# go

id: GO:0007420
name: brain development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955]


id: GO:0007421
name: stomatogastric nervous system development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007422
name: peripheral nervous system development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010]


id: GO:0007423
name: sensory organ development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators]


id: GO:0007424
name: open tracheal system development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:8625828]


id: GO:0007425
name: epithelial cell fate determination, open tracheal system
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11063940]


id: GO:0007426
name: tracheal outgrowth, open tracheal system
namespace: biological_process
def:
  "The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0007427
name: epithelial cell migration, open tracheal system
namespace: biological_process
def:
  "The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]


id: GO:0007428
name: primary branching, open tracheal system
namespace: biological_process
def:
  "Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, http://cmgm.stanford.edu/krasnow/research.html]


id: GO:0007429
name: secondary branching, open tracheal system
namespace: biological_process
def:
  "Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, http://cmgm.stanford.edu/krasnow/research.html]


id: GO:0007430
name: terminal branching, open tracheal system
namespace: biological_process
def:
  "Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster." [GOC:mtg_sensu, http://cmgm.stanford.edu/krasnow/research.html]


id: GO:0007431
name: salivary gland development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity." [GOC:jid, UBERON:0001044]


id: GO:0007432
name: salivary gland boundary specification
namespace: biological_process
def:
  "Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [PMID:11598957]


id: GO:0007433
name: larval salivary gland boundary specification
namespace: biological_process
def:
  "Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [GOC:tb, PMID:11598957]


id: GO:0007434
name: adult salivary gland boundary specification
namespace: biological_process
def:
  "Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [GOC:tb, PMID:11598957]


id: GO:0007435
name: salivary gland morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the salivary gland are generated and organized." [GOC:jid]


id: GO:0007436
name: larval salivary gland morphogenesis
namespace: biological_process
def:
  "The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized." [GOC:jid]


id: GO:0007437
name: adult salivary gland morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the adult salivary gland are generated and organized." [GOC:go_curators]


id: GO:0007438
name: oenocyte development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments." [GOC:bf, PMID:11171397]


id: GO:0007439
name: ectodermal digestive tract development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators]


id: GO:0007440
name: foregut morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid]


id: GO:0007441
name: anterior midgut (ectodermal) morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized." [GOC:go_curators]


id: GO:0007442
name: hindgut morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid]


id: GO:0007443
name: Malpighian tubule morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut." [GOC:bf, ISBN:0582227089]


id: GO:0007444
name: imaginal disc development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)." [GOC:bf, ISBN:0879694238]


id: GO:0007445
name: determination of imaginal disc primordium
namespace: biological_process
def:
  "Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment." [ISBN:0879694238]


id: GO:0007446
name: imaginal disc growth
namespace: biological_process
def:
  "The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:bf, GOC:jid, PMID:10679387]


id: GO:0007447
name: imaginal disc pattern formation
namespace: biological_process
def:
  "The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:dph, GOC:isa_complete, GOC:jid]


id: GO:0007448
name: anterior/posterior pattern specification, imaginal disc
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form." [GOC:bf, ISBN:0879694238]


id: GO:0007449
name: proximal/distal pattern formation, imaginal disc
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed." [GOC:jid, ISBN:0879694238]


id: GO:0007450
name: dorsal/ventral pattern formation, imaginal disc
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed." [GOC:jid, ISBN:0879694238]


id: GO:0007451
name: dorsal/ventral lineage restriction, imaginal disc
namespace: biological_process
def:
  "Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf, PMID:10625531, PMID:9374402]


id: GO:0007453
name: clypeo-labral disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus." [GOC:bf, ISBN:0879694238]


id: GO:0007454
name: labial disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis." [GOC:bf, ISBN:0879694238]


id: GO:0007455
name: eye-antennal disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238]


id: GO:0007458
name: progression of morphogenetic furrow involved in compound eye morphogenesis
namespace: biological_process
def:
  "The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc." [PMID:3076112, PMID:3937883]


id: GO:0007460
name: R8 cell fate commitment
namespace: biological_process
def:
  "The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium." [PMID:3076112, PMID:3937883]


id: GO:0007462
name: R1/R6 cell fate commitment
namespace: biological_process
def:
  "The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883]


id: GO:0007463
name: R2/R5 cell fate commitment
namespace: biological_process
def:
  "The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883]


id: GO:0007464
name: R3/R4 cell fate commitment
namespace: biological_process
def:
  "The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883]


id: GO:0007465
name: R7 cell fate commitment
namespace: biological_process
def:
  "The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium." [PMID:3076112, PMID:3937883]


id: GO:0007468
name: regulation of rhodopsin gene expression
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation." [GOC:dph, GOC:go_curators, GOC:tb]


id: GO:0007469
name: antennal development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli." [http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526]


id: GO:0007470
name: prothoracic disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle." [GOC:bf, ISBN:0879694238]


id: GO:0007471
name: obsolete prothoracic morphogenesis
namespace: biological_process
def:
  "OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized." [GOC:jid]


id: GO:0007472
name: wing disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura." [GOC:bf, ISBN:0879694238]


id: GO:0007473
name: wing disc proximal/distal pattern formation
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing." [GOC:bf]


id: GO:0007474
name: imaginal disc-derived wing vein specification
namespace: biological_process
def:
  "The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified." [GOC:dph, GOC:isa_complete, GOC:mtg_sensu]


id: GO:0007475
name: apposition of dorsal and ventral imaginal disc-derived wing surfaces
namespace: biological_process
def:
  "The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing." [GOC:bf, GOC:mtg_sensu]


id: GO:0007476
name: imaginal disc-derived wing morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu]


id: GO:0007477
name: notum development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007478
name: leg disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura." [GOC:bf, ISBN:0879694238]


id: GO:0007479
name: leg disc proximal/distal pattern formation
namespace: biological_process
def:
  "The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg." [GOC:bf]


id: GO:0007480
name: imaginal disc-derived leg morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238]


id: GO:0007481
name: haltere disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum." [GOC:bf, ISBN:0879694238]


id: GO:0007482
name: haltere development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings." [GOC:jid, http://www.earthlife.net]


id: GO:0007483
name: genital disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut." [GOC:bf, ISBN:0879694238]


id: GO:0007484
name: imaginal disc-derived genitalia development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu]


id: GO:0007485
name: imaginal disc-derived male genitalia development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu]


id: GO:0007486
name: imaginal disc-derived female genitalia development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu]


id: GO:0007487
name: analia development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster." [GOC:ai, GOC:mtg_sensu]


id: GO:0007488
name: histoblast morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen." [GOC:bf, ISBN:0879694238]


id: GO:0007489
name: maintenance of imaginal histoblast diploidy
namespace: biological_process
def:
  "The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells." [GOC:bf, ISBN:0879694238]


id: GO:0007490
name: tergite morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment." [GOC:jid, http://www.earthlife.net]


id: GO:0007491
name: sternite morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment." [GOC:jid, http://www.earthlife.net]


id: GO:0007492
name: endoderm development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb]


id: GO:0007493
name: endodermal cell fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, ISBN:0878932437]


id: GO:0007494
name: midgut development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045]


id: GO:0007495
name: visceral mesoderm-endoderm interaction involved in midgut development
namespace: biological_process
def:
  "The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut." [GOC:dph, GOC:isa_complete]


id: GO:0007496
name: anterior midgut development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007497
name: posterior midgut development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure." [GOC:go_curators]


id: GO:0007498
name: mesoderm development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb]


id: GO:0007499
name: ectoderm and mesoderm interaction
namespace: biological_process
def:
  "A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm." [GOC:isa_complete]


id: GO:0007500
name: mesodermal cell fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, ISBN:0878932437]


id: GO:0007501
name: mesodermal cell fate specification
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators]


id: GO:0007502
name: digestive tract mesoderm development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism." [GOC:ai]


id: GO:0007503
name: fat body development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism." [ISBN:0582227089]


id: GO:0007504
name: larval fat body development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life." [GOC:bf, ISBN:0879694238]


id: GO:0007505
name: adult fat body development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body." [GOC:bf, ISBN:0879694238]


id: GO:0007506
name: gonadal mesoderm development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai]


id: GO:0007507
name: heart development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948]


id: GO:0007508
name: larval heart development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper." [GOC:bf, ISBN:08779694238]


id: GO:0007509
name: mesoderm migration involved in gastrulation
namespace: biological_process
def:
  "The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism." [GOC:isa_complete, GOC:sat]


id: GO:0007510
name: cardioblast cell fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators]


id: GO:0007512
name: adult heart development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure." [GOC:bf]


id: GO:0007515
name: obsolete lymph gland development
namespace: biological_process
def:
  "OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system." [GOC:jid]


id: GO:0007516
name: hemocyte development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu]


id: GO:0007517
name: muscle organ development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732]


id: GO:0007518
name: myoblast fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators]


id: GO:0007519
name: skeletal muscle tissue development
namespace: biological_process
def:
  "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle]


id: GO:0007520
name: myoblast fusion
namespace: biological_process
def:
  "A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle]


id: GO:0007521
name: muscle cell fate determination
namespace: biological_process
def:
  "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed." [CL:0000187, GOC:go_curators]


id: GO:0007522
name: visceral muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure." [GOC:go_curators]


id: GO:0007523
name: larval visceral muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007524
name: adult visceral muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007525
name: somatic muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle." [GOC:jid, GOC:mtg_muscle]


id: GO:0007526
name: larval somatic muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007527
name: adult somatic muscle development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure." [GOC:jid]


id: GO:0007528
name: neuromuscular junction development
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013]


id: GO:0007529
name: establishment of synaptic specificity at neuromuscular junction
namespace: biological_process
def:
  "The biological process in which a synapse between a motor neuron and a muscle is initially formed." [GOC:isa_complete]


id: GO:0007530
name: sex determination
namespace: biological_process
def:
  "Any process that establishes and transmits the specification of sexual status of an individual organism." [ISBN:0198506732]


id: GO:0007531
name: mating type determination
namespace: biological_process
def:
  "Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms." [http://www.biology-text.com/]


id: GO:0007532
name: regulation of mating-type specific transcription, DNA-templated
namespace: biological_process
def:
  "Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]


id: GO:0007533
name: mating type switching
namespace: biological_process
def:
  "The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [PMID:9928492]


id: GO:0007534
name: gene conversion at mating-type locus
namespace: biological_process
def:
  "The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged." [GOC:elh, PMID:9928492]


id: GO:0007535
name: donor selection
namespace: biological_process
def:
  "The process that determines which donor locus a cell uses, in preference to another, in mating type switching." [GOC:mah, PMID:9928492]


id: GO:0007536
name: activation of recombination (HML)
namespace: biological_process
def:
  "The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492]


id: GO:0007537
name: inactivation of recombination (HML)
namespace: biological_process
def:
  "The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492]


id: GO:0007538
name: primary sex determination
namespace: biological_process
def:
  "The sex determination process that results in the initial specification of sexual status of an individual organism." [GOC:mah]


id: GO:0007539
name: primary sex determination, soma
namespace: biological_process
def:
  "The transmission of information about sexual status from the initial, general, determination to signals specific to the soma." [GOC:ems]


id: GO:0007540
name: sex determination, establishment of X:A ratio
namespace: biological_process
def:
  "The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it." [GOC:isa_complete]


id: GO:0007541
name: sex determination, primary response to X:A ratio
namespace: biological_process
def:
  "The developmental process in which an organism interprets its X to autosomal chromosomal complement." [GOC:isa_complete]


id: GO:0007542
name: primary sex determination, germ-line
namespace: biological_process
def:
  "The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line." [GOC:ems]


id: GO:0007543
name: sex determination, somatic-gonadal interaction
namespace: biological_process
def:
  "The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism." [GOC:isa_complete]


id: GO:0007545
name: processes downstream of sex determination signal
namespace: biological_process
def:
  "The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways." [GOC:mah]


id: GO:0007546
name: somatic processes downstream of sex determination signal
namespace: biological_process
def:
  "The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways." [GOC:ems]


id: GO:0007547
name: germ-line processes downstream of sex determination signal
namespace: biological_process
def:
  "The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways." [GOC:ems]


id: GO:0007549
name: dosage compensation
namespace: biological_process
def:
  "Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes." [GOC:ems, ISBN:0140512888, PMID:11498577]


id: GO:0007552
name: metamorphosis
namespace: biological_process
def:
  "A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster." [GOC:sensu, ISBN:0198506732, ISBN:0721662544]


id: GO:0007553
name: regulation of ecdysteroid metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732]


id: GO:0007554
name: regulation of ecdysteroid biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators]


id: GO:0007555
name: regulation of ecdysteroid secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell." [GOC:go_curators]


id: GO:0007556
name: regulation of juvenile hormone metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators]


id: GO:0007557
name: regulation of juvenile hormone biosynthetic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators]


id: GO:0007558
name: regulation of juvenile hormone secretion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of juvenile hormone secretion." [GOC:go_curators]


id: GO:0007559
name: histolysis
namespace: biological_process
def:
  "The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue." [GOC:dph, GOC:ma]


id: GO:0007560
name: imaginal disc morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:jid]


id: GO:0007561
name: imaginal disc eversion
namespace: biological_process
def:
  "The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis." [PMID:11494317]


id: GO:0007563
name: regulation of eclosion
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg." [GOC:go_curators, ISBN:0198600461]


id: GO:0007564
name: regulation of chitin-based cuticle tanning
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning." [GOC:go_curators, GOC:jid, GOC:mtg_sensu]


id: GO:0007565
name: female pregnancy
namespace: biological_process
def:
  "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825]


id: GO:0007567
name: parturition
namespace: biological_process
def:
  "The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs." [ISBN:0198506732]


id: GO:0007568
name: aging
namespace: biological_process
def:
  "A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators]


id: GO:0007569
name: cell aging
namespace: biological_process
def:
  "An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469)." [GOC:PO_curators]


id: GO:0007571
name: age-dependent general metabolic decline
namespace: biological_process
def:
  "A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis." [GOC:jh, GOC:mah, PMID:9891807]


id: GO:0007574
name: obsolete cell aging (sensu Saccharomyces)
namespace: biological_process
def:
  "OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell." [GOC:sgd_curators]


id: GO:0007576
name: nucleolar fragmentation
namespace: biological_process
def:
  "The cell aging process that results in the nucleolus breaking down into fragments." [GOC:mah, PMID:9271578]


id: GO:0007577
name: obsolete autophagic death (sensu Saccharomyces)
namespace: biological_process
def:
  "OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA." [GOC:sgd_curators]


id: GO:0007578
name: obsolete aging dependent sterility (sensu Saccharomyces)
namespace: biological_process
def:
  "OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes." [GOC:sgd_curators]


id: GO:0007580
name: extrachromosomal circular DNA accumulation involved in cell aging
namespace: biological_process
def:
  "Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication." [GOC:jh, PMID:9891807]


id: GO:0007584
name: response to nutrient
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus." [GOC:go_curators]


id: GO:0007585
name: respiratory gaseous exchange
namespace: biological_process
def:
  "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732]


id: GO:0007586
name: digestion
namespace: biological_process
def:
  "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732]


id: GO:0007588
name: excretion
namespace: biological_process
def:
  "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023]


id: GO:0007589
name: body fluid secretion
namespace: biological_process
def:
  "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb]


id: GO:0007590
name: obsolete fat body metabolic process (sensu Insecta)
namespace: biological_process
def:
  "OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557)." [GOC:go_curators, ISBN:0198506732]


id: GO:0007591
name: molting cycle, chitin-based cuticle
namespace: biological_process
def:
  "The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster." [GOC:jl, GOC:mtg_sensu]


id: GO:0007592
name: obsolete protein-based cuticle development
namespace: biological_process
def:
  "OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans." [GOC:ems, GOC:mtg_sensu]


id: GO:0007594
name: puparial adhesion
namespace: biological_process
def:
  "The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation." [GOC:ma]


id: GO:0007596
name: blood coagulation
namespace: biological_process
def:
  "The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers." [http://www.graylab.ac.uk/omd/, ISBN:0198506732]


id: GO:0007597
name: blood coagulation, intrinsic pathway
namespace: biological_process
def:
  "A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X." [GOC:add, GOC:mah, GOC:pde]


id: GO:0007598
name: blood coagulation, extrinsic pathway
namespace: biological_process
def:
  "A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X." [GOC:add, GOC:mah, GOC:pde]


id: GO:0007599
name: hemostasis
namespace: biological_process
def:
  "The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part." [ISBN:0198506732]


id: GO:0007600
name: sensory perception
namespace: biological_process
def:
  "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph]


id: GO:0007601
name: visual perception
namespace: biological_process
def:
  "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai]


id: GO:0007602
name: phototransduction
namespace: biological_process
def:
  "The sequence of reactions within a cell required to convert absorbed photons into a molecular signal." [GOC:go_curators]


id: GO:0007603
name: phototransduction, visible light
namespace: biological_process
def:
  "The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732]


id: GO:0007604
name: phototransduction, UV
namespace: biological_process
def:
  "The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers." [GOC:go_curators, ISBN:0198506732]


id: GO:0007605
name: sensory perception of sound
namespace: biological_process
def:
  "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai]


id: GO:0007606
name: sensory perception of chemical stimulus
namespace: biological_process
def:
  "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai]


id: GO:0007607
name: obsolete taste perception
namespace: biological_process
def:
  "OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal." [GOC:jl, ISBN:0395825172]


id: GO:0007608
name: sensory perception of smell
namespace: biological_process
def:
  "The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process." [GOC:ai, http://www.onelook.com/]


id: GO:0007610
name: behavior
namespace: biological_process
def:
  "The internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973]


id: GO:0007611
name: learning or memory
namespace: biological_process
def:
  "The acquisition and processing of information and/or the storage and retrieval of this information over time." [GOC:jid, PMID:8938125]


id: GO:0007612
name: learning
namespace: biological_process
def:
  "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience." [ISBN:0582227089, ISBN:0721662544]


id: GO:0007613
name: memory
namespace: biological_process
def:
  "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." [GOC:curators, http://www.onelook.com/, ISBN:0582227089]


id: GO:0007614
name: short-term memory
namespace: biological_process
def:
  "The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089]


id: GO:0007615
name: anesthesia-resistant memory
namespace: biological_process
def:
  "The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis." [PMID:15143285, PMID:17088531]


id: GO:0007616
name: long-term memory
namespace: biological_process
def:
  "The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089]


id: GO:0007617
name: mating behavior
namespace: biological_process
def:
  "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph]


id: GO:0007618
name: mating
namespace: biological_process
def:
  "The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes." [GOC:jl, ISBN:0387520546]


id: GO:0007619
name: courtship behavior
namespace: biological_process
def:
  "The behavioral interactions between organisms for the purpose of attracting sexual partners." [GOC:ai, GOC:dph]


id: GO:0007620
name: copulation
namespace: biological_process
def:
  "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544]


id: GO:0007621
name: negative regulation of female receptivity
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the receptiveness of a female to male advances." [GOC:bf, PMID:11092827]


id: GO:0007623
name: circadian rhythm
namespace: biological_process
def:
  "Any biological process in an organism that recurs with a regularity of approximately 24 hours." [GOC:bf, GOC:go_curators]


id: GO:0007624
name: ultradian rhythm
namespace: biological_process
def:
  "The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours." [GOC:jl, PMID:19708721]


id: GO:0007625
name: grooming behavior
namespace: biological_process
def:
  "The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites." [GOC:jl, GOC:pr]


id: GO:0007626
name: locomotory behavior
namespace: biological_process
def:
  "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph]


id: GO:0007627
name: obsolete larval behavior (sensu Insecta)
namespace: biological_process
def:
  "OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects." [GOC:ai, GOC:jid]


id: GO:0007628
name: adult walking behavior
namespace: biological_process
def:
  "The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg." [GOC:jid, GOC:pr, ISBN:0198606907]


id: GO:0007629
name: flight behavior
namespace: biological_process
def:
  "The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air." [GOC:jid, ISBN:0198606907]


id: GO:0007630
name: jump response
namespace: biological_process
def:
  "The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus." [GOC:jid, ISBN:0198606907]


id: GO:0007633
name: pattern orientation
namespace: biological_process
def:
  "The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes." [GOC:jid, PMID:9933535]


id: GO:0007634
name: optokinetic behavior
namespace: biological_process
def:
  "The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus." [GOC:jid, GOC:pr, http://www.mercksource.com]


id: GO:0007636
name: chemosensory jump behavior
namespace: biological_process
def:
  "The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance." [GOC:jid]


id: GO:0007637
name: proboscis extension reflex
namespace: biological_process
def:
  "The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a sugar stimulus." [FB:FBrf0044924, GOC:jid]


id: GO:0007639
name: homeostasis of number of meristem cells
namespace: biological_process
def:
  "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem." [GOC:isa_complete]


id: GO:0008002
name: lamina lucida
namespace: cellular_component
def:
  "The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina." [ISBN:0815316194]


id: GO:0008003
name: lamina densa
namespace: cellular_component
def:
  "The electron-dense layer of the basal lamina; lies just below the lamina lucida." [ISBN:0815316194]


id: GO:0008004
name: lamina reticularis
namespace: cellular_component
def:
  "A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue." [ISBN:0815316194]


id: GO:0008009
name: chemokine activity
namespace: molecular_function
def:
  "The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, http://en.wikipedia.org/wiki/Chemokine, http://www.copewithcytokines.de/cope.cgi?key=Cytokines, PMID:12183377]


id: GO:0008010
name: structural constituent of chitin-based larval cuticle
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu]


id: GO:0008011
name: structural constituent of pupal chitin-based cuticle
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu]


id: GO:0008012
name: structural constituent of adult chitin-based cuticle
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu]


id: GO:0008014
name: obsolete calcium-dependent cell adhesion molecule activity
namespace: molecular_function
def:
  "OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions." [ISBN:0198506732]


id: GO:0008015
name: blood circulation
namespace: biological_process
def:
  "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825]


id: GO:0008016
name: regulation of heart contraction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb]


id: GO:0008017
name: microtubule binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers." [GOC:krc]


id: GO:0008020
name: G-protein coupled photoreceptor activity
namespace: molecular_function
def:
  "Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph, ISBN:0198506732]


id: GO:0008021
name: synaptic vesicle
namespace: cellular_component
def:
  "A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." [PMID:10099709, PMID:12563290]


id: GO:0008022
name: protein C-terminus binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue." [ISBN:0198506732]


id: GO:0008023
name: transcription elongation factor complex
namespace: cellular_component
def:
  "Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation." [GOC:jl]


id: GO:0008024
name: positive transcription elongation factor complex b
namespace: cellular_component
def:
  "A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains cyclin T and a cyclin-dependent protein kinase catalytic subunit." [GOC:bhm, PMID:10766736, PMID:16721054, PMID:17079683, PMID:19328067, PMID:7759473]


id: GO:0008025
name: obsolete diazepam binding inhibitor activity
namespace: molecular_function
def:
  "OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters." [ISBN:0198506732, PMID:11883709]


id: GO:0008026
name: ATP-dependent helicase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix." [EC:3.6.1.3, GOC:jl]


id: GO:0008028
name: monocarboxylic acid transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai]


id: GO:0008029
name: pentraxin receptor activity
namespace: molecular_function
def:
  "Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149]


id: GO:0008030
name: neuronal pentraxin receptor activity
namespace: molecular_function
def:
  "Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling, PMID:18840757]


id: GO:0008031
name: eclosion hormone activity
namespace: molecular_function
def:
  "The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis." [GOC:mah, ISBN:0198506732]


id: GO:0008033
name: tRNA processing
namespace: biological_process
def:
  "The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group." [GOC:jl, PMID:12533506]


id: GO:0008034
name: obsolete lipoprotein binding
namespace: molecular_function
def:
  "OBSOLETE. Interacting selectively and non-covalently with any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:jl, ISBN:0198506732]


id: GO:0008035
name: high-density lipoprotein particle binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE." [GOC:mah]


id: GO:0008036
name: diuretic hormone receptor activity
namespace: molecular_function
def:
  "Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity." [GOC:ai, GOC:signaling]


id: GO:0008038
name: neuron recognition
namespace: biological_process
def:
  "The process in which a neuronal cell in a multicellular organism interprets its surroundings." [GOC:go_curators]


id: GO:0008039
name: synaptic target recognition
namespace: biological_process
def:
  "The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses." [GOC:mah, ISBN:0878932437]


id: GO:0008042
name: obsolete iron-sulfur electron transfer carrier
namespace: molecular_function
def:
  "OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system." [GOC:kd]


id: GO:0008043
name: intracellular ferritin complex
namespace: cellular_component
def:
  "A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains." [GOC:jl, GOC:mah, PMID:19154717]


id: GO:0008044
name: obsolete adult behavior (sensu Insecta)
namespace: biological_process
def:
  "OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects." [GOC:bf, GOC:jid]


id: GO:0008045
name: motor neuron axon guidance
namespace: biological_process
def:
  "The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues." [CL:0000100, GOC:pr, ISBN:0878932437]


id: GO:0008046
name: axon guidance receptor activity
namespace: molecular_function
def:
  "Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance." [GOC:dph, GOC:signaling, GOC:tb, PMID:15107857, PMID:15339666]


id: GO:0008048
name: calcium sensitive guanylate cyclase activator activity
namespace: molecular_function
def:
  "Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration." [GOC:mah]


id: GO:0008049
name: male courtship behavior
namespace: biological_process
def:
  "The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, GOC:pr]


id: GO:0008052
name: sensory organ boundary specification
namespace: biological_process
def:
  "The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained." [GO_REF:0000021, GOC:mtg_15jun06]


id: GO:0008054
name: negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions via the negative regulation of a cyclin-dependent kinase." [GOC:mah, PMID:15840442]


id: GO:0008055
name: ocellus pigment biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates." [GOC:ai, PMID:15176085, PMID:18421706]


id: GO:0008056
name: ocellus development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects." [http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540]


id: GO:0008057
name: eye pigment granule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye." [PMID:9303295]


id: GO:0008058
name: ocellus pigment granule organization
namespace: biological_process
def:
  "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm]


id: GO:0008061
name: chitin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732]


id: GO:0008062
name: eclosion rhythm
namespace: biological_process
def:
  "The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn." [PMID:11715043]


id: GO:0008063
name: Toll signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:11135568, PMID:19126860]


id: GO:0008064
name: regulation of actin polymerization or depolymerization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah]


id: GO:0008065
name: establishment of blood-nerve barrier
namespace: biological_process
def:
  "The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier." [GOC:dgh]


id: GO:0008066
name: glutamate receptor activity
namespace: molecular_function
def:
  "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling]


id: GO:0008067
name: obsolete metabotropic glutamate, GABA-B-like receptor activity
namespace: molecular_function
def:
  "OBSOLETE. A G-protein coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor." [GOC:dph, GOC:mah, GOC:tb, IUPHAR_GPCR:1285]


id: GO:0008068
name: extracellular-glutamate-gated chloride channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729]


id: GO:0008069
name: dorsal/ventral axis specification, ovarian follicular epithelium
namespace: biological_process
def:
  "Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:dph, GOC:mtg_sensu, GOC:tb]


id: GO:0008070
name: maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded
namespace: biological_process
def:
  "Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line." [GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008071
name: maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded
namespace: biological_process
def:
  "Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008073
name: ornithine decarboxylase inhibitor activity
namespace: molecular_function
def:
  "The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase." [GOC:jl]


id: GO:0008076
name: voltage-gated potassium channel complex
namespace: cellular_component
def:
  "A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential." [GOC:mah]


id: GO:0008078
name: mesodermal cell migration
namespace: biological_process
def:
  "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047]


id: GO:0008080
name: N-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule." [GOC:ai]


id: GO:0008081
name: phosphoric diester hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group." [EC:3.1.4, GOC:curators]


id: GO:0008083
name: growth factor activity
namespace: molecular_function
def:
  "The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation." [ISBN:0815316194]


id: GO:0008084
name: imaginal disc growth factor receptor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with an imaginal disc growth factor receptor." [GOC:mah]


id: GO:0008086
name: light-activated voltage-gated calcium channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport]


id: GO:0008087
name: light-activated voltage-gated calcium channel complex
namespace: cellular_component
def:
  "A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus." [GOC:mah, PMID:9223679]


id: GO:0008088
name: axo-dendritic transport
namespace: biological_process
def:
  "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194]


id: GO:0008089
name: anterograde axonal transport
namespace: biological_process
def:
  "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." [ISBN:0815316194]


id: GO:0008090
name: retrograde axonal transport
namespace: biological_process
def:
  "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194]


id: GO:0008091
name: spectrin
namespace: cellular_component
def:
  "Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins." [GOC:curators, ISBN:0815316194]


id: GO:0008092
name: cytoskeletal protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)." [GOC:mah]


id: GO:0008093
name: cytoskeletal adaptor activity
namespace: molecular_function
def:
  "The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07]


id: GO:0008094
name: DNA-dependent ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction." [EC:3.6.1.3, GOC:jl]


id: GO:0008096
name: juvenile hormone epoxide hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol." [GOC:mah, PMID:8396141]


id: GO:0008097
name: 5S rRNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome." [GOC:jl, ISBN:0321000382]


id: GO:0008098
name: 5S rRNA primary transcript binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with the unprocessed 5S ribosomal RNA transcript." [GOC:jl]


id: GO:0008100
name: obsolete lipophorin
namespace: molecular_function
def:
  "OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects." [ISBN:0198506732]


id: GO:0008101
name: decapentaplegic signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of decapentaplegic (dpp) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:sart, PMID:17428827]


id: GO:0008103
name: oocyte microtubule cytoskeleton polarization
namespace: biological_process
def:
  "Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11807042]


id: GO:0008105
name: asymmetric protein localization
namespace: biological_process
def:
  "Any process in which a protein is transported to, or maintained in, a specific location such that it is distributed asymmetrically." [GOC:ma]


id: GO:0008107
name: galactoside 2-alpha-L-fucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R." [EC:2.4.1.69]


id: GO:0008108
name: UDP-glucose:hexose-1-phosphate uridylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose." [EC:2.7.7.12, RHEA:13992]


id: GO:0008109
name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.150]


id: GO:0008110
name: L-histidine:2-oxoglutarate aminotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate." [EC:2.6.1.38, RHEA:16568]


id: GO:0008112
name: nicotinamide N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine." [EC:2.1.1.1, RHEA:23887]


id: GO:0008113
name: peptide-methionine (S)-S-oxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.8.4.11, GOC:mah, GOC:vw, PMID:11169920]


id: GO:0008114
name: phosphogluconate 2-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH." [EC:1.1.1.43]


id: GO:0008115
name: sarcosine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2)." [EC:1.5.3.1, RHEA:13316]


id: GO:0008117
name: sphinganine-1-phosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde." [EC:4.1.2.27]


id: GO:0008118
name: N-acetyllactosaminide alpha-2,3-sialyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein." [EC:2.4.99.6]


id: GO:0008119
name: thiopurine S-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether." [EC:2.1.1.67]


id: GO:0008120
name: ceramide glucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine." [EC:2.4.1.80]


id: GO:0008121
name: ubiquinol-cytochrome-c reductase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+." [EC:1.10.2.2, ISBN:0198547684]


id: GO:0008123
name: cholesterol 7-alpha-monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O." [EC:1.14.13.17]


id: GO:0008124
name: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O." [EC:4.2.1.96, RHEA:11923]


id: GO:0008125
name: obsolete pancreatic elastase I activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa." [EC:3.4.21.36]


id: GO:0008127
name: quercetin 2,3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO." [EC:1.13.11.24, RHEA:15384]


id: GO:0008129
name: obsolete actinidain activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'." [EC:3.4.22.14]


id: GO:0008130
name: obsolete neutrophil collagenase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I." [EC:3.4.24.34]


id: GO:0008131
name: primary amine oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide." [EC:1.4.3.21, EC:1.4.3.22, EC:1.4.3.4, MetaCyc:RXN-9597]


id: GO:0008132
name: obsolete pancreatic elastase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin." [EC:3.4.21.36, EC:3.4.21.71]


id: GO:0008134
name: transcription factor binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription." [ISBN:0198506732]


id: GO:0008135
name: translation factor activity, RNA binding
namespace: molecular_function
def:
  "Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome." [GOC:ai, GOC:vw]


id: GO:0008138
name: protein tyrosine/serine/threonine phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [GOC:mah]


id: GO:0008139
name: nuclear localization sequence binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus." [GOC:ai]


id: GO:0008140
name: cAMP response element binding protein binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB protein)." [GOC:mah]


id: GO:0008141
name: obsolete puparial glue (sensu Diptera)
namespace: molecular_function
def:
  "OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147)." [PMID:825230]


id: GO:0008142
name: oxysterol binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol." [http://www.onelook.com/]


id: GO:0008143
name: poly(A) binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA." [GOC:jl]


id: GO:0008144
name: drug binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease." [GOC:jl, ISBN:0198506732]


id: GO:0008145
name: phenylalkylamine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives." [GOC:jl]


id: GO:0008146
name: sulfotransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate." [EC:2.8.2, GOC:curators]


id: GO:0008148
name: obsolete negative transcription elongation factor activity
namespace: molecular_function
def:
  "OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah]


id: GO:0008150
name: biological_process
namespace: biological_process
def:
  "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete]


id: GO:0008152
name: metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684]


id: GO:0008153
name: para-aminobenzoic acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins." [ISBN:0198506732, PMID:11377864, PMID:11960743]


id: GO:0008154
name: actin polymerization or depolymerization
namespace: biological_process
def:
  "Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah]


id: GO:0008156
name: negative regulation of DNA replication
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication." [GOC:go_curators]


id: GO:0008158
name: hedgehog receptor activity
namespace: molecular_function
def:
  "Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity." [GOC:bf, GOC:go_curators, PMID:9278137]


id: GO:0008159
name: obsolete positive transcription elongation factor activity
namespace: molecular_function
def:
  "OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah]


id: GO:0008160
name: protein tyrosine phosphatase activator activity
namespace: molecular_function
def:
  "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein." [GOC:ai, ISBN:0198506732]


id: GO:0008170
name: N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule." [GOC:ai]


id: GO:0008173
name: RNA methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule." [GOC:mah]


id: GO:0008174
name: mRNA methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule." [GOC:mah]


id: GO:0008175
name: tRNA methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule." [GOC:mah]


id: GO:0008176
name: tRNA (guanine-N7-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine." [EC:2.1.1.33]


id: GO:0008177
name: succinate dehydrogenase (ubiquinone) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol." [EC:1.3.5.1, RHEA:13716]


id: GO:0008180
name: COP9 signalosome
namespace: cellular_component
def:
  "A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome." [PMID:11019806, PMID:12186635, PMID:14570571]


id: GO:0008184
name: glycogen phosphorylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate." [EC:2.4.1.1, MetaCyc:GLYCOPHOSPHORYL-RXN]


id: GO:0008186
name: RNA-dependent ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction." [EC:3.6.1.3, GOC:jl]


id: GO:0008187
name: poly-pyrimidine tract binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule." [GOC:jl]


id: GO:0008189
name: obsolete apoptosis inhibitor activity
namespace: molecular_function
def:
  "OBSOLETE. The function held by products which directly block any step in the process of apoptosis." [GOC:hb]


id: GO:0008190
name: eukaryotic initiation factor 4E binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation." [ISBN:0198506732]


id: GO:0008191
name: metalloendopeptidase inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity." [GOC:ai]


id: GO:0008192
name: RNA guanylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule." [GOC:mah]


id: GO:0008193
name: tRNA guanylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs." [PMID:1660461]


id: GO:0008194
name: UDP-glycosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule." [InterPro:IPR004224, PMID:11846783]


id: GO:0008195
name: phosphatidate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate." [EC:3.1.3.4, GOC:pr]


id: GO:0008196
name: vitellogenin receptor activity
namespace: molecular_function
def:
  "Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis." [GOC:bf, PMID:12429745]


id: GO:0008201
name: heparin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:jl, ISBN:0198506732]


id: GO:0008202
name: steroid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684]


id: GO:0008203
name: cholesterol metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues." [ISBN:0198506732]


id: GO:0008204
name: ergosterol metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light." [ISBN:0198506732]


id: GO:0008205
name: ecdysone metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development." [ISBN:0198506732]


id: GO:0008206
name: bile acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators]


id: GO:0008207
name: C21-steroid hormone metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones." [GOC:ai]


id: GO:0008208
name: C21-steroid hormone catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones." [GOC:ai]


id: GO:0008209
name: androgen metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics." [ISBN:0198506732]


id: GO:0008210
name: estrogen metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants." [ISBN:0198506732]


id: GO:0008211
name: glucocorticoid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [ISBN:0198506732]


id: GO:0008212
name: mineralocorticoid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance." [ISBN:0198506732]


id: GO:0008213
name: protein alkylation
namespace: biological_process
def:
  "The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom." [GOC:ma]


id: GO:0008214
name: protein dealkylation
namespace: biological_process
def:
  "The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom." [GOC:ai]


id: GO:0008215
name: spermine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication." [CHEBI:15746, GOC:curators]


id: GO:0008216
name: spermidine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai]


id: GO:0008217
name: regulation of blood pressure
namespace: biological_process
def:
  "Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." [GOC:dph, GOC:mtg_cardio, ISBN:0721643949]


id: GO:0008219
name: cell death
namespace: biological_process
def:
  "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395]


id: GO:0008224
name: obsolete Gram-positive antibacterial peptide activity
namespace: molecular_function
def:
  "OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells." [GOC:go_curators]


id: GO:0008225
name: obsolete Gram-negative antibacterial peptide activity
namespace: molecular_function
def:
  "OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells." [GOC:go_curators]


id: GO:0008226
name: tyramine receptor activity
namespace: molecular_function
def:
  "Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine." [http://www.onelook.com/]


id: GO:0008227
name: G-protein coupled amine receptor activity
namespace: molecular_function
def:
  "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph]


id: GO:0008228
name: opsonization
namespace: biological_process
def:
  "The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody." [GOC:add, GOC:mah, ISBN:0198506732, ISBN:068340007X, ISBN:0781735149]


id: GO:0008229
name: obsolete opsonin activity
namespace: molecular_function
def:
  "OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis." [ISBN:0198506732]


id: GO:0008230
name: ecdysone receptor holocomplex
namespace: cellular_component
def:
  "A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes." [GOC:bf, PMID:14592980]


id: GO:0008231
name: repressor ecdysone receptor complex
namespace: cellular_component
def:
  "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes." [PMID:10488333]


id: GO:0008232
name: activator ecdysone receptor complex
namespace: cellular_component
def:
  "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes." [PMID:10488333]


id: GO:0008233
name: peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181]


id: GO:0008234
name: cysteine-type peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0008235
name: metalloexopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE]


id: GO:0008236
name: serine-type peptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094]


id: GO:0008237
name: metallopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE]


id: GO:0008238
name: exopeptidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both." [http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE]


id: GO:0008242
name: omega peptidase activity
namespace: molecular_function
def:
  "Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups)." [EC:3.4.19.-]


id: GO:0008243
name: obsolete plasminogen activator activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin." [EC:3.4.21.68, EC:3.4.21.73]


id: GO:0008246
name: obsolete electron transfer flavoprotein
namespace: molecular_function
def:
  "OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system." [ISBN:0198506732]


id: GO:0008247
name: 1-alkyl-2-acetylglycerophosphocholine esterase complex
namespace: cellular_component
def:
  "An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF)." [GOC:jl, PMID:10542206]


id: GO:0008250
name: oligosaccharyltransferase complex
namespace: cellular_component
def:
  "A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected." [ISBN:0879695595, PMID:15835887]


id: GO:0008251
name: tRNA-specific adenosine deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule." [GOC:mah, IMG:00700]


id: GO:0008255
name: ecdysis-triggering hormone activity
namespace: molecular_function
def:
  "The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system." [GOC:mah, PMID:9020043]


id: GO:0008256
name: protein histidine pros-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine." [EC:2.7.13.1]


id: GO:0008257
name: protein histidine tele-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine." [EC:2.7.13.2]


id: GO:0008260
name: 3-oxoacid CoA-transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA." [EC:2.8.3.5]


id: GO:0008263
name: pyrimidine-specific mismatch base pair DNA N-glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site." [GOC:elh, PMID:9224623]


id: GO:0008265
name: Mo-molybdopterin cofactor sulfurase activity
namespace: molecular_function
def:
  "Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase." [GOC:mah, PMID:11549764]


id: GO:0008266
name: poly(U) RNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule." [GOC:mah]


id: GO:0008267
name: poly-glutamine tract binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein." [GOC:mah]


id: GO:0008269
name: JAK pathway signal transduction adaptor activity
namespace: molecular_function
def:
  "The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07]


id: GO:0008271
name: secondary active sulfate transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the secondary active transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport]


id: GO:0008272
name: sulfate transport
namespace: biological_process
def:
  "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]


id: GO:0008273
name: calcium, potassium:sodium antiporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in)." [TC:2.A.19.4.1]


id: GO:0008274
name: gamma-tubulin ring complex
namespace: cellular_component
def:
  "A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins that forms a flexible open ring structure thought to be the unit of nucleation at the minus end of a microtubule." [GOC:clt, PMID:12134075]


id: GO:0008275
name: gamma-tubulin small complex
namespace: cellular_component
def:
  "A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex." [PMID:11297925, PMID:12134075]


id: GO:0008277
name: regulation of G-protein coupled receptor protein signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity." [GOC:go_curators]


id: GO:0008278
name: cohesin complex
namespace: cellular_component
def:
  "A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3)." [GOC:sp, PMID:9887095]


id: GO:0008280
name: cohesin core heterodimer
namespace: cellular_component
def:
  "The core heterodimer of a cohesin complex; a structure required for sister chromatid cohesion in eukaryotes." [GOC:jl]


id: GO:0008281
name: sulfonylurea receptor activity
namespace: molecular_function
def:
  "Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling]


id: GO:0008282
name: ATP-sensitive potassium channel complex
namespace: cellular_component
def:
  "A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity." [GOC:bhm, PMID:16308567, PMID:16956886]


id: GO:0008283
name: cell proliferation
namespace: biological_process
def:
  "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb]


id: GO:0008284
name: positive regulation of cell proliferation
namespace: biological_process
def:
  "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators]


id: GO:0008285
name: negative regulation of cell proliferation
namespace: biological_process
def:
  "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators]


id: GO:0008286
name: insulin receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin." [GOC:ceb]


id: GO:0008287
name: protein serine/threonine phosphatase complex
namespace: cellular_component
def:
  "A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein." [GOC:bf]


id: GO:0008288
name: boss receptor activity
namespace: molecular_function
def:
  "Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [GOC:jl, GOC:signaling]


id: GO:0008290
name: F-actin capping protein complex
namespace: cellular_component
def:
  "A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments." [GOC:go_curators, ISBN:0198599560]


id: GO:0008291
name: acetylcholine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752]


id: GO:0008292
name: acetylcholine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752]


id: GO:0008293
name: torso signaling pathway
namespace: biological_process
def:
  "A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:8343949]


id: GO:0008294
name: calcium- and calmodulin-responsive adenylate cyclase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin." [EC:4.6.1.1, GOC:mah]


id: GO:0008295
name: spermidine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:go_curators, ISBN:0198506732]


id: GO:0008296
name: 3'-5'-exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule." [GOC:mah]


id: GO:0008297
name: single-stranded DNA exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule." [GOC:mah]


id: GO:0008298
name: intracellular mRNA localization
namespace: biological_process
def:
  "Any process in which mRNA is transported to, or maintained in, a specific location within the cell." [GOC:ai]


id: GO:0008299
name: isoprenoid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732]


id: GO:0008300
name: isoprenoid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732]


id: GO:0008301
name: DNA binding, bending
namespace: molecular_function
def:
  "The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:krc, GOC:vw, PMID:10710711, PMID:19037758]


id: GO:0008303
name: caspase complex
namespace: cellular_component
def:
  "A protein complex that is located in the cytosol and contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes." [GOC:cna, GOC:mtg_apoptosis]


id: GO:0008305
name: integrin complex
namespace: cellular_component
def:
  "A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands." [PMID:17543136]


id: GO:0008306
name: associative learning
namespace: biological_process
def:
  "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." [ISBN:0582227089]


id: GO:0008307
name: structural constituent of muscle
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of a muscle fiber." [GOC:mah]


id: GO:0008308
name: voltage-gated anion channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, GOC:vw, ISBN:0815340729]


id: GO:0008309
name: double-stranded DNA exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule." [GOC:mah]


id: GO:0008310
name: single-stranded DNA 3'-5' exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule." [GOC:mah, PMID:22562358]


id: GO:0008311
name: double-stranded DNA 3'-5' exodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule." [GOC:mah, PMID:22562358]


id: GO:0008312
name: 7S RNA binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP)." [GOC:jl, PMID:6181418]


id: GO:0008314
name: gurken signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken." [GOC:bf, PMID:23972992]


id: GO:0008315
name: meiotic G2/MI transition
namespace: biological_process
def:
  "The cell cycle process in which a cell progresses from meiotic prophase to metaphase I." [PMID:15088480]


id: GO:0008316
name: structural constituent of vitelline membrane
namespace: molecular_function
def:
  "The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:sensu]


id: GO:0008318
name: protein prenyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein." [GOC:mah]


id: GO:0008321
name: Ral guanyl-nucleotide exchange factor activity
namespace: molecular_function
def:
  "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah]


id: GO:0008322
name: obsolete Pro-X carboxypeptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid." [GOC:mah]


id: GO:0008324
name: cation transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of cation from one side of the membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729]


id: GO:0008327
name: methyl-CpG binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide." [GOC:jl, PMID:11746232]


id: GO:0008328
name: ionotropic glutamate receptor complex
namespace: cellular_component
def:
  "A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html]


id: GO:0008329
name: signaling pattern recognition receptor activity
namespace: molecular_function
def:
  "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity." [GOC:ar, PMID:12507420, PMID:12925128, PMID:14523544, Wikipedia:Pattern_recognition_receptor]


id: GO:0008330
name: protein tyrosine/threonine phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [GOC:mah]


id: GO:0008331
name: high voltage-gated calcium channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729, PMID:16382099]


id: GO:0008332
name: low voltage-gated calcium channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729, PMID:16382099]


id: GO:0008334
name: histone mRNA metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving an mRNA encoding a histone." [GOC:krc, GOC:mah, PMID:17855393]


id: GO:0008335
name: female germline ring canal stabilization
namespace: biological_process
def:
  "Maintenance of the structural integrity of the ring canals connecting the female germline cyst." [GOC:curators]


id: GO:0008336
name: gamma-butyrobetaine dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate." [EC:1.14.11.1, RHEA:24031]


id: GO:0008337
name: obsolete selectin
namespace: molecular_function
def:
  "OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins." [ISBN:0124325653]


id: GO:0008341
name: obsolete response to cocaine (sensu Insecta)
namespace: biological_process
def:
  "OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557)." [GOC:go_curators, GOC:jid]


id: GO:0008346
name: larval walking behavior
namespace: biological_process
def:
  "The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg." [GOC:go_curators, GOC:pr]


id: GO:0008347
name: glial cell migration
namespace: biological_process
def:
  "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu]


id: GO:0008348
name: negative regulation of antimicrobial humoral response
namespace: biological_process
def:
  "Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response." [GOC:go_curators]


id: GO:0008349
name: MAP kinase kinase kinase kinase activity
namespace: molecular_function
def:
  "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli." [GOC:bf, PMID:11790549]


id: GO:0008352
name: katanin complex
namespace: cellular_component
def:
  "A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa)." [PMID:10910766]


id: GO:0008353
name: RNA polymerase II carboxy-terminal domain kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats." [EC:2.7.11.23, GOC:mah]


id: GO:0008354
name: germ cell migration
namespace: biological_process
def:
  "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl]


id: GO:0008355
name: olfactory learning
namespace: biological_process
def:
  "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue." [ISBN:0582227089]


id: GO:0008356
name: asymmetric cell division
namespace: biological_process
def:
  "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519]


id: GO:0008358
name: maternal determination of anterior/posterior axis, embryo
namespace: biological_process
def:
  "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


id: GO:0008359
name: regulation of bicoid mRNA localization
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location." [GOC:hb]


id: GO:0008360
name: regulation of cell shape
namespace: biological_process
def:
  "Any process that modulates the surface configuration of a cell." [GOC:dph, GOC:go_curators, GOC:tb]


id: GO:0008362
name: chitin-based embryonic cuticle biosynthetic process
namespace: biological_process
def:
  "Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12019232]


id: GO:0008363
name: larval chitin-based cuticle development
namespace: biological_process
def:
  "Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008364
name: pupal chitin-based cuticle development
namespace: biological_process
def:
  "Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008365
name: adult chitin-based cuticle development
namespace: biological_process
def:
  "Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008366
name: axon ensheathment
namespace: biological_process
def:
  "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal." [GOC:jl, ISBN:0878932437]


id: GO:0008369
name: obsolete molecular function
namespace: molecular_function
def:
  "OBSOLETE. These are terms that have been removed from the active function ontology." [GOC:go_curators]


id: GO:0008370
name: obsolete cellular component
namespace: cellular_component
def:
  "OBSOLETE. These are terms that have been removed from the active component ontology." [GOC:go_curators]


id: GO:0008371
name: obsolete biological process
namespace: biological_process
def:
  "OBSOLETE. These are terms that have been removed from the active process ontology." [GOC:go_curators]


id: GO:0008373
name: sialyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins." [EC:2.4.99, GOC:cjm, Wikipedia:Sialyltransferase]


id: GO:0008375
name: acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar." [ISBN:0198506732]


id: GO:0008376
name: acetylgalactosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide." [ISBN:0198506732]


id: GO:0008377
name: light-induced release of internally sequestered calcium ion
namespace: biological_process
def:
  "The process in which the detection of light triggers the release of internally sequestered calcium ions." [GOC:ai]


id: GO:0008378
name: galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [ISBN:0198506732]


id: GO:0008379
name: thioredoxin peroxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O." [MetaCyc:RXN0-267]


id: GO:0008380
name: RNA splicing
namespace: biological_process
def:
  "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." [GOC:krc, GOC:mah]


id: GO:0008381
name: mechanically-gated ion channel activity
namespace: molecular_function
def:
  "Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress." [GOC:mtg_transport, ISBN:0815340729]


id: GO:0008385
name: IkappaB kinase complex
namespace: cellular_component
def:
  "A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:ma, PMID:12055104, PMID:20300203]


id: GO:0008386
name: cholesterol monooxygenase (side-chain-cleaving) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.6]


id: GO:0008388
name: testosterone 15-alpha-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O." [GOC:ai]


id: GO:0008389
name: coumarin 7-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+." [Reactome:163103]


id: GO:0008390
name: testosterone 16-alpha-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-alpha-hydroxytestosterone + H2O." [GOC:ai]


id: GO:0008391
name: arachidonic acid monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water." [GOC:mah]


id: GO:0008392
name: arachidonic acid epoxygenase activity
namespace: molecular_function
def:
  "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399]


id: GO:0008395
name: steroid hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2." [ISBN:0721662544]


id: GO:0008396
name: oxysterol 7-alpha-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O." [PMID:10882791]


id: GO:0008398
name: sterol 14-demethylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O." [EC:1.14.13.70]


id: GO:0008403
name: 25-hydroxycholecalciferol-24-hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol." [ISBN:0471331309]


id: GO:0008404
name: arachidonic acid 14,15-epoxygenase activity
namespace: molecular_function
def:
  "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399]


id: GO:0008405
name: arachidonic acid 11,12-epoxygenase activity
namespace: molecular_function
def:
  "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399]


id: GO:0008406
name: gonad development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732]


id: GO:0008407
name: chaeta morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell." [FBbt:00005177, GOC:bf, GOC:cjm, GOC:dos, GOC:go_curators]


id: GO:0008408
name: 3'-5' exonuclease activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end." [GOC:ai]


id: GO:0008409
name: 5'-3' exonuclease activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end." [GOC:ai]


id: GO:0008410
name: CoA-transferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)." [GOC:jl]


id: GO:0008412
name: 4-hydroxybenzoate octaprenyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate." [MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN]


id: GO:0008413
name: 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription." [PMID:15878881]


id: GO:0008417
name: fucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai]


id: GO:0008418
name: protein-N-terminal asparagine amidohydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein." [PMID:8910481]


id: GO:0008419
name: RNA lariat debranching enzyme activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide." [PMID:7519612]


id: GO:0008420
name: CTD phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate." [EC:3.1.3.16]


id: GO:0008421
name: long-chain fatty-acyl-glutamate deacylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate." [EC:3.5.1.55]


id: GO:0008422
name: beta-glucosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose." [EC:3.2.1.21]


id: GO:0008423
name: obsolete bleomycin hydrolase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred." [EC:3.4.22.40]


id: GO:0008424
name: glycoprotein 6-alpha-L-fucosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+)." [EC:2.4.1.68, RHEA:12988]


id: GO:0008425
name: 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9083048]


id: GO:0008426
name: protein kinase C inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein." [GOC:ai]


id: GO:0008428
name: ribonuclease inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:ai]


id: GO:0008429
name: phosphatidylethanolamine binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732]


id: GO:0008431
name: vitamin E binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant." [CHEBI:33234, GOC:curators, ISBN:0721662544]


id: GO:0008432
name: JUN kinase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family." [GOC:jl]


id: GO:0008434
name: calcitriol receptor activity
namespace: molecular_function
def:
  "Combining with calcitriol, the hormonally active form of vitamin D3, and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II." [CHEBI:17823, GOC:bf, GOC:signaling, PMID:16549446, PMID:17082781, Wikipedia:Calcitriol_receptor]


id: GO:0008435
name: obsolete anticoagulant activity
namespace: molecular_function
def:
  "OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation." [ISBN:0198506732]


id: GO:0008437
name: thyrotropin-releasing hormone activity
namespace: molecular_function
def:
  "The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary." [ISBN:0198506732]


id: GO:0008438
name: obsolete 1-phosphatidylinositol-5-phosphate kinase
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide." [EC:2.7.1.143]


id: GO:0008440
name: inositol-1,4,5-trisphosphate 3-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.127, RHEA:11023]


id: GO:0008441
name: 3'(2'),5'-bisphosphate nucleotidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate." [EC:3.1.3.7]


id: GO:0008442
name: 3-hydroxyisobutyrate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+." [EC:1.1.1.31]


id: GO:0008443
name: phosphofructokinase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule." [GOC:jl]


id: GO:0008444
name: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+)." [EC:2.7.8.5, RHEA:12596]


id: GO:0008445
name: D-aspartate oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide." [EC:1.4.3.1]


id: GO:0008446
name: GDP-mannose 4,6-dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O." [EC:4.2.1.47, RHEA:23823]


id: GO:0008448
name: N-acetylglucosamine-6-phosphate deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate." [EC:3.5.1.25]


id: GO:0008449
name: N-acetylglucosamine-6-sulfatase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate." [EC:3.1.6.14]


id: GO:0008450
name: obsolete O-sialoglycoprotein endopeptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated." [EC:3.4.24.57]


id: GO:0008451
name: obsolete X-Pro aminopeptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide." [EC:3.4.11.9]


id: GO:0008452
name: RNA ligase activity
namespace: molecular_function
def:
  "Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another." [GOC:mah]


id: GO:0008454
name: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R." [EC:2.4.1.145]


id: GO:0008455
name: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R." [EC:2.4.1.143]


id: GO:0008456
name: alpha-N-acetylgalactosaminidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides." [EC:3.2.1.49]


id: GO:0008457
namespace: molecular_function
name:
  beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity

def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide." [EC:2.4.1.163]


id: GO:0008458
name: carnitine O-octanoyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA." [EC:2.3.1.137, RHEA:17180]


id: GO:0008459
name: chondroitin 6-sulfotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate." [EC:2.8.2.17]


id: GO:0008460
name: dTDP-glucose 4,6-dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O." [EC:4.2.1.46, RHEA:17224]


id: GO:0008462
name: obsolete endopeptidase Clp activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs)." [EC:3.4.21.92]


id: GO:0008463
name: formylmethionine deformylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate." [EC:3.5.1.31, RHEA:17784]


id: GO:0008464
name: obsolete gamma-glutamyl hydrolase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid." [EC:3.4.19.9]


id: GO:0008467
name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S." [EC:2.8.2.23]


id: GO:0008469
name: histone-arginine N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine." [EC:2.1.1.125]


id: GO:0008470
name: isovaleryl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF." [EC:1.3.99.10]


id: GO:0008471
name: obsolete laccase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O." [EC:1.10.3.2]


id: GO:0008472
name: obsolete metallocarboxypeptidase D activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid." [EC:3.4.17.22]


id: GO:0008475
name: procollagen-lysine 5-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2." [EC:1.14.11.4]


id: GO:0008476
name: protein-tyrosine sulfotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate." [EC:2.8.2.20]


id: GO:0008480
name: sarcosine dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein." [EC:1.5.8.3, RHEA:19796]


id: GO:0008482
name: sulfite oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate." [EC:1.8.3.1, RHEA:24603]


id: GO:0008483
name: transaminase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid." [ISBN:0198506732]


id: GO:0008484
name: sulfuric ester hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2." [GOC:ai]


id: GO:0008486
name: diphosphoinositol-polyphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate." [EC:3.6.1.52]


id: GO:0008488
name: gamma-glutamyl carboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide." [PMID:18374194]


id: GO:0008489
name: UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base." [MetaCyc:RXN-10764, PMID:9593693]


id: GO:0008490
name: arsenite secondary active transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:jl]


id: GO:0008493
name: tetracycline transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of tetracycline into, out of or within a cell, or between cells. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [CHEBI:27902, GOC:curators]


id: GO:0008494
name: translation activator activity
namespace: molecular_function
def:
  "Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide." [GOC:ai]


id: GO:0008495
name: protoheme IX farnesyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate." [MetaCyc:HEMEOSYN-RXN]


id: GO:0008496
name: mannan endo-1,6-alpha-mannosidase activity
namespace: molecular_function
def:
  "Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans." [EC:3.2.1.101]


id: GO:0008498
name: obsolete phospholipid scrambling
namespace: molecular_function
def:
  "OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions." [OMIM:604170]


id: GO:0008499
name: UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP." [PMID:10212226]


id: GO:0008502
name: melatonin receptor activity
namespace: molecular_function
def:
  "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin." [GOC:ai, ISBN:0198506732]


id: GO:0008503
name: benzodiazepine receptor activity
namespace: molecular_function
def:
  "Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity." [GOC:jl]


id: GO:0008504
name: monoamine transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of the membrane to the other." [CHEBI:25375, GOC:mah]


id: GO:0008506
name: sucrose:proton symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in)." [TC:2.A.1.5.3]


id: GO:0008507
name: sodium:iodide symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in)." [TC:2.A.21.5.1]


id: GO:0008508
name: bile acid:sodium symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)." [TC:2.A.28.-.-]


id: GO:0008509
name: anion transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of a negatively charged ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729]


id: GO:0008510
name: sodium:bicarbonate symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in)." [TC:2.A.31.2.1]


id: GO:0008511
name: sodium:potassium:chloride symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in)." [TC:2.A.30.1.1]


id: GO:0008512
name: sulfate:proton symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in)." [TC:2.A.53.-.-]


id: GO:0008513
name: secondary active organic cation transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of organic cations from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:curators]


id: GO:0008514
name: organic anion transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai]


id: GO:0008515
name: sucrose transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of sucrose from one side of the membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


id: GO:0008516
name: hexose uniporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in)." [TC:2.A.1.1.5]


id: GO:0008517
name: folic acid transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:ai]


id: GO:0008518
name: reduced folate carrier activity
namespace: molecular_function
def:
  "Catalysis of the transfer of reduced folate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport]


id: GO:0008519
name: ammonium transmembrane transporter activity
namespace: molecular_function
def:
  "Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals." [GOC:go_curators, ISBN:0198506732]


id: GO:0008520
name: L-ascorbate:sodium symporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ascorbate(out) + Na+(out) = ascorbate(in) + Na+(in)." [TC:2.A.40.6.1]


id: GO:0008521
name: acetyl-CoA transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GOC:ai]


id: GO:0008523
name: sodium-dependent multivitamin transmembrane transporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate." [TC:2.A.21.5.2]


id: GO:0008524
name: glucose 6-phosphate:phosphate antiporter activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out)." [TC:2.A.1.-.-]


id: GO:0008525
name: phosphatidylcholine transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:ai, ISBN:0198506732]


id: GO:0008526
name: phosphatidylinositol transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of phosphatidylinositol into, out of or within a cell, or between cells. Phosphatidylinositol refers to any glycophospholipids with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [GOC:ai, ISBN:0198506732]


id: GO:0008527
name: taste receptor activity
namespace: molecular_function
def:
  "Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste." [GOC:dph]


id: GO:0008528
name: G-protein coupled peptide receptor activity
namespace: molecular_function
def:
  "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:dph, GOC:tb]


id: GO:0008532
name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.149]


id: GO:0008533
name: obsolete astacin activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'." [EC:3.4.24.21]


id: GO:0008534
name: oxidized purine nucleobase lesion DNA N-glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]


id: GO:0008535
name: respiratory chain complex IV assembly
namespace: biological_process
def:
  "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms." [GOC:jl, http://www.med.wright.edu/bmb/lp/lplab.htm]


id: GO:0008536
name: Ran GTPase binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly." [GOC:rn, PMID:12787777, PMID:14726649]


id: GO:0008537
name: proteasome activator complex
namespace: cellular_component
def:
  "A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex." [GOC:rb]


id: GO:0008538
name: obsolete proteasome activator activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:rn, PMID:10428771]


id: GO:0008539
name: obsolete proteasome inhibitor activity
namespace: molecular_function
def:
  "OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:mah]


id: GO:0008540
name: proteasome regulatory particle, base subcomplex
namespace: cellular_component
def:
  "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex." [GOC:mtg_sensu, GOC:rb]


id: GO:0008541
name: proteasome regulatory particle, lid subcomplex
namespace: cellular_component
def:
  "The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:rb]


id: GO:0008542
name: visual learning
namespace: biological_process
def:
  "Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue." [GOC:jid, ISBN:0582227089]


id: GO:0008543
name: fibroblast growth factor receptor signaling pathway
namespace: biological_process
def:
  "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." [GOC:ceb]


id: GO:0008544
name: epidermis development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003]


id: GO:0008545
name: JUN kinase kinase activity
namespace: molecular_function
def:
  "Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase." [GOC:bf, PMID:11057897, PMID:11790549]


id: GO:0008546
name: obsolete microtubule/chromatin interaction
namespace: biological_process
def:
  "OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins." [PMID:10322137]


id: GO:0008547
name: obsolete protein-synthesizing GTPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs." [EC:3.6.5.3, MetaCyc:3.6.1.48-RXN]


id: GO:0008548
name: obsolete signal-recognition-particle GTPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis." [EC:3.6.5.4, MetaCyc:3.6.1.49-RXN]


id: GO:0008549
name: obsolete dynamin GTPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles." [EC:3.6.5.5, MetaCyc:3.6.1.50-RXN]


id: GO:0008550
name: obsolete tubulin GTPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others." [EC:3.6.5.6, MetaCyc:3.6.1.51-RXN]


id: GO:0008551
name: cadmium-exporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out)." [EC:3.6.3.3]


id: GO:0008552
name: obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+." [TC:3.A.3.6.2]


id: GO:0008553
name: hydrogen-exporting ATPase activity, phosphorylative mechanism
namespace: molecular_function
def:
  "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle." [EC:3.6.3.6]


id: GO:0008554
name: sodium-exporting ATPase activity, phosphorylative mechanism
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism." [EC:3.6.3.7]


id: GO:0008555
name: chloride-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in)." [EC:3.6.3.11]


id: GO:0008556
name: potassium-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in)." [EC:3.6.3.12]


id: GO:0008558
name: guanine-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in)." [EC:3.6.3.37]


id: GO:0008559
name: xenobiotic-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out)." [EC:3.6.3.44]


id: GO:0008563
name: obsolete alpha-factor sex pheromone exporter
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process." [EC:3.6.3.48]


id: GO:0008564
name: protein-exporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins." [EC:3.6.3.50]


id: GO:0008565
name: protein transporter activity
namespace: molecular_function
def:
  "Enables the directed movement of proteins into, out of or within a cell, or between cells." [ISBN:0198506732]


id: GO:0008566
name: mitochondrial protein-transporting ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex." [EC:3.6.3.51]


id: GO:0008567
name: obsolete dynein ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome." [EC:3.6.4.2]


id: GO:0008568
name: microtubule-severing ATPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP." [EC:3.6.4.3, PMID:10910766]


id: GO:0008569
name: ATP-dependent microtubule motor activity, minus-end-directed
namespace: molecular_function
def:
  "Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP." [EC:3.6.4.5, GOC:mah, GOC:vw]


id: GO:0008570
name: obsolete myosin ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction." [EC:3.6.4.1]


id: GO:0008571
name: obsolete non-chaperonin molecular chaperone ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin." [EC:3.6.4.10]


id: GO:0008572
name: obsolete nucleoplasmin ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes." [EC:3.6.4.11]


id: GO:0008573
name: obsolete peroxisome-assembly ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle." [EC:3.6.4.7]


id: GO:0008574
name: ATP-dependent microtubule motor activity, plus-end-directed
namespace: molecular_function
def:
  "Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP." [EC:3.6.4.4, GOC:vw]


id: GO:0008575
name: obsolete proteasome ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome." [EC:3.6.4.8]


id: GO:0008576
name: obsolete vesicle-fusing ATPase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments." [EC:3.6.4.6]


id: GO:0008579
name: JUN kinase phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate." [GOC:mah]


id: GO:0008581
name: obsolete ubiquitin-specific protease 5 activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin." [ISBN:0120793709, MEROPS:c19p001]


id: GO:0008582
name: regulation of synaptic growth at neuromuscular junction
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions." [GOC:go_curators]


id: GO:0008583
name: mystery cell differentiation
namespace: biological_process
def:
  "The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster." [ISBN:0632030488, PMID:1295747]


id: GO:0008584
name: male gonad development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid]


id: GO:0008585
name: female gonad development
namespace: biological_process
def:
  "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb]


id: GO:0008586
name: imaginal disc-derived wing vein morphogenesis
namespace: biological_process
def:
  "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized." [GOC:mtg_sensu]


id: GO:0008587
name: imaginal disc-derived wing margin morphogenesis
namespace: biological_process
def:
  "The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238]


id: GO:0008588
name: release of cytoplasmic sequestered NF-kappaB
namespace: biological_process
def:
  "The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus." [GOC:jl]


id: GO:0008589
name: regulation of smoothened signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of smoothened signaling." [GOC:go_curators]


id: GO:0008591
name: regulation of Wnt signaling pathway, calcium modulating pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:dph, GOC:go_curators, GOC:tb]


id: GO:0008592
name: regulation of Toll signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators]


id: GO:0008593
name: regulation of Notch signaling pathway
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators]


id: GO:0008594
name: photoreceptor cell morphogenesis
namespace: biological_process
def:
  "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah]


id: GO:0008595
name: anterior/posterior axis specification, embryo
namespace: biological_process
def:
  "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


id: GO:0008597
name: calcium-dependent protein serine/threonine phosphatase regulator activity
namespace: molecular_function
def:
  "Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase." [EC:3.1.3.16, GOC:ai]


id: GO:0008608
name: attachment of spindle microtubules to kinetochore
namespace: biological_process
def:
  "The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex." [GOC:vw, PMID:10322137]


id: GO:0008609
name: alkylglycerone-phosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion." [EC:2.5.1.26]


id: GO:0008610
name: lipid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators]


id: GO:0008611
name: ether lipid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol." [GOC:ma, ISBN:0198547684, PMID:15337120]


id: GO:0008612
name: peptidyl-lysine modification to peptidyl-hypusine
namespace: biological_process
def:
  "The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine." [GOC:ma, ISBN:0198547684, RESID:AA0116]


id: GO:0008613
name: diuretic hormone activity
namespace: molecular_function
def:
  "The action characteristic of a diuretic hormone, any peptide hormone that, upon receptor binding, regulates water balance and fluid secretion." [GOC:mah, InterPro:IPR003621, PMID:8618894]


id: GO:0008614
name: pyridoxine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [CHEBI:16709, GOC:curators]


id: GO:0008615
name: pyridoxine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds." [GOC:ai]


id: GO:0008616
name: queuosine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents." [GOC:go_curators, ISBN:0198506732]


id: GO:0008617
name: guanosine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution." [ISBN:0198506732]


id: GO:0008618
name: 7-methylguanosine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA." [ISBN:0198506732]


id: GO:0008622
name: epsilon DNA polymerase complex
namespace: cellular_component
def:
  "A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair." [PMID:15814431, PMID:9745046]


id: GO:0008623
name: CHRAC
namespace: cellular_component
def:
  "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair." [GOC:bf, GOC:krc, PMID:15284901, PMID:16568949, PMID:21810179, PMID:9252192]


id: GO:0008625
name: extrinsic apoptotic signaling pathway via death domain receptors
namespace: biological_process
def:
  "A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0008626
name: granzyme-mediated apoptotic signaling pathway
namespace: biological_process
def:
  "A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells." [GOC:mtg_apoptosis, PMID:17158907]


id: GO:0008627
name: intrinsic apoptotic signaling pathway in response to osmotic stress
namespace: biological_process
def:
  "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, PMID:11454444, PMID:16483738]


id: GO:0008628
name: hormone-mediated apoptotic signaling pathway
namespace: biological_process
def:
  "A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered." [GOC:bf, GOC:mtg_apoptosis]


id: GO:0008630
name: intrinsic apoptotic signaling pathway in response to DNA damage
namespace: biological_process
def:
  "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." [GOC:go_curators, GOC:mtg_apoptosis]


id: GO:0008631
name: intrinsic apoptotic signaling pathway in response to oxidative stress
namespace: biological_process
def:
  "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered." [GOC:ai, GOC:mtg_apoptosis]


id: GO:0008633
name: obsolete activation of pro-apoptotic gene products
namespace: biological_process
def:
  "OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0008634
name: obsolete negative regulation of survival gene product expression
namespace: biological_process
def:
  "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb]


id: GO:0008635
name: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
namespace: biological_process
def:
  "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c." [GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, Wikipedia:Caspase]


id: GO:0008636
name: obsolete activation of caspase activity by protein phosphorylation
namespace: biological_process
def:
  "OBSOLETE. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group." [GOC:dph, GOC:jl, GOC:tb, PMID:14744432, Wikipedia:Caspase]


id: GO:0008637
name: apoptotic mitochondrial changes
namespace: biological_process
def:
  "The morphological and physiological alterations undergone by mitochondria during apoptosis." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0008638
name: obsolete protein tagging activity
namespace: molecular_function
def:
  "OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation." [GOC:jl]


id: GO:0008641
name: small protein activating enzyme activity
namespace: molecular_function
def:
  "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:jl, GOC:mah]


id: GO:0008643
name: carbohydrate transport
namespace: biological_process
def:
  "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai]


id: GO:0008645
name: hexose transport
namespace: biological_process
def:
  "The directed movement of hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule." [GOC:ai]


id: GO:0008646
name: high-affinity hexose transport
namespace: biological_process
def:
  "The directed, high-affinity movement of a hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mah]


id: GO:0008647
name: low-affinity hexose transport
namespace: biological_process
def:
  "The directed, low-affinity movement of a hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations." [GOC:mah]


id: GO:0008648
name: obsolete tachykinin
namespace: molecular_function
def:
  "OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation." [ISBN:0198506732, ISBN:0721662544]


id: GO:0008649
name: rRNA methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule." [GOC:mah]


id: GO:0008650
name: rRNA (uridine-2'-O-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine." [GOC:mah]


id: GO:0008652
name: cellular amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732]


id: GO:0008653
name: lipopolysaccharide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [ISBN:0198506732]


id: GO:0008654
name: phospholipid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [ISBN:0198506732]


id: GO:0008655
name: pyrimidine-containing compound salvage
namespace: biological_process
def:
  "Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis." [CHEBI:39447, GOC:jl]


id: GO:0008656
name: cysteine-type endopeptidase activator activity involved in apoptotic process
namespace: molecular_function
def:
  "Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process." [GOC:mah, GOC:mtg_apoptosis]


id: GO:0008657
name: DNA topoisomerase (ATP-hydrolyzing) inhibitor activity
namespace: molecular_function
def:
  "Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:mah]


id: GO:0008658
name: penicillin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:ai]


id: GO:0008659
name: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.-, GOC:ai]


id: GO:0008660
name: 1-aminocyclopropane-1-carboxylate deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+)." [EC:3.5.99.7, RHEA:16936]


id: GO:0008661
name: 1-deoxy-D-xylulose-5-phosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2)." [EC:2.2.1.7, RHEA:12608]


id: GO:0008662
name: 1-phosphofructokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate." [EC:2.7.1.56]


id: GO:0008663
name: 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate." [EC:3.1.4.16]


id: GO:0008664
name: 2'-5'-RNA ligase activity
namespace: molecular_function
def:
  "Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another." [GOC:mah, PMID:8940112]


id: GO:0008665
name: 2'-phosphotransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a phosphate group from one compound to the 2' position of another." [GOC:jl, GOC:mah]


id: GO:0008666
name: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA." [EC:2.3.1.117, RHEA:17328]


id: GO:0008667
name: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH." [EC:1.3.1.28, RHEA:23827]


id: GO:0008668
name: (2,3-dihydroxybenzoyl)adenylate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate." [EC:2.7.7.58, RHEA:20232]


id: GO:0008670
name: 2,4-dienoyl-CoA reductase (NADPH) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+." [EC:1.3.1.34]


id: GO:0008671
name: 2-dehydro-3-deoxygalactonokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+)." [EC:2.7.1.58, RHEA:16528]


id: GO:0008672
name: 2-dehydro-3-deoxyglucarate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde." [EC:4.1.2.20]


id: GO:0008673
name: 2-dehydro-3-deoxygluconokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+)." [EC:2.7.1.45, RHEA:14800]


id: GO:0008674
name: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate." [EC:4.1.2.21, RHEA:24467]


id: GO:0008675
name: 2-dehydro-3-deoxy-phosphogluconate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.14]


id: GO:0008676
name: 3-deoxy-8-phosphooctulonate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate." [EC:2.5.1.55, RHEA:14056]


id: GO:0008677
name: 2-dehydropantoate 2-reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH." [EC:1.1.1.169, RHEA:16236]


id: GO:0008678
name: 2-deoxy-D-gluconate 3-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+." [EC:1.1.1.125]


id: GO:0008679
name: 2-hydroxy-3-oxopropionate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+." [EC:1.1.1.60]


id: GO:0008681
name: 2-octaprenyl-6-methoxyphenol hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O." [MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN]


id: GO:0008682
name: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone." [MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN]


id: GO:0008683
name: 2-oxoglutarate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde." [EC:4.1.1.71, RHEA:10527]


id: GO:0008685
name: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP." [EC:4.6.1.12, RHEA:23867]


id: GO:0008686
name: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)." [EC:4.1.99.12, RHEA:18460]


id: GO:0008687
name: 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+)." [EC:1.13.11.15, RHEA:15636]


id: GO:0008688
name: 3-(3-hydroxyphenyl)propionate hydroxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O." [MetaCyc:MHPHYDROXY-RXN]


id: GO:0008689
name: 3-demethylubiquinone-9 3-O-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9." [GOC:dph]


id: GO:0008690
name: 3-deoxy-manno-octulosonate cytidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate." [EC:2.7.7.38]


id: GO:0008691
name: 3-hydroxybutyryl-CoA dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+." [EC:1.1.1.157]


id: GO:0008693
name: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.60]


id: GO:0008694
name: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2." [MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN]


id: GO:0008695
name: 3-phenylpropionate dioxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol." [UM-BBD_enzymeID:e0307]


id: GO:0008696
name: 4-amino-4-deoxychorismate lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate." [EC:4.1.3.38, RHEA:16204]


id: GO:0008697
name: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate." [EC:5.3.1.17, RHEA:23899]


id: GO:0008701
name: 4-hydroxy-2-oxovalerate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate." [EC:4.1.3.39, RHEA:22627]


id: GO:0008703
name: 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH." [EC:1.1.1.193, RHEA:17848]


id: GO:0008704
name: 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate." [EC:5.3.3.10]


id: GO:0008705
name: methionine synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine." [EC:2.1.1.13, RHEA:11175]


id: GO:0008706
name: 6-phospho-beta-glucosidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose." [EC:3.2.1.86]


id: GO:0008707
name: 4-phytase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate." [EC:3.1.3.26]


id: GO:0008709
name: cholate 7-alpha-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH." [EC:1.1.1.159, RHEA:19412]


id: GO:0008710
name: 8-amino-7-oxononanoate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA." [EC:2.3.1.47, RHEA:20715]


id: GO:0008712
name: ADP-glyceromanno-heptose 6-epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose." [EC:5.1.3.20, RHEA:17580]


id: GO:0008713
name: ADP-heptose-lipopolysaccharide heptosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+." [MetaCyc:RXN0-5061]


id: GO:0008715
name: CDP-diacylglycerol diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+)." [EC:3.6.1.26, RHEA:15224]


id: GO:0008716
name: D-alanine-D-alanine ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate." [EC:6.3.2.4, RHEA:11227]


id: GO:0008718
name: D-amino-acid dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor." [EC:1.4.99.1]


id: GO:0008719
name: dihydroneopterin triphosphate 2'-epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate." [MetaCyc:H2NTPEPIM-RXN]


id: GO:0008720
name: D-lactate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate." [EC:1.1.1.28, RHEA:16372]


id: GO:0008724
name: obsolete DNA topoisomerase IV activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo." [EC:5.99.1.-, PMID:11274059]


id: GO:0008725
name: DNA-3-methyladenine glycosylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site." [EC:3.2.2.20, GOC:elh, PMID:10872450, PMID:9224623]


id: GO:0008726
name: alkanesulfonate monooxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN." [MetaCyc:RXN0-280]


id: GO:0008727
name: GDP-mannose mannosyl hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+." [MetaCyc:GDPMANMANHYDRO-RXN]


id: GO:0008728
name: GTP diphosphokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate." [EC:2.7.6.5]


id: GO:0008732
name: L-allo-threonine aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde." [MetaCyc:LTAA-RXN, PMID:9228760]


id: GO:0008737
name: L-fuculokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.51, RHEA:12379]


id: GO:0008738
name: L-fuculose-phosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate." [EC:4.1.2.17, RHEA:12936]


id: GO:0008741
name: ribulokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate." [EC:2.7.1.16]


id: GO:0008742
name: L-ribulose-phosphate 4-epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate." [EC:5.1.3.4, RHEA:22371]


id: GO:0008743
name: L-threonine 3-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH." [EC:1.1.1.103, RHEA:25657]


id: GO:0008745
name: N-acetylmuramoyl-L-alanine amidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides." [EC:3.5.1.28]


id: GO:0008747
name: N-acetylneuraminate lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate." [EC:4.1.3.3, RHEA:23299]


id: GO:0008748
name: N-ethylmaleimide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+." [MetaCyc:RXN0-5101]


id: GO:0008750
name: NAD(P)+ transhydrogenase (AB-specific) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+." [EC:1.6.1.2, http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf]


id: GO:0008755
name: O antigen polymerase activity
namespace: molecular_function
def:
  "Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide." [GOC:jl, PMID:12045108]


id: GO:0008756
name: o-succinylbenzoate-CoA ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate." [EC:6.2.1.26]


id: GO:0008757
name: S-adenosylmethionine-dependent methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate." [GOC:mah]


id: GO:0008758
name: UDP-2,3-diacylglucosamine hydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP." [MetaCyc:LIPIDXSYNTHESIS-RXN, PMID:12000770]


id: GO:0008759
name: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
namespace: molecular_function
def:
  "Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine." [PMID:10026271]


id: GO:0008760
name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine." [EC:2.5.1.7, RHEA:18684]


id: GO:0008762
name: UDP-N-acetylmuramate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+." [EC:1.1.1.158]


id: GO:0008763
name: UDP-N-acetylmuramate-L-alanine ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine." [EC:6.3.2.8, RHEA:23375]


id: GO:0008764
name: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate." [EC:6.3.2.9, RHEA:16432]


id: GO:0008765
name: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate." [EC:6.3.2.13, RHEA:23679]


id: GO:0008766
name: UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine." [EC:6.3.2.15]


id: GO:0008770
name: [acyl-carrier-protein] phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein." [EC:3.1.4.14]


id: GO:0008771
name: [citrate (pro-3S)-lyase] ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form)." [EC:6.2.1.22]


id: GO:0008772
name: [isocitrate dehydrogenase (NADP+)] kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate." [EC:2.7.11.5]


id: GO:0008773
name: [protein-PII] uridylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII)." [EC:2.7.7.59]


id: GO:0008779
name: acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine." [EC:2.3.1.40]


id: GO:0008780
name: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine." [EC:2.3.1.129]


id: GO:0008781
name: N-acylneuraminate cytidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate." [EC:2.7.7.43]


id: GO:0008782
name: adenosylhomocysteine nucleosidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine." [EC:3.2.2.9]


id: GO:0008785
name: alkyl hydroperoxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol." [UM-BBD_reactionID:r0684]


id: GO:0008788
name: alpha,alpha-phosphotrehalase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate." [EC:3.2.1.93]


id: GO:0008789
name: altronate dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O." [EC:4.2.1.7, RHEA:15960]


id: GO:0008791
name: arginine N-succinyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine." [EC:2.3.1.109]


id: GO:0008793
name: aromatic-amino-acid:2-oxoglutarate aminotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate." [EC:2.6.1.57]


id: GO:0008794
name: arsenate reductase (glutaredoxin) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione." [EC:1.20.4.1, GOC:kd, PMID:10593884]


id: GO:0008796
name: bis(5'-nucleosyl)-tetraphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides." [GOC:ai]


id: GO:0008798
name: beta-aspartyl-peptidase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide." [EC:3.4.19.5]


id: GO:0008801
name: beta-phosphoglucomutase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate." [EC:5.4.2.6, RHEA:20116]


id: GO:0008803
name: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+)." [EC:3.6.1.41, RHEA:24255]


id: GO:0008805
name: carbon-monoxide oxygenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561." [EC:1.2.2.4]


id: GO:0008806
name: carboxymethylenebutenolidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate." [EC:3.1.1.45]


id: GO:0008807
name: carboxyvinyl-carboxyphosphonate phosphorylmutase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2." [EC:2.7.8.23]


id: GO:0008808
name: cardiolipin synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol." [GOC:jl]


id: GO:0008810
name: cellulase activity
namespace: molecular_function
def:
  "Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans." [EC:3.2.1.4]


id: GO:0008811
name: chloramphenicol O-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA." [EC:2.3.1.28, RHEA:18424]


id: GO:0008817
name: cob(I)yrinic acid a,c-diamide adenosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin." [EC:2.5.1.17]


id: GO:0008818
name: cobalamin 5'-phosphate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP." [MetaCyc:COBALAMIN5PSYN-RXN]


id: GO:0008819
name: cobinamide kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate." [http://www.mblab.gla.ac.uk/, PMID:1655696]


id: GO:0008820
name: cobinamide phosphate guanylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate." [EC:2.7.7.62, RHEA:22715]


id: GO:0008821
name: crossover junction endodeoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)." [EC:3.1.22.4]


id: GO:0008825
name: cyclopropane-fatty-acyl-phospholipid synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid." [EC:2.1.1.79]


id: GO:0008827
name: cytochrome o ubiquinol oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2O; cytochrome O is the electron acceptor." [GOC:mah, MetaCyc:CYT-UBIQUINOL-OXID-RXN]


id: GO:0008830
name: dTDP-4-dehydrorhamnose 3,5-epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose." [EC:5.1.3.13, RHEA:16972]


id: GO:0008831
name: dTDP-4-dehydrorhamnose reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH." [EC:1.1.1.133, RHEA:21799]


id: GO:0008832
name: dGTPase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate." [EC:3.1.5.1, RHEA:15196]


id: GO:0008833
name: deoxyribonuclease IV (phage-T4-induced) activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products." [EC:3.1.21.2]


id: GO:0008834
name: di-trans,poly-cis-decaprenylcistransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate." [EC:2.5.1.31]


id: GO:0008835
name: diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+)." [EC:3.5.4.26, RHEA:21871]


id: GO:0008836
name: diaminopimelate decarboxylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2)." [EC:4.1.1.20, RHEA:15104]


id: GO:0008837
name: diaminopimelate epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate." [EC:5.1.1.7, RHEA:15396]


id: GO:0008839
name: 4-hydroxy-tetrahydrodipicolinate reductase
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+." [EC:1.17.1.8]


id: GO:0008840
name: 4-hydroxy-tetrahydrodipicolinate synthase
namespace: molecular_function
def:
  "Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O." [EC:4.3.3.7, RHEA:14848]


id: GO:0008841
name: dihydrofolate synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate." [EC:6.3.2.12]


id: GO:0008842
name: diphosphate-purine nucleoside kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide." [EC:2.7.1.143]


id: GO:0008843
name: endochitinase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain." [EC:3.2.1.-, GOC:bf, GOC:kah, GOC:pde, PMID:11468293]


id: GO:0008846
name: obsolete endopeptidase La activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP." [EC:3.4.21.53]


id: GO:0008847
name: Enterobacter ribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.6]


id: GO:0008849
name: enterochelin esterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+." [MetaCyc:RXN0-1661, PMID:4565531]


id: GO:0008852
name: exodeoxyribonuclease I activity
namespace: molecular_function
def:
  "Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.1]


id: GO:0008853
name: exodeoxyribonuclease III activity
namespace: molecular_function
def:
  "Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.2]


id: GO:0008854
name: exodeoxyribonuclease V activity
namespace: molecular_function
def:
  "Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides." [EC:3.1.11.5]


id: GO:0008855
name: exodeoxyribonuclease VII activity
namespace: molecular_function
def:
  "Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides." [EC:3.1.11.6]


id: GO:0008856
name: exodeoxyribonuclease X activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes." [EC:3.1.22.5]


id: GO:0008859
name: exoribonuclease II activity
namespace: molecular_function
def:
  "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction." [EC:3.1.13.1, ISBN:0198547684]


id: GO:0008860
name: ferredoxin-NAD+ reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+." [EC:1.18.1.3]


id: GO:0008864
name: formyltetrahydrofolate deformylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)." [EC:3.5.1.10, RHEA:19836]


id: GO:0008866
name: fructuronate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH." [EC:1.1.1.57, RHEA:15732]


id: GO:0008867
name: galactarate dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O." [EC:4.2.1.42, RHEA:16008]


id: GO:0008868
name: galactitol-1-phosphate 5-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: galactitol-1-phosphate + NAD+ = L-tagatose 6-phosphate + NADH + H+." [EC:1.1.1.251]


id: GO:0008869
name: galactonate dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O." [EC:4.2.1.6, RHEA:18652]


id: GO:0008870
name: galactoside O-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside." [EC:2.3.1.18]


id: GO:0008871
name: aminoglycoside 2''-nucleotidyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside." [EC:2.7.7.46, GOC:cb]


id: GO:0008873
name: gluconate 2-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215]


id: GO:0008874
name: gluconate 5-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.69]


id: GO:0008875
name: gluconate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215, EC:1.1.1.69]


id: GO:0008876
name: quinoprotein glucose dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol." [EC:1.1.5.2]


id: GO:0008877
name: glucose-1-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate." [EC:3.1.3.10]


id: GO:0008878
name: glucose-1-phosphate adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate." [EC:2.7.7.27, RHEA:12123]


id: GO:0008879
name: glucose-1-phosphate thymidylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose." [EC:2.7.7.24, RHEA:15228]


id: GO:0008882
name: [glutamate-ammonia-ligase] adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]." [EC:2.7.7.42]


id: GO:0008883
name: glutamyl-tRNA reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH." [EC:1.2.1.70, RHEA:12347]


id: GO:0008884
name: glutathionylspermidine amidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine." [EC:3.5.1.78]


id: GO:0008885
name: glutathionylspermidine synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate." [EC:6.3.1.8]


id: GO:0008886
name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH." [EC:1.2.1.9, RHEA:14672]


id: GO:0008887
name: glycerate kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+)." [EC:2.7.1.31, RHEA:23519]


id: GO:0008889
name: glycerophosphodiester phosphodiesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate." [EC:3.1.4.46]


id: GO:0008890
name: glycine C-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+)." [EC:2.3.1.29, RHEA:20739]


id: GO:0008893
name: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate." [EC:3.1.7.2]


id: GO:0008894
name: guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate." [EC:3.6.1.40]


id: GO:0008897
name: holo-[acyl-carrier-protein] synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form." [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709]


id: GO:0008898
name: S-adenosylmethionine-homocysteine S-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine." [EC:2.1.1.10, GOC:BHF, GOC:dph]


id: GO:0008899
name: homoserine O-succinyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA." [EC:2.3.1.46, RHEA:22011]


id: GO:0008900
name: hydrogen:potassium-exchanging ATPase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in)." [EC:3.6.3.10]


id: GO:0008901
name: ferredoxin hydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2." [EC:1.12.7.2]


id: GO:0008902
name: hydroxymethylpyrimidine kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+)." [EC:2.7.1.49, RHEA:23099]


id: GO:0008903
name: hydroxypyruvate isomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate." [EC:5.3.1.22, RHEA:11955]


id: GO:0008904
name: hygromycin-B 7''-O-phosphotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+)." [EC:2.7.1.119, RHEA:23391]


id: GO:0008908
name: isochorismatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate." [EC:3.3.2.1, RHEA:11115]


id: GO:0008910
name: kanamycin kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate." [EC:2.7.1.95, RHEA:24259]


id: GO:0008913
name: lauroyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another." [GOC:jl, ISBN:0198506732]


id: GO:0008915
name: lipid-A-disaccharide synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP." [EC:2.4.1.182, RHEA:22671]


id: GO:0008917
name: lipopolysaccharide N-acetylglucosaminyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide." [EC:2.4.1.56, GOC:mr, KEGG:00540]


id: GO:0008918
name: lipopolysaccharide 3-alpha-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide." [EC:2.4.1.44, GOC:mr, KEGG:00540]


id: GO:0008919
name: lipopolysaccharide glucosyltransferase I activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide." [EC:2.4.1.58, GOC:mr, KEGG:00540]


id: GO:0008920
name: lipopolysaccharide heptosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+." [MetaCyc:RXN0-5061, MetaCyc:RXN0-5122, MetaCyc:RXN0-5127]


id: GO:0008921
name: lipopolysaccharide-1,6-galactosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide." [GOC:ai]


id: GO:0008922
name: long-chain fatty acid [acyl-carrier-protein] ligase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22." [CHEBI:15904, EC:6.2.1.20]


id: GO:0008924
name: malate dehydrogenase (quinone) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol." [MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN]


id: GO:0008926
name: mannitol-1-phosphate 5-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.17]


id: GO:0008927
name: mannonate dehydratase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O." [EC:4.2.1.8, RHEA:20100]


id: GO:0008928
name: mannose-1-phosphate guanylyltransferase (GDP) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate." [EC:2.7.7.22, RHEA:12908]


id: GO:0008929
name: methylglyoxal synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate." [EC:4.2.3.3, RHEA:17940]


id: GO:0008930
name: methylthioadenosine nucleosidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose." [EC:3.2.2.16]


id: GO:0008932
name: lytic endotransglycosylase activity
namespace: molecular_function
def:
  "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends." [PMID:10964424, PMID:9642199]


id: GO:0008933
name: lytic transglycosylase activity
namespace: molecular_function
def:
  "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues." [PMID:10964424]


id: GO:0008934
name: inositol monophosphate 1-phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25]


id: GO:0008935
name: 1,4-dihydroxy-2-naphthoyl-CoA synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O." [EC:4.1.3.36]


id: GO:0008937
name: ferredoxin-NAD(P) reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+." [EC:1.18.1.-]


id: GO:0008938
name: nicotinate N-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine." [EC:2.1.1.7, RHEA:20244]


id: GO:0008939
name: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate." [EC:2.4.2.21, RHEA:11199]


id: GO:0008942
name: nitrite reductase [NAD(P)H] activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+." [EC:1.7.1.4]


id: GO:0008943
name: obsolete glyceraldehyde-3-phosphate dehydrogenase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+." [EC:1.2.1.12, EC:1.2.1.13, EC:1.2.1.9]


id: GO:0008944
name: obsolete oligopeptidase A activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5." [EC:3.4.24.70]


id: GO:0008945
name: obsolete oligopeptidase B activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline." [EC:3.4.21.83]


id: GO:0008946
name: oligonucleotidase activity
namespace: molecular_function
def:
  "Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates." [EC:3.1.13.3]


id: GO:0008947
name: obsolete omptin activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys." [EC:3.4.21.87]


id: GO:0008951
name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein]." [MetaCyc:PALMITOTRANS-RXN]


id: GO:0008955
name: peptidoglycan glycosyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate." [EC:2.4.1.129]


id: GO:0008956
name: obsolete peptidyl-dipeptidase Dcp activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly." [EC:3.4.15.5]


id: GO:0008957
name: phenylacetaldehyde dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+." [EC:1.2.1.39]


id: GO:0008960
name: phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose." [EC:2.7.8.20]


id: GO:0008961
name: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein." [PMID:8051048]


id: GO:0008962
name: phosphatidylglycerophosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate." [EC:3.1.3.27]


id: GO:0008963
name: phospho-N-acetylmuramoyl-pentapeptide-transferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol." [EC:2.7.8.13]


id: GO:0008965
name: phosphoenolpyruvate-protein phosphotransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine." [EC:2.7.3.9]


id: GO:0008966
name: phosphoglucosamine mutase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate." [EC:5.4.2.10, RHEA:23427]


id: GO:0008967
name: phosphoglycolate phosphatase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate." [EC:3.1.3.18, RHEA:14372]


id: GO:0008968
name: D-sedoheptulose 7-phosphate isomerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate." [MetaCyc:RXN0-4301, PMID:11279237, PMID:8631969]


id: GO:0008970
name: phosphatidylcholine 1-acylhydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate." [EC:3.1.1.32]


id: GO:0008972
name: phosphomethylpyrimidine kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine." [EC:2.7.4.7]


id: GO:0008974
name: phosphoribulokinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.19, RHEA:19368]


id: GO:0008975
name: obsolete pitrilysin activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon." [EC:3.4.24.55]


id: GO:0008977
name: prephenate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH." [EC:1.3.1.12, RHEA:13872]


id: GO:0008978
name: obsolete prepilin peptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine." [EC:3.4.23.43]


id: GO:0008979
name: prophage integrase activity
namespace: molecular_function
def:
  "Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA." [GOC:jl]


id: GO:0008982
name: protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
namespace: molecular_function
def:
  "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [EC:2.7.1.69, GOC:mtg_transport, http://www.ucs.mun.ca/~n55lrb/general_pts.html, ISBN:0815340729, TC:4.A.-.-.-]


id: GO:0008983
name: protein-glutamate O-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester." [EC:2.1.1.80, RESID:AA0072]


id: GO:0008984
name: protein-glutamate methylesterase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol." [EC:3.1.1.61, RESID:AA0072]


id: GO:0008985
name: obsolete pyruvate dehydrogenase (cytochrome) activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1." [EC:1.2.2.2]


id: GO:0008986
name: pyruvate, water dikinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate." [EC:2.7.9.2, RHEA:11367]


id: GO:0008987
name: quinolinate synthetase A activity
namespace: molecular_function
def:
  "Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate." [GOC:jl, MetaCyc:QUINOLINATE-SYNTHA-RXN]


id: GO:0008988
name: rRNA (adenine-N6-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine." [EC:2.1.1.48]


id: GO:0008989
name: rRNA (guanine-N1-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine." [EC:2.1.1.51]


id: GO:0008990
name: rRNA (guanine-N2-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine." [EC:2.1.1.52]


id: GO:0008991
name: obsolete serine-type signal peptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism." [GOC:mah]


id: GO:0008994
name: rhamnulose-1-phosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde." [EC:4.1.2.19]


id: GO:0008995
name: ribonuclease E activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990]


id: GO:0008996
name: ribonuclease G activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990]


id: GO:0008997
name: ribonuclease R activity
namespace: molecular_function
def:
  "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides." [PMID:11948193]


id: GO:0008998
name: ribonucleoside-triphosphate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin." [EC:1.17.4.2]


id: GO:0008999
name: ribosomal-protein-alanine N-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine." [EC:2.3.1.128]


id: GO:0009000
name: selenocysteine lyase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor." [EC:4.4.1.16]


id: GO:0009001
name: serine O-acetyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA." [EC:2.3.1.30, RHEA:24563]


id: GO:0009002
name: serine-type D-Ala-D-Ala carboxypeptidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine." [EC:3.4.16.4]


id: GO:0009004
name: obsolete signal peptidase I activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor." [EC:3.4.21.89]


id: GO:0009005
name: obsolete signal peptidase II activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group." [EC:3.4.23.36]


id: GO:0009007
name: site-specific DNA-methyltransferase (adenine-specific) activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine." [EC:2.1.1.72]


id: GO:0009009
name: site-specific recombinase activity
namespace: molecular_function
def:
  "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences." [GOC:elh]


id: GO:0009010
name: sorbitol-6-phosphate 2-dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.140]


id: GO:0009011
name: starch synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1)." [EC:2.4.1.21]


id: GO:0009012
name: aminoglycoside 3''-adenylyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+)." [EC:2.7.7.47, RHEA:20248]


id: GO:0009013
name: succinate-semialdehyde dehydrogenase [NAD(P)+] activity
namespace: molecular_function
def:
  "Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+." [EC:1.2.1.16]


id: GO:0009014
name: succinyl-diaminopimelate desuccinylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate." [EC:3.5.1.18, RHEA:22611]


id: GO:0009015
name: N-succinylarginine dihydrolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+)." [EC:3.5.3.23, RHEA:19536]


id: GO:0009016
name: succinyldiaminopimelate transaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate." [EC:2.6.1.17, RHEA:11963]


id: GO:0009017
name: succinylglutamate desuccinylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate." [EC:3.5.1.96, RHEA:15172]


id: GO:0009018
name: sucrose phosphorylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate." [EC:2.4.1.7]


id: GO:0009019
name: tRNA (guanine-N1-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine." [EC:2.1.1.31]


id: GO:0009020
name: tRNA (guanosine-2'-O-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine." [EC:2.1.1.34]


id: GO:0009022
name: tRNA nucleotidyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate." [EC:2.7.7.56]


id: GO:0009023
name: obsolete tRNA sulfurtransferase
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide." [EC:2.8.1.4, GOC:go_curators]


id: GO:0009024
name: tagatose-6-phosphate kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate." [EC:2.7.1.144]


id: GO:0009025
name: tagatose-bisphosphate aldolase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate." [EC:4.1.2.40, RHEA:22951]


id: GO:0009026
name: tagaturonate reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH." [EC:1.1.1.58, RHEA:17816]


id: GO:0009028
name: tartronate-semialdehyde synthase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2)." [EC:4.1.1.47, RHEA:10139]


id: GO:0009029
name: tetraacyldisaccharide 4'-kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a)." [EC:2.7.1.130, RHEA:20703]


id: GO:0009030
name: thiamine-phosphate kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate." [EC:2.7.4.16, RHEA:15916]


id: GO:0009032
name: thymidine phosphorylase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate." [EC:2.4.2.4]


id: GO:0009033
name: trimethylamine-N-oxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O." [EC:1.6.6.9]


id: GO:0009034
name: tryptophanase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate." [EC:4.1.99.1, RHEA:19556]


id: GO:0009035
name: Type I site-specific deoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA." [EC:3.1.21.3, PMID:15788748]


id: GO:0009036
name: Type II site-specific deoxyribonuclease activity
namespace: molecular_function
def:
  "Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site." [EC:3.1.21.4, PMID:12654995]


id: GO:0009037
name: tyrosine-based site-specific recombinase activity
namespace: molecular_function
def:
  "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site." [GOC:elh, PMID:11090626]


id: GO:0009038
name: undecaprenol kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate." [EC:2.7.1.66, RHEA:23755]


id: GO:0009040
name: ureidoglycolate dehydrogenase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+." [EC:1.1.1.154, PMID:23284870]


id: GO:0009042
name: valine-pyruvate transaminase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine." [EC:2.6.1.66, RHEA:22915]


id: GO:0009044
name: xylan 1,4-beta-xylosidase activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini." [EC:3.2.1.37]


id: GO:0009046
name: zinc D-Ala-D-Ala carboxypeptidase activity
namespace: molecular_function
def:
  "Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine." [EC:3.4.17.14]


id: GO:0009047
name: dosage compensation by hyperactivation of X chromosome
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster." [GOC:jl, ISBN:0140512888, PMID:11498577]


id: GO:0009048
name: dosage compensation by inactivation of X chromosome
namespace: biological_process
def:
  "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex." [GOC:jl, GOC:pr, ISBN:0140512888, PMID:11498577]


id: GO:0009049
name: obsolete aspartic-type signal peptidase activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism." [GOC:mah]


id: GO:0009050
name: glycopeptide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glycopeptides, any compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide." [GOC:go_curators, ISBN:0198506732]


id: GO:0009051
name: pentose-phosphate shunt, oxidative branch
namespace: biological_process
def:
  "The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2)." [ISBN:0198506732, MetaCyc:OXIDATIVEPENT-PWY]


id: GO:0009052
name: pentose-phosphate shunt, non-oxidative branch
namespace: biological_process
def:
  "The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P." [ISBN:0198506732, MetaCyc:NONOXIPENT-PWY]


id: GO:0009055
name: electron carrier activity
namespace: molecular_function
def:
  "Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient." [ISBN:0198506732]


id: GO:0009056
name: catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684]


id: GO:0009057
name: macromolecule catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah]


id: GO:0009058
name: biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684]


id: GO:0009059
name: macromolecule biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [CHEBI:33694, GOC:mah]


id: GO:0009060
name: aerobic respiration
namespace: biological_process
def:
  "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor." [GOC:das, GOC:jl, ISBN:0140513590]


id: GO:0009061
name: anaerobic respiration
namespace: biological_process
def:
  "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor." [GOC:das, GOC:jl, ISBN:0140513590]


id: GO:0009062
name: fatty acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:go_curators]


id: GO:0009063
name: cellular amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai]


id: GO:0009064
name: glutamine family amino acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]


id: GO:0009065
name: glutamine family amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]


id: GO:0009066
name: aspartate family amino acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai]


id: GO:0009067
name: aspartate family amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai]


id: GO:0009068
name: aspartate family amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai]


id: GO:0009069
name: serine family amino acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai]


id: GO:0009070
name: serine family amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai]


id: GO:0009071
name: serine family amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai]


id: GO:0009072
name: aromatic amino acid family metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators]


id: GO:0009073
name: aromatic amino acid family biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators]


id: GO:0009074
name: aromatic amino acid family catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators]


id: GO:0009075
name: obsolete histidine family amino acid metabolic process
namespace: biological_process
def:
  "OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family." [GOC:ai]


id: GO:0009076
name: obsolete histidine family amino acid biosynthetic process
namespace: biological_process
def:
  "OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family." [GOC:ai]


id: GO:0009077
name: obsolete histidine family amino acid catabolic process
namespace: biological_process
def:
  "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family." [GOC:ai]


id: GO:0009078
name: pyruvate family amino acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl]


id: GO:0009079
name: pyruvate family amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl]


id: GO:0009080
name: pyruvate family amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl]


id: GO:0009081
name: branched-chain amino acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [CHEBI:22918, GOC:ai]


id: GO:0009082
name: branched-chain amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [CHEBI:22918, GOC:ai]


id: GO:0009083
name: branched-chain amino acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [GOC:ai]


id: GO:0009084
name: glutamine family amino acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai]


id: GO:0009085
name: lysine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators]


id: GO:0009086
name: methionine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]


id: GO:0009087
name: methionine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]


id: GO:0009088
name: threonine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732]


id: GO:0009089
name: lysine biosynthetic process via diaminopimelate
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate." [GOC:go_curators]


id: GO:0009090
name: homoserine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732]


id: GO:0009091
name: homoserine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732]


id: GO:0009092
name: homoserine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine." [GOC:go_curators, ISBN:0198506732]


id: GO:0009093
name: cysteine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators]


id: GO:0009094
name: L-phenylalanine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid." [CHEBI:17295, GOC:go_curators, GOC:jsg, GOC:mah]


id: GO:0009095
name: aromatic amino acid family biosynthetic process, prephenate pathway
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate." [GOC:mah, ISBN:0471331309]


id: GO:0009097
name: isoleucine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai]


id: GO:0009098
name: leucine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid." [GOC:ai]


id: GO:0009099
name: valine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid." [GOC:ai]


id: GO:0009100
name: glycoprotein metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732]


id: GO:0009101
name: glycoprotein biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732]


id: GO:0009102
name: biotin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid." [ISBN:0198506732]


id: GO:0009103
name: lipopolysaccharide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria." [GOC:ai, GOC:mr]


id: GO:0009104
name: lipopolysaccharide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria." [GOC:ai]


id: GO:0009106
name: lipoate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid." [GOC:ai, ISBN:0198506732]


id: GO:0009107
name: lipoate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid." [GOC:ai, ISBN:0198506732]


id: GO:0009108
name: coenzyme biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai]


id: GO:0009109
name: coenzyme catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai]


id: GO:0009110
name: vitamin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:go_curators, ISBN:0198506732]


id: GO:0009111
name: vitamin catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai]


id: GO:0009112
name: nucleobase metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma]


id: GO:0009113
name: purine nucleobase biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine." [CHEBI:26386, GOC:go_curators, ISBN:0198506732]


id: GO:0009114
name: hypoxanthine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate." [GOC:go_curators]


id: GO:0009115
name: xanthine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids." [GOC:go_curators]


id: GO:0009116
name: nucleoside metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine)." [GOC:ma]


id: GO:0009117
name: nucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates)." [GOC:ma]


id: GO:0009118
name: regulation of nucleoside metabolic process
namespace: biological_process
def:
  "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators]


id: GO:0009119
name: ribonucleoside metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [CHEBI:18254, GOC:jl]


id: GO:0009120
name: deoxyribonucleoside metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713]


id: GO:0009123
name: nucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009124
name: nucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009125
name: nucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009126
name: purine nucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009127
name: purine nucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009128
name: purine nucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009129
name: pyrimidine nucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009130
name: pyrimidine nucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009131
name: pyrimidine nucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009132
name: nucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009133
name: nucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009134
name: nucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009135
name: purine nucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009136
name: purine nucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009137
name: purine nucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009138
name: pyrimidine nucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009139
name: pyrimidine nucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009140
name: pyrimidine nucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009141
name: nucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009142
name: nucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009143
name: nucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009144
name: purine nucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009145
name: purine nucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009146
name: purine nucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009147
name: pyrimidine nucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009148
name: pyrimidine nucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009149
name: pyrimidine nucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009150
name: purine ribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009151
name: purine deoxyribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009152
name: purine ribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009153
name: purine deoxyribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009154
name: purine ribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009155
name: purine deoxyribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009156
name: ribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009157
name: deoxyribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009158
name: ribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009159
name: deoxyribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009161
name: ribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009162
name: deoxyribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009163
name: nucleoside biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713]


id: GO:0009164
name: nucleoside catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl]


id: GO:0009165
name: nucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)." [GOC:go_curators]


id: GO:0009166
name: nucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)." [GOC:go_curators]


id: GO:0009167
name: purine ribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009168
name: purine ribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009169
name: purine ribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009170
name: purine deoxyribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009171
name: purine deoxyribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009172
name: purine deoxyribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009173
name: pyrimidine ribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009174
name: pyrimidine ribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009175
name: pyrimidine ribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009176
name: pyrimidine deoxyribonucleoside monophosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009177
name: pyrimidine deoxyribonucleoside monophosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009178
name: pyrimidine deoxyribonucleoside monophosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009179
name: purine ribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009180
name: purine ribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009181
name: purine ribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009182
name: purine deoxyribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009183
name: purine deoxyribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009184
name: purine deoxyribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009185
name: ribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009186
name: deoxyribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009187
name: cyclic nucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732]


id: GO:0009188
name: ribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009189
name: deoxyribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009190
name: cyclic nucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732]


id: GO:0009191
name: ribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009192
name: deoxyribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009193
name: pyrimidine ribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009194
name: pyrimidine ribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009195
name: pyrimidine ribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009196
name: pyrimidine deoxyribonucleoside diphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009197
name: pyrimidine deoxyribonucleoside diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009198
name: pyrimidine deoxyribonucleoside diphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009199
name: ribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009200
name: deoxyribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009201
name: ribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009202
name: deoxyribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009203
name: ribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009204
name: deoxyribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009205
name: purine ribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009206
name: purine ribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009207
name: purine ribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009208
name: pyrimidine ribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009209
name: pyrimidine ribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009210
name: pyrimidine ribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009211
name: pyrimidine deoxyribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009212
name: pyrimidine deoxyribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009213
name: pyrimidine deoxyribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009214
name: cyclic nucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732]


id: GO:0009215
name: purine deoxyribonucleoside triphosphate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009216
name: purine deoxyribonucleoside triphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009217
name: purine deoxyribonucleoside triphosphate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009218
name: pyrimidine ribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009219
name: pyrimidine deoxyribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009220
name: pyrimidine ribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009221
name: pyrimidine deoxyribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009222
name: pyrimidine ribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009223
name: pyrimidine deoxyribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009224
name: CMP biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate." [ISBN:0198506732]


id: GO:0009225
name: nucleotide-sugar metabolic process
namespace: biological_process
def:
  "The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732]


id: GO:0009226
name: nucleotide-sugar biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732]


id: GO:0009227
name: nucleotide-sugar catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732]


id: GO:0009228
name: thiamine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [CHEBI:18385, GOC:jl, ISBN:0198506732]


id: GO:0009229
name: thiamine diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle." [CHEBI:45931, GOC:jl, ISBN:0140512713]


id: GO:0009230
name: thiamine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [CHEBI:18385, GOC:jl, ISBN:0198506732]


id: GO:0009231
name: riboflavin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html]


id: GO:0009232
name: riboflavin catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html]


id: GO:0009233
name: menaquinone metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k]


id: GO:0009234
name: menaquinone biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k]


id: GO:0009235
name: cobalamin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:go_curators]


id: GO:0009236
name: cobalamin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:jl, ISBN:0198506732]


id: GO:0009237
name: siderophore metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action." [ISBN:0198547684]


id: GO:0009238
name: enterobactin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway." [ISBN:0198547684]


id: GO:0009239
name: enterobactin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway." [GOC:go_curators]


id: GO:0009240
name: isopentenyl diphosphate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids." [GOC:jl, ISBN:0198506732]


id: GO:0009242
name: colanic acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide." [GOC:ai]


id: GO:0009243
name: O antigen biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide." [ISBN:0198506732]


id: GO:0009244
name: lipopolysaccharide core region biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues." [ISBN:0198506732]


id: GO:0009245
name: lipid A biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of six fatty acyl chains linked to two glucosamine residues." [ISBN:0198506732]


id: GO:0009246
name: enterobacterial common antigen biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria." [GOC:ma]


id: GO:0009247
name: glycolipid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." [CHEBI:33563, GOC:go_curators]


id: GO:0009248
name: K antigen biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens." [ISBN:0198506732]


id: GO:0009250
name: glucan biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators]


id: GO:0009251
name: glucan catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators]


id: GO:0009252
name: peptidoglycan biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls." [http://www.dsmz.de/species/murein.htm, ISBN:0198506732]


id: GO:0009253
name: peptidoglycan catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls." [http://www.dsmz.de/species/murein.htm, ISBN:0198506732]


id: GO:0009254
name: peptidoglycan turnover
namespace: biological_process
def:
  "The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall." [GOC:jl]


id: GO:0009255
name: Entner-Doudoroff pathway through 6-phosphogluconate
namespace: biological_process
def:
  "A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it." [GOC:jl, MetaCyc:ENTNER-DOUDOROFF-PWY-I, PMID:12921356]


id: GO:0009256
name: 10-formyltetrahydrofolate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai]


id: GO:0009257
name: 10-formyltetrahydrofolate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai]


id: GO:0009258
name: 10-formyltetrahydrofolate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai]


id: GO:0009259
name: ribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009260
name: ribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009261
name: ribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009262
name: deoxyribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009263
name: deoxyribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009264
name: deoxyribonucleotide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732]


id: GO:0009265
name: 2'-deoxyribonucleotide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:mah]


id: GO:0009266
name: response to temperature stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." [GOC:hb]


id: GO:0009267
name: cellular response to starvation
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment." [GOC:jl]


id: GO:0009268
name: response to pH
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:jl, http://en.wikipedia.org/wiki/PH]


id: GO:0009269
name: response to desiccation
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." [GOC:jl]


id: GO:0009270
name: response to humidity
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere." [GOC:jl]


id: GO:0009271
name: phage shock
namespace: biological_process
def:
  "A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage." [GOC:add, GOC:jl, PMID:15485810, PMID:16045608]


id: GO:0009272
name: fungal-type cell wall biogenesis
namespace: biological_process
def:
  "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin." [GOC:go_curators, GOC:mtg_sensu]


id: GO:0009273
name: peptidoglycan-based cell wall biogenesis
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli." [GOC:go_curators]


id: GO:0009274
name: peptidoglycan-based cell wall
namespace: cellular_component
def:
  "A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli." [GOC:mlg, ISBN:0815108893]


id: GO:0009275
name: Gram-positive-bacterium-type cell wall
namespace: cellular_component
def:
  "A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria." [GOC:mlg, ISBN:0051406910, ISBN:0815108893]


id: GO:0009276
name: Gram-negative-bacterium-type cell wall
namespace: cellular_component
def:
  "The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain." [GOC:mlg, ISBN:0815108893]


id: GO:0009277
name: fungal-type cell wall
namespace: cellular_component
def:
  "A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure." [GOC:mcc, GOC:mtg_sensu, ISBN:3540601864, PMID:11283274, PMID:16927300, PMID:3319422]


id: GO:0009278
name: obsolete murein sacculus
namespace: cellular_component
def:
  "OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria." [GOC:ma]


id: GO:0009279
name: cell outer membrane
namespace: cellular_component
def:
  "A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures." [GOC:md, GOC:mtg_sensu, ISBN:0135712254]


id: GO:0009280
name: obsolete cell wall inner membrane
namespace: cellular_component
def:
  "OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus." [GOC:ma]


id: GO:0009288
name: bacterial-type flagellum
namespace: cellular_component
def:
  "A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope." [GOC:cilia, GOC:jh2, GOC:krc, GOC:mtg_sensu, http:en.wikipedia.org/wiki/Flagellum#Bacterial, PMID:7787060]


id: GO:0009289
name: pilus
namespace: cellular_component
def:
  "A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter." [GOC:pamgo_curators]


id: GO:0009290
name: DNA import into cell involved in transformation
namespace: biological_process
def:
  "The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell." [GOC:ai]


id: GO:0009291
name: unidirectional conjugation
namespace: biological_process
def:
  "The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in Prokaryotes." [ISBN:0387520546]


id: GO:0009292
name: genetic transfer
namespace: biological_process
def:
  "In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual." [GOC:clt]


id: GO:0009293
name: transduction
namespace: biological_process
def:
  "The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector." [ISBN:0198506732]


id: GO:0009294
name: DNA mediated transformation
namespace: biological_process
def:
  "The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material." [ISBN:0716720094, Wikipedia:Transformation_(genetics)]


id: GO:0009295
name: nucleoid
namespace: cellular_component
def:
  "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." [GOC:bm, GOC:ma, ISBN:3540076689]


id: GO:0009296
name: obsolete flagellum assembly
namespace: biological_process
def:
  "The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers." [GOC:curators, ISBN:0815316194]


id: GO:0009297
name: pilus assembly
namespace: biological_process
def:
  "The assembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles." [GOC:dgh, GOC:mcc2, GOC:tb]


id: GO:0009298
name: GDP-mannose biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate." [GOC:ai]


id: GO:0009300
name: antisense RNA transcription
namespace: biological_process
def:
  "The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:jl]


id: GO:0009303
name: rRNA transcription
namespace: biological_process
def:
  "The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template." [GOC:jl, ISBN:0198506732]


id: GO:0009307
name: DNA restriction-modification system
namespace: biological_process
def:
  "A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme." [GOC:jl, UniProtKB-KW:KW-0680]


id: GO:0009308
name: amine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]


id: GO:0009309
name: amine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]


id: GO:0009310
name: amine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]


id: GO:0009311
name: oligosaccharide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732]


id: GO:0009312
name: oligosaccharide biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732]


id: GO:0009313
name: oligosaccharide catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732]


id: GO:0009314
name: response to radiation
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation]


id: GO:0009316
name: 3-isopropylmalate dehydratase complex
namespace: cellular_component
def:
  "A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate." [BRENDA:4.2.1.33, GOC:jl, MetaCyc:3-ISOPROPYLMALISOM-CPLX, PMID:7026530]


id: GO:0009317
name: acetyl-CoA carboxylase complex
namespace: cellular_component
def:
  "A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex." [GOC:jl, GOC:mah, PMID:12121720]


id: GO:0009318
name: exodeoxyribonuclease VII complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA." [EC:3.1.11.6]


id: GO:0009319
name: cytochrome o ubiquinol oxidase complex
namespace: cellular_component
def:
  "A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups." [GOC:mah, MetaCyc:CYT-O-UBIOX-CPLX, PMID:11017202, PMID:3052268]


id: GO:0009321
name: alkyl hydroperoxide reductase complex
namespace: cellular_component
def:
  "An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides." [BRENDA:1.11.1.15, GOC:jl, PMID:2649484]


id: GO:0009322
name: trimethylamine-N-oxide reductase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine." [EC:1.6.6.9]


id: GO:0009323
name: ribosomal-protein-alanine N-acetyltransferase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine." [EC:2.3.1.128]


id: GO:0009325
name: nitrate reductase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor." [EC:1.7.99.4]


id: GO:0009326
name: formate dehydrogenase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2)." [EC:1.2.1.2]


id: GO:0009327
name: NAD(P)+ transhydrogenase complex (AB-specific)
namespace: cellular_component
def:
  "A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified." [BRENDA:1.6.1.2, GOC:mah]


id: GO:0009328
name: phenylalanine-tRNA ligase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe)." [EC:6.1.1.20]


id: GO:0009329
name: acetate CoA-transferase complex
namespace: cellular_component
def:
  "A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA." [GOC:jl, PMID:2719476, PMID:8423010]


id: GO:0009331
name: glycerol-3-phosphate dehydrogenase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate." [EC:1.1.5.3]


id: GO:0009332
name: glutamate-tRNA ligase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu)." [EC:6.1.1.17]


id: GO:0009333
name: cysteine synthase complex
namespace: cellular_component
def:
  "Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A." [EC:4.2.99.8, MetaCyc:CYSSYNMULTI-CPLX]


id: GO:0009334
name: 3-phenylpropionate dioxygenase complex
namespace: cellular_component
def:
  "Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol)." [GOC:jl, MetaCyc:HCAMULTI-CPLX, PMID:9603882]


id: GO:0009335
name: obsolete holo-[acyl-carrier protein] synthase complex
namespace: cellular_component
def:
  "OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein]." [EC:2.7.8.7]


id: GO:0009337
name: sulfite reductase complex (NADPH)
namespace: cellular_component
def:
  "A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide." [BRENDA:1.8.1.2, GOC:jl]


id: GO:0009338
name: exodeoxyribonuclease V complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA." [EC:3.1.11.5]


id: GO:0009339
name: glycolate oxidase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN)." [EC:1.1.3.15]


id: GO:0009340
name: DNA topoisomerase IV complex
namespace: cellular_component
def:
  "A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA." [GOC:jl, PMID:7783632]


id: GO:0009341
name: beta-galactosidase complex
namespace: cellular_component
def:
  "A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species." [BRENDA:3.2.1.2, EC:3.2.1.23, PMID:15950161]


id: GO:0009343
name: biotin carboxylase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2)." [EC:6.3.4.14]


id: GO:0009345
name: glycine-tRNA ligase complex
namespace: cellular_component
def:
  "A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly)." [EC:6.1.1.14, GOC:jl, PMID:15733854]


id: GO:0009346
name: citrate lyase complex
namespace: cellular_component
def:
  "Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity." [EC:4.1.3.6, MetaCyc:ACECITLY-CPLX]


id: GO:0009347
name: aspartate carbamoyltransferase complex
namespace: cellular_component
def:
  "A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides." [PMID:10447693]


id: GO:0009348
name: ornithine carbamoyltransferase complex
namespace: cellular_component
def:
  "A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline." [EC:2.1.3.3, GOC:mah]


id: GO:0009349
name: riboflavin synthase complex
namespace: cellular_component
def:
  "An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine." [EC:2.5.1.9]


id: GO:0009350
name: ethanolamine ammonia-lyase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia." [EC:4.3.1.7]


id: GO:0009351
name: obsolete dihydrolipoamide S-acyltransferase complex
namespace: cellular_component
def:
  "OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide." [EC:2.3.1.12]


id: GO:0009353
name: mitochondrial oxoglutarate dehydrogenase complex
namespace: cellular_component
def:
  "A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus." [GOC:mtg_sensu, MetaCyc:CPLX66-42, PMID:10848975]


id: GO:0009354
name: obsolete dihydrolipoamide S-succinyltransferase complex
namespace: cellular_component
def:
  "OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex." [EC:2.3.1.61]


id: GO:0009355
name: DNA polymerase V complex
namespace: cellular_component
def:
  "A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis." [PMID:10430871, PMID:10542196]


id: GO:0009356
name: aminodeoxychorismate synthase complex
namespace: cellular_component
def:
  "A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity." [PMID:2251281, PMID:7592344]


id: GO:0009357
name: protein-N(PI)-phosphohistidine-sugar phosphotransferase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system." [EC:2.7.1.69]


id: GO:0009359
name: Type II site-specific deoxyribonuclease complex
namespace: cellular_component
def:
  "A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995]


id: GO:0009360
name: DNA polymerase III complex
namespace: cellular_component
def:
  "The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork." [PMID:11525729, PMID:12940977, UniProt:P06710]


id: GO:0009361
name: succinate-CoA ligase complex (ADP-forming)
namespace: cellular_component
def:
  "A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP." [EC:6.2.1.5, GOC:jl]


id: GO:0009366
name: enterobactin synthetase complex
namespace: cellular_component
def:
  "A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway." [MetaCyc:ENTMULTI-CPLX, PMID:9485415]


id: GO:0009367
name: obsolete prepilin peptidase complex
namespace: cellular_component
def:
  "OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group." [EC:3.4.23.43]


id: GO:0009368
name: endopeptidase Clp complex
namespace: cellular_component
def:
  "A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form." [GOC:mah, PMID:11352464]


id: GO:0009371
name: positive regulation of transcription by pheromones
namespace: biological_process
def:
  "Any process involving pheromones that activates or increases the rate of transcription." [GOC:go_curators]


id: GO:0009372
name: quorum sensing
namespace: biological_process
def:
  "The process in which single-celled organisms monitor their population density by detecting the concentration of small, diffusible signal molecules produced by the cells themselves." [PMID:15716452, PMID:8288518]


id: GO:0009373
name: regulation of transcription by pheromones
namespace: biological_process
def:
  "Any process involving pheromones that modulates the frequency, rate or extent of transcription." [GOC:go_curators]


id: GO:0009374
name: biotin binding
namespace: molecular_function
def:
  "Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:jl, ISBN:0198506732]


id: GO:0009375
name: ferredoxin hydrogenase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances." [EC:1.12.7.2]


id: GO:0009376
name: HslUV protease complex
namespace: cellular_component
def:
  "A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer." [GOC:bhm, PMID:12670962, UniProt:P0A6H5]


id: GO:0009377
name: obsolete HslUV protease activity
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins." [GOC:mah, PMID:10368141]


id: GO:0009378
name: four-way junction helicase activity
namespace: molecular_function
def:
  "Catalysis of the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions." [GOC:jl, PMID:9442895]


id: GO:0009379
name: Holliday junction helicase complex
namespace: cellular_component
def:
  "A DNA helicase complex that forms part of a Holliday junction resolvase complex, where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA." [PMID:16935884, PMID:9442895]


id: GO:0009380
name: excinuclease repair complex
namespace: cellular_component
def:
  "Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap." [GOC:mah, GOC:mlg, PMID:12145219, PMID:15192705]


id: GO:0009381
name: excinuclease ABC activity
namespace: molecular_function
def:
  "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind." [GOC:mah, PMID:15192705]


id: GO:0009383
name: rRNA (cytosine-C5-)-methyltransferase activity
namespace: molecular_function
def:
  "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA." [GOC:imk, PMID:10026269, PMID:18786544]


id: GO:0009384
name: N-acylmannosamine kinase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate." [EC:2.7.1.60]


id: GO:0009385
name: N-acylmannosamine-6-phosphate 2-epimerase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate." [MetaCyc:NANE-RXN]


id: GO:0009386
name: translational attenuation
namespace: biological_process
def:
  "Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation." [PMID:15694341, PMID:15805513]


id: GO:0009389
name: dimethyl sulfoxide reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O." [UM-BBD_reactionID:r0207]


id: GO:0009390
name: dimethyl sulfoxide reductase complex
namespace: cellular_component
def:
  "An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide." [UM-BBD_enzymeID:e0188]


id: GO:0009392
name: N-acetyl-anhydromuramoyl-L-alanine amidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala." [MetaCyc:RXN0-5225]


id: GO:0009394
name: 2'-deoxyribonucleotide metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:mah]


id: GO:0009395
name: phospholipid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [ISBN:0198506732]


id: GO:0009396
name: folic acid-containing compound biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of folic acid and its derivatives." [GOC:ai]


id: GO:0009397
name: folic acid-containing compound catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives." [GOC:ai]


id: GO:0009398
name: FMN biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase." [CHEBI:17621, GOC:ai]


id: GO:0009399
name: nitrogen fixation
namespace: biological_process
def:
  "The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide." [Wikipedia:Nitrogen_fixation]


id: GO:0009400
name: receptor signaling protein serine/threonine phosphatase activity
namespace: molecular_function
def:
  "Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate." [GOC:bf, GOC:mah]


id: GO:0009401
name: phosphoenolpyruvate-dependent sugar phosphotransferase system
namespace: biological_process
def:
  "The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC." [http://www.ucs.mun.ca/~n55lrb/general_pts.html]


id: GO:0009403
name: toxin biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:go_curators]


id: GO:0009404
name: toxin metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:cab2]


id: GO:0009405
name: pathogenesis
namespace: biological_process
def:
  "The set of specific processes that generate the ability of an organism to cause disease in another." [GOC:go_curators]


id: GO:0009407
name: toxin catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:go_curators]


id: GO:0009408
name: response to heat
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:lr]


id: GO:0009409
name: response to cold
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:lr]


id: GO:0009410
name: response to xenobiotic stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms." [GOC:jl]


id: GO:0009411
name: response to UV
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:hb]


id: GO:0009412
name: obsolete response to heavy metal
namespace: biological_process
def:
  "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:ai]


id: GO:0009413
name: response to flooding
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water." [GOC:lr]


id: GO:0009414
name: response to water deprivation
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." [GOC:lr]


id: GO:0009415
name: response to water
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." [GOC:jl]


id: GO:0009416
name: response to light stimulus
namespace: biological_process
def:
  "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089]


id: GO:0009420
name: bacterial-type flagellum filament
namespace: cellular_component
def:
  "The long (approximately 20 nm), thin external structure of the flagellum, which acts as a propeller. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009421
name: bacterial-type flagellum filament cap
namespace: cellular_component
def:
  "The proteinaceous structure at the distal tip of the flagellar filament. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009422
name: bacterial-type flagellum hook-filament junction
namespace: cellular_component
def:
  "The region of the flagellum where the hook and filament meet. Examples of this component are found in bacteria." [GOC:mah, GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009423
name: chorismate biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds." [GOC:sm, ISBN:0198547684]


id: GO:0009424
name: bacterial-type flagellum hook
namespace: cellular_component
def:
  "The portion of the flagellum that connects the filament to the basal body. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009425
name: bacterial-type flagellum basal body
namespace: cellular_component
def:
  "One of the three major substructures of the flagellin-based flagellum; a structure consisting of a rod, a series of rings, the Mot proteins, the switch complex and the flagellum-specific export apparatus. The rings anchor the flagellum to the cytoplasmic membrane (MS ring), the peptidoglycan (P ring) and the outer membrane (L ring). Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009426
name: bacterial-type flagellum basal body, distal rod
namespace: cellular_component
def:
  "The portion of the central rod of the flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192]


id: GO:0009427
name: bacterial-type flagellum basal body, distal rod, L ring
namespace: cellular_component
def:
  "One of the rings of the flagellar basal body; anchors the basal body to the outer membrane. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009428
name: bacterial-type flagellum basal body, distal rod, P ring
namespace: cellular_component
def:
  "One of the rings of the flagellar basal body; anchors the basal body to the peptidoglycan layer. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009429
name: bacterial-type flagellum basal body, proximal rod
namespace: cellular_component
def:
  "The portion of the central rod of the flagellar basal body that is proximal to the cell membrane; proximal rod connects the distal rod to the flagellar motor. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192]


id: GO:0009431
name: bacterial-type flagellum basal body, MS ring
namespace: cellular_component
def:
  "One of the rings of the flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009433
name: bacterial-type flagellum basal body, C ring
namespace: cellular_component
def:
  "Cytoplasmic ring located at the base of the flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. Examples of this component are found in bacteria." [GOC:mtg_sensu, PMID:10572114, PMID:12624192]


id: GO:0009435
name: NAD biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:jl, ISBN:0618254153]


id: GO:0009436
name: glyoxylate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH." [ISBN:0198506732]


id: GO:0009437
name: carnitine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:jl, ISBN:0198506732]


id: GO:0009438
name: methylglyoxal metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid." [CHEBI:17158, GOC:ai]


id: GO:0009439
name: cyanate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid." [ISBN:0198506732]


id: GO:0009440
name: cyanate catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid." [ISBN:0198506732]


id: GO:0009441
name: glycolate metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid)." [GOC:ai, ISBN:0198506732]


id: GO:0009442
name: allantoin assimilation pathway
namespace: biological_process
def:
  "The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP." [MetaCyc:PWY0-41]


id: GO:0009443
name: pyridoxal 5'-phosphate salvage
namespace: biological_process
def:
  "Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis." [GOC:jl]


id: GO:0009444
name: pyruvate oxidation
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate." [MetaCyc:PYRUVOX-PWY]


id: GO:0009445
name: putrescine metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine." [GOC:ai]


id: GO:0009446
name: putrescine biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine." [GOC:go_curators, ISBN:0198506732]


id: GO:0009447
name: putrescine catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine." [GOC:ai]


id: GO:0009448
name: gamma-aminobutyric acid metabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [ISBN:0198506732]


id: GO:0009449
name: gamma-aminobutyric acid biosynthetic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [GOC:ai]


id: GO:0009450
name: gamma-aminobutyric acid catabolic process
namespace: biological_process
def:
  "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [GOC:ai]


id: GO:0009451
name: RNA modification
namespace: biological_process
def:
  "The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically." [GOC:go_curators, ISBN:1555811337]


id: GO:0009452
name: 7-methylguanosine RNA capping
namespace: biological_process
def:
  "The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript." [GOC:vw, PMID:9266685]


id: GO:0009453
name: energy taxis
namespace: biological_process
def:
  "The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates." [GOC:jl, PMID:11029423]


id: GO:0009454
name: aerotaxis
namespace: biological_process
def:
  "The directed movement of a motile cell or organism in response to environmental oxygen." [GOC:jl, ISBN:0192801023]


id: GO:0009455
name: redox taxis
namespace: biological_process
def:
  "The directed movement of a motile cell or organism in response to redox potential." [GOC:jl, PMID:11029423]


id: GO:0009457
name: obsolete flavodoxin
namespace: molecular_function
def:
  "OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide." [GOC:kd]


id: GO:0009458
name: obsolete cytochrome
namespace: molecular_function
def:
  "OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom." [PMID:1655423]


id: GO:0009460
name: obsolete cytochrome b
namespace: molecular_function
def:
  "OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b)." [GOC:kd]


id: GO:0009461
name: obsolete cytochrome c
namespace: molecular_function
def:
  "OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues." [GOC:kd]


id: GO:0009462
name: obsolete cytochrome d
namespace: molecular_function
def:
  "OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes." [GOC:kd, PMID:1655423]


id: GO:0009463
name: obsolete cytochrome b/b6
namespace: molecular_function
def:
  "OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis." [ISBN:0198547684]


id: GO:0009477
name: obsolete cytochrome c1
namespace: molecular_function
def:
  "OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c." [PMID:1655423]


id: GO:0009479
name: obsolete cytochrome f
namespace: molecular_function
def:
  "OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin." [PMID:1655423]


id: GO:0009481
name: obsolete aa3-type cytochrome c oxidase
namespace: molecular_function
def:
  "OBSOLETE. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1]


id: GO:0009486
name: cytochrome bo3 ubiquinol oxidase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]." [MetaCyc:RXN0-5268]


id: GO:0009487
name: obsolete glutaredoxin
namespace: molecular_function
def:
  "OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase." [GOC:kd]


id: GO:0009488
name: obsolete amicyanin
namespace: molecular_function
def:
  "OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c." [PMID:1655423]


id: GO:0009489
name: obsolete rubredoxin
namespace: molecular_function
def:
  "OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues." [GOC:kd]


id: GO:0009490
name: obsolete mononuclear iron electron carrier
namespace: molecular_function
def:
  "OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system." [GOC:ai]


id: GO:0009496
name: plastoquinol--plastocyanin reductase activity
namespace: molecular_function
def:
  "Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane." [EC:1.10.9.1]


id: GO:0009502
name: obsolete photosynthetic electron transport chain
namespace: cellular_component
def:
  "OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen)." [GOC:mtg_electron_transport, ISBN:014051403]


id: GO:0009503
name: thylakoid light-harvesting complex
namespace: cellular_component
def:
  "A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0198547684]


id: GO:0009504
name: cell plate
namespace: cellular_component
def:
  "The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells." [ISBN:0198547684]


id: GO:0009505
name: plant-type cell wall
namespace: cellular_component
def:
  "A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances." [ISBN:0471245208]


id: GO:0009506
name: plasmodesma
namespace: cellular_component
def:
  "A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [ISBN:0198506732]


id: GO:0009507
name: chloroplast
namespace: cellular_component
def:
  "A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." [ISBN:0471245208]


id: GO:0009509
name: chromoplast
namespace: cellular_component
def:
  "A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments." [ISBN:0471245208]


id: GO:0009510
name: plasmodesmatal desmotubule
namespace: cellular_component
def:
  "A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell." [http://biology.kenyon.edu/edwards/project/greg/pd.htm]


id: GO:0009511
name: plasmodesmatal endoplasmic reticulum
namespace: cellular_component
def:
  "Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells." [GOC:ai]


id: GO:0009512
name: cytochrome b6f complex
namespace: cellular_component
def:
  "Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species." [ISBN:0943883999, PMID:16228398, PMID:16352458]


id: GO:0009513
name: etioplast
namespace: cellular_component
def:
  "A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions." [ISBN:0943883999]


id: GO:0009514
name: glyoxysome
namespace: cellular_component
def:
  "A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds." [GOC:dhl, ISBN:0140514031]


id: GO:0009515
name: granal stacked thylakoid
namespace: cellular_component
def:
  "Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II." [GOC:lr]


id: GO:0009519
name: middle lamella
namespace: cellular_component
def:
  "Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells." [ISBN:0471245208]


id: GO:0009521
name: photosystem
namespace: cellular_component
def:
  "A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949]


id: GO:0009522
name: photosystem I
namespace: cellular_component
def:
  "A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation)." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949]


