# go

id: GO:0060888
name: limb epidermis stratification
namespace: biological_process
def:
  "The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060889
name: limb basal epidermal cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060890
name: limb spinous cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060891
name: limb granular cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060892
name: limb basal epidermal cell fate specification
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060893
name: limb granular cell fate specification
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060894
name: limb spinous cell fate specification
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060895
name: retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060896
name: neural plate pattern specification
namespace: biological_process
def:
  "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060897
name: neural plate regionalization
namespace: biological_process
def:
  "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060898
name: eye field cell fate commitment involved in camera-type eye formation
namespace: biological_process
def:
  "The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060899
name: regulation of transcription involved in eye field cell fate commitment of camera-type eye
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060900
name: embryonic camera-type eye formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060901
name: regulation of hair cycle by canonical Wnt signaling pathway
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060902
name: regulation of hair cycle by BMP signaling pathway
namespace: biological_process
def:
  "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060903
name: positive regulation of meiosis I
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [GOC:dph, GOC:tb]


id: GO:0060904
name: regulation of protein folding in endoplasmic reticulum
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)." [GOC:dph, GOC:tb]


id: GO:0060905
name: regulation of induction of conjugation upon nitrogen starvation
namespace: biological_process
def:
  "Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation." [GOC:dph, GOC:tb]


id: GO:0060906
name: negative regulation of chromatin silencing by small RNA
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region." [GOC:dph, GOC:tb]


id: GO:0060907
name: positive regulation of macrophage cytokine production
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:dph, GOC:tb]


id: GO:0060909
name: regulation of DNA replication initiation involved in plasmid copy number maintenance
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb]


id: GO:0060910
name: negative regulation of DNA replication initiation involved in plasmid copy number maintenance
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb]


id: GO:0060911
name: cardiac cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system." [GOC:mtg_heart]


id: GO:0060912
name: cardiac cell fate specification
namespace: biological_process
def:
  "The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:mtg_heart]


id: GO:0060913
name: cardiac cell fate determination
namespace: biological_process
def:
  "The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:mtg_heart]


id: GO:0060914
name: heart formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart]


id: GO:0060915
name: mesenchymal cell differentiation involved in lung development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph]


id: GO:0060916
name: mesenchymal cell proliferation involved in lung development
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph]


id: GO:0060917
name: regulation of (1->6)-beta-D-glucan biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans." [GOC:dph, GOC:tb]


id: GO:0060918
name: auxin transport
namespace: biological_process
def:
  "The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]


id: GO:0060920
name: cardiac pacemaker cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]


id: GO:0060921
name: sinoatrial node cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart]


id: GO:0060922
name: atrioventricular node cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart]


id: GO:0060923
name: cardiac muscle cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart]


id: GO:0060924
name: atrial cardiac muscle cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart]


id: GO:0060925
name: ventricular cardiac muscle cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart]


id: GO:0060926
name: cardiac pacemaker cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]


id: GO:0060927
name: cardiac pacemaker cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]


id: GO:0060928
name: atrioventricular node cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart]


id: GO:0060929
name: atrioventricular node cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells." [GOC:mtg_heart]


id: GO:0060930
name: sinoatrial node cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart]


id: GO:0060931
name: sinoatrial node cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart]


id: GO:0060932
name: His-Purkinje system cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]


id: GO:0060933
name: His-Purkinje system cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]


id: GO:0060934
name: His-Purkinje system cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]


id: GO:0060935
name: cardiac fibroblast cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060936
name: cardiac fibroblast cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060937
name: cardiac fibroblast cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060938
name: epicardium-derived cardiac fibroblast cell differentiation
namespace: biological_process
def:
  "The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060939
name: epicardium-derived cardiac fibroblast cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060940
name: epithelial to mesenchymal transition involved in cardiac fibroblast development
namespace: biological_process
def:
  "A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast." [GOC:mtg_heart]


id: GO:0060941
name: epicardium-derived cardiac fibroblast cell fate commitment
namespace: biological_process
def:
  "The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060942
name: neural crest-derived cardiac fibroblast cell differentiation
namespace: biological_process
def:
  "The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060943
name: neural crest-derived cardiac fibroblast cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060944
name: neural crest-derived cardiac fibroblast cell fate commitment
namespace: biological_process
def:
  "The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]


id: GO:0060945
name: cardiac neuron differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart]


id: GO:0060946
name: cardiac blood vessel endothelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart]


id: GO:0060947
name: cardiac vascular smooth muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers." [GOC:mtg_heart]


id: GO:0060948
name: cardiac vascular smooth muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state." [GOC:mtg_heart]


id: GO:0060949
name: cardiac vascular smooth muscle cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell." [GOC:mtg_heart]


id: GO:0060950
name: cardiac glial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart]


id: GO:0060951
name: neural crest-derived cardiac glial cell differentiation
namespace: biological_process
def:
  "The process in which a neural crest cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart]


id: GO:0060952
name: cardiac glial cell development
namespace: biological_process
def:
  "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart]


id: GO:0060953
name: cardiac glial cell fate commitment
namespace: biological_process
def:
  "The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells." [GOC:mtg_heart]


id: GO:0060954
name: neural crest-derived cardiac glial cell development
namespace: biological_process
def:
  "The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:mtg_heart]


id: GO:0060955
name: neural crest-derived cardiac glial cell fate commitment
namespace: biological_process
def:
  "The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells." [GOC:mtg_heart]


id: GO:0060956
name: endocardial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart]


id: GO:0060957
name: endocardial cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart]


id: GO:0060958
name: endocardial cell development
namespace: biological_process
def:
  "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart]


id: GO:0060959
name: cardiac neuron development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart]


id: GO:0060960
name: cardiac neuron fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart." [GOC:mtg_heart]


id: GO:0060961
name: phospholipase D inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate." [GOC:dph, GOC:tb]


id: GO:0060962
name: regulation of ribosomal protein gene transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060963
name: positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060964
name: regulation of gene silencing by miRNA
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression." [GOC:dph, GOC:tb]


id: GO:0060965
name: negative regulation of gene silencing by miRNA
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression." [GOC:dph, GOC:tb]


id: GO:0060966
name: regulation of gene silencing by RNA
namespace: biological_process
def:
  "Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:tb]


id: GO:0060967
name: negative regulation of gene silencing by RNA
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:tb]


id: GO:0060968
name: regulation of gene silencing
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation." [GOC:dph, GOC:tb]


id: GO:0060969
name: negative regulation of gene silencing
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation." [GOC:dph, GOC:tb]


id: GO:0060970
name: embryonic heart tube dorsal/ventral pattern formation
namespace: biological_process
def:
  "The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis." [GOC:mtg_heart]


id: GO:0060971
name: embryonic heart tube left/right pattern formation
namespace: biological_process
def:
  "The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place." [GOC:mtg_heart]


id: GO:0060972
name: left/right pattern formation
namespace: biological_process
def:
  "The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:mtg_heart]


id: GO:0060973
name: cell migration involved in heart development
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart]


id: GO:0060974
name: cell migration involved in heart formation
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart]


id: GO:0060975
name: cardioblast migration to the midline involved in heart field formation
namespace: biological_process
def:
  "The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart]


id: GO:0060976
name: coronary vasculature development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart]


id: GO:0060977
name: coronary vasculature morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart]


id: GO:0060978
name: angiogenesis involved in coronary vascular morphogenesis
namespace: biological_process
def:
  "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart]


id: GO:0060979
name: vasculogenesis involved in coronary vascular morphogenesis
namespace: biological_process
def:
  "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart]


id: GO:0060980
name: cell migration involved in coronary vasculogenesis
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart]


id: GO:0060981
name: cell migration involved in coronary angiogenesis
namespace: biological_process
def:
  "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart]


id: GO:0060982
name: coronary artery morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle." [GOC:mtg_heart]


id: GO:0060983
name: epicardium-derived cardiac vascular smooth muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers." [GOC:mtg_heart]


id: GO:0060984
name: epicardium-derived cardiac vascular smooth muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state." [GOC:mtg_heart]


id: GO:0060985
name: epicardium-derived cardiac vascular smooth muscle cell fate commitment
namespace: biological_process
def:
  "The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell." [GOC:mtg_heart]


id: GO:0060987
name: lipid tube
namespace: cellular_component
def:
  "A macromolecular complex that contains a tube of lipid surrounded by a protein coat." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060988
name: lipid tube assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as the fuse or undergo fission." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060989
name: lipid tube assembly involved in organelle fusion
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060990
name: lipid tube assembly involved in organelle fission
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060991
name: obsolete lipid tube assembly involved in cytokinesis
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060992
name: response to fungicide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi." [GOC:dph]


id: GO:0060993
name: kidney morphogenesis
namespace: biological_process
def:
  "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0060994
name: regulation of transcription from RNA polymerase II promoter involved in kidney development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0060995
name: cell-cell signaling involved in kidney development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0060996
name: dendritic spine development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph]


id: GO:0060997
name: dendritic spine morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph]


id: GO:0060998
name: regulation of dendritic spine development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph]


id: GO:0060999
name: positive regulation of dendritic spine development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061000
name: negative regulation of dendritic spine development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061001
name: regulation of dendritic spine morphogenesis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph]


id: GO:0061002
name: negative regulation of dendritic spine morphogenesis
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph]


id: GO:0061004
name: pattern specification involved in kidney development
namespace: biological_process
def:
  "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061005
name: cell differentiation involved in kidney development
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061006
name: regulation of cell proliferation involved in kidney morphogenesis
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061007
name: hepaticobiliary system process
namespace: biological_process
def:
  "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]


id: GO:0061008
name: hepaticobiliary system development
namespace: biological_process
def:
  "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]


id: GO:0061009
name: common bile duct development
namespace: biological_process
def:
  "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine." [PMID:20614624]


id: GO:0061010
name: gall bladder development
namespace: biological_process
def:
  "The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile." [GOC:dph]


id: GO:0061011
name: hepatic duct development
namespace: biological_process
def:
  "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624]


id: GO:0061013
name: regulation of mRNA catabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0061014
name: positive regulation of mRNA catabolic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0061015
name: snRNA import into nucleus
namespace: biological_process
def:
  "The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0061016
name: snRNA import into Cajal body
namespace: biological_process
def:
  "The directed movement of snRNA, small nuclear ribonucleic acid, into a Cajal body." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0061017
name: hepatoblast differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394]


id: GO:0061024
name: membrane organization
namespace: biological_process
def:
  "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb]


id: GO:0061025
name: membrane fusion
namespace: biological_process
def:
  "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb]


id: GO:0061026
name: cardiac muscle tissue regeneration
namespace: biological_process
def:
  "The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage." [GOC:dph]


id: GO:0061027
name: umbilical cord development
namespace: biological_process
def:
  "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph]


id: GO:0061028
name: establishment of endothelial barrier
namespace: biological_process
def:
  "The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition." [GOC:dph]


id: GO:0061029
name: eyelid development in camera-type eye
namespace: biological_process
def:
  "The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye." [GOC:dph, GOC:yaf]


id: GO:0061030
name: epithelial cell differentiation involved in mammary gland alveolus development
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus." [GOC:dph, GOC:yaf]


id: GO:0061031
name: endodermal digestive tract morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm." [GOC:dph, GOC:yaf]


id: GO:0061032
name: visceral serous pericardium development
namespace: biological_process
def:
  "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf]


id: GO:0061033
name: secretion by lung epithelial cell involved in lung growth
namespace: biological_process
def:
  "The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development." [GOC:dph]


id: GO:0061034
name: olfactory bulb mitral cell layer development
namespace: biological_process
def:
  "The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer." [GOC:dph]


id: GO:0061035
name: regulation of cartilage development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]


id: GO:0061036
name: positive regulation of cartilage development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]


id: GO:0061037
name: negative regulation of cartilage development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]


id: GO:0061038
name: uterus morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph]


id: GO:0061041
name: regulation of wound healing
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:BHF, GOC:dph]


id: GO:0061042
name: vascular wound healing
namespace: biological_process
def:
  "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:BHF, GOC:dph]


id: GO:0061043
name: regulation of vascular wound healing
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:dph]


id: GO:0061044
name: negative regulation of vascular wound healing
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:BHF, GOC:dph]


id: GO:0061045
name: negative regulation of wound healing
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:dph]


id: GO:0061046
name: regulation of branching involved in lung morphogenesis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf]


id: GO:0061048
name: negative regulation of branching involved in lung morphogenesis
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf]


id: GO:0061049
name: cell growth involved in cardiac muscle cell development
namespace: biological_process
def:
  "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]


id: GO:0061050
name: regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]


id: GO:0061051
name: positive regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]


id: GO:0061052
name: negative regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]


id: GO:0061053
name: somite development
namespace: biological_process
def:
  "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph]


id: GO:0061054
name: dermatome development
namespace: biological_process
def:
  "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph]


id: GO:0061055
name: myotome development
namespace: biological_process
def:
  "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph]


id: GO:0061056
name: sclerotome development
namespace: biological_process
def:
  "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph]


id: GO:0061057
name: peptidoglycan recognition protein signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides." [GOC:dph, PMID:18688280]


id: GO:0061058
name: regulation of peptidoglycan recognition protein signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph]


id: GO:0061059
name: positive regulation of peptidoglycan recognition protein signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph]


id: GO:0061060
name: negative regulation of peptidoglycan recognition protein signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph]


id: GO:0061061
name: muscle structure development
namespace: biological_process
def:
  "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph]


id: GO:0061062
name: regulation of nematode larval development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]


id: GO:0061063
name: positive regulation of nematode larval development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]


id: GO:0061064
name: negative regulation of nematode larval development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]


id: GO:0061065
name: regulation of dauer larval development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv]


id: GO:0061066
name: positive regulation of dauer larval development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv]


id: GO:0061067
name: negative regulation of dauer larval development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv]


id: GO:0061068
name: urethra development
namespace: biological_process
def:
  "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph]


id: GO:0061069
name: male urethra development
namespace: biological_process
def:
  "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph]


id: GO:0061070
name: female urethra development
namespace: biological_process
def:
  "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph]


id: GO:0061071
name: urethra epithelium development
namespace: biological_process
def:
  "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph]


id: GO:0061072
name: iris morphogenesis
namespace: biological_process
def:
  "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph]


id: GO:0061073
name: ciliary body morphogenesis
namespace: biological_process
def:
  "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph]


id: GO:0061074
name: regulation of neural retina development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]


id: GO:0061075
name: positive regulation of neural retina development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]


id: GO:0061076
name: negative regulation of neural retina development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]


id: GO:0061077
name: chaperone-mediated protein folding
namespace: biological_process
def:
  "The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone." [GOC:dph, GOC:vw]


id: GO:0061078
name: positive regulation of prostaglandin secretion involved in immune response
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response." [GOC:BHF, GOC:dph]


id: GO:0061079
name: left horn of sinus venosus development
namespace: biological_process
def:
  "The progression of the left horn of the sinus venosus from its initial formation to the mature structure." [GOC:dph]


id: GO:0061080
name: right horn of sinus venosus development
namespace: biological_process
def:
  "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph]


id: GO:0061081
name: positive regulation of myeloid leukocyte cytokine production involved in immune response
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response." [GOC:BHF, GOC:dph]


id: GO:0061083
name: regulation of protein refolding
namespace: biological_process
def:
  "Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones." [GOC:dph, GOC:tb]


id: GO:0061084
name: negative regulation of protein refolding
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0061085
name: regulation of histone H3-K27 methylation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb]


id: GO:0061086
name: negative regulation of histone H3-K27 methylation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb]


id: GO:0061087
name: positive regulation of histone H3-K27 methylation
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb]


id: GO:0061088
name: regulation of sequestering of zinc ion
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0061089
name: negative regulation of sequestering of zinc ion
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0061090
name: positive regulation of sequestering of zinc ion
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0061091
name: regulation of phospholipid translocation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


id: GO:0061092
name: positive regulation of phospholipid translocation
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


id: GO:0061093
name: negative regulation of phospholipid translocation
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


id: GO:0061094
name: regulation of turning behavior involved in mating
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb]


id: GO:0061095
name: positive regulation of turning behavior involved in mating
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb]


id: GO:0061096
name: negative regulation of turning behavior involved in mating
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb]


id: GO:0061097
name: regulation of protein tyrosine kinase activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb]


id: GO:0061098
name: positive regulation of protein tyrosine kinase activity
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb]


id: GO:0061099
name: negative regulation of protein tyrosine kinase activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb]


id: GO:0061100
name: lung neuroendocrine cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746]


id: GO:0061101
name: neuroendocrine cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph]


id: GO:0061102
name: stomach neuroendocrine cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746]


id: GO:0061103
name: carotid body glomus cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia." [GOC:dph, PMID:6243386]


id: GO:0061104
name: adrenal chromaffin cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles." [GOC:dph]


id: GO:0061105
name: regulation of stomach neuroendocrine cell differentiation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph]


id: GO:0061106
name: negative regulation of stomach neuroendocrine cell differentiation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph]


id: GO:0061107
name: seminal vesicle development
namespace: biological_process
def:
  "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph]


id: GO:0061108
name: seminal vesicle epithelium development
namespace: biological_process
def:
  "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061109
name: dense core granule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph]


id: GO:0061110
name: dense core granule biogenesis
namespace: biological_process
def:
  "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule." [GOC:dph]


id: GO:0061111
name: epithelial-mesenchymal cell signaling involved in lung development
namespace: biological_process
def:
  "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph]


id: GO:0061112
name: negative regulation of bud outgrowth involved in lung branching
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching." [GOC:dph]


id: GO:0061113
name: pancreas morphogenesis
namespace: biological_process
def:
  "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph]


id: GO:0061115
name: lung proximal/distal axis specification
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli." [GOC:dph]


id: GO:0061116
name: ductus venosus closure
namespace: biological_process
def:
  "The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth." [GOC:dph]


id: GO:0061117
name: negative regulation of heart growth
namespace: biological_process
def:
  "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd]


id: GO:0061118
name: regulation of positive chemotaxis to cAMP
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph]


id: GO:0061119
name: regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph, PMID:19684855]


id: GO:0061120
name: regulation of positive chemotaxis to cAMP by DIF-1
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061121
name: regulation of positive chemotaxis to cAMP by DIF-2
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061122
name: positive regulation of positive chemotaxis to cAMP
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph]


id: GO:0061123
name: negative regulation of positive chemotaxis to cAMP
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph]


id: GO:0061124
name: positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph]


id: GO:0061125
name: negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph]


id: GO:0061126
name: positive regulation of positive chemotaxis to cAMP by DIF-1
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061127
name: negative regulation of positive chemotaxis to cAMP by DIF-1
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061128
name: positive regulation of chemotaxis to cAMP by DIF-2
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061129
name: negative regulation of positive chemotaxis to cAMP by DIF-2
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph]


id: GO:0061130
name: pancreatic bud formation
namespace: biological_process
def:
  "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph]


id: GO:0061131
name: pancreas field specification
namespace: biological_process
def:
  "The process in which a specific region of the gut is delineated into the area in which the pancreas will develop." [GOC:dph]


id: GO:0061132
name: pancreas induction
namespace: biological_process
def:
  "The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas." [GOC:dph]


id: GO:0061133
name: endopeptidase activator activity
namespace: molecular_function
def:
  "Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides." [GOC:dph, GOC:tb]


id: GO:0061134
name: peptidase regulator activity
namespace: molecular_function
def:
  "Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds." [GOC:dph, GOC:tb]


id: GO:0061135
name: endopeptidase regulator activity
namespace: molecular_function
def:
  "Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides." [GOC:dph, GOC:tb]


id: GO:0061136
name: regulation of proteasomal protein catabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome." [GOC:dph, GOC:tb]


id: GO:0061137
name: bud dilation
namespace: biological_process
def:
  "The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch." [GOC:dph]


id: GO:0061138
name: morphogenesis of a branching epithelium
namespace: biological_process
def:
  "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph]


id: GO:0061139
name: bud field specification
namespace: biological_process
def:
  "The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:dph]


id: GO:0061140
name: lung secretory cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph]


id: GO:0061141
name: lung ciliated cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains a motile cilium for moving substances released from lung secretory cells." [GOC:dph]


id: GO:0061142
name: mesothelial-mesenchymal cell signaling involved in early lung development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung." [GOC:dph]


id: GO:0061143
name: alveolar primary septum development
namespace: biological_process
def:
  "The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms." [GOC:dph]


id: GO:0061144
name: alveolar secondary septum development
namespace: biological_process
def:
  "The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule." [GOC:dph]


id: GO:0061145
name: lung smooth muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061146
name: Peyer's patch morphogenesis
namespace: biological_process
def:
  "The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes." [GOC:dph]


id: GO:0061147
name: endocardial endothelium development
namespace: biological_process
def:
  "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph]


id: GO:0061148
name: extracellular matrix organization involved in endocardium development
namespace: biological_process
def:
  "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph]


id: GO:0061149
name: BMP signaling pathway involved in ureter morphogenesis
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061150
name: renal system segmentation
namespace: biological_process
def:
  "The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis." [GOC:dph, GOC:yaf]


id: GO:0061151
name: BMP signaling pathway involved in renal system segmentation
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system." [GOC:dph, GOC:yaf]


id: GO:0061152
name: trachea submucosa development
namespace: biological_process
def:
  "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." [GOC:dph, GOC:yaf]


id: GO:0061153
name: trachea gland development
namespace: biological_process
def:
  "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection." [GOC:dph]


id: GO:0061154
name: endothelial tube morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf]


id: GO:0061155
name: pulmonary artery endothelial tube morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf]


id: GO:0061156
name: pulmonary artery morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf]


id: GO:0061157
name: mRNA destabilization
namespace: biological_process
def:
  "Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns." [GOC:dph, GOC:jh]


id: GO:0061158
name: 3'-UTR-mediated mRNA destabilization
namespace: biological_process
def:
  "An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA." [GOC:dph, GOC:jh]


id: GO:0061159
name: establishment of bipolar cell polarity involved in cell morphogenesis
namespace: biological_process
def:
  "The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw]


id: GO:0061160
name: regulation of establishment of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell." [GOC:dph, GOC:vw]


id: GO:0061161
name: positive regulation of establishment of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell." [GOC:dph, GOC:vw]


id: GO:0061162
name: establishment of monopolar cell polarity
namespace: biological_process
def:
  "The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis." [GOC:dph, GOC:vw]


id: GO:0061163
name: endoplasmic reticulum polarization
namespace: biological_process
def:
  "The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell." [GOC:dph, GOC:vw]


id: GO:0061164
name: transitional endoplasmic reticulum polarization at cell division site
namespace: biological_process
def:
  "The endoplasmic reticulum polarization process that results in the structure being polarized at the site of future cell division." [GOC:dph, GOC:vw]


id: GO:0061165
namespace: biological_process
name:
  endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site

def:
  "The process in which endoplasmic reticulum is transiently localized to the site where a cell will divide." [GOC:dph, GOC:vw]


id: GO:0061166
namespace: biological_process
name:
  establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site

def:
  "The directed movement of the endoplasmic reticulum to the site where a cell will divide." [GOC:dph, GOC:vw]


id: GO:0061167
namespace: biological_process
name:
  maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site

def:
  "The process in which the endoplasmic reticulum is maintained at the site of cell division and is prevented from moving elsewhere." [GOC:dph, GOC:vw]


id: GO:0061168
name: regulation of hair follicle placode formation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph]


id: GO:0061169
name: positive regulation of hair placode formation
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph]


id: GO:0061170
name: negative regulation of hair follicle placode formation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph]


id: GO:0061171
name: establishment of bipolar cell polarity
namespace: biological_process
def:
  "The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw]


id: GO:0061172
name: regulation of establishment of bipolar cell polarity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw]


id: GO:0061173
name: positive regulation of establishment of bipolar cell polarity
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity." [GOC:dph, GOC:vw]


id: GO:0061174
name: type I terminal bouton
namespace: cellular_component
def:
  "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc]


id: GO:0061175
name: type II terminal bouton
namespace: cellular_component
def:
  "Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc]


id: GO:0061176
name: type Ib terminal bouton
namespace: cellular_component
def:
  "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons." [GOC:dph, GOC:mc]


id: GO:0061177
name: type Is terminal bouton
namespace: cellular_component
def:
  "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons." [GOC:dph, GOC:mc]


id: GO:0061178
name: regulation of insulin secretion involved in cellular response to glucose stimulus
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph]


id: GO:0061179
name: negative regulation of insulin secretion involved in cellular response to glucose stimulus
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph]


id: GO:0061180
name: mammary gland epithelium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, GOC:yaf]


id: GO:0061181
name: regulation of chondrocyte development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph]


id: GO:0061182
name: negative regulation of chondrocyte development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph]


id: GO:0061183
name: regulation of dermatome development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]


id: GO:0061184
name: positive regulation of dermatome development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]


id: GO:0061185
name: negative regulation of dermatome development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]


id: GO:0061186
name: negative regulation of chromatin silencing at silent mating-type cassette
namespace: biological_process
def:
  "Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin." [GOC:dph, PMID:10388812]


id: GO:0061187
name: regulation of chromatin silencing at rDNA
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin." [GOC:dph, PMID:10388812]


id: GO:0061188
name: negative regulation of chromatin silencing at rDNA
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin." [GOC:dph, PMID:10388812]


id: GO:0061189
name: positive regulation of sclerotome development
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph]


id: GO:0061190
name: regulation of sclerotome development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph]


id: GO:0061191
name: positive regulation of vacuole fusion, non-autophagic
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:dph]


id: GO:0061192
name: negative regulation of vacuole fusion, non-autophagic
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:dph]


id: GO:0061193
name: taste bud development
namespace: biological_process
def:
  "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph]


id: GO:0061194
name: taste bud morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph]


id: GO:0061195
name: taste bud formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph]


id: GO:0061196
name: fungiform papilla development
namespace: biological_process
def:
  "The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph]


id: GO:0061197
name: fungiform papilla morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph]


id: GO:0061198
name: fungiform papilla formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph]


id: GO:0061199
name: striated muscle contraction involved in embryonic body morphogenesis
namespace: biological_process
def:
  "The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology." [GOC:dph, GOC:kmv]


id: GO:0061200
name: clathrin-sculpted gamma-aminobutyric acid transport vesicle
namespace: cellular_component
def:
  "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle." [GOC:dph]


id: GO:0061201
name: clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle." [GOC:dph]


id: GO:0061202
name: clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle." [GOC:dph]


id: GO:0061203
name: striated muscle paramyosin thick filament assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle." [GOC:dph, GOC:kmv]


id: GO:0061205
name: paramesonephric duct development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf]


id: GO:0061206
name: mesonephros morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10]


id: GO:0061207
name: mesonephric juxtaglomerulus cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061208
name: cell differentiation involved in mesonephros development
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061209
name: cell proliferation involved in mesonephros development
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061210
name: cell-cell signaling involved in mesonephros development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]


id: GO:0061211
name: mesonephric collecting duct development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10]


id: GO:0061212
name: mesonephric juxtaglomerular apparatus development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate." [GOC:mtg_kidney_jan10]


id: GO:0061213
name: positive regulation of mesonephros development
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]


id: GO:0061214
name: mesonephric smooth muscle tissue development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]


id: GO:0061215
name: mesonephric nephron development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10]


id: GO:0061216
name: regulation of transcription from RNA polymerase II promoter involved in mesonephros development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061217
name: regulation of mesonephros development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]


id: GO:0061218
name: negative regulation of mesonephros development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]


id: GO:0061219
name: mesonephric mesenchyme development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061220
name: mesonephric macula densa development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus." [GOC:mtg_kidney_jan10]


id: GO:0061221
name: mesonephric mesenchyme morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061222
name: mesonephric mesenchymal cell proliferation involved in mesonephros development
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population." [GOC:mtg_kidney_jan10]


id: GO:0061223
name: mesonephric mesenchymal cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061224
name: mesonephric glomerulus development
namespace: biological_process
def:
  "The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061225
name: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development
namespace: biological_process
def:
  "The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10]


id: GO:0061226
name: proximal/distal pattern formation involved in mesonephric nephron development
namespace: biological_process
def:
  "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end)." [GOC:mtg_kidney_jan10]


id: GO:0061227
name: pattern specification involved in mesonephros development
namespace: biological_process
def:
  "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]


id: GO:0061228
name: mesonephric nephron morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061229
name: mesonephric juxtaglomerulus cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]


id: GO:0061230
name: mesonephric juxtaglomerulus cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell." [GOC:mtg_kidney_jan10]


id: GO:0061231
name: mesonephric glomerulus vasculature development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus." [GOC:mtg_kidney_jan10]


id: GO:0061232
name: mesonephric glomerular epithelium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \\\"feet\\\" that interdigitate with the \\\"feet\\\" of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061233
name: mesonephric glomerular basement membrane development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration." [GOC:mtg_kidney_jan10]


id: GO:0061234
name: mesonephric glomerulus morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061235
name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
namespace: biological_process
def:
  "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]


id: GO:0061236
name: mesonephric comma-shaped body morphogenesis
namespace: biological_process
def:
  "The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061237
name: convergent extension involved in mesonephric nephron morphogenesis
namespace: biological_process
def:
  "The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061238
name: establishment of planar polarity involved in mesonephric nephron morphogenesis
namespace: biological_process
def:
  "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061239
name: mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]


id: GO:0061240
name: mesonephric nephron tubule morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061241
name: mesonephric nephron epithelium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061242
name: mesonephric nephron tubule development
namespace: biological_process
def:
  "The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061243
name: mesonephric renal vesicle morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]


id: GO:0061244
name: mesonephric S-shaped body morphogenesis
namespace: biological_process
def:
  "The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061245
name: establishment or maintenance of bipolar cell polarity
namespace: biological_process
def:
  "Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns." [GOC:dph, GOC:vw]


id: GO:0061246
name: establishment or maintenance of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell." [GOC:dph, GOC:vw]


id: GO:0061247
name: mesonephric glomerular mesangium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus." [GOC:mtg_kidney_jan10]


id: GO:0061248
name: mesonephric glomerulus vasculature morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus." [GOC:mtg_kidney_jan10]


id: GO:0061249
name: mesonephric glomerular capillary formation
namespace: biological_process
def:
  "The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts." [GOC:mtg_kidney_jan10]


id: GO:0061250
name: mesonephric glomerular epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10]


id: GO:0061251
name: mesonephric glomerular epithelial cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10]


id: GO:0061252
name: mesonephric glomerular epithelial cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10]


id: GO:0061253
name: mesonephric glomerular parietal epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10]


id: GO:0061254
name: mesonephric glomerular parietal epithelial cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10]


id: GO:0061255
name: mesonephric glomerular parietal epithelial cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes." [GOC:mtg_kidney_jan10]


id: GO:0061256
name: mesonephric glomerular visceral epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \\\"feet\\\" that interdigitate with the \\\"feet\\\" of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061257
name: mesonephric glomerular visceral epithelial cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \\\"feet\\\" that interdigitate with the \\\"feet\\\" of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061258
name: mesonephric glomerular visceral epithelial cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \\\"feet\\\" that interdigitate with the \\\"feet\\\" of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061259
name: mesonephric glomerular mesangial cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061260
name: mesonephric mesangial cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061261
name: mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
def:
  "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061262
name: mesonephric renal vesicle formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061263
name: mesonephric glomerular mesangial cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]


id: GO:0061264
name: mesonephric glomerular mesangial cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell." [GOC:mtg_kidney_jan10]


id: GO:0061265
name: mesonephric nephron tubule epithelial cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061266
name: mesonephric interstitial fibroblast differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]


id: GO:0061267
name: mesonephric interstitial fibroblast development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]


id: GO:0061268
name: mesonephric interstitial fibroblast fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast." [GOC:mtg_kidney_jan10]


id: GO:0061269
name: mesonephric glomerular mesangial cell proliferation involved in mesonephros development
namespace: biological_process
def:
  "The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population." [GOC:mtg_kidney_jan10]


id: GO:0061270
name: mesonephric intraglomerular mesangial cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis." [GOC:mtg_kidney_jan10]


id: GO:0061271
name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
namespace: biological_process
def:
  "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10]


id: GO:0061272
name: mesonephric connecting tubule development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061273
name: mesonephric distal tubule morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule." [GOC:mtg_kidney_jan10]


id: GO:0061274
name: mesonephric distal tubule development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule." [GOC:mtg_kidney_jan10]


id: GO:0061275
name: mesonephric proximal tubule development
namespace: biological_process
def:
  "The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule." [GOC:mtg_kidney_jan10]


id: GO:0061276
name: mesonephric proximal tubule morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule." [GOC:mtg_kidney_jan10]


id: GO:0061277
name: mesonephric nephron tubule formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]


id: GO:0061278
name: epithelial cell migration involved in mesonephric nephron tubule morphogenesis
namespace: biological_process
def:
  "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10]


id: GO:0061279
name: epithelial cell migration involved in mesonephric distal tubule morphogenesis
namespace: biological_process
def:
  "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10]


id: GO:0061280
name: epithelial cell migration involved in mesonephric proximal tubule morphogenesis
namespace: biological_process
def:
  "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10]


id: GO:0061281
name: specification of mesonephric connecting tubule identity
namespace: biological_process
def:
  "The process in which the connecting tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10]


id: GO:0061282
name: specification of mesonephric nephron tubule identity
namespace: biological_process
def:
  "The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity." [GOC:mtg_kidney_jan10]


id: GO:0061283
name: specification of mesonephric distal tubule identity
namespace: biological_process
def:
  "The process in which the distal tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10]


id: GO:0061284
name: specification of mesonephric proximal tubule identity
namespace: biological_process
def:
  "The process in which the proximal tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10]


id: GO:0061285
name: mesonephric capsule development
namespace: biological_process
def:
  "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10]


id: GO:0061286
name: mesonephric capsule morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]


id: GO:0061287
name: mesonephric capsule formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]


id: GO:0061288
name: mesonephric capsule specification
namespace: biological_process
def:
  "The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:mtg_kidney_jan10]


id: GO:0061289
name: Wnt signaling pathway involved in kidney development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time." [GOC:mtg_kidney_jan10]


id: GO:0061290
name: canonical Wnt signaling pathway involved in metanephric kidney development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10]


id: GO:0061291
name: canonical Wnt signaling pathway involved in ureteric bud branching
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10]


id: GO:0061292
name: canonical Wnt signaling pathway involved in mesonephros development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10]


id: GO:0061293
name: canonical Wnt signaling pathway involved in mesonephric nephron development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10]


id: GO:0061294
name: mesonephric renal vesicle induction
namespace: biological_process
def:
  "Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10]


id: GO:0061295
name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


id: GO:0061296
namespace: biological_process
name:
  negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

def:
  "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


id: GO:0061297
namespace: biological_process
name:
  positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

def:
  "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


id: GO:0061298
name: retina vasculature development in camera-type eye
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph]


id: GO:0061300
name: cerebellum vasculature development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061301
name: cerebellum vasculature morphogenesis
namespace: biological_process
def:
  "The process in which the vasculature of the cerebellum is generated and organized." [GOC:BHF, GOC:dph]


id: GO:0061302
name: smooth muscle cell-matrix adhesion
namespace: biological_process
def:
  "The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules." [GOC:BHF, GOC:dph, PMID:8837777]


id: GO:0061303
name: cornea development in camera-type eye
namespace: biological_process
def:
  "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph]


id: GO:0061304
name: retinal blood vessel morphogenesis
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph]


id: GO:0061305
name: maintenance of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell." [GOC:dph, GOC:vw]


id: GO:0061306
name: DNA strand renaturation involved in double-strand break repair
namespace: biological_process
def:
  "The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair." [GOC:dph]


id: GO:0061307
name: cardiac neural crest cell differentiation involved in heart development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442]


id: GO:0061308
name: cardiac neural crest cell development involved in heart development
namespace: biological_process
def:
  "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart]


id: GO:0061309
name: cardiac neural crest cell development involved in outflow tract morphogenesis
namespace: biological_process
def:
  "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart]


id: GO:0061310
namespace: biological_process
name:
  canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development

def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation." [GOC:dph, GOC:mtg_heart]


id: GO:0061311
name: cell surface receptor signaling pathway involved in heart development
namespace: biological_process
def:
  "Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time." [GOC:dph, GOC:mtg_heart, GOC:signaling]


id: GO:0061312
name: BMP signaling pathway involved in heart development
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time." [GOC:dph, GOC:mtg_heart]


id: GO:0061313
name: fibroblast growth factor receptor signaling pathway involved in heart development
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time." [GOC:mtg_heart]


id: GO:0061314
name: Notch signaling involved in heart development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time." [GOC:mtg_heart]


id: GO:0061315
namespace: biological_process
name:
  canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation

def:
  "The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells." [GOC:mtg_heart]


id: GO:0061316
name: canonical Wnt signaling pathway involved in heart development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_heart]


id: GO:0061317
name: canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_heart, PMID:17576928]


id: GO:0061318
name: renal filtration cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061319
name: nephrocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0002520, GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061320
name: pericardial nephrocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0000474, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135]


id: GO:0061321
name: garland nephrocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0000486, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135]


id: GO:0061322
name: disseminated nephrocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0002524, GOC:19783135, GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061323
name: cell proliferation involved in heart morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart]


id: GO:0061324
namespace: biological_process
name:
  canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

def:
  "The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells." [GOC:dph, GOC:mtg_heart]


id: GO:0061325
name: cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart]


id: GO:0061326
name: renal tubule development
namespace: biological_process
def:
  "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061327
name: anterior Malpighian tubule development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061328
name: posterior Malpighian tubule development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061329
name: Malpighian tubule principal cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061330
name: Malpighian tubule stellate cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061331
name: epithelial cell proliferation involved in Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061332
name: Malpighian tubule bud morphogenesis
namespace: biological_process
def:
  "The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061333
name: renal tubule morphogenesis
namespace: biological_process
def:
  "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061334
name: cell rearrangement involved in Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061335
name: cell growth involved in Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061336
name: cell morphogenesis involved in Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061337
name: cardiac conduction
namespace: biological_process
def:
  "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph]


id: GO:0061338
name: obsolete atrioventricular node impulse conduction delay
namespace: biological_process
def:
  "Obsolete. A heart process that modulates the propagation of the signal that causes the heart muscle to contract." [GOC:dph]


id: GO:0061339
name: establishment or maintenance of monopolar cell polarity
namespace: biological_process
def:
  "Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis." [GOC:dph, GOC:vw]


id: GO:0061340
name: establishment or maintenance of monopolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell." [GOC:dph, GOC:vw]


id: GO:0061341
name: non-canonical Wnt signaling pathway involved in heart development
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time." [GOC:dph, GOC:mtg_heart, PMID:16860783]


id: GO:0061342
name: regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway
namespace: biological_process
def:
  "Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart." [PMID:16860783]


id: GO:0061343
name: cell adhesion involved in heart morphogenesis
namespace: biological_process
def:
  "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783]


id: GO:0061344
name: regulation of cell adhesion involved in heart morphogenesis
namespace: biological_process
def:
  "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783]


id: GO:0061345
name: planar cell polarity pathway involved in cardiac muscle cell fate commitment
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate." [GOC:dph, GOC:mtg_heart, PMID:16860783]


id: GO:0061346
name: planar cell polarity pathway involved in heart morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783]


id: GO:0061347
name: planar cell polarity pathway involved in outflow tract morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart, PMID:19056682]


id: GO:0061348
name: planar cell polarity pathway involved in ventricular septum morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum." [GOC:dph, GOC:mtg_heart, PMID:19056682]


id: GO:0061349
name: planar cell polarity pathway involved in cardiac right atrium morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium." [GOC:dph, GOC:mtg_heart, PMID:19056682]


id: GO:0061350
name: planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue." [GOC:dph, GOC:mtg_heart, PMID:19056682]


id: GO:0061351
name: neural precursor cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf]


id: GO:0061352
name: cell chemotaxis involved in Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061353
name: BMP signaling pathway involved in Malpighian tubule cell chemotaxis
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


id: GO:0061354
name: planar cell polarity pathway involved in pericardium morphogenesis
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium." [GOC:dph, GOC:mtg_heart, PMID:19056682]


id: GO:0061356
name: regulation of Wnt protein secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472]


id: GO:0061357
name: positive regulation of Wnt protein secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472]


id: GO:0061358
name: negative regulation of Wnt protein secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472]


id: GO:0061359
name: regulation of Wnt signaling pathway by Wnt protein secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell." [GOC:bf, GOC:jl, PMID:19223472]


id: GO:0061360
name: optic chiasma development
namespace: biological_process
def:
  "The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature." [GOC:dph]


id: GO:0061361
name: positive regulation of maintenance of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape." [GOC:dph]


id: GO:0061362
name: negative regulation of maintenance of bipolar cell polarity regulating cell shape
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape." [GOC:dph]


id: GO:0061363
name: negative regulation of progesterone biosynthesis involved in luteolysis
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis." [GOC:dph]


id: GO:0061366
name: behavioral response to chemical pain
namespace: biological_process
def:
  "Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus." [GOC:dph]


id: GO:0061367
name: behavioral response to acetic acid induced pain
namespace: biological_process
def:
  "Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus." [GOC:dph]


id: GO:0061368
name: behavioral response to formalin induced pain
namespace: biological_process
def:
  "Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus." [GOC:dph]


id: GO:0061369
name: negative regulation of testicular blood vessel morphogenesis
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle." [GOC:BHF, GOC:dph]


id: GO:0061370
name: testosterone biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5." [GOC:dph, GOC:yaf]


id: GO:0061371
name: determination of heart left/right asymmetry
namespace: biological_process
def:
  "Determination of the asymmetric location of the heart with respect to the left and right halves of the organism." [GOC:dph, GOC:mtg_heart]


id: GO:0061372
name: activin receptor signaling pathway involved in heart jogging
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging." [GOC:dph, GOC:mtg_heart, GOC:signaling]


id: GO:0061373
name: mammillary axonal complex development
namespace: biological_process
def:
  "The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain." [GOC:dph, GOC:yaf, PMID:10662642]


id: GO:0061374
name: mammillothalamic axonal tract development
namespace: biological_process
def:
  "The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit." [GOC:dph, GOC:yaf, PMID:10662642]


id: GO:0061375
name: mammillotectal axonal tract development
namespace: biological_process
def:
  "The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus." [GOC:dph, GOC:yaf, PMID:10662642]


id: GO:0061376
name: mammillotegmental axonal tract development
namespace: biological_process
def:
  "The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons." [GOC:dph, GOC:yaf, PMID:10662642]


id: GO:0061377
name: mammary gland lobule development
namespace: biological_process
def:
  "The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland." [GOC:dph, GOC:yaf]


id: GO:0061378
name: corpora quadrigemina development
namespace: biological_process
def:
  "The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi." [GOC:dph, GOC:yaf]


id: GO:0061379
name: inferior colliculus development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally." [GOC:dph, GOC:yaf]


id: GO:0061380
name: superior colliculus development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain." [GOC:dph, GOC:yaf]


id: GO:0061382
name: Malpighian tubule tip cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells." [GOC:dph, GOC:mtg_kidney_jan10, PMID:7821213]


id: GO:0061383
name: trabecula morphogenesis
namespace: biological_process
def:
  "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]


id: GO:0061384
name: heart trabecula morphogenesis
namespace: biological_process
def:
  "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]


id: GO:0061385
name: fibroblast proliferation involved in heart morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph]


id: GO:0061386
name: closure of optic fissure
namespace: biological_process
def:
  "The closure of the temporary ventral gap in the optic cup that contributes to its shaping." [GOC:dph]


id: GO:0061392
name: regulation of transcription from RNA polymerase II promoter in response to osmotic stress
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, PMID:12086627, PMID:9858577]


id: GO:0061393
name: positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, PMID:12086627, PMID:9858577]


id: GO:0061394
namespace: biological_process
name:
  regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

def:
  "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:dph]


id: GO:0061395
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:dph]


id: GO:0061396
name: regulation of transcription from RNA polymerase II promoter in response to copper ion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus." [GOC:dph]


id: GO:0061397
name: positive regulation of transcription from RNA polymerase II promoter in response to copper ion
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus." [GOC:dph]


id: GO:0061399
name: positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus." [GOC:dph]


id: GO:0061400
name: positive regulation of transcription from RNA polymerase II promoter in response to calcium ion
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus." [GOC:dph]


id: GO:0061401
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph]


id: GO:0061402
name: positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7." [GOC:dph, GOC:go_curators]


id: GO:0061403
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [GOC:dph]


id: GO:0061404
name: positive regulation of transcription from RNA polymerase II promoter in response to increased salt
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph]


id: GO:0061405
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it." [GOC:dph]


id: GO:0061406
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose." [GOC:dph]


id: GO:0061407
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus." [GOC:dph]


id: GO:0061408
name: positive regulation of transcription from RNA polymerase II promoter in response to heat stress
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:dph]


id: GO:0061409
name: positive regulation of transcription from RNA polymerase II promoter in response to freezing
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius." [GOC:dph]


id: GO:0061410
name: positive regulation of transcription from RNA polymerase II promoter in response to ethanol
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus." [GOC:dph]


id: GO:0061411
name: positive regulation of transcription from RNA polymerase II promoter in response to cold
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:dph]


id: GO:0061412
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation

def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids." [GOC:dph]


id: GO:0061413
name: regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source
namespace: biological_process
def:
  "A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338]


id: GO:0061414
namespace: biological_process
name:
  positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

def:
  "A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338]


id: GO:0061415
namespace: biological_process
name:
  negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

def:
  "A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338]


id: GO:0061416
name: regulation of transcription from RNA polymerase II promoter in response to salt stress
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph, PMID:18667581]


id: GO:0061417
namespace: biological_process
name:
  negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress

def:
  "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:dph, PMID:9767597]


id: GO:0061418
name: regulation of transcription from RNA polymerase II promoter in response to hypoxia
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph, PMID:12511571]


id: GO:0061419
name: positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph]


id: GO:0061420
name: regulation of transcription from RNA polymerase II promoter in response to biotin starvation
namespace: biological_process
def:
  "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin." [GOC:dph, PMID:16533810]


id: GO:0061421
name: positive regulation of transcription by oleic acid
namespace: biological_process
def:
  "Any process involving oleic acid that activates or increases the rate of transcription." [GOC:dph, PMID:20395639]


id: GO:0061422
name: positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0." [GOC:dph, PMID:11523797, PMID:15299026, PMID:21749328]


id: GO:0061423
namespace: biological_process
name:
  positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, PMID:11523797]


id: GO:0061424
namespace: biological_process
name:
  positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization." [GOC:dph, PMID:7500953]


id: GO:0061425
namespace: biological_process
name:
  positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process." [GOC:dph, PMID:10608811, PMID:7760841]


id: GO:0061426
namespace: biological_process
name:
  positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter

def:
  "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport." [GOC:dph, PMID:10234785, PMID:10870099]


id: GO:0061427
namespace: biological_process
name:
  negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter

def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process." [GOC:dph, PMID:15302821]


id: GO:0061428
name: negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph, PMID:17785431]


id: GO:0061429
name: positive regulation of transcription from RNA polymerase II promoter by oleic acid
namespace: biological_process
def:
  "Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dph, PMID:20395639]


id: GO:0061430
name: bone trabecula morphogenesis
namespace: biological_process
def:
  "The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:BHF, GOC:dph, GOC:vk]


id: GO:0061431
name: cellular response to methionine
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus." [GOC:dph, PMID:7891681]


id: GO:0061432
name: regulation of transcription from RNA polymerase II promoter in response to methionine
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus." [GOC:dph, PMID:7891681]


id: GO:0061433
name: cellular response to caloric restriction
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake." [GOC:dph, PMID:17914901]


id: GO:0061434
namespace: biological_process
name:
  regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction

def:
  "Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus." [GOC:dph, PMID:17914901]


id: GO:0061435
name: positive regulation of transcription from a mobile element promoter
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter." [GOC:dph, PMID:12230120, PMID:9271107]


id: GO:0061436
name: establishment of skin barrier
namespace: biological_process
def:
  "Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability." [GOC:dph]


id: GO:0061437
name: renal system vasculature development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]


id: GO:0061438
name: renal system vasculature morphogenesis
namespace: biological_process
def:
  "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]


id: GO:0061439
name: kidney vasculature morphogenesis
namespace: biological_process
def:
  "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10]


id: GO:0061440
name: kidney vasculature development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]


id: GO:0061441
name: renal artery morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195]


id: GO:0061442
name: cardiac muscle cell fate determination
namespace: biological_process
def:
  "The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:BHF, GOC:dph]


id: GO:0061443
name: endocardial cushion cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell." [GOC:BHF, GOC:dph]


id: GO:0061444
name: endocardial cushion cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state." [GOC:BHF, GOC:dph]


id: GO:0061445
name: endocardial cushion cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell." [GOC:BHF, GOC:dph]


id: GO:0061446
name: endocardial cushion cell fate determination
namespace: biological_process
def:
  "The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:BHF, GOC:dph]


id: GO:0061447
name: endocardial cushion cell fate specification
namespace: biological_process
def:
  "The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:BHF, GOC:dph]


id: GO:0061448
name: connective tissue development
namespace: biological_process
def:
  "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF]


id: GO:0061449
name: olfactory bulb tufted cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph]


id: GO:0061450
name: trophoblast cell migration
namespace: biological_process
def:
  "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph]


id: GO:0061451
name: retrotrapezoid nucleus development
namespace: biological_process
def:
  "The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration." [GOC:dph]


id: GO:0061452
name: retrotrapezoid nucleus neuron differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus." [GOC:dph]


id: GO:0061453
name: interstitial cell of Cajal differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph]


id: GO:0061454
name: Golgi calcium ion export
namespace: biological_process
def:
  "The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol." [GOC:dph, GOC:tb]


id: GO:0061455
name: integral component of muscle cell projection membrane
namespace: cellular_component
def:
  "The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:dph, GOC:tb]


id: GO:0061456
name: mesenchymal stem cell migration involved in uteric bud morphogenesis
namespace: biological_process
def:
  "The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:dph, GOC:tb]


id: GO:0061457
name: mesonephric cell migration involved in male gonad development
namespace: biological_process
def:
  "The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development." [GOC:dph, GOC:tb]


id: GO:0061458
name: reproductive system development
namespace: biological_process
def:
  "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph]


id: GO:0061459
name: L-arginine transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane." [GOC:dph]


id: GO:0061462
name: protein localization to lysosome
namespace: biological_process
def:
  "A process in which a protein is transported to, or maintained in, a location within a lysosome." [GOC:dph]


id: GO:0061464
name: plasma membrane part of cell-substrate junction.
namespace: cellular_component
def:
  "The part of the plasma membrane that contributes to the structure of a cell-substrate junction." [GOC:dph]


id: GO:0061467
name: basolateral protein localization
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained in, basolateral regions of the cell." [GOC:dph]


id: GO:0061468
name: karyomere
namespace: cellular_component
def:
  "A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division." [GOC:dph, PMID:12734396, PMID:22863006]


id: GO:0061469
name: regulation of type B pancreatic cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph]


id: GO:0061470
name: T follicular helper cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell." [GOC:dph, PMID:21572431]


id: GO:0061471
name: karyomere assembly
namespace: biological_process
def:
  "The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle." [GOC:dph, PMID:9732278]


id: GO:0061472
name: karyomere membrane fusion
namespace: biological_process
def:
  "Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus." [GOC:dph, PMID:2734396]


id: GO:0061473
name: murein tripeptide carboxypeptidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction L-Ala-gamma;-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-&gamma;-D-Glu + meso-diaminopimelate." [GOC:dph, PMID:22970852]


id: GO:0061475
name: cytosolic valyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:dph]


id: GO:0061476
name: response to anticoagulant
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus." [GOC:dph]


id: GO:0061477
name: response to aromatase inhibitor
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus." [GOC:dph]


id: GO:0061478
name: response to platelet aggregation inhibitor
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus." [GOC:dph]


id: GO:0061479
name: response to reverse transcriptase inhibitor
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus." [GOC:dph]


id: GO:0061480
name: response to asparaginase
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus." [GOC:dph]


id: GO:0061481
name: response to TNF agonist
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus." [GOC:dph]


id: GO:0061482
name: response to irinotecan
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus." [GOC:dph]


id: GO:0061483
name: sulfinylpropanyl adenylate synthase
namespace: molecular_function
def:
  "Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate." [GOC:dph, PMID:8346915]


id: GO:0061484
name: hematopoietic stem cell homeostasis
namespace: biological_process
def:
  "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411]


id: GO:0061486
name: high-affinity fructose transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:dph, PMID:10735857]


id: GO:0061487
name: DNA replication initiation from late origin
namespace: biological_process
def:
  "The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase." [GOC:dph, PMID:19221029]


id: GO:0061488
name: adenine import into cell
namespace: biological_process
def:
  "The directed movement of adenine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dph, GOC:mah]


id: GO:0061489
name: guanine import into cell
namespace: biological_process
def:
  "The directed movement of guanine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dph, GOC:mah]


id: GO:0061490
name: glucose import into cell
namespace: biological_process
def:
  "The directed movement of glucose from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dph, GOC:mah]


id: GO:0061491
name: serine import into cell
namespace: biological_process
def:
  "The directed movement of serine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dph, GOC:mah]


id: GO:0061492
name: asymmetric protein localization to old or new spindle pole body
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, PMID:22119525]


id: GO:0061493
name: central plaque of mitotic spindle pole body
namespace: cellular_component
def:
  "One of three laminate structures that form the mitotic spindle pole body; the central plaque is embedded in the nuclear envelope." [GOC:dph]


id: GO:0061494
name: gamma-tubulin large complex, mitotic spindle pole body
namespace: cellular_component
def:
  "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the mitotic spindle pole body." [GOC:dph]


id: GO:0061495
name: gamma-tubulin small complex, mitotic spindle pole body
namespace: cellular_component
def:
  "A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the mitotic spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae." [GOC:dph]


id: GO:0061497
name: inner plaque of mitotic spindle pole body
namespace: cellular_component
def:
  "One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus." [GOC:dph, GOC:vw]


id: GO:0061499
name: outer plaque of mitotic spindle pole body
namespace: cellular_component
def:
  "One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm." [GOC:dph]


id: GO:0061500
name: gene conversion at mating-type locus, termination of copy-synthesis
namespace: biological_process
def:
  "A DNA replication termination process that is part of gene conversion at a mating-type locus and takes place at a specific termination site." [GOC:dph, PMID:10716938]


id: GO:0061502
name: early endosome to recycling endosome transport
namespace: biological_process
def:
  "The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes." [GOC:dph, GOC:kmv, PMID:21474295]


id: GO:0061504
name: cyclic threonylcarbamoyladenosine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules." [PMID:23242255]


id: GO:0061505
name: DNA topoisomerase II activity
namespace: molecular_function
def:
  "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; changes the linking number in multiples of 2." [GOC:dph]


id: GO:0061506
name: DNA topoisomerase type II (ATP-independent) activity
namespace: molecular_function
def:
  "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:dph]


id: GO:0061507
name: cyclic-GMP-AMP binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with cyclic-GMP-AMP (cGAMP) cyclic nucleotide." [GOC:dph, PMID:23258412]


id: GO:0061509
name: asymmetric protein localization to old mitotic spindle pole body
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, GOC:vw]


id: GO:0061510
name: asymmetric protein localization to new mitotic spindle pole body
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, GOC:vw]


id: GO:0061511
name: centriole elongation
namespace: biological_process
def:
  "The centrosome organization process by which a centriole increases in length as part of the process of replication." [GOC:dph, PMID:21576394]


id: GO:0061512
name: protein localization to cilium
namespace: biological_process
def:
  "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph]


id: GO:0061513
name: glucose 6-phosphate:inorganic phosphate antiporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out)." [GOC:dph, PMID:18337460]


id: GO:0061514
name: interleukin-34-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:dph, PMID:18467591]


id: GO:0061515
name: myeloid cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061517
name: macrophage proliferation
namespace: biological_process
def:
  "The expansion of a macrophage population by cell division." [GOC:dph, PMID:12614284, PMID:19466391]


id: GO:0061519
name: macrophage homeostasis
namespace: biological_process
def:
  "The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:dph, PMID:21727904]


id: GO:0061520
name: Langerhans cell differentiation
namespace: biological_process
def:
  "The process in which a precursor cell type acquires the specialized features of a Langerhans cell." [GOC:dph, PMID:22729249]


id: GO:0061521
name: hepatic stellate cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell." [GOC:dph, PMID:9407545]


id: GO:0061522
name: 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA." [GOC:dph]


id: GO:0061524
name: central canal development
namespace: biological_process
def:
  "The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [GOC:cvs, GOC:dph, PMID:23409159]


id: GO:0061525
name: hindgut development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph]


id: GO:0061527
name: dopamine secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter." [GOC:dph]


id: GO:0061529
name: epinephrine secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter." [GOC:dph]


id: GO:0061530
name: aspartate secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter." [GOC:dph]


id: GO:0061532
name: primary amine secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter." [GOC:dph]


id: GO:0061533
name: norepinephrine secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph]


id: GO:0061534
name: gamma-aminobutyric acid secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter." [GOC:dph]


id: GO:0061535
name: glutamate secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter." [GOC:dph]


id: GO:0061537
name: glycine secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter." [GOC:dph]


id: GO:0061538
name: histamine secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter." [GOC:dph]


id: GO:0061540
name: octopamine secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter." [GOC:dph]


id: GO:0061541
name: rhabdomere morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments." [GOC:dph, PMID:22113834]


id: GO:0061542
name: 3-demethylubiquinone-n 3-O-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n." [EC:2.1.1.64, GOC:dph]


id: GO:0061543
name: 3-demethylubiquinone-6 3-O-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-6 = S-adenosyl-L-homocysteine + ubiquinone-6." [GOC:dph]


id: GO:0061544
name: peptide secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter." [GOC:dph]


id: GO:0061546
name: tyramine secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter." [GOC:dph]


id: GO:0061547
name: glycogen synthase activity, transferring glucose-1-phosphate
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate." [GOC:dph, PMID:21356517]


id: GO:0061548
name: ganglion development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061549
name: sympathetic ganglion development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl]


id: GO:0061550
name: cranial ganglion development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061551
name: trigeminal ganglion development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph]


id: GO:0061553
name: ganglion maturation
namespace: biological_process
def:
  "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph]


id: GO:0061554
name: ganglion formation
namespace: biological_process
def:
  "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]


id: GO:0061555
name: ganglion structural organization
namespace: biological_process
def:
  "The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure." [GOC:dph]


id: GO:0061556
name: trigeminal ganglion morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph]


id: GO:0061557
name: trigeminal ganglion maturation
namespace: biological_process
def:
  "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph]


id: GO:0061558
name: cranial ganglion maturation
namespace: biological_process
def:
  "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph]


id: GO:0061559
name: cranial ganglion morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph]


id: GO:0061560
name: cranial ganglion formation
namespace: biological_process
def:
  "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]


id: GO:0061561
name: trigeminal ganglion formation
namespace: biological_process
def:
  "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]


id: GO:0061562
name: cranial ganglion structural organization
namespace: biological_process
def:
  "The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure." [GOC:dph]


id: GO:0061563
name: trigeminal ganglion structural organization
namespace: biological_process
def:
  "The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure." [GOC:dph]


id: GO:0061564
name: axon development
namespace: biological_process
def:
  "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." [GOC:dph, GOC:pg, GOC:pr]


id: GO:0061565
name: dAMP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP." [GOC:dph, PMID:23416111]


id: GO:0061566
name: CMP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP." [GOC:dph, PMID:23416111]


id: GO:0061567
name: dCMP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP." [GOC:dph, PMID:23416111]


id: GO:0061568
name: GDP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP." [GOC:dph, PMID:23416111]


id: GO:0061569
name: UDP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP." [GOC:dph, PMID:23416111]


id: GO:0061570
name: dCDP phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group into dCDP to produce a dCTP." [GOC:dph, PMID:23416111]


id: GO:0061572
name: actin filament bundle organization
namespace: biological_process
def:
  "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph]


id: GO:0061573
name: actin filament bundle retrograde transport
namespace: biological_process
def:
  "A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell." [GOC:dph]


id: GO:0061574
name: ASAP complex
namespace: cellular_component
def:
  "A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1." [GOC:dph, PMID:12665594, PMID:16314458, PMID:22388736]


id: GO:0061575
name: cyclin-dependent protein serine/threonine kinase activator activity
namespace: molecular_function
def:
  "Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase." [GOC:dph, PMID:2569363, PMID:3322810]


id: GO:0061576
name: acyl-CoA ceramide synthase complex
namespace: cellular_component
def:
  "A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1." [GOC:dph, PMID:15692566]


id: GO:0061577
name: generation of L-type calcium current
namespace: biological_process
def:
  "A process in which a calcium ion is transported from one side of a membrane to the other by means of an L-type calcium channel." [GOC:dph]


id: GO:0061578
name: Lys63-specific deubiquitinase activity
namespace: molecular_function
def:
  "Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein." [GOC:dph, GOC:pg, PMID:18313383]


id: GO:0061579
name: N-acyl homoserine lactone synthase activity
namespace: molecular_function
def:
  "Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone." [GOC:dph]


id: GO:0061580
name: colon epithelial cell migration
namespace: biological_process
def:
  "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]


id: GO:0061581
name: corneal epithelial cell migration
namespace: biological_process
def:
  "The orderly movement of a corneal  epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]


id: GO:0061582
name: intestinal epithelial cell migration
namespace: biological_process
def:
  "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]


id: GO:0061583
name: colon epithelial cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [GOC:dph]


id: GO:0061585
name: hypocretin secretion, neurotransmission
namespace: biological_process
def:
  "The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter." [GOC:dph]


id: GO:0061586
name: positive regulation of transcription by transcription factor localization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor." [GOC:dph]


id: GO:0061587
name: transfer RNA gene-mediated silencing
namespace: biological_process
def:
  "The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes." [GOC:dph, PMID:23707796]


id: GO:0061588
name: calcium activated phospholipid scrambling
namespace: biological_process
def:
  "The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839]


id: GO:0061589
name: calcium activated phosphatidylserine scrambling
namespace: biological_process
def:
  "The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839]


id: GO:0061590
name: calcium activated phosphatidylcholine scrambling
namespace: biological_process
def:
  "The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839]


id: GO:0061591
name: calcium activated galactosylceramide scrambling
namespace: biological_process
def:
  "The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839]


id: GO:0061592
name: phosphatidylserine exposure on osteoblast involved in bone mineralization
namespace: biological_process
def:
  "A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization." [GOC:krc, PMID:22936354]


id: GO:0061594
name: 6-deoxy-6-sulfofructose kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP." [PMID:24463506]


id: GO:0061595
name: 6-deoxy-6-sulfofructose-1-phosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate." [PMID:24463506]


id: GO:0061596
name: 3-sulfolactaldehyde reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+." [GOC:dph, PMID:24463506]


id: GO:0061597
name: cyclic pyranopterin monophosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate." [EC:4.1.99.18, GOC:dph, PMID:18154309]


id: GO:0061598
name: molybdopterin adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin." [EC:2.7.7.75, GOC:dph]


id: GO:0061599
name: molybdopterin molybdotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP." [EC:2.10.1.1, GOC:dph]


id: GO:0061602
name: molybdenum cofactor cytidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor." [EC:2.7.7.76, GOC:dph]


id: GO:0061603
name: molybdenum cofactor guanylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor." [EC:2.7.7.77, GOC:dph]


id: GO:0061604
name: molybdopterin-synthase sulfurtransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase." [EC:2.8.1.11, GOC:dph, PMID:18154309, PMID:22370186]


id: GO:0061605
name: molybdopterin-synthase adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP." [EC:2.7.7.80, GOC:dph, PMID:18154309, PMID:22370186]


id: GO:0061606
name: N-terminal protein amino acid propionylation
namespace: biological_process
def:
  "The propionylation of the N-terminal amino acid of proteins." [GOC:dph, PMID:17267393, PMID:23043182]


id: GO:0061607
name: peptide alpha-N-propionyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein." [GOC:dph, PMID:23043182]


id: GO:0061608
name: nuclear import signal receptor activity
namespace: molecular_function
def:
  "Combining with a nuclear import signal (NIS) to mediate transport of the NIS-containing protein through the nuclear pore to the nucleus." [GOC:dph, GOC:vw]


id: GO:0061609
name: fructose-1-phosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde." [GOC:dph, GOC:glycolysis, ISBN:0201090910, RHEA:30854]


id: GO:0061610
name: glycerol to glycerone phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate." [GOC:dph, ISBN:0201090910]


id: GO:0061611
name: mannose to fructose-6-phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061612
name: galactose to glucose-1-phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061613
name: glycolytic process from glycerol
namespace: biological_process
def:
  "The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH." [GOC:dph, ISBN:0201090910]


id: GO:0061614
name: pri-miRNA transcription from RNA polymerase II promoter
namespace: biological_process
def:
  "The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation." [GOC:dph, GOC:kmv, PMID:18778799]


id: GO:0061615
name: glycolytic process through fructose-6-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061616
name: glycolytic process from fructose through fructose-6-phosphate
namespace: biological_process
def:
  "The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061617
name: MICOS complex
namespace: cellular_component
def:
  "Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60." [GOC:dph, PMID:21944719, PMID:21987634, PMID:22009199, PMID:24687277]


id: GO:0061618
name: sublamina densa
namespace: cellular_component
def:
  "The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers." [GOC:BHF, PMID:15623520]


id: GO:0061619
name: glycolytic process from mannose through fructose-6-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061620
name: glycolytic process through glucose-6-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061621
name: canonical glycolysis
namespace: biological_process
def:
  "The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the  chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910, ISBN:0879010479]


id: GO:0061622
name: glycolytic process through glucose-1-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910]


id: GO:0061623
name: glycolytic process from galactose
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910]


id: GO:0061624
name: fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate." [GOC:dph, ISBN:0201090910]


id: GO:0061625
name: glycolytic process through fructose-1-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910]


id: GO:0061626
name: pharyngeal arch artery morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914]


id: GO:0061627
name: S-methylmethionine-homocysteine S-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+." [EC:2.1.1.10, GOC:BHF, GOC:dph]


id: GO:0061628
name: H3K27me3 modified histone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 27 has been modified by trimethylation." [GOC:dph, PMID:23948251]


id: GO:0061629
name: RNA polymerase II sequence-specific DNA binding transcription factor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription." [GOC:dph, GOC:vw]


id: GO:0061630
name: ubiquitin protein ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S --> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate. Note that this may include the extension of ubiquitin chains." [GOC:BioGRID, GOC:dph]


id: GO:0061631
name: ubiquitin conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue." [GOC:BioGRID, GOC:dph]


id: GO:0061632
name: RNA lariat debranching enzyme activator activity
namespace: molecular_function
def:
  "Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide." [GOC:dph, PMID:24919400]


id: GO:0061633
name: transport-coupled glycolytic process through glucose-6-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport." [GOC:dph]


id: GO:0061634
name: alpha-D-xyloside xylohydrolase
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose." [EC:3.2.1.177]


id: GO:0061635
name: regulation of protein complex stability
namespace: biological_process
def:
  "Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly." [GOC:dph]


id: GO:0061636
name: mitotic anaphase-promoting complex activator activity
namespace: molecular_function
def:
  "Increases the activity of a mitotic anaphase promoting complex, an ubiquitin-protein transferase activity that regulates the mitotic metaphase/anaphase transition." [GOC:dph]


id: GO:0061637
name: mitotic anaphase-promoting complex inhibitor activity
namespace: molecular_function
def:
  "Prevents the activation of a mitotic anaphase promoting complex, a ubiquitin-protein transferase activity that regulates mitotic cell cycle transitions." [GOC:dph, GOC:vw]


id: GO:0061638
name: CENP-A containing chromatin
namespace: cellular_component
def:
  "The specialized chromatin located the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment." [GOC:vw, PMID:20206496, PMID:22729156]


id: GO:0061639
name: Cdv-dependent cytokinesis
namespace: biological_process
def:
  "A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells." [GOC:dph, PMID:18987308]


id: GO:0061640
name: cytoskeleton-dependent cytokinesis
namespace: biological_process
def:
  "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." [GOC:dph]


id: GO:0061641
name: CENP-A containing chromatin organization
namespace: biological_process
def:
  "Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin." [GOC:dph]


id: GO:0061642
name: chemoattraction of axon
namespace: biological_process
def:
  "The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal." [GOC:dph, GOC:krc]


id: GO:0061643
name: chemorepulsion of axon
namespace: biological_process
def:
  "The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." [GOC:dph, GOC:krc]


id: GO:0061644
name: protein localization to CENP-A containing chromatin
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin." [GOC:dph, GOC:vw]


id: GO:0061645
name: endocytic patch
namespace: cellular_component
def:
  "The part of the cell cortex consisting of  an aggregation of proteins that will give rise to an endocytic vesicle." [GOC:dph, PMID:22949647]


id: GO:0061646
name: positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter." [GOC:pad, GOC:PARL]


id: GO:0061648
name: tooth replacement
namespace: biological_process
def:
  "The process whose specific outcome is the replacement of an existing tooth with another tooth." [GOC:dph, PMID:15170864]


id: GO:0061649
name: ubiquitinated histone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:dph, PMID:24526689]


id: GO:0061650
name: ubiquitin-like protein conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061651
name: Atg12 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061652
name: FAT10 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061653
name: ISG15 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061654
name: NEDD8 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061655
name: Pup conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061656
name: SUMO conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061657
name: UFM1 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061658
name: URM1 conjugating enzyme activity
namespace: molecular_function
def:
  "Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue." [GOC:dph]


id: GO:0061659
name: ubiquitin-like protein ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061660
name: Atg12 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061661
name: FAT10 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061662
name: ISG15 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061663
name: NEDD8 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061664
name: Pup ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061665
name: SUMO ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061666
name: UFM1 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061667
name: URM1 ligase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]


id: GO:0061668
name: mitochondrial ribosome assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits." [GOC:dph]


id: GO:0061669
name: spontaneous neurotransmitter secretion
namespace: biological_process
def:
  "Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential." [GOC:dph, GOC:pad, GOC:PARL, PMID:21334193]


id: GO:0061670
name: evoked neurotransmitter secretion
namespace: biological_process
def:
  "Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential." [GOC:dph, GOC:pad, GOC:PARL, PMID:21334193]


id: GO:0061671
name: Cbp3p-Cbp6 complex
namespace: cellular_component
def:
  "A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly." [GOC:dph, GOC:rb, PMID:21670217]


id: GO:0061672
name: glutathione hydrolase complex
namespace: cellular_component
def:
  "Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly." [GOC:dph]


id: GO:0061673
name: mitotic spindle astral microtubule
namespace: cellular_component
def:
  "Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GOC:dph]


id: GO:0061674
name: gap filling involved in double-strand break repair via nonhomologous end joining
namespace: biological_process
def:
  "Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining." [GOC:dph]


id: GO:0061675
name: RBL family protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose." [PMID:22312473]


id: GO:0061676
name: importin-alpha family protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any member of the importin-alpha family." [PMID:15350979, PMID:17170104, PMID:23734157]


id: GO:0061677
name: 2-dehydro-3-deoxy-D-gluconate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde." [EC:4.1.2.51, GOC:dph]


id: GO:0061678
name: Entner-Doudoroff pathway
namespace: biological_process
def:
  "A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate." [GOC:dph, PMID:12921536]


id: GO:0061679
name: Entner-Doudoroff pathway through gluconate
namespace: biological_process
def:
  "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate." [GOC:dph, PMID:12921536]


id: GO:0061680
name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde
namespace: biological_process
def:
  "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde." [GOC:dph, MetaCyc:ENTNER-DOUDOROFF-PWY-II, PMID:12921536]


id: GO:0061681
name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate
namespace: biological_process
def:
  "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate." [GOC:dph, MetaCyc:ENTNER-DOUFDOROFF-PWY-III, PMID:12921536]


id: GO:0061682
name: seminal vesicle morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph]


id: GO:0061683
name: branching involved in seminal vesicle morphogenesis
namespace: biological_process
def:
  "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376]


id: GO:0061684
name: chaperone-mediated autophagy
namespace: biological_process
def:
  "The autophagy process which begins when chaperones and co-chaperones recognize a KFERQ-related motif and unfold the substrate protein. The process ends with the catabolism of the protein in the lysosome." [GOC:pad, GOC:PARL, PMID:22743996]


id: GO:0061685
name: diphthine methylesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol." [GOC:dph, PMID:24739148, RHEA:42659]


id: GO:0061686
name: hercynylcysteine sulfoxide synthase
namespace: molecular_function
def:
  "Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine + O2 <=> hercynylcysteine sulfoxide + H2O." [GOC:dph, PMID:28577]


id: GO:0061687
name: detoxification of inorganic compound
namespace: biological_process
def:
  "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw]


id: GO:0061688
name: glycolytic process via Entner-Doudoroff Pathway
namespace: biological_process
def:
  "A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes." [GOC:dph, PMID:9657988]


id: GO:0061689
name: tricellular tight junction
namespace: cellular_component
def:
  "An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet." [GOC:dk, GOC:dph, PMID:22520461, PMID:25822906]


id: GO:0061690
name: lipoamidase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein." [GOC:dph, PMID:14086741]


id: GO:0061691
name: detoxification of hydrogen peroxide
namespace: biological_process
def:
  "Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration." [GOC:dph]


id: GO:0061692
name: cellular detoxification of hydrogen peroxide
namespace: biological_process
def:
  "Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration." [GOC:dph, GOC:vw]


id: GO:0061693
name: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine." [EC:2.7.8.37, GOC:dph, PMID:22089136]


id: GO:0061694
name: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
namespace: cellular_component
def:
  "A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity." [GOC:dph, PMID:22089136]


id: GO:0061695
name: transferase complex, transferring phosphorus-containing groups
namespace: cellular_component
def:
  "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph]


id: GO:0061696
name: pituitary gonadotropin complex
namespace: cellular_component
def:
  "A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function." [GOC:dph, PMID:11420129]


id: GO:0061697
name: protein-glutaryllysine deglutarylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: protein-glutaryllysine + H2O => protein-lysine + glutarate. This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide." [GOC:dph, PMID:24703693]


id: GO:0061698
name: protein deglutarylation
namespace: biological_process
def:
  "The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein." [GOC:dph, PMID:24703693]


id: GO:0061699
name: peptidyl-lysine deglutarylation
namespace: biological_process
def:
  "The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein." [GOC:dph, PMID:24703693]


id: GO:0061700
name: GATOR2 complex
namespace: cellular_component
def:
  "A multiprotein subcomplex of GATOR that regulates mTOR signaling by interacting with the Rag GTPases. In humans this complex consists of Mios, WDR24, WDR59, Seh1L, Sec13." [GOC:rb, PMID:23723238]


id: GO:0061701
name: bacterial outer membrane vesicle
namespace: cellular_component
def:
  "A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes." [GOC:dph, GOC:pr, PMID:20596524]


id: GO:0061703
name: pyroptosome complex
namespace: cellular_component
def:
  "A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis." [GOC:dph, PMID:17599095]


id: GO:0061704
name: glycolytic process from sucrose
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules." [GOC:dph, GOC:glycolysis, PMID:15012287]


id: GO:0061705
name: sucrose catabolic process to fructose-6-phosphate through glucose and fructose
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates." [GOC:dph, GOC:glycolysis, MetaCyc:PWY-621, PMID:15012287]


id: GO:0061706
name: glycolytic process from sucrose through glucose and fructose
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules." [GOC:dph, GOC:glycolysis, MetaCyc:PWY-1042, PMID:15012287]


id: GO:0061707
name: extracellular exosome macropinocytosis
namespace: biological_process
def:
  "The single-organism macropinocytosis process that results in the uptake of an extracellular exosome." [GOC:dph, PMID:24951588]


id: GO:0061708
name: tRNA-5-taurinomethyluridine 2-sulfurtransferase
namespace: molecular_function
def:
  "Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+." [GOC:dph, PMID:15509579]


id: GO:0061709
name: reticulophagy
namespace: biological_process
def:
  "The autophagic process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions." [GOC:autophagy, GOC:dph, PMID:22481944, PMID:24060720, PMID:26040717]


id: GO:0061710
name: L-threonylcarbamoyladenylate synthase
namespace: molecular_function
def:
  "Catalysis of the reaction:  L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O." [EC:2.7.7.87]


id: GO:0061711
name: N(6)-L-threonylcarbamoyladenine synthase
namespace: molecular_function
def:
  "Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA." [EC:2.3.1.234]


id: GO:0061712
name: tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
namespace: molecular_function
def:
  "Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine." [EC:2.8.4.5]


id: GO:0061713
name: anterior neural tube closure
namespace: biological_process
def:
  "The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline." [GOC:BHF, GOC:dph, GOC:hal, PMID:17286298]


id: GO:0061714
name: folic acid receptor activity
namespace: molecular_function
def:
  "Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis." [GOC:BHF, GOC:hal]


id: GO:0061715
name: miRNA 2'-O-methylation
namespace: biological_process
def:
  "The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:20705645]


id: GO:0061716
name: miRNA export from nucleus
namespace: biological_process
def:
  "The directed movement of a processed miRNA from the nucleus to the cytoplasm." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756]


id: GO:0061717
name: miRNA transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of cleaved miRNAs between the nucleus and the cytoplasm of a cell." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756]


id: GO:0061718
name: glucose catabolic process to pyruvate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate." [GOC:dph]


id: GO:0061719
name: glucose catabolic process to pyruvate utilizing ADP
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions." [GOC:dph, MetaCyc:P341-PWY]


id: GO:0061720
name: 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)." [GOC:dph, PMID:24463506]


id: GO:0061721
name: 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-)." [GOC:dph, PMID:14602517, PMID:24463506]


id: GO:0061722
name: sulphoglycolysis
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate." [GOC:dph, PMID:24463506]


id: GO:0061723
name: glycophagy
namespace: biological_process
def:
  "The autophagic process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions." [PMID:21893048]


id: GO:0061724
name: lipophagy
namespace: biological_process
def:
  "The autophagic process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions." [GOC:autophagy, PMID:23708524, PMID:26076903]


id: GO:0061725
name: cytosolic lipolysis
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases." [GOC:autophagy]


id: GO:0061726
name: mitochondrion disassembly
namespace: biological_process
def:
  "The disaggregation of a mitochondrion into its constituent components." [GOC:autophagy, PMID:25009776]


id: GO:0061727
name: methylglyoxal catabolic process to lactate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate." [GOC:dph, PMID:2198020]


id: GO:0061728
name: GDP-mannose biosynthetic process from mannose
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose." [GOC:dph, PMID:16339137, PMID:24218558]


id: GO:0061729
name: GDP-mannose biosynthetic process from fructose-6-phosphate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate." [GOC:dph, PMID:16339137]


id: GO:0061730
name: C-rich strand telomeric DNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with C-rich, single-stranded, telomere-associated DNA." [GOC:dph, GOC:kmv, PMID:18329362]


id: GO:0061731
name: ribonucleoside-diphosphate reductase activity
namespace: molecular_function
def:
  "Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor." [GOC:dph, GOC:vw, PMID:16756507]


id: GO:0061732
name: mitochondrial acetyl-CoA biosynthetic process from pyruvate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA." [GOC:dph, ISBN:0201090910]


id: GO:0061733
name: peptide-lysine-N-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide." [GOC:dph]


id: GO:0061734
name: parkin-mediated mitophagy in response to mitochondrial depolarization
namespace: biological_process
def:
  "The macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190]


id: GO:0061735
name: dynamin-like protein-mediated mitophagy in response to mitochondrial depolarization
namespace: biological_process
def:
  "The macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a dynamin-like molecule." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190]


id: GO:0061736
name: engulfment of target by autophagosome
namespace: biological_process
def:
  "The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL]


id: GO:0061737
name: leukotriene signaling pathway
namespace: biological_process
def:
  "A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:dph, PMID:21771892]


id: GO:0061738
name: late endosomal microautophagy
namespace: biological_process
def:
  "The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:21238931]


id: GO:0061739
name: protein lipidation involved in autophagosome assembly
namespace: biological_process
def:
  "The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly." [GOC:autophagy, GOC:dph, PMID:11096062, PMID:11100732, PMID:15277523]


id: GO:0061740
name: protein targeting to lysosome involved in chaperone-mediated autophagy
namespace: biological_process
def:
  "The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor." [GOC:dph, GOC:pad, GOC:PARL, PMID:22748206]


id: GO:0061741
name: chaperone-mediated protein transport involved in chaperone-mediated autophagy
namespace: biological_process
def:
  "The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:22748206]


id: GO:0061742
name: chaperone-mediated autophagy translocation complex
namespace: cellular_component
def:
  "A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy." [GOC:dph, GOC:pad, GOC:PARL, PMID:20797626]


id: GO:0061743
name: motor learning
namespace: biological_process
def:
  "Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience." [GOC:bf, GOC:PARL, Wikipedia:Motor_learning]


id: GO:0061744
name: motor behavior
namespace: biological_process
def:
  "The specific neuromuscular movement of a single organism in response to external or internal stimuli." [GOC:bf, GOC:PARL, PMID:25318560]


id: GO:0061745
name: GTPase activity, coupled
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction directly drives some other reaction." [GOC:dph, PMID:26277776]


id: GO:0061746
name: single-stranded DNA-dependent GTPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction." [GOC:dph, PMID:26277776]


id: GO:0061747
name: CTPase activity, coupled
namespace: molecular_function
def:
  "Catalysis of the reaction: CTP + H2O = CDP + phosphate; this reaction directly drives some other reaction." [GOC:dph, PMID:26277776]


id: GO:0061748
name: single-stranded DNA-dependent CTPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CTP + H2O = CDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction." [GOC:dph, PMID:26277776]


id: GO:0061749
name: forked DNA-dependent helicase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA." [GOC:dph, PMID:26277776]


id: GO:0061750
name: acid sphingomyelin phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment." [GOC:dph, PMID:26493087]


id: GO:0061751
name: neutral sphingomyelin phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment." [GOC:dph, PMID:26493087]


id: GO:0061752
name: telomeric repeat-containing RNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats." [GOC:BHF, GOC:BHF_telomere, GOC:dph, GOC:jbu, PMID:20655916]


id: GO:0061753
name: substrate localization to autophagosome
namespace: biological_process
def:
  "The localization process by which an autophagic substrate is delivered to a forming autophagosome." [GOC:dph, GOC:pad, GOC:PARL, PMID:23545414]


id: GO:0061754
name: negative regulation of circulating fibrinogen levels
namespace: biological_process
def:
  "Any process that reduces the quantity of fibrinogen circulating in the bloodstream." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:20570858]


id: GO:0061755
name: positive regulation of circulating fibrinogen levels
namespace: biological_process
def:
  "Any process that increases the quantity of fibrinogen circulating in the bloodstream." [GOC:bf, GOC:BHF, GOC:BHF_miRNA, PMID:20570858]


id: GO:0061756
name: leukocyte adhesion to vascular endothelial cell
namespace: biological_process
def:
  "The attachment of a leukocyte to vascular endothelial cell via adhesion molecules." [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:23897866]


id: GO:0061757
name: leukocyte adhesion to arterial endothelial cell
namespace: biological_process
def:
  "The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules." [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:22267480]


id: GO:0065001
name: specification of axis polarity
namespace: biological_process
def:
  "The pattern specification process in which the polarity of a body or organ axis is established and maintained." [GOC:mah]


id: GO:0065002
name: intracellular protein transmembrane transport
namespace: biological_process
def:
  "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete]


id: GO:0065003
name: macromolecular complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of macromolecules to form a complex." [GOC:jl]


id: GO:0065004
name: protein-DNA complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl]


id: GO:0065005
name: protein-lipid complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex." [GOC:jl]


id: GO:0065006
name: protein-carbohydrate complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of proteins and carbohydrates to form a protein-carbohydrate complex." [GOC:jl]


id: GO:0065007
name: biological regulation
namespace: biological_process
def:
  "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]


id: GO:0065008
name: regulation of biological quality
namespace: biological_process
def:
  "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]


id: GO:0065009
name: regulation of molecular function
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete]


id: GO:0065010
name: extracellular membrane-bounded organelle
namespace: cellular_component
def:
  "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete]


id: GO:0070001
name: aspartic-type peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0070002
name: glutamic-type peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0070003
name: threonine-type peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0070004
name: cysteine-type exopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE]


id: GO:0070005
name: cysteine-type aminopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0070006
name: metalloaminopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0070007
name: glutamic-type endopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE]


id: GO:0070008
name: serine-type exopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE, ISBN:0716720094]


id: GO:0070009
name: serine-type aminopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094]


id: GO:0070012
name: oligopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds." [GOC:mah, ISBN:0198506732]


id: GO:0070014
name: sucrase-isomaltase complex
namespace: cellular_component
def:
  "A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities." [PMID:3366777]


id: GO:0070016
name: armadillo repeat domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation." [GOC:BHF, GOC:mah, GOC:vk, InterPro:IPR000225]


id: GO:0070017
name: alphav-beta3 integrin-thrombospondin complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin." [PMID:2478219]


id: GO:0070018
name: transforming growth factor beta type I receptor homodimeric complex
namespace: cellular_component
def:
  "A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers." [Reactome:REACT_7737]


id: GO:0070019
name: transforming growth factor beta type II receptor homodimeric complex
namespace: cellular_component
def:
  "A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers." [Reactome:REACT_7415]


id: GO:0070020
name: transforming growth factor beta1-type II receptor complex
namespace: cellular_component
def:
  "A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer." [Reactome:REACT_7218]


id: GO:0070021
name: transforming growth factor beta1-type II receptor-type I receptor complex
namespace: cellular_component
def:
  "A protein complex that is formed by the association of a ligand-bound TGF-beta type II receptor dimer with a TGF-beta type I receptor dimer." [Reactome:REACT_7425]


id: GO:0070022
name: transforming growth factor beta receptor homodimeric complex
namespace: cellular_component
def:
  "A homodimeric receptor complex that consists of two TGF-beta receptor monomers." [GOC:mah, Reactome:REACT_7415, Reactome:REACT_7737]


id: GO:0070023
name: interleukin-12-interleukin-12 receptor complex
namespace: cellular_component
def:
  "A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer." [PMID:11900991]


id: GO:0070024
name: CD19-Vav-PIK3R1 complex
namespace: cellular_component
def:
  "A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K)." [PMID:7528218]


id: GO:0070027
name: carbon monoxide sensor activity
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO)." [GOC:ecd]


id: GO:0070028
name: regulation of transcription by carbon monoxide
namespace: biological_process
def:
  "Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription." [GOC:ecd]


id: GO:0070029
name: alphav-beta3 integrin-osteopontin complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin." [PMID:7532190]


id: GO:0070030
name: alphav-beta1 integrin-osteopontin complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin." [PMID:7592829]


id: GO:0070031
name: alphav-beta5 integrin-osteopontin complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin." [PMID:7592829]


id: GO:0070032
name: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof)." [PMID:7553862]


id: GO:0070033
name: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof)." [PMID:7553862]


id: GO:0070034
name: telomerase RNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the telomerase RNA template." [GOC:krc, PMID:16884717]


id: GO:0070035
name: purine NTP-dependent helicase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix." [GOC:mah]


id: GO:0070036
name: GTP-dependent helicase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix." [GOC:mah]


id: GO:0070037
name: rRNA (pseudouridine) methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule." [GOC:imk, GOC:mah]


id: GO:0070038
name: rRNA (pseudouridine-N3-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine." [GOC:imk, GOC:mah]


id: GO:0070039
name: rRNA (guanosine-2'-O-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine." [GOC:imk, GOC:mah]


id: GO:0070040
name: rRNA (adenine-C2-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA." [GOC:imk, PMID:20007606, PMID:20184321, PMID:21368151, PMID:21415317, PMID:21527678]


id: GO:0070041
name: rRNA (uridine-C5-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine." [GOC:imk, GOC:mah]


id: GO:0070042
name: rRNA (uridine-N3-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine." [GOC:imk, GOC:mah]


id: GO:0070043
name: rRNA (guanine-N7-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine." [GOC:imk, GOC:mah]


id: GO:0070044
name: synaptobrevin 2-SNAP-25-syntaxin-1a complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof)." [PMID:10336434]


id: GO:0070045
name: synaptobrevin 2-SNAP-25-syntaxin-2 complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof)." [PMID:10336434]


id: GO:0070046
name: synaptobrevin 2-SNAP-25-syntaxin-3 complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof)." [PMID:10336434]


id: GO:0070047
name: synaptobrevin 2-SNAP-25-syntaxin-4 complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof)." [PMID:10336434]


id: GO:0070048
name: endobrevin-SNAP-25-syntaxin-1a complex
namespace: cellular_component
def:
  "A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof)." [PMID:10336434]


id: GO:0070049
name: endobrevin-SNAP-25-syntaxin-2 complex
namespace: cellular_component
def:
  "A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof)." [PMID:10336434]


id: GO:0070050
name: neuron cellular homeostasis
namespace: biological_process
def:
  "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah]


id: GO:0070051
name: fibrinogen binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade." [GOC:BHF, GOC:mah, GOC:vk]


id: GO:0070053
name: thrombospondin receptor activity
namespace: molecular_function
def:
  "Combining with thrombospondin and transmitting the signal to initiate a change in cell activity." [GOC:BHF, GOC:signaling, GOC:vk]


id: GO:0070054
name: mRNA splicing, via endonucleolytic cleavage and ligation
namespace: biological_process
def:
  "Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons." [GOC:krc, GOC:mah]


id: GO:0070055
name: mRNA endonucleolytic cleavage involved in unfolded protein response
namespace: biological_process
def:
  "The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response." [GOC:bf, GOC:krc, GOC:mah, PMID:10357823]


id: GO:0070056
name: prospore membrane leading edge
namespace: cellular_component
def:
  "The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization." [GOC:mah, PMID:14702385]


id: GO:0070057
name: prospore membrane spindle pole body attachment site
namespace: cellular_component
def:
  "The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus." [GOC:mah, PMID:14702385]


id: GO:0070058
name: tRNA gene clustering
namespace: biological_process
def:
  "The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae." [GOC:jh, GOC:mah, PMID:18708579]


id: GO:0070059
name: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
namespace: biological_process
def:
  "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:mah, GOC:mtg_apoptosis, PMID:18701708]


id: GO:0070060
name: 'de novo' actin filament nucleation
namespace: biological_process
def:
  "The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament." [GOC:mah, PMID:17477841]


id: GO:0070061
name: fructose binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose." [CHEBI:28757, GOC:BHF, GOC:mah]


id: GO:0070062
name: extracellular exosome
namespace: cellular_component
def:
  "A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]


id: GO:0070063
name: RNA polymerase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an RNA polymerase molecule or complex." [GOC:BHF, GOC:mah, GOC:txnOH]


id: GO:0070064
name: proline-rich region binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein." [GOC:mah]


id: GO:0070065
name: cellubrevin-VAMP4-syntaxin-16 complex
namespace: cellular_component
def:
  "A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof)." [PMID:11839770]


id: GO:0070066
name: cellubrevin-VAMP4-endobrevin-syntaxin-6 complex
namespace: cellular_component
def:
  "A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof)." [PMID:11839770]


id: GO:0070067
name: syntaxin-6-syntaxin-16-Vti1a complex
namespace: cellular_component
def:
  "A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof)." [PMID:11839770]


id: GO:0070068
name: VAMP4-syntaxin-6-syntaxin-16-Vti1a complex
namespace: cellular_component
def:
  "A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof)." [PMID:11839770]


id: GO:0070069
name: cytochrome complex
namespace: cellular_component
def:
  "A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions." [GOC:mah]


id: GO:0070070
name: proton-transporting V-type ATPase complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient." [GOC:mah]


id: GO:0070071
name: proton-transporting two-sector ATPase complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane." [GOC:mah]


id: GO:0070072
name: vacuolar proton-transporting V-type ATPase complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane." [GOC:BHF, GOC:mah]


id: GO:0070073
name: clustering of voltage-gated calcium channels
namespace: biological_process
def:
  "The process in which voltage-gated calcium channels become localized together in high densities." [GOC:BHF, GOC:sart, PMID:18385325]


id: GO:0070074
name: mononeme
namespace: cellular_component
def:
  "A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts." [GOC:BHF, PMID:18048320]


id: GO:0070075
name: tear secretion
namespace: biological_process
def:
  "The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium." [GOC:rph]


id: GO:0070077
name: histone arginine demethylation
namespace: biological_process
def:
  "The modification of a histone by the removal of a methyl group from an arginine residue." [GOC:mah]


id: GO:0070078
name: histone H3-R2 demethylation
namespace: biological_process
def:
  "The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone." [GOC:BHF, GOC:vk]


id: GO:0070079
name: histone H4-R3 demethylation
namespace: biological_process
def:
  "The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone." [GOC:BHF, GOC:vk]


id: GO:0070080
name: titin Z domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34." [GOC:mah, InterPro:IPR015129]


id: GO:0070081
name: clathrin-sculpted monoamine transport vesicle
namespace: cellular_component
def:
  "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines." [GOC:mg2]


id: GO:0070082
name: clathrin-sculpted monoamine transport vesicle lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle." [GOC:mg2]


id: GO:0070084
name: protein initiator methionine removal
namespace: biological_process
def:
  "The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein." [GOC:imk, GOC:mah]


id: GO:0070085
name: glycosylation
namespace: biological_process
def:
  "The covalent attachment and further modification of carbohydrate residues to a substrate molecule." [GOC:hjd, GOC:mah]


id: GO:0070086
name: ubiquitin-dependent endocytosis
namespace: biological_process
def:
  "Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded." [GOC:jp, GOC:mah, PMID:9409540]


id: GO:0070087
name: chromo shadow domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain." [GOC:BHF, GOC:vk, InterPro:IPR008251, PMID:7667093]


id: GO:0070088
name: PHA granule
namespace: cellular_component
def:
  "An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR." [GOC:mah, PMID:15762612]


id: GO:0070089
name: chloride-activated potassium channel activity
namespace: molecular_function
def:
  "Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient." [GOC:kmv, GOC:mtg_transport]


id: GO:0070090
name: metaphase plate
namespace: cellular_component
def:
  "The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division." [GOC:mah]


id: GO:0070091
name: glucagon secretion
namespace: biological_process
def:
  "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl]


id: GO:0070092
name: regulation of glucagon secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]


id: GO:0070093
name: negative regulation of glucagon secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]


id: GO:0070094
name: positive regulation of glucagon secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]


id: GO:0070096
name: mitochondrial outer membrane translocase complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex." [GOC:BHF, GOC:vk]


id: GO:0070097
name: delta-catenin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the delta subunit of the catenin complex." [GOC:rph]


id: GO:0070098
name: chemokine-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling]


id: GO:0070099
name: regulation of chemokine-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah]


id: GO:0070100
name: negative regulation of chemokine-mediated signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah]


id: GO:0070101
name: positive regulation of chemokine-mediated signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah]


id: GO:0070102
name: interleukin-6-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:add, GOC:BHF, GOC:mah, GOC:signaling]


id: GO:0070103
name: regulation of interleukin-6-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070104
name: negative regulation of interleukin-6-mediated signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070105
name: positive regulation of interleukin-6-mediated signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070106
name: interleukin-27-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:add, GOC:BHF, GOC:mah, GOC:signaling]


id: GO:0070107
name: regulation of interleukin-27-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070108
name: negative regulation of interleukin-27-mediated signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070109
name: positive regulation of interleukin-27-mediated signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor." [GOC:BHF, GOC:mah]


id: GO:0070110
name: ciliary neurotrophic factor receptor complex
namespace: cellular_component
def:
  "A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR." [GOC:BHF, GOC:mah, GOC:rl, PMID:12707266]


id: GO:0070111
name: organellar chromatophore
namespace: cellular_component
def:
  "A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora." [GOC:expert_mm, PMID:18356055]


id: GO:0070113
name: organellar chromatophore inner membrane
namespace: cellular_component
def:
  "The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore." [GOC:mah]


id: GO:0070114
name: organellar chromatophore outer membrane
namespace: cellular_component
def:
  "The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore." [GOC:mah]


id: GO:0070115
name: organellar chromatophore intermembrane space
namespace: cellular_component
def:
  "The region between the inner and outer lipid bilayers that surround an organellar chromatophore." [GOC:mah]


id: GO:0070119
name: ciliary neurotrophic factor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor." [GOC:BHF, GOC:mah]


id: GO:0070120
name: ciliary neurotrophic factor-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mah]


id: GO:0070121
name: Kupffer's vesicle development
namespace: biological_process
def:
  "The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period." [GOC:dgh]


id: GO:0070122
name: isopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond)." [GOC:mah, http://128.240.24.212/cgi-bin/omd?isopeptide+bond]


id: GO:0070123
name: transforming growth factor beta receptor activity, type III
namespace: molecular_function
def:
  "Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors." [GOC:BHF, GOC:mah, PMID:9759503]


id: GO:0070124
name: mitochondrial translational initiation
namespace: biological_process
def:
  "The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA." [GOC:mah]


id: GO:0070125
name: mitochondrial translational elongation
namespace: biological_process
def:
  "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." [GOC:mah]


id: GO:0070126
name: mitochondrial translational termination
namespace: biological_process
def:
  "The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)." [GOC:mah, http://mitogenome.org/index.php/Genetic_Code_of_mitochondria]


id: GO:0070127
name: tRNA aminoacylation for mitochondrial protein translation
namespace: biological_process
def:
  "The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion." [GOC:mah]


id: GO:0070129
name: regulation of mitochondrial translation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah]


id: GO:0070130
name: negative regulation of mitochondrial translation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah]


id: GO:0070131
name: positive regulation of mitochondrial translation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah]


id: GO:0070132
name: regulation of mitochondrial translational initiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah]


id: GO:0070133
name: negative regulation of mitochondrial translational initiation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah]


id: GO:0070134
name: positive regulation of mitochondrial translational initiation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah]


id: GO:0070135
name: beta-1,2-oligomannoside metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan." [GOC:mah, PMID:18234669]


id: GO:0070136
name: beta-1,2-oligomannoside biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan." [GOC:mah, PMID:18234669]


id: GO:0070137
name: ubiquitin-like protein-specific endopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO)." [GOC:mah]


id: GO:0070138
name: ubiquitin-like protein-specific isopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated." [GOC:mah]


id: GO:0070139
name: SUMO-specific endopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO." [GOC:mah]


id: GO:0070140
name: SUMO-specific isopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated." [GOC:mah]


id: GO:0070141
name: response to UV-A
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm." [GOC:BHF, GOC:mah]


id: GO:0070143
name: mitochondrial alanyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070144
name: mitochondrial arginyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070145
name: mitochondrial asparaginyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070146
name: mitochondrial aspartyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070147
name: mitochondrial cysteinyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070148
name: mitochondrial glutaminyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070149
name: mitochondrial glutamyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070150
name: mitochondrial glycyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070151
name: mitochondrial histidyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070152
name: mitochondrial isoleucyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070153
name: mitochondrial leucyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070154
name: mitochondrial lysyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070155
name: mitochondrial methionyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070156
name: mitochondrial phenylalanyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070157
name: mitochondrial prolyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070158
name: mitochondrial seryl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070159
name: mitochondrial threonyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070160
name: occluding junction
namespace: cellular_component
def:
  "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." [ISBN:0815332181]


id: GO:0070161
name: anchoring junction
namespace: cellular_component
def:
  "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181]


id: GO:0070163
name: regulation of adiponectin secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:mah]


id: GO:0070164
name: negative regulation of adiponectin secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:BHF, GOC:mah]


id: GO:0070165
name: positive regulation of adiponectin secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:BHF, GOC:mah]


id: GO:0070166
name: enamel mineralization
namespace: biological_process
def:
  "The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel." [GOC:BHF, GOC:mah, GOC:sl, PMID:10206335, PMID:16931858, PMID:21196346]


id: GO:0070167
name: regulation of biomineral tissue development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah]


id: GO:0070168
name: negative regulation of biomineral tissue development
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah]


id: GO:0070169
name: positive regulation of biomineral tissue development
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah]


id: GO:0070170
name: regulation of tooth mineralization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah]


id: GO:0070171
name: negative regulation of tooth mineralization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah]


id: GO:0070172
name: positive regulation of tooth mineralization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah]


id: GO:0070173
name: regulation of enamel mineralization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah]


id: GO:0070174
name: negative regulation of enamel mineralization
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah]


id: GO:0070175
name: positive regulation of enamel mineralization
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah]


id: GO:0070176
name: DRM complex
namespace: cellular_component
def:
  "A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification." [PMID:17075059]


id: GO:0070177
name: contractile vacuole discharge
namespace: biological_process
def:
  "The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane." [GOC:mah, PMID:10369671]


id: GO:0070178
name: D-serine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid." [CHEBI:16523, GOC:jsg, GOC:mah]


id: GO:0070179
name: D-serine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine." [CHEBI:16523, GOC:jsg, GOC:mah]


id: GO:0070180
name: large ribosomal subunit rRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA." [GOC:elh]


id: GO:0070181
name: small ribosomal subunit rRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA." [GOC:elh]


id: GO:0070183
name: mitochondrial tryptophanyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070184
name: mitochondrial tyrosyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling threonine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070185
name: mitochondrial valyl-tRNA aminoacylation
namespace: biological_process
def:
  "The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc]


id: GO:0070186
name: growth hormone activity
namespace: molecular_function
def:
  "The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth." [GOC:BHF, GOC:mah, PMID:11445442]


id: GO:0070187
name: telosome
namespace: cellular_component
def:
  "A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex contains TRF1, TRF2, POT1, RAP1, TIN2 and TPP1 in mammalian cells, and Pot1, Tpz1, Ccq1, Poz1, Rap1, Rif1, Rif2and Rap1 in Schizosaccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1." [GOC:expert_mf, GOC:mah, GOC:vw, PMID:18828880]


id: GO:0070188
name: obsolete Stn1-Ten1 complex
namespace: cellular_component
def:
  "OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present." [GOC:mah, GOC:vw, PMID:17715303, PMID:19064932]


id: GO:0070189
name: kynurenine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine." [CHEBI:28683, GOC:mah, GOC:rph]


id: GO:0070190
name: obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179]


id: GO:0070191
name: methionine-R-sulfoxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin." [GOC:mcc, PMID:17535911, PMID:19049972]


id: GO:0070193
name: synaptonemal complex organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis." [GOC:mah]


id: GO:0070195
name: growth hormone receptor complex
namespace: cellular_component
def:
  "A receptor complex that consists of two identical subunits and binds growth hormone." [GOC:BHF, GOC:mah, GOC:vk, PMID:11445442]


id: GO:0070196
name: eukaryotic translation initiation factor 3 complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex." [GOC:mah]


id: GO:0070197
name: meiotic attachment of telomere to nuclear envelope
namespace: biological_process
def:
  "The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation." [GOC:jp, GOC:pr, GOC:vw, PMID:18818742]


id: GO:0070198
name: protein localization to chromosome, telomeric region
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome." [GOC:BHF, GOC:mah]


id: GO:0070200
name: establishment of protein localization to telomere
namespace: biological_process
def:
  "The directed movement of a protein to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:mah]


id: GO:0070201
name: regulation of establishment of protein localization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah]


id: GO:0070202
name: regulation of establishment of protein localization to chromosome
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah]


id: GO:0070203
name: regulation of establishment of protein localization to telomere
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:mah]


id: GO:0070204
name: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2)." [EC:2.2.1.9, RHEA:25596]


id: GO:0070205
name: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate." [EC:4.2.99.20, RHEA:25600]


id: GO:0070206
name: protein trimerization
namespace: biological_process
def:
  "The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits." [GOC:hjd]


id: GO:0070207
name: protein homotrimerization
namespace: biological_process
def:
  "The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits." [GOC:hjd]


id: GO:0070208
name: protein heterotrimerization
namespace: biological_process
def:
  "The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical." [GOC:hjd]


id: GO:0070209
name: ASTRA complex
namespace: cellular_component
def:
  "A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p." [GOC:rb, PMID:19040720]


id: GO:0070210
name: Rpd3L-Expanded complex
namespace: cellular_component
def:
  "A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins." [GOC:rb, PMID:19040720]


id: GO:0070211
name: Snt2C complex
namespace: cellular_component
def:
  "A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p." [GOC:rb, PMID:19040720]


id: GO:0070212
name: protein poly-ADP-ribosylation
namespace: biological_process
def:
  "The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain." [GOC:BHF, GOC:mah, GOC:rl]


id: GO:0070213
name: protein auto-ADP-ribosylation
namespace: biological_process
def:
  "The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GOC:BHF, GOC:rl]


id: GO:0070214
name: CSK-GAP-A.p62 complex
namespace: cellular_component
def:
  "A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation." [PMID:7544435]


id: GO:0070215
name: obsolete MDM2 binding
namespace: molecular_function
def:
  "OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM2 protein, a negative regulator of p53." [GOC:mah, GOC:nln]


id: GO:0070216
name: obsolete MDM4 binding
namespace: molecular_function
def:
  "OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM4 protein, a negative regulator of p53." [GOC:mah, GOC:nln]


id: GO:0070217
name: transcription factor TFIIIB complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex." [GOC:mah]


id: GO:0070218
name: sulfide ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell." [GOC:mah]


id: GO:0070219
name: cellular sulfide ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell." [GOC:mah]


id: GO:0070220
name: aerobic sulfur oxidation
namespace: biological_process
def:
  "A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen." [MetaCyc:SULFUROX-PWY]


id: GO:0070221
name: sulfide oxidation, using sulfide:quinone oxidoreductase
namespace: biological_process
def:
  "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase." [MetaCyc:P222-PWY]


id: GO:0070222
name: sulfide oxidation, using sulfide dehydrogenase
namespace: biological_process
def:
  "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase." [MetaCyc:PWY-5274]


id: GO:0070223
name: sulfide oxidation, using sulfur dioxygenase
namespace: biological_process
def:
  "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase." [MetaCyc:PWY-5285]


id: GO:0070225
name: sulfide dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c." [MetaCyc:RXN-8156]


id: GO:0070226
name: sulfur:ferric ion oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+." [MetaCyc:SULFFEOXIDO-RXN]


id: GO:0070227
name: lymphocyte apoptotic process
namespace: biological_process
def:
  "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070228
name: regulation of lymphocyte apoptotic process
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070229
name: negative regulation of lymphocyte apoptotic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070230
name: positive regulation of lymphocyte apoptotic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070231
name: T cell apoptotic process
namespace: biological_process
def:
  "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070232
name: regulation of T cell apoptotic process
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070233
name: negative regulation of T cell apoptotic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070234
name: positive regulation of T cell apoptotic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070235
name: regulation of activation-induced cell death of T cells
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196]


id: GO:0070236
name: negative regulation of activation-induced cell death of T cells
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196]


id: GO:0070237
name: positive regulation of activation-induced cell death of T cells
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196]


id: GO:0070238
name: activated T cell autonomous cell death
namespace: biological_process
def:
  "A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070239
name: regulation of activated T cell autonomous cell death
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070240
name: negative regulation of activated T cell autonomous cell death
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070241
name: positive regulation of activated T cell autonomous cell death
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070242
name: thymocyte apoptotic process
namespace: biological_process
def:
  "Any apoptotic process in a thymocyte, an immature T cell located in the thymus." [CL:0000893, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070243
name: regulation of thymocyte apoptotic process
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070244
name: negative regulation of thymocyte apoptotic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070245
name: positive regulation of thymocyte apoptotic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070246
name: natural killer cell apoptotic process
namespace: biological_process
def:
  "Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation." [CL:0000623, GOC:add, GOC:mtg_apoptosis, PMID:15728472]


id: GO:0070247
name: regulation of natural killer cell apoptotic process
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070248
name: negative regulation of natural killer cell apoptotic process
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070249
name: positive regulation of natural killer cell apoptotic process
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


id: GO:0070250
name: mating projection membrane
namespace: cellular_component
def:
  "The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone." [GOC:jp]


id: GO:0070251
name: pristanate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA." [GOC:pde, PMID:10198260]


id: GO:0070252
name: actin-mediated cell contraction
namespace: biological_process
def:
  "The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body." [GOC:mah]


id: GO:0070253
name: somatostatin secretion
namespace: biological_process
def:
  "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah]


id: GO:0070254
name: mucus secretion
namespace: biological_process
def:
  "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544]


id: GO:0070255
name: regulation of mucus secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]


id: GO:0070256
name: negative regulation of mucus secretion
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]


id: GO:0070257
name: positive regulation of mucus secretion
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]


id: GO:0070258
name: inner membrane complex
namespace: cellular_component
def:
  "A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell." [GOC:mah, PMID:12456714]


id: GO:0070259
name: tyrosyl-DNA phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA." [GOC:elh, PMID:16751265]


id: GO:0070260
name: 5'-tyrosyl-DNA phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA." [PMID:16751265]


id: GO:0070262
name: peptidyl-serine dephosphorylation
namespace: biological_process
def:
  "The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine." [GOC:bf]


id: GO:0070263
name: external side of fungal-type cell wall
namespace: cellular_component
def:
  "The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents." [GOC:mah]


id: GO:0070264
name: transcription factor TFIIIE complex
namespace: cellular_component
def:
  "A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins." [GOC:jp, PMID:19116144]


id: GO:0070265
name: necrotic cell death
namespace: biological_process
def:
  "A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." [GOC:mtg_apoptosis, PMID:18846107, PMID:20823910]


id: GO:0070266
name: necroptotic process
namespace: biological_process
def:
  "A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former." [GOC:BHF, GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, PMID:18846107, PMID:20823910, PMID:21737330, PMID:21760595, PMID:21876153]


id: GO:0070267
name: oncosis
namespace: biological_process
def:
  "A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death." [PMID:17873035, PMID:18846107]


id: GO:0070268
name: cornification
namespace: biological_process
def:
  "A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability)." [GOC:krc, PMID:18846107]


id: GO:0070269
name: pyroptosis
namespace: biological_process
def:
  "A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18." [GOC:mtg_apoptosis, PMID:18846107, PMID:21760595]


id: GO:0070270
name: obsolete mitotic catastrophe
namespace: biological_process
def:
  "OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation." [PMID:18846107]


id: GO:0070271
name: protein complex biogenesis
namespace: biological_process
def:
  "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex." [GOC:mah]


id: GO:0070272
name: proton-transporting ATP synthase complex biogenesis
namespace: biological_process
def:
  "The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:mah, PMID:19103153]


id: GO:0070273
name: phosphatidylinositol-4-phosphate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position." [GOC:bf, GOC:mah]


id: GO:0070274
name: RES complex
namespace: cellular_component
def:
  "A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p." [PMID:15565172, PMID:18809678, PMID:19010333, PMID:19033360]


id: GO:0070275
name: aerobic ammonia oxidation to nitrite via pyruvic oxime
namespace: biological_process
def:
  "The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite." [MetaCyc:PWY-2242]


id: GO:0070276
name: halogen metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds." [CHEBI:22473, GOC:mah]


id: GO:0070277
name: iodide oxidation
namespace: biological_process
def:
  "The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons." [GOC:mah, MetaCyc:IODIDE-PEROXIDASE-RXN]


id: GO:0070278
name: extracellular matrix constituent secretion
namespace: biological_process
def:
  "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell." [GOC:mah]


id: GO:0070279
name: vitamin B6 binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:mah]


id: GO:0070280
name: pyridoxal binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6." [CHEBI:17310, GOC:mah]


id: GO:0070281
name: pyridoxamine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6." [CHEBI:16410, GOC:mah]


id: GO:0070282
name: pyridoxine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6." [CHEBI:16709, GOC:mah]


id: GO:0070283
name: radical SAM enzyme activity
namespace: molecular_function
def:
  "Catalysis of a reaction in which S-adenosyl-L-methionine (SAM) undergoes reductive cleavage to serve as a source of the 5'-deoxyadenosyl radical." [PMID:17291766, PMID:18307109]


id: GO:0070284
name: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine." [PMID:18953358]


id: GO:0070285
name: pigment cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs]


id: GO:0070286
name: axonemal dynein complex assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion." [GOC:mah, PMID:19052621]


id: GO:0070287
name: ferritin receptor activity
namespace: molecular_function
def:
  "Combining with ferritin, and delivering ferritin into the cell via endocytosis." [GOC:bf, PMID:17459943, PMID:19154717]


id: GO:0070288
name: ferritin complex
namespace: cellular_component
def:
  "A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain." [GOC:mah, PMID:19154717]


id: GO:0070289
name: extracellular ferritin complex
namespace: cellular_component
def:
  "A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains." [GOC:mah, PMID:19154717]


id: GO:0070290
name: N-acylphosphatidylethanolamine-specific phospholipase D activity
namespace: molecular_function
def:
  "Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE)." [GOC:elh, PMID:14634025, PMID:15878693]


id: GO:0070291
name: N-acylethanolamine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group." [CHEBI:52640, GOC:elh, PMID:14634025, PMID:15878693]


id: GO:0070292
name: N-acylphosphatidylethanolamine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group." [GOC:elh, GOC:mah, PMID:14634025, PMID:15878693]


id: GO:0070293
name: renal absorption
namespace: biological_process
def:
  "A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)." [GOC:dph, GOC:mah, GOC:yaf]


id: GO:0070294
name: renal sodium ion absorption
namespace: biological_process
def:
  "A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:dph, GOC:mah]


id: GO:0070295
name: renal water absorption
namespace: biological_process
def:
  "A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:dph, GOC:mah]


id: GO:0070296
name: sarcoplasmic reticulum calcium ion transport
namespace: biological_process
def:
  "The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum." [GOC:BHF, GOC:vk]


id: GO:0070297
name: regulation of phosphorelay signal transduction system
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah]


id: GO:0070298
name: negative regulation of phosphorelay signal transduction system
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah]


id: GO:0070299
name: positive regulation of phosphorelay signal transduction system
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah]


id: GO:0070300
name: phosphatidic acid binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids." [CHEBI:16337, GOC:jp, ISBN:0198506732]


id: GO:0070301
name: cellular response to hydrogen peroxide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus." [CHEBI:16240, GOC:mah]


id: GO:0070302
name: regulation of stress-activated protein kinase signaling cascade
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade." [GOC:mah]


id: GO:0070303
name: negative regulation of stress-activated protein kinase signaling cascade
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade." [GOC:mah]


id: GO:0070304
name: positive regulation of stress-activated protein kinase signaling cascade
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade." [GOC:mah]


id: GO:0070305
name: response to cGMP
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus." [GOC:sl]


id: GO:0070306
name: lens fiber cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities." [GOC:mah, PMID:7693735]


id: GO:0070307
name: lens fiber cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735]


id: GO:0070308
name: lens fiber cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735]


id: GO:0070309
name: lens fiber cell morphogenesis
namespace: biological_process
def:
  "The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735]


id: GO:0070310
name: ATR-ATRIP complex
namespace: cellular_component
def:
  "A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A." [GOC:mah, PMID:14724280]


id: GO:0070311
name: nucleosomal methylation activator complex
namespace: cellular_component
def:
  "A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription." [GOC:mah, PMID:14729568]


id: GO:0070312
name: RAD52-ERCC4-ERCC1 complex
namespace: cellular_component
def:
  "A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein." [PMID:14734547]


id: GO:0070313
name: RGS6-DNMT1-DMAP1 complex
namespace: cellular_component
def:
  "A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1." [GOC:mah, PMID:14734556]


id: GO:0070314
name: G1 to G0 transition
namespace: biological_process
def:
  "A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence." [GOC:mah, GOC:mtg_cell_cycle, ISBN:0815316194]


id: GO:0070315
name: G1 to G0 transition involved in cell differentiation
namespace: biological_process
def:
  "A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation." [GOC:mah, ISBN:0815316194]


id: GO:0070316
name: regulation of G0 to G1 transition
namespace: biological_process
def:
  "A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah]


id: GO:0070317
name: negative regulation of G0 to G1 transition
namespace: biological_process
def:
  "A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah]


id: GO:0070318
name: positive regulation of G0 to G1 transition
namespace: biological_process
def:
  "A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah]


id: GO:0070319
name: Golgi to plasma membrane transport vesicle
namespace: cellular_component
def:
  "A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah]


id: GO:0070321
name: regulation of translation in response to nitrogen starvation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah]


id: GO:0070322
name: negative regulation of translation in response to nitrogen starvation
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah]


id: GO:0070323
name: positive regulation of translation in response to nitrogen starvation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah]


id: GO:0070324
name: thyroid hormone binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland." [GOC:rph]


id: GO:0070325
name: lipoprotein particle receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a lipoprotein particle receptor." [GOC:BHF, GOC:rl]


id: GO:0070326
name: very-low-density lipoprotein particle receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a very-low-density lipoprotein receptor." [GOC:BHF, GOC:mah]


id: GO:0070327
name: thyroid hormone transport
namespace: biological_process
def:
  "The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:rph]


id: GO:0070328
name: triglyceride homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell." [GOC:BHF, GOC:mah]


id: GO:0070329
name: tRNA seleno-modification
namespace: biological_process
def:
  "The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule." [GOC:jsg, PMID:14594807]


id: GO:0070331
name: CD20-Lck-Fyn complex
namespace: cellular_component
def:
  "A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn." [GOC:mah, PMID:7545683]


id: GO:0070332
name: CD20-Lck-Lyn-Fyn complex
namespace: cellular_component
def:
  "A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn." [GOC:mah, PMID:7545683]


id: GO:0070333
name: alpha6-beta4 integrin-Shc-Grb2 complex
namespace: cellular_component
def:
  "A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2." [PMID:7556090]


id: GO:0070334
name: alpha6-beta4 integrin-laminin 5 complex
namespace: cellular_component
def:
  "A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5." [GOC:mah, PMID:7556090]


id: GO:0070335
name: aspartate binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4." [CHEBI:29995, GOC:mah]


id: GO:0070336
name: flap-structured DNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule." [GOC:mah, PMID:15189154]


id: GO:0070337
name: 3'-flap-structured DNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule." [GOC:mah, PMID:15189154]


id: GO:0070338
name: 5'-flap-structured DNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers." [GOC:mah, PMID:15189154]


id: GO:0070339
name: response to bacterial lipopeptide
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus." [GOC:add, PMID:12077222]


id: GO:0070340
name: detection of bacterial lipopeptide
namespace: biological_process
def:
  "The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal." [GOC:add, PMID:12077222]


id: GO:0070341
name: fat cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl]


id: GO:0070342
name: brown fat cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species." [CL:0000449, GOC:mah, GOC:sl]


id: GO:0070343
name: white fat cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population." [CL:0000448, GOC:mah, GOC:sl]


id: GO:0070344
name: regulation of fat cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070345
name: negative regulation of fat cell proliferation
namespace: biological_process
def:
  "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070346
name: positive regulation of fat cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070347
name: regulation of brown fat cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070348
name: negative regulation of brown fat cell proliferation
namespace: biological_process
def:
  "Any process that stops or decreases the rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070349
name: positive regulation of brown fat cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070350
name: regulation of white fat cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070351
name: negative regulation of white fat cell proliferation
namespace: biological_process
def:
  "Any process that stops or decreases the rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070352
name: positive regulation of white fat cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl]


id: GO:0070353
name: GATA1-TAL1-TCF3-Lmo2 complex
namespace: cellular_component
def:
  "A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis." [PMID:7568177]


id: GO:0070354
name: GATA2-TAL1-TCF3-Lmo2 complex
namespace: cellular_component
def:
  "A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis." [PMID:7568177]


id: GO:0070355
name: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof)." [PMID:7654227]


id: GO:0070356
name: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex
namespace: cellular_component
def:
  "A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof)." [PMID:7654227]


id: GO:0070357
name: alphav-beta3 integrin-CD47 complex
namespace: cellular_component
def:
  "A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP)." [PMID:2277087, PMID:7691831]


id: GO:0070358
name: actin polymerization-dependent cell motility
namespace: biological_process
def:
  "A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell." [GOC:mah, PMID:15773977]


id: GO:0070359
name: actin polymerization-dependent cell motility involved in migration of symbiont in host
namespace: biological_process
def:
  "A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell." [GOC:jl, GOC:mah, PMID:15773977]


id: GO:0070360
name: migration of symbiont within host by polymerization of host actin
namespace: biological_process
def:
  "The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:mah]


id: GO:0070361
name: mitochondrial light strand promoter anti-sense binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the anti-sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA." [GOC:mah, PMID:9485316]


id: GO:0070362
name: mitochondrial heavy strand promoter anti-sense binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA." [GOC:mah, PMID:9485316]


id: GO:0070363
name: mitochondrial light strand promoter sense binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA." [GOC:mah, PMID:9485316]


id: GO:0070364
name: mitochondrial heavy strand promoter sense binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA." [GOC:mah, PMID:9485316]


id: GO:0070365
name: hepatocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884]


id: GO:0070366
name: regulation of hepatocyte differentiation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]


id: GO:0070367
name: negative regulation of hepatocyte differentiation
namespace: biological_process
def:
  "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]


id: GO:0070368
name: positive regulation of hepatocyte differentiation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]


id: GO:0070369
name: beta-catenin-TCF7L2 complex
namespace: cellular_component
def:
  "A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:rl, PMID:9065401, PMID:9065402]


id: GO:0070371
name: ERK1 and ERK2 cascade
namespace: biological_process
def:
  "An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0121245462, ISBN:0896039986, PMID:20811974]


id: GO:0070372
name: regulation of ERK1 and ERK2 cascade
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986]


id: GO:0070373
name: negative regulation of ERK1 and ERK2 cascade
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986]


id: GO:0070374
name: positive regulation of ERK1 and ERK2 cascade
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:mah]


id: GO:0070375
name: ERK5 cascade
namespace: biological_process
def:
  "An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0896039986, PMID:16376520, PMID:16880823, PMID:20811974]


id: GO:0070376
name: regulation of ERK5 cascade
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986]


id: GO:0070377
name: negative regulation of ERK5 cascade
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986]


id: GO:0070378
name: positive regulation of ERK5 cascade
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:mah]


id: GO:0070379
name: high mobility group box 1 binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1)." [GOC:add, PMID:18431461]


id: GO:0070380
name: high mobility group box 1 receptor activity
namespace: molecular_function
def:
  "Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, PMID:18431461]


id: GO:0070381
name: endosome to plasma membrane transport vesicle
namespace: cellular_component
def:
  "A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane  and to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah, PMID:10679016, PMID:12110576]


id: GO:0070382
name: exocytic vesicle
namespace: cellular_component
def:
  "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah]


id: GO:0070384
name: Harderian gland development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species." [GOC:hjd, PMID:16856596, PMID:7559104]


id: GO:0070385
name: egasyn-beta-glucuronidase complex
namespace: cellular_component
def:
  "A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum." [PMID:7744842]


id: GO:0070386
name: procollagen-proline 4-dioxygenase complex, alpha(I) type
namespace: cellular_component
def:
  "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline)." [PMID:14500733, PMID:7753822]


id: GO:0070387
name: procollagen-proline 4-dioxygenase complex, alpha(II) type
namespace: cellular_component
def:
  "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations." [PMID:14500733, PMID:7753822]


id: GO:0070388
name: procollagen-proline 4-dioxygenase complex, alpha(III) type
namespace: cellular_component
def:
  "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform." [PMID:14500733]


id: GO:0070389
name: chaperone cofactor-dependent protein refolding
namespace: biological_process
def:
  "The process of assisting in the restoration of the biological activity of an unfolded or misfolded protein, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release." [GOC:mah, GOC:rb]


id: GO:0070390
name: transcription export complex 2
namespace: cellular_component
def:
  "A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sus1p and Cdc31p." [GOC:dgf, GOC:mah, PMID:17786152]


id: GO:0070391
name: response to lipoteichoic acid
namespace: biological_process
def:
  "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070392
name: detection of lipoteichoic acid
namespace: biological_process
def:
  "The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070393
name: teichoic acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues." [GOC:add, PMID:14665680]


id: GO:0070394
name: lipoteichoic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070395
name: lipoteichoic acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070396
name: lipoteichoic acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680]


id: GO:0070397
name: wall teichoic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070398
name: wall teichoic acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070399
name: wall teichoic acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680]


id: GO:0070400
name: teichoic acid D-alanylation
namespace: biological_process
def:
  "The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid." [GOC:add, PMID:14665680, PMID:16020688]


id: GO:0070401
name: NADP+ binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah]


id: GO:0070402
name: NADPH binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah]


id: GO:0070403
name: NAD+ binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah]


id: GO:0070404
name: NADH binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah]


id: GO:0070406
name: glutamine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid." [CHEBI:28300, GOC:ecd]


id: GO:0070407
name: oxidation-dependent protein catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein." [GOC:mah]


id: GO:0070408
name: carbamoyl phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [CHEBI:17672, GOC:mah, GOC:rph]


id: GO:0070409
name: carbamoyl phosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [CHEBI:17672, GOC:mah, GOC:rph]


id: GO:0070410
name: co-SMAD binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a common mediator SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992]


id: GO:0070411
name: I-SMAD binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an inhibitory SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992]


id: GO:0070412
name: R-SMAD binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992]


id: GO:0070413
name: trehalose metabolism in response to stress
namespace: biological_process
def:
  "The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress." [GOC:jp, GOC:mah, PMID:9797333]


id: GO:0070414
name: trehalose metabolism in response to heat stress
namespace: biological_process
def:
  "The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:jp, GOC:mah, PMID:9797333]


id: GO:0070415
name: trehalose metabolism in response to cold stress
namespace: biological_process
def:
  "The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:jp, GOC:mah, PMID:9797333]


id: GO:0070416
name: trehalose metabolism in response to water deprivation
namespace: biological_process
def:
  "The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water." [GOC:jp, GOC:mah, PMID:9797333]


id: GO:0070417
name: cellular response to cold
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:jp]


id: GO:0070418
name: DNA-dependent protein kinase complex
namespace: cellular_component
def:
  "A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku." [GOC:mah, PMID:10854421, PMID:12235392]


id: GO:0070419
name: nonhomologous end joining complex
namespace: cellular_component
def:
  "A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends." [GOC:mah, PMID:17072889, PMID:17938628]


id: GO:0070420
name: Ku-DNA ligase complex
namespace: cellular_component
def:
  "A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria." [GOC:mah, PMID:17938628]


id: GO:0070421
name: DNA ligase III-XRCC1 complex
namespace: cellular_component
def:
  "A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair." [PMID:15141024, PMID:7760816]


id: GO:0070422
name: G-protein beta/gamma-Raf-1 complex
namespace: cellular_component
def:
  "A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein." [GOC:mah, PMID:7782277]


id: GO:0070423
name: nucleotide-binding oligomerization domain containing signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein." [GOC:add, PMID:17944960, PMID:18585455]


id: GO:0070424
name: regulation of nucleotide-binding oligomerization domain containing signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add]


id: GO:0070425
name: negative regulation of nucleotide-binding oligomerization domain containing signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add]


id: GO:0070426
name: positive regulation of nucleotide-binding oligomerization domain containing signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add]


id: GO:0070427
name: nucleotide-binding oligomerization domain containing 1 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1)." [GOC:add, PMID:17944960, PMID:18585455]


id: GO:0070428
name: regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add]


id: GO:0070429
name: negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add]


id: GO:0070430
name: positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add]


id: GO:0070431
name: nucleotide-binding oligomerization domain containing 2 signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2)." [GOC:add, PMID:17944960, PMID:18585455]


id: GO:0070432
name: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add]


id: GO:0070433
name: negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add]


id: GO:0070434
name: positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add]


id: GO:0070435
name: Shc-EGFR complex
namespace: cellular_component
def:
  "A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]


id: GO:0070436
name: Grb2-EGFR complex
namespace: cellular_component
def:
  "A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]


id: GO:0070437
name: Grb2-Shc complex
namespace: cellular_component
def:
  "A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]


id: GO:0070438
name: obsolete mTOR-FKBP12-rapamycin complex
namespace: cellular_component
def:
  "OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus)." [GOC:sl, PMID:20005306, PMID:7822316]


id: GO:0070439
name: Mad-Max-mSin3A complex
namespace: cellular_component
def:
  "A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p." [PMID:7889570]


id: GO:0070440
name: Mad-Max-mSin3B complex
namespace: cellular_component
def:
  "A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p." [PMID:7889570]


id: GO:0070441
name: G-protein beta/gamma-Btk complex
namespace: cellular_component
def:
  "A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein." [GOC:mah, PMID:7972043]


