121693213 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L02 mock treatment 412000.0 45200.0 0.25 474610.0 80400.0 0.47 0.4651 0.6463 585760.0 78656.16 0.431710382804084 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L03 mock treatment 132700.0 -234000.0 -1.32 294240.0 -99900.0 -0.58 -1.2324 -0.8203 435900.0 -71203.84 -0.390807751402061 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L04 mock treatment 446830.0 80000.0 0.45 494370.0 100000.0 0.58 0.0749 0.0765 449300.0 -57803.84 -0.317260820944552 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L05 mock treatment 278150.0 -88700.0 -0.5 517340.0 123000.0 0.71 -0.2017 -0.2068 448800.0 -58303.84 -0.320005109394459 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L06 mock treatment 289410.0 -77400.0 -0.44 287790.0 -106000.0 -0.62 -0.8526 -0.9069 406880.0 -100223.84 -0.550086253034667 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L07 mock treatment 324810.0 -42000.0 -0.24 261550.0 -133000.0 -0.77 -0.4959 -0.4796 592020.0 84916.16 0.46606887419692 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L08 mock treatment 416600.0 49800.0 0.28 257280.0 -137000.0 -0.79 -0.7733 -0.6638 369310.0 -137793.84 -0.756292087160684 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L09 mock treatment 480390.0 114000.0 0.64 516160.0 122000.0 0.71 1.1414 0.9657 621130.0 114026.16 0.625841347750509 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L10 mock treatment 530610.0 164000.0 0.92 432360.0 38200.0 0.22 0.7791 0.7782 561820.0 54716.16 0.300313851822533 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L11 mock treatment 524280.0 157000.0 0.89 485940.0 91800.0 0.53 0.5274 0.3597 344160.0 -162943.84 -0.894329796191009 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L12 mock treatment 397230.0 30400.0 0.17 459280.0 65100.0 0.38 -0.0185 -0.0224 379080.0 -128023.84 -0.7026686908495 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L13 mock treatment 412910.0 46100.0 0.26 375000.0 -19200.0 -0.11 0.2719 0.5853 512160.0 5056.15999999997 0.027751122977764 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L14 mock treatment 418750.0 51900.0 0.29 383200.0 -11000.0 -0.06 0.3116 0.4849 479220.0 -27883.84 -0.153042600102113 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L15 mock treatment 438770.0 71900.0 0.4 527360.0 133000.0 0.77 0.5621 0.5865 553250.0 46146.16 0.253276747791126 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L16 mock treatment 362140.0 -4700.0 -0.03 514560.0 120000.0 0.7 0.6377 0.7485 531730.0 24626.16 0.135162572907126 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L17 mock treatment 500840.0 134000.0 0.75 512080.0 118000.0 0.68 0.9202 0.8098 490030.0 -17073.84 -0.0937110838151225 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L18 mock treatment 412840.0 46000.0 0.26 373410.0 -20800.0 -0.12 0.1732 0.5355 521180.0 14076.16 0.0772580866140874 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L19 mock treatment 417950.0 51100.0 0.29 461820.0 67600.0 0.39 0.7601 0.9105 625850.0 118746.16 0.651747430717632 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L20 mock treatment 458880.0 92000.0 0.52 328100.0 -66100.0 -0.38 0.4007 0.4982 555360.0 48256.16 0.264857645049734 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L21 mock treatment 314880.0 -52000.0 -0.29 346260.0 -47900.0 -0.28 -0.0208 -0.0373 566080.0 58976.16 0.323695189415742 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L22 mock treatment 293850.0 -73000.0 -0.41 289350.0 -105000.0 -0.61 -0.0773 -0.0786 616320.0 109216.16 0.599441292862403 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L23 mock treatment 240930.0 -126000.0 -0.71 391680.0 -2510.0 -0.01 -0.5113 -0.6466 515790.0 8686.15999999997 0.0476746571240893 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base L24 mock treatment 420390.0 53500.0 0.3 332970.0 -61200.0 -0.36 0.2251 0.3837 555210.0 48106.16 0.264034358514762 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M01 mock treatment 393440.0 26600.0 0.15 443730.0 49500.0 0.29 -0.1639 -0.2577 448170.0 -58933.84 -0.323462912841342 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M02 mock treatment 482160.0 115000.0 0.65 413380.0 19200.0 0.11 0.2168 0.3051 494560.0 -12543.84 -0.0688478304589645 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M03 mock treatment 340280.0 -26600.0 -0.15 438360.0 44200.0 0.26 0.2564 0.413 603810.0 96706.16 0.530779195845729 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M04 mock treatment 380050.0 13200.0 0.07 474180.0 80000.0 0.46 0.2466 0.3292 578080.0 70976.16 0.389558112213511 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M05 mock treatment 381070.0 14200.0 0.08 356510.0 -37700.0 -0.22 0.315 0.4617 621020.0 113916.16 0.62523760429153 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M06 mock treatment 397710.0 30900.0 0.17 503200.0 109000.0 0.63 0.8018 0.9266 583430.0 76326.16 0.418921998627517 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M07 mock treatment 285820.0 -81000.0 -0.46 440980.0 46800.0 0.27 -0.3156 -0.4939 445310.0 -61793.84 -0.33916024277481 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M08 mock treatment 410640.0 43800.0 0.25 413550.0 19400.0 0.11 0.3826 0.7698 583010.0 75906.16 0.416616796329595 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M09 mock treatment 421190.0 54300.0 0.31 516450.0 122000.0 0.71 0.841 0.8882 603800.0 96696.16 0.53072431007673 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M10 mock treatment 434620.0 67800.0 0.38 417020.0 22800.0 0.13 0.879 0.9058 611520.0 104416.16 0.573096123743295 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M11 mock treatment 386340.0 19500.0 0.11 437120.0 42900.0 0.25 0.2197 0.301 601440.0 94336.16 0.517771268593169 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M12 mock treatment 443680.0 76800.0 0.43 432550.0 38400.0 0.22 0.6892 0.8807 616540.0 109436.16 0.600648779780362 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M13 mock treatment 462140.0 95300.0 0.54 510110.0 116000.0 0.67 0.356 0.322 384640.0 -122463.84 -0.672152203286533 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M14 mock treatment 387580.0 20700.0 0.12 497560.0 103000.0 0.6 0.5876 0.8465 541250.0 34146.16 0.187413824993357 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M15 mock treatment 339620.0 -27200.0 -0.15 449830.0 55600.0 0.32 0.1772 0.3846 557440.0 50336.16 0.276273885001348 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M16 mock treatment 324570.0 -42300.0 -0.24 408710.0 14500.0 0.08 0.0737 0.1824 504560.0 -2543.84000000003 -0.0139620614608233 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M17 mock treatment 447710.0 80900.0 0.46 310080.0 -84100.0 -0.49 0.2496 0.3225 541250.0 34146.16 0.187413824993357 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M18 mock treatment 499490.0 133000.0 0.75 496350.0 102000.0 0.59 1.0569 0.9572 564380.0 57276.16 0.314364608686058 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M19 mock treatment 450920.0 84100.0 0.47 477450.0 83300.0 0.48 1.0314 0.9461 652360.0 145256.16 0.797249604331704 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M20 mock treatment 490320.0 123000.0 0.7 405380.0 11200.0 0.06 0.8386 0.8798 587970.0 80866.16 0.443840137752673 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M21 mock treatment 393370.0 26500.0 0.15 379210.0 -15000.0 -0.09 0.3495 0.6949 583550.0 76446.16 0.419580627855494 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M22 mock treatment 366660.0 -183.0 0.0 381060.0 -13100.0 -0.08 0.1022 0.2869 569500.0 62396.16 0.342466122413106 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M23 mock treatment 411210.0 44400.0 0.25 254920.0 -139000.0 -0.81 -0.1211 -0.1295 578680.0 71576.16 0.3928512583534 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base M24 mock treatment 427300.0 60500.0 0.34 307330.0 -86900.0 -0.5 -0.1489 -0.2419 492210.0 -14893.84 -0.0817459861735277 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N01 mock treatment 394190.0 27300.0 0.15 383690.0 -10500.0 -0.06 -0.4571 -0.5233 353770.0 -153333.84 -0.841584572183795 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N02 mock treatment 448590.0 81700.0 0.46 350330.0 -43900.0 -0.25 -0.0477 -0.0841 478810.0 -28293.84 -0.155292916631037 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N03 mock treatment 288510.0 -78300.0 -0.44 485210.0 91000.0 0.53 -0.0983 -0.0957 576210.0 69106.16 0.379294473410859 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N04 mock treatment 362310.0 -4530.0 -0.03 446290.0 52100.0 0.3 -0.2952 -0.4022 462400.0 -44703.84 -0.245360463556987 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N05 mock treatment 414210.0 47400.0 0.27 308320.0 -85900.0 -0.5 -0.5179 -0.6309 411070.0 -96033.84 -0.527089115824446 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N06 mock treatment 420160.0 53300.0 0.3 311230.0 -83000.0 -0.48 -0.2188 -0.3185 527860.0 20756.16 0.113921780304846 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N07 mock treatment 193440.0 -173000.0 -0.98 361440.0 -32700.0 -0.19 -0.457 -0.4498 544050.0 36946.16 0.202781840312836 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N08 mock treatment 518980.0 152000.0 0.86 285200.0 -109000.0 -0.63 0.3956 0.3352 599290.0 92186.16 0.505970828258569 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N09 mock treatment 419380.0 52500.0 0.3 471550.0 77400.0 0.45 -0.0528 -0.0328 250090.0 -257013.84 -1.41064022515652 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N10 mock treatment 512290.0 145000.0 0.82 325800.0 -68400.0 -0.4 0.6103 0.5634 600910.0 93806.16 0.514862322836268 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N11 mock treatment 438240.0 71400.0 0.4 466250.0 72100.0 0.42 0.6798 0.9777 551130.0 44026.16 0.24164096476352 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N12 mock treatment 421030.0 54200.0 0.31 461860.0 67700.0 0.39 0.6303 0.9702 574910.0 67806.16 0.3721593234411 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N13 mock treatment 339080.0 -27800.0 -0.16 438020.0 43800.0 0.25 0.4016 0.6772 586590.0 79486.16 0.436265901630929 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N14 mock treatment 407800.0 41000.0 0.23 428000.0 33800.0 0.2 0.1993 0.3413 568820.0 61716.16 0.338733890121232 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N15 mock treatment 393920.0 27100.0 0.15 427680.0 33500.0 0.19 -0.2481 -0.3519 393670.0 -113433.84 -0.622590353881212 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N16 mock treatment 404000.0 37200.0 0.21 347380.0 -46800.0 -0.27 0.322 0.5113 549250.0 42146.16 0.23132244019187 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N17 mock treatment 440020.0 73200.0 0.41 385440.0 -8750.0 -0.05 0.3081 0.5162 580480.0 73376.16 0.402730696773065 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N18 mock treatment 345280.0 -21600.0 -0.12 525190.0 131000.0 0.76 0.2797 0.3243 549640.0 42536.16 0.233462985182797 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N19 mock treatment 362760.0 -4080.0 -0.02 454630.0 60400.0 0.35 0.6526 0.829 613640.0 106536.16 0.584731906770901 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N20 mock treatment 398150.0 31300.0 0.18 325760.0 -68400.0 -0.4 0.0794 0.1427 570240.0 63136.16 0.346527669318968 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N21 mock treatment 339690.0 -27200.0 -0.15 382160.0 -12000.0 -0.07 0.1694 0.3649 580490.0 73386.16 0.402785582542063 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N22 mock treatment 388660.0 21800.0 0.12 502530.0 108000.0 0.63 0.8088 0.9004 605000.0 97896.16 0.537310602356507 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N23 mock treatment 409920.0 43100.0 0.24 361230.0 -33000.0 -0.19 -0.1997 -0.4445 457010.0 -50093.84 -0.274943893046985 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base N24 mock treatment 369190.0 2350.0 0.01 391800.0 -2390.0 -0.01 -0.1285 -0.6519 474080.0 -33023.84 -0.181253885367158 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O01 mock treatment 433810.0 67000.0 0.38 421300.0 27100.0 0.16 0.6405 0.9509 586680.0 79576.16 0.436759873551913 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O02 mock treatment 306130.0 -60700.0 -0.34 506040.0 112000.0 0.65 0.6863 0.6483 588330.0 81226.16 0.445816025436606 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O03 mock treatment 419590.0 52700.0 0.3 478360.0 84200.0 0.49 0.1712 0.2512 492500.0 -14603.84 -0.0801542988725816 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O04 mock treatment 496120.0 129000.0 0.73 403890.0 9700.0 0.06 0.426 0.5805 520960.0 13856.16 0.0760505996961283 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O05 mock treatment 291560.0 -75300.0 -0.42 477930.0 83700.0 0.49 0.3673 0.458 572860.0 65756.16 0.360907740796481 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O06 mock treatment 337450.0 -29400.0 -0.17 318090.0 -76100.0 -0.44 0.0318 0.046 591040.0 83936.16 0.460690068835102 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O07 mock treatment 319220.0 -47600.0 -0.27 347620.0 -46600.0 -0.27 -0.5812 -0.6569 536000.0 28896.16 0.158598796269333 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O08 mock treatment 532320.0 165000.0 0.93 442080.0 47900.0 0.28 0.4708 0.4433 532130.0 25026.16 0.137358003667052 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O09 mock treatment 507050.0 140000.0 0.79 429700.0 35500.0 0.21 0.9137 0.9084 581320.0 74216.16 0.407341101368909 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O10 mock treatment 353120.0 -13700.0 -0.08 448820.0 54600.0 0.32 0.2429 0.5847 505120.0 -1983.84000000003 -0.0108884583969274 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O11 mock treatment 447760.0 80900.0 0.46 426150.0 32000.0 0.19 0.2033 0.3767 466580.0 -40523.84 -0.222418212115764 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O12 mock treatment 460090.0 93200.0 0.52 528760.0 135000.0 0.78 0.4847 0.4978 487240.0 -19863.84 -0.109024213365604 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O13 mock treatment 364870.0 -1970.0 -0.01 503280.0 109000.0 0.63 0.2574 0.3928 517040.0 9936.15999999997 0.054535378248857 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O14 mock treatment 398400.0 31600.0 0.18 508830.0 115000.0 0.66 0.5383 0.76 524900.0 17796.16 0.097675592681396 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O15 mock treatment 457440.0 90600.0 0.51 406340.0 12200.0 0.07 0.3577 0.5202 461960.0 -45143.84 -0.247775437392905 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O16 mock treatment 408640.0 41800.0 0.24 398670.0 4480.0 0.03 0.0326 0.0943 462240.0 -44863.84 -0.246238635860957 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O17 mock treatment 391930.0 25100.0 0.14 379790.0 -14400.0 -0.08 -0.0138 -0.0688 512100.0 4996.15999999997 0.0274218083637752 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O18 mock treatment 374600.0 7760.0 0.04 480870.0 86700.0 0.5 0.2005 0.2923 552210.0 45106.16 0.24756862781532 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O19 mock treatment 372840.0 6000.0 0.03 413760.0 19600.0 0.11 0.2952 0.4469 474120.0 -32983.84 -0.181034342291165 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O20 mock treatment 370750.0 3910.0 0.02 415540.0 21400.0 0.12 -0.107 -0.2871 443210.0 -63893.84 -0.35068625426442 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O21 mock treatment 350720.0 -16100.0 -0.09 456770.0 62600.0 0.36 0.5509 0.7237 542890.0 35786.16 0.196415091109052 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O22 mock treatment 409400.0 42600.0 0.24 417510.0 23300.0 0.14 0.3549 0.6044 597080.0 89976.16 0.493841073309979 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O23 mock treatment 381950.0 15100.0 0.09 393080.0 -1110.0 -0.01 0.6334 0.7352 593380.0 86276.16 0.473533338780667 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base O24 mock treatment 291280.0 -75600.0 -0.43 292550.0 -102000.0 -0.59 -0.1052 -0.1139 584570.0 77466.16 0.425178976293305 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P01 mock treatment 417720.0 50900.0 0.29 296490.0 -97700.0 -0.57 -0.2923 -0.3933 438010.0 -69093.84 -0.379226854143453 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P02 mock treatment 233670.0 -133000.0 -0.75 424240.0 30100.0 0.17 -0.8241 -0.6785 337960.0 -169143.84 -0.928358972969856 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P03 mock treatment 206250.0 -161000.0 -0.9 282110.0 -112000.0 -0.65 -0.7832 -0.6991 490110.0 -16993.84 -0.0932719976631374 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P04 mock treatment 246720.0 -120000.0 -0.68 256530.0 -138000.0 -0.8 -0.6014 -0.5626 545370.0 38266.16 0.210026761820591 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P05 mock treatment 291920.0 -74900.0 -0.42 321190.0 -73000.0 -0.42 -0.3503 -0.4832 469080.0 -38023.84 -0.208696769866228 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P06 mock treatment 252020.0 -115000.0 -0.65 475000.0 80800.0 0.47 -0.4496 -0.4222 378760.0 -128343.84 -0.70442503545744 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P07 mock treatment 161520.0 -205000.0 -1.16 264480.0 -130000.0 -0.75 -1.1247 -0.7689 530570.0 23466.16 0.128795823703342 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P08 mock treatment 406720.0 39900.0 0.22 303520.0 -90700.0 -0.53 -0.4225 -0.5031 519430.0 12326.16 0.0676530770394127 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P09 mock treatment 257760.0 -109000.0 -0.61 174960.0 -219000.0 -1.27 -1.0707 -0.7351 444000.0 -63103.84 -0.346350278513567 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P10 mock treatment 395050.0 28200.0 0.16 421510.0 27300.0 0.16 0.0995 0.3462 475840.0 -31263.84 -0.171593990023485 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P11 mock treatment 441850.0 75000.0 0.42 255210.0 -139000.0 -0.81 -0.5213 -0.4744 498990.0 -8113.84000000003 -0.044533434792788 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P12 mock treatment 397700.0 30900.0 0.17 431220.0 37000.0 0.21 0.1171 0.3845 484360.0 -22743.84 -0.124831314837069 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P13 mock treatment 273050.0 -93800.0 -0.53 443590.0 49400.0 0.29 -0.1111 -0.1619 466110.0 -40993.84 -0.224997843258676 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P14 mock treatment 406020.0 39200.0 0.22 304810.0 -89400.0 -0.52 -0.4429 -0.6289 463380.0 -43723.84 -0.239981658195169 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P15 mock treatment 267010.0 -99800.0 -0.56 402770.0 8580.0 0.05 -0.7534 -0.8356 416710.0 -90393.84 -0.496133542109494 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P16 mock treatment 274350.0 -92500.0 -0.52 403700.0 9510.0 0.06 -0.9234 -0.7908 428700.0 -78403.84 -0.430325505080723 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P17 mock treatment 256970.0 -110000.0 -0.62 408360.0 14200.0 0.08 -0.4474 -0.6496 493010.0 -14093.84 -0.0773551246536764 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P18 mock treatment 413250.0 46400.0 0.26 386020.0 -8170.0 -0.05 -0.4058 -0.4967 379360.0 -127743.84 -0.701131889317552 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P19 mock treatment 284680.0 -82200.0 -0.46 305990.0 -88200.0 -0.51 -1.2855 -0.9684 375490.0 -131613.84 -0.722372681919832 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P20 mock treatment 369550.0 2710.0 0.02 300400.0 -93800.0 -0.54 -0.761 -0.8529 427110.0 -79993.84 -0.439052342351427 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P21 mock treatment 302090.0 -64800.0 -0.36 310030.0 -84200.0 -0.49 -1.0704 -0.9029 448010.0 -59093.84 -0.324341085145312 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P22 mock treatment 394190.0 27300.0 0.15 316800.0 -77400.0 -0.45 -0.6266 -0.7312 391010.0 -116093.84 -0.637189968434717 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P23 mock treatment 303310.0 -63500.0 -0.36 412510.0 18300.0 0.11 -0.8386 -0.7354 426240.0 -80863.84 -0.443827404254265 1001.0066 CellTiterGlo(1001.0066) MODYPatientCellProfiling 1001.0066.Base P24 mock treatment 314090.0 -52800.0 -0.3 289220.0 -105000.0 -0.61 -1.1197 -0.79 280910.0 -226193.84 -1.24148228510425