# go

id: GO:0034541
name: dimethylarsinite methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH." [UM-BBD_reactionID:r0806]


id: GO:0034542
name: trimethylarsine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O." [UM-BBD_reactionID:r0807]


id: GO:0034543
name: 5-aminosalicylate dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate." [UM-BBD_reactionID:r0809]


id: GO:0034544
name: trans-ACOHDA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3." [UM-BBD_reactionID:r0810]


id: GO:0034545
name: fumarylpyruvate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+." [UM-BBD_reactionID:r0811]


id: GO:0034546
name: 2,4-dichloroaniline reductive dehalogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl." [UM-BBD_reactionID:r0819]


id: GO:0034547
name: N-cyclopropylmelamine deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3." [UM-BBD_reactionID:r0825]


id: GO:0034548
name: N-cyclopropylammeline deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3." [UM-BBD_reactionID:r0826]


id: GO:0034549
name: N-cyclopropylammelide alkylamino hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid." [UM-BBD_reactionID:r0827]


id: GO:0034550
name: dimethylarsinate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O." [UM-BBD_reactionID:r0838]


id: GO:0034551
name: mitochondrial respiratory chain complex III assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane." [GOC:dgf, GOC:mcc]


id: GO:0034552
name: respiratory chain complex II assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II." [GOC:dgf]


id: GO:0034553
name: mitochondrial respiratory chain complex II assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane." [GOC:dgf]


id: GO:0034554
name: 3,3',5-tribromobisphenol A reductive dehalogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr." [UM-BBD_reactionID:r0842]


id: GO:0034555
name: 3,3'-dibromobisphenol A reductive dehalogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr." [UM-BBD_reactionID:r0844]


id: GO:0034556
name: nitrobenzoate nitroreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+." [UM-BBD_reactionID:r0849]


id: GO:0034557
name: 2-hydroxylaminobenzoate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O." [MetaCyc:RXN-8848]


id: GO:0034558
name: technetium (VII) reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-." [UM-BBD_reactionID:r0859]


id: GO:0034559
name: bisphenol A hydroxylase B activity
namespace: molecular_function
def:
  "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0860]


id: GO:0034560
name: bisphenol A hydroxylase A activity
namespace: molecular_function
def:
  "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0861]


id: GO:0034561
name: 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O." [UM-BBD_reactionID:r0862]


id: GO:0034562
name: 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O." [UM-BBD_reactionID:r0864]


id: GO:0034563
name: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-." [UM-BBD_reactionID:r0867]


id: GO:0034564
name: 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-." [UM-BBD_reactionID:r0866]


id: GO:0034565
name: 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol." [UM-BBD_reactionID:r0872]


id: GO:0034568
name: isoproturon dimethylaminedehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-." [UM-BBD_reactionID:r0892]


id: GO:0034569
name: monodemethylisoproturon dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-." [UM-BBD_reactionID:r0893]


id: GO:0034570
name: hydroxymonomethylisoproturon dimethylaminedehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0894]


id: GO:0034571
name: 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid." [UM-BBD_reactionID:r0895]


id: GO:0034572
name: monodemethylisoproturon dimethylaminedehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-." [UM-BBD_reactionID:r0897]


id: GO:0034573
name: didemethylisoproturon amidohydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline." [UM-BBD_reactionID:r0898]


id: GO:0034574
name: didemethylisoproturon dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0899]


id: GO:0034575
name: 4-isopropylaniline dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-." [UM-BBD_reactionID:r0901]


id: GO:0034576
name: N-isopropylacetanilide amidohydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate." [UM-BBD_reactionID:r0913]


id: GO:0034577
name: N-isopropylacetaniline monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone." [UM-BBD_reactionID:r0914]


id: GO:0034579
name: (1-methylpentyl)succinate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate." [UM-BBD_reactionID:r0920]


id: GO:0034580
name: 4-methyloctanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0924]


id: GO:0034581
name: 4-methyloct-2-enoyl-CoA hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA." [UM-BBD_reactionID:r0925]


id: GO:0034582
name: 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0926]


id: GO:0034583
name: 21U-RNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv]


id: GO:0034584
name: piRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv]


id: GO:0034585
name: 21U-RNA metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv]


id: GO:0034586
name: 21U-RNA catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv]


id: GO:0034587
name: piRNA metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv]


id: GO:0034588
name: piRNA catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv]


id: GO:0034589
name: hydroxyproline transport
namespace: biological_process
def:
  "The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah, PMID:14502423]


id: GO:0034590
name: L-hydroxyproline transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of L-hydroxyproline from one side of a membrane to the other." [GOC:mah, PMID:14502423]


id: GO:0034593
name: phosphatidylinositol bisphosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate." [GOC:mah]


id: GO:0034594
name: phosphatidylinositol trisphosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate." [GOC:mah]


id: GO:0034597
name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate." [GOC:mah]


id: GO:0034598
name: phosphothreonine lyase activity
namespace: molecular_function
def:
  "Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product." [PMID:17303758, PMID:18084305]


id: GO:0034599
name: cellular response to oxidative stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah]


id: GO:0034601
name: oxoglutarate dehydrogenase [NAD(P)+] activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H." [GOC:mah]


id: GO:0034604
name: pyruvate dehydrogenase (NAD+) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH." [GOC:mah, ISBN:0201090910]


id: GO:0034605
name: cellular response to heat
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:mah]


id: GO:0034606
name: response to hermaphrodite contact
namespace: biological_process
def:
  "The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." [PMID:18050467, WB_REF:WBPaper00002109]


id: GO:0034607
name: turning behavior involved in mating
namespace: biological_process
def:
  "The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [PMID:18050467, WB_REF:WBPaper00002109]


id: GO:0034608
name: vulval location
namespace: biological_process
def:
  "Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." [PMID:18050467]


id: GO:0034609
name: spicule insertion
namespace: biological_process
def:
  "Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." [PMID:18050467]


id: GO:0034610
name: oligodeoxyribonucleotidase activity
namespace: molecular_function
def:
  "Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates." [GOC:mah]


id: GO:0034611
name: oligoribonucleotidase activity
namespace: molecular_function
def:
  "Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates." [GOC:mah]


id: GO:0034612
name: response to tumor necrosis factor
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus." [GOC:mah]


id: GO:0034613
name: cellular protein localization
namespace: biological_process
def:
  "Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah]


id: GO:0034614
name: cellular response to reactive oxygen species
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:mah]


id: GO:0034615
name: GCH1 complex
namespace: cellular_component
def:
  "A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive." [PMID:16696853]


id: GO:0034616
name: response to laminar fluid shear stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls." [GOC:ecd]


id: GO:0034617
name: tetrahydrobiopterin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions." [CHEBI:15372, GOC:BHF, GOC:mah, GOC:rl]


id: GO:0034618
name: arginine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid." [CHEBI:29016, GOC:BHF, GOC:rl]


id: GO:0034620
name: cellular response to unfolded protein
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." [GOC:mah]


id: GO:0034622
name: cellular macromolecular complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level." [GOC:mah]


id: GO:0034624
name: DNA recombinase assembly involved in gene conversion at mating-type locus
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another." [GOC:mah]


id: GO:0034626
name: fatty acid elongation, polyunsaturated fatty acid
namespace: biological_process
def:
  "Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced." [GOC:mah]


id: GO:0034627
name: 'de novo' NAD biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:imk, PMID:17161604]


id: GO:0034628
name: 'de novo' NAD biosynthetic process from aspartate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:imk]


id: GO:0034629
name: cellular protein complex localization
namespace: biological_process
def:
  "A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell." [GOC:mah]


id: GO:0034630
name: RITS complex localization
namespace: biological_process
def:
  "Any process in which a RITS complex is transported to, or maintained in, a specific location." [GOC:mah]


id: GO:0034631
name: microtubule anchoring at spindle pole body
namespace: biological_process
def:
  "Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end." [GOC:mah, PMID:17486116]


id: GO:0034632
name: retinol transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of retinol into, out of or within a cell, or between cells. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah, GOC:vk]


id: GO:0034633
name: retinol transport
namespace: biological_process
def:
  "The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah, GOC:vk]


id: GO:0034634
name: glutathione transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of glutathione, the tripeptide glutamylcysteinylglycine, across a membrane into, out of or within a cell, or between cells." [GOC:mah]


id: GO:0034635
name: glutathione transport
namespace: biological_process
def:
  "The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034636
name: strand invasion involved in gene conversion at mating-type locus
namespace: biological_process
def:
  "The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA at the mating-type locus. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This process occurs as part of gene conversion at the mating-type locus." [GOC:mah]


id: GO:0034637
name: cellular carbohydrate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells." [GOC:mah]


id: GO:0034638
name: phosphatidylcholine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:jp]


id: GO:0034639
name: L-amino acid efflux transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane." [GOC:mah]


id: GO:0034640
name: establishment of mitochondrion localization by microtubule attachment
namespace: biological_process
def:
  "The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization." [GOC:mah, PMID:12972644]


id: GO:0034641
name: cellular nitrogen compound metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah]


id: GO:0034642
name: mitochondrion migration along actin filament
namespace: biological_process
def:
  "The directed movement of a mitochondrion along a microfilament, mediated by motor proteins." [GOC:mah, PMID:15979253, PMID:16306220]


id: GO:0034643
name: establishment of mitochondrion localization, microtubule-mediated
namespace: biological_process
def:
  "The directed movement of the mitochondrion to a specific location, by a process involving microtubules." [GOC:mah, PMID:12972644, PMID:15979253, PMID:16306220]


id: GO:0034644
name: cellular response to UV
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:mah]


id: GO:0034645
name: cellular macromolecule biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [CHEBI:33694, GOC:mah]


id: GO:0034647
name: histone demethylase activity (H3-trimethyl-K4 specific)
namespace: molecular_function
def:
  "Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896]


id: GO:0034648
name: histone demethylase activity (H3-dimethyl-K4 specific)
namespace: molecular_function
def:
  "Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896]


id: GO:0034649
name: histone demethylase activity (H3-monomethyl-K4 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:16223729]


id: GO:0034650
name: cortisol metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties." [CHEBI:17650, GOC:BHF, GOC:mah, GOC:rl]


id: GO:0034651
name: cortisol biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties." [CHEBI:17650, GOC:BHF, GOC:mah, GOC:rl]


id: GO:0034652
name: extrachromosomal circular DNA localization involved in cell aging
namespace: biological_process
def:
  "A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging." [GOC:dph, GOC:jp, GOC:tb, PMID:18660802]


id: GO:0034653
name: retinoic acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah]


id: GO:0034654
name: nucleobase-containing compound biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah]


id: GO:0034655
name: nucleobase-containing compound catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah]


id: GO:0034656
name: nucleobase-containing small molecule catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:mah]


id: GO:0034657
name: GID complex
namespace: cellular_component
def:
  "A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p." [PMID:12686616, PMID:18508925]


id: GO:0034659
name: isopropylmalate transport
namespace: biological_process
def:
  "The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034661
name: ncRNA catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs)." [GOC:rb, PMID:18591258]


id: GO:0034662
name: CFTR-NHERF-ezrin complex
namespace: cellular_component
def:
  "A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity." [PMID:16129695, PMID:16798722, PMID:16926444]


id: GO:0034663
name: endoplasmic reticulum chaperone complex
namespace: cellular_component
def:
  "A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1." [PMID:12475965]


id: GO:0034664
name: Ig heavy chain-bound endoplasmic reticulum chaperone complex
namespace: cellular_component
def:
  "A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1." [PMID:12475965]


id: GO:0034670
name: chemotaxis to arachidonic acid
namespace: biological_process
def:
  "The directed movement of a motile cell or organism in response to the presence of arachidonic acid." [GOC:go_curators, PMID:18202452]


id: GO:0034671
namespace: biological_process
name:
  retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification

def:
  "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros." [GOC:mh]


id: GO:0034672
name: anterior/posterior pattern specification involved in pronephros development
namespace: biological_process
def:
  "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah]


id: GO:0034673
name: inhibin-betaglycan-ActRII complex
namespace: cellular_component
def:
  "A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B." [GOC:BHF, PMID:10746731]


id: GO:0034692
name: E.F.G complex
namespace: cellular_component
def:
  "A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex." [PMID:8641291]


id: GO:0034693
name: U11/U12 snRNP
namespace: cellular_component
def:
  "A ribonucleoprotein complex formed by the association of the U11 and U12 small nuclear ribonucleoproteins." [GOC:mah, PMID:15146077]


id: GO:0034694
name: response to prostaglandin
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus." [GOC:BHF, GOC:vk]


id: GO:0034695
name: response to prostaglandin E
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus." [GOC:BHF, GOC:vk]


id: GO:0034696
name: response to prostaglandin F
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus." [GOC:BHF, GOC:vk]


id: GO:0034697
name: response to prostaglandin I
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus." [GOC:BHF, GOC:vk]


id: GO:0034698
name: response to gonadotropin
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus." [GOC:BHF, GOC:vk]


id: GO:0034699
name: response to luteinizing hormone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus." [GOC:BHF, GOC:vk]


id: GO:0034702
name: ion channel complex
namespace: cellular_component
def:
  "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient." [GOC:mah, ISBN:071673706X]


id: GO:0034709
name: methylosome
namespace: cellular_component
def:
  "A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains." [PMID:11713266, PMID:11756452]


id: GO:0034710
name: inhibin complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit." [GOC:BHF, GOC:mah]


id: GO:0034711
name: inhibin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers." [GOC:BHF, GOC:mah]


id: GO:0034713
name: type I transforming growth factor beta receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type I transforming growth factor beta receptor." [GOC:BHF, GOC:mah]


id: GO:0034714
name: type III transforming growth factor beta receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type III transforming growth factor beta receptor." [GOC:BHF, GOC:mah]


id: GO:0034715
name: pICln-Sm protein complex
namespace: cellular_component
def:
  "A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG." [GOC:mah, PMID:11713266]


id: GO:0034716
name: Gemin3-Gemin4-Gemin5 complex
namespace: cellular_component
def:
  "A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly." [GOC:mah, PMID:17640873]


id: GO:0034717
name: Gemin6-Gemin7-unrip complex
namespace: cellular_component
def:
  "A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly." [GOC:mah, PMID:17640873]


id: GO:0034718
name: SMN-Gemin2 complex
namespace: cellular_component
def:
  "A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex." [GOC:mah, PMID:17640873]


id: GO:0034719
name: SMN-Sm protein complex
namespace: cellular_component
def:
  "A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm." [PMID:11522829, PMID:17401408]


id: GO:0034720
name: histone H3-K4 demethylation
namespace: biological_process
def:
  "The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone." [GOC:mah]


id: GO:0034721
name: histone H3-K4 demethylation, trimethyl-H3-K4-specific
namespace: biological_process
def:
  "The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone." [GOC:mah]


id: GO:0034723
name: DNA replication-dependent nucleosome organization
namespace: biological_process
def:
  "The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation." [GOC:mah, PMID:17510629]


id: GO:0034724
name: DNA replication-independent nucleosome organization
namespace: biological_process
def:
  "The formation or destruction of chromatin structures, occurring outside the context of DNA replication." [GOC:mah, PMID:17510629]


id: GO:0034725
name: DNA replication-dependent nucleosome disassembly
namespace: biological_process
def:
  "The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation." [GOC:mah, PMID:17510629]


id: GO:0034726
name: DNA replication-independent nucleosome disassembly
namespace: biological_process
def:
  "The controlled breakdown of nucleosomes outside the context of DNA replication." [GOC:mah, PMID:17510629]


id: GO:0034728
name: nucleosome organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes." [GOC:mah]


id: GO:0034729
name: histone H3-K79 methylation
namespace: biological_process
def:
  "The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone." [GOC:se]


id: GO:0034730
name: SmD-containing SMN-Sm protein complex
namespace: cellular_component
def:
  "An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex." [PMID:12975319, PMID:17401408]


id: GO:0034731
name: Lsm-containing SMN-Sm protein complex
namespace: cellular_component
def:
  "An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA." [PMID:12975319, PMID:17401408]


id: GO:0034732
name: transcription factor TFIIIB-alpha complex
namespace: cellular_component
def:
  "A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters." [PMID:11433012]


id: GO:0034733
name: transcription factor TFIIIB-beta complex
namespace: cellular_component
def:
  "A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters." [PMID:11433012]


id: GO:0034734
name: transcription factor TFIIIC1 complex
namespace: cellular_component
def:
  "A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity." [GOC:mah, PMID:11433012, PMID:15096501]


id: GO:0034735
name: transcription factor TFIIIC2 complex
namespace: cellular_component
def:
  "A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter." [GOC:mah, PMID:11433012]


id: GO:0034736
name: cholesterol O-acyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA." [EC:2.3.1.26, RHEA:17732]


id: GO:0034739
name: histone deacetylase activity (H4-K16 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein." [EC:3.5.1.17, GOC:vw, RHEA:24551]


id: GO:0034740
name: TFIIIC-TOP1-SUB1 complex
namespace: cellular_component
def:
  "A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III." [PMID:9660958]


id: GO:0034741
name: APC-tubulin-IQGAP1 complex
namespace: cellular_component
def:
  "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization." [PMID:17126424]


id: GO:0034743
name: APC-IQGAP complex
namespace: cellular_component
def:
  "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129]


id: GO:0034744
name: APC-IQGAP1-Cdc42 complex
namespace: cellular_component
def:
  "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129]


id: GO:0034745
name: APC-IQGAP1-Rac1 complex
namespace: cellular_component
def:
  "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129]


id: GO:0034746
name: APC-IQGAP1-CLIP-170 complex
namespace: cellular_component
def:
  "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration." [PMID:15572129]


id: GO:0034748
name: Par3-APC-KIF3A complex
namespace: cellular_component
def:
  "A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity." [PMID:15556865]


id: GO:0034749
name: Scrib-APC complex
namespace: cellular_component
def:
  "A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation." [PMID:16611247]


id: GO:0034750
name: Scrib-APC-beta-catenin complex
namespace: cellular_component
def:
  "A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation." [PMID:16611247]


id: GO:0034751
name: aryl hydrocarbon receptor complex
namespace: cellular_component
def:
  "A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR." [GOC:mah, PMID:7598497]


id: GO:0034752
name: cytosolic aryl hydrocarbon receptor complex
namespace: cellular_component
def:
  "An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP." [PMID:7598497, PMID:8937476, PMID:9447995]


id: GO:0034753
name: nuclear aryl hydrocarbon receptor complex
namespace: cellular_component
def:
  "An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT)." [PMID:7598497]


id: GO:0034754
name: cellular hormone metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells." [GOC:mah]


id: GO:0034755
name: iron ion transmembrane transport
namespace: biological_process
def:
  "A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034756
name: regulation of iron ion transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034757
name: negative regulation of iron ion transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034758
name: positive regulation of iron ion transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034759
name: regulation of iron ion transmembrane transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034760
name: negative regulation of iron ion transmembrane transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034761
name: positive regulation of iron ion transmembrane transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034762
name: regulation of transmembrane transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]


id: GO:0034763
name: negative regulation of transmembrane transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]


id: GO:0034764
name: positive regulation of transmembrane transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]


id: GO:0034765
name: regulation of ion transmembrane transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]


id: GO:0034766
name: negative regulation of ion transmembrane transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]


id: GO:0034767
name: positive regulation of ion transmembrane transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]


id: GO:0034769
name: basement membrane disassembly
namespace: biological_process
def:
  "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221]


id: GO:0034770
name: histone H4-K20 methylation
namespace: biological_process
def:
  "The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone." [GOC:mah]


id: GO:0034771
name: histone H4-K20 monomethylation
namespace: biological_process
def:
  "The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone." [GOC:mah]


id: GO:0034772
name: histone H4-K20 dimethylation
namespace: biological_process
def:
  "The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone." [GOC:mah]


id: GO:0034773
name: histone H4-K20 trimethylation
namespace: biological_process
def:
  "The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone." [GOC:mah]


id: GO:0034775
name: glutathione transmembrane transport
namespace: biological_process
def:
  "A process in which glutathione is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0034776
name: response to histamine
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." [CHEBI:18295, GOC:BHF, GOC:mah, GOC:vk]


id: GO:0034778
name: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1003]


id: GO:0034779
name: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA." [UM-BBD_reactionID:r1004]


id: GO:0034780
name: glyphosate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-." [UM-BBD_reactionID:r0073]


id: GO:0034781
name: N-cyclohexylformamide amidohydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate." [UM-BBD_reactionID:r1030]


id: GO:0034783
name: pivalate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP." [UM-BBD_reactionID:r1032]


id: GO:0034785
name: salicylate 5-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+." [UM-BBD_reactionID:r1034]


id: GO:0034786
name: 9-fluorenone-3,4-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone." [UM-BBD_reactionID:r1039]


id: GO:0034787
name: 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-." [UM-BBD_reactionID:r1040]


id: GO:0034788
name: 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+." [UM-BBD_reactionID:r1041]


id: GO:0034789
name: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+." [UM-BBD_reactionID:r1042]


id: GO:0034790
name: 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-." [UM-BBD_reactionID:r1043]


id: GO:0034791
name: isobutylamine N-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O." [UM-BBD_reactionID:r1053]


id: GO:0034792
name: hypophosphite dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2." [UM-BBD_reactionID:r1058]


id: GO:0034793
name: cyclopropanecarboxylate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-." [UM-BBD_reactionID:r1056]


id: GO:0034795
name: cyclohexane monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O." [UM-BBD_reactionID:r1059]


id: GO:0034797
name: fosfomycin 2-glutathione ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid." [UM-BBD_reactionID:r1073]


id: GO:0034798
name: fosfomycin 2-L-cysteine ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid." [UM-BBD_reactionID:r1074]


id: GO:0034799
name: dihydride TNP tautomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form)." [UM-BBD_reactionID:r1070]


id: GO:0034800
name: trinitrophenol dihydride denitratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP." [UM-BBD_reactionID:r1067]


id: GO:0034801
name: 2,4-dinitrocyclohexanone hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate." [UM-BBD_reactionID:r1069]


id: GO:0034802
name: branched-chain dodecylbenzene sulfonate monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite." [UM-BBD_reactionID:r1079]


id: GO:0034803
name: 3-hydroxy-2-naphthoate 2,3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate." [UM-BBD_reactionID:r1104]


id: GO:0034804
name: benzo(a)pyrene 11,12-epoxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide." [UM-BBD_reactionID:r1119]


id: GO:0034805
name: benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-." [UM-BBD_reactionID:r1121]


id: GO:0034806
name: benzo(a)pyrene 11,12-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol." [UM-BBD_reactionID:r1124]


id: GO:0034807
name: 4,5-dihydroxybenzo(a)pyrene methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene." [UM-BBD_reactionID:r1131]


id: GO:0034808
name: benzo(a)pyrene 4,5-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol." [UM-BBD_reactionID:r1126]


id: GO:0034809
name: benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2." [UM-BBD_reactionID:r1127]


id: GO:0034810
name: 4,5-dihydroxybenzo(a)pyrene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate." [UM-BBD_reactionID:r1128]


id: GO:0034811
name: benzo(a)pyrene 9,10-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol." [UM-BBD_reactionID:r1132]


id: GO:0034812
name: 9,10-dihydroxybenzo(a)pyrene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate." [UM-BBD_reactionID:r1134]


id: GO:0034813
name: benzo(a)pyrene 7,8-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol." [UM-BBD_reactionID:1137]


id: GO:0034814
name: 7,8-dihydroxy benzo(a)pyrene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate." [UM-BBD_reactionID:r1138]


id: GO:0034815
name: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+." [UM-BBD_reactionID:r1135]


id: GO:0034816
name: anthracene 9,10-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol." [UM-BBD_reactionID:r1141]


id: GO:0034817
name: cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-." [UM-BBD_reactionID:r1144]


id: GO:0034818
name: ADD 9alpha-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin." [UM-BBD_reactionID:r1149]


id: GO:0034819
name: 3-HSA hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O." [UM-BBD_reactionID:r1150]


id: GO:0034820
name: 4,9-DSHA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+." [UM-BBD_reactionID:r1152]


id: GO:0034821
name: citronellol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+." [UM-BBD_reactionID:r1155]


id: GO:0034822
name: citronellal dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+." [UM-BBD_reactionID:r1156]


id: GO:0034823
name: citronellyl-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi." [UM-BBD_reactionID:r1157]


id: GO:0034824
name: citronellyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+." [UM-BBD_reactionID:r1159]


id: GO:0034825
name: tetralin ring-hydroxylating dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+." [UM-BBD_reactionID:r1169]


id: GO:0034826
name: 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+." [UM-BBD_reactionID:r1170]


id: GO:0034827
name: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+." [UM-BBD_reactionID:r1171]


id: GO:0034828
name: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+." [UM-BBD_reactionID:r1172]


id: GO:0034829
name: 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate." [UM-BBD_reactionID:r1172]


id: GO:0034830
name: (2Z)-2,4-dihydroxydec-2-enedioate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate." [UM-BBD_reactionID:r1174]


id: GO:0034831
name: (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-." [UM-BBD_reactionID:r1176]


id: GO:0034832
name: geranial dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+." [UM-BBD_reactionID:r1164]


id: GO:0034833
name: geranylate CoA-transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-." [UM-BBD_reactionID:r1165]


id: GO:0034834
name: 2-mercaptobenzothiazole dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol." [UM-BBD_reactionID:r1177]


id: GO:0034835
name: 2-mercaptobenzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole." [UM-BBD_reactionID:r1178]


id: GO:0034836
name: 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole." [UM-BBD_reactionID:r1181]


id: GO:0034837
name: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-." [UM-BBD_reactionID:r1179]


id: GO:0034838
name: menthone dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+." [UM-BBD_reactionID:r1183]


id: GO:0034839
name: menth-2-enone hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone." [UM-BBD_reactionID:r1184]


id: GO:0034840
name: 3-hydroxymenthone dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+." [UM-BBD_reactionID:r1185]


id: GO:0034841
name: mentha-1,3-dione-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA." [UM-BBD_reactionID:r1186]


id: GO:0034842
name: thiophene-2-carboxylate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi." [UM-BBD_reactionID:r1234]


id: GO:0034843
name: 2-oxoglutaryl-CoA thioesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH." [UM-BBD_reactionID:r1238]


id: GO:0034844
name: naphthyl-2-methyl-succinate CoA-transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate." [UM-BBD_reactionID:r1256]


id: GO:0034845
name: naphthyl-2-methyl-succinyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1258]


id: GO:0034846
name: naphthyl-2-methylene-succinyl-CoA lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA." [UM-BBD_reactionID:r1259]


id: GO:0034847
name: naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1260]


id: GO:0034848
name: naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA." [UM-BBD_reactionID:r1261]


id: GO:0034849
name: 2-naphthoate CoA-transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH." [UM-BBD_reactionID:r1262]


id: GO:0034850
name: isooctane monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol." [UM-BBD_reactionID:r1269]


id: GO:0034851
name: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA." [UM-BBD_reactionID:r1274]


id: GO:0034852
name: 4,4-dimethyl-3-oxopentanal dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-." [UM-BBD_reactionID:r1309]


id: GO:0034853
name: 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2." [UM-BBD_reactionID:r1278]


id: GO:0034854
name: 4,4-dimethyl-3-oxopentanoate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2." [UM-BBD_reactionID:r1280]


id: GO:0034855
name: 4-AD 9alpha-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O." [UM-BBD_reactionID:r1153]


id: GO:0034856
name: 2-hydroxyhexa-2,4-dienoate hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate." [UM-BBD_reactionID:r1281]


id: GO:0034857
name: 2-(methylthio)benzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole." [UM-BBD_reactionID:r1287]


id: GO:0034858
name: 2-hydroxybenzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole." [UM-BBD_reactionID:r1291]


id: GO:0034859
name: benzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole." [UM-BBD_reactionID:r1292]


id: GO:0034860
name: 2-mercaptobenzothiazole desulfurase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor." [UM-BBD_reactionID:r1288]


id: GO:0034861
name: benzothiazole-2-sulfonate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-." [UM-BBD_reactionID:r1290]


id: GO:0034862
name: 2,6-dihydroxybenzothiazole monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole." [UM-BBD_reactionID:r1294]


id: GO:0034863
name: 2,4,4-trimethyl-1-pentanol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-." [UM-BBD_reactionID:r1270]


id: GO:0034864
name: 2,4,4-trimethylpentanal dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-." [UM-BBD_reactionID:r1275]


id: GO:0034865
name: 2,4,4-trimethylpentanoate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-." [UM-BBD_reactionID:r1271]


id: GO:0034866
name: 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1276]


id: GO:0034867
name: 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA." [UM-BBD_reactionID:r1277]


id: GO:0034868
name: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1273]


id: GO:0034869
name: 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH." [UM-BBD_reactionID:r1307]


id: GO:0034870
name: pinacolone 5-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one." [UM-BBD_reactionID:r12979]


id: GO:0034871
name: 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-." [UM-BBD_reactionID:r1308]


id: GO:0034873
name: thioacetamide S-oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O." [UM-BBD_reactionID:r1312]


id: GO:0034874
name: thioacetamide S-oxide S-oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O." [UM-BBD_reactionID:r1313]


id: GO:0034875
name: caffeine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O." [UM-BBD_reactionID:r1321]


id: GO:0034877
name: isonicotinate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor." [UM-BBD_reactionID:r1337]


id: GO:0034878
name: 2-hydroxyisonicotinate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor." [UM-BBD_reactionID:r1338]


id: GO:0034879
name: 2,3,6-trihydroxyisonicotinate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2." [UM-BBD_reactionID:r1340]


id: GO:0034880
name: citrazinate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-." [UM-BBD_reactionID:r1339]


id: GO:0034883
name: obsolete isonicotinate reductase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate." [UM-BBD_reactionID:r1347]


id: GO:0034884
name: obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-." [UM-BBD_reactionID:r1349]


id: GO:0034885
name: gamma-N-formylaminovinylacetate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH." [UM-BBD_reactionID:r1350]


id: GO:0034886
name: gamma-aminovinylacetate deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3." [UM-BBD_reactionID:r1351]


id: GO:0034887
name: obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2." [UM-BBD_reactionID:r1348]


id: GO:0034888
name: endosulfan monooxygenase I activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O." [UM-BBD_reactionID:r1382]


id: GO:0034889
name: endosulfan hemisulfate sulfatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate." [UM-BBD_reactionID:r1384]


id: GO:0034891
name: endosulfan diol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-." [UM-BBD_reactionID:r1388]


id: GO:0034892
name: endosulfan lactone lactonase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+." [UM-BBD_reactionID:r1389]


id: GO:0034893
name: N-nitrodimethylamine hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O." [UM-BBD_reactionID:r1395]


id: GO:0034894
name: 4-hydroxypyridine-3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+." [UM-BBD_reactionID:r1397]


id: GO:0034895
name: pyridine-3,4-diol dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate." [UM-BBD_reactionID:r1398]


id: GO:0034896
name: 3-formiminopyruvate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3." [UM-BBD_reactionID:r1400]


id: GO:0034897
name: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol." [UM-BBD_reactionID:r1358]


id: GO:0034898
name: hexadecyltrimethylammonium chloride monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O." [UM-BBD_reactionID:r1373]


id: GO:0034899
name: trimethylamine monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O." [EC:1.14.13.148, UM-BBD_reactionID:r1407]


id: GO:0034900
name: 3-(N-formyl)-formiminopyruvate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate." [UM-BBD_reactionID:r1399]


id: GO:0034901
name: endosulfan hydroxyether dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-." [UM-BBD_reactionID:r1411]


id: GO:0034902
name: endosulfan sulfate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite." [UM-BBD_reactionID:r1387]


id: GO:0034903
name: endosulfan ether monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O." [UM-BBD_reactionID:r1413]


id: GO:0034904
name: 5-chloro-2-oxopent-4-enoate hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate." [UM-BBD_reactionID:r1436]


id: GO:0034905
name: 5-chloro-4-hydroxy-2-oxopentanate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde." [UM-BBD_reactionID:r1437]


id: GO:0034906
name: N-isopropylaniline 1,2-dixoxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine." [UM-BBD_reactionID:r0721]


id: GO:0034907
name: acetanilide 1,2-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide." [UM-BBD_reactionID:r0723]


id: GO:0034908
name: 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+." [UM-BBD_reactionID:r0724]


id: GO:0034909
name: 6-hydroxypseudooxynicotine dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine." [UM-BBD_reactionID:r1441]


id: GO:0034910
name: 6-hydroxy-3-succinoylpyridine hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine." [UM-BBD_reactionID:r1442]


id: GO:0034911
name: phthalate 3,4-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+." [UM-BBD_reactionID:r1444]


id: GO:0034912
name: phthalate 3,4-cis-dihydrodiol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+." [UM-BBD_reactionID:r1445]


id: GO:0034914
name: trinitrophenol hydride denitratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP." [UM-BBD_reactionID:r1448]


id: GO:0034915
name: 2-methylhexanoyl-CoA C-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA." [UM-BBD_reactionID:r0927]


id: GO:0034916
name: 2-methylhexanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-." [UM-BBD_reactionID:r0928]


id: GO:0034917
name: 2-methylhex-2-enoyl-CoA hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA." [UM-BBD_reactionID:r0929]


id: GO:0034918
name: 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0930]


id: GO:0034919
name: butyryl-CoA 2-C-propionyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA." [UM-BBD_reactionID:r0931]


id: GO:0034920
name: pyrene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene." [UM-BBD_reactionID:r0934]


id: GO:0034921
name: cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-." [UM-BBD_reactionID:r0935]


id: GO:0034922
name: 4,5-dihydroxypyrene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+." [UM-BBD_reactionID:r0936]


id: GO:0034923
name: phenanthrene-4,5-dicarboxylate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2." [UM-BBD_reactionID:r0937]


id: GO:0034924
name: cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2." [UM-BBD_reactionID:r0940]


id: GO:0034925
name: pyrene 4,5-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O." [UM-BBD_reactionID:r0941]


id: GO:0034926
name: pyrene-4,5-epoxide hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene." [UM-BBD_reactionID:r0942]


id: GO:0034927
name: pyrene 1,2-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O." [UM-BBD_reactionID:r0943]


id: GO:0034928
name: 1-hydroxypyrene 6,7-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O." [UM-BBD_reactionID:r0946]


id: GO:0034929
name: 1-hydroxypyrene 7,8-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O." [UM-BBD_reactionID:r0949]


id: GO:0034930
name: 1-hydroxypyrene sulfotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX." [UM-BBD_reactionID:r0952]


id: GO:0034931
name: 1-hydroxypyrene methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX." [UM-BBD_reactionID:r0953]


id: GO:0034932
name: 1-methoxypyrene 6,7-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O." [UM-BBD_reactionID:r0954]


id: GO:0034933
name: 1-hydroxy-6-methoxypyrene methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX." [UM-BBD_reactionID:r0956]


id: GO:0034934
name: phenanthrene-4-carboxylate dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate." [UM-BBD_reactionID:r0939]


id: GO:0034935
name: tetrachlorobenzene dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+." [UM-BBD_reactionID:r0957]


id: GO:0034936
name: 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+." [UM-BBD_reactionID:r0959]


id: GO:0034938
name: pyrrole-2-carboxylate monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O." [UM-BBD_reactionID:r0968]


id: GO:0034939
name: 5-hydroxypyrrole-2-carboxylate tautomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate." [UM-BBD_reactionID:r0969]


id: GO:0034940
name: 5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3." [UM-BBD_reactionID:r0984]


id: GO:0034942
name: cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi." [UM-BBD_reactionID:r0988]


id: GO:0034943
name: trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi." [UM-BBD_reactionID:r0989]


id: GO:0034944
name: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+." [UM-BBD_reactionID:r0986]


id: GO:0034945
name: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA." [UM-BBD_reactionID:r0987]


id: GO:0034946
name: 3-isopropylbut-3-enoyl-CoA thioesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH." [UM-BBD_reactionID:r0994]


id: GO:0034948
name: 2,6-dihydroxypseudooxynicotine hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate." [UM-BBD_reactionID:r0482]


id: GO:0034949
name: 1,1-dichloroethane reductive dehalogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl." [UM-BBD_reactionID:r1008]


id: GO:0034950
name: phenylboronic acid monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3." [UM-BBD_reactionID:r1020]


id: GO:0034951
name: o-hydroxylaminobenzoate mutase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate." [UM-BBD_reactionID:r1026]


id: GO:0034952
name: malonate semialdehyde decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2." [UM-BBD_reactionID:r0266]


id: GO:0034953
name: perillyl-CoA hydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA." [UM-BBD_reactionID:r1002]


id: GO:0034954
name: diphenyl ether 2,3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether." [UM-BBD_reactionID:r1450]


id: GO:0034955
name: 2,3-dihydroxydiphenyl ether dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol." [UM-BBD_reactionID:r1451]


id: GO:0034956
name: diphenyl ether 1,2-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+." [UM-BBD_reactionID:r1453]


id: GO:0034957
name: 3-nitrophenol nitroreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O." [UM-BBD_reactionID:r1495]


id: GO:0034958
name: aminohydroquinone monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3." [UM-BBD_reactionID:r1497]


id: GO:0034959
name: endothelin maturation
namespace: biological_process
def:
  "The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin." [GOC:BHF, GOC:rl]


id: GO:0034963
name: box C/D snoRNA processing
namespace: biological_process
def:
  "Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript into a mature box C/D snoRNA." [GOC:mah]


id: GO:0034964
name: box H/ACA snoRNA processing
namespace: biological_process
def:
  "Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript into a mature box H/ACA snoRNA." [GOC:mah]


id: GO:0034965
name: intronic box C/D snoRNA processing
namespace: biological_process
def:
  "Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA." [GOC:mah]


id: GO:0034966
name: intronic box H/ACA snoRNA processing
namespace: biological_process
def:
  "Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA." [GOC:mah]


id: GO:0034967
name: Set3 complex
namespace: cellular_component
def:
  "A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p." [GOC:ds, PMID:11711434]


id: GO:0034968
name: histone lysine methylation
namespace: biological_process
def:
  "The modification of a histone by addition of one or more methyl groups to a lysine residue." [GOC:mah, GOC:pr]


id: GO:0034970
name: histone H3-R2 methylation
namespace: biological_process
def:
  "The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone." [GOC:mah]


id: GO:0034971
name: histone H3-R17 methylation
namespace: biological_process
def:
  "The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone." [GOC:mah]


id: GO:0034972
name: histone H3-R26 methylation
namespace: biological_process
def:
  "The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone." [GOC:mah]


id: GO:0034973
name: Sid2-Mob1 complex
namespace: cellular_component
def:
  "A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex." [GOC:vw, PMID:10837231, PMID:15060149]


id: GO:0034974
name: Swi5-Swi2 complex
namespace: cellular_component
def:
  "A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching." [PMID:14663140]


id: GO:0034975
name: protein folding in endoplasmic reticulum
namespace: biological_process
def:
  "A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)." [GOC:mah, GOC:vw]


id: GO:0034976
name: response to endoplasmic reticulum stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:cjm, GOC:mah]


id: GO:0034977
name: ABIN2-NFKB1-MAP3K8 complex
namespace: cellular_component
def:
  "A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages." [PMID:15169888]


id: GO:0034978
name: PDX1-PBX1b-MRG1 complex
namespace: cellular_component
def:
  "A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes." [PMID:11279116, PMID:9710595]


id: GO:0034979
name: NAD-dependent protein deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD." [GOC:BHF, GOC:mah]


id: GO:0034980
name: FHL2-CREB complex
namespace: cellular_component
def:
  "A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation." [PMID:11046156]


id: GO:0034981
name: FHL3-CREB complex
namespace: cellular_component
def:
  "A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation." [PMID:11046156]


id: GO:0034982
name: mitochondrial protein processing
namespace: biological_process
def:
  "The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import." [GOC:curators]


id: GO:0034983
name: peptidyl-lysine deacetylation
namespace: biological_process
def:
  "The removal of an acetyl group from an acetylated lysine residue in a peptide or protein." [GOC:BHF, GOC:mah]


id: GO:0034985
name: Ecsit-NDUFAF1 complex
namespace: cellular_component
def:
  "Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed." [PMID:17344420]


id: GO:0034987
name: immunoglobulin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule." [GOC:BHF, GOC:vk]


id: GO:0034988
name: Fc-gamma receptor I complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG." [GOC:BHF, GOC:vk]


id: GO:0034990
name: nuclear mitotic cohesin complex
namespace: cellular_component
def:
  "A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex." [GOC:mah]


id: GO:0034991
name: nuclear meiotic cohesin complex
namespace: cellular_component
def:
  "A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the meiotic cohesin complex." [GOC:mah]


id: GO:0034992
name: microtubule organizing center attachment site
namespace: cellular_component
def:
  "A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope." [GOC:mah, PMID:18692466]


id: GO:0034993
name: LINC complex
namespace: cellular_component
def:
  "A protein complex that spans the nuclear outer and inner membranes, thereby linking the major cytoplasmic cytoskeleton elements to the nuclear lumen; the complex is conserved in eukaryotes and contains proteins with SUN and KASH domains." [GOC:mah, PMID:18692466]


id: GO:0034994
name: microtubule organizing center attachment site organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches." [GOC:mah, PMID:18692466]


id: GO:0034995
name: SC5b-7 complex
namespace: cellular_component
def:
  "A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly." [PMID:10090939]


id: GO:0034996
name: RasGAP-Fyn-Lyn-Yes complex
namespace: cellular_component
def:
  "A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation." [PMID:1544885]


id: GO:0034997
name: alphav-beta5 integrin-vitronectin complex
namespace: cellular_component
def:
  "A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin." [PMID:1694173, Reactome:REACT_14045.1]


id: GO:0034998
name: oligosaccharyltransferase I complex
namespace: cellular_component
def:
  "An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes." [PMID:15835887]


id: GO:0034999
name: oligosaccharyltransferase II complex
namespace: cellular_component
def:
  "An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes." [GOC:BHF, PMID:15835887]


id: GO:0035000
name: oligosaccharyltransferase III complex
namespace: cellular_component
def:
  "An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes." [PMID:15835887]


id: GO:0035001
name: dorsal trunk growth, open tracheal system
namespace: biological_process
def:
  "Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system." [GOC:mtg_sensu, ISBN:0879694238]


id: GO:0035002
name: liquid clearance, open tracheal system
namespace: biological_process
def:
  "The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system." [GOC:mtg_sensu, PMID:12571352]


id: GO:0035003
name: subapical complex
namespace: cellular_component
def:
  "The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells." [PMID:11752566, PMID:12500938]


id: GO:0035004
name: phosphatidylinositol 3-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring." [GOC:bf, PMID:10209156, PMID:9255069]


id: GO:0035005
name: 1-phosphatidylinositol-4-phosphate 3-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.154, RHEA:18376]


id: GO:0035006
name: melanization defense response
namespace: biological_process
def:
  "The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin." [GOC:bf, PMID:12408809]


id: GO:0035007
name: regulation of melanization defense response
namespace: biological_process
def:
  "Any process that affects the rate, extent or location of the melanization defense response during injury or invasion." [GOC:bf]


id: GO:0035008
name: positive regulation of melanization defense response
namespace: biological_process
def:
  "Any process that increases the rate or extent of the melanization defense response during injury or invasion." [GOC:bf]


id: GO:0035009
name: negative regulation of melanization defense response
namespace: biological_process
def:
  "Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection." [GOC:bf, PMID:12408809]


id: GO:0035010
name: encapsulation of foreign target
namespace: biological_process
def:
  "Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization." [GO_REF:0000022, GOC:bf, GOC:mtg_15nov05, PMID:11846478, PMID:12225920]


id: GO:0035014
name: phosphatidylinositol 3-kinase regulator activity
namespace: molecular_function
def:
  "Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates." [GOC:bf, PMID:9255069]


id: GO:0035015
name: elongation of arista core
namespace: biological_process
def:
  "The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions." [GOC:bf, PMID:11404081]


id: GO:0035016
name: elongation of arista lateral
namespace: biological_process
def:
  "The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions." [GOC:bf, PMID:11404081]


id: GO:0035017
name: cuticle pattern formation
namespace: biological_process
def:
  "The regionalization process that gives rise to the patterns of cell differentiation in the cuticle." [GOC:bf]


id: GO:0035018
name: adult chitin-based cuticle pattern formation
namespace: biological_process
def:
  "The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035019
name: somatic stem cell population maintenance
namespace: biological_process
def:
  "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089]


id: GO:0035020
name: regulation of Rac protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Rac protein signal transduction." [GOC:bf]


id: GO:0035021
name: negative regulation of Rac protein signal transduction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction." [GOC:bf]


id: GO:0035022
name: positive regulation of Rac protein signal transduction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction." [GOC:bf]


id: GO:0035023
name: regulation of Rho protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Rho protein signal transduction." [GOC:bf]


id: GO:0035024
name: negative regulation of Rho protein signal transduction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction." [GOC:bf]


id: GO:0035025
name: positive regulation of Rho protein signal transduction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction." [GOC:bf]


id: GO:0035026
name: leading edge cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet." [GOC:bf]


id: GO:0035027
name: leading edge cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet." [GOC:bf]


id: GO:0035028
name: leading edge cell fate determination
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:bf]


id: GO:0035029
name: dorsal closure, leading edge cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis." [GOC:bf]


id: GO:0035032
name: phosphatidylinositol 3-kinase complex, class III
namespace: cellular_component
def:
  "A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI)." [GOC:bf, PMID:9255069]


id: GO:0035036
name: sperm-egg recognition
namespace: biological_process
def:
  "The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization." [GOC:bf]


id: GO:0035037
name: sperm entry
namespace: biological_process
def:
  "An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur." [GOC:bf, PMID:9630751]


id: GO:0035039
name: male pronucleus assembly
namespace: biological_process
def:
  "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001]


id: GO:0035040
name: sperm nuclear envelope removal
namespace: biological_process
def:
  "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001]


id: GO:0035041
name: sperm chromatin decondensation
namespace: biological_process
def:
  "Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus." [GOC:bf, PMID:11735001]


id: GO:0035042
name: fertilization, exchange of chromosomal proteins
namespace: biological_process
def:
  "Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity." [GOC:bf, PMID:11735001]


id: GO:0035043
name: male pronuclear envelope synthesis
namespace: biological_process
def:
  "Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation." [GOC:bf, PMID:11735001]


id: GO:0035044
name: sperm aster formation
namespace: biological_process
def:
  "Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei." [GOC:bf, ISBN:0879694238]


id: GO:0035045
name: sperm plasma membrane disassembly
namespace: biological_process
def:
  "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238]


id: GO:0035046
name: pronuclear migration
namespace: biological_process
def:
  "The directed movement of the male and female pronuclei towards each other prior to their fusion." [GOC:bf, PMID:9199363]


id: GO:0035047
name: centrosomal and pronuclear rotation
namespace: biological_process
def:
  "The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion." [GOC:bf, ISBN:087969307X, PMID:10085292]


id: GO:0035048
name: splicing factor protein import into nucleus
namespace: biological_process
def:
  "The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:bf]


id: GO:0035050
name: embryonic heart tube development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators]


id: GO:0035051
name: cardiocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf]


id: GO:0035052
name: dorsal vessel aortic cell fate commitment
namespace: biological_process
def:
  "The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12397110]


id: GO:0035053
name: dorsal vessel heart proper cell fate commitment
namespace: biological_process
def:
  "The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12397110]


id: GO:0035054
name: embryonic heart tube anterior/posterior pattern specification
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta." [GOC:bf, PMID:12435360]


id: GO:0035058
name: nonmotile primary cilium assembly
namespace: biological_process
def:
  "The assembly of a primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules." [GOC:kmv, PMID:14521833, PMID:14521834]


id: GO:0035059
name: RCAF complex
namespace: cellular_component
def:
  "A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4." [GOC:bf, PMID:10591219]


id: GO:0035060
name: brahma complex
namespace: cellular_component
def:
  "A SWI/SNF-type complex that contains the ATPase product of the Drosophila brahma gene, or an ortholog thereof." [GOC:bf, PMID:10809665, PMID:12482982]


id: GO:0035061
name: interchromatin granule
namespace: cellular_component
def:
  "A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439]


id: GO:0035062
name: omega speckle
namespace: cellular_component
def:
  "A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439]


id: GO:0035063
name: nuclear speck organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized." [GOC:bf, GOC:curators]


id: GO:0035064
name: methylated histone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf, PMID:14585615]


id: GO:0035065
name: regulation of histone acetylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf]


id: GO:0035066
name: positive regulation of histone acetylation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf]


id: GO:0035067
name: negative regulation of histone acetylation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf]


id: GO:0035068
name: micro-ribonucleoprotein complex
namespace: cellular_component
def:
  "A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA." [GOC:bf, PMID:14559182]


id: GO:0035069
name: larval midgut histolysis
namespace: biological_process
def:
  "The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly." [GOC:bf, GOC:dph, GOC:mtg_apoptosis, PMID:9409683]


id: GO:0035070
name: salivary gland histolysis
namespace: biological_process
def:
  "The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly." [GOC:bf, GOC:dph, GOC:mtg_apoptosis, PMID:9409683]


id: GO:0035071
name: salivary gland cell autophagic cell death
namespace: biological_process
def:
  "The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis." [GOC:bf, GOC:mtg_apoptosis, PMID:10882130]


id: GO:0035072
name: ecdysone-mediated induction of salivary gland cell autophagic cell death
namespace: biological_process
def:
  "Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis." [GOC:bf]


id: GO:0035073
name: pupariation
namespace: biological_process
def:
  "The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis." [GOC:bf, ISBN:0879694238, PMID:9409683]


id: GO:0035074
name: pupation
namespace: biological_process
def:
  "The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period." [GOC:bf, ISBN:0582227089, ISBN:0879694238]


id: GO:0035075
name: response to ecdysone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus." [GOC:bf]


id: GO:0035076
name: ecdysone receptor-mediated signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex." [GOC:bf]


id: GO:0035077
name: ecdysone-mediated polytene chromosome puffing
namespace: biological_process
def:
  "The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation." [GOC:bf, PMID:12543962]


id: GO:0035078
name: induction of programmed cell death by ecdysone
namespace: biological_process
def:
  "Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death." [GOC:bf]


id: GO:0035079
name: polytene chromosome puffing
namespace: biological_process
def:
  "The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals." [GOC:bf, PMID:12543962]


id: GO:0035080
name: heat shock-mediated polytene chromosome puffing
namespace: biological_process
def:
  "The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus." [GOC:bf, PMID:12543962]


id: GO:0035081
name: induction of programmed cell death by hormones
namespace: biological_process
def:
  "Any process induced by hormones that directly activates any of the steps required for programmed cell death." [GOC:bf]


id: GO:0035082
name: axoneme assembly
namespace: biological_process
def:
  "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194]


id: GO:0035087
name: siRNA loading onto RISC involved in RNA interference
namespace: biological_process
def:
  "The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference." [GOC:bf, GOC:mah, PMID:14512631]


id: GO:0035088
name: establishment or maintenance of apical/basal cell polarity
namespace: biological_process
def:
  "Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components." [GOC:bf, GOC:mah, PMID:10934483]


id: GO:0035091
name: phosphatidylinositol binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, ISBN:0198506732, PMID:11395417]


id: GO:0035092
name: sperm chromatin condensation
namespace: biological_process
def:
  "The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication." [GOC:bf, PMID:11735001]


id: GO:0035093
name: spermatogenesis, exchange of chromosomal proteins
namespace: biological_process
def:
  "The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin." [GOC:bf, PMID:11735001]


id: GO:0035094
name: response to nicotine
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus." [CHEBI:17688, GOC:bf, GOC:ef, ISBN:0198506732, ISBN:0582227089]


id: GO:0035095
name: behavioral response to nicotine
namespace: biological_process
def:
  "Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus." [GOC:bf, ISBN:0198506732]


id: GO:0035096
name: larval midgut cell programmed cell death
namespace: biological_process
def:
  "The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ." [GOC:bf, GOC:mtg_apoptosis]


id: GO:0035097
name: histone methyltransferase complex
namespace: cellular_component
def:
  "A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins." [GOC:bf]


id: GO:0035098
name: ESC/E(Z) complex
namespace: cellular_component
def:
  "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375]


id: GO:0035099
name: hemocyte migration
namespace: biological_process
def:
  "The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo." [GOC:bf, GOC:mtg_sensu, PMID:12885551]


id: GO:0035100
name: ecdysone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting." [GOC:bf, ISBN:0198506732, ISBN:0582227089]


id: GO:0035101
name: FACT complex
namespace: cellular_component
def:
  "An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer." [GOC:bf, GOC:expert_ks, GOC:expert_ras, GOC:expert_tf, GOC:krc, PMID:12934006, PMID:12934007, PMID:16678108]


id: GO:0035102
name: PRC1 complex
namespace: cellular_component
def:
  "A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling." [GOC:bf, PMID:10412979]


id: GO:0035103
name: sterol regulatory element binding protein cleavage
namespace: biological_process
def:
  "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids." [GOC:bf, GOC:vw, PMID:12923525]


id: GO:0035105
name: sterol regulatory element binding protein import into nucleus
namespace: biological_process
def:
  "The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, GOC:vw, PMID:12923525]


id: GO:0035106
name: operant conditioning
namespace: biological_process
def:
  "Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior." [PMID:14662373]


id: GO:0035107
name: appendage morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089]


id: GO:0035108
name: limb morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping." [UBERON:0002101]


id: GO:0035109
name: obsolete imaginal disc-derived limb morphogenesis
namespace: biological_process
def:
  "OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035110
name: obsolete leg morphogenesis
namespace: biological_process
def:
  "OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands." [GOC:bf, ISBN:0198612001]


id: GO:0035111
name: obsolete leg joint morphogenesis
namespace: biological_process
def:
  "OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur." [GOC:bf, ISBN:0582227089, PMID:12051824]


id: GO:0035112
name: genitalia morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf]


id: GO:0035113
name: embryonic appendage morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089]


id: GO:0035114
name: imaginal disc-derived appendage morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism." [GOC:mtg_sensu, ISBN:0582227089]


id: GO:0035115
name: embryonic forelimb morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [ISBN:0198612001]


id: GO:0035116
name: embryonic hindlimb morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal." [ISBN:0198612001]


id: GO:0035118
name: embryonic pectoral fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035119
name: embryonic pelvic fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035120
name: post-embryonic appendage morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089]


id: GO:0035121
name: obsolete tail morphogenesis
namespace: biological_process
def:
  "OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals." [ISBN:0198612001]


id: GO:0035122
name: embryonic medial fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh]


id: GO:0035123
name: embryonic dorsal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh]


id: GO:0035124
name: embryonic caudal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion." [GOC:dgh]


id: GO:0035125
name: embryonic anal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh]


id: GO:0035126
name: post-embryonic genitalia morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized." [GOC:bf]


id: GO:0035127
name: post-embryonic limb morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping." [ISBN:0395825172]


id: GO:0035128
name: post-embryonic forelimb morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism." [GOC:bf]


id: GO:0035129
name: post-embryonic hindlimb morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized." [GOC:bf]


id: GO:0035130
name: post-embryonic pectoral fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035131
name: post-embryonic pelvic fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035132
name: post-embryonic medial fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh]


id: GO:0035133
name: post-embryonic caudal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion." [GOC:dgh]


id: GO:0035134
name: post-embryonic dorsal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh]


id: GO:0035135
name: post-embryonic anal fin morphogenesis
namespace: biological_process
def:
  "The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh]


id: GO:0035136
name: forelimb morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [GOC:go_curators]


id: GO:0035137
name: hindlimb morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the hindlimb are generated and organized." [GOC:go_curators]


id: GO:0035138
name: pectoral fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035139
name: pelvic fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh]


id: GO:0035141
name: medial fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh]


id: GO:0035142
name: dorsal fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh]


id: GO:0035143
name: caudal fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion." [GOC:dgh]


id: GO:0035144
name: anal fin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh]


id: GO:0035145
name: exon-exon junction complex
namespace: cellular_component
def:
  "A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay." [PMID:11532962, PMID:11743026]


id: GO:0035147
name: branch fusion, open tracheal system
namespace: biological_process
def:
  "Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint." [GOC:mtg_sensu, PMID:14570584]


id: GO:0035148
name: tube formation
namespace: biological_process
def:
  "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf]


id: GO:0035149
name: lumen formation, open tracheal system
namespace: biological_process
def:
  "Creation of the central hole of a tube in an open tracheal system through which gases flow." [GOC:bf, GOC:mtg_sensu]


id: GO:0035150
name: regulation of tube size
namespace: biological_process
def:
  "Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes." [PMID:10887083]


id: GO:0035151
name: regulation of tube size, open tracheal system
namespace: biological_process
def:
  "Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape." [GOC:mtg_sensu, PMID:10887083, PMID:12930776, PMID:12973360]


id: GO:0035152
name: regulation of tube architecture, open tracheal system
namespace: biological_process
def:
  "Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network." [GOC:mtg_sensu, PMID:14570584]


id: GO:0035153
name: epithelial cell type specification, open tracheal system
namespace: biological_process
def:
  "Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions." [GOC:mtg_sensu, PMID:10684581, PMID:11063940]


id: GO:0035154
name: terminal cell fate specification, open tracheal system
namespace: biological_process
def:
  "The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange." [GOC:mtg_sensu, PMID:10684581, PMID:11063940]


id: GO:0035155
name: negative regulation of terminal cell fate specification, open tracheal system
namespace: biological_process
def:
  "Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [GOC:mtg_sensu, PMID:10684581]


id: GO:0035156
name: fusion cell fate specification
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion." [PMID:11063940]


id: GO:0035157
name: negative regulation of fusion cell fate specification
namespace: biological_process
def:
  "Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [PMID:10684581]


id: GO:0035158
name: regulation of tube diameter, open tracheal system
namespace: biological_process
def:
  "Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size." [GOC:mtg_sensu, PMID:14570584]


id: GO:0035160
name: maintenance of epithelial integrity, open tracheal system
namespace: biological_process
def:
  "Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process." [GOC:mtg_sensu, PMID:10694415, PMID:14681183]


id: GO:0035161
name: imaginal disc lineage restriction
namespace: biological_process
def:
  "Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf, PMID:10625531, PMID:9374402]


id: GO:0035163
name: embryonic hemocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu, PMID:14602069]


id: GO:0035164
name: embryonic plasmatocyte differentiation
namespace: biological_process
def:
  "The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte." [GOC:bf, PMID:11921077, PMID:8174791]


id: GO:0035165
name: embryonic crystal cell differentiation
namespace: biological_process
def:
  "The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm]


id: GO:0035166
name: post-embryonic hemopoiesis
namespace: biological_process
def:
  "The stages of blood cell formation that take place after completion of embryonic development." [GOC:bf]


id: GO:0035167
name: larval lymph gland hemopoiesis
namespace: biological_process
def:
  "The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages." [GOC:bf, GOC:mtg_sensu, PMID:12445385]


id: GO:0035168
name: larval lymph gland hemocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:14602069]


id: GO:0035169
name: lymph gland plasmatocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte." [GOC:bf, PMID:11921077, PMID:8174791]


id: GO:0035170
name: lymph gland crystal cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm]


id: GO:0035171
name: lamellocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [GOC:bf, PMID:14734104]


id: GO:0035172
name: hemocyte proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu]


id: GO:0035173
name: histone kinase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf]


id: GO:0035174
name: histone serine kinase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf]


id: GO:0035175
name: histone kinase activity (H3-S10 specific)
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3." [GOC:bf, PMID:15041176]


id: GO:0035176
name: social behavior
namespace: biological_process
def:
  "Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group." [GOC:jh2, PMID:12848939, Wikipedia:Social_behavior]


id: GO:0035178
name: turning behavior
namespace: biological_process
def:
  "Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source." [PMID:10880478]


id: GO:0035179
name: larval turning behavior
namespace: biological_process
def:
  "Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source." [PMID:10880478]


id: GO:0035180
name: larval wandering behavior
namespace: biological_process
def:
  "The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction." [PMID:12848927, PMID:12956960]


id: GO:0035181
name: larval burrowing behavior
namespace: biological_process
def:
  "Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation." [PMID:12848927, PMID:12848939]


id: GO:0035182
name: female germline ring canal outer rim
namespace: cellular_component
def:
  "An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues." [PMID:12435357, PMID:7925006]


id: GO:0035183
name: female germline ring canal inner rim
namespace: cellular_component
def:
  "A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins." [PMID:10556087, PMID:7925006, PMID:9093858]


id: GO:0035184
name: histone threonine kinase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf]


id: GO:0035185
name: preblastoderm mitotic cell cycle
namespace: biological_process
def:
  "The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis." [ISBN:0879694238]


id: GO:0035186
name: syncytial blastoderm mitotic cell cycle
namespace: biological_process
def:
  "Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively." [ISBN:0879694238]


id: GO:0035187
name: hatching behavior
namespace: biological_process
def:
  "The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell." [GOC:pr, PMID:10436051]


id: GO:0035188
name: hatching
namespace: biological_process
def:
  "The emergence of an immature organism from a protective structure." [GOC:dgh, GOC:isa_complete, ISBN:0198612001]


id: GO:0035189
name: Rb-E2F complex
namespace: cellular_component
def:
  "A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression." [PMID:14616073]


id: GO:0035190
name: syncytial nuclear migration
namespace: biological_process
def:
  "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839]


id: GO:0035191
name: nuclear axial expansion
namespace: biological_process
def:
  "The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex." [PMID:8314839]


id: GO:0035192
name: nuclear cortical migration
namespace: biological_process
def:
  "The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo." [PMID:8314839]


id: GO:0035193
name: larval central nervous system remodeling
namespace: biological_process
def:
  "Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster." [GOC:sensu, PMID:9647692]


id: GO:0035194
name: posttranscriptional gene silencing by RNA
namespace: biological_process
def:
  "Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger mRNA degradation or negatively regulate translation." [GOC:mah, PMID:15020054, PMID:15066275, PMID:15066283]


id: GO:0035195
name: gene silencing by miRNA
namespace: biological_process
def:
  "Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of mRNA cleavage or translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA." [PMID:14744438, PMID:15066275, PMID:15066283, PMID:23209154]


id: GO:0035196
name: production of miRNAs involved in gene silencing by miRNA
namespace: biological_process
def:
  "Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein." [GOC:dph, GOC:tb, PMID:15066275, PMID:15066283]


id: GO:0035197
name: siRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme." [PMID:15066275, PMID:15066283]


id: GO:0035198
name: miRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes." [PMID:15066283]


id: GO:0035199
name: salt aversion
namespace: biological_process
def:
  "The specific avoidance actions or reactions of an organism in response to the perception of salt." [GOC:bf]


id: GO:0035200
name: leg disc anterior/posterior pattern formation
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc." [GOC:bf]


id: GO:0035201
name: leg disc anterior/posterior lineage restriction
namespace: biological_process
def:
  "Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf]


id: GO:0035202
name: tracheal pit formation in open tracheal system
namespace: biological_process
def:
  "Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11063940, PMID:11992723, PMID:14570584]


id: GO:0035203
name: regulation of lamellocyte differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104]


id: GO:0035204
name: negative regulation of lamellocyte differentiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104]


id: GO:0035205
name: positive regulation of lamellocyte differentiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104]


id: GO:0035206
name: regulation of hemocyte proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035207
name: negative regulation of hemocyte proliferation
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035208
name: positive regulation of hemocyte proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035209
name: pupal development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis." [GOC:bf, GOC:mtg_sensu]


id: GO:0035210
name: prepupal development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation." [GOC:mtg_sensu, http://sdb.bio.purdue.edu/fly/aimain/1adult.htm]


id: GO:0035211
name: spermathecum morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk." [PMID:12679097]


id: GO:0035212
name: cell competition in a multicellular organism
namespace: biological_process
def:
  "Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells." [GOC:bf, PMID:1116643, PMID:15066286]


id: GO:0035213
name: clypeo-labral disc development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite." [GOC:bf, ISBN:0879694238]


id: GO:0035214
name: eye-antennal disc development
namespace: biological_process
def:
  "Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238]


id: GO:0035215
name: genital disc development
namespace: biological_process
def:
  "Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia." [GOC:bf, ISBN:0879694238, PMID:11494318]


id: GO:0035216
name: haltere disc development
namespace: biological_process
def:
  "Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum." [GOC:bf, ISBN:0879694238]


id: GO:0035217
name: labial disc development
namespace: biological_process
def:
  "Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis." [GOC:bf, ISBN:0879694238]


id: GO:0035218
name: leg disc development
namespace: biological_process
def:
  "Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura." [GOC:bf, ISBN:0879694238]


id: GO:0035219
name: prothoracic disc development
namespace: biological_process
def:
  "Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle." [GOC:bf, ISBN:0879694238]


id: GO:0035220
name: wing disc development
namespace: biological_process
def:
  "Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura." [GOC:bf, ISBN:0879694238]


id: GO:0035221
name: genital disc pattern formation
namespace: biological_process
def:
  "The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc." [GOC:bf]


id: GO:0035222
name: wing disc pattern formation
namespace: biological_process
def:
  "The process giving rise to the pattern of cell differentiation in the wing imaginal disc." [GOC:bf]


id: GO:0035223
name: leg disc pattern formation
namespace: biological_process
def:
  "The process that gives rise to the patterns of cell differentiation in the leg imaginal disc." [GOC:bf]


id: GO:0035224
name: genital disc anterior/posterior pattern formation
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium)." [PMID:11494318]


id: GO:0035225
name: determination of genital disc primordium
namespace: biological_process
def:
  "Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two." [GOC:bf, PMID:11494318]


id: GO:0035226
name: glutamate-cysteine ligase catalytic subunit binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase." [PMID:12954617]


id: GO:0035229
name: positive regulation of glutamate-cysteine ligase activity
namespace: biological_process
def:
  "Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate." [PMID:12954617]


id: GO:0035230
name: cytoneme
namespace: cellular_component
def:
  "A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um." [PMID:10367889, PMID:10675901]


id: GO:0035231
name: cytoneme assembly
namespace: biological_process
def:
  "Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell." [PMID:10367889, PMID:10675901]


id: GO:0035232
name: germ cell attraction
namespace: biological_process
def:
  "The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target." [PMID:12885551]


id: GO:0035233
name: germ cell repulsion
namespace: biological_process
def:
  "The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue." [PMID:12885551]


id: GO:0035234
name: ectopic germ cell programmed cell death
namespace: biological_process
def:
  "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944]


id: GO:0035235
name: ionotropic glutamate receptor signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:0198506732]


id: GO:0035238
name: vitamin A biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids." [PMID:11158606]


id: GO:0035239
name: tube morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839]


id: GO:0035240
name: dopamine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." [ISBN:0198506732]


id: GO:0035241
name: protein-arginine omega-N monomethyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue." [PMID:14705965, RESID:AA0069]


id: GO:0035242
name: protein-arginine omega-N asymmetric methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues." [PMID:14705965, RESID:AA0068, RESID:AA0069]


id: GO:0035243
name: protein-arginine omega-N symmetric methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues." [PMID:14705965, RESID:AA0067, RESID:AA0069]


id: GO:0035244
name: peptidyl-arginine C-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein." [GOC:bf]


id: GO:0035247
name: peptidyl-arginine omega-N-methylation
namespace: biological_process
def:
  "The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein." [PMID:14705965, RESID:AA0067, RESID:AA0068, RESID:AA0069]


id: GO:0035248
name: alpha-1,4-N-acetylgalactosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage." [PMID:15130086]


id: GO:0035249
name: synaptic transmission, glutamatergic
namespace: biological_process
def:
  "The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:kmv]


id: GO:0035250
name: UDP-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html]


id: GO:0035251
name: UDP-glucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html]


id: GO:0035252
name: UDP-xylosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html]


id: GO:0035253
name: ciliary rootlet
namespace: cellular_component
def:
  "A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm." [GOC:cilia, PMID:12427867]


id: GO:0035255
name: ionotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels." [GOC:bf, ISBN:0198506732]


id: GO:0035256
name: G-protein coupled glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a G-protein coupled glutamate receptor (a metabotropic glutamate receptor)." [GOC:bf, ISBN:0198506732, PMID:9069287]


id: GO:0035257
name: nuclear hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell." [GOC:bf]


id: GO:0035260
name: internal genitalia morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html]


id: GO:0035261
name: external genitalia morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html]


id: GO:0035262
name: gonad morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001]


id: GO:0035263
name: genital disc sexually dimorphic development
namespace: biological_process
def:
  "The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed." [PMID:11290302, PMID:11494318, PMID:11702781]


id: GO:0035264
name: multicellular organism growth
namespace: biological_process
def:
  "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb]


id: GO:0035265
name: organ growth
namespace: biological_process
def:
  "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544]


id: GO:0035266
name: meristem growth
namespace: biological_process
def:
  "The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation." [GOC:bf, ISBN:0198547684]


id: GO:0035267
name: NuA4 histone acetyltransferase complex
namespace: cellular_component
def:
  "A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60)." [GOC:ecd, PMID:10966108, PMID:14966270]


id: GO:0035269
name: protein O-linked mannosylation
namespace: biological_process
def:
  "The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage." [GOC:bf, PMID:9878797]


id: GO:0035270
name: endocrine system development
namespace: biological_process
def:
  "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, http://encyclopedia.thefreedictionary.com/Endocrine+sytem, ISBN:0198506732]


id: GO:0035271
name: ring gland development
namespace: biological_process
def:
  "Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones." [GOC:bf, PMID:11223816, PMID:9584098]


id: GO:0035272
name: exocrine system development
namespace: biological_process
def:
  "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, http://encyclopedia.thefreedictionary.com/Exocrine+gland, ISBN:0198506732]


id: GO:0035273
name: phthalate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a phthalate, any ester or salt of phthalic acid." [http://umbbd.ahc.umn.edu/pth/pth_map.html]


id: GO:0035274
name: diphenyl phthalate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with diphenyl phthalate, C(20)H(14)O(4)." [http://www.sigmaaldrich.com]


id: GO:0035275
name: dibutyl phthalate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with dibutyl phthalate, C(16)H(22)O(4)." [http://www.sigmaaldrich.com]


id: GO:0035277
name: spiracle morphogenesis, open tracheal system
namespace: biological_process
def:
  "The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk." [GOC:mtg_sensu, PMID:10491268]


id: GO:0035278
name: miRNA mediated inhibition of translation
namespace: biological_process
def:
  "The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs" [PMID:14744438, PMID:15196554]


id: GO:0035279
name: mRNA cleavage involved in gene silencing by miRNA
namespace: biological_process
def:
  "The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism." [GOC:dph, GOC:mtg_lung, PMID:14744438, PMID:15196554]


id: GO:0035280
name: miRNA loading onto RISC involved in gene silencing by miRNA
namespace: biological_process
def:
  "The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC)." [PMID:14744438]


id: GO:0035281
name: pre-miRNA export from nucleus
namespace: biological_process
def:
  "Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product." [GOC:sl, PMID:14744438]


id: GO:0035282
name: segmentation
namespace: biological_process
def:
  "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689]


id: GO:0035283
name: central nervous system segmentation
namespace: biological_process
def:
  "Division of the central nervous system into a series of semi-repetitive parts or segments." [GOC:bf]


id: GO:0035285
name: appendage segmentation
namespace: biological_process
def:
  "Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented." [PMID:10357895]


id: GO:0035286
name: obsolete leg segmentation
namespace: biological_process
def:
  "OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint." [PMID:10357895]


id: GO:0035287
name: head segmentation
namespace: biological_process
def:
  "Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial)." [PMID:10477305, PMID:7915837]


id: GO:0035288
name: anterior head segmentation
namespace: biological_process
def:
  "Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments." [PMID:15382136]


id: GO:0035289
name: posterior head segmentation
namespace: biological_process
def:
  "Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains." [PMID:15382136]


id: GO:0035290
name: trunk segmentation
namespace: biological_process
def:
  "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402]


id: GO:0035291
name: specification of segmental identity, intercalary segment
namespace: biological_process
def:
  "The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437, PMID:10477305]


id: GO:0035292
name: specification of segmental identity, trunk
namespace: biological_process
def:
  "The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [PMID:1360402]


id: GO:0035293
name: chitin-based larval cuticle pattern formation
namespace: biological_process
def:
  "The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0035294
name: determination of wing disc primordium
namespace: biological_process
def:
  "Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc." [ISBN:0879694238]


id: GO:0035295
name: tube development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790]


id: GO:0035297
name: regulation of Malpighian tubule diameter
namespace: biological_process
def:
  "Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells." [PMID:9286684]


id: GO:0035299
name: inositol pentakisphosphate 2-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+)." [EC:2.7.1.158, RHEA:20316]


id: GO:0035300
name: obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate." [EC:2.7.1.159, PMID:9126335]


id: GO:0035301
name: Hedgehog signaling complex
namespace: cellular_component
def:
  "A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila)." [PMID:10825151, PMID:15057936]


id: GO:0035302
name: ecdysteroid 25-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods." [ISBN:0198506732, PMID:15350618]


id: GO:0035303
name: regulation of dephosphorylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf]


id: GO:0035304
name: regulation of protein dephosphorylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf]


id: GO:0035305
name: negative regulation of dephosphorylation
namespace: biological_process
def:
  "Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf]


id: GO:0035306
name: positive regulation of dephosphorylation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf]


id: GO:0035307
name: positive regulation of protein dephosphorylation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf]


id: GO:0035308
name: negative regulation of protein dephosphorylation
namespace: biological_process
def:
  "Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf]


id: GO:0035309
name: wing and notum subfield formation
namespace: biological_process
def:
  "The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures." [PMID:10860999]


id: GO:0035310
name: notum cell fate specification
namespace: biological_process
def:
  "The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment." [PMID:10860999]


id: GO:0035311
name: wing cell fate specification
namespace: biological_process
def:
  "The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment." [PMID:10860999]


id: GO:0035312
name: 5'-3' exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule." [ISBN:0198547684]


id: GO:0035313
name: wound healing, spreading of epidermal cells
namespace: biological_process
def:
  "The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis." [GOC:bf, PMID:15269788]


id: GO:0035314
name: scab formation
namespace: biological_process
def:
  "Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection." [GOC:bf, PMID:15269788]


id: GO:0035315
name: hair cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a hair cell." [GOC:bf]


id: GO:0035316
name: non-sensory hair organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis." [GOC:mtg_sensu, PMID:11064425]


id: GO:0035317
name: imaginal disc-derived wing hair organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11064425, PMID:12540853]


id: GO:0035318
name: imaginal disc-derived wing hair outgrowth
namespace: biological_process
def:
  "Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair." [GOC:mtg_sensu, PMID:11064425, PMID:8947551]


id: GO:0035319
name: imaginal disc-derived wing hair elongation
namespace: biological_process
def:
  "Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles." [GOC:mtg_sensu, PMID:11832234]


id: GO:0035320
name: imaginal disc-derived wing hair site selection
namespace: biological_process
def:
  "Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally." [GOC:mtg_transport, ISBN:0815340729, PMID:8947551]


id: GO:0035321
name: maintenance of imaginal disc-derived wing hair orientation
namespace: biological_process
def:
  "Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity." [GOC:mtg_sensu, PMID:15501220]


id: GO:0035322
name: mesenchymal cell migration involved in limb bud formation
namespace: biological_process
def:
  "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh]


id: GO:0035325
name: Toll-like receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response." [PMID:19076341]


id: GO:0035326
name: enhancer binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter." [GOC:sart, GOC:txnOH, SO:0000165]


id: GO:0035327
name: transcriptionally active chromatin
namespace: cellular_component
def:
  "The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed." [GOC:sart, PMID:17965872]


id: GO:0035328
name: transcriptionally silent chromatin
namespace: cellular_component
def:
  "The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed." [GOC:sart, PMID:17965872]


id: GO:0035329
name: hippo signaling
namespace: biological_process
def:
  "The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1." [PMID:17318211, PMID:18328423]


id: GO:0035331
name: negative regulation of hippo signaling
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling." [GOC:bf]


id: GO:0035332
name: positive regulation of hippo signaling
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of hippo signaling." [GOC:bf]


id: GO:0035333
name: Notch receptor processing, ligand-dependent
namespace: biological_process
def:
  "The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD)." [GOC:bf, PMID:12651094]


id: GO:0035334
name: Notch receptor processing, ligand-independent
namespace: biological_process
def:
  "The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface." [GOC:bf, PMID:12651094]


id: GO:0035335
name: peptidyl-tyrosine dephosphorylation
namespace: biological_process
def:
  "The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine." [GOC:bf]


id: GO:0035336
name: long-chain fatty-acyl-CoA metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more." [CHEBI:33184, ISBN:0198506732]


id: GO:0035337
name: fatty-acyl-CoA metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group." [ISBN:0198506732]


id: GO:0035338
name: long-chain fatty-acyl-CoA biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more." [CHEBI:33184, ISBN:0198506732]


id: GO:0035339
name: SPOTS complex
namespace: cellular_component
def:
  "A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis." [PMID:20182505]


id: GO:0035340
name: inosine transport
namespace: biological_process
def:
  "The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [CHEBI:17596, PMID:19135251]


id: GO:0035341
name: regulation of inosine transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035342
name: positive regulation of inosine transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035343
name: negative regulation of inosine transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035344
name: hypoxanthine transport
namespace: biological_process
def:
  "The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [CHEBI:17368, GOC:sl]


id: GO:0035345
name: regulation of hypoxanthine transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035346
name: positive regulation of hypoxanthine transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035347
name: negative regulation of hypoxanthine transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035348
name: acetyl-CoA transmembrane transport
namespace: biological_process
def:
  "The process in which acetyl-CoA is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GO:bf]


id: GO:0035349
name: coenzyme A transmembrane transport
namespace: biological_process
def:
  "The process in which coenzyme A is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:bf]


id: GO:0035350
name: FAD transmembrane transport
namespace: biological_process
def:
  "The process in which flavin-adenine dinucleotide (FAD) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form." [GOC:bf, ISBN:0198506732]


id: GO:0035351
name: heme transmembrane transport
namespace: biological_process
def:
  "The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:bf]


id: GO:0035352
name: NAD transmembrane transport
namespace: biological_process
def:
  "The process in which nicotinamide adenine dinucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:bf]


id: GO:0035353
name: nicotinamide mononucleotide transmembrane transport
namespace: biological_process
def:
  "The process in which nicotinamide mononucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP." [GOC:bf, ISBN:0721662544]


id: GO:0035354
name: Toll-like receptor 1-Toll-like receptor 2 protein complex
namespace: cellular_component
def:
  "A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2)." [GOC:add, GOC:signaling, PMID:17889651, PMID:21481769]


id: GO:0035355
name: Toll-like receptor 2-Toll-like receptor 6 protein complex
namespace: cellular_component
def:
  "A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6)." [GOC:add, GOC:signaling, PMID:19931471, PMID:21481769]


id: GO:0035356
name: cellular triglyceride homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment." [GOC:BHF]


id: GO:0035357
name: peroxisome proliferator activated receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes." [GOC:BHF, PMID:18221086]


id: GO:0035358
name: regulation of peroxisome proliferator activated receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf]


id: GO:0035359
name: negative regulation of peroxisome proliferator activated receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf]


id: GO:0035360
name: positive regulation of peroxisome proliferator activated receptor signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf]


id: GO:0035361
name: Cul8-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins." [GOC:krc, PMID:20139071]


id: GO:0035362
name: protein-DNA ISRE complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA." [GOC:amm, PMID:11747630]


id: GO:0035363
name: histone locus body
namespace: cellular_component
def:
  "A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body." [GOC:sart, PMID:16533947, PMID:18927579, PMID:19620235]


id: GO:0035364
name: thymine transport
namespace: biological_process
def:
  "The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO:sl]


id: GO:0035365
name: regulation of thymine transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl]


id: GO:0035366
name: negative regulation of thymine transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl]


id: GO:0035367
name: positive regulation of thymine transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl]


id: GO:0035368
name: selenocysteine insertion sequence binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation." [GOC:imk, PMID:10760958]


id: GO:0035369
name: pre-B cell receptor complex
namespace: cellular_component
def:
  "An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:16464608, PMID:17306522]


id: GO:0035370
name: UBC13-UEV1A complex
namespace: cellular_component
def:
  "A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A)." [GOC:amm, PMID:16129784]


id: GO:0035371
name: microtubule plus-end
namespace: cellular_component
def:
  "The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability." [GOC:bf, GOC:lb, PMID:12700769, PMID:16643273]


id: GO:0035373
name: chondroitin sulfate proteoglycan binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit." [GOC:kmv, ISBN:0198506732]


id: GO:0035374
name: chondroitin sulfate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc)." [GOC:kmv, ISBN:0198506732]


id: GO:0035375
name: zymogen binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis." [ISBN:0198506732]


id: GO:0035376
name: sterol import
namespace: biological_process
def:
  "The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:bf, PMID:19793923]


id: GO:0035378
name: carbon dioxide transmembrane transport
namespace: biological_process
def:
  "A process in which carbon dioxide (CO2) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:yaf]


id: GO:0035380
name: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [CHEBI:27283, GOC:pde]


id: GO:0035381
name: ATP-gated ion channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts." [GOC:bf]


id: GO:0035382
name: sterol transmembrane transport
namespace: biological_process
def:
  "The directed movement of a sterol across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:vw]


id: GO:0035383
name: thioester metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol." [CHEBI:51277, GOC:bf, http://encyclopedia.thefreedictionary.com/Thioester]


id: GO:0035384
name: thioester biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol." [CHEBI:51277, GOC:bf, http://encyclopedia.thefreedictionary.com/Thioester]


id: GO:0035385
name: Roundabout signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling]


id: GO:0035386
name: regulation of Roundabout signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF]


id: GO:0035387
name: negative regulation of Roundabout signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF]


id: GO:0035388
name: positive regulation of Roundabout signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF]


id: GO:0035389
name: establishment of chromatin silencing at silent mating-type cassette
namespace: biological_process
def:
  "The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at silent mating-type loci." [GOC:vw]


id: GO:0035390
name: establishment of chromatin silencing at telomere
namespace: biological_process
def:
  "The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at the telomere." [GOC:vw]


id: GO:0035391
name: maintenance of chromatin silencing at silent mating-type cassette
namespace: biological_process
def:
  "The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci." [GOC:vw]


id: GO:0035392
name: maintenance of chromatin silencing at telomere
namespace: biological_process
def:
  "The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere." [GOC:vw]


id: GO:0035393
name: chemokine (C-X-C motif) ligand 9 production
namespace: biological_process
def:
  "The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add]


id: GO:0035394
name: regulation of chemokine (C-X-C motif) ligand 9 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf]


id: GO:0035395
name: negative regulation of chemokine (C-X-C motif) ligand 9 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf]


id: GO:0035396
name: positive regulation of chemokine (C-X-C motif) ligand 9 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf]


id: GO:0035397
name: helper T cell enhancement of adaptive immune response
namespace: biological_process
def:
  "Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell." [GOC:add]


id: GO:0035398
name: helper T cell enhancement of T cell mediated immune response
namespace: biological_process
def:
  "Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell." [GOC:add]


id: GO:0035399
name: helper T cell enhancement of B cell mediated immune response
namespace: biological_process
def:
  "Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell." [GOC:add]


id: GO:0035400
name: histone tyrosine kinase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf]


id: GO:0035401
name: histone kinase activity (H3-Y41 specific)
namespace: molecular_function
def:
  "The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone." [GOC:bf]


id: GO:0035402
name: histone kinase activity (H3-T11 specific)
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3." [GOC:bf]


id: GO:0035403
name: histone kinase activity (H3-T6 specific)
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3." [GOC:bf]


id: GO:0035407
name: histone H3-T11 phosphorylation
namespace: biological_process
def:
  "The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone." [GOC:bf]


id: GO:0035408
name: histone H3-T6 phosphorylation
namespace: biological_process
def:
  "The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone." [GOC:bf]


id: GO:0035410
name: dihydrotestosterone 17-beta-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH." [GOC:ecd, http://www.brenda-enzymes.org/php/result_flat.php4?ecno=1.1.1.63, PMID:4152755]


id: GO:0035412
name: regulation of catenin import into nucleus
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus." [GOC:BHF]


id: GO:0035413
name: positive regulation of catenin import into nucleus
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus." [GOC:BHF]


id: GO:0035414
name: negative regulation of catenin import into nucleus
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus." [GOC:BHF]


id: GO:0035415
name: obsolete regulation of mitotic prometaphase
namespace: biological_process
def:
  "OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf]


id: GO:0035416
name: obsolete positive regulation of mitotic prometaphase
namespace: biological_process
def:
  "OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf]


id: GO:0035417
name: obsolete negative regulation of mitotic prometaphase
namespace: biological_process
def:
  "OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf]


id: GO:0035418
name: protein localization to synapse
namespace: biological_process
def:
  "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf]


id: GO:0035419
name: activation of MAPK activity involved in innate immune response
namespace: biological_process
def:
  "Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035420
name: MAPK cascade involved in innate immune response
namespace: biological_process
def:
  "A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035421
name: activation of MAPKK activity involved in innate immune response
namespace: biological_process
def:
  "Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035422
name: activation of MAPKKK activity involved in innate immune response
namespace: biological_process
def:
  "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035423
name: inactivation of MAPK activity involved in innate immune response
namespace: biological_process
def:
  "Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035424
name: MAPK import into nucleus involved in innate immune response
namespace: biological_process
def:
  "The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf]


id: GO:0035425
name: autocrine signaling
namespace: biological_process
def:
  "Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type." [GOC:bf, ISBN:3527303782]


id: GO:0035426
name: extracellular matrix-cell signaling
namespace: biological_process
def:
  "Any process that mediates the transfer of information between the extracellular matrix and a cell." [GOC:bf]


id: GO:0035428
name: hexose transmembrane transport
namespace: biological_process
def:
  "The directed movement of hexose across a membrane by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule." [GOC:vw]


id: GO:0035429
name: gluconate transmembrane transport
namespace: biological_process
def:
  "The directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. Gluconate is the aldonic acid derived from glucose." [GOC:vw, ISBN:0198506732]


id: GO:0035430
name: regulation of gluconate transmembrane transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035431
name: negative regulation of gluconate transmembrane transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035432
name: positive regulation of gluconate transmembrane transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035433
name: acetate transmembrane transport
namespace: biological_process
def:
  "The directed movement of acetate across a membrane by means of some agent such as a transporter or pore. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw]


id: GO:0035435
name: phosphate ion transmembrane transport
namespace: biological_process
def:
  "The directed movement of phosphate across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035436
name: triose phosphate transmembrane transport
namespace: biological_process
def:
  "The directed movement of triose phosphate across a membrane by means of some agent such as a transporter or pore. Triose phosphate is any organic three carbon compound phosphate ester." [GOC:bf, ISBN:0198506732]


id: GO:0035437
name: maintenance of protein localization in endoplasmic reticulum
namespace: biological_process
def:
  "Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum." [GOC:bf, GOC:vw]


id: GO:0035438
name: cyclic-di-GMP binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate." [CHEBI:49537, GOC:bf]


id: GO:0035439
name: halimadienyl-diphosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate." [EC:5.5.1.16]


id: GO:0035440
name: tuberculosinol biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria." [CHEBI:50387, MetaCyc:PWY-5935]


id: GO:0035441
name: cell migration involved in vasculogenesis
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh]


id: GO:0035442
name: dipeptide transmembrane transport
namespace: biological_process
def:
  "The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond." [GOC:vw]


id: GO:0035443
name: tripeptide transmembrane transport
namespace: biological_process
def:
  "The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds." [GOC:vw]


id: GO:0035444
name: nickel cation transmembrane transport
namespace: biological_process
def:
  "The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035445
name: borate transmembrane transport
namespace: biological_process
def:
  "The directed movement of borate across a membrane by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals." [CHEBI:22908, GOC:curators]


id: GO:0035446
name: cysteine-glucosaminylinositol ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins." [EC:6.3.1.13, MetaCyc:RXN1G-4, PMID:12033919]


id: GO:0035447
name: mycothiol synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol." [MetaCyc:MONOMER-9684, PMID:12033919]


id: GO:0035448
name: extrinsic component of thylakoid membrane
namespace: cellular_component
def:
  "The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035449
name: extrinsic component of plastid thylakoid membrane
namespace: cellular_component
def:
  "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035450
name: extrinsic component of lumenal side of plastid thylakoid membrane
namespace: cellular_component
def:
  "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035451
name: extrinsic component of stromal side of plastid thylakoid membrane
namespace: cellular_component
def:
  "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035452
name: extrinsic component of plastid membrane
namespace: cellular_component
def:
  "The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035453
name: extrinsic component of plastid inner membrane
namespace: cellular_component
def:
  "The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035454
name: extrinsic component of stromal side of plastid inner membrane
namespace: cellular_component
def:
  "The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos]


id: GO:0035455
name: response to interferon-alpha
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon." [GOC:sl, PMID:11356686]


id: GO:0035456
name: response to interferon-beta
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon." [GOC:sl, PMID:9561374, PR:000008924]


id: GO:0035457
name: cellular response to interferon-alpha
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon." [GOC:sl, PR:000024938]


id: GO:0035458
name: cellular response to interferon-beta
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon." [GOC:sl, PR:000024939]


id: GO:0035459
name: cargo loading into vesicle
namespace: biological_process
def:
  "The formation of a protein complex between the coat proteins and proteins that are going to be transported by a vesicle." [GOC:bf]


id: GO:0035460
name: L-ascorbate 6-phosphate lactonase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate." [PMID:18097099, PMID:20359483]


id: GO:0035461
name: vitamin transmembrane transport
namespace: biological_process
def:
  "The process in which a vitamin is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:bf]


id: GO:0035462
name: determination of left/right asymmetry in diencephalon
namespace: biological_process
def:
  "The establishment of the diencephalon with respect to the left and right halves." [GOC:dgh, PMID:15084459]


id: GO:0035463
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry

def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves." [GOC:dgh, GOC:signaling]


id: GO:0035464
namespace: biological_process
name:
  regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry

def:
  "Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves." [GOC:dgh]


id: GO:0035465
namespace: biological_process
name:
  obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry

def:
  "OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves." [GOC:dgh, PMID:15084459]


id: GO:0035469
name: determination of pancreatic left/right asymmetry
namespace: biological_process
def:
  "Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism." [GOC:dgh, PMID:12702646]


id: GO:0035470
name: positive regulation of vascular wound healing
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:rph]


id: GO:0035471
name: luteinizing hormone signaling pathway involved in ovarian follicle development
namespace: biological_process
def:
  "The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure." [GOC:bf]


id: GO:0035472
name: choriogonadotropin hormone receptor activity
namespace: molecular_function
def:
  "Combining with the choriogonadotropin hormone to initiate a change in cell activity." [GOC:bf, ISBN:0198506732, PMID:1922095]


id: GO:0035474
name: selective angioblast sprouting
namespace: biological_process
def:
  "The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel." [GOC:dgh, PMID:19815777]


id: GO:0035475
name: angioblast cell migration involved in selective angioblast sprouting
namespace: biological_process
def:
  "The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations." [GOC:dgh, PMID:19815777]


id: GO:0035476
name: angioblast cell migration
namespace: biological_process
def:
  "The orderly movement of angioblasts, cells involved in blood vessel morphogenesis." [GOC:dgh, PMID:19815777]


id: GO:0035477
name: regulation of angioblast cell migration involved in selective angioblast sprouting
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting." [GOC:dgh, PMID:19815777]


id: GO:0035478
name: chylomicron binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE." [GOC:BHF, http://www.britannica.com/EBchecked/topic/117461/chylomicron]


id: GO:0035479
name: angioblast cell migration from lateral mesoderm to midline
namespace: biological_process
def:
  "The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature." [GOC:dgh, PMID:11861480]


id: GO:0035480
name: regulation of Notch signaling pathway involved in heart induction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction." [GOC:BHF]


id: GO:0035481
name: positive regulation of Notch signaling pathway involved in heart induction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction." [GOC:BHF]


id: GO:0035482
name: gastric motility
namespace: biological_process
def:
  "The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum." [GOC:cy, ISBN:9781416032458, PMID:16139031]


id: GO:0035483
name: gastric emptying
namespace: biological_process
def:
  "The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum." [GOC:cy, ISBN:9781416032458]


id: GO:0035484
name: adenine/adenine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing an A/A mispair." [GOC:bf, GOC:jh]


id: GO:0035485
name: adenine/guanine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing an A/G mispair." [GOC:bf, GOC:jh]


id: GO:0035486
name: cytosine/cytosine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a C/C mispair." [GOC:bf, GOC:jh]


id: GO:0035487
name: thymine/thymine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a T/T mispair." [GOC:bf, GOC:jh]


id: GO:0035488
name: cytosine/thymine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a C/T mispair." [GOC:bf, GOC:jh]


id: GO:0035489
name: guanine/guanine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a G/G mispair." [GOC:bf, GOC:jh]


id: GO:0035490
name: regulation of leukotriene production involved in inflammatory response
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf]


id: GO:0035491
name: positive regulation of leukotriene production involved in inflammatory response
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf]


id: GO:0035492
name: negative regulation of leukotriene production involved in inflammatory response
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf]


id: GO:0035493
name: SNARE complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb, PMID:10872468]


id: GO:0035494
name: SNARE complex disassembly
namespace: biological_process
def:
  "The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb, PMID:11697877]


id: GO:0035495
name: regulation of SNARE complex disassembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035496
name: lipopolysaccharide-1,5-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide." [EC:2.4.1.-, PMID:11304545]


id: GO:0035497
name: cAMP response element binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP." [PMID:2875459, PMID:2900470]


id: GO:0035498
name: carnosine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine)." [PMID:20097752]


id: GO:0035499
name: carnosine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine)." [EC:6.3.2.11, PMID:20097752]


id: GO:0035500
name: MH2 domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers." [Pfam:PF03166]


id: GO:0035501
name: MH1 domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors." [Pfam:PF03165]


id: GO:0035502
name: metanephric part of ureteric bud development
namespace: biological_process
def:
  "The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros." [GOC:mtg_kidney_jan10]


id: GO:0035503
name: ureter part of ureteric bud development
namespace: biological_process
def:
  "The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter." [GOC:mtg_kidney_jan10]


id: GO:0035504
name: regulation of myosin light chain kinase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators]


id: GO:0035505
name: positive regulation of myosin light chain kinase activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators]


id: GO:0035506
name: negative regulation of myosin light chain kinase activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators]


id: GO:0035507
name: regulation of myosin-light-chain-phosphatase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators]


id: GO:0035508
name: positive regulation of myosin-light-chain-phosphatase activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators]


id: GO:0035509
name: negative regulation of myosin-light-chain-phosphatase activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators]


id: GO:0035511
name: oxidative DNA demethylation
namespace: biological_process
def:
  "Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698]


id: GO:0035512
name: hydrolytic DNA demethylation
namespace: biological_process
def:
  "The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule." [GOC:bf]


id: GO:0035513
name: oxidative RNA demethylation
namespace: biological_process
def:
  "The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698]


id: GO:0035514
name: DNA demethylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule." [GOC:bf]


id: GO:0035515
name: oxidative RNA demethylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698]


id: GO:0035516
name: oxidative DNA demethylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698]


id: GO:0035517
name: PR-DUB complex
namespace: cellular_component
def:
  "A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively." [PMID:20436459]


id: GO:0035519
name: protein K29-linked ubiquitination
namespace: biological_process
def:
  "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation." [PMID:17028573]


id: GO:0035521
name: monoubiquitinated histone deubiquitination
namespace: biological_process
def:
  "The removal of the ubiquitin group from a monoubiquitinated histone protein." [GOC:bf, PMID:20436459]


id: GO:0035522
name: monoubiquitinated histone H2A deubiquitination
namespace: biological_process
def:
  "The removal of the ubiquitin group from a monoubiquitinated histone H2A protein." [GOC:bf, PMID:18226187, PMID:20436459]


id: GO:0035523
name: protein K29-linked deubiquitination
namespace: biological_process
def:
  "A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein." [GOC:bf]


id: GO:0035524
name: proline transmembrane transport
namespace: biological_process
def:
  "The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035526
name: retrograde transport, plasma membrane to Golgi
namespace: biological_process
def:
  "The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles." [GOC:lb, PMID:17488291]


id: GO:0035527
name: 3-hydroxypropionate dehydrogenase (NADP+) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH." [RHEA:26441]


id: GO:0035528
name: UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin." [GOC:bf]


id: GO:0035529
name: NADH pyrophosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+." [MetaCyc:RXN0-4401, PMID:12399474, PMID:20181750]


id: GO:0035530
name: chemokine (C-C motif) ligand 6 production
namespace: biological_process
def:
  "The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, PMID:19812544]


id: GO:0035531
name: regulation of chemokine (C-C motif) ligand 6 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf]


id: GO:0035532
name: negative regulation of chemokine (C-C motif) ligand 6 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf]


id: GO:0035533
name: positive regulation of chemokine (C-C motif) ligand 6 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf]


id: GO:0035535
name: regulation of chemokine (C-C motif) ligand 6 secretion
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf]


id: GO:0035536
name: negative regulation of chemokine (C-C motif) ligand 6 secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf]


id: GO:0035537
name: positive regulation of chemokine (C-C motif) ligand 6 secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf]


id: GO:0035538
name: carbohydrate response element binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes." [GOC:BHF, PMID:20001964]


id: GO:0035539
name: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA." [PMID:17804481, PMID:7782328, PMID:7859359]


id: GO:0035540
name: positive regulation of SNARE complex disassembly
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035541
name: negative regulation of SNARE complex disassembly
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035542
name: regulation of SNARE complex assembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035543
name: positive regulation of SNARE complex assembly
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035544
name: negative regulation of SNARE complex assembly
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb]


id: GO:0035545
name: determination of left/right asymmetry in nervous system
namespace: biological_process
def:
  "The establishment of the nervous system with respect to the left and right halves." [GOC:kmv, PMID:17717195, PMID:19641012]


id: GO:0035547
name: regulation of interferon-beta secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf]


id: GO:0035548
name: negative regulation of interferon-beta secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf]


id: GO:0035549
name: positive regulation of interferon-beta secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf]


id: GO:0035550
name: urease complex
namespace: cellular_component
def:
  "A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide)." [InterPro:IPR008221, PMID:2651866]


id: GO:0035551
name: protein initiator methionine removal involved in protein maturation
namespace: biological_process
def:
  "Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein." [GOC:bf, GOC:hjd, GOC:vw]


id: GO:0035552
name: oxidative single-stranded DNA demethylation
namespace: biological_process
def:
  "Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [GOC:BHF, GOC:rl, PMID:18775698]


id: GO:0035553
name: oxidative single-stranded RNA demethylation
namespace: biological_process
def:
  "Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [GOC:BHF, GOC:rl, PMID:18775698]


id: GO:0035554
name: termination of Roundabout signal transduction
namespace: biological_process
def:
  "The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated." [GOC:BHF, GOC:vk]


id: GO:0035555
name: obsolete initiation of Roundabout signal transduction
namespace: biological_process
def:
  "OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO)." [GOC:vk]


id: GO:0035556
name: intracellular signal transduction
namespace: biological_process
def:
  "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]


id: GO:0035557
name: obsolete intracellular signal transduction involved in cell surface receptor linked signaling
namespace: biological_process
def:
  "OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling, ISBN:3527303782]


id: GO:0035558
name: obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling
namespace: biological_process
def:
  "OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:signaling]


id: GO:0035559
name: obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling
namespace: biological_process
def:
  "OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling]


id: GO:0035560
name: pheophoridase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a." [EC:3.1.1.82, PMID:16228561]


id: GO:0035561
name: regulation of chromatin binding
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130]


id: GO:0035562
name: negative regulation of chromatin binding
namespace: biological_process
def:
  "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130]


id: GO:0035563
name: positive regulation of chromatin binding
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130]


id: GO:0035567
name: non-canonical Wnt signaling pathway
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin." [GOC:signaling]


id: GO:0035569
name: obsolete N-terminal peptidyl-proline trimethylation
namespace: biological_process
def:
  "The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline." [PMID:20668449]


id: GO:0035571
name: N-terminal peptidyl-serine monomethylation
namespace: biological_process
def:
  "The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine." [PMID:20668449]


id: GO:0035572
name: N-terminal peptidyl-serine dimethylation
namespace: biological_process
def:
  "The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine." [PMID:20668449]


id: GO:0035573
name: N-terminal peptidyl-serine trimethylation
namespace: biological_process
def:
  "The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine." [PMID:20668449]


id: GO:0035574
name: histone H4-K20 demethylation
namespace: biological_process
def:
  "The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone." [GOC:sp, PMID:20622853]


id: GO:0035575
name: histone demethylase activity (H4-K20 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein." [EC:1.14.11.27, PMID:20622853]


id: GO:0035576
name: retinoic acid receptor signaling pathway involved in pronephric field specification
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop." [GOC:bf, PMID:16979153, PMID:19909807]


id: GO:0035577
name: azurophil granule membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:bf, PMID:17152095]


id: GO:0035578
name: azurophil granule lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:bf, PMID:17152095]


id: GO:0035579
name: specific granule membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:bf, PMID:7334549]


id: GO:0035580
name: specific granule lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:bf, PMID:7334549]


id: GO:0035581
name: sequestering of extracellular ligand from receptor
namespace: biological_process
def:
  "The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor." [GOC:BHF, GOC:signaling]


id: GO:0035582
name: sequestering of BMP in extracellular matrix
namespace: biological_process
def:
  "Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins." [GOC:BHF, PMID:20855508]


id: GO:0035583
name: sequestering of TGFbeta in extracellular matrix
namespace: biological_process
def:
  "Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins." [GOC:bf, GOC:BHF, GOC:signaling, PMID:12482908, PMID:20855508]


id: GO:0035584
name: calcium-mediated signaling using intracellular calcium source
namespace: biological_process
def:
  "A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response." [GOC:bf, GOC:BHF, PMID:20192754]


id: GO:0035585
name: calcium-mediated signaling using extracellular calcium source
namespace: biological_process
def:
  "A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response." [GOC:bf, GOC:BHF, PMID:20192754]


id: GO:0035586
name: purinergic receptor activity
namespace: molecular_function
def:
  "Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule." [GOC:bf, GOC:BHF, GOC:signaling, PMID:9755289]


id: GO:0035587
name: purinergic receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative to initiate a change in cell activity." [GOC:BHF, PMID:9755289]


id: GO:0035588
name: G-protein coupled purinergic receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:BHF, PMID:9755289]


id: GO:0035589
name: G-protein coupled purinergic nucleotide receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:BHF, PMID:9755289]


id: GO:0035590
name: purinergic nucleotide receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity." [GOC:BHF, PMID:9755289]


id: GO:0035591
name: signaling adaptor activity
namespace: molecular_function
def:
  "The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity." [GOC:bf]


id: GO:0035592
name: establishment of protein localization to extracellular region
namespace: biological_process
def:
  "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF]


id: GO:0035593
namespace: biological_process
name:
  positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region

def:
  "Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region." [GOC:BHF, PMID:19906850]


id: GO:0035594
name: ganglioside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues." [GOC:yaf]


id: GO:0035595
name: N-acetylglucosaminylinositol deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol." [EC:3.5.1.103, GOC:rs]


id: GO:0035596
name: methylthiotransferase activity
namespace: molecular_function
def:
  "Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor." [GOC:jh2, PMID:20472640]


id: GO:0035597
name: N6-isopentenyladenosine methylthiotransferase activity
namespace: molecular_function
def:
  "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A)." [PMID:20472640]


id: GO:0035598
name: N6-threonylcarbomyladenosine methylthiotransferase activity
namespace: molecular_function
def:
  "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A)." [PMID:20472640, PMID:20584901]


id: GO:0035599
name: aspartic acid methylthiotransferase activity
namespace: molecular_function
def:
  "Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid." [PMID:18252828, PMID:8844851, RESID:AA0232]


id: GO:0035600
name: tRNA methylthiolation
namespace: biological_process
def:
  "The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule." [PMID:20472640]


id: GO:0035601
name: protein deacylation
namespace: biological_process
def:
  "The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid." [GOC:se, PMID:12080046]


id: GO:0035602
namespace: biological_process
name:
  fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow

def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow." [GOC:mtg_apoptosis, GOC:yaf]


id: GO:0035603
name: fibroblast growth factor receptor signaling pathway involved in hemopoiesis
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis." [GOC:yaf]


id: GO:0035604
namespace: biological_process
name:
  fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow." [GOC:yaf]


id: GO:0035605
name: peptidyl-cysteine S-nitrosylase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein." [EC:2.6.99.-, GOC:sp, PMID:20972425, PMID:20972426]


id: GO:0035606
name: peptidyl-cysteine S-trans-nitrosylation
namespace: biological_process
def:
  "Transfer of a nitric oxide (NO) group from one cysteine residue to another." [PMID:19854201, PMID:20972425, PMID:20972426]


id: GO:0035607
name: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state." [GOC:yaf]


id: GO:0035608
name: protein deglutamylation
namespace: biological_process
def:
  "The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation." [GOC:sp, PMID:21074048]


id: GO:0035609
name: C-terminal protein deglutamylation
namespace: biological_process
def:
  "The removal of a C-terminal, gene-encoded glutamate residue from a protein." [GOC:sp, PMID:21074048]


id: GO:0035610
name: protein side chain deglutamylation
namespace: biological_process
def:
  "The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation." [GOC:sp, PMID:21074048]


id: GO:0035611
name: protein branching point deglutamylation
namespace: biological_process
def:
  "The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue." [GOC:sp, PMID:21074048]


id: GO:0035612
name: AP-2 adaptor complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)." [GOC:BHF, PMID:12221107, PMID:15728179, PMID:21097499]


id: GO:0035613
name: RNA stem-loop binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop." [GOC:sart, PMID:16568238, PMID:20455544]


id: GO:0035614
name: snRNA stem-loop binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop." [GOC:sart, PMID:16568238, PMID:20455544]


id: GO:0035615
name: clathrin adaptor activity
namespace: molecular_function
def:
  "The binding activity of a molecule that brings together clathrin and one or more other molecules, permitting them to function in a coordinated way." [GOC:BHF, PMID:15728179]


id: GO:0035616
name: histone H2B conserved C-terminal lysine deubiquitination
namespace: biological_process
def:
  "A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals." [GOC:bf, GOC:vw, PMID:15657442]


id: GO:0035617
name: stress granule disassembly
namespace: biological_process
def:
  "The disaggregation of a stress granule into its constituent protein and RNA parts." [GOC:BHF, PMID:19825938]


id: GO:0035618
name: root hair
namespace: cellular_component
def:
  "A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall." [http://www.jstor.org/stable/4354264, PO:0000256]


id: GO:0035620
name: ceramide transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of ceramides into, out of or within a cell, or between cells. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:sart, PMID:14685229]


id: GO:0035621
name: ER to Golgi ceramide transport
namespace: biological_process
def:
  "The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:sart, PMID:14685229]


id: GO:0035622
name: intrahepatic bile duct development
namespace: biological_process
def:
  "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624]


id: GO:0035623
name: renal glucose absorption
namespace: biological_process
def:
  "A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:yaf, PMID:11269503]


id: GO:0035624
name: receptor transactivation
namespace: biological_process
def:
  "The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer." [GOC:al, GOC:bf, GOC:BHF, PMID:16870826, PMID:21063387]


id: GO:0035625
namespace: biological_process
name:
  epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway

def:
  "The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways." [GOC:bf, GOC:BHF, PMID:10622253, PMID:17655843]


id: GO:0035626
name: juvenile hormone mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity." [GOC:bf, GOC:sart]


id: GO:0035627
name: ceramide transport
namespace: biological_process
def:
  "The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:bf, GOC:sart]


id: GO:0035628
name: cystic duct development
namespace: biological_process
def:
  "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct." [PMID:20614624]


id: GO:0035629
name: N-terminal protein amino acid N-linked glycosylation
namespace: biological_process
def:
  "Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein." [GOC:bf, GOC:pr]


id: GO:0035630
name: bone mineralization involved in bone maturation
namespace: biological_process
def:
  "The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state." [GOC:bf, GOC:BHF]


id: GO:0035631
name: CD40 receptor complex
namespace: cellular_component
def:
  "A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules." [GOC:BHF, PMID:20614026, PMID:9221764]


id: GO:0035632
name: mitochondrial prohibitin complex
namespace: cellular_component
def:
  "A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death." [GOC:kmv, PMID:12237468, PMID:21164222]


id: GO:0035633
name: maintenance of blood-brain barrier
namespace: biological_process
def:
  "Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:bf, GOC:sl, PMID:20080302]


id: GO:0035634
name: response to stilbenoid
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones." [CHEBI:26776, GOC:yaf, Wikipedia:Stilbenoid]


id: GO:0035635
name: entry of bacterium into host cell
namespace: biological_process
def:
  "The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, PMID:21187937]


id: GO:0035638
name: signal maturation
namespace: biological_process
def:
  "Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response, and is functional when it can activate a receptor." [GOC:bf, GOC:pde, GOC:signaling]


id: GO:0035639
name: purine ribonucleoside triphosphate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [CHEBI:26398, GOC:BHF, GOC:ebc, ISBN:0198506732]


id: GO:0035640
name: exploration behavior
namespace: biological_process
def:
  "The specific behavior of an organism in response to a novel environment or stimulus." [GOC:BHF, GOC:pr, PMID:11682103, PMID:9767169]


id: GO:0035641
name: locomotory exploration behavior
namespace: biological_process
def:
  "The specific movement from place to place of an organism in response to a novel environment." [GOC:sart, PMID:17151232]


id: GO:0035642
name: histone methyltransferase activity (H3-R17 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3." [GOC:sp, PMID:11341840]


id: GO:0035643
name: L-DOPA receptor activity
namespace: molecular_function
def:
  "Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine." [CHEBI:15765, PMID:18828673, Wikipedia:L-DOPA]


id: GO:0035644
name: phosphoanandamide dephosphorylation
namespace: biological_process
def:
  "The process of removing one or more phosphate groups from a phosphorylated anandamide." [CHEBI:2700, GOC:BHF, PMID:16938887]


id: GO:0035645
name: enteric smooth muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF]


id: GO:0035646
name: endosome to melanosome transport
namespace: biological_process
def:
  "The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle." [PMID:16162817]


id: GO:0035647
name: 3-oxo-delta(4,5)-steroid 5-beta-reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+)." [GOC:kad, MetaCyc:RXN-9726, PMID:19166903]


id: GO:0035648
name: circadian mating behavior
namespace: biological_process
def:
  "The fluctuation in mating behavior that occurs over an approximately 24 hour cycle." [GOC:bf, GOC:dos, PMID:11470898, PMID:17276917]


id: GO:0035649
name: Nrd1 complex
namespace: cellular_component
def:
  "A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p." [GOC:jh, PMID:10655211, PMID:16427013, PMID:21084293]


id: GO:0035650
name: AP-1 adaptor complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C)." [PMID:21097499]


id: GO:0035651
name: AP-3 adaptor complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B)." [PMID:21097499]


id: GO:0035652
name: cargo loading into clathrin-coated vesicle
namespace: biological_process
def:
  "Formation of a protein complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins that are going to be transported by a vesicle." [PMID:16162817]


id: GO:0035653
name: cargo loading into clathrin-coated vesicle, AP-1-mediated
namespace: biological_process
def:
  "Formation of a protein complex between proteins of the AP-1 adaptor complex and proteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking." [PMID:12802059, PMID:16162817]


id: GO:0035654
name: cargo loading into clathrin-coated vesicle, AP-3-mediated
namespace: biological_process
def:
  "Formation of a protein complex between proteins of the AP-3 adaptor complex and proteins that are going to be transported by a clathrin-coated vesicle. In some cases, The AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle." [PMID:12802059, PMID:16162817]


id: GO:0035655
name: interleukin-18-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:BHF, GOC:signaling]


id: GO:0035656
name: kinesin-associated melanosomal adaptor activity
namespace: molecular_function
def:
  "The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes." [PMID:19841138]


id: GO:0035657
name: eRF1 methyltransferase complex
namespace: cellular_component
def:
  "A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p." [GOC:rb, PMID:17008308, PMID:20400505]


id: GO:0035658
name: Mon1-Ccz1 complex
namespace: cellular_component
def:
  "A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p." [GOC:rb, PMID:20797862]


id: GO:0035659
name: Wnt signaling pathway involved in wound healing, spreading of epidermal cells
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis." [GOC:BHF]


id: GO:0035660
name: MyD88-dependent toll-like receptor 4 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18304834, PMID:20385024]


id: GO:0035661
name: MyD88-dependent toll-like receptor 2 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response." [GOC:BHF, PMID:20385024]


id: GO:0035662
name: Toll-like receptor 4 binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18304834]


id: GO:0035663
name: Toll-like receptor 2 binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response." [GOC:BHF]


id: GO:0035664
name: TIRAP-dependent toll-like receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:11526399, PMID:11544529, PMID:12447442]


id: GO:0035665
name: TIRAP-dependent toll-like receptor 4 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:12447441]


id: GO:0035666
name: TRIF-dependent toll-like receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:12855817]


id: GO:0035667
name: TRIF-dependent toll-like receptor 4 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18641322, PMID:20511708]


id: GO:0035668
name: TRAM-dependent toll-like receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:14556004]


id: GO:0035669
name: TRAM-dependent toll-like receptor 4 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:14556004, PMID:18297073]


id: GO:0035670
name: plant-type ovary development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed." [GOC:bf, GOC:tb, ISBN:0879015322]


id: GO:0035671
name: enone reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+." [GOC:kad, PMID:17945329, PMID:19166903]


id: GO:0035672
name: oligopeptide transmembrane transport
namespace: biological_process
def:
  "The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:vw, ISBN:0198506732]


id: GO:0035674
name: tricarboxylic acid transmembrane transport
namespace: biological_process
def:
  "The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035675
name: neuromast hair cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0000856]


id: GO:0035676
name: anterior lateral line neuromast hair cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [ISBN:0125296509, ISBN:0387968377]


id: GO:0035677
name: posterior lateral line neuromast hair cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [ISBN:0125296509]


id: GO:0035678
name: neuromast hair cell morphogenesis
namespace: biological_process
def:
  "The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [CL:0000856]


id: GO:0035679
name: anterior lateral line neuromast hair cell morphogenesis
namespace: biological_process
def:
  "The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [ISBN:0125296509, ISBN:0387968377]


id: GO:0035680
name: posterior lateral line neuromast hair cell morphogenesis
namespace: biological_process
def:
  "The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [ISBN:0125296509]


id: GO:0035681
name: toll-like receptor 15 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to toll-like receptor 15." [GOC:pde]


id: GO:0035682
name: toll-like receptor 21 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to toll-like receptor 21." [GOC:pde]


id: GO:0035683
name: memory T cell extravasation
namespace: biological_process
def:
  "The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive." [CL:0000813, GOC:BHF]


id: GO:0035684
name: helper T cell extravasation
namespace: biological_process
def:
  "The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells." [CL:0000912, GOC:BHF]


id: GO:0035685
name: helper T cell diapedesis
namespace: biological_process
def:
  "The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation." [CL:0000912, GOC:BHF]


id: GO:0035686
name: sperm fibrous sheath
namespace: cellular_component
def:
  "A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat." [GOC:BHF, PMID:20731842, PMID:3282552]


id: GO:0035687
name: T-helper 1 cell extravasation
namespace: biological_process
def:
  "The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:BHF]


id: GO:0035688
name: T-helper 1 cell diapedesis
namespace: biological_process
def:
  "The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:BHF, PMID:10477596]


id: GO:0035689
name: chemokine (C-C motif) ligand 5 signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, PMID:18337562]


id: GO:0035690
name: cellular response to drug
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease." [GOC:sl]


id: GO:0035691
name: macrophage migration inhibitory factor signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling, PMID:12782713, PMID:19413900]


id: GO:0035692
name: macrophage migration inhibitory factor receptor complex
namespace: cellular_component
def:
  "A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins." [GOC:BHF, PMID:12782713, PMID:17045821]


id: GO:0035693
name: NOS2-CD74 complex
namespace: cellular_component
def:
  "A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases." [GOC:BHF, PMID:18003616]


id: GO:0035694
name: mitochondrial protein catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." [GOC:sp, PMID:21264221, PMID:21264228]


id: GO:0035695
name: mitophagy by induced vacuole formation
namespace: biological_process
def:
  "The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes." [GOC:autophagy, GOC:bf, GOC:sp, PMID:21264228]


id: GO:0035696
name: monocyte extravasation
namespace: biological_process
def:
  "The migration of a monocyte from the blood vessels into the surrounding tissue." [CL:0000576, GOC:BHF, PMID:10657654]


id: GO:0035697
name: CD8-positive, alpha-beta T cell extravasation
namespace: biological_process
def:
  "The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue." [CL:0000625, GOC:BHF]


id: GO:0035698
name: CD8-positive, alpha-beta cytotoxic T cell extravasation
namespace: biological_process
def:
  "The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue." [CL:0000794, GOC:BHF]


id: GO:0035699
name: T-helper 17 cell extravasation
namespace: biological_process
def:
  "The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue." [CL:0000899, GOC:BHF]


id: GO:0035700
name: astrocyte chemotaxis
namespace: biological_process
def:
  "The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000127, GOC:BHF, PMID:12271471]


id: GO:0035701
name: hematopoietic stem cell migration
namespace: biological_process
def:
  "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092]


id: GO:0035702
name: monocyte homeostasis
namespace: biological_process
def:
  "The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000576, GOC:BHF, PMID:18832716]


id: GO:0035704
name: helper T cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a helper T cell in response to an external stimulus." [CL:0000912, GOC:BHF]


id: GO:0035705
name: T-helper 17 cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a T-helper 17 cell in response to an external stimulus." [CL:0000899, GOC:BHF]


id: GO:0035706
name: T-helper 1 cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a T-helper 1 cell in response to an external stimulus." [CL:0000545, GOC:BHF]


id: GO:0035707
name: T-helper 2 cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a T-helper 2 cell in response to an external stimulus." [CL:0000546, GOC:BHF]


id: GO:0035708
name: interleukin-4-dependent isotype switching to IgE isotypes
namespace: biological_process
def:
  "The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4)." [GOC:BHF, PMID:12496423]


id: GO:0035709
name: memory T cell activation
namespace: biological_process
def:
  "The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000813, GOC:BHF]


id: GO:0035710
name: CD4-positive, alpha-beta T cell activation
namespace: biological_process
def:
  "The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000624, GOC:BHF]


id: GO:0035711
name: T-helper 1 cell activation
namespace: biological_process
def:
  "The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000545, GOC:BHF]


id: GO:0035712
name: T-helper 2 cell activation
namespace: biological_process
def:
  "The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000546, GOC:BHF]


id: GO:0035713
name: response to nitrogen dioxide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus." [CHEBI:33101, GOC:BHF]


id: GO:0035714
name: cellular response to nitrogen dioxide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus." [CHEBI:33101, GOC:BHF]


id: GO:0035718
name: macrophage migration inhibitory factor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor." [GOC:BHF, PMID:19601712]


id: GO:0035720
name: intraciliary anterograde transport
namespace: biological_process
def:
  "The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins." [GOC:BHF, GOC:cilia, PMID:17895364]


id: GO:0035721
name: intraciliary retrograde transport
namespace: biological_process
def:
  "The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins." [GOC:BHF, GOC:cilia]


id: GO:0035722
name: interleukin-12-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling]


id: GO:0035723
name: interleukin-15-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling]


id: GO:0035724
name: CD24 biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation." [GOC:BHF]


id: GO:0035725
name: sodium ion transmembrane transport
namespace: biological_process
def:
  "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw]


id: GO:0035726
name: common myeloid progenitor cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage." [CL:0000049, GOC:BHF]


id: GO:0035727
name: lysophosphatidic acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G-protein-coupled receptors." [CHEBI:52288]


id: GO:0035728
name: response to hepatocyte growth factor
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus." [GOC:bf]


id: GO:0035729
name: cellular response to hepatocyte growth factor stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus." [GOC:bf]


id: GO:0035730
name: S-nitrosoglutathione binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems." [CHEBI:50091, GOC:BHF]


id: GO:0035731
name: dinitrosyl-iron complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO." [GOC:BHF, PMID:10534443]


id: GO:0035732
name: nitric oxide storage
namespace: biological_process
def:
  "The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins." [GOC:BHF, PMID:12871945]


id: GO:0035733
name: hepatic stellate cell activation
namespace: biological_process
def:
  "A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor." [CL:0000632, GOC:bf]


id: GO:0035735
name: intraciliary transport involved in cilium morphogenesis
namespace: biological_process
def:
  "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium morphogenesis." [GOC:bf, GOC:cilia]


id: GO:0035736
name: cell proliferation involved in compound eye morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart]


id: GO:0035737
name: injection of substance in to other organism
namespace: biological_process
def:
  "The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes." [GOC:pamgo_curators]


id: GO:0035738
name: envenomation resulting in modification of morphology or physiology of other organism
namespace: biological_process
def:
  "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism." [GOC:pamgo_curators]


id: GO:0035739
name: CD4-positive, alpha-beta T cell proliferation
namespace: biological_process
def:
  "The expansion of a CD4-positive, alpha-beta T cell population by cell division." [CL:0000624, GOC:BHF]


id: GO:0035740
name: CD8-positive, alpha-beta T cell proliferation
namespace: biological_process
def:
  "The expansion of a CD8-positive, alpha-beta T cell population by cell division." [CL:0000625, GOC:BHF]


id: GO:0035741
name: activated CD4-positive, alpha-beta T cell proliferation
namespace: biological_process
def:
  "The expansion of an activated CD4-positive, alpha-beta T cell population by cell division." [CL:0000896, GOC:BHF]


id: GO:0035742
name: activated CD8-positive, alpha-beta T cell proliferation
namespace: biological_process
def:
  "The expansion of an activated CD8-positive, alpha-beta T cell population by cell division." [CL:0000906, GOC:BHF]


id: GO:0035743
name: CD4-positive, alpha-beta T cell cytokine production
namespace: biological_process
def:
  "Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell." [CL:0000624, GOC:BHF]


id: GO:0035746
name: granzyme A production
namespace: biological_process
def:
  "The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF]


id: GO:0035747
name: natural killer cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000623, GOC:BHF]


id: GO:0035750
name: protein localization to myelin sheath abaxonal region
namespace: biological_process
def:
  "Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon." [GOC:BHF, PMID:20237282]


id: GO:0035751
name: regulation of lysosomal lumen pH
namespace: biological_process
def:
  "Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion." [GOC:rph]


id: GO:0035752
name: lysosomal lumen pH elevation
namespace: biological_process
def:
  "Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion." [GOC:bf, GOC:rph]


id: GO:0035753
name: maintenance of DNA trinucleotide repeats
namespace: biological_process
def:
  "Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs." [GOC:rb, PMID:21347277, SO:0000291]


id: GO:0035754
name: B cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000236, GOC:BHF]


id: GO:0035755
name: cardiolipin hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA)." [CHEBI:28494, GOC:sp, PMID:17028579, PMID:21397848]


id: GO:0035756
name: transepithelial migration of symbiont in host
namespace: biological_process
def:
  "The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, PMID:10639460]


id: GO:0035759
name: mesangial cell-matrix adhesion
namespace: biological_process
def:
  "The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney." [CL:0000650, GOC:BHF, PMID:15569314]


id: GO:0035760
name: cytoplasmic polyadenylation-dependent rRNA catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate." [PMID:20368444]


id: GO:0035761
name: dorsal motor nucleus of vagus nerve maturation
namespace: biological_process
def:
  "A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state." [GOC:dgh]


id: GO:0035762
name: dorsal motor nucleus of vagus nerve morphogenesis
namespace: biological_process
def:
  "The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dgh]


id: GO:0035763
name: dorsal motor nucleus of vagus nerve structural organization
namespace: biological_process
def:
  "The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh]


id: GO:0035764
name: dorsal motor nucleus of vagus nerve formation
namespace: biological_process
def:
  "The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dgh]


id: GO:0035765
name: motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation
namespace: biological_process
def:
  "The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve." [GOC:dgh, PMID:21262462]


id: GO:0035766
name: cell chemotaxis to fibroblast growth factor
namespace: biological_process
def:
  "The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF)." [GOC:BHF]


id: GO:0035767
name: endothelial cell chemotaxis
namespace: biological_process
def:
  "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000115, GOC:BHF]


id: GO:0035768
name: endothelial cell chemotaxis to fibroblast growth factor
namespace: biological_process
def:
  "The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF)." [CL:0000115, GOC:BHF]


id: GO:0035769
name: B cell chemotaxis across high endothelial venule
namespace: biological_process
def:
  "The movement of a B cell to cross a high endothelial venule in response to an external stimulus." [CL:0000236, GOC:BHF]


id: GO:0035770
name: ribonucleoprotein granule
namespace: cellular_component
def:
  "A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions." [GOC:go_curators, GOC:sp, PMID:16520386, PMID:20368989, PMID:21436445]


id: GO:0035771
name: interleukin-4-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling]


id: GO:0035772
name: interleukin-13-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling]


id: GO:0035773
name: insulin secretion involved in cellular response to glucose stimulus
namespace: biological_process
def:
  "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus." [GOC:bf, GOC:yaf, PMID:8492079]


id: GO:0035774
name: positive regulation of insulin secretion involved in cellular response to glucose stimulus
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:bf, GOC:yaf]


id: GO:0035775
name: pronephric glomerulus morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069]


id: GO:0035776
name: pronephric proximal tubule development
namespace: biological_process
def:
  "The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069]


id: GO:0035777
name: pronephric distal tubule development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069]


id: GO:0035778
name: pronephric nephron tubule epithelial cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069]


id: GO:0035779
name: angioblast cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf]


id: GO:0035780
name: CD80 biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival." [GOC:BHF, GOC:ebc]


id: GO:0035781
name: CD86 biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival." [GOC:BHF, GOC:ebc]


id: GO:0035782
name: mature natural killer cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules." [CL:0000824, GOC:BHF]


id: GO:0035783
name: CD4-positive, alpha-beta T cell costimulation
namespace: biological_process
def:
  "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation." [CL:0000624, GOC:BHF, GOC:pr]


id: GO:0035784
name: nickel cation homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell." [GOC:kmv]


id: GO:0035785
name: cellular nickel ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell." [GOC:kmv]


id: GO:0035786
name: protein complex oligomerization
namespace: biological_process
def:
  "The association of two or more multisubunit protein complexes to form dimers or other multimers of a protein complex." [GOC:bf, GOC:mcc, PMID:18293929]


id: GO:0035787
name: cell migration involved in kidney development
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]


id: GO:0035788
name: cell migration involved in metanephros development
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]


id: GO:0035789
name: metanephric mesenchymal cell migration
namespace: biological_process
def:
  "The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:10734101, PMID:19019919]


id: GO:0035790
name: platelet-derived growth factor receptor-alpha signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:yaf, PMID:10372961, PR:000002030]


id: GO:0035791
name: platelet-derived growth factor receptor-beta signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:signaling, GOC:yaf, PMID:10372961, PR:000002035]


id: GO:0035792
name: other organism postsynaptic membrane
namespace: cellular_component
def:
  "A postsynaptic membrane that is part of another organism, i.e. a secondary organism with which the first organism is interacting. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane." [GOC:ecd]


id: GO:0035793
namespace: biological_process
name:
  positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

def:
  "Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:10734101]


id: GO:0035794
name: positive regulation of mitochondrial membrane permeability
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane." [GOC:bf, PMID:12546810]


id: GO:0035795
name: negative regulation of mitochondrial membrane permeability
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane." [PMID:10781072]


id: GO:0035796
name: ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
namespace: cellular_component
def:
  "A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [PMID:18931129, PMID:20972419, PMID:21135102]


id: GO:0035797
name: tellurite methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride)." [CHEBI:30477, GOC:bf, GOC:kad, PMID:11053398, PMID:21244361]


id: GO:0035798
name: 2-alkenal reductase (NADP+) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+." [GOC:bf, GOC:kad, PMID:16299173]


id: GO:0035799
name: ureter maturation
namespace: biological_process
def:
  "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463]


id: GO:0035800
name: deubiquitinase activator activity
namespace: molecular_function
def:
  "Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences." [GOC:sart, ISBN:0120793709]


id: GO:0035801
name: adrenal cortex development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens)." [PMID:12185666, PMID:21115154, Wikipedia:Adrenal_cortex]


id: GO:0035802
name: adrenal cortex formation
namespace: biological_process
def:
  "The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate)." [PMID:12185666, PMID:21115154]


id: GO:0035803
name: egg coat formation
namespace: biological_process
def:
  "Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [GOC:bf, GOC:sart, GOC:yaf, PMID:16944418, PMID:17163408]


id: GO:0035804
name: structural constituent of egg coat
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408]


id: GO:0035805
name: egg coat
namespace: cellular_component
def:
  "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408]


id: GO:0035806
name: modulation of blood coagulation in other organism
namespace: biological_process
def:
  "Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:bf, GOC:fj]


id: GO:0035807
name: positive regulation of blood coagulation in other organism
namespace: biological_process
def:
  "Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:bf, GOC:fj, PMID:12362232]


id: GO:0035808
name: meiotic recombination initiation complex
namespace: cellular_component
def:
  "A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins." [GOC:vw, PMID:12897161, PMID:20364342, PMID:21429938]


id: GO:0035809
name: regulation of urine volume
namespace: biological_process
def:
  "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035810
name: positive regulation of urine volume
namespace: biological_process
def:
  "Any process that increases the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035811
name: negative regulation of urine volume
namespace: biological_process
def:
  "Any process that decreases the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035813
name: regulation of renal sodium excretion
namespace: biological_process
def:
  "Any process that modulates the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035814
name: negative regulation of renal sodium excretion
namespace: biological_process
def:
  "Any process that decreases the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035815
name: positive regulation of renal sodium excretion
namespace: biological_process
def:
  "Any process that increases the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035816
name: renal water absorption involved in negative regulation of urine volume
namespace: biological_process
def:
  "Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035817
name: renal sodium ion absorption involved in negative regulation of renal sodium excretion
namespace: biological_process
def:
  "Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035818
name: positive regulation of urine volume by pressure natriuresis
namespace: biological_process
def:
  "An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035819
name: positive regulation of renal sodium excretion by pressure natriuresis
namespace: biological_process
def:
  "An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035820
name: negative regulation of renal sodium excretion by angiotensin
namespace: biological_process
def:
  "The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf]


id: GO:0035821
name: modification of morphology or physiology of other organism
namespace: biological_process
def:
  "The process in which an organism effects a change in the structure or processes of a second organism." [GOC:bf]


id: GO:0035822
name: gene conversion
namespace: biological_process
def:
  "A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor." [GOC:mah, PMID:17846636]


id: GO:0035823
name: short tract gene conversion
namespace: biological_process
def:
  "A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor." [GOC:mah, PMID:16954385]


id: GO:0035824
name: long tract gene conversion
namespace: biological_process
def:
  "A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor." [GOC:mah, PMID:16954385]


id: GO:0035825
name: reciprocal DNA recombination
namespace: biological_process
def:
  "A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules." [GOC:mah, PMID:11139492, PMID:17304215]


id: GO:0035826
name: rubidium ion transport
namespace: biological_process
def:
  "The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [CHEBI:49847, GOC:yaf]


id: GO:0035827
name: rubidium ion transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other." [CHEBI:49847, GOC:yaf]


id: GO:0035829
name: renal rubidium ion absorption
namespace: biological_process
def:
  "A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [CHEBI:49847, GOC:yaf]


id: GO:0035830
name: palmatine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants." [CHEBI:16096, GOC:yaf]


id: GO:0035831
name: palmatine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants." [CHEBI:16096, GOC:yaf]


id: GO:0035832
name: berbamunine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid." [CHEBI:16777, GOC:yaf]


id: GO:0035833
name: berbamunine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid." [CHEBI:16777, GOC:yaf]


id: GO:0035834
name: indole alkaloid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [CHEBI:38958, GOC:yaf]


id: GO:0035835
name: indole alkaloid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [CHEBI:38958, GOC:yaf]


id: GO:0035836
name: ergot alkaloid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid." [CHEBI:23943, GOC:yaf]


id: GO:0035837
name: ergot alkaloid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of an ergot alkaloid." [CHEBI:23943, GOC:yaf]


id: GO:0035838
name: growing cell tip
namespace: cellular_component
def:
  "The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs." [GOC:mah]


id: GO:0035839
name: non-growing cell tip
namespace: cellular_component
def:
  "A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures." [GOC:expert_jd, GOC:mah]


id: GO:0035840
name: old growing cell tip
namespace: cellular_component
def:
  "A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures." [GOC:expert_jd, GOC:mah]


id: GO:0035841
name: new growing cell tip
namespace: cellular_component
def:
  "A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth." [GOC:expert_jd, GOC:mah, PMID:19431238]


id: GO:0035842
name: old cell tip after activation of bipolar cell growth
namespace: cellular_component
def:
  "A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures." [GOC:expert_jd, GOC:mah]


id: GO:0035843
name: endonuclear canal
namespace: cellular_component
def:
  "A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope." [GOC:bf, PMID:18359585]


id: GO:0035844
name: cloaca development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089]


id: GO:0035845
name: photoreceptor cell outer segment organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials." [ISBN:0824072820, PMID:14507858]


id: GO:0035846
name: oviduct epithelium development
namespace: biological_process
def:
  "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct]


id: GO:0035847
name: uterine epithelium development
namespace: biological_process
def:
  "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf]


id: GO:0035848
name: oviduct morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct]


id: GO:0035849
name: nephric duct elongation
namespace: biological_process
def:
  "The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236]


id: GO:0035850
name: epithelial cell differentiation involved in kidney development
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236]


id: GO:0035851
name: Krueppel-associated box domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors." [InterPro:IPR001909]


id: GO:0035852
name: horizontal cell localization
namespace: biological_process
def:
  "Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina." [CL:0000745, GOC:bf, GOC:yaf, PMID:18094249]


id: GO:0035853
name: chromosome passenger complex localization to spindle midzone
namespace: biological_process
def:
  "A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:mah, GOC:vw, PMID:15296749]


id: GO:0035854
name: eosinophil fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin." [CL:0000771, GOC:BHF, GOC:vk]


id: GO:0035855
name: megakaryocyte development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk]


id: GO:0035857
name: eosinophil fate specification
namespace: biological_process
def:
  "The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [CL:0000771, GOC:BHF, GOC:vk]


id: GO:0035858
name: eosinophil fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed." [CL:0000771, GOC:BHF, GOC:vk]


id: GO:0035859
name: Seh1-associated complex
namespace: cellular_component
def:
  "A protein complex that associates dynamically with the vacuolar membrane, and is proposed to have a role in membrane-associated trafficking or regulatory processes. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p." [GOC:jh, PMID:21454883, PMID:23974112]


id: GO:0035860
name: glial cell-derived neurotrophic factor receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands." [GOC:yaf, PMID:12953054]


id: GO:0035861
name: site of double-strand break
namespace: cellular_component
def:
  "A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix." [GOC:bf, GOC:mah, GOC:vw, PMID:20096808, PMID:21035408]


id: GO:0035862
name: dITP metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position." [CHEBI:28807, GOC:bf]


id: GO:0035863
name: dITP catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position." [CHEBI:28807, GOC:dgf]


id: GO:0035864
name: response to potassium ion
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus." [GOC:yaf]


id: GO:0035865
name: cellular response to potassium ion
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus." [GOC:yaf]


id: GO:0035866
name: alphav-beta3 integrin-PKCalpha complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha." [GOC:BHF, GOC:ebc, PMID:16014375]


id: GO:0035867
name: alphav-beta3 integrin-IGF-1-IGF1R complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits." [GOC:BHF, GOC:ebc, PMID:19578119]


id: GO:0035868
name: alphav-beta3 integrin-HMGB1 complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein." [GOC:BHF, GOC:ebc, PMID:20826760]


id: GO:0035869
name: ciliary transition zone
namespace: cellular_component
def:
  "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition." [GOC:cilia, GOC:kmv, PMID:21422230]


id: GO:0035870
name: dITP diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dITP + H2O = dIMP + diphosphate." [EC:3.6.1.-, GOC:dgf, PMID:21548881, RHEA:28342]


id: GO:0035871
name: protein K11-linked deubiquitination
namespace: biological_process
def:
  "A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein." [GOC:sp, PMID:21596315]


id: GO:0035872
name: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
namespace: biological_process
def:
  "A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process." [GOC:sj, PMID:18280719, Reactome:168643]


id: GO:0035873
name: lactate transmembrane transport
namespace: biological_process
def:
  "The directed movement of lactate across a membrane by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:mcc, ISBN:0198506732]


id: GO:0035874
name: cellular response to copper ion starvation
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions." [GOC:vw, PMID:16467469]


id: GO:0035875
name: maintenance of meiotic sister chromatid cohesion, centromeric
namespace: biological_process
def:
  "The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:vw, PMID:1708436]


id: GO:0035876
name: maintenance of meiotic sister chromatid cohesion, arms
namespace: biological_process
def:
  "The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:vw, PMID:1708436]


id: GO:0035877
name: death effector domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD)." [GOC:ecd, InterPro:IPR001875]


id: GO:0035878
name: nail development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it." [GOC:bf, ISBN:0323025781, UBERON:0001705, Wikipedia:Nail_(anatomy)]


id: GO:0035880
name: embryonic nail plate morphogenesis
namespace: biological_process
def:
  "The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits." [GOC:BHF, GOC:vk, ISBN:0323025781, PMID:11369996, UBERON:0008198, Wikipedia:Nail_(anatomy)]


id: GO:0035881
name: amacrine cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons." [CL:0000561, GOC:bf]


id: GO:0035882
name: defecation rhythm
namespace: biological_process
def:
  "The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated." [GOC:bf, GOC:kmv, PMID:7479775, PMID:8158250, PMID:9066270]


id: GO:0035883
name: enteroendocrine cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf]


id: GO:0035884
name: arabinan biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues." [CHEBI:22590, GOC:rs, ISBN:0198506732]


id: GO:0035885
name: exochitinase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain." [EC:3.2.1.-, GOC:bf, GOC:kah, GOC:pde, PMID:11468293, PMID:16298970, PMID:21390509]


id: GO:0035886
name: vascular smooth muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954]


id: GO:0035887
name: aortic smooth muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl]


id: GO:0035888
name: isoguanine deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: isoguanine + H2O = xanthine + NH3." [EC:3.5.4.-, GOC:imk, PMID:21604715]


id: GO:0035889
name: otolith tethering
namespace: biological_process
def:
  "The attachment of a developing otolith to the kinocilia of tether cells in the inner ear." [GOC:dgh, PMID:14499652]


id: GO:0035890
name: exit from host
namespace: biological_process
def:
  "The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf]


id: GO:0035891
name: exit from host cell
namespace: biological_process
def:
  "The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:rs, PMID:19325115]


id: GO:0035892
name: modulation of platelet aggregation in other organism
namespace: biological_process
def:
  "Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:bf, GOC:fj, PMID:15922770]


id: GO:0035893
name: negative regulation of platelet aggregation in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism." [GOC:bf, GOC:fj, PMID:15922770]


id: GO:0035894
name: positive regulation of platelet aggregation in other organism
namespace: biological_process
def:
  "Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism." [GOC:bf, GOC:fj, PMID:11453648, PMID:18804547]


id: GO:0035895
name: modulation of mast cell degranulation in other organism
namespace: biological_process
def:
  "Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell." [GOC:bf, GOC:fj, PMID:21549739]


id: GO:0035896
name: positive regulation of mast cell degranulation in other organism
namespace: biological_process
def:
  "Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism." [GOC:bf, GOC:fj]


id: GO:0035897
name: proteolysis in other organism
namespace: biological_process
def:
  "The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds." [GOC:bf, GOC:fj, PMID:15922779]


id: GO:0035898
name: parathyroid hormone secretion
namespace: biological_process
def:
  "The regulated release of parathyroid hormone into the circulatory system." [GOC:cjm, PMID:12171519, PMID:21164021, PR:000013429]


id: GO:0035899
name: negative regulation of blood coagulation in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:fj]


id: GO:0035900
name: response to isolation stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species." [GOC:bf, PMID:20203532]


id: GO:0035901
name: cellular response to isolation stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species." [GOC:bf, PMID:20203532]


id: GO:0035902
name: response to immobilization stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile." [GOC:bf, PMID:17683801, PMID:19893991]


id: GO:0035903
name: cellular response to immobilization stress
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile." [GOC:bf, PMID:17683801, PMID:19893991]


id: GO:0035904
name: aorta development
namespace: biological_process
def:
  "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]


id: GO:0035905
name: ascending aorta development
namespace: biological_process
def:
  "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta]


id: GO:0035906
name: descending aorta development
namespace: biological_process
def:
  "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta]


id: GO:0035907
name: dorsal aorta development
namespace: biological_process
def:
  "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]


id: GO:0035908
name: ventral aorta development
namespace: biological_process
def:
  "The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0003085, Wikipedia:Aorta, ZFA:0000604]


id: GO:0035909
name: aorta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]


id: GO:0035910
name: ascending aorta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta]


id: GO:0035911
name: descending aorta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta]


id: GO:0035912
name: dorsal aorta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]


id: GO:0035913
name: ventral aorta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0003085, Wikipedia:Aorta, ZFA:0000604]


id: GO:0035914
name: skeletal muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk]


id: GO:0035915
name: pore formation in membrane of other organism
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism." [GOC:bf, GOC:fj, PMID:21549739]


id: GO:0035916
name: modulation of calcium channel activity in other organism
namespace: biological_process
def:
  "Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism." [GOC:bf, GOC:fj, PMID:20920515]


id: GO:0035917
name: negative regulation of calcium channel activity in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism." [GOC:bf, GOC:fj, PMID:20920515]


id: GO:0035918
name: negative regulation of voltage-gated calcium channel activity in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515]


id: GO:0035919
name: negative regulation of low voltage-gated calcium channel activity in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515]


id: GO:0035920
name: negative regulation of high voltage-gated calcium channel activity in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515]


id: GO:0035921
name: desmosome disassembly
namespace: biological_process
def:
  "The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm." [GOC:BHF, GOC:vk, ISBN:0198506732, PMID:9182671]


id: GO:0035922
name: foramen ovale closure
namespace: biological_process
def:
  "The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow." [GOC:BHF, GOC:vk, PMID:19762328, UBERON:0004754, Wikipedia:Foramen_ovale_(heart)]


id: GO:0035924
name: cellular response to vascular endothelial growth factor stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus." [GOC:BHF, GOC:rl, PMID:18440775]


id: GO:0035925
name: mRNA 3'-UTR AU-rich region binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule." [GOC:vw]


id: GO:0035928
name: rRNA import into mitochondrion
namespace: biological_process
def:
  "The directed movement of rRNA, ribosomal ribonucleic acid, from the cytoplasm into a mitochondrion." [GOC:ans, PMID:20691904]


id: GO:0035929
name: steroid hormone secretion
namespace: biological_process
def:
  "The regulated release of any steroid that acts as a hormone into the circulatory system." [CHEBI:26764, GOC:sl]


id: GO:0035930
name: corticosteroid hormone secretion
namespace: biological_process
def:
  "The regulated release of any corticosteroid hormone into the circulatory system." [CHEBI:3669, GOC:sl]


id: GO:0035931
name: mineralocorticoid secretion
namespace: biological_process
def:
  "The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." [CHEBI:25354, GOC:sl]


id: GO:0035932
name: aldosterone secretion
namespace: biological_process
def:
  "The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney." [CHEBI:27584, GOC:sl]


id: GO:0035933
name: glucocorticoid secretion
namespace: biological_process
def:
  "The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." [CHEBI:24261, GOC:sl]


id: GO:0035934
name: corticosterone secretion
namespace: biological_process
def:
  "The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands." [CHEBI:16827, GOC:sl]


id: GO:0035935
name: androgen secretion
namespace: biological_process
def:
  "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [CHEBI:50113, GOC:sl]


id: GO:0035936
name: testosterone secretion
namespace: biological_process
def:
  "The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5." [CHEBI:17347, GOC:sl, PMID:12606499]


id: GO:0035937
name: estrogen secretion
namespace: biological_process
def:
  "The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals." [CHEBI:50114, GOC:sl]


id: GO:0035938
name: estradiol secretion
namespace: biological_process
def:
  "The regulated release of estradiol into the circulatory system." [CHEBI:23965, GOC:sl, PMID:21632818]


id: GO:0035939
name: microsatellite binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem." [GOC:yaf, PMID:21290414, SO:0000289]


id: GO:0035940
name: negative regulation of peptidase activity in other organism
namespace: biological_process
def:
  "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism." [GOC:klp, PMID:10595640]


id: GO:0035941
name: androstenedione secretion
namespace: biological_process
def:
  "The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system." [CHEBI:16422, GOC:sl]


id: GO:0035942
name: dehydroepiandrosterone secretion
namespace: biological_process
def:
  "The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system." [CHEBI:28689, GOC:sl]


id: GO:0035944
name: perforin production
namespace: biological_process
def:
  "The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv, PR:000003466]


id: GO:0035945
name: mitochondrial ncRNA surveillance
namespace: biological_process
def:
  "The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion." [GOC:ans, PMID:19864255]


id: GO:0035946
name: mitochondrial mRNA surveillance
namespace: biological_process
def:
  "The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion." [GOC:ans, PMID:19864255]


id: GO:0035947
name: regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338]


id: GO:0035948
namespace: biological_process
name:
  positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17875938]


id: GO:0035949
namespace: biological_process
name:
  positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17875938]


id: GO:0035950
name: regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992]


id: GO:0035951
namespace: biological_process
name:
  positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf]


id: GO:0035952
namespace: biological_process
name:
  negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter

def:
  "Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992]


id: GO:0035953
name: regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992]


id: GO:0035954
namespace: biological_process
name:
  positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf]


id: GO:0035955
namespace: biological_process
name:
  negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter

def:
  "Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:10850718, PMID:17005992, PMID:9427760]


id: GO:0035956
namespace: biological_process
name:
  regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter

def:
  "Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:9342405]


id: GO:0035957
namespace: biological_process
name:
  positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf]


id: GO:0035958
name: regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338]


id: GO:0035959
namespace: biological_process
name:
  positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338]


id: GO:0035960
namespace: biological_process
name:
  regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter

def:
  "Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229, PMID:16055745]


id: GO:0035961
namespace: biological_process
name:
  positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229]


id: GO:0035962
name: response to interleukin-13
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus." [GOC:sjw, PMID:20100461]


id: GO:0035963
name: cellular response to interleukin-13
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus." [GOC:sjw, PMID:20100461]


id: GO:0035964
name: COPI-coated vesicle budding
namespace: biological_process
def:
  "The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle." [GOC:br, PMID:10052452, PMID:17041781]


id: GO:0035965
name: cardiolipin acyl-chain remodeling
namespace: biological_process
def:
  "Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids." [GOC:bf, GOC:rb, PMID:19244244]


id: GO:0035966
name: response to topologically incorrect protein
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." [GOC:bf]


id: GO:0035967
name: cellular response to topologically incorrect protein
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." [GOC:bf]


id: GO:0035968
name: regulation of sterol import by regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:12077145]


id: GO:0035969
namespace: biological_process
name:
  positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229]


id: GO:0035970
name: peptidyl-threonine dephosphorylation
namespace: biological_process
def:
  "The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine." [GOC:bf]


id: GO:0035971
name: peptidyl-histidine dephosphorylation
namespace: biological_process
def:
  "The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine." [GOC:BHF, GOC:vk, PMID:12383260]


id: GO:0035973
name: aggrephagy
namespace: biological_process
def:
  "Selective degradation of protein aggregates by macroautophagy." [GOC:autophagy, GOC:kmv, PMID:18508269, PMID:25062811]


id: GO:0035974
name: meiotic spindle pole body
namespace: cellular_component
def:
  "The microtubule organizing center on a spindle that forms as part of meiosis; functionally homologous to the animal cell centrosome." [GOC:vw, PMID:21775631]


id: GO:0035975
name: carbamoyl phosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [CHEBI:17672, GOC:yaf, UniPathway:UPA00996]


id: GO:0035976
name: AP1 complex
namespace: cellular_component
def:
  "A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes." [GOC:bf, GOC:BHF, GOC:rl, PMID:20060892, PMID:9069263, Wikipedia:AP-1_transcription_factor]


id: GO:0035977
name: protein deglycosylation involved in glycoprotein catabolic process
namespace: biological_process
def:
  "The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein." [GOC:bf, GOC:vw]


id: GO:0035978
name: histone H2A-S139 phosphorylation
namespace: biological_process
def:
  "The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone." [GOC:yaf, PMID:16061642]


id: GO:0035979
name: histone kinase activity (H2A-S139 specific)
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A." [GOC:yaf, PMID:16061642]


id: GO:0035980
name: obsolete invasive growth in response to nitrogen limitation
namespace: biological_process
def:
  "OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen." [GOC:vw]


id: GO:0035981
name: tongue muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell." [CL:0002673, GOC:yaf, PMID:3393851]


id: GO:0035982
name: obsolete age-dependent behavioral decline
namespace: biological_process
def:
  "OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory." [GOC:kmv, PMID:20523893]


