# go

id: GO:0031080
name: nuclear pore outer ring
namespace: cellular_component
def:
  "A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates)." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078]


id: GO:0031081
name: nuclear pore distribution
namespace: biological_process
def:
  "Any process that establishes the spatial arrangement of nuclear pores within the nuclear envelope." [GOC:mah]


id: GO:0031082
name: BLOC complex
namespace: cellular_component
def:
  "Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex." [PMID:15102850, PMID:15261680]


id: GO:0031083
name: BLOC-1 complex
namespace: cellular_component
def:
  "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins." [PMID:15102850]


id: GO:0031084
name: BLOC-2 complex
namespace: cellular_component
def:
  "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru." [PMID:12548288, PMID:14718540, PMID:15031569]


id: GO:0031085
name: BLOC-3 complex
namespace: cellular_component
def:
  "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins." [PMID:12756248]


id: GO:0031086
name: nuclear-transcribed mRNA catabolic process, deadenylation-independent decay
namespace: biological_process
def:
  "A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability." [GOC:krc, PMID:15225542, PMID:15225544]


id: GO:0031087
name: deadenylation-independent decapping of nuclear-transcribed mRNA
namespace: biological_process
def:
  "Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening." [GOC:krc, PMID:15225542, PMID:15225544]


id: GO:0031090
name: organelle membrane
namespace: cellular_component
def:
  "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah]


id: GO:0031091
name: platelet alpha granule
namespace: cellular_component
def:
  "A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG)." [PMID:8467233]


id: GO:0031094
name: platelet dense tubular network
namespace: cellular_component
def:
  "A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin." [PMID:1322202]


id: GO:0031096
name: platelet dense tubular network lumen
namespace: cellular_component
def:
  "The volume enclosed by the membranes of the platelet dense tubular network." [GOC:mah, PMID:1322202]


id: GO:0031097
name: medial cortex
namespace: cellular_component
def:
  "A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation." [GOC:vw, PMID:15572668, PMID:19474789]


id: GO:0031098
name: stress-activated protein kinase signaling cascade
namespace: biological_process
def:
  "A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals." [GOC:mah]


id: GO:0031102
name: neuron projection regeneration
namespace: biological_process
def:
  "The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage." [GOC:dgh, GOC:dph, GOC:tb]


id: GO:0031105
name: septin complex
namespace: cellular_component
def:
  "A protein complex containing septins.  Typically, these complexes contain multiple septins and are oligomeric." [GOC:mah, PMID:15385632]


id: GO:0031108
name: holo-[acyl-carrier-protein] biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]." [GOC:mlg]


id: GO:0031109
name: microtubule polymerization or depolymerization
namespace: biological_process
def:
  "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah]


id: GO:0031110
name: regulation of microtubule polymerization or depolymerization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah]


id: GO:0031111
name: negative regulation of microtubule polymerization or depolymerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah]


id: GO:0031112
name: positive regulation of microtubule polymerization or depolymerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah]


id: GO:0031114
name: regulation of microtubule depolymerization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah]


id: GO:0031115
name: negative regulation of microtubule polymerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah]


id: GO:0031116
name: positive regulation of microtubule polymerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah]


id: GO:0031117
name: positive regulation of microtubule depolymerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah]


id: GO:0031121
name: equatorial microtubule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell." [GOC:mah, GOC:vw]


id: GO:0031122
name: cytoplasmic microtubule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah]


id: GO:0031127
name: alpha-(1,2)-fucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage." [GOC:mah]


id: GO:0031128
name: developmental induction
namespace: biological_process
def:
  "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535]


id: GO:0031129
name: inductive cell-cell signaling
namespace: biological_process
def:
  "Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate." [GOC:mah]


id: GO:0031130
name: creation of an inductive signal
namespace: biological_process
def:
  "The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter." [GOC:mah]


id: GO:0031131
name: reception of an inductive signal
namespace: biological_process
def:
  "The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change." [GOC:mah]


id: GO:0031132
name: serine 3-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH." [EC:1.1.1.276, RHEA:21599]


id: GO:0031133
name: regulation of axon diameter
namespace: biological_process
def:
  "Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031134
name: sister chromatid biorientation
namespace: biological_process
def:
  "The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles." [PMID:15309047]


id: GO:0031140
name: induction of conjugation upon nutrient starvation
namespace: biological_process
def:
  "The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients." [GOC:mah]


id: GO:0031141
name: induction of conjugation upon carbon starvation
namespace: biological_process
def:
  "The process in which a cell initiates conjugation with cellular fusion upon carbon starvation." [GOC:mah]


id: GO:0031142
name: induction of conjugation upon nitrogen starvation
namespace: biological_process
def:
  "The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation." [GOC:mah]


id: GO:0031143
name: pseudopodium
namespace: cellular_component
def:
  "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." [ISBN:0198506732]


id: GO:0031144
name: proteasome localization
namespace: biological_process
def:
  "Any process in which the proteasome is transported to, or maintained in, a specific location." [GOC:mah]


id: GO:0031145
name: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome." [PMID:15380083]


id: GO:0031146
name: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome." [PMID:15380083]


id: GO:0031147
name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells." [GOC:mah, PMID:10706822]


id: GO:0031148
name: DIF-1 biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells." [GOC:mah, PMID:10706822]


id: GO:0031149
name: sorocarp stalk cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:mah, GOC:mtg_sensu, ISBN:0521583640]


id: GO:0031150
name: sorocarp stalk development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:mtg_sensu, ISBN:0521583640]


id: GO:0031151
name: histone methyltransferase activity (H3-K79 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein." [GOC:mah, PMID:15371351]


id: GO:0031152
name: aggregation involved in sorocarp development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640]


id: GO:0031153
name: slug development involved in sorocarp development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640]


id: GO:0031154
name: culmination involved in sorocarp development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640]


id: GO:0031156
name: regulation of sorocarp development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:2530, GOC:mah, GOC:mtg_sensu]


id: GO:0031157
name: regulation of aggregate size involved in sorocarp development
namespace: biological_process
def:
  "Any process that modulates the size of the aggregate formed during sorocarp formation." [dictyBase_REF:5048, GOC:mah, GOC:mtg_sensu, GOC:pg]


id: GO:0031158
name: negative regulation of aggregate size involved in sorocarp development
namespace: biological_process
def:
  "Any process that decreases the size of the aggregate formed during sorocarp formation." [dictyBase_REF:5048, GOC:mah, GOC:mtg_sensu, GOC:pg]


id: GO:0031159
name: positive regulation of aggregate size involved in sorocarp development
namespace: biological_process
def:
  "Any process that increases the size of the aggregate formed during sorocarp formation." [dictyBase_REF:5048, GOC:mah, GOC:pg]


id: GO:0031161
name: phosphatidylinositol catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [GOC:mah]


id: GO:0031163
name: metallo-sulfur cluster assembly
namespace: biological_process
def:
  "The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster." [GOC:jl, GOC:mah, GOC:pde, GOC:vw]


id: GO:0031165
name: integral component of contractile vacuolar membrane
namespace: cellular_component
def:
  "The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer." [GOC:dos, GOC:pg]


id: GO:0031166
name: integral component of vacuolar membrane
namespace: cellular_component
def:
  "The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:dos, GOC:mah]


id: GO:0031167
name: rRNA methylation
namespace: biological_process
def:
  "The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule." [GOC:mah]


id: GO:0031168
name: ferrichrome metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:mah, ISBN:0198506732]


id: GO:0031169
name: ferrichrome biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:mah, ISBN:0198506732]


id: GO:0031170
name: ferricrocin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3." [GOC:mah, PMID:12828635]


id: GO:0031171
name: ferricrocin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3." [GOC:mah, PMID:12828635]


id: GO:0031172
name: ornithine N5-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O." [MetaCyc:RXN-11128, PMID:12828635]


id: GO:0031173
name: otolith mineralization completed early in development
namespace: biological_process
def:
  "The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear." [GOC:dsf, PMID:15581873]


id: GO:0031174
name: lifelong otolith mineralization
namespace: biological_process
def:
  "The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added." [GOC:dsf, PMID:15581873]


id: GO:0031175
name: neuron projection development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah]


id: GO:0031177
name: phosphopantetheine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate)." [CHEBI:16858, GOC:mah, GOC:vw]


id: GO:0031179
name: peptide modification
namespace: biological_process
def:
  "The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide." [GOC:mah]


id: GO:0031201
name: SNARE complex
namespace: cellular_component
def:
  "A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25." [GOC:bhm, GOC:pr, PMID:10872468, PMID:19450911]


id: GO:0031203
name: posttranslational protein targeting to membrane, docking
namespace: biological_process
def:
  "The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex." [PMID:12518217, PMID:8707814]


id: GO:0031204
name: posttranslational protein targeting to membrane, translocation
namespace: biological_process
def:
  "The process in which a protein translocates through the ER membrane posttranslationally." [PMID:12518317, PMID:8707814]


id: GO:0031205
name: endoplasmic reticulum Sec complex
namespace: cellular_component
def:
  "An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex." [GOC:mtg_sensu, PMID:12158317, PMID:14617809]


id: GO:0031207
name: Sec62/Sec63 complex
namespace: cellular_component
def:
  "A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p." [PMID:12518317, PMID:14617809]


id: GO:0031208
name: POZ domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors." [PMID:7958847]


id: GO:0031209
name: SCAR complex
namespace: cellular_component
def:
  "A heterotetrameric complex that includes orthologues of human PIR121, Nap125 and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction." [GOC:pg, PMID:12181570]


id: GO:0031210
name: phosphatidylcholine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:mah, ISBN:0198506732]


id: GO:0031211
name: endoplasmic reticulum palmitoyltransferase complex
namespace: cellular_component
def:
  "A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue." [GOC:jh]


id: GO:0031213
name: RSF complex
namespace: cellular_component
def:
  "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters)." [GOC:krc, PMID:12972596, PMID:15284901, PMID:16568949, PMID:21810179]


id: GO:0031214
name: biomineral tissue development
namespace: biological_process
def:
  "Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation." [PMID:15132736]


id: GO:0031215
name: shell calcification
namespace: biological_process
def:
  "The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell." [GOC:mah, PMID:15132736]


id: GO:0031216
name: neopullulanase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose)." [EC:3.2.1.135, GOC:mlg]


id: GO:0031217
name: glucan 1,4-beta-glucosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units." [EC:3.2.1.74, GOC:mlg]


id: GO:0031218
name: arabinogalactan endo-1,4-beta-galactosidase activity
namespace: molecular_function
def:
  "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans." [EC:3.2.1.89, GOC:mlg]


id: GO:0031219
name: levanase activity
namespace: molecular_function
def:
  "Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units." [EC:3.2.1.65, GOC:mlg]


id: GO:0031221
name: arabinan metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues." [GOC:mlg, ISBN:0198506732]


id: GO:0031222
name: arabinan catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues." [GOC:mlg, ISBN:0198506732]


id: GO:0031224
name: intrinsic component of membrane
namespace: cellular_component
def:
  "The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane." [GOC:mah]


id: GO:0031225
name: anchored component of membrane
namespace: cellular_component
def:
  "The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:mah]


id: GO:0031226
name: intrinsic component of plasma membrane
namespace: cellular_component
def:
  "The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031227
name: intrinsic component of endoplasmic reticulum membrane
namespace: cellular_component
def:
  "The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031228
name: intrinsic component of Golgi membrane
namespace: cellular_component
def:
  "The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031229
name: intrinsic component of nuclear inner membrane
namespace: cellular_component
def:
  "The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031230
name: intrinsic component of cell outer membrane
namespace: cellular_component
def:
  "The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031231
name: intrinsic component of peroxisomal membrane
namespace: cellular_component
def:
  "The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031232
name: extrinsic component of external side of plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031233
name: intrinsic component of external side of plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah]


id: GO:0031234
name: extrinsic component of cytoplasmic side of plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region." [GOC:mah]


id: GO:0031235
name: intrinsic component of the cytoplasmic side of the plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only." [GOC:dos, GOC:mah]


id: GO:0031236
name: extrinsic component of periplasmic side of plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031237
name: intrinsic component of periplasmic side of plasma membrane
namespace: cellular_component
def:
  "The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:mah, GOC:mtg_sensu]


id: GO:0031240
name: external side of cell outer membrane
namespace: cellular_component
def:
  "The side of the outer membrane that is opposite to the side that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu]


id: GO:0031241
name: periplasmic side of cell outer membrane
namespace: cellular_component
def:
  "The side (leaflet) of the outer membrane that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu]


id: GO:0031242
name: extrinsic component of external side of cell outer membrane
namespace: cellular_component
def:
  "The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031243
name: intrinsic component of external side of cell outer membrane
namespace: cellular_component
def:
  "The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031244
name: extrinsic component of cell outer membrane
namespace: cellular_component
def:
  "The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031245
name: extrinsic component of periplasmic side of cell outer membrane
namespace: cellular_component
def:
  "The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031246
name: intrinsic component of periplasmic side of cell outer membrane
namespace: cellular_component
def:
  "The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah, GOC:mtg_sensu]


id: GO:0031247
name: actin rod assembly
namespace: biological_process
def:
  "The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules." [GOC:pg, PMID:14706699]


id: GO:0031250
name: anaerobic ribonucleoside-triphosphate reductase complex
namespace: cellular_component
def:
  "An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit." [GOC:mlg]


id: GO:0031251
name: PAN complex
namespace: cellular_component
def:
  "A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces." [PMID:9774670]


id: GO:0031261
name: DNA replication preinitiation complex
namespace: cellular_component
def:
  "A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present." [GOC:bf, GOC:hjd, GOC:jl, GOC:pr, GOC:rb, GOC:vw, PMID:12694535, PMID:15194812]


id: GO:0031262
name: Ndc80 complex
namespace: cellular_component
def:
  "A protein complex conserved among eukaryotes that forms part of the kinetochore and plays an essential role in forming stable kinetochore-microtubule attachments. The complex contains proteins known in several species, including budding and fission yeasts, as Ndc80p, Nuf2p, Spc24p, and Spc25p. In vertebrates it is part of the outer plate of the kinetochore." [PMID:15509863, PMID:15661517]


id: GO:0031264
name: death-inducing signaling complex
namespace: cellular_component
def:
  "A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10." [GOC:mtg_apoptosis, PMID:12628743, PMID:12655293, PMID:8521815]


id: GO:0031265
name: CD95 death-inducing signaling complex
namespace: cellular_component
def:
  "A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293]


id: GO:0031266
name: TRAIL death-inducing signaling complex
namespace: cellular_component
def:
  "A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293]


id: GO:0031268
name: pseudopodium organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement." [GOC:pg]


id: GO:0031269
name: pseudopodium assembly
namespace: biological_process
def:
  "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane." [GOC:dph, GOC:mah, GOC:pg, GOC:tb]


id: GO:0031271
name: lateral pseudopodium assembly
namespace: biological_process
def:
  "The extension of a pseudopodium from the lateral area of a cell." [GOC:dph, GOC:mah, GOC:pg, GOC:tb]


id: GO:0031273
name: negative regulation of pseudopodium assembly
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg]


id: GO:0031274
name: positive regulation of pseudopodium assembly
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg]


id: GO:0031275
name: regulation of lateral pseudopodium assembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb]


id: GO:0031276
name: negative regulation of lateral pseudopodium assembly
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb]


id: GO:0031277
name: positive regulation of lateral pseudopodium assembly
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb]


id: GO:0031278
name: alpha-1,2-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage." [PMID:7522655]


id: GO:0031283
name: negative regulation of guanylate cyclase activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity." [GOC:mah]


id: GO:0031284
name: positive regulation of guanylate cyclase activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity." [GOC:mah]


id: GO:0031285
name: regulation of sorocarp stalk cell differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:kp, GOC:mtg_sensu]


id: GO:0031286
name: negative regulation of sorocarp stalk cell differentiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:kp, GOC:mtg_sensu]


id: GO:0031287
name: positive regulation of sorocarp stalk cell differentiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:kp, GOC:mtg_sensu]


id: GO:0031288
name: sorocarp morphogenesis
namespace: biological_process
def:
  "The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum." [dictyBase_REF:5048, GOC:kp, GOC:mtg_sensu]


id: GO:0031290
name: retinal ganglion cell axon guidance
namespace: biological_process
def:
  "The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:ejs]


id: GO:0031291
name: Ran protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state." [GOC:mah]


id: GO:0031292
name: gene conversion at mating-type locus, DNA double-strand break processing
namespace: biological_process
def:
  "The 5' to 3' exonucleolytic resection of the DNA at the site of the break at the mating-type locus to form a 3' single-strand DNA overhang." [GOC:mah]


id: GO:0031293
name: membrane protein intracellular domain proteolysis
namespace: biological_process
def:
  "The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain." [PMID:12808018]


id: GO:0031294
name: lymphocyte costimulation
namespace: biological_process
def:
  "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation." [ISBN:0781735149]


id: GO:0031295
name: T cell costimulation
namespace: biological_process
def:
  "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation." [ISBN:0781735149]


id: GO:0031296
name: B cell costimulation
namespace: biological_process
def:
  "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation." [ISBN:0781735149]


id: GO:0031297
name: replication fork processing
namespace: biological_process
def:
  "The process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted." [PMID:11459955, PMID:15367656, PMID:17660542]


id: GO:0031298
name: replication fork protection complex
namespace: cellular_component
def:
  "A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling." [PMID:15367656]


id: GO:0031299
name: taurine-pyruvate aminotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde." [EC:2.6.1.77, RHEA:10423]


id: GO:0031300
name: intrinsic component of organelle membrane
namespace: cellular_component
def:
  "The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031301
name: integral component of organelle membrane
namespace: cellular_component
def:
  "The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031302
name: intrinsic component of endosome membrane
namespace: cellular_component
def:
  "The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031303
name: integral component of endosome membrane
namespace: cellular_component
def:
  "The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031304
name: intrinsic component of mitochondrial inner membrane
namespace: cellular_component
def:
  "The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031305
name: integral component of mitochondrial inner membrane
namespace: cellular_component
def:
  "The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031306
name: intrinsic component of mitochondrial outer membrane
namespace: cellular_component
def:
  "The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031307
name: integral component of mitochondrial outer membrane
namespace: cellular_component
def:
  "The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031308
name: intrinsic component of nuclear outer membrane
namespace: cellular_component
def:
  "The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031309
name: integral component of nuclear outer membrane
namespace: cellular_component
def:
  "The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031310
name: intrinsic component of vacuolar membrane
namespace: cellular_component
def:
  "The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031311
name: intrinsic component of contractile vacuolar membrane
namespace: cellular_component
def:
  "The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031312
name: extrinsic component of organelle membrane
namespace: cellular_component
def:
  "The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031313
name: extrinsic component of endosome membrane
namespace: cellular_component
def:
  "The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031314
name: extrinsic component of mitochondrial inner membrane
namespace: cellular_component
def:
  "The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031315
name: extrinsic component of mitochondrial outer membrane
namespace: cellular_component
def:
  "The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031316
name: extrinsic component of nuclear outer membrane
namespace: cellular_component
def:
  "The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0031317
name: tripartite ATP-independent periplasmic transporter complex
namespace: cellular_component
def:
  "A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients." [GOC:mlg]


id: GO:0031318
name: detection of folic acid
namespace: biological_process
def:
  "The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal." [GOC:pg]


id: GO:0031319
name: detection of cAMP
namespace: biological_process
def:
  "The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP." [GOC:pg]


id: GO:0031321
name: ascospore-type prospore assembly
namespace: biological_process
def:
  "During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane." [GOC:mah, PMID:14702385]


id: GO:0031322
name: ascospore-type prospore-specific spindle pole body remodeling
namespace: biological_process
def:
  "A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)." [GOC:mah, PMID:14702385]


id: GO:0031323
name: regulation of cellular metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]


id: GO:0031324
name: negative regulation of cellular metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]


id: GO:0031325
name: positive regulation of cellular metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]


id: GO:0031326
name: regulation of cellular biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]


id: GO:0031327
name: negative regulation of cellular biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]


id: GO:0031328
name: positive regulation of cellular biosynthetic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]


id: GO:0031329
name: regulation of cellular catabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]


id: GO:0031330
name: negative regulation of cellular catabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]


id: GO:0031331
name: positive regulation of cellular catabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]


id: GO:0031332
name: RNAi effector complex
namespace: cellular_component
def:
  "Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins." [GOC:mah, PMID:14704433]


id: GO:0031333
name: negative regulation of protein complex assembly
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah]


id: GO:0031334
name: positive regulation of protein complex assembly
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah]


id: GO:0031335
name: regulation of sulfur amino acid metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah]


id: GO:0031336
name: negative regulation of sulfur amino acid metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah]


id: GO:0031337
name: positive regulation of sulfur amino acid metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah]


id: GO:0031339
name: negative regulation of vesicle fusion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah]


id: GO:0031340
name: positive regulation of vesicle fusion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah]


id: GO:0031341
name: regulation of cell killing
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism." [GOC:mah]


id: GO:0031342
name: negative regulation of cell killing
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing." [GOC:mah]


id: GO:0031344
name: regulation of cell projection organization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]


id: GO:0031345
name: negative regulation of cell projection organization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]


id: GO:0031346
name: positive regulation of cell projection organization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]


id: GO:0031348
name: negative regulation of defense response
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah]


id: GO:0031349
name: positive regulation of defense response
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah]


id: GO:0031350
name: intrinsic component of plastid membrane
namespace: cellular_component
def:
  "The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031351
name: integral component of plastid membrane
namespace: cellular_component
def:
  "The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031352
name: intrinsic component of plastid inner membrane
namespace: cellular_component
def:
  "The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031353
name: integral component of plastid inner membrane
namespace: cellular_component
def:
  "The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031354
name: intrinsic component of plastid outer membrane
namespace: cellular_component
def:
  "The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031355
name: integral component of plastid outer membrane
namespace: cellular_component
def:
  "The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031356
name: intrinsic component of chloroplast inner membrane
namespace: cellular_component
def:
  "The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031357
name: integral component of chloroplast inner membrane
namespace: cellular_component
def:
  "The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031358
name: intrinsic component of chloroplast outer membrane
namespace: cellular_component
def:
  "The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031359
name: integral component of chloroplast outer membrane
namespace: cellular_component
def:
  "The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031360
name: intrinsic component of thylakoid membrane
namespace: cellular_component
def:
  "The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah]


id: GO:0031361
name: integral component of thylakoid membrane
namespace: cellular_component
def:
  "The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0031362
name: anchored component of external side of plasma membrane
namespace: cellular_component
def:
  "The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:mah]


id: GO:0031364
name: N-terminal protein amino acid deamination, from side chain
namespace: biological_process
def:
  "The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein." [GOC:mah]


id: GO:0031366
name: N-terminal peptidyl-asparagine deamination
namespace: biological_process
def:
  "The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein." [GOC:bf, GOC:mah]


id: GO:0031367
name: N-terminal peptidyl-glutamine deamination
namespace: biological_process
def:
  "The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein." [GOC:mah]


id: GO:0031368
name: obsolete Pro-X metallocarboxypeptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid." [EC:3.4.17.16, GOC:mah]


id: GO:0031369
name: translation initiation factor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah]


id: GO:0031370
name: eukaryotic initiation factor 4G binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah]


id: GO:0031372
name: UBC13-MMS2 complex
namespace: cellular_component
def:
  "A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p." [GOC:mah, PMID:15772086]


id: GO:0031375
name: obsolete type II fatty acid synthase complex
namespace: cellular_component
def:
  "OBSOLETE A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385]


id: GO:0031376
name: obsolete cytosolic type II fatty acid synthase complex
namespace: cellular_component
def:
  "OBSOLETE A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385]


id: GO:0031377
name: obsolete mitochondrial type II fatty acid synthase complex
namespace: cellular_component
def:
  "OBSOLETE A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385]


id: GO:0031378
name: obsolete plastid type II fatty acid synthase complex
namespace: cellular_component
def:
  "OBSOLETE A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385]


id: GO:0031380
name: nuclear RNA-directed RNA polymerase complex
namespace: cellular_component
def:
  "A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain." [GOC:vw, PMID:15607976]


id: GO:0031381
name: viral RNA-directed RNA polymerase complex
namespace: cellular_component
def:
  "A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus." [GOC:mah, PMID:15574411, PMID:15613301]


id: GO:0031382
name: mating projection assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi." [GOC:mah, PMID:14734532]


id: GO:0031383
name: regulation of mating projection assembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi." [PMID:14734532]


id: GO:0031384
name: regulation of initiation of mating projection growth
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi." [PMID:14734532]


id: GO:0031385
name: regulation of termination of mating projection growth
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi." [PMID:14734532]


id: GO:0031386
name: protein tag
namespace: molecular_function
def:
  "Acting as an indicator or marker to facilitate recognition by other molecules in the cell. Recognition of the tag, which can be covalently attached to the target molecule, may result in modification, sequestration, transport or degradation of the molecule in question." [GOC:go_curators]


id: GO:0031387
name: MPF complex
namespace: cellular_component
def:
  "A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC)." [PMID:12045216]


id: GO:0031389
name: Rad17 RFC-like complex
namespace: cellular_component
def:
  "A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842]


id: GO:0031390
name: Ctf18 RFC-like complex
namespace: cellular_component
def:
  "A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p." [PMID:14614842]


id: GO:0031391
name: Elg1 RFC-like complex
namespace: cellular_component
def:
  "A pentameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842]


id: GO:0031392
name: regulation of prostaglandin biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah]


id: GO:0031393
name: negative regulation of prostaglandin biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah]


id: GO:0031394
name: positive regulation of prostaglandin biosynthetic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah]


id: GO:0031395
name: bursicon neuropeptide hormone complex
namespace: cellular_component
def:
  "A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits." [GOC:rc]


id: GO:0031396
name: regulation of protein ubiquitination
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah]


id: GO:0031397
name: negative regulation of protein ubiquitination
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah]


id: GO:0031398
name: positive regulation of protein ubiquitination
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah]


id: GO:0031399
name: regulation of protein modification process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb]


id: GO:0031400
name: negative regulation of protein modification process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb]


id: GO:0031401
name: positive regulation of protein modification process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb]


id: GO:0031405
name: lipoic acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid." [GOC:mah, ISBN:0198506732]


id: GO:0031406
name: carboxylic acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:mah, ISBN:0198506732]


id: GO:0031407
name: oxylipin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids." [GOC:mah, PMID:11960741]


id: GO:0031408
name: oxylipin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids." [GOC:mah, PMID:11960741]


id: GO:0031409
name: pigment binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin." [GOC:mah]


id: GO:0031411
name: gas vesicle
namespace: cellular_component
def:
  "An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations." [PMID:22147705, PMID:8177173]


id: GO:0031412
name: gas vesicle organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps." [GOC:mah]


id: GO:0031413
name: regulation of buoyancy
namespace: biological_process
def:
  "Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases." [GOC:mah, PATO:0001420]


id: GO:0031414
name: N-terminal protein acetyltransferase complex
namespace: cellular_component
def:
  "A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule." [GOC:mah]


id: GO:0031415
name: NatA complex
namespace: cellular_component
def:
  "A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins." [PMID:12890471]


id: GO:0031416
name: NatB complex
namespace: cellular_component
def:
  "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p." [PMID:12890471]


id: GO:0031417
name: NatC complex
namespace: cellular_component
def:
  "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p." [PMID:12890471]


id: GO:0031418
name: L-ascorbic acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species." [CHEBI:38290, GOC:mah]


id: GO:0031419
name: cobalamin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:mah]


id: GO:0031420
name: alkali metal ion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen." [GOC:mah]


id: GO:0031421
name: invertasome
namespace: cellular_component
def:
  "A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts." [PMID:11114897, PMID:9732277]


id: GO:0031422
name: RecQ helicase-Topo III complex
namespace: cellular_component
def:
  "A complex containing a RecQ family helicase and a topoisomerase III homologue; may also include one or more additional proteins; conserved from E. coli to human." [PMID:15889139]


id: GO:0031423
name: hexon binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a hexon, the major protein component of the icosahedral capsid of an adenovirus." [GOC:mah, PMID:12915569]


id: GO:0031424
name: keratinization
namespace: biological_process
def:
  "The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns." [GOC:dph, GOC:ebc, GOC:sdb_2009, GOC:tb]


id: GO:0031425
name: chloroplast RNA processing
namespace: biological_process
def:
  "The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules." [GOC:mah]


id: GO:0031426
name: polycistronic mRNA processing
namespace: biological_process
def:
  "The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules." [GOC:mah]


id: GO:0031427
name: response to methotrexate
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase." [CHEBI:44185, GOC:ef, GOC:mah, ISBN:0198506732]


id: GO:0031428
name: box C/D snoRNP complex
namespace: cellular_component
def:
  "A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs." [ISBN:0879695897, PMID:17284456]


id: GO:0031429
name: box H/ACA snoRNP complex
namespace: cellular_component
def:
  "A box H/ACA RNP complex that is located in the nucleolus." [GOC:vw, ISBN:0879695897, PMID:17284456, PMID:20227365]


id: GO:0031430
name: M band
namespace: cellular_component
def:
  "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." [GOC:mtg_muscle, ISBN:0198506732, ISBN:0815316194]


id: GO:0031431
name: Dbf4-dependent protein kinase complex
namespace: cellular_component
def:
  "A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins." [PMID:12045100]


id: GO:0031432
name: titin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively." [GOC:mah, PMID:10481174]


id: GO:0031433
name: telethonin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase." [GOC:mah, PMID:10481174]


id: GO:0031434
name: mitogen-activated protein kinase kinase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase." [GOC:mah]


id: GO:0031435
name: mitogen-activated protein kinase kinase kinase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase." [GOC:bf]


id: GO:0031436
name: BRCA1-BARD1 complex
namespace: cellular_component
def:
  "A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage." [PMID:12787778]


id: GO:0031437
name: regulation of mRNA cleavage
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner." [GOC:mah]


id: GO:0031438
name: negative regulation of mRNA cleavage
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage." [GOC:mah]


id: GO:0031440
name: regulation of mRNA 3'-end processing
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule." [GOC:mah]


id: GO:0031441
name: negative regulation of mRNA 3'-end processing
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah]


id: GO:0031442
name: positive regulation of mRNA 3'-end processing
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah]


id: GO:0031443
name: fast-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability." [GOC:ef, GOC:mah, GOC:mtg_muscle]


id: GO:0031444
name: slow-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue." [GOC:ef, GOC:mah, GOC:mtg_muscle]


id: GO:0031445
name: regulation of heterochromatin assembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, extent or location of heterochromatin formation." [GOC:mah]


id: GO:0031446
name: regulation of fast-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031447
name: negative regulation of fast-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031448
name: positive regulation of fast-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031449
name: regulation of slow-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031450
name: negative regulation of slow-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031451
name: positive regulation of slow-twitch skeletal muscle fiber contraction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb]


id: GO:0031452
name: negative regulation of heterochromatin assembly
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation." [GOC:mah]


id: GO:0031453
name: positive regulation of heterochromatin assembly
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of heterochromatin formation." [GOC:mah]


id: GO:0031456
name: glycine betaine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine." [GOC:mah]


id: GO:0031457
name: glycine betaine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine." [GOC:mah]


id: GO:0031458
name: betaine-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in)." [GOC:mlg]


id: GO:0031459
name: glycine betaine-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in)." [GOC:mlg]


id: GO:0031460
name: glycine betaine transport
namespace: biological_process
def:
  "The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0031461
name: cullin-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity." [PMID:15571813, PMID:15688063]


id: GO:0031462
name: Cul2-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063]


id: GO:0031463
name: Cul3-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein." [PMID:15571813, PMID:15688063]


id: GO:0031464
name: Cul4A-RING E3 ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein." [PMID:15571813, PMID:15688063]


id: GO:0031465
name: Cul4B-RING E3 ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits." [PMID:15571813, PMID:15688063]


id: GO:0031466
name: Cul5-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063]


id: GO:0031467
name: Cul7-RING ubiquitin ligase complex
namespace: cellular_component
def:
  "A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein." [PMID:15571813, PMID:15688063]


id: GO:0031468
name: nuclear envelope reassembly
namespace: biological_process
def:
  "The reformation of the nuclear envelope following its breakdown in the context of a normal process." [GOC:mah]


id: GO:0031469
name: polyhedral organelle
namespace: cellular_component
def:
  "An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081]


id: GO:0031470
name: carboxysome
namespace: cellular_component
def:
  "An organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide including mechanisms for the concentration of carbonate to increase the efficiency of fixation under low-carbon dioxide conditions." [GOC:js, PMID:8157606, PMID:8491708]


id: GO:0031471
name: ethanolamine degradation polyhedral organelle
namespace: cellular_component
def:
  "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase." [GOC:js, PMID:11844753]


id: GO:0031472
name: propanediol degradation polyhedral organelle
namespace: cellular_component
def:
  "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081]


id: GO:0031473
name: myosin III binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a class III myosin; myosin III is monomeric and has an N terminal kinase domain." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031474
name: myosin IV complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031475
name: myosin V complex
namespace: cellular_component
def:
  "A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031476
name: myosin VI complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031477
name: myosin VII complex
namespace: cellular_component
def:
  "A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031478
name: myosin VIII complex
namespace: cellular_component
def:
  "A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031479
name: myosin IX complex
namespace: cellular_component
def:
  "A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031480
name: myosin X complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class X myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031481
name: myosin XI complex
namespace: cellular_component
def:
  "A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031482
name: myosin XII complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031483
name: myosin XIII complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class XIII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031484
name: myosin XIV complex
namespace: cellular_component
def:
  "A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031485
name: myosin XV complex
namespace: cellular_component
def:
  "A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031486
name: myosin XVI complex
namespace: cellular_component
def:
  "A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:11294886]


id: GO:0031487
name: myosin XVII complex
namespace: cellular_component
def:
  "A myosin complex containing one or more class XVII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031488
name: myosin XVIII complex
namespace: cellular_component
def:
  "A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain." [PMID:11294886]


id: GO:0031489
name: myosin V binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html]


id: GO:0031491
name: nucleosome binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures." [GOC:mah]


id: GO:0031493
name: nucleosomal histone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a histone that is assembled into a nucleosome." [GOC:mah]


id: GO:0031494
name: regulation of mating type switching
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [GOC:mah]


id: GO:0031495
name: negative regulation of mating type switching
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching." [GOC:mah]


id: GO:0031496
name: positive regulation of mating type switching
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of mating type switching." [GOC:mah]


id: GO:0031497
name: chromatin assembly
namespace: biological_process
def:
  "The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus." [http://www.infobiogen.fr/services/chromcancer/IntroItems/ChromatinEducEng.html, PMID:20404130]


id: GO:0031498
name: chromatin disassembly
namespace: biological_process
def:
  "The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA." [http://www.infobiogen.fr/services/chromcancer/IntroItems/ChromatinEducEng.html, PMID:20404130]


id: GO:0031499
name: TRAMP complex
namespace: cellular_component
def:
  "A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control." [PMID:15173578, PMID:15828860, PMID:15935758, PMID:15935759, PMID:16373491, PMID:16374505, PMID:16431988, PMID:16973437, PMID:17410208, PMID:17652137]


id: GO:0031500
name: Tea1 cell-end complex
namespace: cellular_component
def:
  "A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity." [PMID:15936270]


id: GO:0031502
name: dolichyl-phosphate-mannose-protein mannosyltransferase complex
namespace: cellular_component
def:
  "A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies." [GOC:mah, GOC:pr, PMID:15948957]


id: GO:0031503
name: protein complex localization
namespace: biological_process
def:
  "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah]


id: GO:0031504
name: peptidoglycan-based cell wall organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall." [GOC:dph, GOC:jl, GOC:mah, GOC:mtg_sensu]


id: GO:0031505
name: fungal-type cell wall organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GOC:dph, GOC:jl, GOC:mah, GOC:mtg_sensu]


id: GO:0031506
name: cell wall glycoprotein biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues." [GOC:mah]


id: GO:0031507
name: heterochromatin assembly
namespace: biological_process
def:
  "The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent." [GOC:mah]


id: GO:0031508
name: pericentric heterochromatin assembly
namespace: biological_process
def:
  "The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3." [GOC:mah, PMID:20206496, PMID:22729156]


id: GO:0031511
name: Mis6-Sim4 complex
namespace: cellular_component
def:
  "A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human." [GOC:vw, PMID:12719471, PMID:15897182]


id: GO:0031512
name: motile primary cilium
namespace: cellular_component
def:
  "A primary cilium which may contain a variable array of axonemal microtubules and also contains molecular motors. Motile primary cilia display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization." [GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998]


id: GO:0031513
name: nonmotile primary cilium
namespace: cellular_component
def:
  "A primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules." [GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998]


id: GO:0031514
name: motile cilium
namespace: cellular_component
def:
  "A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles." [GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998]


id: GO:0031515
name: tRNA (m1A) methyltransferase complex
namespace: cellular_component
def:
  "A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer." [PMID:10779558, PMID:14739239]


id: GO:0031516
name: far-red light photoreceptor activity
namespace: molecular_function
def:
  "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation." [GOC:nln]


id: GO:0031517
name: red light photoreceptor activity
namespace: molecular_function
def:
  "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation." [GOC:nln]


id: GO:0031518
name: CBF3 complex
namespace: cellular_component
def:
  "A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p." [PMID:13679521, PMID:9407032]


id: GO:0031519
name: PcG protein complex
namespace: cellular_component
def:
  "A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure." [PMID:9372908]


id: GO:0031521
name: spitzenkorper
namespace: cellular_component
def:
  "Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments." [PMID:15701784, PMID:15976451]


id: GO:0031522
name: cell envelope Sec protein transport complex
namespace: cellular_component
def:
  "A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC." [GOC:mtg_sensu, PMID:15223057]


id: GO:0031523
name: Myb complex
namespace: cellular_component
def:
  "A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression." [PMID:12490953, PMID:15545624]


id: GO:0031524
name: menthol metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol." [GOC:mah]


id: GO:0031525
name: menthol biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol." [GOC:mah]


id: GO:0031529
name: ruffle organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell." [GOC:mah, PMID:10036235]


id: GO:0031530
name: gonadotropin-releasing hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary." [GOC:pr, PMID:15196882]


id: GO:0031531
name: thyrotropin-releasing hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary." [PMID:8592728]


id: GO:0031532
name: actin cytoskeleton reorganization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ecd, GOC:mah]


id: GO:0031533
name: mRNA cap methyltransferase complex
namespace: cellular_component
def:
  "A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping." [GOC:vw, PMID:10347220]


id: GO:0031534
name: minus-end directed microtubule sliding
namespace: biological_process
def:
  "The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules." [GOC:mah, GOC:vw]


id: GO:0031535
name: plus-end directed microtubule sliding
namespace: biological_process
def:
  "The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules." [GOC:mah, GOC:vw]


id: GO:0031536
name: positive regulation of exit from mitosis
namespace: biological_process
def:
  "Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:mah]


id: GO:0031537
name: regulation of anthocyanin metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah]


id: GO:0031538
name: negative regulation of anthocyanin metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah]


id: GO:0031539
name: positive regulation of anthocyanin metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah]


id: GO:0031540
name: regulation of anthocyanin biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah]


id: GO:0031541
name: negative regulation of anthocyanin biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah]


id: GO:0031542
name: positive regulation of anthocyanin biosynthetic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah]


id: GO:0031543
name: peptidyl-proline dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2." [GOC:mah, GOC:vw, PMID:24550447, PMID:24550462]


id: GO:0031544
name: peptidyl-proline 3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2." [GOC:mah]


id: GO:0031545
name: peptidyl-proline 4-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2." [GOC:mah]


id: GO:0031546
name: brain-derived neurotrophic factor receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the brain-derived neurotrophic factor receptor." [GOC:mah]


id: GO:0031547
name: brain-derived neurotrophic factor receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands." [GOC:mah]


id: GO:0031548
name: regulation of brain-derived neurotrophic factor receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah]


id: GO:0031549
name: negative regulation of brain-derived neurotrophic factor receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah]


id: GO:0031550
name: positive regulation of brain-derived neurotrophic factor receptor signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah]


id: GO:0031551
name: regulation of brain-derived neurotrophic factor-activated receptor activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah]


id: GO:0031552
name: negative regulation of brain-derived neurotrophic factor-activated receptor activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah]


id: GO:0031553
name: positive regulation of brain-derived neurotrophic factor-activated receptor activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah]


id: GO:0031554
name: regulation of DNA-templated transcription, termination
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:mlg, GOC:txnOH]


id: GO:0031555
name: transcriptional attenuation
namespace: biological_process
def:
  "Regulation of transcription through variation in where transcription termination occurs." [GOC:dh, GOC:mlg, ISBN:0198542682]


id: GO:0031556
name: transcriptional attenuation by ribosome
namespace: biological_process
def:
  "A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch." [GOC:dh, GOC:mlg, ISBN:0198542682]


id: GO:0031557
name: obsolete induction of programmed cell death in response to chemical stimulus
namespace: biological_process
def:
  "OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0031558
name: obsolete induction of apoptosis in response to chemical stimulus
namespace: biological_process
def:
  "OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0031560
name: cellular bud neck polarisome
namespace: cellular_component
def:
  "Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis." [PMID:9632790]


id: GO:0031561
name: cellular bud tip polarisome
namespace: cellular_component
def:
  "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud." [PMID:9632790]


id: GO:0031562
name: hyphal tip polarisome
namespace: cellular_component
def:
  "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha." [PMID:15976451]


id: GO:0031563
name: mating projection tip polarisome
namespace: cellular_component
def:
  "Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone." [PMID:14734532]


id: GO:0031564
name: transcription antitermination
namespace: biological_process
def:
  "Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site." [ISBN:0198577788, PMID:12456320]


id: GO:0031565
name: obsolete cytokinesis checkpoint
namespace: biological_process
def:
  "OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition." [GOC:mtg_cell_cycle]


id: GO:0031566
name: actomyosin contractile ring maintenance
namespace: biological_process
def:
  "The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle." [GOC:dph, GOC:mah, GOC:tb, GOC:vw]


id: GO:0031567
name: mitotic cell size control checkpoint
namespace: biological_process
def:
  "The mitotic cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size." [GOC:mtg_cell_cycle]


id: GO:0031568
name: G1 cell size control checkpoint
namespace: biological_process
def:
  "A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G1 and S phase until a critical size is reached." [GOC:mtg_cell_cycle]


id: GO:0031569
name: G2 cell size control checkpoint
namespace: biological_process
def:
  "A cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G2 and M phase until a critical size is reached." [GOC:mtg_cell_cycle]


id: GO:0031570
name: DNA integrity checkpoint
namespace: biological_process
def:
  "A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes." [GOC:mtg_cell_cycle]


id: GO:0031571
name: mitotic G1 DNA damage checkpoint
namespace: biological_process
def:
  "A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S transition of the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle]


id: GO:0031572
name: G2 DNA damage checkpoint
namespace: biological_process
def:
  "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle]


id: GO:0031573
name: intra-S DNA damage checkpoint
namespace: biological_process
def:
  "A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression." [GOC:vw]


id: GO:0031578
name: mitotic spindle orientation checkpoint
namespace: biological_process
def:
  "A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected." [GOC:mtg_cell_cycle, PMID:14616062]


id: GO:0031579
name: membrane raft organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:dph, GOC:jl, GOC:mah]


id: GO:0031580
name: membrane raft distribution
namespace: biological_process
def:
  "The process that establishes the spatial arrangement of membrane rafts within a cellular membrane." [GOC:mah]


id: GO:0031581
name: hemidesmosome assembly
namespace: biological_process
def:
  "Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina." [GOC:dgh, PMID:15983403]


id: GO:0031582
name: replication fork arrest at rDNA repeats
namespace: biological_process
def:
  "A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer." [GOC:mah, GOC:vw]


id: GO:0031583
name: phospholipase D-activating G-protein coupled receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA)." [GOC:mah, GOC:signaling, PMID:11812783, PMID:15924269]


id: GO:0031585
name: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling]


id: GO:0031586
name: negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling]


id: GO:0031587
name: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling]


id: GO:0031588
name: nucleotide-activated protein kinase complex
namespace: cellular_component
def:
  "A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae)." [GOC:bhm, GOC:mah, GOC:vw]


id: GO:0031590
name: wybutosine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules." [GOC:mah, RNAmods:037]


id: GO:0031591
name: wybutosine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules." [GOC:hjd, GOC:mah, RNAmods:037]


id: GO:0031592
name: centrosomal corona
namespace: cellular_component
def:
  "An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin." [GOC:kp, GOC:mah]


id: GO:0031594
name: neuromuscular junction
namespace: cellular_component
def:
  "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln]


id: GO:0031599
name: obsolete ER proteasome regulatory particle
namespace: cellular_component
def:
  "OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031600
name: cytosolic proteasome regulatory particle
namespace: cellular_component
def:
  "A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex." [GOC:mah, GOC:mtg_sensu]


id: GO:0031602
name: obsolete ER proteasome core complex
namespace: cellular_component
def:
  "OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031604
name: nuclear proteasome core complex, alpha-subunit complex
namespace: cellular_component
def:
  "The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah]


id: GO:0031605
name: obsolete ER proteasome core complex, alpha-subunit complex
namespace: cellular_component
def:
  "OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031606
name: cytosolic proteasome core complex, alpha-subunit complex
namespace: cellular_component
def:
  "The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu]


id: GO:0031607
name: nuclear proteasome core complex, beta-subunit complex
namespace: cellular_component
def:
  "The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah]


id: GO:0031608
name: obsolete ER proteasome core complex, beta-subunit complex
namespace: cellular_component
def:
  "OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031609
name: cytosolic proteasome core complex, beta-subunit complex
namespace: cellular_component
def:
  "The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu]


id: GO:0031610
name: nuclear proteasome regulatory particle, base subcomplex
namespace: cellular_component
def:
  "The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell." [GOC:mah]


id: GO:0031611
name: obsolete ER proteasome regulatory particle, base subcomplex
namespace: cellular_component
def:
  "OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031612
name: cytosolic proteasome regulatory particle, base subcomplex
namespace: cellular_component
def:
  "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell." [GOC:mah, GOC:mtg_sensu]


id: GO:0031613
name: nuclear proteasome regulatory particle, lid subcomplex
namespace: cellular_component
def:
  "The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell." [GOC:mah]


id: GO:0031614
name: obsolete ER proteasome regulatory particle, lid subcomplex
namespace: cellular_component
def:
  "OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah]


id: GO:0031615
name: cytosolic proteasome regulatory particle, lid subcomplex
namespace: cellular_component
def:
  "The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:mah, GOC:mtg_sensu]


id: GO:0031617
name: NMS complex
namespace: cellular_component
def:
  "A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes." [PMID:16079914]


id: GO:0031618
name: nuclear pericentric heterochromatin
namespace: cellular_component
def:
  "Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3." [GOC:mah, PMID:20206496, PMID:22729156, PMID:9413993]


id: GO:0031619
name: homologous chromosome orientation involved in meiotic metaphase I plate congression
namespace: biological_process
def:
  "The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:15062096]


id: GO:0031621
name: negative regulation of fever generation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the rate or extent of fever generation." [GOC:add, GOC:dph, GOC:tb]


id: GO:0031622
name: positive regulation of fever generation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of fever generation." [GOC:add]


id: GO:0031623
name: receptor internalization
namespace: biological_process
def:
  "A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane." [GOC:bf, GOC:mah, GOC:signaling, PMID:15006537, PMID:19643732]


id: GO:0031624
name: ubiquitin conjugating enzyme binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins." [GOC:vp]


id: GO:0031625
name: ubiquitin protein ligase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins." [GOC:vp]


id: GO:0031626
name: beta-endorphin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin." [GOC:nln, PMID:6267560]


id: GO:0031627
name: telomeric loop formation
namespace: biological_process
def:
  "The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region." [GOC:vw, PMID:10338214]


id: GO:0031629
name: synaptic vesicle fusion to presynaptic active zone membrane
namespace: biological_process
def:
  "Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft." [ISBN:0071120009]


id: GO:0031630
name: regulation of synaptic vesicle fusion to presynaptic membrane
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah]


id: GO:0031631
name: negative regulation of synaptic vesicle fusion to presynaptic membrane
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah]


id: GO:0031632
name: positive regulation of synaptic vesicle fusion to presynaptic membrane
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah]


id: GO:0031634
name: replication fork barrier binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks." [GOC:mah]


id: GO:0031635
name: adenylate cyclase-inhibiting opioid receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


id: GO:0031637
name: regulation of neuronal synaptic plasticity in response to neurotrophin
namespace: biological_process
def:
  "The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah, PMID:8703078]


id: GO:0031639
name: plasminogen activation
namespace: biological_process
def:
  "The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide." [PMID:9548733]


id: GO:0031640
name: killing of cells of other organism
namespace: biological_process
def:
  "Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions." [GOC:add]


id: GO:0031641
name: regulation of myelination
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah]


id: GO:0031642
name: negative regulation of myelination
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah]


id: GO:0031643
name: positive regulation of myelination
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah]


id: GO:0031644
name: regulation of neurological system process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031645
name: negative regulation of neurological system process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031646
name: positive regulation of neurological system process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031647
name: regulation of protein stability
namespace: biological_process
def:
  "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031648
name: protein destabilization
namespace: biological_process
def:
  "Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation." [GOC:mah]


id: GO:0031649
name: heat generation
namespace: biological_process
def:
  "Any homeostatic process in which an organism produces heat, thereby raising its internal temperature." [GOC:mah]


id: GO:0031651
name: negative regulation of heat generation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the rate or extent of heat generation." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031652
name: positive regulation of heat generation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of heat generation." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031653
name: heat dissipation
namespace: biological_process
def:
  "Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature." [GOC:mah]


id: GO:0031655
name: negative regulation of heat dissipation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the rate or extent of heat dissipation." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031656
name: positive regulation of heat dissipation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of heat dissipation." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031657
namespace: biological_process
name:
  regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

def:
  "Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:mtg_cell_cycle, GOC:pr]


id: GO:0031658
namespace: biological_process
name:
  negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb]


id: GO:0031659
namespace: biological_process
name:
  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

def:
  "Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb]


id: GO:0031660
namespace: biological_process
name:
  regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

def:
  "Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb]


id: GO:0031661
namespace: biological_process
name:
  negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb]


id: GO:0031662
namespace: biological_process
name:
  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

def:
  "Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity involved in the G2/M transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb]


id: GO:0031663
name: lipopolysaccharide-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system." [GOC:mah, GOC:signaling, PMID:15379975]


id: GO:0031664
name: regulation of lipopolysaccharide-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah]


id: GO:0031665
name: negative regulation of lipopolysaccharide-mediated signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah]


id: GO:0031666
name: positive regulation of lipopolysaccharide-mediated signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah]


id: GO:0031667
name: response to nutrient levels
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." [GOC:mah]


id: GO:0031668
name: cellular response to extracellular stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus." [GOC:mah]


id: GO:0031669
name: cellular response to nutrient levels
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." [GOC:mah]


id: GO:0031670
name: cellular response to nutrient
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus." [GOC:mah]


id: GO:0031671
name: primary cell septum biogenesis
namespace: biological_process
def:
  "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division." [GOC:jl]


id: GO:0031672
name: A band
namespace: cellular_component
def:
  "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." [ISBN:0321204131]


id: GO:0031673
name: H zone
namespace: cellular_component
def:
  "A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments." [GOC:mtg_muscle, ISBN:0321204131]


id: GO:0031674
name: I band
namespace: cellular_component
def:
  "A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end." [ISBN:0321204131]


id: GO:0031679
name: NADH dehydrogenase (plastoquinone) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol." [EC:1.6.99.6, GOC:mah]


id: GO:0031680
name: G-protein beta/gamma-subunit complex
namespace: cellular_component
def:
  "The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange." [GOC:mah]


id: GO:0031683
name: G-protein beta/gamma-subunit complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits." [GOC:nln, GOC:vw]


id: GO:0031684
name: heterotrimeric G-protein complex cycle
namespace: biological_process
def:
  "The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits." [GOC:nln]


id: GO:0031691
name: alpha-1A adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-1A adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031692
name: alpha-1B adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-1B adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031693
name: alpha-1D adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-1D adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031694
name: alpha-2A adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-2A adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031695
name: alpha-2B adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-2B adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031696
name: alpha-2C adrenergic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an alpha-2C adrenergic receptor." [GOC:mah, GOC:nln]


id: GO:0031704
name: apelin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an apelin receptor." [GOC:mah, GOC:nln, GOC:vp, PMID:12787050]


id: GO:0031709
name: gastrin-releasing peptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a gastrin-releasing peptide receptor." [GOC:mah, GOC:nln]


id: GO:0031714
name: C5a anaphylatoxin chemotactic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a C5a anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln]


id: GO:0031715
name: C5L2 anaphylatoxin chemotactic receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln]


id: GO:0031720
name: haptoglobin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex." [GOC:mah, ISBN:0198506732]


id: GO:0031740
name: type A cholecystokinin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type A cholecystokinin receptor." [GOC:mah, GOC:nln]


id: GO:0031741
name: type B gastrin/cholecystokinin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor." [GOC:mah, GOC:nln]


id: GO:0031745
name: cysteinyl leukotriene receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a cysteinyl leukotriene receptor." [GOC:mah, GOC:nln]


id: GO:0031746
name: type 1 cysteinyl leukotriene receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln]


id: GO:0031747
name: type 2 cysteinyl leukotriene receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln]


id: GO:0031753
name: endothelial differentiation G-protein coupled receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an endothelial differentiation G-protein coupled receptor." [GOC:mah, GOC:nln]


id: GO:0031754
name: Edg-1 sphingosine 1-phosphate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-1 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln]


id: GO:0031755
name: Edg-2 lysophosphatidic acid receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-2 lysophosphatidic acid receptor." [GOC:mah, GOC:nln]


id: GO:0031756
name: Edg-3 sphingosine 1-phosphate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-3 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln]


id: GO:0031757
name: Edg-4 lysophosphatidic acid receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor." [GOC:mah, GOC:nln]


id: GO:0031758
name: Edg-5 sphingosine 1-phosphate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-5 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln]


id: GO:0031759
name: Edg-6 sphingosine 1-phosphate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-6 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln]


id: GO:0031760
name: Edg-7 lysophosphatidic acid receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an Edg-7 lysophosphatidic acid receptor." [GOC:mah, GOC:nln]


id: GO:0031762
name: follicle-stimulating hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a follicle-stimulating hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031767
name: gastric inhibitory polypeptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a gastric inhibitory polypeptide receptor." [GOC:mah, GOC:nln]


id: GO:0031770
name: growth hormone-releasing hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a growth hormone-releasing hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031775
name: lutropin-choriogonadotropic hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031776
name: melanin-concentrating hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a melanin-concentrating hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031777
name: type 1 melanin-concentrating hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031778
name: type 2 melanin-concentrating hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031780
name: corticotropin hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a corticotropin hormone receptor." [GOC:dph, GOC:mah, GOC:nln]


id: GO:0031781
name: type 3 melanocortin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 3 melanocortin receptor." [GOC:mah, GOC:nln]


id: GO:0031782
name: type 4 melanocortin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 4 melanocortin receptor." [GOC:mah, GOC:nln]


id: GO:0031783
name: type 5 melanocortin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 5 melanocortin receptor." [GOC:mah, GOC:nln]


id: GO:0031789
name: G-protein coupled acetylcholine receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor." [GOC:bf, GOC:mah, GOC:nln]


id: GO:0031795
name: G-protein coupled GABA receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) GABA receptor." [GOC:mah, GOC:nln]


id: GO:0031796
name: type 1 metabotropic GABA receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 metabotropic GABA receptor." [GOC:mah, GOC:nln]


id: GO:0031797
name: type 2 metabotropic GABA receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 metabotropic GABA receptor." [GOC:mah, GOC:nln]


id: GO:0031798
name: type 1 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031799
name: type 2 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031800
name: type 3 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 3 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031801
name: type 4 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 4 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031802
name: type 5 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031803
name: type 6 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 6 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031804
name: type 7 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031805
name: type 8 metabotropic glutamate receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 8 metabotropic glutamate receptor." [GOC:mah, GOC:nln]


id: GO:0031806
name: G-protein coupled histamine receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) histamine receptor." [GOC:mah, GOC:nln, PMID:12679144]


id: GO:0031811
name: G-protein coupled nucleotide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) nucleotide receptor." [GOC:mah, GOC:nln]


id: GO:0031821
name: G-protein coupled serotonin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a metabotropic serotonin receptor." [GOC:mah, GOC:nln]


id: GO:0031839
name: type 1 neuromedin U receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 neuromedin U receptor." [GOC:mah, GOC:nln]


id: GO:0031840
name: type 2 neuromedin U receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 neuromedin U receptor." [GOC:mah, GOC:nln]


id: GO:0031842
name: type 1 neuropeptide Y receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 neuropeptide Y receptor." [GOC:mah, GOC:nln]


id: GO:0031843
name: type 2 neuropeptide Y receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 neuropeptide Y receptor." [GOC:mah, GOC:nln]


id: GO:0031844
name: type 4 neuropeptide Y receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 4 neuropeptide Y receptor." [GOC:mah, GOC:nln]


id: GO:0031845
name: type 5 neuropeptide Y receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 5 neuropeptide Y receptor." [GOC:mah, GOC:nln]


id: GO:0031848
name: protection from non-homologous end joining at telomere
namespace: biological_process
def:
  "A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse." [GOC:mah]


id: GO:0031852
name: mu-type opioid receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a mu-type opioid receptor." [GOC:mah, GOC:nln, GOC:sl]


id: GO:0031854
name: orexigenic neuropeptide QRFP receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an orexigenic neuropeptide QRFP receptor." [GOC:mah, GOC:nln]


id: GO:0031856
name: parathyroid hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a parathyroid hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031857
name: type 1 parathyroid hormone receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 parathyroid hormone receptor." [GOC:mah, GOC:nln]


id: GO:0031858
name: pituitary adenylate cyclase-activating polypeptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor." [GOC:mah, GOC:nln]


id: GO:0031859
name: platelet activating factor receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a platelet activating factor receptor." [GOC:mah, GOC:nln]


id: GO:0031860
name: telomeric 3' overhang formation
namespace: biological_process
def:
  "The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans." [PMID:16096639]


id: GO:0031861
name: prolactin-releasing peptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a prolactin-releasing peptide receptor." [GOC:mah, GOC:nln]


id: GO:0031864
name: EP1 subtype prostaglandin E2 receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln]


id: GO:0031865
name: EP2 subtype prostaglandin E2 receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an EP2 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln]


id: GO:0031866
name: EP3 subtype prostaglandin E2 receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an EP3 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln]


id: GO:0031867
name: EP4 subtype prostaglandin E2 receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an EP4 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln]


id: GO:0031868
name: prostaglandin F2-alpha receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a prostaglandin F2-alpha receptor." [GOC:mah, GOC:nln]


id: GO:0031871
name: proteinase activated receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a proteinase activated receptor." [GOC:mah, GOC:nln]


id: GO:0031872
name: type 1 proteinase activated receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 proteinase activated receptor." [GOC:mah, GOC:nln]


id: GO:0031873
name: type 2 proteinase activated receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 proteinase activated receptor." [GOC:mah, GOC:nln]


id: GO:0031874
name: type 3 proteinase activated receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 3 proteinase activated receptor." [GOC:mah, GOC:nln]


id: GO:0031875
name: type 4 proteinase activated receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 4 proteinase activated receptor." [GOC:mah, GOC:nln]


id: GO:0031878
name: type 1 somatostatin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 somatostatin receptor." [GOC:mah, GOC:nln]


id: GO:0031879
name: type 2 somatostatin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 somatostatin receptor." [GOC:mah, GOC:nln]


id: GO:0031880
name: type 3 somatostatin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 3 somatostatin receptor." [GOC:mah, GOC:nln]


id: GO:0031881
name: type 4 somatostatin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 4 somatostatin receptor." [GOC:mah, GOC:nln]


id: GO:0031882
name: type 5 somatostatin receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 5 somatostatin receptor." [GOC:mah, GOC:nln]


id: GO:0031884
name: type 1 member 1 taste receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 member 1 taste receptor." [GOC:mah, GOC:nln]


id: GO:0031885
name: type 1 member 2 taste receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 member 2 taste receptor." [GOC:mah, GOC:nln]


id: GO:0031886
name: type 1 member 3 taste receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 member 3 taste receptor." [GOC:mah, GOC:nln]


id: GO:0031887
name: lipid particle transport along microtubule
namespace: biological_process
def:
  "The directed movement of a lipid particle along a microtubule, mediated by motor proteins." [PMID:9491895]


id: GO:0031890
name: vasoactive intestinal polypeptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln]


id: GO:0031891
name: type 1 vasoactive intestinal polypeptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln]


id: GO:0031892
name: type 2 vasoactive intestinal polypeptide receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln]


id: GO:0031897
name: Tic complex
namespace: cellular_component
def:
  "The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane." [PMID:12180471, PMID:12393016]


id: GO:0031898
name: chromoplast envelope
namespace: cellular_component
def:
  "The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:pz]


id: GO:0031899
name: chromoplast inner membrane
namespace: cellular_component
def:
  "The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma." [GOC:pz]


id: GO:0031910
name: cytostome
namespace: cellular_component
def:
  "Stable, specialized structure for the ingestion of food by the cell into phagosomes." [PMID:10503189]


id: GO:0031911
name: cytoproct
namespace: cellular_component
def:
  "Stable, specialized structure for extrusion of waste by the cell into the surrounding medium." [PMID:10503189]


id: GO:0031912
name: oral apparatus
namespace: cellular_component
def:
  "Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems." [PMID:10503189]


id: GO:0031913
name: contractile vacuole pore
namespace: cellular_component
def:
  "Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium." [PMID:10503189]


id: GO:0031914
name: negative regulation of synaptic plasticity
namespace: biological_process
def:
  "A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah]


id: GO:0031915
name: positive regulation of synaptic plasticity
namespace: biological_process
def:
  "A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah]


id: GO:0031916
name: regulation of synaptic metaplasticity
namespace: biological_process
def:
  "A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594]


id: GO:0031917
name: negative regulation of synaptic metaplasticity
namespace: biological_process
def:
  "A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594]


id: GO:0031918
name: positive regulation of synaptic metaplasticity
namespace: biological_process
def:
  "A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594]


id: GO:0031919
name: vitamin B6 transport
namespace: biological_process
def:
  "The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0031920
name: pyridoxal transport
namespace: biological_process
def:
  "The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031921
name: pyridoxal phosphate transport
namespace: biological_process
def:
  "The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6." [GOC:mah]


id: GO:0031922
name: pyridoxamine transport
namespace: biological_process
def:
  "The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031923
name: pyridoxine transport
namespace: biological_process
def:
  "The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031924
name: vitamin B6 transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells." [GOC:mah]


id: GO:0031925
name: pyridoxal transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of pyridoxal across a membrane into, out of or within a cell, or between cells. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031926
name: pyridoxal phosphate transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of pyridoxal phosphate into, out of or within a cell, or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6." [GOC:mah]


id: GO:0031927
name: pyridoxamine transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of pyridoxamine into, out of or within a cell, or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031928
name: pyridoxine transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of pyridoxine across a membrane into, out of or within a cell, or between cells. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah]


id: GO:0031929
name: TOR signaling
namespace: biological_process
def:
  "A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors." [PMID:12372295]


id: GO:0031930
name: mitochondria-nucleus signaling pathway
namespace: biological_process
def:
  "A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function." [GOC:jh, PMID:15068799]


id: GO:0031931
name: TORC1 complex
namespace: cellular_component
def:
  "A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p." [GOC:jh, PMID:15780592, PMID:16469695, PMID:21548787]


id: GO:0031932
name: TORC2 complex
namespace: cellular_component
def:
  "A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p." [GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787]


id: GO:0031936
name: negative regulation of chromatin silencing
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing." [GOC:mah]


id: GO:0031937
name: positive regulation of chromatin silencing
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of chromatin silencing." [GOC:mah]


id: GO:0031938
name: regulation of chromatin silencing at telomere
namespace: biological_process
def:
  "Any process that affects the rate, extent or location of chromatin silencing at telomeres." [GOC:mah]


id: GO:0031939
name: negative regulation of chromatin silencing at telomere
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah]


id: GO:0031940
name: positive regulation of chromatin silencing at telomere
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah]


id: GO:0031942
name: i-AAA complex
namespace: cellular_component
def:
  "Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases." [PMID:16247555, PMID:16267274]


id: GO:0031943
name: regulation of glucocorticoid metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah]


id: GO:0031944
name: negative regulation of glucocorticoid metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah]


id: GO:0031945
name: positive regulation of glucocorticoid metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah]


id: GO:0031946
name: regulation of glucocorticoid biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah]


id: GO:0031947
name: negative regulation of glucocorticoid biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah]


id: GO:0031948
name: positive regulation of glucocorticoid biosynthetic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah]


id: GO:0031949
name: regulation of glucocorticoid catabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah]


id: GO:0031950
name: negative regulation of glucocorticoid catabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah]


id: GO:0031951
name: positive regulation of glucocorticoid catabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah]


id: GO:0031952
name: regulation of protein autophosphorylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues." [GOC:mah]


id: GO:0031953
name: negative regulation of protein autophosphorylation
namespace: biological_process
def:
  "Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues." [GOC:mah]


id: GO:0031954
name: positive regulation of protein autophosphorylation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues." [GOC:mah]


id: GO:0031955
name: short-chain fatty acid-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a short-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6." [CHEBI:26666, EC:6.2.1.3, GOC:mah]


id: GO:0031956
name: medium-chain fatty acid-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12." [CHEBI:59554, EC:6.2.1.3, GOC:mah]


id: GO:0031957
name: very long-chain fatty acid-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a very-long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [CHEBI:27283, EC:6.2.1.3, GOC:mah]


id: GO:0031958
name: corticosteroid receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724]


id: GO:0031959
name: mineralocorticoid receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724]


id: GO:0031960
name: response to corticosteroid
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." [GOC:mah, PMID:11027914]


id: GO:0031962
name: mineralocorticoid receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a mineralocorticoid receptor." [GOC:mah, PMID:12511169]


id: GO:0031963
name: cortisol receptor activity
namespace: molecular_function
def:
  "Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function." [GOC:mah, PMID:12511169]


id: GO:0031964
name: beta-alanyl-histamine hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine." [GOC:rc, PMID:16299587]


id: GO:0031965
name: nuclear membrane
namespace: cellular_component
def:
  "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz]


id: GO:0031966
name: mitochondrial membrane
namespace: cellular_component
def:
  "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:mah, NIF_Subcellular:sao1045389829]


id: GO:0031967
name: organelle envelope
namespace: cellular_component
def:
  "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz]


id: GO:0031968
name: organelle outer membrane
namespace: cellular_component
def:
  "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah]


id: GO:0031969
name: chloroplast membrane
namespace: cellular_component
def:
  "Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope." [GOC:mah, GOC:pz]


id: GO:0031974
name: membrane-enclosed lumen
namespace: cellular_component
def:
  "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah]


id: GO:0031975
name: envelope
namespace: cellular_component
def:
  "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz]


id: GO:0031984
name: organelle subcompartment
namespace: cellular_component
def:
  "A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle." [GOC:mah, GOC:pz]


id: GO:0031985
name: Golgi cisterna
namespace: cellular_component
def:
  "Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex." [GOC:mah]


id: GO:0031987
name: locomotion involved in locomotory behavior
namespace: biological_process
def:
  "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah]


id: GO:0031989
name: bombesin receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands." [GOC:mah]


id: GO:0031990
name: mRNA export from nucleus in response to heat stress
namespace: biological_process
def:
  "The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export." [GOC:mah, GOC:vw]


id: GO:0031991
name: regulation of actomyosin contractile ring contraction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0031992
name: energy transducer activity
namespace: molecular_function
def:
  "The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell." [GOC:go_curators]


id: GO:0031993
name: light transducer activity
namespace: molecular_function
def:
  "Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell." [GOC:mah, GOC:mlg]


id: GO:0031997
name: N-terminal myristoylation domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin." [GOC:dl, GOC:jsg, PMID:15632291]


id: GO:0031999
name: negative regulation of fatty acid beta-oxidation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah]


id: GO:0032000
name: positive regulation of fatty acid beta-oxidation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah]


id: GO:0032001
name: 1,4-alpha-glucan 6-alpha-glucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan." [EC:2.4.1.24]


id: GO:0032002
name: interleukin-28 receptor complex
namespace: cellular_component
def:
  "A protein complex that binds interleukin-28 and interleukin-29. Composed of two subunits, IL-28R alpha and IL-10R beta." [GOC:rph]


id: GO:0032005
name: signal transduction involved in conjugation with cellular fusion
namespace: biological_process
def:
  "The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:mah]


id: GO:0032007
name: negative regulation of TOR signaling
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling." [GOC:mah]


id: GO:0032009
name: early phagosome
namespace: cellular_component
def:
  "A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis." [GOC:mah, PMID:12388753]


id: GO:0032010
name: phagolysosome
namespace: cellular_component
def:
  "A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes." [GOC:mah, PMID:12388753]


id: GO:0032011
name: ARF protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state." [GOC:mah]


id: GO:0032012
name: regulation of ARF protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of ARF protein signal transduction." [GOC:mah]


id: GO:0032013
name: negative regulation of ARF protein signal transduction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction." [GOC:mah]


id: GO:0032014
name: positive regulation of ARF protein signal transduction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction." [GOC:mah]


id: GO:0032015
name: regulation of Ran protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Ran protein signal transduction." [GOC:mah]


id: GO:0032016
name: negative regulation of Ran protein signal transduction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction." [GOC:mah]


id: GO:0032017
name: positive regulation of Ran protein signal transduction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction." [GOC:mah]


id: GO:0032018
name: 2-methylbutanol:NADP oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+." [GOC:mah, PMID:12210903]


id: GO:0032019
name: mitochondrial cloud
namespace: cellular_component
def:
  "A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material." [PMID:6541166]


id: GO:0032021
name: NELF complex
namespace: cellular_component
def:
  "A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing." [PMID:12612062]


id: GO:0032022
name: multicellular pellicle formation
namespace: biological_process
def:
  "A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface." [GOC:ml]


id: GO:0032024
name: positive regulation of insulin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah]


id: GO:0032025
name: response to cobalt ion
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus." [GOC:mah]


id: GO:0032026
name: response to magnesium ion
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus." [GOC:mah]


id: GO:0032028
name: myosin head/neck binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain." [GOC:mah]


id: GO:0032029
name: myosin tail binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the tail region of a myosin heavy chain." [GOC:mah]


id: GO:0032031
name: myosin I head/neck binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the head/neck region of a myosin I heavy chain." [GOC:mah]


id: GO:0032032
name: myosin I tail binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the tail region of a myosin I heavy chain." [GOC:mah]


id: GO:0032034
name: myosin II head/neck binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the head/neck region of a myosin II heavy chain." [GOC:mah]


id: GO:0032035
name: myosin II tail binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the tail region of a myosin II heavy chain." [GOC:mah]


id: GO:0032039
name: integrator complex
namespace: cellular_component
def:
  "A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II." [PMID:16239144]


id: GO:0032040
name: small-subunit processome
namespace: cellular_component
def:
  "A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins." [GOC:krc, GOC:vw, PMID:12068309, PMID:12957375, PMID:15120992, PMID:15590835]


id: GO:0032041
name: NAD-dependent histone deacetylase activity (H3-K14 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein." [EC:3.5.1.17, RHEA:24551]


id: GO:0032044
name: DSIF complex
namespace: cellular_component
def:
  "A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes." [PMID:12242279, PMID:12653964, PMID:12676794, PMID:16581788, PMID:19460865]


id: GO:0032045
name: guanyl-nucleotide exchange factor complex
namespace: cellular_component
def:
  "A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase." [GOC:mah]


id: GO:0032046
name: micropexophagy-specific membrane apparatus
namespace: cellular_component
def:
  "A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole." [PMID:15563611]


id: GO:0032047
name: mitosome
namespace: cellular_component
def:
  "A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria." [GOC:giardia, PMID:10361303, PMID:14614504, PMID:24316280]


id: GO:0032048
name: cardiolipin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol." [CHEBI:28494, GOC:mah]


id: GO:0032049
name: cardiolipin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol." [CHEBI:28494, GOC:mah]


id: GO:0032052
name: bile acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:rph]


id: GO:0032053
name: ciliary basal body organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum)." [GOC:cilia, GOC:dph, GOC:jl, GOC:mah, PMID:9889124]


id: GO:0032055
name: negative regulation of translation in response to stress
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah]


id: GO:0032056
name: positive regulation of translation in response to stress
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah]


id: GO:0032057
name: negative regulation of translational initiation in response to stress
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah]


id: GO:0032058
name: positive regulation of translational initiation in response to stress
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah]


id: GO:0032059
name: bleb
namespace: cellular_component
def:
  "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, http://en.wikipedia.org/wiki/Bleb_(cell_biology), PMID:12083798, PMID:16624291]


id: GO:0032060
name: bleb assembly
namespace: biological_process
def:
  "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, http://en.wikipedia.org/wiki/Bleb_(cell_biology), PMID:12083798, PMID:16624291]


id: GO:0032061
name: negative regulation of translation in response to osmotic stress
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah]


id: GO:0032062
name: positive regulation of translation in response to osmotic stress
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah]


id: GO:0032063
name: negative regulation of translational initiation in response to osmotic stress
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah]


id: GO:0032064
name: positive regulation of translational initiation in response to osmotic stress
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah]


id: GO:0032065
name: cortical protein anchoring
namespace: biological_process
def:
  "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." [GOC:vw]


id: GO:0032067
name: Type IV site-specific deoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated)." [PMID:12654995]


id: GO:0032068
name: Type IV site-specific deoxyribonuclease complex
namespace: cellular_component
def:
  "A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation." [PMID:12654995]


id: GO:0032069
name: regulation of nuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]


id: GO:0032070
name: regulation of deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]


id: GO:0032071
name: regulation of endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah]


id: GO:0032072
name: regulation of restriction endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mah]


id: GO:0032073
name: negative regulation of restriction endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mah]


id: GO:0032074
name: negative regulation of nuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]


id: GO:0032075
name: positive regulation of nuclease activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]


id: GO:0032076
name: negative regulation of deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]


id: GO:0032077
name: positive regulation of deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]


id: GO:0032078
name: negative regulation of endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah]


id: GO:0032079
name: positive regulation of endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah]


id: GO:0032080
name: negative regulation of Type I site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of Type I restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032081
name: negative regulation of Type II site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of Type II restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032082
name: negative regulation of Type III site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of Type III restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032083
name: negative regulation of Type IV site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that stops or reduces the rate of Type IV restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032084
name: regulation of Type I site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a Type I restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah]


id: GO:0032085
name: regulation of Type II site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a Type II restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah]


id: GO:0032086
name: regulation of Type III site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a Type III restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah]


id: GO:0032087
name: regulation of Type IV site-specific deoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a Type IV restriction endodeoxyribonuclease activity." [GOC:mah]


id: GO:0032088
name: negative regulation of NF-kappaB transcription factor activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb]


id: GO:0032089
name: NACHT domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs." [GOC:rl]


id: GO:0032090
name: Pyrin domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain." [GOC:rl]


id: GO:0032091
name: negative regulation of protein binding
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." [GOC:mah]


id: GO:0032092
name: positive regulation of protein binding
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of protein binding." [GOC:mah]


id: GO:0032093
name: SAM domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes." [GOC:mcc, PMID:16337230]


id: GO:0032094
name: response to food
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." [GOC:add, ISBN:0721601464]


id: GO:0032095
name: regulation of response to food
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a response to a food stimulus." [GOC:add]


id: GO:0032096
name: negative regulation of response to food
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus." [GOC:add]


id: GO:0032097
name: positive regulation of response to food
namespace: biological_process
def:
  "Any process that activates, maintains, or increases the rate of a response to a food stimulus." [GOC:add]


id: GO:0032101
name: regulation of response to external stimulus
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah]


id: GO:0032102
name: negative regulation of response to external stimulus
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah]


id: GO:0032103
name: positive regulation of response to external stimulus
namespace: biological_process
def:
  "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah]


id: GO:0032104
name: regulation of response to extracellular stimulus
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus." [GOC:mah]


id: GO:0032105
name: negative regulation of response to extracellular stimulus
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus." [GOC:mah]


id: GO:0032106
name: positive regulation of response to extracellular stimulus
namespace: biological_process
def:
  "Any process that activates, maintains or increases the rate of a response to an extracellular stimulus." [GOC:mah]


id: GO:0032107
name: regulation of response to nutrient levels
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a response to nutrient levels." [GOC:mah]


id: GO:0032108
name: negative regulation of response to nutrient levels
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels." [GOC:mah]


id: GO:0032109
name: positive regulation of response to nutrient levels
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of a response to nutrient levels." [GOC:mah]


id: GO:0032110
name: regulation of protein histidine kinase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of protein histidine kinase activity." [GOC:mah]


id: GO:0032112
name: negative regulation of protein histidine kinase activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity." [GOC:mah]


id: GO:0032113
name: regulation of carbohydrate phosphatase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate." [GOC:mah]


id: GO:0032114
name: regulation of glucose-6-phosphatase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate." [GOC:kp]


id: GO:0032115
name: sorbose reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction." [EC:1.1.1.289, RHEA:14612]


id: GO:0032116
name: SMC loading complex
namespace: cellular_component
def:
  "A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved." [GOC:curators, GOC:vw, PMID:10882066]


id: GO:0032117
name: horsetail-astral microtubule array
namespace: cellular_component
def:
  "An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement." [GOC:mah, PMID:16111942]


id: GO:0032118
name: horsetail-astral microtubule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis." [GOC:mah]


id: GO:0032119
name: sequestering of zinc ion
namespace: biological_process
def:
  "The process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:mah]


id: GO:0032120
name: ascospore-type prospore membrane assembly
namespace: biological_process
def:
  "The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed." [GOC:clt]


id: GO:0032121
name: meiotic attachment of telomeric heterochromatin to spindle pole body
namespace: biological_process
def:
  "The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation." [GOC:pr, PMID:16615890]


id: GO:0032122
name: oral apparatus organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans." [PMID:10503189, PMID:6414830]


id: GO:0032123
name: deep fiber
namespace: cellular_component
def:
  "Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm." [PMID:10503189]


id: GO:0032124
name: macronucleus organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus." [GOC:dph, GOC:jl, GOC:mah, PMID:10503190]


id: GO:0032125
name: micronucleus organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus." [GOC:dph, GOC:jl, GOC:mah, PMID:10503190]


id: GO:0032126
name: eisosome
namespace: cellular_component
def:
  "A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization." [GOC:al, GOC:vw, PMID:16496001, PMID:22368779]


id: GO:0032128
name: flocculation via extracellular polymer
namespace: biological_process
def:
  "Non-sexual aggregation of single-celled organisms mediated by polymers (polysaccharides, proteins, and/or nucleic acids) secreted into the extracellular environment." [DOI:10.1007/s002530051351, GOC:mah, PMID:14538073]


id: GO:0032129
name: histone deacetylase activity (H3-K9 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein." [EC:3.5.1.17, RHEA:24551]


id: GO:0032130
name: medial membrane band assembly
namespace: biological_process
def:
  "The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring." [PMID:15517003]


id: GO:0032132
name: O6-alkylguanine-DNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with O6-alkylguanine adducts in DNA." [GOC:mah, PMID:16679453]


id: GO:0032133
name: chromosome passenger complex
namespace: cellular_component
def:
  "A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin." [GOC:vw, PMID:16824200, PMID:19570910]


id: GO:0032135
name: DNA insertion or deletion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions." [GOC:vk]


id: GO:0032136
name: adenine/cytosine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair." [GOC:vk]


id: GO:0032137
name: guanine/thymine mispair binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair." [GOC:vk]


id: GO:0032138
name: single base insertion or deletion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion." [GOC:vk]


id: GO:0032139
name: dinucleotide insertion or deletion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion." [GOC:vk]


id: GO:0032140
name: single adenine insertion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine." [GOC:mah, GOC:vk]


id: GO:0032141
name: single cytosine insertion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine." [GOC:mah, GOC:vk]


id: GO:0032142
name: single guanine insertion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine." [GOC:mah, GOC:vk]


id: GO:0032143
name: single thymine insertion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine." [GOC:mah, GOC:vk]


id: GO:0032144
name: 4-aminobutyrate transaminase complex
namespace: cellular_component
def:
  "A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity." [GOC:mah, PMID:15528998]


id: GO:0032146
name: thiosulfate transmembrane-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in)." [GOC:mlg]


id: GO:0032149
name: response to rhamnose
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus." [GOC:mlg]


id: GO:0032150
name: ubiquinone biosynthetic process from chorismate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate." [GOC:mah, PMID:11583838]


id: GO:0032151
name: mitotic septin complex
namespace: cellular_component
def:
  "A heterooligomeric septin complex that acts during mitotic cell division." [GOC:krc, PMID:16009555]


id: GO:0032152
name: meiotic septin complex
namespace: cellular_component
def:
  "A heterooligomeric septin complex that acts during meiotic cell division." [GOC:krc, PMID:16009555]


id: GO:0032153
name: cell division site
namespace: cellular_component
def:
  "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles." [GOC:bf, GOC:imk, GOC:krc, GOC:ns, PMID:12101122, PMID:15380095, PMID:16983191, PMID:18165305]


id: GO:0032154
name: cleavage furrow
namespace: cellular_component
def:
  "In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists." [ISBN:0805319409]


id: GO:0032155
name: cell division site part
namespace: cellular_component
def:
  "Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell." [GOC:mah]


id: GO:0032156
name: septin cytoskeleton
namespace: cellular_component
def:
  "The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes." [GOC:mah]


id: GO:0032157
name: prospore contractile ring
namespace: cellular_component
def:
  "A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis." [GOC:krc, PMID:16009555]


id: GO:0032158
name: septin band
namespace: cellular_component
def:
  "A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:krc, PMID:16151244]


id: GO:0032159
name: septin cap
namespace: cellular_component
def:
  "A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244]


id: GO:0032160
name: septin filament array
namespace: cellular_component
def:
  "Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans." [GOC:krc, PMID:16151244]


id: GO:0032161
name: cleavage apparatus septin structure
namespace: cellular_component
def:
  "Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis." [GOC:krc, PMID:12101122, PMID:15774761, PMID:16009555]


id: GO:0032162
name: mating projection septin band
namespace: cellular_component
def:
  "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection)." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032163
name: hyphal septin band
namespace: cellular_component
def:
  "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032164
name: hyphal septin cap
namespace: cellular_component
def:
  "A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244]


id: GO:0032165
name: prospore septin filament array
namespace: cellular_component
def:
  "Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation." [GOC:krc, PMID:16151244]


id: GO:0032166
name: chlamydospore septin filament array
namespace: cellular_component
def:
  "Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation." [GOC:krc, PMID:16151244]


id: GO:0032167
name: obsolete septin patch
namespace: cellular_component
def:
  "OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis." [PMID:16009555]


id: GO:0032168
name: hyphal septin ring
namespace: cellular_component
def:
  "A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032169
name: prospore septin ring
namespace: cellular_component
def:
  "A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032170
name: pseudohyphal septin ring
namespace: cellular_component
def:
  "A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032171
name: germ tube septin cap
namespace: cellular_component
def:
  "A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244]


id: GO:0032172
name: germ tube septin ring
namespace: cellular_component
def:
  "A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, PMID:16151244]


id: GO:0032173
name: septin collar
namespace: cellular_component
def:
  "A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell." [GOC:krc, PMID:16009555, PMID:16151244]


id: GO:0032174
name: cellular bud neck septin collar
namespace: cellular_component
def:
  "A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck." [GOC:krc, PMID:16009555]


id: GO:0032175
name: mating projection septin ring
namespace: cellular_component
def:
  "A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip." [GOC:krc, GOC:mah, PMID:16151244]


id: GO:0032176
name: split septin rings
namespace: cellular_component
def:
  "A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well." [GOC:krc, PMID:16009555, PMID:16151244]


id: GO:0032177
name: cellular bud neck split septin rings
namespace: cellular_component
def:
  "Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated." [GOC:krc, PMID:16009555]


id: GO:0032178
name: medial membrane band
namespace: cellular_component
def:
  "A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum." [PMID:15517003]


id: GO:0032180
name: ubiquinone biosynthetic process from tyrosine
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate." [GOC:mah, PMID:11583838]


id: GO:0032181
name: dinucleotide repeat insertion binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats." [GOC:mah, GOC:vk]


id: GO:0032182
name: ubiquitin-like protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein." [GOC:mah]


id: GO:0032184
name: SUMO polymer binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO." [GOC:mah]


id: GO:0032185
name: septin cytoskeleton organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins." [GOC:dph, GOC:jl, GOC:mah]


id: GO:0032186
name: cellular bud neck septin ring organization
namespace: biological_process
def:
  "Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck." [GOC:mah]


id: GO:0032187
name: actomyosin contractile ring localization
namespace: biological_process
def:
  "The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle." [GOC:mah]


id: GO:0032188
name: establishment of actomyosin contractile ring localization
namespace: biological_process
def:
  "The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis." [GOC:mah]


id: GO:0032189
name: maintenance of actomyosin contractile ring localization
namespace: biological_process
def:
  "Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere." [GOC:mah]


id: GO:0032190
name: acrosin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities." [GOC:mah, PMID:12398221]


id: GO:0032193
name: ubiquinone biosynthetic process via 2-polyprenylphenol
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol." [GOC:mah, PMID:11583838]


id: GO:0032194
name: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate." [GOC:mah, PMID:11583838]


id: GO:0032195
name: post-lysosomal vacuole
namespace: cellular_component
def:
  "A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis." [GOC:pf, PMID:9276759, PMID:9394012]


id: GO:0032196
name: transposition
namespace: biological_process
def:
  "Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites." [GOC:jp, ISBN:1555812090]


id: GO:0032197
name: transposition, RNA-mediated
namespace: biological_process
def:
  "Any process involved in a type of transpositional recombination which occurs via an RNA intermediate." [GOC:jp, ISBN:1555812090]


id: GO:0032198
name: MITE transposition
namespace: biological_process
def:
  "Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs)." [GOC:jp, ISBN:1555812090]


id: GO:0032200
name: telomere organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins." [GOC:dph, GOC:jl, GOC:mah]


id: GO:0032201
name: telomere maintenance via semi-conservative replication
namespace: biological_process
def:
  "The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication." [GOC:vw, PMID:16598261]


id: GO:0032202
name: telomere assembly
namespace: biological_process
def:
  "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins." [GOC:mah, GOC:ns, PMID:11902675, PMID:8622671]


id: GO:0032203
name: telomere formation via telomerase
namespace: biological_process
def:
  "A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme." [GOC:cjm, GOC:ns, PMID:11902675, PMID:8622671]


id: GO:0032204
name: regulation of telomere maintenance
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah]


id: GO:0032205
name: negative regulation of telomere maintenance
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah]


id: GO:0032206
name: positive regulation of telomere maintenance
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah]


id: GO:0032207
name: regulation of telomere maintenance via recombination
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah]


id: GO:0032208
name: negative regulation of telomere maintenance via recombination
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah]


id: GO:0032209
name: positive regulation of telomere maintenance via recombination
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah]


id: GO:0032210
name: regulation of telomere maintenance via telomerase
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah]


id: GO:0032211
name: negative regulation of telomere maintenance via telomerase
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah]


id: GO:0032212
name: positive regulation of telomere maintenance via telomerase
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah]


id: GO:0032213
name: regulation of telomere maintenance via semi-conservative replication
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah]


id: GO:0032214
name: negative regulation of telomere maintenance via semi-conservative replication
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah]


id: GO:0032215
name: positive regulation of telomere maintenance via semi-conservative replication
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah]


id: GO:0032216
name: glucosaminyl-phosphotidylinositol O-acyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: glucosaminyl-phosphotidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phosphotidylinositol + CoA." [Reactome:REACT_1049.1]


id: GO:0032217
name: riboflavin transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of riboflavin into, out of or within a cell, or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239]


id: GO:0032218
name: riboflavin transport
namespace: biological_process
def:
  "The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239]


id: GO:0032219
name: cell wall macromolecule catabolic process involved in cytogamy
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy." [GOC:mah]


id: GO:0032220
name: plasma membrane fusion involved in cytogamy
namespace: biological_process
def:
  "The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy." [GOC:mah]


id: GO:0032221
name: Rpd3S complex
namespace: cellular_component
def:
  "A eukaryotically conserved histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species)." [GOC:vw, PMID:12773392, PMID:17450151]


id: GO:0032222
name: regulation of synaptic transmission, cholinergic
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]


id: GO:0032223
name: negative regulation of synaptic transmission, cholinergic
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]


id: GO:0032224
name: positive regulation of synaptic transmission, cholinergic
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]


id: GO:0032225
name: regulation of synaptic transmission, dopaminergic
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah]


id: GO:0032226
name: positive regulation of synaptic transmission, dopaminergic
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah]


id: GO:0032227
name: negative regulation of synaptic transmission, dopaminergic
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah]


id: GO:0032228
name: regulation of synaptic transmission, GABAergic
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah]


id: GO:0032229
name: negative regulation of synaptic transmission, GABAergic
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah]


id: GO:0032230
name: positive regulation of synaptic transmission, GABAergic
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah]


id: GO:0032231
name: regulation of actin filament bundle assembly
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]


id: GO:0032232
name: negative regulation of actin filament bundle assembly
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]


id: GO:0032233
name: positive regulation of actin filament bundle assembly
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]


id: GO:0032234
name: obsolete regulation of calcium ion transport via store-operated calcium channel activity
namespace: biological_process
def:
  "OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901]


id: GO:0032235
name: obsolete negative regulation of calcium ion transport via store-operated calcium channel activity
namespace: biological_process
def:
  "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901]


id: GO:0032236
name: obsolete positive regulation of calcium ion transport via store-operated calcium channel activity
namespace: biological_process
def:
  "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901]


id: GO:0032238
name: adenosine transport
namespace: biological_process
def:
  "The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032239
name: regulation of nucleobase-containing compound transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032240
name: negative regulation of nucleobase-containing compound transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032241
name: positive regulation of nucleobase-containing compound transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032242
name: regulation of nucleoside transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032243
name: negative regulation of nucleoside transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032244
name: positive regulation of nucleoside transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032245
name: regulation of purine nucleoside transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032246
name: regulation of pyrimidine nucleoside transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032247
name: negative regulation of purine nucleoside transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032248
name: positive regulation of purine nucleoside transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032249
name: regulation of adenosine transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032250
name: negative regulation of adenosine transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032251
name: positive regulation of adenosine transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032252
name: secretory granule localization
namespace: biological_process
def:
  "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah]


id: GO:0032253
name: dense core granule localization
namespace: biological_process
def:
  "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah]


id: GO:0032255
name: maintenance of secretory granule location
namespace: biological_process
def:
  "Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032257
name: maintenance of dense core granule location
namespace: biological_process
def:
  "Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032258
name: CVT pathway
namespace: biological_process
def:
  "A constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast." [PMID:12865942, PMID:15659643]


id: GO:0032260
namespace: biological_process
name:
  response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance

def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen." [GOC:mah]


id: GO:0032261
name: purine nucleotide salvage
namespace: biological_process
def:
  "Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis." [GOC:jp]


id: GO:0032262
name: pyrimidine nucleotide salvage
namespace: biological_process
def:
  "Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis." [GOC:mah]


id: GO:0032263
name: GMP salvage
namespace: biological_process
def:
  "Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah]


id: GO:0032264
name: IMP salvage
namespace: biological_process
def:
  "Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah]


id: GO:0032265
name: XMP salvage
namespace: biological_process
def:
  "Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah]


id: GO:0032266
name: phosphatidylinositol-3-phosphate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position." [GOC:bf, PMID:10209156, PMID:11395417, PMID:11557775]


id: GO:0032267
name: tRNA(Ile)-lysidine synthase activity
namespace: molecular_function
def:
  "Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine." [PMID:14527414]


id: GO:0032268
name: regulation of cellular protein metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah]


id: GO:0032269
name: negative regulation of cellular protein metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah]


id: GO:0032270
name: positive regulation of cellular protein metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah]


id: GO:0032271
name: regulation of protein polymerization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]


id: GO:0032272
name: negative regulation of protein polymerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]


id: GO:0032273
name: positive regulation of protein polymerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]


id: GO:0032274
name: gonadotropin secretion
namespace: biological_process
def:
  "The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone." [GOC:mah, ISBN:0721662544]


id: GO:0032275
name: luteinizing hormone secretion
namespace: biological_process
def:
  "The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary." [ISBN:0198506732]


id: GO:0032276
name: regulation of gonadotropin secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah]


id: GO:0032277
name: negative regulation of gonadotropin secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah]


id: GO:0032278
name: positive regulation of gonadotropin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah]


id: GO:0032279
name: asymmetric synapse
namespace: cellular_component
def:
  "A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density." [GOC:dgh, GOC:ef]


id: GO:0032280
name: symmetric synapse
namespace: cellular_component
def:
  "A type of synapse occurring primarily on dendrite shafts and neuronal cell bodies. Symmetric synapses involve axons containing clusters of predominantly flattened or elongated vesicles and do not contain a prominent postsynaptic density." [GOC:dgh, GOC:ef]


id: GO:0032281
name: AMPA glutamate receptor complex
namespace: cellular_component
def:
  "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus." [GOC:ef]


id: GO:0032286
name: central nervous system myelin maintenance
namespace: biological_process
def:
  "The process in which the structure and material content of mature central nervous system myelin is kept in a functional state." [GOC:dgh]


id: GO:0032287
name: peripheral nervous system myelin maintenance
namespace: biological_process
def:
  "The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state." [GOC:dgh]


id: GO:0032288
name: myelin assembly
namespace: biological_process
def:
  "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system." [GOC:dgh, GOC:dph, GOC:tb]


id: GO:0032289
name: central nervous system myelin formation
namespace: biological_process
def:
  "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system." [GOC:dgh]


id: GO:0032290
name: peripheral nervous system myelin formation
namespace: biological_process
def:
  "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system." [GOC:dgh]


id: GO:0032291
name: axon ensheathment in central nervous system
namespace: biological_process
def:
  "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh]


id: GO:0032292
name: peripheral nervous system axon ensheathment
namespace: biological_process
def:
  "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh]


id: GO:0032293
name: non-myelinated axon ensheathment in central nervous system
namespace: biological_process
def:
  "The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system." [GOC:dgh]


id: GO:0032294
name: peripheral nervous system non-myelinated axon ensheathment
namespace: biological_process
def:
  "The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons." [GOC:dgh]


id: GO:0032297
name: negative regulation of DNA-dependent DNA replication initiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication." [GOC:mah]


id: GO:0032298
name: positive regulation of DNA-dependent DNA replication initiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication." [GOC:mah]


id: GO:0032299
name: ribonuclease H2 complex
namespace: cellular_component
def:
  "A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p." [GOC:mah, PMID:14734815]


id: GO:0032301
name: MutSalpha complex
namespace: cellular_component
def:
  "A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6." [PMID:11005803]


id: GO:0032302
name: MutSbeta complex
namespace: cellular_component
def:
  "A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3." [PMID:11005803]


id: GO:0032303
name: regulation of icosanoid secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah]


id: GO:0032304
name: negative regulation of icosanoid secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah]


id: GO:0032305
name: positive regulation of icosanoid secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah]


id: GO:0032306
name: regulation of prostaglandin secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah]


id: GO:0032307
name: negative regulation of prostaglandin secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah]


id: GO:0032308
name: positive regulation of prostaglandin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah]


id: GO:0032309
name: icosanoid secretion
namespace: biological_process
def:
  "The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue." [GOC:mah]


id: GO:0032310
name: prostaglandin secretion
namespace: biological_process
def:
  "The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue." [GOC:mah]


id: GO:0032311
name: angiogenin-PRI complex
namespace: cellular_component
def:
  "A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis." [PMID:2706246, PMID:3470787]


id: GO:0032322
name: ubiquinone catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme." [GOC:mah]


id: GO:0032324
name: molybdopterin cofactor biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [GOC:mah]


id: GO:0032325
name: molybdopterin cofactor catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [GOC:mah]


id: GO:0032326
name: Mo-molybdopterin cofactor catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands." [GOC:mah]


id: GO:0032327
name: W-molybdopterin cofactor catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands." [GOC:mah]


id: GO:0032328
name: alanine transport
namespace: biological_process
def:
  "The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032329
name: serine transport
namespace: biological_process
def:
  "The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032330
name: regulation of chondrocyte differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]


id: GO:0032331
name: negative regulation of chondrocyte differentiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]


id: GO:0032332
name: positive regulation of chondrocyte differentiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]


id: GO:0032333
name: activin secretion
namespace: biological_process
def:
  "The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone." [GOC:mah]


id: GO:0032334
name: inhibin secretion
namespace: biological_process
def:
  "The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone." [GOC:mah]


id: GO:0032335
name: regulation of activin secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah]


id: GO:0032336
name: negative regulation of activin secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah]


id: GO:0032337
name: positive regulation of activin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah]


id: GO:0032338
name: regulation of inhibin secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah]


id: GO:0032339
name: negative regulation of inhibin secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah]


id: GO:0032340
name: positive regulation of inhibin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah]


id: GO:0032341
name: aldosterone metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843]


id: GO:0032342
name: aldosterone biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843]


id: GO:0032343
name: aldosterone catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843]


id: GO:0032344
name: regulation of aldosterone metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah]


id: GO:0032345
name: negative regulation of aldosterone metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah]


id: GO:0032346
name: positive regulation of aldosterone metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah]


id: GO:0032347
name: regulation of aldosterone biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah]


id: GO:0032348
name: negative regulation of aldosterone biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah]


id: GO:0032349
name: positive regulation of aldosterone biosynthetic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah]


id: GO:0032350
name: regulation of hormone metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah]


id: GO:0032351
name: negative regulation of hormone metabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah]


id: GO:0032352
name: positive regulation of hormone metabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah]


id: GO:0032353
name: negative regulation of hormone biosynthetic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai]


id: GO:0032354
name: response to follicle-stimulating hormone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus." [GOC:mah]


id: GO:0032355
name: response to estradiol
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." [GOC:mah, ISBN:0911910123]


id: GO:0032361
name: pyridoxal phosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6." [GOC:mah]


id: GO:0032362
name: obsolete FAD catabolic process
namespace: biological_process
def:
  "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide." [CHEBI:16238, GOC:mah]


id: GO:0032363
name: FMN catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase." [GOC:mah]


id: GO:0032364
name: oxygen homeostasis
namespace: biological_process
def:
  "A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell." [GOC:rph]


id: GO:0032368
name: regulation of lipid transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032369
name: negative regulation of lipid transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032370
name: positive regulation of lipid transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032371
name: regulation of sterol transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032372
name: negative regulation of sterol transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032373
name: positive regulation of sterol transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032374
name: regulation of cholesterol transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032375
name: negative regulation of cholesterol transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032376
name: positive regulation of cholesterol transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032377
name: regulation of intracellular lipid transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]


id: GO:0032378
name: negative regulation of intracellular lipid transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]


id: GO:0032379
name: positive regulation of intracellular lipid transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]


id: GO:0032380
name: regulation of intracellular sterol transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah]


id: GO:0032381
name: negative regulation of intracellular sterol transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah]


id: GO:0032382
name: positive regulation of intracellular sterol transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah]


id: GO:0032383
name: regulation of intracellular cholesterol transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah]


id: GO:0032384
name: negative regulation of intracellular cholesterol transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah]


id: GO:0032385
name: positive regulation of intracellular cholesterol transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah]


id: GO:0032386
name: regulation of intracellular transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]


id: GO:0032387
name: negative regulation of intracellular transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]


id: GO:0032388
name: positive regulation of intracellular transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]


id: GO:0032389
name: MutLalpha complex
namespace: cellular_component
def:
  "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2." [GOC:vk]


id: GO:0032390
name: MutLbeta complex
namespace: cellular_component
def:
  "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1." [GOC:vk]


id: GO:0032391
name: photoreceptor connecting cilium
namespace: cellular_component
def:
  "A nonmotile primary cilium that has a 9+0 microtubule array and forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments." [PMID:15917207, PMID:8718680]


id: GO:0032392
name: DNA geometric change
namespace: biological_process
def:
  "The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases." [GOC:mah]


id: GO:0032393
name: MHC class I receptor activity
namespace: molecular_function
def:
  "Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149]


id: GO:0032394
name: MHC class Ib receptor activity
namespace: molecular_function
def:
  "Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, GOC:signaling, ISBN:0781735149]


id: GO:0032395
name: MHC class II receptor activity
namespace: molecular_function
def:
  "Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149]


id: GO:0032396
name: inhibitory MHC class I receptor activity
namespace: molecular_function
def:
  "Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, PMID:11858820, PMID:9368779, PMID:9597134]


id: GO:0032397
name: activating MHC class I receptor activity
namespace: molecular_function
def:
  "Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte." [GOC:add, PMID:11858820, PMID:9597134]


id: GO:0032398
name: MHC class Ib protein complex
namespace: cellular_component
def:
  "A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, ISBN:0781735149, PMID:15928678]


id: GO:0032399
name: HECT domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein." [GOC:mah, Pfam:PF00632]


id: GO:0032400
name: melanosome localization
namespace: biological_process
def:
  "Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell." [GOC:ln]


id: GO:0032402
name: melanosome transport
namespace: biological_process
def:
  "The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ln]


id: GO:0032403
name: protein complex binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:mah]


id: GO:0032415
name: regulation of sodium:proton antiporter activity
namespace: biological_process
def:
  "Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah, GOC:mtg_transport]


id: GO:0032416
name: negative regulation of sodium:proton antiporter activity
namespace: biological_process
def:
  "Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah]


id: GO:0032417
name: positive regulation of sodium:proton antiporter activity
namespace: biological_process
def:
  "Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah]


id: GO:0032418
name: lysosome localization
namespace: biological_process
def:
  "Any process in which a lysosome is transported to, and/or maintained in, a specific location." [GOC:mah]


id: GO:0032419
name: extrinsic component of lysosome membrane
namespace: cellular_component
def:
  "The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah]


id: GO:0032420
name: stereocilium
namespace: cellular_component
def:
  "An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles." [GOC:ecd, PMID:15661519, PMID:7840137]


id: GO:0032421
name: stereocilium bundle
namespace: cellular_component
def:
  "A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes." [GOC:ecd, PMID:15661519, PMID:7840137]


id: GO:0032422
name: purine-rich negative regulatory element binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes." [GOC:mah, PMID:9819411]


id: GO:0032424
name: negative regulation of mismatch repair
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair." [GOC:vk]


id: GO:0032425
name: positive regulation of mismatch repair
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of mismatch repair." [GOC:vk]


id: GO:0032426
name: stereocilium tip
namespace: cellular_component
def:
  "A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane." [GOC:ecd, PMID:17021180]


id: GO:0032427
name: GBD domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac." [GOC:mah, GOC:pg, PMID:9119069]


id: GO:0032428
name: beta-N-acetylgalactosaminidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides." [EC:3.2.1.53]


id: GO:0032432
name: actin filament bundle
namespace: cellular_component
def:
  "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah]


id: GO:0032434
name: regulation of proteasomal ubiquitin-dependent protein catabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah]


id: GO:0032435
name: negative regulation of proteasomal ubiquitin-dependent protein catabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah]


id: GO:0032436
name: positive regulation of proteasomal ubiquitin-dependent protein catabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah]


id: GO:0032437
name: cuticular plate
namespace: cellular_component
def:
  "A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted." [PMID:12485990, PMID:2592408, PMID:8071151]


id: GO:0032438
name: melanosome organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored." [GOC:vk]


id: GO:0032439
name: endosome localization
namespace: biological_process
def:
  "Any process in which endosomes are transported to, and/or maintained in, a specific location within the cell." [GOC:ecd]


id: GO:0032440
name: 2-alkenal reductase [NAD(P)] activity
namespace: molecular_function
def:
  "Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+." [EC:1.3.1.74, PMID:16299173]


id: GO:0032441
name: pheophorbide a oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O." [PMID:14657372, PMID:16448336]


id: GO:0032442
name: phenylcoumaran benzylic ether reductase activity
namespace: molecular_function
def:
  "Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+." [PMID:11030549, PMID:13129921]


id: GO:0032443
name: regulation of ergosterol biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol." [GOC:mah]


id: GO:0032444
name: activin responsive factor complex
namespace: cellular_component
def:
  "A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor." [PMID:12374795, PMID:9288972]


id: GO:0032446
name: protein modification by small protein conjugation
namespace: biological_process
def:
  "A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein." [GOC:mah]


id: GO:0032448
name: DNA hairpin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences." [GOC:mah, ISBN:0198506732]


id: GO:0032449
name: CBM complex
namespace: cellular_component
def:
  "A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation." [PMID:12909454]


id: GO:0032453
name: histone demethylase activity (H3-K4 specific)
namespace: molecular_function
def:
  "Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein." [GOC:mah]


id: GO:0032454
name: histone demethylase activity (H3-K9 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein." [PMID:16362057]


id: GO:0032455
name: nerve growth factor processing
namespace: biological_process
def:
  "The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor." [GOC:mah, PMID:8615794]


id: GO:0032456
name: endocytic recycling
namespace: biological_process
def:
  "The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635]


id: GO:0032457
name: fast endocytic recycling
namespace: biological_process
def:
  "The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635]


id: GO:0032458
name: slow endocytic recycling
namespace: biological_process
def:
  "The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635]


id: GO:0032460
name: negative regulation of protein oligomerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization." [GOC:mah]


id: GO:0032461
name: positive regulation of protein oligomerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of protein oligomerization." [GOC:mah]


id: GO:0032462
name: regulation of protein homooligomerization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of protein homooligomerization." [GOC:mah]


id: GO:0032463
name: negative regulation of protein homooligomerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization." [GOC:mah]


id: GO:0032464
name: positive regulation of protein homooligomerization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of protein homooligomerization." [GOC:mah]


id: GO:0032465
name: regulation of cytokinesis
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:mah]


id: GO:0032466
name: negative regulation of cytokinesis
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah]


id: GO:0032467
name: positive regulation of cytokinesis
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah]


id: GO:0032468
name: Golgi calcium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings." [GOC:mah]


id: GO:0032469
name: endoplasmic reticulum calcium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings." [GOC:mah]


id: GO:0032470
name: positive regulation of endoplasmic reticulum calcium ion concentration
namespace: biological_process
def:
  "Any process that increases the concentration of calcium ions in the endoplasmic reticulum." [GOC:mah]


id: GO:0032471
name: negative regulation of endoplasmic reticulum calcium ion concentration
namespace: biological_process
def:
  "Any process that decreases the concentration of calcium ions in the endoplasmic reticulum." [GOC:mah]


id: GO:0032472
name: Golgi calcium ion transport
namespace: biological_process
def:
  "The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus." [GOC:mah]


id: GO:0032474
name: otolith morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of an otolith are generated and organized." [GOC:dgh]


id: GO:0032475
name: otolith formation
namespace: biological_process
def:
  "The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dgh]


id: GO:0032476
name: decaprenyl diphosphate synthase complex
namespace: cellular_component
def:
  "A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [GOC:mah, PMID:14519123]


id: GO:0032477
name: homodimeric decaprenyl diphosphate synthase complex
namespace: cellular_component
def:
  "A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [PMID:14519123]


id: GO:0032478
name: heterotetrameric decaprenyl diphosphate synthase complex
namespace: cellular_component
def:
  "A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1." [PMID:14519123]


id: GO:0032479
name: regulation of type I interferon production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah]


id: GO:0032480
name: negative regulation of type I interferon production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah]


id: GO:0032481
name: positive regulation of type I interferon production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah]


id: GO:0032482
name: Rab protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state." [GOC:mah]


id: GO:0032483
name: regulation of Rab protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Rab protein signal transduction." [GOC:mah]


id: GO:0032484
name: Ral protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state." [GOC:mah]


id: GO:0032485
name: regulation of Ral protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Ral protein signal transduction." [GOC:mah]


id: GO:0032486
name: Rap protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state." [GOC:mah]


id: GO:0032487
name: regulation of Rap protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Rap protein signal transduction." [GOC:mah]


id: GO:0032488
name: Cdc42 protein signal transduction
namespace: biological_process
def:
  "A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state." [GOC:mah, PMID:18558478]


id: GO:0032489
name: regulation of Cdc42 protein signal transduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction." [GOC:mah]


id: GO:0032490
name: detection of molecule of bacterial origin
namespace: biological_process
def:
  "The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal." [GOC:add, GOC:rl]


id: GO:0032491
name: detection of molecule of fungal origin
namespace: biological_process
def:
  "The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal." [GOC:mah, GOC:rl]


id: GO:0032492
name: detection of molecule of oomycetes origin
namespace: biological_process
def:
  "The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal." [GOC:mah, GOC:rl]


id: GO:0032493
name: response to bacterial lipoprotein
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus." [GOC:add, PMID:12077222]


id: GO:0032494
name: response to peptidoglycan
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule." [GOC:add, ISBN:0721601464]


id: GO:0032495
name: response to muramyl dipeptide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan." [GOC:add]


id: GO:0032496
name: response to lipopolysaccharide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." [GOC:add, ISBN:0721601464]


id: GO:0032497
name: detection of lipopolysaccharide
namespace: biological_process
def:
  "The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." [GOC:add, PMID:15998797]


id: GO:0032498
name: detection of muramyl dipeptide
namespace: biological_process
def:
  "The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan." [GOC:rl, PMID:15998797]


id: GO:0032499
name: detection of peptidoglycan
namespace: biological_process
def:
  "The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule." [GOC:add, ISBN:0721601464]


id: GO:0032500
name: muramyl dipeptide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan." [GOC:rl]


id: GO:0032501
name: multicellular organismal process
namespace: biological_process
def:
  "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb]


id: GO:0032502
name: developmental process
namespace: biological_process
def:
  "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete]


id: GO:0032504
name: multicellular organism reproduction
namespace: biological_process
def:
  "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid]


id: GO:0032505
name: reproduction of a single-celled organism
namespace: biological_process
def:
  "The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete]


id: GO:0032506
name: cytokinetic process
namespace: biological_process
def:
  "A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells)." [GOC:bf, GOC:isa_complete, GOC:mah]


id: GO:0032507
name: maintenance of protein location in cell
namespace: biological_process
def:
  "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." [GOC:isa_complete, GOC:mah]


id: GO:0032508
name: DNA duplex unwinding
namespace: biological_process
def:
  "The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands." [GOC:isa_complete, GOC:mah]


id: GO:0032509
name: endosome transport via multivesicular body sorting pathway
namespace: biological_process
def:
  "The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment." [GOC:mah, PMID:12461556, PMID:16689637]


id: GO:0032510
name: endosome to lysosome transport via multivesicular body sorting pathway
namespace: biological_process
def:
  "The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome." [GOC:mah, PMID:12461556, PMID:16689637]


id: GO:0032511
name: late endosome to vacuole transport via multivesicular body sorting pathway
namespace: biological_process
def:
  "The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole." [GOC:mah, PMID:12461556, PMID:16689637]


id: GO:0032513
name: negative regulation of protein phosphatase type 2B activity
namespace: biological_process
def:
  "Any process that stops or reduces the activity of the enzyme protein phosphatase type 2B." [GOC:mah]


id: GO:0032514
name: positive regulation of protein phosphatase type 2B activity
namespace: biological_process
def:
  "Any process that activates or increases the activity of the enzyme protein phosphatase type 2B." [GOC:mah]


id: GO:0032517
name: SOD1-calcineurin complex
namespace: cellular_component
def:
  "A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1." [GOC:mah, PMID:17324120]


id: GO:0032518
name: amino acid-exporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(in) -> ADP + phosphate + amino acid(out)." [GOC:mah]


id: GO:0032519
name: cysteine-exporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(in) -> ADP + phosphate + cysteine(out)." [GOC:mah]


id: GO:0032520
name: amino acid-importing ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out) -> ADP + phosphate + amino acid(in)." [GOC:mah]


id: GO:0032521
name: D-methionine-exporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(in) -> ADP + phosphate + D-methionine(out)." [GOC:mah]


id: GO:0032522
name: D-methionine-importing ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out) -> ADP + phosphate + D-methionine(in)." [GOC:mah]


id: GO:0032523
name: silicon efflux transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of silicon from the inside of the cell to the outside of the cell across a membrane." [GOC:mah, PMID:17625566]


id: GO:0032525
name: somite rostral/caudal axis specification
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary." [GOC:bf, PMID:16326386, PMID:17360776]


id: GO:0032526
name: response to retinoic acid
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus." [GOC:sl]


id: GO:0032528
name: microvillus organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah]


id: GO:0032529
name: follicle cell microvillus organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments." [GOC:sart, PMID:16507588]


id: GO:0032530
name: regulation of microvillus organization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah]


id: GO:0032531
name: regulation of follicle cell microvillus organization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell." [GOC:mah]


id: GO:0032533
name: regulation of follicle cell microvillus length
namespace: biological_process
def:
  "A process that modulates the length of a microvillus on a follicle cell." [GOC:sart, PMID:16260500]


id: GO:0032537
name: host-seeking behavior
namespace: biological_process
def:
  "The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host." [GOC:mah, GOC:pr, PMID:11931033]


id: GO:0032538
name: regulation of host-seeking behavior
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah]


id: GO:0032539
name: negative regulation of host-seeking behavior
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah]


id: GO:0032540
name: positive regulation of host-seeking behavior
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah]


id: GO:0032541
name: cortical endoplasmic reticulum
namespace: cellular_component
def:
  "A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements." [GOC:se, PMID:10931860, PMID:17686782]


id: GO:0032542
name: sulfiredoxin activity
namespace: molecular_function
def:
  "Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R." [EC:1.8.98.2, PMID:16102934]


id: GO:0032543
name: mitochondrial translation
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." [GOC:go_curators]


id: GO:0032544
name: plastid translation
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." [GOC:go_curators]


id: GO:0032545
name: CURI complex
namespace: cellular_component
def:
  "A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p." [PMID:17452446]


id: GO:0032546
name: deoxyribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose." [GOC:mah]


id: GO:0032547
name: purine deoxyribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose." [GOC:mah]


id: GO:0032548
name: pyrimidine deoxyribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose." [GOC:mah]


id: GO:0032549
name: ribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah]


id: GO:0032550
name: purine ribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah]


id: GO:0032551
name: pyrimidine ribonucleoside binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose." [GOC:mah]


id: GO:0032552
name: deoxyribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah]


id: GO:0032553
name: ribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah]


id: GO:0032554
name: purine deoxyribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah]


id: GO:0032555
name: purine ribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah]


id: GO:0032556
name: pyrimidine deoxyribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah]


id: GO:0032557
name: pyrimidine ribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah]


id: GO:0032558
name: adenyl deoxyribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah]


id: GO:0032559
name: adenyl ribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah]


id: GO:0032560
name: guanyl deoxyribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah]


id: GO:0032561
name: guanyl ribonucleotide binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah]


id: GO:0032570
name: response to progesterone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus." [GOC:sl]


id: GO:0032571
name: response to vitamin K
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus." [GOC:sl]


id: GO:0032572
name: response to menaquinone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus." [GOC:sl]


id: GO:0032573
name: response to phylloquinone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus." [GOC:sl]


id: GO:0032575
name: ATP-dependent 5'-3' RNA helicase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'." [GOC:jp]


id: GO:0032576
name: O-linoleoyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule." [GOC:cb]


id: GO:0032577
name: phosphatidylcholine:cardiolipin O-linoleoyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule." [GOC:cb, GOC:mah]


id: GO:0032579
name: apical lamina of hyaline layer
namespace: cellular_component
def:
  "A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms." [GOC:ecd, PMID:2060714, PMID:7608987, PMID:9638331]


id: GO:0032580
name: Golgi cisterna membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex." [GOC:ecd, GOC:mah]


id: GO:0032581
name: ER-dependent peroxisome organization
namespace: biological_process
def:
  "A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum." [GOC:mah, PMID:16717127, PMID:17646399]


id: GO:0032588
name: trans-Golgi network membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network." [GOC:mah]


id: GO:0032592
name: integral component of mitochondrial membrane
namespace: cellular_component
def:
  "The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah]


id: GO:0032593
name: insulin-responsive compartment
namespace: cellular_component
def:
  "A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2." [PMID:17644329]


id: GO:0032596
name: protein transport into membrane raft
namespace: biological_process
def:
  "The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:mah]


id: GO:0032599
name: protein transport out of membrane raft
namespace: biological_process
def:
  "The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:mah]


id: GO:0032601
name: connective tissue growth factor production
namespace: biological_process
def:
  "The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032602
name: chemokine production
namespace: biological_process
def:
  "The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032603
name: fractalkine production
namespace: biological_process
def:
  "The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032604
name: granulocyte macrophage colony-stimulating factor production
namespace: biological_process
def:
  "The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032605
name: hepatocyte growth factor production
namespace: biological_process
def:
  "The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032606
name: type I interferon production
namespace: biological_process
def:
  "The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834]


id: GO:0032607
name: interferon-alpha production
namespace: biological_process
def:
  "The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032608
name: interferon-beta production
namespace: biological_process
def:
  "The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032609
name: interferon-gamma production
namespace: biological_process
def:
  "The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah]


id: GO:0032610
name: interleukin-1 alpha production
namespace: biological_process
def:
  "The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032611
name: interleukin-1 beta production
namespace: biological_process
def:
  "The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032612
name: interleukin-1 production
namespace: biological_process
def:
  "The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032613
name: interleukin-10 production
namespace: biological_process
def:
  "The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032614
name: interleukin-11 production
namespace: biological_process
def:
  "The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032615
name: interleukin-12 production
namespace: biological_process
def:
  "The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032616
name: interleukin-13 production
namespace: biological_process
def:
  "The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032617
name: interleukin-14 production
namespace: biological_process
def:
  "The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032618
name: interleukin-15 production
namespace: biological_process
def:
  "The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032619
name: interleukin-16 production
namespace: biological_process
def:
  "The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032620
name: interleukin-17 production
namespace: biological_process
def:
  "The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah, GOC:rv, PR:000001092, Wikipedia:Interleukin_17]


id: GO:0032621
name: interleukin-18 production
namespace: biological_process
def:
  "The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032622
name: interleukin-19 production
namespace: biological_process
def:
  "The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032623
name: interleukin-2 production
namespace: biological_process
def:
  "The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032624
name: interleukin-20 production
namespace: biological_process
def:
  "The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032625
name: interleukin-21 production
namespace: biological_process
def:
  "The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032626
name: interleukin-22 production
namespace: biological_process
def:
  "The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032627
name: interleukin-23 production
namespace: biological_process
def:
  "The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032628
name: interleukin-24 production
namespace: biological_process
def:
  "The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032629
name: interleukin-25 production
namespace: biological_process
def:
  "The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032630
name: interleukin-26 production
namespace: biological_process
def:
  "The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032631
name: interleukin-27 production
namespace: biological_process
def:
  "The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032632
name: interleukin-3 production
namespace: biological_process
def:
  "The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032633
name: interleukin-4 production
namespace: biological_process
def:
  "The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032634
name: interleukin-5 production
namespace: biological_process
def:
  "The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032635
name: interleukin-6 production
namespace: biological_process
def:
  "The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032636
name: interleukin-7 production
namespace: biological_process
def:
  "The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032637
name: interleukin-8 production
namespace: biological_process
def:
  "The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032638
name: interleukin-9 production
namespace: biological_process
def:
  "The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032639
name: TRAIL production
namespace: biological_process
def:
  "The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032640
name: tumor necrosis factor production
namespace: biological_process
def:
  "The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032641
name: lymphotoxin A production
namespace: biological_process
def:
  "The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032643
name: regulation of connective tissue growth factor production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah]


id: GO:0032645
name: regulation of granulocyte macrophage colony-stimulating factor production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah]


id: GO:0032646
name: regulation of hepatocyte growth factor production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah]


id: GO:0032647
name: regulation of interferon-alpha production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interferon-alpha production." [GOC:mah]


id: GO:0032648
name: regulation of interferon-beta production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interferon-beta production." [GOC:mah]


id: GO:0032649
name: regulation of interferon-gamma production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah]


id: GO:0032650
name: regulation of interleukin-1 alpha production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah]


id: GO:0032651
name: regulation of interleukin-1 beta production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah]


id: GO:0032660
name: regulation of interleukin-17 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah]


id: GO:0032680
name: regulation of tumor necrosis factor production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah]


id: GO:0032682
name: negative regulation of chemokine production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production." [GOC:mah]


id: GO:0032683
name: negative regulation of connective tissue growth factor production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah]


id: GO:0032684
name: negative regulation of fractalkine production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production." [GOC:mah]


id: GO:0032685
name: negative regulation of granulocyte macrophage colony-stimulating factor production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah]


id: GO:0032686
name: negative regulation of hepatocyte growth factor production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah]


id: GO:0032687
name: negative regulation of interferon-alpha production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production." [GOC:mah]


id: GO:0032688
name: negative regulation of interferon-beta production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production." [GOC:mah]


id: GO:0032689
name: negative regulation of interferon-gamma production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah]


id: GO:0032690
name: negative regulation of interleukin-1 alpha production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah]


id: GO:0032691
name: negative regulation of interleukin-1 beta production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah]


id: GO:0032692
name: negative regulation of interleukin-1 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production." [GOC:mah]


id: GO:0032693
name: negative regulation of interleukin-10 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production." [GOC:mah]


id: GO:0032694
name: negative regulation of interleukin-11 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production." [GOC:mah]


id: GO:0032695
name: negative regulation of interleukin-12 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production." [GOC:mah]


id: GO:0032696
name: negative regulation of interleukin-13 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production." [GOC:mah]


id: GO:0032697
name: negative regulation of interleukin-14 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production." [GOC:mah]


id: GO:0032698
name: negative regulation of interleukin-15 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production." [GOC:mah]


id: GO:0032699
name: negative regulation of interleukin-16 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production." [GOC:mah]


id: GO:0032700
name: negative regulation of interleukin-17 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah]


id: GO:0032701
name: negative regulation of interleukin-18 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production." [GOC:mah]


id: GO:0032702
name: negative regulation of interleukin-19 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production." [GOC:mah]


id: GO:0032703
name: negative regulation of interleukin-2 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production." [GOC:mah]


id: GO:0032704
name: negative regulation of interleukin-20 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production." [GOC:mah]


id: GO:0032705
name: negative regulation of interleukin-21 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production." [GOC:mah]


id: GO:0032706
name: negative regulation of interleukin-22 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production." [GOC:mah]


id: GO:0032707
name: negative regulation of interleukin-23 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production." [GOC:mah]


id: GO:0032708
name: negative regulation of interleukin-24 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production." [GOC:mah]


id: GO:0032709
name: negative regulation of interleukin-25 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production." [GOC:mah]


id: GO:0032710
name: negative regulation of interleukin-26 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production." [GOC:mah]


id: GO:0032711
name: negative regulation of interleukin-27 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production." [GOC:mah]


id: GO:0032712
name: negative regulation of interleukin-3 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production." [GOC:mah]


id: GO:0032713
name: negative regulation of interleukin-4 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production." [GOC:mah]


id: GO:0032714
name: negative regulation of interleukin-5 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production." [GOC:mah]


id: GO:0032715
name: negative regulation of interleukin-6 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production." [GOC:mah]


id: GO:0032716
name: negative regulation of interleukin-7 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production." [GOC:mah]


id: GO:0032717
name: negative regulation of interleukin-8 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production." [GOC:mah]


id: GO:0032718
name: negative regulation of interleukin-9 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production." [GOC:mah]


id: GO:0032719
name: negative regulation of TRAIL production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production." [GOC:mah]


id: GO:0032720
name: negative regulation of tumor necrosis factor production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah]


id: GO:0032721
name: negative regulation of lymphotoxin A production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production." [GOC:mah]


id: GO:0032722
name: positive regulation of chemokine production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of chemokine production." [GOC:mah]


id: GO:0032723
name: positive regulation of connective tissue growth factor production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah]


id: GO:0032724
name: positive regulation of fractalkine production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of fractalkine production." [GOC:mah]


id: GO:0032725
name: positive regulation of granulocyte macrophage colony-stimulating factor production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah]


id: GO:0032726
name: positive regulation of hepatocyte growth factor production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah]


id: GO:0032727
name: positive regulation of interferon-alpha production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interferon-alpha production." [GOC:mah]


id: GO:0032728
name: positive regulation of interferon-beta production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interferon-beta production." [GOC:mah]


id: GO:0032729
name: positive regulation of interferon-gamma production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah]


id: GO:0032730
name: positive regulation of interleukin-1 alpha production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah]


id: GO:0032731
name: positive regulation of interleukin-1 beta production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah]


id: GO:0032732
name: positive regulation of interleukin-1 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-1 production." [GOC:mah]


id: GO:0032733
name: positive regulation of interleukin-10 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-10 production." [GOC:mah]


id: GO:0032734
name: positive regulation of interleukin-11 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-11 production." [GOC:mah]


id: GO:0032735
name: positive regulation of interleukin-12 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-12 production." [GOC:mah]


id: GO:0032736
name: positive regulation of interleukin-13 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-13 production." [GOC:mah]


id: GO:0032737
name: positive regulation of interleukin-14 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-14 production." [GOC:mah]


id: GO:0032738
name: positive regulation of interleukin-15 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-15 production." [GOC:mah]


id: GO:0032739
name: positive regulation of interleukin-16 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-16 production." [GOC:mah]


id: GO:0032740
name: positive regulation of interleukin-17 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah]


id: GO:0032741
name: positive regulation of interleukin-18 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-18 production." [GOC:mah]


id: GO:0032742
name: positive regulation of interleukin-19 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-19 production." [GOC:mah]


id: GO:0032743
name: positive regulation of interleukin-2 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-2 production." [GOC:mah]


id: GO:0032744
name: positive regulation of interleukin-20 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-20 production." [GOC:mah]


id: GO:0032745
name: positive regulation of interleukin-21 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-21 production." [GOC:mah]


id: GO:0032746
name: positive regulation of interleukin-22 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-22 production." [GOC:mah]


id: GO:0032747
name: positive regulation of interleukin-23 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-23 production." [GOC:mah]


id: GO:0032748
name: positive regulation of interleukin-24 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-24 production." [GOC:mah]


id: GO:0032749
name: positive regulation of interleukin-25 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-25 production." [GOC:mah]


id: GO:0032750
name: positive regulation of interleukin-26 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-26 production." [GOC:mah]


id: GO:0032751
name: positive regulation of interleukin-27 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-27 production." [GOC:mah]


id: GO:0032752
name: positive regulation of interleukin-3 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-3 production." [GOC:mah]


id: GO:0032753
name: positive regulation of interleukin-4 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-4 production." [GOC:mah]


id: GO:0032754
name: positive regulation of interleukin-5 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-5 production." [GOC:mah]


id: GO:0032755
name: positive regulation of interleukin-6 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-6 production." [GOC:mah]


id: GO:0032756
name: positive regulation of interleukin-7 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-7 production." [GOC:mah]


id: GO:0032757
name: positive regulation of interleukin-8 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-8 production." [GOC:mah]


id: GO:0032758
name: positive regulation of interleukin-9 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of interleukin-9 production." [GOC:mah]


id: GO:0032759
name: positive regulation of TRAIL production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of TRAIL production." [GOC:mah]


id: GO:0032760
name: positive regulation of tumor necrosis factor production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah]


id: GO:0032761
name: positive regulation of lymphotoxin A production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production." [GOC:mah]


id: GO:0032763
name: regulation of mast cell cytokine production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of mast cell cytokine production." [GOC:mah]


id: GO:0032764
name: negative regulation of mast cell cytokine production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production." [GOC:mah]


id: GO:0032765
name: positive regulation of mast cell cytokine production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production." [GOC:mah]


id: GO:0032766
name: NHE3/E3KARP/ACTN4 complex
namespace: cellular_component
def:
  "A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments." [PMID:11948184]


id: GO:0032767
name: copper-dependent protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper." [GOC:ecd, PMID:16884690]


id: GO:0032771
name: regulation of monophenol monooxygenase activity
namespace: biological_process
def:
  "Any process that modulates the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb, PMID:2494997]


id: GO:0032772
name: negative regulation of monophenol monooxygenase activity
namespace: biological_process
def:
  "Any process that stops or reduces the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032773
name: positive regulation of monophenol monooxygenase activity
namespace: biological_process
def:
  "Any process that activates or increases the activity of the enzyme monophenol oxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb, PMID:2494997]


id: GO:0032774
name: RNA biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH]


id: GO:0032777
name: Piccolo NuA4 histone acetyltransferase complex
namespace: cellular_component
def:
  "A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p." [GOC:rb, PMID:12782659, PMID:15964809]


id: GO:0032778
name: cobalt-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in)." [GOC:mlg, GOC:mtg_transport, ISBN:0815340729]


id: GO:0032782
name: bile acid secretion
namespace: biological_process
def:
  "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd]


id: GO:0032783
name: ELL-EAF complex
namespace: cellular_component
def:
  "A heterodimeric protein complex that acts as an RNA polymerase II elongation factor; the complex is conserved from yeast to humans, and is present in S. pombe, but absent from S. cerevisiae." [PMID:17150956]


id: GO:0032784
name: regulation of DNA-templated transcription, elongation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH]


id: GO:0032785
name: negative regulation of DNA-templated transcription, elongation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH]


id: GO:0032786
name: positive regulation of DNA-templated transcription, elongation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH]


id: GO:0032787
name: monocarboxylic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk]


id: GO:0032788
name: saturated monocarboxylic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds." [GOC:mah, GOC:vk]


id: GO:0032789
name: unsaturated monocarboxylic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds." [GOC:mah, GOC:vk]


id: GO:0032790
name: ribosome disassembly
namespace: biological_process
def:
  "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk]


id: GO:0032792
name: negative regulation of CREB transcription factor activity
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]


id: GO:0032793
name: positive regulation of CREB transcription factor activity
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb]


id: GO:0032796
name: uropod organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated." [GOC:add, ISBN:0781735149, PMID:12714569, PMID:12787750]


id: GO:0032797
name: SMN complex
namespace: cellular_component
def:
  "A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus." [PMID:16434402, PMID:17023415]


id: GO:0032798
name: Swi5-Sfr1 complex
namespace: cellular_component
def:
  "A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces)." [PMID:15620352, PMID:16921379]


id: GO:0032800
name: receptor biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah]


id: GO:0032801
name: receptor catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah]


id: GO:0032802
name: low-density lipoprotein particle receptor catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah]


id: GO:0032803
name: regulation of low-density lipoprotein particle receptor catabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors." [GOC:mah]


id: GO:0032804
name: negative regulation of low-density lipoprotein particle receptor catabolic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors." [GOC:mah]


id: GO:0032805
name: positive regulation of low-density lipoprotein particle receptor catabolic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors." [GOC:mah]


id: GO:0032806
name: carboxy-terminal domain protein kinase complex
namespace: cellular_component
def:
  "A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5." [PMID:15047695, PMID:16721054, PMID:17079683]


id: GO:0032807
name: DNA ligase IV complex
namespace: cellular_component
def:
  "A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p." [PMID:16314503]


id: GO:0032808
name: lacrimal gland development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye." [GOC:ln]


id: GO:0032809
name: neuronal cell body membrane
namespace: cellular_component
def:
  "The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites." [GOC:jl]


id: GO:0032810
name: sterol response element binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism." [GOC:vk, PMID:11994399]


id: GO:0032811
name: negative regulation of epinephrine secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk]


id: GO:0032812
name: positive regulation of epinephrine secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk]


id: GO:0032813
name: tumor necrosis factor receptor superfamily binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily." [GOC:add]


id: GO:0032814
name: regulation of natural killer cell activation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of natural killer cell activation." [GOC:mah]


id: GO:0032815
name: negative regulation of natural killer cell activation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation." [GOC:mah]


id: GO:0032816
name: positive regulation of natural killer cell activation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell activation." [GOC:mah]


id: GO:0032817
name: regulation of natural killer cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of natural killer cell proliferation." [GOC:mah]


id: GO:0032818
name: negative regulation of natural killer cell proliferation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation." [GOC:mah]


id: GO:0032819
name: positive regulation of natural killer cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation." [GOC:mah]


id: GO:0032820
name: regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]


id: GO:0032821
name: negative regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]


id: GO:0032822
name: positive regulation of natural killer cell proliferation involved in immune response
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah]


id: GO:0032823
name: regulation of natural killer cell differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of natural killer cell differentiation." [GOC:mah]


id: GO:0032824
name: negative regulation of natural killer cell differentiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation." [GOC:mah]


id: GO:0032825
name: positive regulation of natural killer cell differentiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation." [GOC:mah]


id: GO:0032826
name: regulation of natural killer cell differentiation involved in immune response
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah]


id: GO:0032827
name: negative regulation of natural killer cell differentiation involved in immune response
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah]


id: GO:0032828
name: positive regulation of natural killer cell differentiation involved in immune response
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah]


id: GO:0032829
name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah]


id: GO:0032830
name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah]


id: GO:0032831
name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah]


id: GO:0032832
namespace: biological_process
name:
  regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

def:
  "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah]


id: GO:0032833
namespace: biological_process
name:
  negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah]


id: GO:0032834
namespace: biological_process
name:
  positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

def:
  "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah]


id: GO:0032835
name: glomerulus development
namespace: biological_process
def:
  "The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment." [GOC:mah, GOC:mtg_kidney_jan10]


id: GO:0032836
name: glomerular basement membrane development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration." [GOC:sr]


id: GO:0032837
name: distributive segregation
namespace: biological_process
def:
  "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a \"backup\" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally." [GOC:expert_rsh, GOC:ma, GOC:sart]


id: GO:0032838
name: cell projection cytoplasm
namespace: cellular_component
def:
  "All of the contents of a cell projection, excluding the plasma membrane surrounding the projection." [GOC:mah]


id: GO:0032840
name: intramolecular proline-rich ligand binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a proline-rich region within the same polypeptide." [GOC:pf]


id: GO:0032841
name: calcitonin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid." [GOC:ecd]


id: GO:0032843
name: hydroperoxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol." [GOC:mlg, PMID:12540833]


id: GO:0032845
name: negative regulation of homeostatic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process." [GOC:mah]


id: GO:0032846
name: positive regulation of homeostatic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of a homeostatic process." [GOC:mah]


id: GO:0032847
name: regulation of cellular pH reduction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah]


id: GO:0032848
name: negative regulation of cellular pH reduction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah]


id: GO:0032849
name: positive regulation of cellular pH reduction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah]


id: GO:0032865
name: ERMES complex
namespace: cellular_component
def:
  "A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth." [GOC:mcc, PMID:19556461]


id: GO:0032866
name: D-xylose:NADP reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+." [PMID:12724380, PMID:15184173]


id: GO:0032867
name: L-arabinose:NADP reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+." [PMID:12724380, PMID:15184173]


id: GO:0032868
name: response to insulin
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732]


id: GO:0032869
name: cellular response to insulin stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732]


id: GO:0032870
name: cellular response to hormone stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:mah]


id: GO:0032871
name: regulation of karyogamy
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah]


id: GO:0032872
name: regulation of stress-activated MAPK cascade
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah]


id: GO:0032873
name: negative regulation of stress-activated MAPK cascade
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah]


id: GO:0032874
name: positive regulation of stress-activated MAPK cascade
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah]


id: GO:0032876
name: negative regulation of DNA endoreduplication
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." [GOC:mah]


id: GO:0032877
name: positive regulation of DNA endoreduplication
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." [GOC:mah]


id: GO:0032878
name: regulation of establishment or maintenance of cell polarity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah]


id: GO:0032879
name: regulation of localization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah]


id: GO:0032880
name: regulation of protein localization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb]


id: GO:0032881
name: regulation of polysaccharide metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah]


id: GO:0032882
name: regulation of chitin metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah]


id: GO:0032883
name: regulation of chitin biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah]


id: GO:0032884
name: regulation of cell wall chitin biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin." [GOC:mah]


id: GO:0032885
name: regulation of polysaccharide biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah]


id: GO:0032886
name: regulation of microtubule-based process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah]


id: GO:0032887
name: regulation of spindle elongation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle." [GOC:mah]


id: GO:0032888
name: regulation of mitotic spindle elongation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle." [GOC:mah]


id: GO:0032889
name: regulation of vacuole fusion, non-autophagic
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:mah]


id: GO:0032890
name: regulation of organic acid transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032891
name: negative regulation of organic acid transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032892
name: positive regulation of organic acid transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032893
name: regulation of gluconate transport
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032894
name: negative regulation of gluconate transport
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032895
name: positive regulation of gluconate transport
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]


id: GO:0032896
name: palmitoyl-CoA 9-desaturase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O." [GOC:kmv]


id: GO:0032897
name: negative regulation of viral transcription
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription." [GOC:mah]


id: GO:0032898
name: neurotrophin production
namespace: biological_process
def:
  "The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth." [GOC:ecd, GOC:mah, GOC:mtg_MIT_16mar07]


id: GO:0032899
name: regulation of neurotrophin production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of a neurotrophin." [GOC:mah]


id: GO:0032900
name: negative regulation of neurotrophin production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin." [GOC:mah]


id: GO:0032901
name: positive regulation of neurotrophin production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin." [GOC:mah]


id: GO:0032902
name: nerve growth factor production
namespace: biological_process
def:
  "The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels." [GOC:ecd, GOC:mah]


id: GO:0032903
name: regulation of nerve growth factor production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF)." [GOC:mah]


id: GO:0032904
name: negative regulation of nerve growth factor production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF)." [GOC:mah]


id: GO:0032905
name: transforming growth factor beta1 production
namespace: biological_process
def:
  "The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032906
name: transforming growth factor beta2 production
namespace: biological_process
def:
  "The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032907
name: transforming growth factor beta3 production
namespace: biological_process
def:
  "The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah]


id: GO:0032908
name: regulation of transforming growth factor beta1 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah]


id: GO:0032909
name: regulation of transforming growth factor beta2 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah]


id: GO:0032910
name: regulation of transforming growth factor beta3 production
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah]


id: GO:0032911
name: negative regulation of transforming growth factor beta1 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah]


id: GO:0032912
name: negative regulation of transforming growth factor beta2 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah]


id: GO:0032913
name: negative regulation of transforming growth factor beta3 production
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah]


id: GO:0032914
name: positive regulation of transforming growth factor beta1 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah]


id: GO:0032915
name: positive regulation of transforming growth factor beta2 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah]


id: GO:0032916
name: positive regulation of transforming growth factor beta3 production
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah]


id: GO:0032921
name: sarcosine oxidase complex
namespace: cellular_component
def:
  "A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity." [GOC:mah, GOC:mlg]


id: GO:0032922
name: circadian regulation of gene expression
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours." [GOC:mah]


id: GO:0032923
name: organic phosphonate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included." [GOC:js]


id: GO:0032924
name: activin receptor signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:rl, GOC:signaling]


id: GO:0032925
name: regulation of activin receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl]


id: GO:0032926
name: negative regulation of activin receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl]


id: GO:0032927
name: positive regulation of activin receptor signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl]


id: GO:0032928
name: regulation of superoxide anion generation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah]


id: GO:0032929
name: negative regulation of superoxide anion generation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah]


id: GO:0032930
name: positive regulation of superoxide anion generation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah]


id: GO:0032931
name: histone acetyltransferase activity (H3-K56 specific)
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56)." [EC:2.3.1.48]


id: GO:0032932
name: negative regulation of astral microtubule depolymerization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules." [GOC:mah]


id: GO:0032933
name: SREBP signaling pathway
namespace: biological_process
def:
  "A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription." [GOC:bf, GOC:mah, GOC:signaling, GOC:vw, PMID:12923525, PMID:22017871]


id: GO:0032934
name: sterol binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [CHEBI:15889, GOC:mah]


id: GO:0032935
name: sterol sensor activity
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol." [GOC:mah]


id: GO:0032936
name: SREBP-SCAP complex
namespace: cellular_component
def:
  "A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed." [PMID:12923525]


id: GO:0032937
name: SREBP-SCAP-Insig complex
namespace: cellular_component
def:
  "A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane." [PMID:12923525]


id: GO:0032938
name: negative regulation of translation in response to oxidative stress
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah]


id: GO:0032939
name: positive regulation of translation in response to oxidative stress
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah]


