# go

id: GO:0052586
namespace: molecular_function
name:
  oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor

def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound." [GOC:jl]


id: GO:0052587
name: diacetyl reductase ((R)-acetoin forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH." [EC:1.1.1.303, RHEA:22903]


id: GO:0052588
name: diacetyl reductase ((S)-acetoin forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH." [EC:1.1.1.304, RHEA:27289]


id: GO:0052589
name: malate dehydrogenase (menaquinone) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol." [MetaCyc:RXNI-3]


id: GO:0052590
name: sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol." [MetaCyc:RXN0-5258]


id: GO:0052591
name: sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8." [MetaCyc:GLYC3PDEHYDROG-RXN]


id: GO:0052592
name: oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
namespace: molecular_function
def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:ai]


id: GO:0052593
name: tryptamine:oxygen oxidoreductase (deaminating) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+." [MetaCyc:RXN-1401]


id: GO:0052594
name: aminoacetone:oxygen oxidoreductase(deaminating) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+." [MetaCyc:AMACETOXID-RXN]


id: GO:0052595
name: aliphatic-amine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:AMINEOXID-RXN]


id: GO:0052596
name: phenethylamine:oxygen oxidoreductase (deaminating) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:AMINEPHEN-RXN]


id: GO:0052597
name: diamine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide." [MetaCyc:RXN-9599]


id: GO:0052598
name: histamine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-9600]


id: GO:0052599
name: methylputrescine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-8244]


id: GO:0052600
name: propane-1,3-diamine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-6381]


id: GO:0052601
name: (S)-limonene 1,2-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide." [MetaCyc:RXN-9409]


id: GO:0052602
name: 4-chloronitrobenzene nitroreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O." [MetaCyc:RXN-8833]


id: GO:0052603
name: 1-chloro-4-nitrosobenzene nitroreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O." [MetaCyc:RXN-8834]


id: GO:0052604
name: delta-tocopherol cyclase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol." [MetaCyc:RXN-2561, PMID:12213958]


id: GO:0052605
name: gamma-tocopherol cyclase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol." [MetaCyc:RXN-2543, PMID:12213958]


id: GO:0052606
name: chlorophyllide a oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O." [EC:1.13.12.14, MetaCyc:RXN-7676]


id: GO:0052607
name: 7-hydroxy-chlorophyllide a oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O." [EC:1.13.12.14, MetaCyc:RXN-7677]


id: GO:0052608
name: echinenone 3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8214]


id: GO:0052609
name: 4-ketotorulene 3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8218]


id: GO:0052610
name: beta-cryptoxanthin hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8026]


id: GO:0052611
name: beta-carotene 3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8025]


id: GO:0052612
name: adonirubin 3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8187]


id: GO:0052613
name: canthaxanthin 3-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8186]


id: GO:0052614
name: uracil oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate." [MetaCyc:RXN0-6444, PMID:20369853, PMID:20400551]


id: GO:0052615
name: ent-kaurene oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol." [MetaCyc:1.14.13.78-RXN]


id: GO:0052616
name: ent-kaur-16-en-19-ol oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al." [MetaCyc:RXN-5242]


id: GO:0052617
name: ent-kaur-16-en-19-al oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate." [MetaCyc:RXN-7580]


id: GO:0052618
name: coenzyme F420-0:L-glutamate ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate." [MetaCyc:RXN-8080]


id: GO:0052619
name: coenzyme F420-1:gamma-L-glutamate ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate." [MetaCyc:RXN-8081]


id: GO:0052620
name: thymine dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2." [MetaCyc:RXN-8646]


id: GO:0052621
name: diguanylate cyclase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+)." [EC:2.7.7.65, RHEA:24901]


id: GO:0052622
name: ATP dimethylallyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate." [EC:2.5.1.27, MetaCyc:RXN-4303]


id: GO:0052623
name: ADP dimethylallyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate." [EC:2.5.1.27, MetaCyc:RXN-4305]


id: GO:0052624
name: 2-phytyl-1,4-naphthoquinone methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+." [MetaCyc:RXN-6723, MetaCyc:RXN-7569, PMID:14617060]


id: GO:0052625
name: 4-aminobenzoate amino acid synthetase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10884, PMID:19189963]


id: GO:0052626
name: benzoate amino acid synthetase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10886, PMID:19189963]


id: GO:0052627
name: vanillate amino acid synthetase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10885, PMID:19189963]


id: GO:0052628
name: 4-hydroxybenzoate amino acid synthetase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10884, PMID:19189963]


id: GO:0052629
name: phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+." [MetaCyc:RXN-10958, PMID:19901554]


id: GO:0052630
name: UDP-N-acetylgalactosamine diphosphorylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine." [EC:2.7.7.23]


id: GO:0052631
name: sphingolipid delta-8 desaturase activity
namespace: molecular_function
def:
  "Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8)." [PMID:17600137, PMID:9786850]


id: GO:0052633
name: isocitrate hydro-lyase (cis-aconitate-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cis-aconitate + H2O = isocitrate." [EC:4.2.1.3, GOC:pde, GOC:vw, MetaCyc:ACONITATEHYDR-RXN]


id: GO:0052634
name: C-19 gibberellin 2-beta-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons." [EC:1.14.11.13, GOC:kad]


id: GO:0052635
name: C-20 gibberellin 2-beta-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons." [EC:1.14.11.13, GOC:kad]


id: GO:0052636
name: arabinosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)." [GOC:ai]


id: GO:0052637
name: delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol." [GOC:ai, MetaCyc:RXN-8319, PMID:19682287]


id: GO:0052638
name: indole-3-butyrate beta-glucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP." [MetaCyc:RXN-11655]


id: GO:0052639
name: salicylic acid glucosyltransferase (ester-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP." [MetaCyc:RXN-11659]


id: GO:0052640
name: salicylic acid glucosyltransferase (glucoside-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP." [MetaCyc:RXN-11658]


id: GO:0052641
name: benzoic acid glucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP." [MetaCyc:RXN-11660]


id: GO:0052642
name: lysophosphatidic acid phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol." [PMID:20045079, PMID:7966317]


id: GO:0052643
name: chlorophyllide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl." [CHEBI:38206]


id: GO:0052644
name: chlorophyllide a metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a." [CHEBI:16900]


id: GO:0052645
name: F420-0 metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues." [CHEBI:59532]


id: GO:0052646
name: alditol phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group." [CHEBI:22297, ISBN:0198506732]


id: GO:0052647
name: pentitol phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule." [CHEBI:25898, ISBN:0198506732]


id: GO:0052648
name: ribitol phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose." [CHEBI:26554, ISBN:0198506732]


id: GO:0052649
name: coenzyme gamma-F420-2 metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid." [CHEBI:16848]


id: GO:0052650
name: NADP-retinol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+." [RHEA:25036]


id: GO:0052651
name: monoacylglycerol catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified." [http://cancerweb.ncl.ac.uk/]


id: GO:0052652
name: cyclic purine nucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine." [CHEBI:36982]


id: GO:0052653
name: 3',5'-cyclic diguanylic acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine." [CHEBI:593038]


id: GO:0052654
name: L-leucine transaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN]


id: GO:0052655
name: L-valine transaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN]


id: GO:0052656
name: L-isoleucine transaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN]


id: GO:0052657
name: guanine phosphoribosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.8, GOC:curators]


id: GO:0052658
name: inositol-1,4,5-trisphosphate 5-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate." [EC:3.1.3.56, RHEA:19800]


id: GO:0052659
name: inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [EC:3.1.3.56, RHEA:11395]


id: GO:0052660
name: R-lactaldehyde reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+." [RHEA:23875]


id: GO:0052661
name: S-lactaldehyde reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+." [RHEA:15936]


id: GO:0052662
name: zeaxanthin epoxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O." [EC:1.14.13.90]


id: GO:0052663
name: antheraxanthin epoxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: antheraxanthin + NAD(P)H + H+ + O2 = all-trans-violaxanthin + NAD(P)+ + H2O." [MetaCyc:RXN-7979]


id: GO:0052664
name: nitroalkane oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2." [EC:1.7.3.1]


id: GO:0052665
name: tRNA (uracil-2'-O-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil." [EC:2.1.1.34]


id: GO:0052666
name: tRNA (cytosine-2'-O-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine." [EC:2.1.1.34]


id: GO:0052667
name: phosphomethylethanolamine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)." [KEGG:R06868, MetaCyc:RXN-5642, RHEA:25322]


id: GO:0052668
name: farnesol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: farnesol + nucleoside triphosphate = farnesyl monophosphate + nucleoside diphosphate." [GOC:kd, MetaCyc:RXN-11625]


id: GO:0052669
name: CTP:2-trans,-6-trans-farnesol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+." [MetaCyc:RXN-11625]


id: GO:0052670
name: geraniol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate." [GOC:kd]


id: GO:0052671
name: geranylgeraniol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate." [GOC:kd, MetaCyc:RXN-11629]


id: GO:0052672
name: CTP:geranylgeraniol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP." [MetaCyc:RXN-11629]


id: GO:0052673
name: prenol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity." [GOC:ai, GOC:kd]


id: GO:0052674
name: ent-pimara-9(11),15-diene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate." [RHEA:25547]


id: GO:0052675
name: 3-methylbutanol:NADP oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde." [EC:1.1.1.265, KEGG:R05686]


id: GO:0052676
name: 3-methylbutanol:NAD oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde." [EC:1.1.1.265, KEGG:R05685]


id: GO:0052678
name: levopimaradiene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate." [RHEA:25551]


id: GO:0052679
name: terpentetriene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene." [RHEA:25620]


id: GO:0052680
name: epi-isozizaene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate." [RHEA:25995]


id: GO:0052681
name: alpha-bisabolene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate." [RHEA:25439]


id: GO:0052682
name: epi-cedrol synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate." [RHEA:26118]


id: GO:0052683
name: (Z)-gamma-bisabolene synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate." [RHEA:26084]


id: GO:0052685
name: perillic acid:CoA ligase (ADP-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA." [KEGG:R06368]


id: GO:0052686
name: perillic acid:CoA ligase (AMP-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA." [KEGG:R06368]


id: GO:0052687
name: (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [KEGG:R06396]


id: GO:0052688
name: (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [KEGG:R06515]


id: GO:0052690
name: trichloro-p-hydroquinone reductive dehalogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl." [UM-BBD_reactionID:r0031, UM-BBD_reactionID:r0315]


id: GO:0052691
name: UDP-arabinopyranose mutase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose." [EC:5.4.99.30, RHEA:28353]


id: GO:0052693
name: epoxyqueuosine reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant." [PMID:21502530]


id: GO:0052694
name: jasmonoyl-isoleucine-12-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O." [MetaCyc:RXN-12421, PMID:21576464]


id: GO:0052695
name: cellular glucuronidation
namespace: biological_process
def:
  "The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor." [GOC:BHF]


id: GO:0052696
name: flavonoid glucuronidation
namespace: biological_process
def:
  "The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor." [GOC:BHF, PMID:20056724]


id: GO:0052697
name: xenobiotic glucuronidation
namespace: biological_process
def:
  "The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion." [GOC:BHF, PMID:20056724]


id: GO:0052698
name: ergothioneine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [CHEBI:4828, Wikipedia:Ergothioneine]


id: GO:0052699
name: ergothioneine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [CHEBI:4828, Wikipedia:Ergothioneine]


id: GO:0052700
name: ergothioneine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [CHEBI:4828, Wikipedia:Ergothioneine]


id: GO:0052701
name: cellular modified histidine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [CHEBI:24599, GOC:ai]


id: GO:0052702
name: cellular modified histidine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai]


id: GO:0052703
name: cellular modified histidine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [CHEBI:24599, GOC:ai]


id: GO:0052704
name: ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine
namespace: biological_process
def:
  "The pathway resulting in the formation of ergothioneine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). N-alpha,N-alpha,N-alpha-trimethyl-L-histidine is modified by the ligation of gamma-glutamyl-cysteine and oxygen; this intermediate undergoes further modification by the removal of glutamate to produce hercynylcysteine sulfoxide. Finally, a beta-lyase acts on this compound, removing pyruvate, ammonia and oxygen to produce ergothioneine." [DOI:10.1021/ja101721e, EC:2.1.1.44, PMID:4276459, PMID:5484456, Wikipedia:Ergothioneine]


id: GO:0052705
name: methylhistidine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine." [EC:2.1.1.44]


id: GO:0052706
name: histidine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine." [EC:2.1.1.44]


id: GO:0052707
name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine
namespace: biological_process
def:
  "The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)." [EC:2.1.1.44]


id: GO:0052708
name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [CHEBI:15781, KEGG:C05575]


id: GO:0052709
name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [CHEBI:15781, KEGG:C05575]


id: GO:0052710
name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [CHEBI:15781, KEGG:C05575]


id: GO:0052711
name: ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine
namespace: biological_process
def:
  "The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)." [KEGG:R04878]


id: GO:0052712
name: inositol phosphosphingolipid phospholipase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol." [GOC:ai]


id: GO:0052713
name: inositol phosphorylceramide phospholipase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol." [GOC:ai]


id: GO:0052714
name: mannosyl-inositol phosphorylceramide phospholipase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol." [GOC:ai]


id: GO:0052715
name: mannosyl-diinositol phosphorylceramide phospholipase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol." [GOC:ai]


id: GO:0052717
name: tRNA-specific adenosine-34 deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule." [PMID:17875641]


id: GO:0052718
name: tRNA-specific adenosine-34 deaminase complex
namespace: cellular_component
def:
  "A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human." [PMID:17875641]


id: GO:0052719
name: apurinic/apyrimidinic endoribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends." [PMID:19401441]


id: GO:0052720
name: apurinic/apyrimidinic endodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends." [PMID:19401441]


id: GO:0052721
name: regulation of apurinic/apyrimidinic endodeoxyribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends." [PMID:19401441]


id: GO:0052722
name: fatty acid in-chain hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O." [MetaCyc:RXN-12186]


id: GO:0052723
name: inositol hexakisphosphate 1-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179]


id: GO:0052724
name: inositol hexakisphosphate 3-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179]


id: GO:0052725
name: inositol-1,3,4-trisphosphate 6-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134]


id: GO:0052726
name: inositol-1,3,4-trisphosphate 5-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134]


id: GO:0052729
name: dimethylglycine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine." [EC:2.1.1.157]


id: GO:0052730
name: sarcosine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine." [EC:2.1.1.157]


id: GO:0052735
name: tRNA (cytosine-3-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine." [PMID:21518804, PMID:21518805]


id: GO:0052736
name: beta-glucanase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds." [Wikipedia:Beta-glucan]


id: GO:0052737
name: pyruvate dehydrogenase (quinone) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2." [EC:1.2.5.1]


id: GO:0052738
namespace: molecular_function
name:
  oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor

def:
  "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound." [EC:1.2.5]


id: GO:0052739
name: phosphatidylserine 1-acylhydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid." [KEGG:R04034]


id: GO:0052740
name: 1-acyl-2-lysophosphatidylserine acylhydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate." [BRENDA:3.1.1.32]


id: GO:0052741
name: (R)-limonene 6-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+." [EC:1.14.13.80, RHEA:18960]


id: GO:0052742
name: phosphatidylinositol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate." [GOC:ai]


id: GO:0052743
name: inositol tetrakisphosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate." [GOC:ai]


id: GO:0052744
name: phosphatidylinositol monophosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate." [GOC:ai]


id: GO:0052745
name: inositol phosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate." [GOC:ai]


id: GO:0052746
name: inositol phosphorylation
namespace: biological_process
def:
  "The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms." [CHEBI:24848, ISBN:0198506732]


id: GO:0052747
name: sinapyl alcohol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+." [GOC:mengo_curators, MetaCyc:RXN-1125]


id: GO:0052748
name: baicalin beta-D-glucuronidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate." [GOC:mengo_curators, RHEA:28133]


id: GO:0052749
name: glucose-6-phosphate dehydrogenase (coenzyme F420) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420." [EC:1.1.98.2, GOC:mengo_curators, RHEA:27297]


id: GO:0052750
name: reactive-black-5:hydrogen-peroxide oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O." [KEGG:R07612, MetaCyc:RXN-8666]


id: GO:0052752
name: reduced coenzyme F420:heterodisulfide oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH." [GOC:mengo_curators, PMID:9914308]


id: GO:0052753
name: propan-2-ol:coenzyme F420 oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420." [GOC:mengo_curators, PMID:15016352, PMID:1879431, PMID:8706724]


id: GO:0052754
name: GTP:coenzyme F420 guanyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate." [GOC:mengo_curators, MetaCyc:MONOMER-13942, MetaCyc:RXN-9385]


id: GO:0052755
name: reduced coenzyme F420:quinone oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone." [GOC:mengo_curators, PMID:10971593, PMID:8055920]


id: GO:0052756
name: chitobiose phosphorylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units." [GOC:mengo_curators, PMID:15274915, Wikipedia:chitobiose]


id: GO:0052757
name: chondroitin hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]." [GOC:mengo_curators, PMID:18390555]


id: GO:0052758
name: coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, PMID:11995829, UM-BBD_reactionID:r1065]


id: GO:0052759
name: coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, UM-BBD_reactionID:r1066]


id: GO:0052760
name: coenzyme F420-dependent 2,4-dinitrophenol reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, PMID:11995829, UM-BBD_reactionID:r1071]


id: GO:0052761
name: exo-1,4-beta-D-glucosaminidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units." [EC:3.2.1.165, GOC:mengo_curators, MetaCyc:3.2.1.165-RXN]


id: GO:0052762
name: gellan lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha)." [GOC:mengo_curators, MetaCyc:RXN-12269]


id: GO:0052763
name: ulvan lyase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end." [GOC:mengo_curators, PMID:9468631]


id: GO:0052764
name: exo-oligoalginate lyase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends." [GOC:mengo_curators, PMID:20925655]


id: GO:0052765
name: reduced coenzyme F420 oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O." [GOC:mengo_curators, PMID:15340796]


id: GO:0052766
name: mannoside alpha-1,4-mannosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides." [GOC:mengo_curators, PMID:20081828]


id: GO:0052767
name: mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide." [GOC:mengo_curators, PMID:1849817, PMID:2338081]


id: GO:0052768
name: mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide." [GOC:mengo_curators, PMID:1849817, PMID:2338081]


id: GO:0052769
name: beta-6-sulfate-N-acetylglucosaminidase activity
namespace: molecular_function
def:
  "Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative." [GOC:mengo_curators, PMID:15716424]


id: GO:0052770
name: coenzyme F390-A hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420." [GOC:mengo_curators, PMID:8536708, PMID:9352911]


id: GO:0052771
name: coenzyme F390-G hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420." [GOC:mengo_curators, PMID:8536708, PMID:9352911]


id: GO:0052772
name: brefeldin A esterase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone." [GOC:mengo_curators, PMID:10201402, PMID:8106385]


id: GO:0052773
name: diacetylchitobiose deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc)." [GOC:bf, GOC:mengo_curators, MetaCyc:RXN-12543, PMID:15136574, PMID:16232910, PMID:16736587]


id: GO:0052774
name: glucosyl-N-acetylglucosamine glucosaminidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine." [GOC:mengo_curators, PMID:15136574, PMID:16232910, PMID:16736587]


id: GO:0052775
name: endo-1,3-alpha-L-rhamnosidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain." [GOC:mengo_curators, PMID:10439404]


id: GO:0052776
name: diacetylchitobiose catabolic process to glucosamine and acetate
namespace: biological_process
def:
  "The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate." [GOC:bf, GOC:mengo_curators, MetaCyc:PWY-6855, PMID:15136574, PMID:16232910, PMID:16736587]


id: GO:0052777
name: diacetylchitobiose catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products." [CHEBI:28681]


id: GO:0052778
name: diacetylchitobiose metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose." [CHEBI:28681]


id: GO:0052779
name: amino disaccharide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions." [CHEBI:22480]


id: GO:0052780
name: chitobiose metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine." [CHEBI:50674]


id: GO:0052781
name: chitobiose catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine." [CHEBI:50674]


id: GO:0052782
name: amino disaccharide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions." [CHEBI:22480]


id: GO:0052783
name: reuteran metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages." [PMID:15256553, PMID:16000808]


id: GO:0052784
name: reuteran biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages." [GOC:mengo_curators, PMID:15256553, PMID:16000808]


id: GO:0052785
name: cellulose catabolism by endo-processive cellulases
namespace: biological_process
def:
  "The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments." [GOC:mengo_curators, PMID:18035374]


id: GO:0052786
name: alpha-linked polysaccharide catabolism to maltotriose
namespace: biological_process
def:
  "The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose." [GOC:mengo_curators, PMID:7511484, PMID:9406414]


id: GO:0052787
name: alpha-linked polysaccharide catabolism to maltopentaose
namespace: biological_process
def:
  "The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose." [GOC:mengo_curators, PMID:7511484, PMID:9406414]


id: GO:0052788
name: d-4,5 unsaturated beta-glucuronyl hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue." [GOC:mengo_curators, PMID:12729728]


id: GO:0052789
name: mannan 1,3-beta-mannosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose." [EC:3.2.1.78, GOC:mengo_curators]


id: GO:0052790
name: chitooligosaccharide deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions." [GOC:mengo_curators, PMID:8421697, PMID:8986807]


id: GO:0052791
name: 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain." [GOC:mengo_curators, PMID:21247893]


id: GO:0052792
name: endo-xylogalacturonan hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position." [GOC:mengo_curators, PMID:10618200]


id: GO:0052793
name: pectin acetylesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin." [GOC:mengo_curators, PMID:9218776]


id: GO:0052794
name: exo-alpha-(2->3)-sialidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators]


id: GO:0052795
name: exo-alpha-(2->6)-sialidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators]


id: GO:0052796
name: exo-alpha-(2->8)-sialidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators]


id: GO:0052797
name: 4-O-methyl-glucuronoyl methylesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X]." [GOC:mengo_curators, PMID:16876163]


id: GO:0052798
name: beta-galactoside alpha-2,3-sialyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor." [GOC:mengo_curators, PMID:7826016, PMID:8405811]


id: GO:0052799
name: coenzyme F420-dependent bicyclic nitroimidazole catabolic process
namespace: biological_process
def:
  "The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates." [GOC:mengo_curators, PMID:16387854, PMID:19039139]


id: GO:0052800
name: bicyclic nitroimidazole catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole." [PMID:16387854, PMID:19039139]


id: GO:0052801
name: bicyclic nitroimidazole metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring." [PMID:16387854, PMID:19039139]


id: GO:0052802
name: nitroimidazole metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring." [PMID:16387854, PMID:19039139]


id: GO:0052803
name: imidazole-containing compound metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." [CHEBI:24780]


id: GO:0052804
name: nitroimidazole catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring." [PMID:16387854, PMID:19039139]


id: GO:0052805
name: imidazole-containing compound catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." [CHEBI:24780]


id: GO:0052806
name: sulfite reductase (coenzyme F420) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:16048999]


id: GO:0052807
name: aflatoxin reductase (coenzyme F420) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:20807200]


id: GO:0052808
name: reduced coenzyme F420:NADP+ oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:11726492]


id: GO:0052809
name: acharan sulfate lyase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid." [GOC:mengo_curators, PMID:19566715]


id: GO:0052810
name: 1-phosphatidylinositol-5-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+)." [EC:2.7.1.137]


id: GO:0052811
name: 1-phosphatidylinositol-3-phosphate 4-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.150]


id: GO:0052812
name: phosphatidylinositol-3,4-bisphosphate 5-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)." [EC:2.7.1.153]


id: GO:0052813
name: phosphatidylinositol bisphosphate kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate." [GOC:ai]


id: GO:0052814
name: medium-chain-aldehyde dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons." [EC:1.2.1.48]


id: GO:0052815
name: medium-chain acyl-CoA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length." [EC:3.1.2.19]


id: GO:0052816
name: long-chain acyl-CoA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length." [EC:3.1.2.19]


id: GO:0052817
name: very long chain acyl-CoA hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18." [EC:3.1.2.19]


id: GO:0052818
name: heteroglycan 3-alpha-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48, MetaCyc:RXN-7992]


id: GO:0052819
name: heteroglycan 2-alpha-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48, MetaCyc:2.4.1.48-RXN]


id: GO:0052820
name: DNA-1,N6-ethenoadenine N-glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar." [PMID:21960007]


id: GO:0052821
name: DNA-7-methyladenine glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site." [GOC:jl, PMID:16468998]


id: GO:0052822
name: DNA-3-methylguanine glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623]


id: GO:0052823
name: 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+." [RHEA:25049]


id: GO:0052824
name: dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol." [PMID:10336995]


id: GO:0052825
name: inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate." [GOC:ai]


id: GO:0052826
name: inositol hexakisphosphate 2-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate." [EC:3.1.3.62]


id: GO:0052827
name: inositol pentakisphosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate." [GOC:bf]


id: GO:0052828
name: inositol-3,4-bisphosphate 4-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate." [GOC:mah]


id: GO:0052829
name: inositol-1,3,4-trisphosphate 1-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate." [GOC:ai]


id: GO:0052830
name: inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate." [GOC:ai]


id: GO:0052831
name: inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate." [GOC:ai]


id: GO:0052832
name: inositol monophosphate 3-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25]


id: GO:0052833
name: inositol monophosphate 4-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25]


id: GO:0052835
name: inositol-3,4,6-trisphosphate 1-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134]


id: GO:0052836
name: inositol 5-diphosphate pentakisphosphate 5-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate." [PMID:11502751, PMID:18355727]


id: GO:0052837
name: thiazole biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position." [CHEBI:43732, GOC:curators]


id: GO:0052838
name: thiazole metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position." [CHEBI:43732, GOC:curators]


id: GO:0052839
name: inositol diphosphate tetrakisphosphate kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate." [PMID:10827188, PMID:11502751, PMID:18355727]


id: GO:0052840
name: inositol diphosphate tetrakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate." [MetaCyc:RXN-10963, PMID:10827188, PMID:11502751]


id: GO:0052841
name: inositol bisdiphosphate tetrakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate." [MetaCyc:RXN-10965, MetaCyc:RXN-10975, MetaCyc:RXN-10976, PMID:10827188, PMID:11502751]


id: GO:0052842
name: inositol diphosphate pentakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate." [MetaCyc:RXN-10964, MetaCyc:RXN-10977, MetaCyc:RXN-10978, PMID:10827188, PMID:11502751]


id: GO:0052843
name: inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10977, PMID:10827188, PMID:11502751]


id: GO:0052844
name: inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10978, PMID:10827188, PMID:11502751]


id: GO:0052845
name: inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10964, PMID:10827188, PMID:11502751]


id: GO:0052846
name: inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10965, PMID:10827188, PMID:11502751]


id: GO:0052847
name: inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10975, PMID:10827188, PMID:11502751]


id: GO:0052848
name: inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10976, PMID:10827188, PMID:11502751]


id: GO:0052850
name: NADPH-dependent dihydrocurcumin reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+." [MetaCyc:RXN0-6677]


id: GO:0052852
name: very-long-chain-(S)-2-hydroxy-acid oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: very-long-chain (S)-2-hydroxy-acid + O2 = very-long-chain 2-oxo acid + hydrogen peroxide. Very long chain refers to a chain length of greater than 18 carbons." [EC:1.1.3.15]


id: GO:0052853
name: long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons." [EC:1.1.3.15]


id: GO:0052854
name: medium-chain-(S)-2-hydroxy-acid oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: medium-chain-(S)-2-hydroxy-acid + O2 = medium-chain-2-oxo acid + hydrogen peroxide. Medium chain refers to a chain length of between 8 and 12 carbons." [EC:1.1.3.15]


id: GO:0052855
name: ADP-dependent NAD(P)H-hydrate dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate." [EC:4.2.1.93, PMID:21994945]


id: GO:0052858
name: peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine." [GOC:tb]


id: GO:0052860
name: 2'-deoxymugineic-acid 3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2." [EC:1.14.11.25]


id: GO:0052861
name: glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
namespace: molecular_function
def:
  "Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6]


id: GO:0052862
name: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group
namespace: molecular_function
def:
  "Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6]


id: GO:0052863
name: 1-deoxy-D-xylulose 5-phosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [CHEBI:16493, KEGG:C11437, PubChem:13609]


id: GO:0052864
name: 1-deoxy-D-xylulose 5-phosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [CHEBI:16493, KEGG:C11437, PubChem:13609]


id: GO:0052865
name: 1-deoxy-D-xylulose 5-phosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [CHEBI:16493, KEGG:C11437, PubChem:13609]


id: GO:0052866
name: phosphatidylinositol phosphate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate." [GOC:ai]


id: GO:0052867
name: phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate." [EC:3.1.3.-]


id: GO:0052868
name: protein-lysine lysyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine." [PMID:20729861]


id: GO:0052869
name: arachidonic acid omega-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid." [KEGG:R07041]


id: GO:0052870
name: tocopherol omega-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O ." [MetaCyc:RXN-11003]


id: GO:0052871
name: alpha-tocopherol omega-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O ." [MetaCyc:RXN-11003]


id: GO:0052872
name: tocotrienol omega-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O ." [MetaCyc:RXN-11003]


id: GO:0052876
name: methylamine dehydrogenase (amicyanin) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: methylamine + H2O + amicyanin = formaldehyde + ammonia + reduced amicyanin." [KEGG:R00606]


id: GO:0052877
name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor
namespace: molecular_function
def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor." [GOC:ai]


id: GO:0052878
name: linoleate 8R-lipoxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate." [RHEA:25398]


id: GO:0052879
name: 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate." [RHEA:25402]


id: GO:0052880
namespace: molecular_function
name:
  oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor

def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl]


id: GO:0052881
name: 4-hydroxyphenylacetate 3-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O." [RHEA:30598]


id: GO:0052882
namespace: molecular_function
name:
  oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor

def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl]


id: GO:0052884
name: all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate." [RHEA:31778]


id: GO:0052885
name: all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid." [RHEA:31774]


id: GO:0052886
name: 9,9'-dicis-carotene:quinone oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol." [EC:1.3.5.6]


id: GO:0052887
name: 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol." [EC:1.3.5.6]


id: GO:0052888
name: obsolete OBSOLETE:dihydroorotate oxidase (fumarate) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate." [EC:1.3.98.1, RHEA:30062]


id: GO:0052889
name: 9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene
namespace: biological_process
def:
  "The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene." [EC:1.3.5.6, KEGG:R07511]


id: GO:0052890
name: oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
namespace: molecular_function
def:
  "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin." [GOC:jl]


id: GO:0052891
name: aliphatic (S)-hydroxynitrile lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide." [EC:4.1.2.47]


id: GO:0052892
name: aromatic (S)-hydroxynitrile lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide." [EC:4.1.2.47, KEGG:R09359]


id: GO:0052893
name: N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide." [MetaCyc:RXN-10465]


id: GO:0052894
name: norspermine:oxygen oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide." [MetaCyc:RXN-10464]


id: GO:0052895
name: N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide." [MetaCyc:POLYAMINE-OXIDASE-RXN]


id: GO:0052896
name: spermidine oxidase (propane-1,3-diamine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2)." [RHEA:25823]


id: GO:0052897
name: N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)." [RHEA:25975]


id: GO:0052898
name: N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)." [RHEA:25867]


id: GO:0052899
name: N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine." [RHEA:25871]


id: GO:0052900
name: spermine oxidase (propane-1,3-diamine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal." [RHEA:25827]


id: GO:0052901
name: spermine:oxygen oxidoreductase (spermidine-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine." [RHEA:25807]


id: GO:0052902
name: spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine." [RHEA:25811]


id: GO:0052903
name: N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine." [RHEA:25803]


id: GO:0052904
name: N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine." [RHEA:25815]


id: GO:0052905
name: tRNA (guanine(9)-N(1))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.221]


id: GO:0052906
name: tRNA (guanine(37)-N(1))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.228]


id: GO:0052907
name: 23S rRNA (adenine(1618)-N(6))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA." [EC:2.1.1.181]


id: GO:0052908
name: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA." [EC:2.1.1.182]


id: GO:0052909
name: 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA." [EC:2.1.1.183]


id: GO:0052910
name: 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA." [EC:2.1.1.184]


id: GO:0052911
name: 23S rRNA (guanine(745)-N(1))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.187]


id: GO:0052912
name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.188]


id: GO:0052913
name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.171]


id: GO:0052914
name: 16S rRNA (guanine(1207)-N(2))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.172]


id: GO:0052915
name: 23S rRNA (guanine(2445)-N(2))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.173]


id: GO:0052916
name: 23S rRNA (guanine(1835)-N(2))-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.174]


id: GO:0052917
name: dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.260, RHEA:29538]


id: GO:0052918
name: dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.261, RHEA:29542]


id: GO:0052919
name: aliphatic (R)-hydroxynitrile lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide." [EC:4.1.2.46]


id: GO:0052920
name: (2R)-2-hydroxy-2-methylbutanenitrile lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide." [EC:4.1.2.46]


id: GO:0052921
name: acetone-cyanohydrin acetone-lyase (cyanide-forming) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone." [KEGG:R01553, MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN]


id: GO:0052922
name: hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate." [RHEA:27558]


id: GO:0052923
name: all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate." [EC:2.5.1.84, RHEA:27566]


id: GO:0052924
name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate." [EC:2.5.1.85]


id: GO:0052925
name: dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [RHEA:29530]


id: GO:0052926
name: dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.259, RHEA:29534]


id: GO:0052927
name: CTP:tRNA cytidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate." [KEGG:R09383]


id: GO:0052928
name: CTP:3'-cytidine-tRNA cytidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate." [KEGG:R09384]


id: GO:0052929
name: ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate." [KEGG:R09386]


id: GO:0052930
name: methanol ferricytochrome-c oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: methanol + 2 ferricytochrome c = formaldehyde + 2 ferrocytochrome c + 2 H+." [KEGG:R01146]


id: GO:0052931
name: ethanol cytochrome-c oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ethanol + 2 cytochrome c(L) = acetaldehyde + 2 reduced cytochrome c(L) + 2 H+." [KEGG:R09127]


id: GO:0052932
name: 2-chloroethanol cytochrome-c oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c(L) = chloroacetaldehyde + 2 reduced cytochrome c(L)." [KEGG:R09128]


id: GO:0052933
name: alcohol dehydrogenase (cytochrome c(L)) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: primary alcohol + 2 cytochrome c(L) = 2 reduced cytochrome c(L) + an aldehyde + 2 H+." [EC:1.1.2.7]


id: GO:0052934
name: alcohol dehydrogenase (cytochrome c) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: primary alcohol + 2 cytochrome c = 2 reduced cytochrome c + an aldehyde + 2 H+." [EC:1.1.2.8]


id: GO:0052935
name: ethanol:cytochrome c oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ethanol + 2 cytochrome c = 2 reduced cytochrome c + acetaldehyde." [KEGG:R05198]


id: GO:0052936
name: 2-chloroethanol:cytochrome c oxidoreductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c = chloroacetaldehyde + 2 reduced cytochrome c." [KEGG:R05285]


id: GO:0055001
name: muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol]


id: GO:0055002
name: striated muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol]


id: GO:0055003
name: cardiac myofibril assembly
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol]


id: GO:0055004
name: atrial cardiac myofibril assembly
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol]


id: GO:0055005
name: ventricular cardiac myofibril assembly
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol]


id: GO:0055006
name: cardiac cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol]


id: GO:0055007
name: cardiac muscle cell differentiation
namespace: biological_process
def:
  "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart]


id: GO:0055008
name: cardiac muscle tissue morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol]


id: GO:0055009
name: atrial cardiac muscle tissue morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol]


id: GO:0055010
name: ventricular cardiac muscle tissue morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol]


id: GO:0055011
name: atrial cardiac muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ." [GOC:devbiol, GOC:mtg_heart]


id: GO:0055012
name: ventricular cardiac muscle cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ." [GOC:devbiol, GOC:mtg_heart]


id: GO:0055013
name: cardiac muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart]


id: GO:0055014
name: atrial cardiac muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ." [GOC:devbiol]


id: GO:0055015
name: ventricular cardiac muscle cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ." [GOC:devbiol, GOC:mtg_muscle]


id: GO:0055016
name: hypochord development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta." [GOC:devbiol, GOC:lb]


id: GO:0055017
name: cardiac muscle tissue growth
namespace: biological_process
def:
  "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol]


id: GO:0055018
name: regulation of cardiac muscle fiber development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]


id: GO:0055019
name: negative regulation of cardiac muscle fiber development
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]


id: GO:0055020
name: positive regulation of cardiac muscle fiber development
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]


id: GO:0055022
name: negative regulation of cardiac muscle tissue growth
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk]


id: GO:0055023
name: positive regulation of cardiac muscle tissue growth
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk]


id: GO:0055024
name: regulation of cardiac muscle tissue development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]


id: GO:0055025
name: positive regulation of cardiac muscle tissue development
namespace: biological_process
def:
  "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]


id: GO:0055026
name: negative regulation of cardiac muscle tissue development
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]


id: GO:0055028
name: cortical microtubule
namespace: cellular_component
def:
  "Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol." [GOC:mtg_sensu]


id: GO:0055029
name: nuclear DNA-directed RNA polymerase complex
namespace: cellular_component
def:
  "A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity." [GOC:mtg_sensu]


id: GO:0055031
name: gamma-tubulin large complex, equatorial microtubule organizing center
namespace: cellular_component
def:
  "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at equatorial microtubule organizing centers." [GOC:mtg_sensu]


id: GO:0055032
name: gamma-tubulin large complex, spindle pole body
namespace: cellular_component
def:
  "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body." [GOC:mtg_sensu]


id: GO:0055033
name: gamma-tubulin large complex, interphase microtubule organizing center
namespace: cellular_component
def:
  "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at interphase microtubule organizing centers." [GOC:mtg_sensu]


id: GO:0055034
name: Bolwig's organ development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain." [GOC:mtg_sensu]


id: GO:0055037
name: recycling endosome
namespace: cellular_component
def:
  "An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane." [GOC:dph, GOC:jid, GOC:kmv, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101, PMID:21556374, PMID:21562044]


id: GO:0055038
name: recycling endosome membrane
namespace: cellular_component
def:
  "The lipid bilayer surrounding a recycling endosome." [GOC:jid, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101]


id: GO:0055039
name: trichocyst
namespace: cellular_component
def:
  "A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in \"nets\" to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft." [GOC:jid, GOC:rph, http://www.iscid.org/encyclopedia/, PMID:3667715]


id: GO:0055040
name: periplasmic flagellum
namespace: cellular_component
def:
  "Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella." [GOC:jid, GOC:rph, PMID:15175283, PMID:1624463]


id: GO:0055041
name: cyclopentanol dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH." [EC:1.1.1.163, RHEA:11731]


id: GO:0055043
name: 5-oxovalerate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+." [GOC:jid, GOC:mlg]


id: GO:0055044
name: symplast
namespace: cellular_component
def:
  "The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata." [GOC:mtg_sensu]


id: GO:0055046
name: microgametogenesis
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure." [GOC:mtg_plant]


id: GO:0055047
name: generative cell mitosis
namespace: biological_process
def:
  "The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells." [GOC:mtg_plant]


id: GO:0055048
name: anastral spindle assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins." [GOC:expert_rg, GOC:mtg_sensu, GOC:tb, PMID:15034926]


id: GO:0055049
name: astral spindle assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes." [GOC:tb]


id: GO:0055050
name: astral spindle assembly involved in male meiosis
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells." [GOC:tb]


id: GO:0055051
name: ATP-binding cassette (ABC) transporter complex, integrated substrate binding
namespace: cellular_component
def:
  "A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a \"half transporter\". Two \"half-transporters\" come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu]


id: GO:0055052
name: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
namespace: cellular_component
def:
  "A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu]


id: GO:0055053
name: mannose:proton symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+." [GOC:ct]


id: GO:0055054
name: fructose:proton symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+." [GOC:ct]


id: GO:0055055
name: D-glucose:proton symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose." [GOC:ct]


id: GO:0055056
name: D-glucose transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of the membrane to the other." [GOC:jid, GOC:jsg, GOC:mah]


id: GO:0055057
name: neuroblast division
namespace: biological_process
def:
  "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167]


id: GO:0055058
name: symmetric neuroblast division
namespace: biological_process
def:
  "The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells." [GOC:dph]


id: GO:0055059
name: asymmetric neuroblast division
namespace: biological_process
def:
  "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph]


id: GO:0055060
name: asymmetric neuroblast division resulting in ganglion mother cell formation
namespace: biological_process
def:
  "Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell." [GOC:dph]


id: GO:0055061
name: obsolete di-, tri-valent inorganic anion homeostasis
namespace: biological_process
def:
  "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055062
name: phosphate ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell." [GOC:jid, GOC:mah]


id: GO:0055063
name: sulfate ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." [GOC:jid, GOC:mah]


id: GO:0055064
name: chloride ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell." [GOC:jid, GOC:mah]


id: GO:0055065
name: metal ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055066
name: obsolete di-, tri-valent inorganic cation homeostasis
namespace: biological_process
def:
  "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah]


id: GO:0055067
name: monovalent inorganic cation homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055068
name: cobalt ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055069
name: zinc ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055070
name: copper ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055071
name: manganese ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell." [GOC:jid, GOC:mah]


id: GO:0055072
name: iron ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055073
name: cadmium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055074
name: calcium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah]


id: GO:0055075
name: potassium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell." [GOC:jid, GOC:mah]


id: GO:0055076
name: transition metal ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [GOC:jid, GOC:mah, ISBN:0198506732]


id: GO:0055077
name: gap junction hemi-channel activity
namespace: molecular_function
def:
  "A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction." [GOC:dgh]


id: GO:0055078
name: sodium ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055079
name: aluminum ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell." [GOC:jid, GOC:lr, GOC:mah]


id: GO:0055080
name: cation homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of cations within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah]


id: GO:0055081
name: anion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of anions within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah]


id: GO:0055082
name: cellular chemical homeostasis
namespace: biological_process
def:
  "Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell." [GOC:isa_complete, GOC:jid]


id: GO:0055083
name: monovalent inorganic anion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah]


id: GO:0055085
name: transmembrane transport
namespace: biological_process
def:
  "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other" [GOC:dph, GOC:jid]


id: GO:0055086
name: nucleobase-containing small molecule metabolic process
namespace: biological_process
def:
  "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw]


id: GO:0055087
name: Ski complex
namespace: cellular_component
def:
  "A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p." [GOC:mcc, PMID:10744028, PMID:15703439, PMID:16043509, PMID:18042677]


id: GO:0055088
name: lipid homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell." [GOC:BHF, GOC:rl]


id: GO:0055089
name: fatty acid homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell." [GOC:BHF, GOC:rl]


id: GO:0055090
name: acylglycerol homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell." [GOC:BHF, GOC:rl]


id: GO:0055091
name: phospholipid homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell." [GOC:BHF, GOC:rl]


id: GO:0055092
name: sterol homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of an internal steady state of sterol within an organism or cell." [GOC:BHF, GOC:rl]


id: GO:0055093
name: response to hyperoxia
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension." [GOC:kmv]


id: GO:0055094
name: response to lipoprotein particle
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus." [GOC:BHF, GOC:rl]


id: GO:0055095
name: lipoprotein particle mediated signaling
namespace: biological_process
def:
  "A series of molecular signals mediated by the detection of a lipoprotein particle." [GOC:BHF, GOC:rl]


id: GO:0055096
name: low-density lipoprotein particle mediated signaling
namespace: biological_process
def:
  "A series of molecular signals mediated by the detection of low-density lipoprotein particle." [GOC:BHF, GOC:rl, PMID:16013438]


id: GO:0055097
name: high density lipoprotein particle mediated signaling
namespace: biological_process
def:
  "A series of molecular signals mediated by the detection of high density lipoprotein particle." [GOC:BHF, GOC:rl]


id: GO:0055098
name: response to low-density lipoprotein particle
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus." [GOC:BHF, GOC:rl]


id: GO:0055099
name: response to high density lipoprotein particle
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus." [GOC:BHF, GOC:rl]


id: GO:0055100
name: adiponectin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism." [GOC:BHF, GOC:rl, PMID:15210937]


id: GO:0055101
name: obsolete glycerophospholipase inhibitor activity
namespace: molecular_function
def:
  "OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai, GOC:BHF, GOC:rl]


id: GO:0055102
name: lipase inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:BHF, GOC:rl]


id: GO:0055106
name: ubiquitin-protein transferase regulator activity
namespace: molecular_function
def:
  "Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein." [GOC:BHF, GOC:rl]


id: GO:0055107
name: Golgi to secretory granule transport
namespace: biological_process
def:
  "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators]


id: GO:0055108
name: Golgi to transport vesicle transport
namespace: biological_process
def:
  "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid]


id: GO:0055109
name: invagination involved in gastrulation with mouth forming second
namespace: biological_process
def:
  "The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437]


id: GO:0055110
name: involution involved in gastrulation with mouth forming second
namespace: biological_process
def:
  "The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation." [ISBN:0878932437]


id: GO:0055111
name: ingression involved in gastrulation with mouth forming second
namespace: biological_process
def:
  "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437]


id: GO:0055112
name: delamination involved in gastrulation with mouth forming second
namespace: biological_process
def:
  "The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation." [ISBN:0878932437]


id: GO:0055113
name: epiboly involved in gastrulation with mouth forming second
namespace: biological_process
def:
  "The expansion of one cell sheet over other cells involved in deuterostomic gastrulation." [ISBN:0878932437]


id: GO:0055114
name: oxidation-reduction process
namespace: biological_process
def:
  "A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons." [GOC:dhl, GOC:ecd, GOC:jh2, GOC:jid, GOC:mlg, GOC:rph]


id: GO:0055115
name: entry into diapause
namespace: biological_process
def:
  "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." [GOC:ds, GOC:jid, GOC:mah]


id: GO:0055116
name: entry into reproductive diapause
namespace: biological_process
def:
  "The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:ds, GOC:jid, GOC:mah]


id: GO:0055118
name: negative regulation of cardiac muscle contraction
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd]


id: GO:0055120
name: striated muscle dense body
namespace: cellular_component
def:
  "A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere." [GOC:kmv, PMID:17492481]


id: GO:0055121
name: response to high fluence blue light stimulus by blue high-fluence system
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2." [GOC:mtg_far_red]


id: GO:0055122
name: response to very low light intensity stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec." [GOC:mtg_far_red]


id: GO:0055123
name: digestive system development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid]


id: GO:0055125
name: obsolete Nic96 complex
namespace: cellular_component
def:
  "OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p." [GOC:jh, PMID:12791264, PMID:15741174]


id: GO:0055126
name: obsolete Nup82 complex
namespace: cellular_component
def:
  "OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p." [GOC:jh, PMID:12791264, PMID:15741174]


id: GO:0055129
name: L-proline biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:ecd]


id: GO:0055130
name: D-alanine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine." [GOC:ecd]


id: GO:0055131
name: C3HC4-type RING finger domain binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway." [GOC:amm, InterPro:IPR001841, InterPro:IPR018957]


id: GO:0060001
name: minus-end directed microfilament motor activity
namespace: molecular_function
def:
  "Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers." [GOC:dph, PMID:10519557]


id: GO:0060002
name: plus-end directed microfilament motor activity
namespace: molecular_function
def:
  "Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers." [GOC:dph, PMID:10519557]


id: GO:0060004
name: reflex
namespace: biological_process
def:
  "An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness." [GOC:dph, ISBN:087797099]


id: GO:0060005
name: vestibular reflex
namespace: biological_process
def:
  "A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [PMID:11784757]


id: GO:0060006
name: angular vestibuloocular reflex
namespace: biological_process
def:
  "A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [GOC:dph, PMID:11784757]


id: GO:0060007
name: linear vestibuloocular reflex
namespace: biological_process
def:
  "A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [GOC:dph, PMID:11784757]


id: GO:0060008
name: Sertoli cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph]


id: GO:0060009
name: Sertoli cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph]


id: GO:0060011
name: Sertoli cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph]


id: GO:0060012
name: synaptic transmission, glycinergic
namespace: biological_process
def:
  "The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dph]


id: GO:0060013
name: righting reflex
namespace: biological_process
def:
  "A reflex process in which an animal immediately tries to turn over after being placed in a supine position." [GOC:dph, PMID:8635460]


id: GO:0060014
name: granulosa cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals." [GOC:dph]


id: GO:0060016
name: granulosa cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate." [GOC:dph]


id: GO:0060017
name: parathyroid gland development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone." [GOC:dph, ISBN:0721662544]


id: GO:0060018
name: astrocyte fate commitment
namespace: biological_process
def:
  "The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte." [GOC:dph]


id: GO:0060019
name: radial glial cell differentiation
namespace: biological_process
def:
  "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph]


id: GO:0060020
name: Bergmann glial cell differentiation
namespace: biological_process
def:
  "The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, PMID:10375501]


id: GO:0060021
name: palate development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544]


id: GO:0060022
name: hard palate development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes." [GOC:dph, ISBN:0721662544]


id: GO:0060023
name: soft palate development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate." [GOC:dph, ISBN:0721662544]


id: GO:0060024
name: rhythmic synaptic transmission
namespace: biological_process
def:
  "Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit." [GOC:dph]


id: GO:0060025
name: regulation of synaptic activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell." [GOC:dph, GOC:tb]


id: GO:0060026
name: convergent extension
namespace: biological_process
def:
  "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis." [GOC:dgf, GOC:dph, PMID:12062082]


id: GO:0060027
name: convergent extension involved in gastrulation
namespace: biological_process
def:
  "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:dph, PMID:12062082]


id: GO:0060028
name: convergent extension involved in axis elongation
namespace: biological_process
def:
  "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism." [GOC:dph, PMID:12062082]


id: GO:0060029
name: convergent extension involved in organogenesis
namespace: biological_process
def:
  "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ." [GOC:dph, PMID:12062082]


id: GO:0060030
name: dorsal convergence
namespace: biological_process
def:
  "The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement." [GOC:dgf, GOC:dph, PMID:12062082]


id: GO:0060031
name: mediolateral intercalation
namespace: biological_process
def:
  "The interdigitation of cells along the mediolateral axis during gastrulation." [GOC:dgf, GOC:dph, PMID:12062082]


id: GO:0060032
name: notochord regression
namespace: biological_process
def:
  "The developmental process in which the stucture of the notochord is destroyed in an embryo." [GOC:dph]


id: GO:0060033
name: anatomical structure regression
namespace: biological_process
def:
  "The developmental process in which an anatomical stucture is destroyed as a part of its normal progression." [GOC:dph]


id: GO:0060034
name: notochord cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate." [GOC:dph]


id: GO:0060035
name: notochord cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph]


id: GO:0060036
name: notochord cell vacuolation
namespace: biological_process
def:
  "The assembly and arrangement of a vacuole within a cell of the notochord." [GOC:cb, GOC:dph, PMID:10964477]


id: GO:0060037
name: pharyngeal system development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph]


id: GO:0060038
name: cardiac muscle cell proliferation
namespace: biological_process
def:
  "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571]


id: GO:0060039
name: pericardium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438]


id: GO:0060040
name: retinal bipolar neuron differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina." [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb]


id: GO:0060041
name: retina development in camera-type eye
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729]


id: GO:0060042
name: retina morphogenesis in camera-type eye
namespace: biological_process
def:
  "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu]


id: GO:0060043
name: regulation of cardiac muscle cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]


id: GO:0060044
name: negative regulation of cardiac muscle cell proliferation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]


id: GO:0060045
name: positive regulation of cardiac muscle cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]


id: GO:0060047
name: heart contraction
namespace: biological_process
def:
  "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph]


id: GO:0060049
name: regulation of protein glycosylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr]


id: GO:0060050
name: positive regulation of protein glycosylation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr]


id: GO:0060051
name: negative regulation of protein glycosylation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr]


id: GO:0060052
name: neurofilament cytoskeleton organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins." [GOC:dph]


id: GO:0060053
name: neurofilament cytoskeleton
namespace: cellular_component
def:
  "Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons." [GOC:dph]


id: GO:0060054
name: positive regulation of epithelial cell proliferation involved in wound healing
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury." [GOC:dph]


id: GO:0060055
name: angiogenesis involved in wound healing
namespace: biological_process
def:
  "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury." [GOC:dph, PMID:15039218]


id: GO:0060056
name: mammary gland involution
namespace: biological_process
def:
  "The tissue remodeling that removes differentiated mammary epithelia during weaning." [GOC:dph, PMID:15282149]


id: GO:0060057
name: apoptotic process involved in mammary gland involution
namespace: biological_process
def:
  "Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death." [GOC:dph, GOC:mtg_apoptosis]


id: GO:0060058
name: positive regulation of apoptotic process involved in mammary gland involution
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution." [GOC:dph, GOC:mtg_apoptosis, PMID:15282149]


id: GO:0060059
name: embryonic retina morphogenesis in camera-type eye
namespace: biological_process
def:
  "The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage." [GOC:dgh, GOC:dph]


id: GO:0060060
name: post-embryonic retina morphogenesis in camera-type eye
namespace: biological_process
def:
  "The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage." [GOC:dgh, GOC:dph]


id: GO:0060061
name: Spemann organizer formation
namespace: biological_process
def:
  "Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan." [GOC:bf, GOC:dph]


id: GO:0060062
name: Spemann organizer formation at the dorsal lip of the blastopore
namespace: biological_process
def:
  "Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan." [GOC:dph, PMID:9442883]


id: GO:0060063
name: Spemann organizer formation at the embryonic shield
namespace: biological_process
def:
  "Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan." [GOC:dph, PMID:9442883]


id: GO:0060064
name: Spemann organizer formation at the anterior end of the primitive streak
namespace: biological_process
def:
  "Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan." [GOC:dph, PMID:9442883]


id: GO:0060065
name: uterus development
namespace: biological_process
def:
  "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc]


id: GO:0060066
name: oviduct development
namespace: biological_process
def:
  "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct]


id: GO:0060067
name: cervix development
namespace: biological_process
def:
  "The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure." [GOC:dph, GOC:ebc]


id: GO:0060068
name: vagina development
namespace: biological_process
def:
  "The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure." [GOC:dph, GOC:ebc]


id: GO:0060069
name: Wnt signaling pathway, regulating spindle positioning
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle." [GOC:bf, GOC:dph, PMID:11532397]


id: GO:0060070
name: canonical Wnt signaling pathway
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:bf, GOC:dph, PMID:11532397, PMID:19619488]


id: GO:0060071
name: Wnt signaling pathway, planar cell polarity pathway
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity." [GOC:bf, GOC:dph, PMID:11532397]


id: GO:0060072
name: large conductance calcium-activated potassium channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729, PMID:17115074]


id: GO:0060073
name: micturition
namespace: biological_process
def:
  "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph]


id: GO:0060074
name: synapse maturation
namespace: biological_process
def:
  "The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development." [GOC:dph, GOC:ef]


id: GO:0060075
name: regulation of resting membrane potential
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized." [GOC:dph, GOC:ef, ISBN:0195088433]


id: GO:0060076
name: excitatory synapse
namespace: cellular_component
def:
  "A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef]


id: GO:0060077
name: inhibitory synapse
namespace: cellular_component
def:
  "A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef]


id: GO:0060078
name: regulation of postsynaptic membrane potential
namespace: biological_process
def:
  "Any process that modulates the potential difference across a post-synaptic membrane." [GOC:dph, GOC:ef]


id: GO:0060079
name: excitatory postsynaptic potential
namespace: biological_process
def:
  "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:dph, GOC:ef]


id: GO:0060080
name: inhibitory postsynaptic potential
namespace: biological_process
def:
  "A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential." [GOC:dph, GOC:ef]


id: GO:0060081
name: membrane hyperpolarization
namespace: biological_process
def:
  "The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential." [GOC:dph]


id: GO:0060082
name: eye blink reflex
namespace: biological_process
def:
  "The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing." [GOC:dph, PMID:2913208]


id: GO:0060083
name: smooth muscle contraction involved in micturition
namespace: biological_process
def:
  "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347]


id: GO:0060084
name: synaptic transmission involved in micturition
namespace: biological_process
def:
  "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347]


id: GO:0060085
name: smooth muscle relaxation of the bladder outlet
namespace: biological_process
def:
  "A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347]


id: GO:0060086
name: circadian temperature homeostasis
namespace: biological_process
def:
  "Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours." [GOC:dph, GOC:tb]


id: GO:0060087
name: relaxation of vascular smooth muscle
namespace: biological_process
def:
  "A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity." [GOC:dph, PMID:15867178, PMID:19996365]


id: GO:0060088
name: auditory receptor cell stereocilium organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells." [GOC:dph, PMID:10978835]


id: GO:0060089
name: molecular transducer activity
namespace: molecular_function
def:
  "The molecular function that accepts an input of one form and creates an output of a different form." [GOC:mtg_MIT_16mar07]


id: GO:0060090
name: binding, bridging
namespace: molecular_function
def:
  "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way." [GOC:mtg_MIT_16mar07, GOC:vw]


id: GO:0060091
name: kinocilium
namespace: cellular_component
def:
  "A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia." [GOC:dph, PMID:15882574]


id: GO:0060092
name: regulation of synaptic transmission, glycinergic
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph]


id: GO:0060093
name: negative regulation of synaptic transmission, glycinergic
namespace: biological_process
def:
  "Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph]


id: GO:0060094
name: positive regulation of synaptic transmission, glycinergic
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph]


id: GO:0060095
name: zinc potentiation of synaptic transmission, glycinergic
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph]


id: GO:0060096
name: serotonin secretion, neurotransmission
namespace: biological_process
def:
  "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph]


id: GO:0060097
name: cytoskeletal rearrangement involved in phagocytosis, engulfment
namespace: biological_process
def:
  "The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph]


id: GO:0060098
name: membrane reorganization involved in phagocytosis, engulfment
namespace: biological_process
def:
  "The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph]


id: GO:0060099
name: regulation of phagocytosis, engulfment
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph]


id: GO:0060100
name: positive regulation of phagocytosis, engulfment
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph]


id: GO:0060101
name: negative regulation of phagocytosis, engulfment
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph]


id: GO:0060102
name: collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060103
name: collagen and cuticulin-based cuticle extracellular matrix part
namespace: cellular_component
def:
  "Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer." [GOC:dph]


id: GO:0060104
name: surface coat of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060105
name: epicuticle of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060106
name: cortical layer of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060107
name: annuli extracellular matrix
namespace: cellular_component
def:
  "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060108
name: annular furrow extracellular matrix
namespace: cellular_component
def:
  "The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060109
name: medial layer of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060110
name: basal layer of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060111
name: alae of collagen and cuticulin-based cuticle extracellular matrix
namespace: cellular_component
def:
  "Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively." [GOC:dph, GOC:kmv, ISSN:15518507]


id: GO:0060112
name: generation of ovulation cycle rhythm
namespace: biological_process
def:
  "The process which controls the timing of the type of sexual cycle seen in female mammals." [GOC:dph]


id: GO:0060113
name: inner ear receptor cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound." [GOC:dph]


id: GO:0060114
name: vestibular receptor cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell." [GOC:dph]


id: GO:0060117
name: auditory receptor cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph]


id: GO:0060118
name: vestibular receptor cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph]


id: GO:0060119
name: inner ear receptor cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph]


id: GO:0060121
name: vestibular receptor cell stereocilium organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells." [GOC:dph]


id: GO:0060122
name: inner ear receptor stereocilium organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells." [GOC:dph]


id: GO:0060123
name: regulation of growth hormone secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph]


id: GO:0060124
name: positive regulation of growth hormone secretion
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph]


id: GO:0060125
name: negative regulation of growth hormone secretion
namespace: biological_process
def:
  "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph]


id: GO:0060126
name: somatotropin secreting cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." [GOC:dph]


id: GO:0060127
name: prolactin secreting cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." [GOC:dph]


id: GO:0060128
name: corticotropin hormone secreting cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." [GOC:dph]


id: GO:0060129
name: thyroid-stimulating hormone-secreting cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin." [GOC:dph]


id: GO:0060130
name: thyroid-stimulating hormone-secreting cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin." [GOC:dph]


id: GO:0060131
name: corticotropin hormone secreting cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." [GOC:dph]


id: GO:0060132
name: prolactin secreting cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." [GOC:dph]


id: GO:0060133
name: somatotropin secreting cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." [GOC:dph]


id: GO:0060134
name: prepulse inhibition
namespace: biological_process
def:
  "The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse." [GOC:dph, PMID:10341260]


id: GO:0060135
name: maternal process involved in female pregnancy
namespace: biological_process
def:
  "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph]


id: GO:0060136
name: embryonic process involved in female pregnancy
namespace: biological_process
def:
  "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph]


id: GO:0060139
name: positive regulation of apoptotic process by virus
namespace: biological_process
def:
  "Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:dph, GOC:mtg_apoptosis]


id: GO:0060140
name: modulation by virus of syncytium formation via plasma membrane fusion
namespace: biological_process
def:
  "The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]


id: GO:0060141
name: positive regulation of syncytium formation by virus
namespace: biological_process
def:
  "The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]


id: GO:0060142
name: regulation of syncytium formation by plasma membrane fusion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]


id: GO:0060143
name: positive regulation of syncytium formation by plasma membrane fusion
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]


id: GO:0060144
name: host cellular process involved in virus induced gene silencing
namespace: biological_process
def:
  "A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes." [GOC:dph]


id: GO:0060146
name: host gene silencing in virus induced gene silencing
namespace: biological_process
def:
  "The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection." [GOC:dph]


id: GO:0060147
name: regulation of posttranscriptional gene silencing
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph]


id: GO:0060148
name: positive regulation of posttranscriptional gene silencing
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph]


id: GO:0060149
name: negative regulation of posttranscriptional gene silencing
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph]


id: GO:0060150
name: viral triggering of virus induced gene silencing
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the inactivation of gene expression of both viral genes and host homologues to those genes by a posttranscriptional mechanism in a virally infected cell." [GOC:dph]


id: GO:0060151
name: peroxisome localization
namespace: biological_process
def:
  "Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:dph, PMID:16449325]


id: GO:0060152
name: microtubule-based peroxisome localization
namespace: biological_process
def:
  "The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:dph, PMID:16449325]


id: GO:0060153
name: modulation by virus of host cell cycle
namespace: biological_process
def:
  "Any viral process that modulates the rate or extent of progression through the cell cycle." [GOC:dph, UniProtKB-KW:KW-1121, VZ:1636]


id: GO:0060154
name: cellular process regulating host cell cycle in response to virus
namespace: biological_process
def:
  "Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus." [GOC:dph]


id: GO:0060155
name: platelet dense granule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins." [GOC:dph, PMID:11487378]


id: GO:0060156
name: milk ejection
namespace: biological_process
def:
  "An automatic response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness." [GOC:dph, GOC:mr, GOC:st]


id: GO:0060157
name: urinary bladder development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, http://en.wikipedia.org/wiki/Rhea_(bird), PMID:11768524, PMID:18276178, PMID:538956]


id: GO:0060158
name: phospholipase C-activating dopamine receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:signaling, GOC:tb, PMID:12675914]


id: GO:0060159
name: regulation of dopamine receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060160
name: negative regulation of dopamine receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060161
name: positive regulation of dopamine receptor signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060162
name: negative regulation of phospholipase C-activating dopamine receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway." [GOC:dph, GOC:tb, PMID:15016423]


id: GO:0060163
name: subpallium neuron fate commitment
namespace: biological_process
def:
  "The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon." [GOC:dph]


id: GO:0060164
name: regulation of timing of neuron differentiation
namespace: biological_process
def:
  "The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron." [GOC:dph]


id: GO:0060165
name: regulation of timing of subpallium neuron differentiation
namespace: biological_process
def:
  "The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon." [GOC:dph]


id: GO:0060166
name: olfactory pit development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx." [GOC:dph, ISBN:0124020607]


id: GO:0060167
name: regulation of adenosine receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060168
name: positive regulation of adenosine receptor signaling pathway
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060169
name: negative regulation of adenosine receptor signaling pathway
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060172
name: astral microtubule depolymerization
namespace: biological_process
def:
  "The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GOC:dph]


id: GO:0060173
name: limb development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378]


id: GO:0060174
name: limb bud formation
namespace: biological_process
def:
  "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable." [GOC:dgh, GOC:dph]


id: GO:0060175
name: brain-derived neurotrophic factor-activated receptor activity
namespace: molecular_function
def:
  "Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:dph]


id: GO:0060176
name: regulation of aggregation involved in sorocarp development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:dph, GOC:tb]


id: GO:0060177
name: regulation of angiotensin metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin." [GOC:dph, GOC:tb]


id: GO:0060178
name: regulation of exocyst localization
namespace: biological_process
def:
  "Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse." [GOC:dph, GOC:tb]


id: GO:0060179
name: male mating behavior
namespace: biological_process
def:
  "The specific behavior of a male organism that is associated with reproduction." [GOC:dph, GOC:pr, GOC:tb]


id: GO:0060180
name: female mating behavior
namespace: biological_process
def:
  "The specific behavior of a female organism that is associated with reproduction." [GOC:dph, GOC:pr, GOC:tb]


id: GO:0060183
name: apelin receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands." [GOC:dph]


id: GO:0060188
name: regulation of protein desumoylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb]


id: GO:0060189
name: positive regulation of protein desumoylation
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb]


id: GO:0060190
name: negative regulation of protein desumoylation
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb]


id: GO:0060191
name: regulation of lipase activity
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:dph, GOC:tb]


id: GO:0060192
name: negative regulation of lipase activity
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:dph, GOC:tb]


id: GO:0060193
name: positive regulation of lipase activity
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060194
name: regulation of antisense RNA transcription
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:jp, GOC:tb, PMID:18075583]


id: GO:0060195
name: negative regulation of antisense RNA transcription
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583]


id: GO:0060196
name: positive regulation of antisense RNA transcription
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583]


id: GO:0060197
name: cloacal septation
namespace: biological_process
def:
  "The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development." [GOC:dph, GOC:st]


id: GO:0060199
name: clathrin-sculpted glutamate transport vesicle
namespace: cellular_component
def:
  "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate." [GOC:dph]


id: GO:0060200
name: clathrin-sculpted acetylcholine transport vesicle
namespace: cellular_component
def:
  "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine." [GOC:dph]


id: GO:0060202
name: clathrin-sculpted acetylcholine transport vesicle lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle." [GOC:dph]


id: GO:0060204
name: clathrin-sculpted glutamate transport vesicle lumen
namespace: cellular_component
def:
  "The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle." [GOC:dph]


id: GO:0060206
name: estrous cycle phase
namespace: biological_process
def:
  "The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur." [GOC:dph]


id: GO:0060207
name: diestrus
namespace: biological_process
def:
  "The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum." [GOC:dph, ISBN:0721662544]


id: GO:0060208
name: proestrus
namespace: biological_process
def:
  "The estrous cycle phase in which there is heightened follicular activity." [GOC:dph, ISBN:0721662544]


id: GO:0060210
name: metestrus
namespace: biological_process
def:
  "The estrous cycle phase in which there is subsiding follicular function." [GOC:dph, ISBN:0721662544]


id: GO:0060211
name: regulation of nuclear-transcribed mRNA poly(A) tail shortening
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb]


id: GO:0060212
name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb]


id: GO:0060213
name: positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb]


id: GO:0060214
name: endocardium formation
namespace: biological_process
def:
  "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983]


id: GO:0060215
name: primitive hemopoiesis
namespace: biological_process
def:
  "A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells." [GOC:bf, GOC:dph, PMID:15378083, PMID:15617691]


id: GO:0060216
name: definitive hemopoiesis
namespace: biological_process
def:
  "A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood." [GOC:bf, GOC:dph, PMID:15378083, PMID:15617691]


id: GO:0060217
name: hemangioblast cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages." [GOC:bf, GOC:dph, PMID:15378083, PMID:9670018]


id: GO:0060218
name: hematopoietic stem cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083]


id: GO:0060219
name: camera-type eye photoreceptor cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060220
name: camera-type eye photoreceptor cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye." [GOC:dph]


id: GO:0060221
name: retinal rod cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph]


id: GO:0060222
name: regulation of retinal cone cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph]


id: GO:0060223
name: retinal rod cell fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph]


id: GO:0060224
name: regulation of retinal rod cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph]


id: GO:0060225
name: positive regulation of retinal rod cell fate commitment
namespace: biological_process
def:
  "Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph]


id: GO:0060226
name: negative regulation of retinal cone cell fate commitment
namespace: biological_process
def:
  "Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph]


id: GO:0060227
name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate." [GOC:dph]


id: GO:0060228
name: phosphatidylcholine-sterol O-acyltransferase activator activity
namespace: molecular_function
def:
  "Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines." [GOC:BHF, GOC:dph, GOC:tb, PMID:4335615]


id: GO:0060229
name: lipase activator activity
namespace: molecular_function
def:
  "Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060230
name: lipoprotein lipase activator activity
namespace: molecular_function
def:
  "Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein." [GOC:BHF, GOC:dph, GOC:tb, PMID:10727238]


id: GO:0060231
name: mesenchymal to epithelial transition
namespace: biological_process
def:
  "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060232
name: delamination
namespace: biological_process
def:
  "The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet." [GOC:dph, PMID:16962574, PMID:18343170]


id: GO:0060233
name: oenocyte delamination
namespace: biological_process
def:
  "The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet." [GOC:dph]


id: GO:0060234
name: neuroblast delamination
namespace: biological_process
def:
  "The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet." [GOC:dph]


id: GO:0060235
name: lens induction in camera-type eye
namespace: biological_process
def:
  "Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens." [GOC:dph, ISBN:0878932437]


id: GO:0060236
name: regulation of mitotic spindle organization
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." [GOC:ascb_2009, GOC:dph, GOC:tb]


id: GO:0060237
name: regulation of fungal-type cell wall organization
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GOC:dph, GOC:tb]


id: GO:0060238
name: regulation of signal transduction involved in conjugation with cellular fusion
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb]


id: GO:0060239
name: positive regulation of signal transduction involved in conjugation with cellular fusion
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb]


id: GO:0060240
name: negative regulation of signal transduction involved in conjugation with cellular fusion
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb]


id: GO:0060241
name: lysozyme inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan." [GOC:dph]


id: GO:0060242
name: contact inhibition
namespace: biological_process
def:
  "The cellular process in which cells stop growing or dividing in response to increased cell density." [GOC:dph, PMID:17376520]


id: GO:0060244
name: negative regulation of cell proliferation involved in contact inhibition
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density." [GOC:dph]


id: GO:0060245
name: detection of cell density
namespace: biological_process
def:
  "The series of events in which information about the density of cells in a population is received and converted into a molecular signal." [GOC:dph]


id: GO:0060246
name: detection of cell density by contact stimulus
namespace: biological_process
def:
  "The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal." [GOC:dph]


id: GO:0060247
name: detection of cell density by secreted molecule
namespace: biological_process
def:
  "The series of events in which information about the density of cells in a population is received by the detection of a secreted molecule and is converted into a molecular signal." [GOC:dph]


id: GO:0060248
name: detection of cell density by contact stimulus involved in contact inhibition
namespace: biological_process
def:
  "The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation." [GOC:dph]


id: GO:0060249
name: anatomical structure homeostasis
namespace: biological_process
def:
  "A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph]


id: GO:0060250
name: germ-line stem-cell niche homeostasis
namespace: biological_process
def:
  "A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion." [GOC:dph]


id: GO:0060251
name: regulation of glial cell proliferation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb]


id: GO:0060252
name: positive regulation of glial cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb]


id: GO:0060253
name: negative regulation of glial cell proliferation
namespace: biological_process
def:
  "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb]


id: GO:0060254
name: regulation of N-terminal protein palmitoylation
namespace: biological_process
def:
  "Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb]


id: GO:0060255
name: regulation of macromolecule metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]


id: GO:0060256
name: regulation of flocculation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms." [GOC:dph, GOC:tb]


id: GO:0060257
name: negative regulation of flocculation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms." [GOC:dph, GOC:tb]


id: GO:0060258
name: negative regulation of filamentous growth
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:dph, GOC:tb]


id: GO:0060259
name: regulation of feeding behavior
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060260
name: regulation of transcription initiation from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060261
name: positive regulation of transcription initiation from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060262
name: negative regulation of N-terminal protein palmitoylation
namespace: biological_process
def:
  "Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb]


id: GO:0060263
name: regulation of respiratory burst
namespace: biological_process
def:
  "Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb]


id: GO:0060264
name: regulation of respiratory burst involved in inflammatory response
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


id: GO:0060265
name: positive regulation of respiratory burst involved in inflammatory response
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060266
name: negative regulation of respiratory burst involved in inflammatory response
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060267
name: positive regulation of respiratory burst
namespace: biological_process
def:
  "Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb]


id: GO:0060268
name: negative regulation of respiratory burst
namespace: biological_process
def:
  "Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb]


id: GO:0060269
name: centripetally migrating follicle cell migration
namespace: biological_process
def:
  "The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte." [GOC:dph]


id: GO:0060270
name: main body follicle cell migration
namespace: biological_process
def:
  "The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte." [GOC:dph]


id: GO:0060271
name: cilium morphogenesis
namespace: biological_process
def:
  "A process that is carried out at the cellular level and in which the structure of a cilium is organized." [GOC:BHF, GOC:dph]


id: GO:0060272
name: embryonic skeletal joint morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton." [GOC:bf, GOC:BHF, GOC:dph, UBERON:0000982]


id: GO:0060273
name: crying behavior
namespace: biological_process
def:
  "The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli." [GOC:dph]


id: GO:0060274
name: maintenance of stationary phase
namespace: biological_process
def:
  "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment." [GOC:dph]


id: GO:0060275
name: maintenance of stationary phase in response to starvation
namespace: biological_process
def:
  "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment." [GOC:dph]


id: GO:0060276
name: maintenance of stationary phase in response to toxin
namespace: biological_process
def:
  "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment." [GOC:dph]


id: GO:0060277
name: obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle
namespace: biological_process
def:
  "OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle." [GOC:dph, GOC:tb]


id: GO:0060278
name: regulation of ovulation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb]


id: GO:0060279
name: positive regulation of ovulation
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb]


id: GO:0060280
name: negative regulation of ovulation
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb]


id: GO:0060281
name: regulation of oocyte development
namespace: biological_process
def:
  "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318]


id: GO:0060282
name: positive regulation of oocyte development
namespace: biological_process
def:
  "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb]


id: GO:0060283
name: negative regulation of oocyte development
namespace: biological_process
def:
  "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb]


id: GO:0060284
name: regulation of cell development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb]


id: GO:0060285
name: cilium-dependent cell motility
namespace: biological_process
def:
  "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013]


id: GO:0060287
name: epithelial cilium movement involved in determination of left/right asymmetry
namespace: biological_process
def:
  "The movement of cilia of epithelial cells resulting in the transport of signals which determine asymmetry in an organism's body plan with respect to the left and right halves." [GOC:dgh, GOC:dph, GOC:mlg]


id: GO:0060288
name: formation of a compartment boundary
namespace: biological_process
def:
  "Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier." [GOC:dph]


id: GO:0060289
name: compartment boundary maintenance
namespace: biological_process
def:
  "A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier." [GOC:dph]


id: GO:0060290
name: transdifferentiation
namespace: biological_process
def:
  "The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate." [GOC:dph, GOC:kmv]


id: GO:0060291
name: long-term synaptic potentiation
namespace: biological_process
def:
  "A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse." [GOC:dgh, GOC:dph]


id: GO:0060292
name: long term synaptic depression
namespace: biological_process
def:
  "A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse." [GOC:dgh, GOC:dph]


id: GO:0060293
name: germ plasm
namespace: cellular_component
def:
  "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." [GOC:dph]


id: GO:0060294
name: cilium movement involved in cell motility
namespace: biological_process
def:
  "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060295
name: regulation of cilium movement involved in cell motility
namespace: biological_process
def:
  "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060296
name: regulation of cilium beat frequency involved in ciliary motility
namespace: biological_process
def:
  "Any process that modulates the frequency of cilium beating involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060297
name: regulation of sarcomere organization
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060298
name: positive regulation of sarcomere organization
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060299
name: negative regulation of sarcomere organization
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060300
name: regulation of cytokine activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060301
name: positive regulation of cytokine activity
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060302
name: negative regulation of cytokine activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060303
name: regulation of nucleosome density
namespace: biological_process
def:
  "Any process that modulates the number of nucleosomes in a given region of a chromosome." [GOC:dph, GOC:tb]


id: GO:0060304
name: regulation of phosphatidylinositol dephosphorylation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol." [GOC:dph, GOC:tb]


id: GO:0060305
name: regulation of cell diameter
namespace: biological_process
def:
  "Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell." [GOC:dph, GOC:tb]


id: GO:0060306
name: regulation of membrane repolarization
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb]


id: GO:0060307
name: regulation of ventricular cardiac muscle cell membrane repolarization
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060308
name: GTP cyclohydrolase I regulator activity
namespace: molecular_function
def:
  "Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate." [GOC:dph, GOC:tb]


id: GO:0060309
name: elastin catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060310
name: regulation of elastin catabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060311
name: negative regulation of elastin catabolic process
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060312
name: regulation of blood vessel remodeling
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060313
name: negative regulation of blood vessel remodeling
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060314
name: regulation of ryanodine-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060315
name: negative regulation of ryanodine-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060316
name: positive regulation of ryanodine-sensitive calcium-release channel activity
namespace: biological_process
def:
  "Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060317
name: cardiac epithelial to mesenchymal transition
namespace: biological_process
def:
  "A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, PMID:16314491, PMID:1996351]


id: GO:0060318
name: definitive erythrocyte differentiation
namespace: biological_process
def:
  "Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis." [GOC:add, GOC:BHF, GOC:dph]


id: GO:0060319
name: primitive erythrocyte differentiation
namespace: biological_process
def:
  "Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis." [GOC:add, GOC:BHF, GOC:dph]


id: GO:0060320
name: rejection of self pollen
namespace: biological_process
def:
  "The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma." [GOC:dph, GOC:tb]


id: GO:0060321
name: acceptance of pollen
namespace: biological_process
def:
  "The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma." [GOC:dph, GOC:tb]


id: GO:0060322
name: head development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph]


id: GO:0060323
name: head morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph]


id: GO:0060324
name: face development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph]


id: GO:0060325
name: face morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph]


id: GO:0060326
name: cell chemotaxis
namespace: biological_process
def:
  "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [GOC:dph]


id: GO:0060327
name: cytoplasmic actin-based contraction involved in cell motility
namespace: biological_process
def:
  "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another." [GOC:dph]


id: GO:0060328
name: cytoplasmic actin-based contraction involved in forward cell motility
namespace: biological_process
def:
  "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell." [GOC:dph]


id: GO:0060329
name: cytoplasmic actin-based contraction involved in rearward cell motility
namespace: biological_process
def:
  "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell." [GOC:dph]


id: GO:0060330
name: regulation of response to interferon-gamma
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus." [GOC:dph]


id: GO:0060331
name: negative regulation of response to interferon-gamma
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus." [GOC:dph]


id: GO:0060333
name: interferon-gamma-mediated signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far." [GOC:add, GOC:dph, GOC:signaling, PR:000000017]


id: GO:0060334
name: regulation of interferon-gamma-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph]


id: GO:0060335
name: positive regulation of interferon-gamma-mediated signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph]


id: GO:0060336
name: negative regulation of interferon-gamma-mediated signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph]


id: GO:0060337
name: type I interferon signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:dph, GOC:signaling, PR:000025848]


id: GO:0060338
name: regulation of type I interferon-mediated signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph]


id: GO:0060339
name: negative regulation of type I interferon-mediated signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph]


id: GO:0060340
name: positive regulation of type I interferon-mediated signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph]


id: GO:0060341
name: regulation of cellular localization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb]


id: GO:0060342
name: photoreceptor inner segment membrane
namespace: cellular_component
def:
  "The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs." [GOC:dph]


id: GO:0060343
name: trabecula formation
namespace: biological_process
def:
  "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]


id: GO:0060344
name: liver trabecula formation
namespace: biological_process
def:
  "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]


id: GO:0060345
name: spleen trabecula formation
namespace: biological_process
def:
  "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]


id: GO:0060346
name: bone trabecula formation
namespace: biological_process
def:
  "The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]


id: GO:0060347
name: heart trabecula formation
namespace: biological_process
def:
  "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]


id: GO:0060348
name: bone development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph]


id: GO:0060350
name: endochondral bone morphogenesis
namespace: biological_process
def:
  "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679]


id: GO:0060351
name: cartilage development involved in endochondral bone morphogenesis
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph]


id: GO:0060353
name: regulation of cell adhesion molecule production
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl]


id: GO:0060354
name: negative regulation of cell adhesion molecule production
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl]


id: GO:0060355
name: positive regulation of cell adhesion molecule production
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl]


id: GO:0060357
name: regulation of leucine import
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb]


id: GO:0060358
name: negative regulation of leucine import
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb]


id: GO:0060359
name: response to ammonium ion
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus." [GOC:dph, GOC:tb]


id: GO:0060360
name: negative regulation of leucine import in response to ammonium ion
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb]


id: GO:0060361
name: flight
namespace: biological_process
def:
  "Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement." [GOC:dph]


id: GO:0060362
name: flight involved in flight behavior
namespace: biological_process
def:
  "Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight." [GOC:dph]


id: GO:0060363
name: cranial suture morphogenesis
namespace: biological_process
def:
  "The process in which any suture between cranial bones is generated and organized." [GOC:dph, GOC:pr, GOC:sl]


id: GO:0060368
name: regulation of Fc receptor mediated stimulatory signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:dph, GOC:tb]


id: GO:0060369
name: positive regulation of Fc receptor mediated stimulatory signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060370
name: susceptibility to T cell mediated cytotoxicity
namespace: biological_process
def:
  "The process of causing a cell to become susceptible to T cell mediated cytotoxicity." [GOC:dph, GOC:tb]


id: GO:0060371
name: regulation of atrial cardiac muscle cell membrane depolarization
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte." [GOC:dph, GOC:tb]


id: GO:0060372
name: regulation of atrial cardiac muscle cell membrane repolarization
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte." [GOC:dph, GOC:tb]


id: GO:0060373
name: regulation of ventricular cardiac muscle cell membrane depolarization
namespace: biological_process
def:
  "Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte." [GOC:dph, GOC:tb]


id: GO:0060374
name: mast cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb]


id: GO:0060375
name: regulation of mast cell differentiation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb]


id: GO:0060376
name: positive regulation of mast cell differentiation
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb]


id: GO:0060377
name: negative regulation of mast cell differentiation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb]


id: GO:0060378
name: regulation of brood size
namespace: biological_process
def:
  "Any process that modulates the extent of brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." [GOC:dph, GOC:tb]


id: GO:0060379
name: cardiac muscle cell myoblast differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb]


id: GO:0060380
name: regulation of single-stranded telomeric DNA binding
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA." [GOC:dph, GOC:tb]


id: GO:0060381
name: positive regulation of single-stranded telomeric DNA binding
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060382
name: regulation of DNA strand elongation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand." [GOC:dph, GOC:tb]


id: GO:0060383
name: positive regulation of DNA strand elongation
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060384
name: innervation
namespace: biological_process
def:
  "The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue." [GOC:dph, GOC:sart]


id: GO:0060385
name: axonogenesis involved in innervation
namespace: biological_process
def:
  "The neurite development process that generates a long process of a neuron, as it invades a target tissue." [GOC:dph, GOC:sart]


id: GO:0060386
name: synapse assembly involved in innervation
namespace: biological_process
def:
  "The assembly of a synapse within a target tissue in which a nerve is invading." [GOC:dph, GOC:pr, GOC:sart]


id: GO:0060387
name: fertilization envelope
namespace: cellular_component
def:
  "A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release." [GOC:dph, ISBN:0878932437]


id: GO:0060388
name: vitelline envelope
namespace: cellular_component
def:
  "A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization." [GOC:dph, ISBN:0878932437]


id: GO:0060389
name: pathway-restricted SMAD protein phosphorylation
namespace: biological_process
def:
  "The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor." [GOC:dph, ISBN:3527303782]


id: GO:0060390
name: regulation of SMAD protein import into nucleus
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060391
name: positive regulation of SMAD protein import into nucleus
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060392
name: negative regulation of SMAD protein import into nucleus
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060393
name: regulation of pathway-restricted SMAD protein phosphorylation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060394
name: negative regulation of pathway-restricted SMAD protein phosphorylation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060395
name: SMAD protein signal transduction
namespace: biological_process
def:
  "The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060396
name: growth hormone receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph, PMID:11445442]


id: GO:0060397
name: JAK-STAT cascade involved in growth hormone signaling pathway
namespace: biological_process
def:
  "The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes." [GOC:BHF, GOC:dph, PMID:11445442]


id: GO:0060398
name: regulation of growth hormone receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph]


id: GO:0060399
name: positive regulation of growth hormone receptor signaling pathway
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph]


id: GO:0060400
name: negative regulation of growth hormone receptor signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:dph]


id: GO:0060401
name: cytosolic calcium ion transport
namespace: biological_process
def:
  "The directed movement of calcium ions (Ca2+) into, out of or within the cytosol." [GOC:dph, GOC:tb]


id: GO:0060403
name: post-mating oviposition
namespace: biological_process
def:
  "The deposition of eggs, either fertilized or not, upon a surface or into a medium, following mating." [GOC:dph, GOC:tb]


id: GO:0060404
name: axonemal microtubule depolymerization
namespace: biological_process
def:
  "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:dph, GOC:tb]


id: GO:0060405
name: regulation of penile erection
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:add, GOC:dph, GOC:tb]


id: GO:0060406
name: positive regulation of penile erection
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:dph, GOC:tb]


id: GO:0060408
name: regulation of acetylcholine metabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]


id: GO:0060409
name: positive regulation of acetylcholine metabolic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]


id: GO:0060410
name: negative regulation of acetylcholine metabolic process
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]


id: GO:0060411
name: cardiac septum morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart]


id: GO:0060412
name: ventricular septum morphogenesis
namespace: biological_process
def:
  "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph]


id: GO:0060413
name: atrial septum morphogenesis
namespace: biological_process
def:
  "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart]


id: GO:0060414
name: aorta smooth muscle tissue morphogenesis
namespace: biological_process
def:
  "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta]


id: GO:0060415
name: muscle tissue morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph]


id: GO:0060416
name: response to growth hormone
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth." [GOC:BHF, GOC:dph]


id: GO:0060417
name: yolk
namespace: cellular_component
def:
  "The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo." [GOC:dph, GOC:tb, PMID:18046696]


id: GO:0060418
name: yolk plasma
namespace: cellular_component
def:
  "Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed." [GOC:dph, GOC:tb, PMID:18046696]


id: GO:0060420
name: regulation of heart growth
namespace: biological_process
def:
  "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb]


id: GO:0060421
name: positive regulation of heart growth
namespace: biological_process
def:
  "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060422
name: peptidyl-dipeptidase inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain." [GOC:dph, GOC:tb]


id: GO:0060423
name: foregut regionalization
namespace: biological_process
def:
  "The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place." [GOC:dph, GOC:mtg_lung]


id: GO:0060424
name: lung field specification
namespace: biological_process
def:
  "The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop." [GOC:dph, GOC:mtg_lung]


id: GO:0060426
name: lung vasculature development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung]


id: GO:0060427
name: lung connective tissue development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung]


id: GO:0060428
name: lung epithelium development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung]


id: GO:0060429
name: epithelium development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung]


id: GO:0060430
name: lung saccule development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells." [GOC:dph, GOC:mtg_lung]


id: GO:0060431
name: primary lung bud formation
namespace: biological_process
def:
  "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung]


id: GO:0060432
name: lung pattern specification process
namespace: biological_process
def:
  "Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate." [GOC:dph]


id: GO:0060433
name: bronchus development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph]


id: GO:0060434
name: bronchus morphogenesis
namespace: biological_process
def:
  "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph]


id: GO:0060435
name: bronchiole development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph, GOC:mtg_lung]


id: GO:0060436
name: bronchiole morphogenesis
namespace: biological_process
def:
  "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph]


id: GO:0060437
name: lung growth
namespace: biological_process
def:
  "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph]


id: GO:0060438
name: trachea development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]


id: GO:0060439
name: trachea morphogenesis
namespace: biological_process
def:
  "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]


id: GO:0060440
name: trachea formation
namespace: biological_process
def:
  "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]


id: GO:0060441
name: epithelial tube branching involved in lung morphogenesis
namespace: biological_process
def:
  "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung]


id: GO:0060442
name: branching involved in prostate gland morphogenesis
namespace: biological_process
def:
  "The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph]


id: GO:0060443
name: mammary gland morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph]


id: GO:0060444
name: branching involved in mammary gland duct morphogenesis
namespace: biological_process
def:
  "The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph]


id: GO:0060445
name: branching involved in salivary gland morphogenesis
namespace: biological_process
def:
  "The process in which the branching structure of the salivary gland is generated and organized." [GOC:dph]


id: GO:0060446
name: branching involved in open tracheal system development
namespace: biological_process
def:
  "The process in which the anatomical structures of branches in the open tracheal system are generated and organized." [GOC:dph]


id: GO:0060447
name: bud outgrowth involved in lung branching
namespace: biological_process
def:
  "The process in which a region of the lung epithelium initiates an outgrowth." [GOC:dph, GOC:mtg_lung]


id: GO:0060449
name: bud elongation involved in lung branching
namespace: biological_process
def:
  "The process in which a bud in the lung grows out from the point where it is formed." [GOC:dph, GOC:mtg_lung]


id: GO:0060450
name: positive regulation of hindgut contraction
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb]


id: GO:0060451
name: negative regulation of hindgut contraction
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb]


id: GO:0060452
name: positive regulation of cardiac muscle contraction
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb]


id: GO:0060453
name: regulation of gastric acid secretion
namespace: biological_process
def:
  "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]


id: GO:0060454
name: positive regulation of gastric acid secretion
namespace: biological_process
def:
  "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]


id: GO:0060455
name: negative regulation of gastric acid secretion
namespace: biological_process
def:
  "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]


id: GO:0060456
name: positive regulation of digestive system process
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb]


id: GO:0060457
name: negative regulation of digestive system process
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb]


id: GO:0060458
name: right lung development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung]


id: GO:0060459
name: left lung development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung]


id: GO:0060460
name: left lung morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph]


id: GO:0060461
name: right lung morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung]


id: GO:0060462
name: lung lobe development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph]


id: GO:0060463
name: lung lobe morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph]


id: GO:0060464
name: lung lobe formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph]


id: GO:0060465
name: pharynx development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk]


id: GO:0060466
name: activation of meiosis involved in egg activation
namespace: biological_process
def:
  "Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation." [GOC:dph]


id: GO:0060467
name: negative regulation of fertilization
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph]


id: GO:0060468
name: prevention of polyspermy
namespace: biological_process
def:
  "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph]


id: GO:0060469
name: positive regulation of transcription involved in egg activation
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation." [GOC:dph]


id: GO:0060470
name: positive regulation of cytosolic calcium ion concentration involved in egg activation
namespace: biological_process
def:
  "The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg." [GOC:dph]


id: GO:0060471
name: cortical granule exocytosis
namespace: biological_process
def:
  "The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy." [GOC:dph]


id: GO:0060472
namespace: biological_process
name:
  positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration

def:
  "Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol." [GOC:dph]


id: GO:0060473
name: cortical granule
namespace: cellular_component
def:
  "A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy." [GOC:dph]


id: GO:0060474
name: positive regulation of sperm motility involved in capacitation
namespace: biological_process
def:
  "The process in which the controlled movement of a sperm cell is initiated as part of the process required for sperm to reach fertilization competence." [GOC:dph]


id: GO:0060475
name: positive regulation of actin filament polymerization involved in acrosome reaction
namespace: biological_process
def:
  "Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction." [GOC:dph]


id: GO:0060476
name: protein localization involved in acrosome reaction
namespace: biological_process
def:
  "The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction." [GOC:dph]


id: GO:0060477
name: peptidyl-serine phosphorylation involved in acrosome reaction
namespace: biological_process
def:
  "The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction." [GOC:dph]


id: GO:0060478
name: acrosomal vesicle exocytosis
namespace: biological_process
def:
  "The release of intracellular molecules contained within the acrosomal granule by fusion of the vesicle with the plasma membrane of the oocyte, requiring calcium ions." [GOC:dph]


id: GO:0060479
name: lung cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung]


id: GO:0060480
name: lung goblet cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins." [GOC:dph, GOC:mtg_lung]


id: GO:0060481
name: lobar bronchus epithelium development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus." [GOC:dph, GOC:mtg_lung]


id: GO:0060482
name: lobar bronchus development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi." [GOC:dph, GOC:mtg_lung]


id: GO:0060483
name: lobar bronchus mesenchyme development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus." [GOC:dph, GOC:mtg_lung]


id: GO:0060484
name: lung-associated mesenchyme development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung." [GOC:dph, GOC:mtg_lung]


id: GO:0060485
name: mesenchyme development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph]


id: GO:0060486
name: Clara cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles." [GOC:dph, GOC:mtg_lung]


id: GO:0060487
name: lung epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph]


id: GO:0060488
name: orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
namespace: biological_process
def:
  "The process in which a lung bud bifurcates perpendicular to the plane of the previous bud." [GOC:dph, GOC:mtg_lung]


id: GO:0060489
name: planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
namespace: biological_process
def:
  "The process in which a lung bud bifurcates parallel to the plane of the previous bud." [GOC:dph, GOC:mtg_lung]


id: GO:0060490
name: lateral sprouting involved in lung morphogenesis
namespace: biological_process
def:
  "The process in which a branch forms along the side of the lung epithelial tube." [GOC:dph, GOC:mtg_lung]


id: GO:0060491
name: regulation of cell projection assembly
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb]


id: GO:0060492
name: lung induction
namespace: biological_process
def:
  "The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung." [GOC:dph]


id: GO:0060493
name: mesenchymal-endodermal cell signaling involved in lung induction
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud." [GOC:dph, GOC:mtg_lung]


id: GO:0060494
name: inductive mesenchymal-endodermal cell signaling
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell." [GOC:dph, GOC:mtg_lung]


id: GO:0060495
name: cell-cell signaling involved in lung development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung]


id: GO:0060496
name: mesenchymal-epithelial cell signaling involved in lung development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung]


id: GO:0060497
name: mesenchymal-endodermal cell signaling
namespace: biological_process
def:
  "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph]


id: GO:0060498
name: retinoic acid receptor signaling pathway involved in lung bud formation
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud." [GOC:dph, GOC:mtg_lung]


id: GO:0060499
name: fibroblast growth factor receptor signaling pathway involved in lung induction
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus." [GOC:dph, GOC:mtg_lung]


id: GO:0060500
name: regulation of transcription from RNA polymerase II promoter involved in lung bud formation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed." [GOC:dph, GOC:mtg_lung]


id: GO:0060501
name: positive regulation of epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def:
  "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph]


id: GO:0060502
name: epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph]


id: GO:0060504
name: positive regulation of epithelial cell proliferation involved in lung bud dilation
namespace: biological_process
def:
  "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially." [GOC:dph]


id: GO:0060505
name: epithelial cell proliferation involved in lung bud dilation
namespace: biological_process
def:
  "The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud." [GOC:dph]


id: GO:0060506
name: smoothened signaling pathway involved in lung development
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development." [GOC:dph, GOC:mtg_lung]


id: GO:0060507
name: epidermal growth factor receptor signaling pathway involved in lung development
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development." [GOC:dph, GOC:mtg_lung]


id: GO:0060508
name: lung basal cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell." [GOC:dph, GOC:mtg_lung]


id: GO:0060509
name: Type I pneumocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles." [GOC:dph, GOC:mtg_lung, ISBN:0721662544]


id: GO:0060510
name: Type II pneumocyte differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a Type II pneumocyte. A Type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies." [GOC:dph, GOC:mtg_lung, ISBN:0721662544]


id: GO:0060511
name: creation of an inductive signal by a mesenchymal cell involved in lung induction
namespace: biological_process
def:
  "The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud." [GOC:dph, GOC:mtg_lung]


id: GO:0060512
name: prostate gland morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a prostate gland are generated and organized." [GOC:dph, PMID:18977204]


id: GO:0060513
name: prostatic bud formation
namespace: biological_process
def:
  "The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph, PMID:18977204]


id: GO:0060514
name: prostate induction
namespace: biological_process
def:
  "The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland." [GOC:dph, PMID:18977204]


id: GO:0060515
name: prostate field specification
namespace: biological_process
def:
  "The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop." [GOC:dph, PMID:18977204]


id: GO:0060517
name: epithelial cell proliferation involved in prostatic bud elongation
namespace: biological_process
def:
  "The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud." [GOC:dph, PMID:18977204]


id: GO:0060518
name: cell migration involved in prostatic bud elongation
namespace: biological_process
def:
  "The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]


id: GO:0060519
name: cell adhesion involved in prostatic bud elongation
namespace: biological_process
def:
  "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204]


id: GO:0060520
name: activation of prostate induction by androgen receptor signaling pathway
namespace: biological_process
def:
  "Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland." [GOC:dph, GOC:tb, PMID:18977204]


id: GO:0060521
name: mesenchymal-epithelial cell signaling involved in prostate induction
namespace: biological_process
def:
  "Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate." [GOC:dph, PMID:18977204]


id: GO:0060522
name: inductive mesenchymal to epithelial cell signaling
namespace: biological_process
def:
  "Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells." [GOC:dph]


id: GO:0060523
name: prostate epithelial cord elongation
namespace: biological_process
def:
  "The developmental growth process in which solid chords of prostate epithelium increase in length." [GOC:dph, PMID:18977204]


id: GO:0060525
name: prostate glandular acinus development
namespace: biological_process
def:
  "The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland." [GOC:dph, PMID:18977204]


id: GO:0060526
name: prostate glandular acinus morphogenesis
namespace: biological_process
def:
  "The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland." [GOC:dph]


id: GO:0060527
name: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
namespace: biological_process
def:
  "The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini." [GOC:dph, PMID:18977204]


id: GO:0060528
namespace: biological_process
name:
  secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

def:
  "The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate." [GOC:dph, PMID:18977204]


id: GO:0060529
name: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate." [GOC:dph, PMID:18977204]


id: GO:0060530
name: smooth muscle cell differentiation involved in prostate glandular acinus development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus." [GOC:dph, PMID:18977204]


id: GO:0060531
name: neuroendocrine cell differentiation involved in prostate gland acinus development
namespace: biological_process
def:
  "The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus." [GOC:dph, PMID:18977204]


id: GO:0060532
name: bronchus cartilage development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph, GOC:mtg_lung]


id: GO:0060533
name: bronchus cartilage morphogenesis
namespace: biological_process
def:
  "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." [GOC:dph]


id: GO:0060534
name: trachea cartilage development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]


id: GO:0060535
name: trachea cartilage morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of cartilage in the trachea are generated and organized." [GOC:dph]


id: GO:0060536
name: cartilage morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph]


id: GO:0060537
name: muscle tissue development
namespace: biological_process
def:
  "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph]


id: GO:0060538
name: skeletal muscle organ development
namespace: biological_process
def:
  "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph]


id: GO:0060539
name: diaphragm development
namespace: biological_process
def:
  "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph]


id: GO:0060540
name: diaphragm morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph]


id: GO:0060541
name: respiratory system development
namespace: biological_process
def:
  "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph]


id: GO:0060542
name: regulation of strand invasion
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:dph, GOC:tb]


id: GO:0060543
name: negative regulation of strand invasion
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:dph, GOC:elh, GOC:tb]


id: GO:0060544
name: regulation of necroptotic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


id: GO:0060545
name: positive regulation of necroptotic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


id: GO:0060546
name: negative regulation of necroptotic process
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


id: GO:0060547
name: negative regulation of necrotic cell death
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060548
name: negative regulation of cell death
namespace: biological_process
def:
  "Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060549
name: regulation of fructose 1,6-bisphosphate 1-phosphatase activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060550
name: positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060551
name: regulation of fructose 1,6-bisphosphate metabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060552
name: positive regulation of fructose 1,6-bisphosphate metabolic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060556
name: regulation of vitamin D biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [CHEBI:27300, GOC:BHF, GOC:mah, ISBN:0471331309]


id: GO:0060557
name: positive regulation of vitamin D biosynthetic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [CHEBI:27300, GOC:BHF, GOC:mah, ISBN:0471331309]


id: GO:0060558
name: regulation of calcidiol 1-monooxygenase activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060559
name: positive regulation of calcidiol 1-monooxygenase activity
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060560
name: developmental growth involved in morphogenesis
namespace: biological_process
def:
  "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph]


id: GO:0060561
name: apoptotic process involved in morphogenesis
namespace: biological_process
def:
  "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis]


id: GO:0060562
name: epithelial tube morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph]


id: GO:0060563
name: neuroepithelial cell differentiation
namespace: biological_process
def:
  "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb]


id: GO:0060564
name: negative regulation of APC-Cdc20 complex activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of APC-Cdc20 complex activity regulating mitotic cell cycle transitions." [GOC:dph, GOC:tb]


id: GO:0060565
name: obsolete inhibition of APC-Cdc20 complex activity
namespace: biological_process
def:
  "OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle." [GOC:dph, GOC:tb]


id: GO:0060566
name: positive regulation of DNA-templated transcription, termination
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060567
name: negative regulation of DNA-templated transcription, termination
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060568
name: regulation of peptide hormone processing
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]


id: GO:0060569
name: positive regulation of peptide hormone processing
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]


id: GO:0060570
name: negative regulation of peptide hormone processing
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb]


id: GO:0060572
name: morphogenesis of an epithelial bud
namespace: biological_process
def:
  "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph]


id: GO:0060573
name: cell fate specification involved in pattern specification
namespace: biological_process
def:
  "The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:dph, GOC:tb]


id: GO:0060574
name: intestinal epithelial cell maturation
namespace: biological_process
def:
  "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147]


id: GO:0060575
name: intestinal epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph]


id: GO:0060576
name: intestinal epithelial cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph]


id: GO:0060577
name: pulmonary vein morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph]


id: GO:0060578
name: superior vena cava morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph]


id: GO:0060579
name: ventral spinal cord interneuron fate commitment
namespace: biological_process
def:
  "The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses." [GOC:dph]


id: GO:0060580
name: ventral spinal cord interneuron fate determination
namespace: biological_process
def:
  "The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses." [GOC:dph]


id: GO:0060581
name: cell fate commitment involved in pattern specification
namespace: biological_process
def:
  "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph]


id: GO:0060582
name: cell fate determination involved in pattern specification
namespace: biological_process
def:
  "A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:dph]


id: GO:0060583
name: regulation of actin cortical patch localization
namespace: biological_process
def:
  "Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells." [GOC:dph, GOC:tb]


id: GO:0060584
name: regulation of prostaglandin-endoperoxide synthase activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060585
name: positive regulation of prostaglandin-endoperoxide synthase activity
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060586
name: multicellular organismal iron ion homeostasis
namespace: biological_process
def:
  "Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism." [GOC:dph, GOC:hjd, GOC:tb]


id: GO:0060587
name: regulation of lipoprotein lipid oxidation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060588
name: negative regulation of lipoprotein lipid oxidation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060591
name: chondroblast differentiation
namespace: biological_process
def:
  "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph]


id: GO:0060592
name: mammary gland formation
namespace: biological_process
def:
  "The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme." [GOC:dph, PMID:16168142, PMID:17120154]


id: GO:0060593
name: Wnt signaling pathway involved in mammary gland specification
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph, PMID:16168142]


id: GO:0060594
name: mammary gland specification
namespace: biological_process
def:
  "The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph]


id: GO:0060595
name: fibroblast growth factor receptor signaling pathway involved in mammary gland specification
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph, PMID:16168142]


id: GO:0060596
name: mammary placode formation
namespace: biological_process
def:
  "The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper." [GOC:dph, PMID:16168142]


id: GO:0060597
name: regulation of transcription from RNA polymerase II promoter involved in mammary gland formation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud." [GOC:dph, PMID:16168142]


id: GO:0060603
name: mammary gland duct morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk." [GOC:dph, PMID:17120154]


id: GO:0060604
name: mammary gland duct cavitation
namespace: biological_process
def:
  "Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod." [GOC:dph, PMID:17120154]


id: GO:0060606
name: tube closure
namespace: biological_process
def:
  "Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold." [GOC:dph]


id: GO:0060607
name: cell-cell adhesion involved in sealing an epithelial fold
namespace: biological_process
def:
  "The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube." [GOC:dph]


id: GO:0060608
name: cell-cell adhesion involved in neural tube closure
namespace: biological_process
def:
  "The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube." [GOC:dph]


id: GO:0060609
name: apoptotic process involved in tube lumen cavitation
namespace: biological_process
def:
  "Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube." [GOC:dph, GOC:mtg_apoptosis]


id: GO:0060610
name: mesenchymal cell differentiation involved in mammary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts." [GOC:dph]


id: GO:0060611
name: mammary gland fat development
namespace: biological_process
def:
  "The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts." [GOC:dph]


id: GO:0060612
name: adipose tissue development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph]


id: GO:0060613
name: fat pad development
namespace: biological_process
def:
  "The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue." [GOC:dph]


id: GO:0060614
name: negative regulation of mammary gland development in males by androgen receptor signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell." [GOC:dph]


id: GO:0060615
name: mammary gland bud formation
namespace: biological_process
def:
  "The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis." [GOC:dph, PMID:12558599]


id: GO:0060616
name: mammary gland cord formation
namespace: biological_process
def:
  "The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad." [GOC:dph, PMID:12558599]


id: GO:0060617
name: positive regulation of mammary placode formation by mesenchymal-epithelial signaling
namespace: biological_process
def:
  "Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode." [GOC:dph, PMID:12558599]


id: GO:0060618
name: nipple development
namespace: biological_process
def:
  "The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm." [GOC:dph]


id: GO:0060619
name: cell migration involved in mammary placode formation
namespace: biological_process
def:
  "The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode." [GOC:dph, PMID:12558599]


id: GO:0060620
name: regulation of cholesterol import
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060621
name: negative regulation of cholesterol import
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060622
name: regulation of ascospore wall beta-glucan biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:dph, GOC:tb]


id: GO:0060623
name: regulation of chromosome condensation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb]


id: GO:0060624
name: regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores." [GOC:dph, GOC:tb]


id: GO:0060625
name: regulation of protein deneddylation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein." [GOC:dph, GOC:tb]


id: GO:0060626
name: regulation of cullin deneddylation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of cullin deneddylation, the modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1)." [GOC:dph, GOC:tb]


id: GO:0060627
name: regulation of vesicle-mediated transport
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb]


id: GO:0060628
name: regulation of ER to Golgi vesicle-mediated transport
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi." [GOC:dph, GOC:tb]


id: GO:0060629
name: regulation of homologous chromosome segregation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:dph, GOC:tb]


id: GO:0060630
name: obsolete regulation of M/G1 transition of mitotic cell cycle
namespace: biological_process
def:
  "OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle." [GOC:dph, GOC:mtg_cell_cycle, GOC:tb]


id: GO:0060631
name: regulation of meiosis I
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [GOC:dph, GOC:tb]


id: GO:0060632
name: regulation of microtubule-based movement
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb]


id: GO:0060633
name: negative regulation of transcription initiation from RNA polymerase II promoter
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH]


id: GO:0060634
name: regulation of 4,6-pyruvylated galactose residue biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain." [GOC:dph, GOC:tb]


id: GO:0060635
name: positive regulation of (1->3)-beta-D-glucan biosynthetic process
namespace: biological_process
def:
  "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans." [GOC:dph, GOC:tb]


id: GO:0060636
name: negative regulation of (1->3)-beta-D-glucan biosynthetic process
namespace: biological_process
def:
  "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans." [GOC:dph, GOC:tb]


id: GO:0060637
name: positive regulation of lactation by mesenchymal-epithelial cell signaling
namespace: biological_process
def:
  "The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell." [GOC:dph, PMID:12558599]


id: GO:0060638
name: mesenchymal-epithelial cell signaling
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph]


id: GO:0060639
name: positive regulation of salivary gland formation by mesenchymal-epithelial signaling
namespace: biological_process
def:
  "Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell." [GOC:dph]


id: GO:0060640
name: positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling
namespace: biological_process
def:
  "Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud." [GOC:dph]


id: GO:0060641
name: mammary gland duct regression in males
namespace: biological_process
def:
  "The process in which the epithelium of the mammary duct is destroyed in males." [GOC:dph, PMID:12558599]


id: GO:0060642
name: white fat cell differentiation involved in mammary gland fat development
namespace: biological_process
def:
  "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole." [GOC:dph, PMID:12558599]


id: GO:0060643
name: epithelial cell differentiation involved in mammary gland bud morphogenesis
namespace: biological_process
def:
  "The process in which a cell of the mammary placode becomes a cell of the mammary gland bud." [GOC:dph]


id: GO:0060644
name: mammary gland epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland." [GOC:dph]


id: GO:0060645
name: peripheral mammary gland bud epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically." [GOC:dph, PMID:12558599]


id: GO:0060646
name: internal mammary gland bud epithelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape." [GOC:dph, PMID:12558599]


id: GO:0060647
name: mesenchymal cell condensation involved in mammary fat development
namespace: biological_process
def:
  "The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development." [GOC:dph, PMID:12558599]


id: GO:0060648
name: mammary gland bud morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord." [GOC:dph, PMID:12558599]


id: GO:0060650
name: epithelial cell proliferation involved in mammary gland bud elongation
namespace: biological_process
def:
  "The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud." [GOC:dph, PMID:12558599]


id: GO:0060651
name: regulation of epithelial cell proliferation involved in mammary gland bud elongation
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud." [GOC:dph, PMID:12558599]


id: GO:0060652
name: mammary gland cord morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat." [GOC:dph, PMID:12558599]


id: GO:0060653
name: epithelial cell differentiation involved in mammary gland cord morphogenesis
namespace: biological_process
def:
  "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified." [GOC:dph, PMID:12558599]


id: GO:0060655
name: branching involved in mammary gland cord morphogenesis
namespace: biological_process
def:
  "The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct." [GOC:dph, PMID:12558599]


id: GO:0060656
namespace: biological_process
name:
  regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling

def:
  "Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell." [GOC:dph, PMID:12558599]


id: GO:0060657
name: regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell." [GOC:dph, PMID:12558599]


id: GO:0060659
name: nipple sheath formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate." [GOC:dph, PMID:12558599]


id: GO:0060660
name: epidermis morphogenesis involved in nipple formation
namespace: biological_process
def:
  "The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection." [GOC:dph, PMID:12558599]


id: GO:0060661
name: submandibular salivary gland formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed." [GOC:dph, PMID:17336109]


id: GO:0060662
name: salivary gland cavitation
namespace: biological_process
def:
  "The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland." [GOC:dph]


id: GO:0060663
name: apoptotic process involved in salivary gland cavitation
namespace: biological_process
def:
  "Any apoptotic process in which the solid core of the gland is hollowed out to form the duct." [GOC:dph, GOC:mtg_apoptosis, PMID:17336109]


id: GO:0060664
name: epithelial cell proliferation involved in salivary gland morphogenesis
namespace: biological_process
def:
  "The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland." [GOC:dph, PMID:17336109]


id: GO:0060665
namespace: biological_process
name:
  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

def:
  "Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium." [GOC:dph, PMID:17336109]


id: GO:0060667
name: branch elongation involved in salivary gland morphogenesis
namespace: biological_process
def:
  "The differential growth of the salivary branches along their axis, resulting in the growth of a branch." [GOC:dph]


id: GO:0060668
namespace: biological_process
name:
  regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling

def:
  "Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland." [GOC:dph]


id: GO:0060670
name: branching involved in labyrinthine layer morphogenesis
namespace: biological_process
def:
  "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377]


id: GO:0060671
name: epithelial cell differentiation involved in embryonic placenta development
namespace: biological_process
def:
  "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377]


id: GO:0060672
name: epithelial cell morphogenesis involved in placental branching
namespace: biological_process
def:
  "The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:16916377]


id: GO:0060673
name: cell-cell signaling involved in placenta development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377]


id: GO:0060674
name: placenta blood vessel development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377]


id: GO:0060676
name: ureteric bud formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378]


id: GO:0060677
name: ureteric bud elongation
namespace: biological_process
def:
  "The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated." [GOC:dph, PMID:16916378]


id: GO:0060682
name: primary ureteric bud growth
namespace: biological_process
def:
  "The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema." [GOC:dph, PMID:16916378]


id: GO:0060683
namespace: biological_process
name:
  regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

def:
  "Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland." [GOC:dph, PMID:18559345]


id: GO:0060684
name: epithelial-mesenchymal cell signaling
namespace: biological_process
def:
  "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph]


id: GO:0060685
name: regulation of prostatic bud formation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph]


id: GO:0060686
name: negative regulation of prostatic bud formation
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph]


id: GO:0060687
name: regulation of branching involved in prostate gland morphogenesis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph]


id: GO:0060688
name: regulation of morphogenesis of a branching structure
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph]


id: GO:0060689
name: cell differentiation involved in salivary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland." [GOC:dph]


id: GO:0060690
name: epithelial cell differentiation involved in salivary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland." [GOC:dph]


id: GO:0060691
name: epithelial cell maturation involved in salivary gland development
namespace: biological_process
def:
  "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state." [GOC:dph]


id: GO:0060692
name: mesenchymal cell differentiation involved in salivary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph]


id: GO:0060693
name: regulation of branching involved in salivary gland morphogenesis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium." [GOC:dph]


id: GO:0060694
name: regulation of cholesterol transporter activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of cholesterol transporter activity." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060695
name: negative regulation of cholesterol transporter activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of cholesterol transporter activity." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060696
name: regulation of phospholipid catabolic process
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060697
name: positive regulation of phospholipid catabolic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060698
name: endoribonuclease inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb]


id: GO:0060699
name: regulation of endoribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb]


id: GO:0060700
name: regulation of ribonuclease activity
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:dph, GOC:tb]


id: GO:0060701
name: negative regulation of ribonuclease activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:dph, GOC:tb]


id: GO:0060702
name: negative regulation of endoribonuclease activity
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb]


id: GO:0060704
name: acinar cell differentiation involved in salivary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland." [GOC:dph, GOC:tb]


id: GO:0060705
name: neuron differentiation involved in salivary gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland." [GOC:dph]


id: GO:0060706
name: cell differentiation involved in embryonic placenta development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph]


id: GO:0060707
name: trophoblast giant cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua." [GOC:dph, PMID:16269175]


id: GO:0060708
name: spongiotrophoblast differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell." [GOC:dph, PMID:16269175]


id: GO:0060709
name: glycogen cell differentiation involved in embryonic placenta development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer." [GOC:dph, PMID:16269175]


id: GO:0060710
name: chorio-allantoic fusion
namespace: biological_process
def:
  "The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois." [GOC:dph]


id: GO:0060711
name: labyrinthine layer development
namespace: biological_process
def:
  "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph]


id: GO:0060712
name: spongiotrophoblast layer development
namespace: biological_process
def:
  "The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state." [GOC:dph]


id: GO:0060714
name: labyrinthine layer formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph]


id: GO:0060715
name: syncytiotrophoblast cell differentiation involved in labyrinthine layer development
namespace: biological_process
def:
  "The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta." [GOC:dph]


id: GO:0060716
name: labyrinthine layer blood vessel development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph]


id: GO:0060717
name: chorion development
namespace: biological_process
def:
  "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph]


id: GO:0060718
name: chorionic trophoblast cell differentiation
namespace: biological_process
def:
  "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341]


id: GO:0060719
name: chorionic trophoblast cell development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph]


id: GO:0060720
name: spongiotrophoblast cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer." [GOC:dph]


id: GO:0060721
name: regulation of spongiotrophoblast cell proliferation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation." [GOC:dph]


id: GO:0060722
name: cell proliferation involved in embryonic placenta development
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph]


id: GO:0060723
name: regulation of cell proliferation involved in embryonic placenta development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph]


id: GO:0060724
name: coreceptor activity involved in epidermal growth factor receptor signaling pathway
namespace: molecular_function
def:
  "Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway." [GOC:dph, GOC:tb]


id: GO:0060725
name: regulation of coreceptor activity
namespace: biological_process
def:
  "Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity." [GOC:dph, GOC:tb]


id: GO:0060726
name: regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb]


id: GO:0060727
namespace: biological_process
name:
  positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

def:
  "Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb]


id: GO:0060728
namespace: biological_process
name:
  negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

def:
  "Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb]


id: GO:0060729
name: intestinal epithelial structure maintenance
namespace: biological_process
def:
  "A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060730
name: regulation of intestinal epithelial structure maintenance
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060731
name: positive regulation of intestinal epithelial structure maintenance
namespace: biological_process
def:
  "Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:dph, GOC:tb]


id: GO:0060732
name: positive regulation of inositol phosphate biosynthetic process
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:dph, GOC:tb]


id: GO:0060733
name: regulation of eIF2 alpha phosphorylation by amino acid starvation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation." [GOC:dph, GOC:tb]


id: GO:0060734
name: regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress." [GOC:dph, GOC:tb]


id: GO:0060735
name: regulation of eIF2 alpha phosphorylation by dsRNA
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA." [GOC:dph, GOC:tb]


id: GO:0060736
name: prostate gland growth
namespace: biological_process
def:
  "The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state." [GOC:dph]


id: GO:0060737
name: prostate gland morphogenetic growth
namespace: biological_process
def:
  "The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form." [GOC:dph]


id: GO:0060738
name: epithelial-mesenchymal signaling involved in prostate gland development
namespace: biological_process
def:
  "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060739
name: mesenchymal-epithelial cell signaling involved in prostate gland development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060740
name: prostate gland epithelium morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph]


id: GO:0060741
name: prostate gland stromal morphogenesis
namespace: biological_process
def:
  "The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland." [GOC:dph]


id: GO:0060742
name: epithelial cell differentiation involved in prostate gland development
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland." [GOC:dph]


id: GO:0060743
name: epithelial cell maturation involved in prostate gland development
namespace: biological_process
def:
  "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph]


id: GO:0060744
name: mammary gland branching involved in thelarche
namespace: biological_process
def:
  "The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, PMID:19261859]


id: GO:0060745
name: mammary gland branching involved in pregnancy
namespace: biological_process
def:
  "The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy." [GOC:dph, PMID:19261859]


id: GO:0060747
name: oral incubation
namespace: biological_process
def:
  "A parental behavior in which fertilized eggs are taken into the mouth and held until hatching." [GOC:dph]


id: GO:0060748
name: tertiary branching involved in mammary gland duct morphogenesis
namespace: biological_process
def:
  "The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy." [GOC:dph, PMID:18614704]


id: GO:0060749
name: mammary gland alveolus development
namespace: biological_process
def:
  "The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland." [GOC:dph]


id: GO:0060750
name: epithelial cell proliferation involved in mammary gland duct elongation
namespace: biological_process
def:
  "The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth." [GOC:dph]


id: GO:0060752
name: intestinal phytosterol absorption
namespace: biological_process
def:
  "Any process in which phytosterols are taken up from the contents of the intestine." [GOC:dph, GOC:tb]


id: GO:0060753
name: regulation of mast cell chemotaxis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb]


id: GO:0060754
name: positive regulation of mast cell chemotaxis
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb]


id: GO:0060755
name: negative regulation of mast cell chemotaxis
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb]


id: GO:0060758
name: foraging behavior by probing substrate
namespace: biological_process
def:
  "Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food." [GOC:dph, GOC:tb]


id: GO:0060759
name: regulation of response to cytokine stimulus
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060760
name: positive regulation of response to cytokine stimulus
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060761
name: negative regulation of response to cytokine stimulus
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb]


id: GO:0060762
name: regulation of branching involved in mammary gland duct morphogenesis
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis." [GOC:dph]


id: GO:0060763
name: mammary duct terminal end bud growth
namespace: biological_process
def:
  "The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty." [GOC:dph, PMID:10804170]


id: GO:0060764
name: cell-cell signaling involved in mammary gland development
namespace: biological_process
def:
  "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure." [GOC:dph]


id: GO:0060765
name: regulation of androgen receptor signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway." [GOC:dph]


id: GO:0060766
name: negative regulation of androgen receptor signaling pathway
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway." [GOC:dph]


id: GO:0060767
name: epithelial cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060768
name: regulation of epithelial cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060769
name: positive regulation of epithelial cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060770
name: negative regulation of epithelial cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph]


id: GO:0060771
name: phyllotactic patterning
namespace: biological_process
def:
  "The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060772
name: leaf phyllotactic patterning
namespace: biological_process
def:
  "The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060773
name: flower phyllotactic patterning
namespace: biological_process
def:
  "The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060774
name: auxin mediated signaling pathway involved in phyllotactic patterning
namespace: biological_process
def:
  "The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060775
name: planar cell polarity pathway involved in gastrula mediolateral intercalation
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060776
name: simple leaf morphogenesis
namespace: biological_process
def:
  "The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060777
name: compound leaf morphogenesis
namespace: biological_process
def:
  "The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060778
name: primary leaflet morphogenesis
namespace: biological_process
def:
  "The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060779
name: secondary leaflet morphogenesis
namespace: biological_process
def:
  "The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060780
name: intercalary leaflet morphogenesis
namespace: biological_process
def:
  "The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060781
name: mesenchymal cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time." [GOC:dph, PMID:12221011]


id: GO:0060782
name: regulation of mesenchymal cell proliferation involved in prostate gland development
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, PMID:12221011]


id: GO:0060783
name: mesenchymal smoothened signaling pathway involved in prostate gland development
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development." [PMID:12221011]


id: GO:0060784
name: regulation of cell proliferation involved in tissue homeostasis
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue." [GOC:dph]


id: GO:0060785
name: regulation of apoptosis involved in tissue homeostasis
namespace: biological_process
def:
  "Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue." [GOC:dph]


id: GO:0060786
name: regulation of cell differentiation involved in tissue homeostasis
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue." [GOC:dph]


id: GO:0060787
namespace: biological_process
name:
  positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

def:
  "Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060788
name: ectodermal placode formation
namespace: biological_process
def:
  "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060789
name: hair follicle placode formation
namespace: biological_process
def:
  "The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060790
name: tooth placode formation
namespace: biological_process
def:
  "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060791
name: sebaceous gland placode formation
namespace: biological_process
def:
  "The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060792
name: sweat gland development
namespace: biological_process
def:
  "The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060793
name: sweat gland placode formation
namespace: biological_process
def:
  "The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060794
name: leaflet morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the leaflet are generated and organized." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060795
name: cell fate commitment involved in formation of primary germ layer
namespace: biological_process
def:
  "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060796
name: regulation of transcription involved in primary germ layer cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060797
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment

def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060798
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification

def:
  "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060799
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification

def:
  "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060800
name: regulation of cell differentiation involved in embryonic placenta development
namespace: biological_process
def:
  "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060801
namespace: biological_process
name:
  negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway

def:
  "The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060802
namespace: biological_process
name:
  epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

def:
  "Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060803
name: BMP signaling pathway involved in mesodermal cell fate specification
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060804
name: positive regulation of Wnt signaling pathway by BMP signaling pathway
namespace: biological_process
def:
  "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060805
namespace: biological_process
name:
  negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter

def:
  "Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060806
name: negative regulation of cell differentiation involved in embryonic placenta development
namespace: biological_process
def:
  "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060807
namespace: biological_process
name:
  regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification

def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060808
name: positive regulation of mesodermal to mesenchymal transition involved in gastrulation
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060809
name: mesodermal to mesenchymal transition involved in gastrulation
namespace: biological_process
def:
  "The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060810
name: intracellular mRNA localization involved in pattern specification process
namespace: biological_process
def:
  "Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060811
name: intracellular mRNA localization involved in anterior/posterior axis specification
namespace: biological_process
def:
  "Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060812
name: orthodenticle mRNA localization
namespace: biological_process
def:
  "Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060813
name: anterior mRNA localization involved in anterior/posterior axis specification
namespace: biological_process
def:
  "Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060814
name: posterior mRNA localization involved in anterior/posterior axis specification
namespace: biological_process
def:
  "Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060815
name: regulation of translation involved in anterior/posterior axis specification
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060816
name: random inactivation of X chromosome
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060817
name: inactivation of paternal X chromosome
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060818
name: inactivation of paternal X chromosome by genetic imprinting
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060819
name: inactivation of X chromosome by genetic imprinting
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060820
name: inactivation of X chromosome by heterochromatin assembly
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060821
name: inactivation of X chromosome by DNA methylation
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060822
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification

def:
  "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060823
name: canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060824
namespace: biological_process
name:
  retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation

def:
  "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060825
namespace: biological_process
name:
  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation

def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060826
namespace: biological_process
name:
  transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation

def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060827
namespace: biological_process
name:
  regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

def:
  "Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060828
name: regulation of canonical Wnt signaling pathway
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060829
namespace: biological_process
name:
  negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

def:
  "Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060830
name: ciliary receptor clustering involved in smoothened signaling pathway
namespace: biological_process
def:
  "Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060831
name: smoothened signaling pathway involved in dorsal/ventral neural tube patterning
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060832
name: oocyte animal/vegetal axis specification
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060833
name: Wnt signaling pathway involved in animal/vegetal axis specification
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060834
name: oral/aboral axis specification
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060835
namespace: biological_process
name:
  transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification

def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060836
name: lymphatic endothelial cell differentiation
namespace: biological_process
def:
  "The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060837
name: blood vessel endothelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060838
name: lymphatic endothelial cell fate commitment
namespace: biological_process
def:
  "The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060839
name: endothelial cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060840
name: artery development
namespace: biological_process
def:
  "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060841
name: venous blood vessel development
namespace: biological_process
def:
  "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060842
name: arterial endothelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060843
name: venous endothelial cell differentiation
namespace: biological_process
def:
  "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060844
name: arterial endothelial cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060845
name: venous endothelial cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060846
name: blood vessel endothelial cell fate commitment
namespace: biological_process
def:
  "The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060847
name: endothelial cell fate specification
namespace: biological_process
def:
  "The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060848
name: endothelial cell fate determination
namespace: biological_process
def:
  "A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060849
name: regulation of transcription involved in lymphatic endothelial cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060850
name: regulation of transcription involved in cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060851
namespace: biological_process
name:
  vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment

def:
  "The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060852
name: regulation of transcription involved in venous endothelial cell fate commitment
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060853
name: Notch signaling pathway involved in arterial endothelial cell fate commitment
namespace: biological_process
def:
  "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060854
name: patterning of lymph vessels
namespace: biological_process
def:
  "The process that regulates the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060855
name: venous endothelial cell migration involved in lymph vessel development
namespace: biological_process
def:
  "The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060856
name: establishment of blood-brain barrier
namespace: biological_process
def:
  "Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:dph, GOC:sart]


id: GO:0060857
name: establishment of glial blood-brain barrier
namespace: biological_process
def:
  "Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:dph, GOC:sart]


id: GO:0060858
name: vesicle-mediated transport involved in floral organ abscission
namespace: biological_process
def:
  "The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060859
name: regulation of vesicle-mediated transport involved in floral organ abscission
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060860
name: regulation of floral organ abscission
namespace: biological_process
def:
  "Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060861
name: positive regulation of floral organ abscission
namespace: biological_process
def:
  "Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060862
name: negative regulation of floral organ abscission
namespace: biological_process
def:
  "Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060863
name: regulation of floral organ abscission by signal transduction
namespace: biological_process
def:
  "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060864
name: positive regulation of floral organ abscission by small GTPase mediated signal transduction
namespace: biological_process
def:
  "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060865
namespace: biological_process
name:
  negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway

def:
  "The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060868
namespace: biological_process
name:
  regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction

def:
  "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060869
namespace: biological_process
name:
  transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission

def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:signaling, GOC:tb]


id: GO:0060870
name: cell wall disassembly involved in floral organ abscission
namespace: biological_process
def:
  "A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060872
name: semicircular canal development
namespace: biological_process
def:
  "The progression of the semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060873
name: anterior semicircular canal development
namespace: biological_process
def:
  "The progession of the anterior semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060874
name: posterior semicircular canal development
namespace: biological_process
def:
  "The progession of the posterior semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060875
name: lateral semicircular canal development
namespace: biological_process
def:
  "The progession of the lateral semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060876
name: semicircular canal formation
namespace: biological_process
def:
  "The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060877
name: regionalization involved in semicircular canal formation
namespace: biological_process
def:
  "The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060878
name: pouch outgrowth involved in semicircular canal formation
namespace: biological_process
def:
  "The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060879
name: semicircular canal fusion
namespace: biological_process
def:
  "Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms ruing the process of semicircular canal formation." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060880
name: cell morphogenesis involved in semicircular canal fusion
namespace: biological_process
def:
  "The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060882
name: basal lamina disassembly involved in semicircular canal fusion
namespace: biological_process
def:
  "A process that results in the breakdown of the basal lamina that contributes to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060883
name: regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication
namespace: biological_process
def:
  "Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basal lamina disassembly involved in semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060884
name: clearance of cells from fusion plate
namespace: biological_process
def:
  "The morphogenetic process in which cells are removed from the inner loop of a semicircular canal." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060885
name: clearance of cells from fusion plate by apoptotic process
namespace: biological_process
def:
  "Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals." [GOC:dph, GOC:mtg_apoptosis, GOC:sdb_2009, GOC:tb]


id: GO:0060886
name: clearance of cells from fusion plate by epithelial to mesenchymal transition
namespace: biological_process
def:
  "The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals." [GOC:dph, GOC:sdb_2009, GOC:tb]


id: GO:0060887
name: limb epidermis development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb]


